Mariana Sá Pereira

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Glicobiologia

ORCID:

não disponível no Lattes


Formação:

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 1998 - 2002

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Mestrado | 1996 - 1998

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas - Licenciatura Ou Bacharelado | Graduação | 1991 - 1995
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:

(62.86% artigos com DOI)

Titulo DOI Ano
A low-anticoagulant heparin suppresses metastatic dissemination through the inhibition of tumor cell-platelets association 10.1016/j.biopha.2023.116108 2024
Heparins Sourced From Bovine and Porcine Mucosa Gain Exclusive Monographs in the Brazilian Pharmacopeia 10.3389/fmed.2019.00016 2019
Converting the Distinct Heparins Sourced from Bovine or Porcine Mucosa into a Single Anticoagulant Drug 10.1055/s-0039-1678663 2019
A unique fucosylated chondroitin sulfate type II with strikingly homogeneous and neatly distributed α-fucose branches 10.1093/glycob/cwy048 2018
Chemical and pharmacological aspects of neutralization of heparins from different animal sources by protamine 10.1111/jth.14221 2018
Systematic Analysis of Pharmaceutical Preparations of Chondroitin Sulfate Combined with Glucosamine 10.3390/ph10020038 2017
Structural and haemostatic features of pharmaceutical heparins from different animal sources: challenges to define thresholds separating distinct drugs 10.1038/srep35619 2016
Structural and functional analyses of biosimilar enoxaparins available in Brazil 10.1160/th14-05-0411 2015
Structural and functional analyses of bovine and porcine intestinal heparins confirm they are different drugs 10.1016/j.drudis.2014.07.004 2014
Sulfonation and anticoagulant activity of fungal exocellular β-(1→6)-d-glucan (lasiodiplodan) 10.1016/j.carbpol.2012.10.034 2013
Structure and haemostatic effects of generic versions of enoxaparin available for clinical use in Brazil: Similarity to the original drug 10.1160/TH11-09-0664 2012
Debate propositivo sobre os biossimilares de enoxaparina no Brasil 10.1590/S0066-782X2012000100019 2012
Residual keratan sulfate in chondroitin sulfate formulations for oral administration 10.1016/j.carbpol.2012.06.009 2012
Generic versions of enoxaparin available for clinical use in Brazil are similar to the original drug 10.1111/j.1538-7836.2011.04330.x 2011
Sulfated fucan from marine alga inhibits HeLa cells infection by HTLV-1 free particles: semi-quantitative analysis 10.1590/S0102-695X2011005000055 2011
Heparins from porcine and bovine intestinal mucosa: Are they similar drugs? 10.1160/TH09-11-0761 2010
Brown algae overproduce cell wall polysaccharides as a protection mechanism against the heavy metal toxicity 10.1016/j.marpolbul.2010.05.004 2010
Sulfonation and anticoagulant activity of botryosphaeran from Botryosphaeria rhodina MAMB-05 grown on fructose 10.1016/j.ijbiomac.2009.06.004 2009
Anticoagulant activity of a sulfated galactan: Serpin-independent effect and specific interaction with factor Xa 10.1160/TH09-04-0273 2009
Sulfated galactan is a catalyst of antithrombin-mediated inactivation of ?-thrombin 10.1016/j.bbagen.2008.05.006 2008
Controle da qualidade das preparações de heparina disponíveis no Brasil: implicações na cirurgia cardiovascular 10.1590/S0102-76382008000200004 2008
Serpin-independent anticoagulant activity of a fucosylated chondroitin sulfate 10.1160/TH08-04-0210 2008
Plasma rico em plaquetas e fatores de crescimento: técnica de preparo e utilização em cirurgia plástica 2006
Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecif removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity 2005
Mild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach forpreparing tailored sulfated oligosaccharide (aceito para publicação) 2005
Antithrombin-mediated Anticoagulant Activity of Sulfated Polysaccharides: Different Mechanisms for Heparin and Sulfated Galactans 2004
Ultrastructure of acidic polysaccharides from the cell walls of brown algae 2004
Is There a correlation between structure and anticoagulant action of sulfated galactans and sulfated fucans? 2002
Medicinal plants contain polisaccharides with anticoagulant activity mediated by heparin cofactor II 2002
2-O-sulfated, 3-linked galactan is an anticoagulant polisaccharide 2002
A sulphated fucan from the Laminaria abyssalis inhibits the human T cell lymphotropic virus type 1-induced syncytium formation in HeLa cells 2002
Struture and Anticoagulant Activity of Sulfated Galactans - Isolation of a unique sulfated galactan from the red algae Botryocladia occidentalis and comparison of its anticoagulant action with that of sulfated galactans from invertebrates 2000
Structure and Anticoagulant Activity of Sulfated Fucans - Comparison beteween the regular, repetitive, and linear fucans from echinoderms with the the more heterogeneous and branched polymers from brown algae. 1999
Searching for Alternatives to Heparin - The wide diversity of well-struturaly-defined sulfated fucans from marine invertebrates as a new source of anticoagulant and antithrombotic compounds 1999
Structure and Anticoagulant Activity of a Fucosylated Chondroitin Sulfate from Echinoderm 1996
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Structural features of the sulfated polysaccharides from the sea cucumber H. lentiginosa. In: 16th nuclear magnetic resonance users meeting 2017
Structural Characterization of Sulfated Polysaccharides Extracted from the Sea Cucumber Holothuria lentiginosa. 2017
Structural and Haemostatic Features of Pharmaceutical Heparins from Different Animal Sources: Challenges to Define Thresholds Separating Distinct Drugs 2017
Antimetastatic Potential of a Low Anticoagulant Heparin Derived from Bovine Intestinal Mucosa 2016
DEPOLYMERIZATION OF FUCOSYLATED CHONDROITIN SULFATE FROM SEA CUCUMBER USING HYDROGEN PEROXIDE AND COPPER IONS 2015
BOVINE INTESTINAL HEPARIN AND THERAPEUTIC USE BEYOND ANTICOAGULANT ACTIVITY 2015
Biosimilar Enoxaparins: Structure, Antithrombotic Activity and Side Effects 2014
DISCREPANCY AMONG DIFFERENT ASSAYS EMPLOYED TO TEST THE ANTICOAGULANT ACTIVITY OF PHARMACEUTICAL GRADE HEPARINS 2013
BIOCOMPARATIBILITY STUDY OF ENOXAPARINS IN CURRENT USE IN BRAZIL 2013
BOVINE AND PORCINE HEPARINS DIFFER IN THEIR STRUCTURE, ANTICOAGULANT ACTIVITY AND NEUTRALIZATION CURVES WITH PROTAMINE. 2013
Comparison of pharmacokinetics of unfractionated heparin and low molecular weight heparin after subcutaneous administration in rats 2012
Structure and Haemostatic Effects of Generic Versions of Enoxaparin Available for Clinical Use in Brazil 2012
How Similar are the Generic Versions of Enoxaparin Available for Clinical Use in Brazil to the Original Drug? 2011
Low Molecular Weight Heparin Quality Control in the Brazilian Market 2010
Practical implications of the differences observed between pharmaceutical grade heparins from bovine and porcine origin 2010
Neutralization of bovine and porcine intestinal heparins by protamine 2010
Mild Acid Hydrolysis of a Brown Algal Sulfated Galactofucan Produces a Venous Antithrombotic Derivative 2009
Beta- Glucans from Isolates of Botryosperia: Production, Chemical Characterization and Anticoagulant Activity 2009
Heparins from Bovine and Porcine Mucosas: Are They a Similar Drug? 2009
Sulfation and Anticoagulant Activity of Exopolysaccharides Produced by the Botryosphaeria Rhodina Mamb-05 Grown on Fructose 2009
Structure of Sulfated POlysaccharides from Sea Urchins: Biological Versus Physiological Activity 2009
Anticoagulant Activity of a Sulfated Galactan, Serpin-Independent Effect and Specific Interaction with Factor Xa 2009
Heparin Quality Control In the Brazilian Market: Implications in the Cardiovascular Surgery 2009
Serpin-Independent anticoagulant activity of a sulfated galactan 2008
Identification of a nonsense mutation causing antithrombin deficiency in a family with recurrent thrombosis 2008
Botryocladia occidentalis sulfated galactan inhibts haemostatic abnormalities induced by different venoms 2008
Serpin independent Anticoagulant and Antithrombotic Actions of Fucosylated Chondroitin Sulfate 2007
Structure and Anticoagulant Activity of the Products Obtained by Mild Acid Hydrolysis of the Sulfated Fucan from Laminaria abyssali 2007
STRUCTURE AND ANTICOAGULANT ACTIVITY OF THE PRODUCTS OBTAINED BY MILD ACID HYDROLYSIS OF THE SULFATED FUCAN FROM THE BROWN ALGA Laminaria abyssalis 2007
SERPIN-INDEPENDENT ANTICOAGULANT ACTIVITY OF SULFATED POLYSACCHARIDES FROM MARINE ORGANISMSi 2007
A SULFATED GALACTAN IS THE UNIQUE SULFATED POLYSACCHARIDE FOUND IN THE RED ALGA SOLIERIA FILIFORMIS 2007
Mild Acid Hydrolysis of Sulfated Fucan from the Brown Alga Laminaria abyssalis Yields Tailored Sulfated Oligosaccharides. 2006
Sufated Galactan and Heparin Differ in Their Preferred Pathway of Polysaccharide-accelerated Inactivation of Thrombin by Antithrombin 2006
A serpin independent inhibition of coagulation by sulfated polysaccharides from marine organisms 2006
Mild acid hidrolysis of sulfated fucan from the brown alga Laminaria abyssalis yelds tailored sulfated oligisaccharides 2006
Inhibition of platelet aggregation by a fucosilated chondroitin sulfate from a sea cucumber 2006
Calcium enhances sulfated galactan catalysis of the antithrombin-factor Xa inhibition reaction by a bridging mechanism 2005
The anticoagulant action of a sulfated galactan starts by its initial binding to thrombin instead of antithrombin 2005
Selective 2-desulfation of sulfated fucans by mild acid hydrolisis:an approach to prepare tailored oligossacharides 2005
Structure and anticoagulant activity of a sulfated fucan: selective removal of a 2-sulfate ester by mild acid hydrolysis, preparation of oligosaccharides and test of their anticoagulant activity 2004
Specifc desulfation of a sulfated fucan by mild acid hidrolysis with acid 2003
Antithrombin mediated anticoagulant action of sulfated galactans: preponderance of the bridging effect over the conformational change mechanism 2003
Sulfated polysaccharides from the male and female gonads of sea urchin 2002
Sulfated Oligosaccharides derived from a sulfated fucan of sea urchin Lytechinus variegatus 2002
Sulfated Oligosaccharides Obtained from Sulfated Fucans by Mild Acid Hidrolysis 2001
Anticoagulant Activity of Sulfated polysaccharides from Laminaria cichoriodes 2001
Anticoagulant Activity of a 2-O-Sulfated, 3-Linked Galactan 2001
Comparison Between the Anticoagulant Activity of Sulfated Fucans and Sulfated Galactans 2000
Sulfated Polysaccharides from Sea Urchins are Valuable Tools to Determine the Relationship Between Structure and Anticoagulant Activity 1999
Antithrombotic, Anticoagulant Activity and Platelet Aggregation of Sulfated Galactans Isolated from the Marine Macroalgae Botryocladia occidentalis 1999
In vivo Anticoagulant and Antithrombotic Activities of Ascidian Dermatan Sulfate Polymers and their Effect on Platelet Aggregation 1999
Structure and Anticoagulant Activity of Sulfated Fucans 1998
Sulfated Fucose Branches on a Fucosylated Chondroitin Sulfate from Echinoderm Account for its Anticoagulant Action 1996
Sulfated Fucose Branches on a Fucosylated Chondroitin Sulfate from Echinoderm Accounts for its Anticoagulant Action 1996
Anticoagulant Activity of the Sulfated Fucan And Sulfated Galactan from Marine Seaweed (L. brasiliensis and D. sanguinea) 1995
Comparative Study of Anticoagulant Activity of the Sulfated Fucans from Echinoderm and Marine Algae 1994
Comparative Study of Anticoagulant Activity of the Sulfated Polysaccharides from Marine Organisms 1994
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