Alberto Felix Antonio da Nobrega

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Microbiologia

Departamento:

Departamento de Imunologia/IM

ORCID:

não disponível no Lattes


Formação:
  • Instituto Pasteur

    | Pós-Doutorado | 1991 - 1993
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1983 - 1990
  • Centro Brasileiro de Pesquisas Físicas

    Gravitação | Especialização | 1981 - 1981
  • Pontifícia Universidade Católica do Rio de Janeiro

    Matemática | Mestrado | 1981 - 1982
  • Pontifícia Universidade Católica do Rio de Janeiro

    Matemática | Graduação | 1977 - 1980
Laboratórios:
Nuvens de Palavras:
Artigos:

(43.66% artigos com DOI)

Titulo DOI Ano
Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts 10.7554/elife.74636 2022
From a recombinant key antigen to an accurate, affordable serological test: Lessons learnt from COVID-19 for future pandemics 10.1016/j.bej.2022.108537 2022
The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self 10.1084/jem.20210580 2021
Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells 10.1093/intimm/dxy011 2018
Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression 10.3389/fimmu.2018.01173 2018
TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells 10.3389/fimmu.2018.02281 2018
Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection 10.7554/elife.30883 2017
CD60b: Enriching Neural Stem/Progenitor Cells from Rat Development into Adulthood 10.1155/2017/5759490 2017
Enlarged colitogenic T cell population paradoxically supports colitis prevention through the B-lymphocyte-dependent peripheral generation of CD4+Foxp3+ Treg cells 10.1038/srep28573 2016
The Global Self-Reactivity Profile of the Natural Antibody Repertoire Is Largely Independent of Germline DH Sequence 10.3389/fimmu.2016.00296 2016
G-CSF-Induced Suppressor IL-10 + Neutrophils Promote Regulatory T Cells That Inhibit Graft-Versus-Host Disease in a Long-Lasting and Specific Way 10.4049/jimmunol.1502023 2016
The role of evolutionarily conserved germ-line D H sequence in B-1 cell development and natural antibody production 10.1111/nyas.12808 2015
Plasticity of neutrophils reveals modulatory capacity 10.1590/1414-431x20154524 2015
Enhanced renewal of regulatory t cells in relation to cd4 + conventional t lymphocytes in the peripheral compartment 10.1111/imm.12555 2015
High levels of circulating triiodothyronine induce plasma cell differentiation 10.1530/joe-13-0315 2014
IL-4 Regulates Bim Expression and Promotes B Cell Maturation in Synergy with BAFF Conferring Resistance to Cell Death at Negative Selection Checkpoints 10.4049/jimmunol.1300749 2014
The link between antibodies to OxLDL and natural protection against pneumococci depends on DH gene conservation 10.1084/jem.20121861 2013
New Insights from the Oyster Crassostrea rhizophorae on Bivalve Circulating Hemocytes 10.1371/journal.pone.0057384 2013
The mannose receptor is expressed by olfactory ensheathing cells in the rat olfactory bulb 10.1002/jnr.23285 2013
Neuroimmunoendocrine Regulation of the Prion Protein in Neutrophils 10.1074/jbc.M112.394924 2012
A rapid and quantitative method for the evaluation of V gene usage, specificities and the clonal size of B cell repertoires 10.1016/j.jim.2011.12.005 2012
Modulation of mature B cells in mice following treatment with ouabain 10.1016/j.imbio.2011.03.002 2011
Genetic control of the B cell response to LPS: opposing effects in peritoneal versus splenic B cell populations 10.1007/s00251-009-0404-9 2010
Impaired Innate Immunity in Tlr4?/? Mice but Preserved CD8+ T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice 10.1371/journal.ppat.1000870 2010
Innate profiles of cytokines implicated on oral tolerance correlate with low- or high-suppression of humoral response 10.1111/j.1365-2567.2010.03248.x 2010
Intravenous immunoglobulin increases survival time in the acute phase of experimental Chagas disease 10.1111/j.1365-3024.2010.01212.x 2010
TLR4 Promotes B Cell Maturation: Independence and Cooperation with B Lymphocyte-Activating Factor 10.4049/jimmunol.0903253 2010
Food allergy/hypersensitivity: Antigenicity or timing? 10.1016/j.imbio.2008.09.007 2009
Selective blockade of lymphopoiesis induced by kalanchosine dimalate: inhibition of IL-7-dependent proliferation 10.1189/jlb.0707441 2008
Inhibition of B cell development by kalanchosine dimalate 10.1016/j.intimp.2008.01.028 2008
Diet selection in immunologically manipulated mice.Immunobiology 10.1016/j.imbio.2007.08.001 2008
Susceptibility of neonatal T cells and adult thymocytes to peripheral 2008
Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi. 2007
Frequency of Natural Regulatory CD4+CD25+ T Lymphocytes Determines the Outcome of Tolerance across Fully Mismatched MHC Barrier through Linked Recognition of Self and Allogeneic Stimuli 2006
Genetic selection for resistance or susceptibility to oral tolerance impartscorrelation to both Immunoglobulin E level and mast cell number phenotypeswith a profound impact on the atopic potential of the individual 2006
Role of toll-like receptors (TLR) in B cell development: signaling through TL4 promotes B cell maturation and is inhibited by TLR2. 2005
Expression of functional TLR4 confers pro-inflammatory responsiveness to Trypanosoma Cruzi glicoinositolphospholipids and higher resistance to infection with T.cruzi 2004
Genetic selection for susceptibility to oral tolerance leads to a profound reduction of the acute inflammatory response. 2004
Is oral tolerance correlated with IgE levels and mast cell numbers? 2004
Natural antibody repertoire regeneration after massive ablation of the lymphoid system: robust selection mechanisms preserve antigen binding specificities 2002
Genetic diversity of Paenibacillus polymyxa populations isolated from the rhizosphere of four cultivars of maize (Zea mays) planted in Cerrado soil 2002
Fas ligand triggers pulmonary silicosis. 2001
Diversity of Paenibacillus polymixa strains isolated from the rhizosphere of maize planted in cerrado soil 2000
Functional diversity of natural IgM. 1999
Functional Diversity And Clonal Frequencies Of Reactivity In The Available Antibody Repertoire. 1998
Comparison Of Paenibacillus Azotofixans Strains Isolated From Rhizoplane, Rhizosphere And Non-Rizosphere Soil From Maize Planted In Two Different Brazilian Soils. 1998
Genetic control of natural antibody repertoires: I. IgH, MHC and TcR beta loci. 1998
Administration to mouse of endotoxin from gram-negative bacteria leads to activation and apoptosis of T lymphocytes 1998
Instability Of Natural Antibody Repertoire In Systemic Lupus Erythematosus Patients, Revealed By Multiparametric Analysis Of Serum Antibody Reactivities. 1997
The Repertoire Of Serum Igm In Normal Mice Is Largely Independent Of External Antigenic Contact. 1997
Characteristic Generated Alterations Of Autoantibody Patterns In Idiopathic Thrombocytopenic Purpura. 1997
Role Of Monocytes In The Up-Regulation Of The Early Activation Marker Cd69 On B And T Murine Lymphocytes Induced By Microbial Mitogens. 1996
Murine Acariasis. II. Immunological Disfunction And Evidence For Chronic Activation Of Th2 Lymphocytes. 1996
The Self-Reactive Antibody Repertoire Of Normal Human Serum Igm Is Acquired Early In Childhood And Remains Conserved Throughout Life. 1996
The Age Associated Increase In Autoreactive Immunoglobulins Reflects A Quantitative Increase In Specificities Detectable At Lower Concentrations In Young Mice. 1996
Invariance And Restriction Towards A Limited Set Of Self Antigens Characterize Neonatal Igm Antibody Repertoires And Prevail In Autoreactive Repertoires Of Healthy Adults. 1995
Studies On The T Cell Dependence Of Natural Igm And Igg Antibody Repertoires In Adult Mice. 1995
Negative Selection Of Multireactive B Cell Clones In Normal Adult Mice. 1994
Global Analysis Of Antibody Repertoires. I. An Immunoblot Method For The Quantitative Screening Of A Large Number Of Reactivities. 1994
Selectivity Of Recognition Of Variable (V) Regions Of Autoantibodies By Intravenous Immunoglobulin (Ivig). 1994
Observations On The Mode Of Action Of Normal Immunoglobulin At High Doses. 1994
Analysis Of Natural And Disease-Associated Autoantibody Repertoires: Anti-Endothelial Cell Igg Autoantibody Activity In The Serum Of Healthy Individuals And Patients With Systemic Lupus Erythematosus. 1994
Global Analysis Of Antibody Repertoires. II. Evidence For Specificity, Self-Selection And The Immunological 1993
Comparative analysis of syngeneic and allogeneic mixed lymphocyte reaction of naturally activated and resting T cells 1992
Differential activation requirements for naturally activated and resting T cells 1990
Do self reactive anti-heart T lymphocytes expand in T Cruzi infected hosts? 1988
Stage specific distinctions in Potassium channel blocker control of T lymphocyte activation 1988
Modulation of murine T lymphocyte activation by neurotransmitters adenosine and dopamine 1987
Purinergic Modulation Of T Lymphocyte Activation : Differential Susceptibility Of Distinct Activation Steps And Correlation With Cyclic Monophosphate Accumulation. 1986
Evidence for heterogeneities within K+ channel control of T cell activation 1986
Analysis of isolated and combined effects of calcium ionophore and phorbol ester on T lymphocyte activation 1986
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Analysis of serum IgM repertoire of mice with genetic restriction of VDJ rearranjement 2006
Kalanchoe brasiliensis (Saião) extract promotes blockade of lymphopoiesis in vivo 2006
Global analysis of antibody repertoire in murine model of Chagas Disease 1998
Ontogeny of IgM repertoire in the C57B1/6 mouse 1998
Ontogenia do repertório de IgM sérica no camundongo C57B1/6 1998
Studies On The Specificities Of Igm Repertoire: Clonality, Selection And Tissue Specific Variability. 1997
Studies On The Diversity And Heterogeneity Of Antibody Repertoire. 1996
Antibody Repertoires On Health And Disease. 1996
Studies On The Diversity And Heterogeneity Of Antibody Repertoire. 1995
Studies On The Diversity And Heterogeneity Of Antibody Repertoire: Clonality, Selection And Tissue Specific Variability. 1995
Natural Antibodies. 1994
Análise Global do Repertório de Anticorpos. 1994
Diferenças na capacidade secretória e proliferativa de interleucinas 2 e 3, das populações linfocitárias naturalmente ativadas e em repouso 1989
Efeito da ciclofosfamida no calazar experimental: ação das células supressoras. 1989
Resting and naturally activated T cells differs in in vitro proliferative and secretory responses 1989
Evidências que a ausencia de proliferação de células T autoreativas é um fenomeno ativo 1988
Effects of the neurotransmitter Dopamine on T lymphocyte activation 1986
T lymphocyte activation: an early Ca2+ influx is critical for the induction of IL-2 responsivness 1985
Publicações:
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