Paula Alvarez Abreu
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Núcleo em Ecologia e Desenvolvimento Sócio Ambiental de Macaé
Departamento:
Núcleo de Pesquisas Ecológicas de Macaé/NUPEM/Docentes
e-mail:
abreu_pa@yahoo.com.br
Linkedin:
Google Scholar:
ORCID:
https://orcid.org/0000-0003-2204-3012
Formação:
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Universidade Federal Fluminense
Neurociências | Doutorado | 2008 - 2011
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Universidade Federal Fluminense
Neuroimunologia | Mestrado | 2007 - 2008
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Universidade Federal Fluminense
Habilitação em Análises Clínicas | Aperfeiçoamento | 2006 - 2007
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Universidade Federal Fluminense
Farmácia Industrial | Graduação | 2001 - 2006
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:
(79.71% artigos com DOI)
Titulo | DOI | Ano |
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Chemoselective Synthesis of Mannich Adducts from 1,4-Naphthoquinones and Profile as Autophagic Inducers in Oral Squamous Cell Carcinoma | 10.3390/molecules28010309 | 2023 |
Chloroquinolone Carboxamide Derivatives as New Anti-HSV-1 PromisingDrugs | 10.2174/1568026623666221220121806 | 2023 |
Anticancer Activity and Molecular Targets of Piper cernuum Substances in Oral Squamous Cell Carcinoma Models | 10.3390/biomedicines11071914 | 2023 |
Exploring Brazilian Natural Products as Potential Bioactive Compounds against Trypanosoma cruzi by targeting Squalene Synthase | 10.2174/1570180820666230816141241 | 2023 |
Antiviral evaluation of 1,4-disubstituted-1,2,3-triazole derivatives against Chikungunya virus | 10.2217/fvl-2023-0142 | 2023 |
Diacetate Naphthoquinone Derivatives Tethered to 1,2,3-Triazoles: Synthesis and Cytotoxicity Evaluation in Caco-2 Cells | 10.21577/0103-5053.20210123 | 2022 |
Synthesis and Anti-Chikungunya Virus (CHIKV) Activity of Novel 1,4-Naphthoquinone Sulfonamide and Sulfonate Ester Derivatives | 10.21577/0103-5053.20220010 | 2022 |
Pro-Apoptotic Antitumoral Effect of Novel Acridine-Core Naphthoquinone Compounds against Oral Squamous Cell Carcinoma | 10.3390/molecules27165148 | 2022 |
Structural insights into the inhibition of the nsP2 protease from Chikungunya virus by molecular modeling approaches | 10.1007/s00894-022-05316-3 | 2022 |
DIVULGAÇÃO CIENTÍFICA EM VÍDEOS DE EXPERIMENTOS DE QUÍMICA NO YOUTUBE | 2022 | |
Divulgação do uso de polimetilmetacrilato (PMMA) no Youtube: educação em saúde ou incentivo a busca pelo corpo perfeito? | 2022 | |
Desenvolvimento de materiais didáticos voltados à educação em saúde para sensibilização de futuros profissionais de saúde sobre a inclusão de surdos | 2021 | |
ANÁLISE DAS INFORMAÇÕES SOBRE O MEDICAMENTO METILFENIDATO (RITALINA®) DIVULGADAS EM VÍDEOS DO YOUTUBE | 2021 | |
Antiviral activity of 1,4-disubstituted-1,2,3-triazoles against HSV-1 in vitro | 10.3851/IMP3387 | 2021 |
Chás e emagrecimento: uma análise crítica do que está sendo recomendado nos vídeos do youtube | 2021 | |
Acessibilidade da comunidade surda a informações on-line sobre doenças epidêmicas e prevalentes no Brasil para promoção de saúde. | 2021 | |
Ferramentas digitas gratuitas online: um olhar sobre as suas funcionalidades no ensino. | 10.34117/bjdv7n10-121 | 2021 |
Effects of tauroursodeoxycholic acid on glucose homeostasis: Potential binding of this bile acid with the insulin receptor | 10.1016/j.lfs.2021.120020 | 2021 |
DIVULGAÇÃO DE INFORMAÇÃO SOBRE TRATAMENTO DA DEPRESSÃO NO YOUTUBE | 2021 | |
Synthesis of 5-amino-1-aryl-3-methyl-1H-pyrazole-4-carbonitriles, Antifungal Activity and in silico Analysis | 10.2174/1570178617666200210105246 | 2020 |
Targeting Chikungunya virus by computational approaches: from viral biology to the development of therapeutic strategies | 10.1080/14728222.2020.1712362 | 2020 |
O movimento antivacina no YouTube nos tempos de pós-verdade: Educação em saúde ou desinformação? | 10.22409/rmc.v14i1.38210 | 2020 |
Molecular Mechanism of Action of New 1,4-Naphthoquinones tethered to 1,2,3-1H-Triazoles with Cytotoxic and Selective Effect Against Oral Squamous Cell Carcinoma | 10.1016/j.bioorg.2020.103984 | 2020 |
Estratégia de ensino baseada no uso de tecnologias para sensibilização sobre a inclusão de surdos | 2020 | |
O olhar da revista ciência hoje das crianças para o Museu Nacional | 2020 | |
Virtual screening and drug repositioning as strategies for the discovery of new antifungal inhibitors of oxidosqualene cyclase | 10.1016/j.jsbmb.2018.09.001 | 2019 |
Computational strategy for visualizing structures and teaching biochemistry | 10.1002/bmb.21199 | 2019 |
Physical Education: Adaptations and Benefits for Deaf Students | 10.4236/ce.2019.104053 | 2019 |
Understanding the Morphogenesis and Pathogenicity of Candida Albicans: A Way to Interfere and Develop New Antifungals | 10.19080/AIBM.2019.14.555885 | 2019 |
Mechanism of resistance to acyclovir in thymidine kinase mutants from Herpes simplex virus type 1: a computational approach | 10.1080/07391102.2019.1625443 | 2019 |
Etiologia e epidemiologia da tinea capitis: relato de série de casos e revisão da literatura | 10.21877/2448-3877.201800781 | 2019 |
Virtual screening identified compounds that bind to cyclin dependent kinase 2 and prevent herpes simplex virus type 1 replication and reactivation in neurons | 10.1016/j.antiviral.2019.104621 | 2019 |
Class A β-lactamases and inhibitors: In silico analysis of the binding mode and the relationship with resistance | 10.1016/j.jbiotec.2018.05.005 | 2018 |
Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1 H -1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells | 10.1016/j.ejmech.2018.07.018 | 2018 |
Molecular modeling of benzimidazole derivatives: a promising series of GluN2B selective NMDA receptor antagonists | 10.2174/1574885512666171128145952 | 2018 |
A DIVULGAÇÃO DE VÍDEOS DE ANATOMIA DO SISTEMA NERVOSO CENTRAL NO YOUTUBE | 10.17765/1983-1870.2018v11n3p459-465 | 2018 |
Exploring 1,2,3-triazole derivatives by using in vitro and in silico assays to target new antifungal agents and treat Candidiasis | 10.1007/s00044-017-1789-x | 2017 |
Targeting CYP51 for drug design by the contributions of molecular modeling | 10.1111/fcp.12230 | 2017 |
Marine Diterpenes: Molecular Modeling of Thrombin Inhibitors with Potential Biotechnological Application as an Antithrombotic | 10.3390/md15030079 | 2017 |
Design strategies of oxidosqualene cyclase inhibitors: Targeting the sterol biosynthetic pathway | 10.1016/j.jsbmb.2017.05.002 | 2017 |
Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives | 10.1248/cpb.c17-00293 | 2017 |
Atenção Farmacêutica em Pacientes Oncológicos: Uma revisão da literatura | 2016 | |
Structure-activity relationship of a series of 1,2-dihydroquinoline analogues and binding mode with Vibrio cholerae dihydrofolate reductase | 10.1007/s00044-016-1583-1 | 2016 |
Anti-Inflammatory Properties of Pterocarpanquinone LQB-118 in Mice | 10.1016/j.bmc.2016.07.046 | 2016 |
Mycoses and Antifungals: reviewing the basis of a current problem that still is a biotechnological target for marine products | 10.3389/fmars.2014.00012 | 2014 |
Molecular modeling of a series of pyridinecarboxamidrazone-azole derivatives with antifungal activity | 10.1007/s00044-014-1067-0 | 2014 |
Molecular Modeling of a Phenyl-Amidine Class of NMDA Receptor Antagonists and the Rational Design of New Triazolyl-Amidine Derivatives | 10.1111/cbdd.12056 | 2013 |
Tuberculosis, an Old Disease Lacking New Therapeutic Drugs | 10.2174/1574885511308020003 | 2013 |
Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel | 10.3109/14756366.2013.817403 | 2013 |
Tuberculosis: finding a new potential antimycobacterium derivative in a aldehyde-arylhydrazone-oxoquinoline series | 10.1007/s00284-012-0176-6 | 2012 |
Synthesis and antileishmanial activity of new 1-aryl-1H-pyrazole-4-carboximidamides derivatives | 10.1590/S0103-50532011000200022 | 2011 |
Identification of Nor-ß-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain | 10.1007/s00284-010-9763-6 | 2011 |
Looking at the proteases from a simple perspective | 10.1002/jmr.1091 | 2011 |
In Silico Structural Characteristics and α-Amylase Inhibitory Properties of Ric c 1 and Ric c 3, Allergenic 2S Albumins from Ricinus communis Seeds | 10.1021/jf104638b | 2011 |
Oxoquinoline Derivatives: Identification and Structure¿Activity Relationship (SAR) Analysis of New Anti-HSV-1 Agents | 10.1007/s00284-010-9860-6 | 2011 |
Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases | 10.5551/jat.3293 | 2010 |
Synthesis, biological, and theoretical evaluations of new 1,2,3-triazoles against the hemolytic profile of the Lachesis muta snake venom | 10.1016/j.bmc.2009.09.031 | 2009 |
Synthesis, antiviral activity and molecular modeling of oxoquinoline derivatives | 10.1016/j.bmc.2009.06.037 | 2009 |
Sistema de distribuição individualizado: a importância da identificação dos pontos críticos nos processos de dispensação e devolução de materiais e medicamentos | 2009 | |
Synthesis, HIV-RT inhibitory activity and SAR of 1-benzyl-1H-1,2,3-triazole derivatives of carbohydrates | 10.1016/j.ejmech.2008.02.047 | 2008 |
Synthesis of new 4-(phenylamino)thieno[2,3-b]pyridine derivatives and new tetracyclic heteroaromatic system benzo[b]thieno[3,2-h]-1,6-naphthyridines | 2008 | |
DNA-methylation: a promising target for the twenty-first century | 10.1517/14728222.12.8.1035 | 2008 |
Antibacterial profile against drug-resistant Staphylococcus epidermidis clinical strain and structure-activity relationship studies of 1H-Pyrazolo[3,4-b]pyridine and Thieno[2,3-b]pyridine derivatives | 10.1016/j.bmc.2008.07.035 | 2008 |
Identification of a Potential Lead Structure for Designing New Antimicrobials to Treat Infections Caused by Staphylococcus epidermidis-Resistant Strains | 10.1007/s00284-008-9234-5 | 2008 |
Identification and characterization of a new member of snake venom thrombin inhibitors from Bothrops insularis using a proteomic approach. | 10.1016/j.toxicon.2007.11.026 | 2007 |
Metilação do DNA e DNA-metiltransferases: um caminho para a terapia | 2007 | |
Structure-Function Inferences Based On Molecular Modeling, Sequence-Based Methods and Biological Data Analysis of Snake Venom Lectins | 10.1016/j.toxicon.2006.08.006 | 2006 |
Retina de Aves: um modelo para estudos do desenvolvimento do sistema colinérgico central. | 2006 | |
Snake venom: any clue for antibiotics and cam. | 10.1093/ecam/neh063 | 2005 |
Eventos:
(0.00% eventos com DOI)