Marina Amaral Alves
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências Matemáticas e da Natureza
Unidade:
Instituto de Química
Departamento:
Seção de Atividades Gerenciais IQ/CCMN
Formação:
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University of Turku
| Pós-Doutorado | 2019 - 2021
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Universidade Federal do Rio de Janeiro
Química | Doutorado | 2012 - 2017
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Universidade Federal do Rio de Janeiro
Habilitação Farmacêutico Industrial | Especialização | 2010 - 2015
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Universidade Federal do Rio de Janeiro
Química | Mestrado | 2010 - 2012
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Universidade Federal do Rio de Janeiro
Farmácia | Graduação | 2006 - 2010
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:
(100.00% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Synthesis, in silico, and in vitro Evaluation of 7-chloro-quinolines Designed as Myeloperoxidase Inhibitors | 10.1016/j.molstruc.2024.138528 | 2024 |
| Synthesis and pharmacological evaluation of novel N-aryl-cinnamoyl-hydrazone hybrids designed as neuroprotective agents for the treatment of Parkinson?s disease | 10.1016/j.bioorg.2024.107587 | 2024 |
| Critical Factors in Sample Collection and Preparation for Clinical Metabolomics of Underexplored Biological Specimens | 10.3390/metabo14010036 | 2024 |
| Dynamics of the Lipidome in a Colon Simulator | 10.3390/metabo13030355 | 2023 |
| Chemical Profile by UPLC-HRMS and Antifungal and Antioxidant Activity of Marine Macroalgae Dictyota menstrualis | 10.21577/1984-6835.20230044 | 2023 |
| Regio- and Chemoselective Synthesis of Polyaryl Flavones by Combination of C-O/C-H Activation and Suzuki-Miyaura Cross Coupling Reactions | 10.1016/j.molstruc.2023.137067 | 2023 |
| Neotropical mustelids: fecal metabolome diversity and its potential for taxonomic discrimination | 10.1111/1749-4877.12645 | 2022 |
| Pre-clinical evaluation of LASSBio-1491: From in vitro pharmacokinetic study to in vivo leishmanicidal activity | 10.1371/journal.pone.0269447 | 2022 |
| Dysregulation of secondary bile acid metabolism precedes islet autoimmunity and type 1 diabetes | 10.1016/j.xcrm.2022.100762 | 2022 |
| Synthesis and biological evaluation of 4-hydroxy-methylpiperidinyl-N-benzyl-acylarylhydrazone hybrids designed as novel multifunctional drug candidates for Alzheimer?s disease | 10.1016/j.bmc.2022.116952 | 2022 |
| Metabology: Analysis of metabolomics data using community ecology tools | 10.1016/j.aca.2022.340469 | 2022 |
| Linking Gut Microbiome and Lipid Metabolism: Moving beyond Associations | 10.3390/metabo11010055 | 2021 |
| Systems biology approaches to study lipidomes in health and disease | 10.1016/j.bbalip.2020.158857 | 2021 |
| A Systematic Pipeline to Enhance the Fecal Metabolome Coverage by LC-HRMS | 10.21577/0103-5053.20210042 | 2021 |
| Monocyclic Nitro-heteroaryl Nitrones with Dual Mechanism of Activation: Synthesis and Antileishmanial Activity | 10.1021/acsmedchemlett.1c00193 | 2021 |
| Quantitative genome-scale metabolic modeling of human CD4+ T cell differentiation reveals subset-specific regulation of glycosphingolipid pathways | 10.1016/j.celrep.2021.109973 | 2021 |
| Design, Synthesis and Pharmacological Evaluation of First¿in¿Class Multitarget N¿Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors | 10.1002/cmdc.201900716 | 2020 |
| Structure-Property Relationship Studies of 3-Acyl-Substituted Furans: The Serendipitous Identification and Characterization of a New Non-Classical Hydrogen Bond Donor Moiety | 10.1039/d0nj01598a | 2020 |
| Carbamoyl- N-aryl-imine-urea: a new framework to obtain a putative leishmanicidal drug-candidate | 10.1039/d0ra00287a | 2020 |
| New Leishmania donovani nucleoside hydrolase inhibitors from Brazilian flora | 10.1039/c9ra02382h | 2019 |
| Semicarbazone derivatives as promising therapeutic alternatives in leishmaniasis | 10.1016/j.exppara.2019.04.003 | 2019 |
| Homologation: A versatile molecular modification strategy to drug discovery | 10.2174/1568026619666190808145235 | 2019 |
| Synthesis and in silico and in vitro evaluation of trimethoxy-benzamides designed as anti-prion derivatives | 10.1007/s00044-019-02441-2 | 2019 |
| Synthesis, Aqueous Solubility, Metabolic Stability and Pharmacological Profile of Simplified Urea Derivatives | 10.2174/1570180814666171012155204 | 2018 |
| Discovery of naphthyl- N -acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity | 10.1111/cbdd.13085 | 2018 |
| Leishmanicidal candidate LASSBio-1736, a cysteine protease inhibitor with favorable pharmacokinetics: low clearance and good distribution | 10.1080/00498254.2017.1405465 | 2017 |
| Theoretical and Experimental Characterization of 1,4-N---S σ-hole Intramolecular Interactions in Bioactive N-Acylhydrazone Derivatives | 10.1039/c7nj03543h | 2017 |
| Non-competitive inhibitor of nucleoside hydrolase from Leishmania donovani identified by fragment-based drug discovery | 10.1039/C6RA15143D | 2016 |
| Simple HPLC-UV for the quantification of a new leishmanicidal candidate ( E )-1-4(trifluoromethyl) benzylidene)-5-(2-4-dichlorozoyl) carbonylhydrazine (LASSBio-1736) in rat plasma for pharmacokinetics assessment | 10.1002/bmc.3646 | 2016 |
| Design, synthesis and in vitro trypanocidal and leishmanicidal activities of novel semicarbazone derivatives | 10.1016/j.ejmech.2015.05.046 | 2015 |
| 3-Aminothiophene-2-Acylhydrazones: Non-Toxic, Analgesic and Anti-Inflammatory Lead-Candidates | 10.3390/molecules19068456 | 2014 |
| New oxidovanadium(IV) N-acylhydrazone complexes: Promising antileishmanial and antitrypanosomal agents | 10.1016/j.ejmech.2012.12.036 | 2013 |
| Synthesis, Biological Evaluation, and Structure-activity Relationship of Clonazepam, Meclonazepam, and 1,4-Benzodiazepine Compounds with Schistosomicidal Activity | 10.1111/j.1747-0285.2012.01354.x | 2012 |
| Analgesic and Anti-Inflammatory Activities of Salicylaldehyde 2-Chlorobenzoyl Hydrazone (H2LASSBio-466), Salicylaldehyde 4-Chlorobenzoyl Hydrazone (H2LASSBio-1064) and Their Zinc(II) Complexes | 10.3390/molecules16086902 | 2011 |
Eventos:
Nenhum evento cadastrado