Alberto Felix Antonio da Nobrega
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Microbiologia
Departamento:
Departamento de Imunologia/IM
Formação:
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Instituto Pasteur
| Pós-Doutorado | 1991 - 1993
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Doutorado | 1983 - 1990
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Centro Brasileiro de Pesquisas Físicas
Gravitação | Especialização | 1981 - 1981
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Pontifícia Universidade Católica do Rio de Janeiro
Matemática | Mestrado | 1981 - 1982
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Pontifícia Universidade Católica do Rio de Janeiro
Matemática | Graduação | 1977 - 1980
Laboratórios:
Nuvens de Palavras:
Artigos:
(43.66% artigos com DOI)
Titulo | DOI | Ano |
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Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts | 10.7554/elife.74636 | 2022 |
From a recombinant key antigen to an accurate, affordable serological test: Lessons learnt from COVID-19 for future pandemics | 10.1016/j.bej.2022.108537 | 2022 |
The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self | 10.1084/jem.20210580 | 2021 |
Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells | 10.1093/intimm/dxy011 | 2018 |
Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression | 10.3389/fimmu.2018.01173 | 2018 |
TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells | 10.3389/fimmu.2018.02281 | 2018 |
Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection | 10.7554/elife.30883 | 2017 |
CD60b: Enriching Neural Stem/Progenitor Cells from Rat Development into Adulthood | 10.1155/2017/5759490 | 2017 |
Enlarged colitogenic T cell population paradoxically supports colitis prevention through the B-lymphocyte-dependent peripheral generation of CD4+Foxp3+ Treg cells | 10.1038/srep28573 | 2016 |
The Global Self-Reactivity Profile of the Natural Antibody Repertoire Is Largely Independent of Germline DH Sequence | 10.3389/fimmu.2016.00296 | 2016 |
G-CSF-Induced Suppressor IL-10 + Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way | 10.4049/jimmunol.1502023 | 2016 |
The role of evolutionarily conserved germ-line D H sequence in B-1 cell development and natural antibody production | 10.1111/nyas.12808 | 2015 |
Plasticity of neutrophils reveals modulatory capacity | 10.1590/1414-431x20154524 | 2015 |
Enhanced renewal of regulatory t cells in relation to cd4 + conventional t lymphocytes in the peripheral compartment | 10.1111/imm.12555 | 2015 |
High levels of circulating triiodothyronine induce plasma cell differentiation | 10.1530/joe-13-0315 | 2014 |
IL-4 Regulates Bim Expression and Promotes B Cell Maturation in Synergy with BAFF Conferring Resistance to Cell Death at Negative Selection Checkpoints | 10.4049/jimmunol.1300749 | 2014 |
The link between antibodies to OxLDL and natural protection against pneumococci depends on DH gene conservation | 10.1084/jem.20121861 | 2013 |
New Insights from the Oyster Crassostrea rhizophorae on Bivalve Circulating Hemocytes | 10.1371/journal.pone.0057384 | 2013 |
The mannose receptor is expressed by olfactory ensheathing cells in the rat olfactory bulb | 10.1002/jnr.23285 | 2013 |
Neuroimmunoendocrine Regulation of the Prion Protein in Neutrophils | 10.1074/jbc.M112.394924 | 2012 |
A rapid and quantitative method for the evaluation of V gene usage, specificities and the clonal size of B cell repertoires | 10.1016/j.jim.2011.12.005 | 2012 |
Modulation of mature B cells in mice following treatment with ouabain | 10.1016/j.imbio.2011.03.002 | 2011 |
Genetic control of the B cell response to LPS: opposing effects in peritoneal versus splenic B cell populations | 10.1007/s00251-009-0404-9 | 2010 |
Impaired Innate Immunity in Tlr4?/? Mice but Preserved CD8+ T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice | 10.1371/journal.ppat.1000870 | 2010 |
Innate profiles of cytokines implicated on oral tolerance correlate with low- or high-suppression of humoral response | 10.1111/j.1365-2567.2010.03248.x | 2010 |
Intravenous immunoglobulin increases survival time in the acute phase of experimental Chagas disease | 10.1111/j.1365-3024.2010.01212.x | 2010 |
TLR4 Promotes B Cell Maturation: Independence and Cooperation with B Lymphocyte-Activating Factor | 10.4049/jimmunol.0903253 | 2010 |
Food allergy/hypersensitivity: Antigenicity or timing? | 10.1016/j.imbio.2008.09.007 | 2009 |
Selective blockade of lymphopoiesis induced by kalanchosine dimalate: inhibition of IL-7-dependent proliferation | 10.1189/jlb.0707441 | 2008 |
Inhibition of B cell development by kalanchosine dimalate | 10.1016/j.intimp.2008.01.028 | 2008 |
Diet selection in immunologically manipulated mice.Immunobiology | 10.1016/j.imbio.2007.08.001 | 2008 |
Susceptibility of neonatal T cells and adult thymocytes to peripheral | 2008 | |
Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi. | 2007 | |
Frequency of Natural Regulatory CD4+CD25+ T Lymphocytes Determines the Outcome of Tolerance across Fully Mismatched MHC Barrier through Linked Recognition of Self and Allogeneic Stimuli | 2006 | |
Genetic selection for resistance or susceptibility to oral tolerance impartscorrelation to both Immunoglobulin E level and mast cell number phenotypeswith a profound impact on the atopic potential of the individual | 2006 | |
Role of toll-like receptors (TLR) in B cell development: signaling through TL4 promotes B cell maturation and is inhibited by TLR2. | 2005 | |
Expression of functional TLR4 confers pro-inflammatory responsiveness to Trypanosoma Cruzi glicoinositolphospholipids and higher resistance to infection with T.cruzi | 2004 | |
Genetic selection for susceptibility to oral tolerance leads to a profound reduction of the acute inflammatory response. | 2004 | |
Is oral tolerance correlated with IgE levels and mast cell numbers? | 2004 | |
Natural antibody repertoire regeneration after massive ablation of the lymphoid system: robust selection mechanisms preserve antigen binding specificities | 2002 | |
Genetic diversity of Paenibacillus polymyxa populations isolated from the rhizosphere of four cultivars of maize (Zea mays) planted in Cerrado soil | 2002 | |
Fas ligand triggers pulmonary silicosis. | 2001 | |
Diversity of Paenibacillus polymixa strains isolated from the rhizosphere of maize planted in cerrado soil | 2000 | |
Functional diversity of natural IgM. | 1999 | |
Functional Diversity And Clonal Frequencies Of Reactivity In The Available Antibody Repertoire. | 1998 | |
Comparison Of Paenibacillus Azotofixans Strains Isolated From Rhizoplane, Rhizosphere And Non-Rizosphere Soil From Maize Planted In Two Different Brazilian Soils. | 1998 | |
Genetic control of natural antibody repertoires: I. IgH, MHC and TcR beta loci. | 1998 | |
Administration to mouse of endotoxin from gram-negative bacteria leads to activation and apoptosis of T lymphocytes | 1998 | |
Instability Of Natural Antibody Repertoire In Systemic Lupus Erythematosus Patients, Revealed By Multiparametric Analysis Of Serum Antibody Reactivities. | 1997 | |
The Repertoire Of Serum Igm In Normal Mice Is Largely Independent Of External Antigenic Contact. | 1997 | |
Characteristic Generated Alterations Of Autoantibody Patterns In Idiopathic Thrombocytopenic Purpura. | 1997 | |
Role Of Monocytes In The Up-Regulation Of The Early Activation Marker Cd69 On B And T Murine Lymphocytes Induced By Microbial Mitogens. | 1996 | |
Murine Acariasis. II. Immunological Disfunction And Evidence For Chronic Activation Of Th2 Lymphocytes. | 1996 | |
The Self-Reactive Antibody Repertoire Of Normal Human Serum Igm Is Acquired Early In Childhood And Remains Conserved Throughout Life. | 1996 | |
The Age Associated Increase In Autoreactive Immunoglobulins Reflects A Quantitative Increase In Specificities Detectable At Lower Concentrations In Young Mice. | 1996 | |
Invariance And Restriction Towards A Limited Set Of Self Antigens Characterize Neonatal Igm Antibody Repertoires And Prevail In Autoreactive Repertoires Of Healthy Adults. | 1995 | |
Studies On The T Cell Dependence Of Natural Igm And Igg Antibody Repertoires In Adult Mice. | 1995 | |
Negative Selection Of Multireactive B Cell Clones In Normal Adult Mice. | 1994 | |
Global Analysis Of Antibody Repertoires. I. An Immunoblot Method For The Quantitative Screening Of A Large Number Of Reactivities. | 1994 | |
Selectivity Of Recognition Of Variable (V) Regions Of Autoantibodies By Intravenous Immunoglobulin (Ivig). | 1994 | |
Observations On The Mode Of Action Of Normal Immunoglobulin At High Doses. | 1994 | |
Analysis Of Natural And Disease-Associated Autoantibody Repertoires: Anti-Endothelial Cell Igg Autoantibody Activity In The Serum Of Healthy Individuals And Patients With Systemic Lupus Erythematosus. | 1994 | |
Global Analysis Of Antibody Repertoires. II. Evidence For Specificity, Self-Selection And The Immunological | 1993 | |
Comparative analysis of syngeneic and allogeneic mixed lymphocyte reaction of naturally activated and resting T cells | 1992 | |
Differential activation requirements for naturally activated and resting T cells | 1990 | |
Do self reactive anti-heart T lymphocytes expand in T Cruzi infected hosts? | 1988 | |
Stage specific distinctions in Potassium channel blocker control of T lymphocyte activation | 1988 | |
Modulation of murine T lymphocyte activation by neurotransmitters adenosine and dopamine | 1987 | |
Purinergic Modulation Of T Lymphocyte Activation : Differential Susceptibility Of Distinct Activation Steps And Correlation With Cyclic Monophosphate Accumulation. | 1986 | |
Evidence for heterogeneities within K+ channel control of T cell activation | 1986 | |
Analysis of isolated and combined effects of calcium ionophore and phorbol ester on T lymphocyte activation | 1986 |
Eventos:
(0.00% eventos com DOI)