Leonardo Nimrichter
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Microbiologia
Departamento:
Departamento de Microbiologia Geral/IM
Formação:
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Universidade Federal de São Paulo
| Pós-Doutorado | 2005 - 2006
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Universidade de São Paulo
| Pós-Doutorado | 2004 - 2005
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Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Doutorado | 2000 - 2004
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Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Mestrado | 1997 - 2000
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Universidade Federal do Rio de Janeiro
Aperfeiçoamento Em Microbiologia e Imunologia | Especialização | 1996 - 1997
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Universidade Federal do Rio de Janeiro
Farmácia | Graduação | 1992 - 1995
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:
(98.26% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Cyclosporine Affects the Main Virulence Factors of Cryptococcus neoformans In Vitro | 10.3390/jof9040487 | 2023 |
| Professor Luiz R. Travassos and the study of surface structures of fungal pathogens | 10.1007/s42770-023-00916-4 | 2023 |
| Unveiling the Morphostructural Plasticity of Zoonotic Sporotrichosis Fungal Strains: Possible Implications for Sporothrix brasiliensis Virulence and Pathogenicity | 10.3390/jof9070701 | 2023 |
| A tribute to a man of science: lessons from Professor Luiz R. Travassos (1938-2020) | 10.1007/s42770-023-00908-4 | 2023 |
| Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans | 10.1128/mbio.00870-23 | 2023 |
| Traversing the Cell Wall: The Chitinolytic Activity of Histoplasma capsulatum Extracellular Vesicles Facilitates Their Release | 10.3390/jof9111052 | 2023 |
| Micro- and nanoparticles as platforms for the treatment of fungal infections: present and future perspectives | 10.2217/fmb-2023-0079 | 2023 |
| From fundamental biology to the search for innovation: the story of fungal extracellular vesicles | 10.1016/j.ejcb.2022.151205 | 2022 |
| Extracellular Vesicles Regulate Biofilm Formation and Yeast-to-Hypha Differentiation in Candida albicans | 10.1128/mbio.00301-22 | 2022 |
| Silver Chitosan Nanocomposites are Effective to Combat Sporotrichosis | 10.3389/fnano.2022.857681 | 2022 |
| Recognition of Cell Wall Mannosylated Components as a Conserved Feature for Fungal Entrance, Adaptation and Survival Within Trophozoites of Acanthamoeba castellanii and Murine Macrophages | 10.3389/fcimb.2022.858979 | 2022 |
| Extracellular Vesicle Formation in Cryptococcus deuterogattii Impacts Fungal Virulence and Requires the NOP16 Gene | 10.1128/iai.00232-22 | 2022 |
| Editorial: Emerging roles of extracellular vesicles in immunomodulation during host-pathogen interactions | 10.3389/fimmu.2022.958179 | 2022 |
| Vaccination with Live or Heat-Killed Aspergillus fumigatus - sglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis | 10.1128/mbio.02328-22 | 2022 |
| In vitro and in vivo efficacies of Dectin-1-Fc(IgG)(s) fusion proteins against invasive fungal infections | 10.1093/mmy/myac050 | 2022 |
| Melanization of Candida auris Is Associated with Alteration of Extracellular pH | 10.3390/jof8101068 | 2022 |
| Pathogenicity & Virulence of Histoplasma capsulatum - a multifaceted organism adapted to intracellular environments | 10.1080/21505594.2022.2137987 | 2022 |
| Dexamethasone and methylprednisolone promote cell proliferation, capsule enlargement, and in vivo dissemination of C. neoformans | 10.3389/ffunb.2021.643537 | 2021 |
| Histoplasma capsulatum glycans from distinct genotypes share structural and serological similarities to Cryptococcus neoformans glucuronoxylomannan | 10.3389/fcimb.2020.565571 | 2021 |
| Comparative Molecular and Immunoregulatory Analysis of Extracellular Vesicles from Candida albicans and Candida auris | 10.1128/msystems.00822-21 | 2021 |
| Host cell membrane microdomains and fungal infection | 10.1111/cmi.13385 | 2021 |
| Cryptococcus extracellular vesicles properties and their use as vaccine platforms | 10.1002/jev2.12129 | 2021 |
| The paradoxical and still obscure properties of fungal extracellular vesicles | 10.1016/j.molimm.2021.04.009 | 2021 |
| Silver chitosan nanocomposites as a potential treatment for superficial candidiasis | 10.1093/mmy/myab028 | 2021 |
| Omics Approaches for Understanding Biogenesis, Composition and Functions of Fungal Extracellular Vesicles | 10.3389/fgene.2021.648524 | 2021 |
| Small Molecule Analysis of Extracellular Vesicles Produced by Cryptococcus gattii: Identification of a Tripeptide Controlling Cryptococcal Infection in an Invertebrate Host Model | 10.3389/fimmu.2021.654574 | 2021 |
| Antifungal activity of Acylhydrazone derivatives against Sporothrix spp. | 10.1128/aac.02593-20 | 2021 |
| X-linked immunodeficient (XID) mice exhibit high susceptibility to Cryptococcus gattii infection | 10.1038/s41598-021-97041-9 | 2021 |
| Protective effect of fungal extracellular vesicles against murine candidiasis. | 10.1111/cmi.13238 | 2020 |
| Media Matters! Alterations in the loading and release of |
10.1111/cmi.13217 | 2020 |
| Protective Efficacy of Lectin-Fc(IgG) Fusion Proteins In Vitro and in a Pulmonary Aspergillosis In Vivo Model | 10.3390/jof6040250 | 2020 |
| Characterization of Extracellular Vesicles Produced by Aspergillus fumigatus Protoplasts | 10.1128/msphere.00476-20 | 2020 |
| Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model | 10.1128/mbio.02909-18 | 2019 |
| A Novel Protocol for the Isolation of Fungal Extracellular Vesicles Reveals the Participation of a Putative Scramblase in Polysaccharide Export and Capsule Construction in Cryptococcus gattii | 10.1128/msphere.00080-19 | 2019 |
| Multi-omics Signature of , an Emerging and Multidrug-Resistant Pathogen | 10.1128/mSystems.00257-19 | 2019 |
| Role of lipid transporters in fungal physiology and pathogenicity | 10.1016/j.csbj.2019.09.001 | 2019 |
| Investigation of Candida parapsilosis virulence regulatory factors during host-pathogen interaction | 10.1038/s41598-018-19453-4 | 2018 |
| Fungal extracellular vesicles: modulating host-pathogen interactions by both the fungus and the host | 10.1016/j.micinf.2018.01.011 | 2018 |
| Extracellular vesicles and vesicle-free secretome of the protozoa Acanthamoeba castellanii under homeostasis and nutritional stress and their damaging potential to host cells | 10.1080/21505594.2018.1451184 | 2018 |
| Concentration-dependent protein loading of extracellular vesicles released by Histoplasma capsulatum after antibody treatment and its modulatory action upon macrophages | 10.1038/s41598-018-25665-5 | 2018 |
| Host membrane glycosphingolipids and lipid microdomains facilitate Histoplasma capsulatum internalization by macrophages. | 10.1111/cmi.12976 | 2018 |
| A glucuronoxylomannan-like glycan produced by Trichosporon mucoides | 10.1016/j.fgb.2018.09.009 | 2018 |
| Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | 10.1080/20013078.2018.1535750 | 2018 |
| Characterization of the antifungal functions of a WGA-Fc (IgG2a) fusion protein binding to cell wall chitin oligomers | 10.1038/s41598-017-12540-y | 2017 |
| What Is New? Recent Knowledge on Fungal Extracellular Vesicles | 10.1007/s12281-017-0293-6 | 2017 |
| Antibody Binding Alters the Characteristics and Contents of Extracellular Vesicles Released by Histoplasma capsulatum | 10.1128/msphere.00085-15 | 2016 |
| Potential Roles of Fungal Extracellular Vesicles during Infection | 10.1128/msphere.00099-16 | 2016 |
| Extracellular Vesicle-Associated Transitory Cell Wall Components and Their Impact on the Interaction of Fungi with Host Cells | 10.3389/fmicb.2016.01034 | 2016 |
| The putative autophagy regulator Atg7 affects the physiology and pathogenic mechanisms of Cryptococcus neoformans | 10.2217/fmb-2016-0090 | 2016 |
| The benefits of scientific mobility and international collaboration | 10.1093/femsle/fnw247 | 2016 |
| Enhanced virulence of Histoplasma capsulatum through transfer and surface incorporation of glycans from Cryptococcus neoformans during co-infection | 10.1038/srep21765 | 2016 |
| Extracellular vesicle-mediated export of fungal RNA | 10.1038/srep07763 | 2015 |
| Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids | 10.1128/mbio.00647-15 | 2015 |
| Probiotic Saccharomyces cerevisiae strains as biotherapeutic tools: is there room for improvement? | 10.1007/s00253-015-6776-x | 2015 |
| Traveling into Outer Space: Unanswered Questions about Fungal Extracellular Vesicles | 10.1371/journal.ppat.1005240 | 2015 |
| The Einstein-Brazil Fogarty: A decade of synergy | 10.1590/s1517-838246420140975 | 2015 |
| Synthesis and Biological Properties of Fungal Glucosylceramide | 10.1371/journal.ppat.1003832 | 2014 |
| Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans | 10.1111/cmi.12374 | 2014 |
| Definition of Molecular Determinants of Prostate Cancer Cell Bone Extravasation | 10.1158/0008-5472.CAN-12-3264 | 2013 |
| Vesicular mechanisms of traffic of fungal molecules to the extracellular space | 10.1016/j.mib.2013.04.002 | 2013 |
| Binding of the wheat germ lectin to Cryptococcus neoformans chitooligomers affects multiple mechanisms required for fungal pathogenesis | 10.1016/j.fgb.2013.04.005 | 2013 |
| Use of a Stainless Steel Washer Platform to Study Acinetobacter baumannii Adhesion and Biofilm Formation on Abiotic Surfaces | 10.1099/mic.0.068825-0 | 2013 |
| The impact of proteomics on the understanding of functions and biogenesis of fungal extracellular vesicles | 10.1016/j.jprot.2013.04.001 | 2013 |
| Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells | 10.1371/journal.pone.0029561 | 2012 |
| The plant defensin RsAFP2 induces cell wall stress, septin mislocalization and accumulation of ceramides in Candida albicans | 10.1111/j.1365-2958.2012.08017.x | 2012 |
| Chitin-like molecules associate with Cryptococcus neoformans glucuronoxylomannan to form a glycan complex with previously unknown properties | 10.1128/EC.00001-12 | 2012 |
| A Paracoccidioides brasiliensis glycan shares serologic and functional properties with cryptococcal glucuronoxylomannan | 10.1016/j.fgb.2012.09.002 | 2012 |
| Inhibition of Candida parapsilosis Fatty Acid Synthase (Fas2) Induces Mitochondrial Cell Death in Serum | 10.1371/journal.ppat.1002879 | 2012 |
| In good company: association between fungal glycans generates molecular complexes with unique functions | 10.3389/fmicb.2012.00249 | 2012 |
| Antibody Binding to Cryptococcus neoformans Impairs Budding by Altering Capsular Mechanical Properties | 10.4049/jimmunol.1202324 | 2012 |
| The GATA-type transcriptional activator Gat1 regulates nitrogen uptake and metabolism in the human pathogen Cryptococcus neoformans | 10.1016/j.fgb.2010.07.011 | 2011 |
| Agglutination of Histoplasma capsulatum by IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions | 10.1128/IAI.00673-10 | 2011 |
| Glucuronoxylomannan from Cryptococcus neoformans down-regulates the enzyme 6-phosphofructo-1-kinase of macrophages | 10.1074/jbc.M110.177030 | 2011 |
| Gangliosides expressed on breast cancer cells are E-selectin ligands | 10.1016/j.bbrc.2011.02.061 | 2011 |
| Role for Golgi reassembly and stacking protein (GRASP) in polysaccharide secretion and fungal virulence | 10.1111/j.1365-2958.2011.07686.x | 2011 |
| Histoplasma capsulatum Heat-Shock 60 Orchestrates the Adaptation of the Fungus to Temperature Stress | 10.1371/journal.pone.0014660 | 2011 |
| Fungal Polysaccharides: Biological Activity Beyond the Usual Structural Properties | 10.3389/fmicb.2011.00171 | 2011 |
| CHRONOLOGICAL AGING IS ASSOCIATED WITH BIOPHYSICAL AND CHEMICAL CHANGES IN THE CAPSULE OF CRYPTOCOCCUS NEOFORMANS | 10.1128/IAI.05789-11 | 2011 |
| Fungal Glucosylceramides: From Structural Components to Biologically Active Targets of New Antimicrobials | 10.3389/fmicb.2011.00212 | 2011 |
| Vesicular transport systems in fungi | 10.2217/fmb.11.112 | 2011 |
| Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo | 10.1111/j.1462-5822.2010.01430.x | 2010 |
| Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions | 10.1128/IAI.01171-09 | 2010 |
| Characterization of Yeast Extracellular Vesicles: Evidence for the Participation of Different Pathways of Cellular Traffic in Vesicle Biogenesis | 10.1371/journal.pone.0011113 | 2010 |
| Immunomodulatory effects of serotype B glucuronoxylomannan from Cryptococcus gattii correlate with polysaccharide diameter | 10.1128/IAI.00111-10 | 2010 |
| The Vacuolar Ca2+ Exchanger Vcx1 Is Involved in Calcineurin-Dependent Ca2+ Tolerance and Virulence in Cryptococcus neoformans | 10.1128/EC.00114-10 | 2010 |
| Biochemical characterization of an ecto-ATP diphosphohydrolase activity in Candida parapsilosis?and its possible role in adenosine acquisition and pathogenesis | 10.1111/j.1567-1364.2010.00641.x | 2010 |
| Biogenesis of extracellular vesicles in yeast: Many questions with few answers | 10.4161/cib.3.6.12756 | 2010 |
| Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules | 10.1073/pnas.0808995106 | 2009 |
| Structural and functional properties of the Trichosporon asahii glucuronoxylomannan | 10.1016/j.fgb.2009.03.003 | 2009 |
| The still obscure attributes of cryptococcal glucuronoxylomannan | 10.1080/13693780902788621 | 2009 |
| A role for chitin and chitooligomers in the capsular architecture of Cryptococcus neoformans. | 10.1128/EC.00142-09 | 2009 |
| The Elastic Properties of the Cryptococcus neoformans Capsule | 10.1016/j.bpj.2009.04.043 | 2009 |
| Cryptococcus neoformans cryoimmunoelectronmicroscopy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan | 10.1016/j.fgb.2009.09.001 | 2009 |
| Identification of iGb3 and iGb4 in melanoma B16F10-Nex2 cells and the iNKT cell-mediated antitumor effect of dendritic cells primed with iGb3 | 10.1186/1476-4598-8-116 | 2009 |
| Effective Topical Treatment of Subcutaneous Murine B16F10-Nex2 Melanoma By the Antimicrobial Peptide Gomesin | 10.1593/neo.07885 | 2008 |
| E-selectin receptors on human leukocytes | 10.1182/blood-2008-04-149641 | 2008 |
| In Vitro Activity of the Antifungal Plant Defensin RsAFP2 against Candida Isolates and Its In Vivo Efficacy in Prophylactic Murine Models of Candidiasis | 10.1128/AAC.00448-08 | 2008 |
| Vesicular Trans-Cell Wall Transport in Fungi: A Mechanism for the Delivery of Virulence-Associated Macromolecules? | 2008 | |
| An ectophosphatase activity in Candida parapsilosis influences the interaction of fungi with epithelial cells | 10.1111/j.1567-1364.2007.00223.x | 2007 |
| Binding of Glucuronoxylomannan to the CD14 Receptor in Human A549 Alveolar Cells Induces Interleukin-8 Production | 10.1128/CVI.00296-06 | 2007 |
| Biology and pathogenesis of Fonsecaea pedrosoi, the major etiologic agent of chromoblastomycosis | 10.1111/j.1574-6976.2007.00077.x | 2007 |
| Self-Aggregation of Cryptococcus neoformans Capsular Glucuronoxylomannan Is Dependent on Divalent Cations | 10.1128/EC.00122-07 | 2007 |
| Gomesin, a peptide produced by the spider Acanthoscurria gomesiana, is a potent anticryptococcal agent that acts in synergism with fluconazole | 10.1111/j.1574-6968.2007.00850.x | 2007 |
| Cryptococcus neoformans Capsular Polysaccharide and Exopolysaccharide Fractions Manifest Physical, Chemical, and Antigenic Differences | 10.1128/EC.00378-07 | 2007 |
| Extracellular Vesicles Produced by Cryptococcus neoformans Contain Protein Components Associated with Virulence | 10.1128/EC.00370-07 | 2007 |
| Monoclonal Antibody to Fungal Glucosylceramide Protects Mice against Lethal Cryptococcus neoformans Infection | 10.1128/CVI.00202-07 | 2007 |
| Glucuronoxylomannan-mediated interaction of Cryptococcus neoformans with human alveolar cells results in fungal internalization and host cell damage | 10.1016/j.micinf.2005.07.027 | 2006 |
| Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport | 10.1128/EC.00318-06 | 2006 |
| Membrane redistribution of gangliosides and glycosylphosphatidylinositol-anchored proteins in brain tissue sections under conditions of lipid raft isolation | 10.1016/j.bbalip.2004.10.002 | 2005 |
| The multitude of targets for the immune system and drug therapy in the fungal cell wall | 10.1016/j.micinf.2005.03.002 | 2005 |
| Exposure of Human Leukemic Cells to Direct Electric Current: Generation of Toxic Compounds Inducing Cell Death by Different Mechanisms | 10.1385/CBB:42:1:061 | 2005 |
| Structure, Cellular Distribution, Antigenicity, and Biological Functions of Fonsecaea pedrosoi Ceramide Monohexosides | 10.1128/IAI.73.12.7860-7868.2005 | 2005 |
| A monoclonal antibody to glucosylceramide inhibits the growth of Fonsecaea pedrosoi and enhances the antifungal action of mouse macrophages | 10.1016/j.micinf.2004.03.004 | 2004 |
| Intact cell adhesion to glycan microarrays | 10.1093/glycob/cwh022 | 2003 |
| Anti-Ganglioside Antibodies Bind with Enhanced Affinity to Gangliosides Containing Very Long Chain Fatty Acids | 2002 |
Eventos:
(0.00% eventos com DOI)