Marcela de Freitas Lopes
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Programa de Imunobiologia/Biof
Formação:
-
National Institutes of Health
| Pós-Doutorado | 1999 - 2000
-
Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Doutorado | 1991 - 1995
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Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Mestrado | 1988 - 1991
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Universidade Federal de Juiz de Fora
Farmacia e Bioquimica | Graduação | 1984 - 1988
Laboratórios:
Nuvens de Palavras:
Artigos:
(91.07% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Differential regulation of lung homeostasis and silicosis by the TAM receptors MerTk and Axl | 10.3389/fimmu.2024.1380628 | 2024 |
| Immunopathogenesis in Trypanosoma cruzi Infection: A Role for Suppressed Macrophages and Apoptotic Cells | 10.3389/fimmu.2023.1244071 | 2023 |
| Distinct T helper cell-mediated antitumor immunity: T helper 2 cells in focus | 10.1016/j.cpt.2022.11.001 | 2022 |
| Axl receptor induces efferocytosis, dampens M1 macrophage responses and promotes heart pathology in Trypanosoma cruzi infection | 10.1038/s42003-022-04401-w | 2022 |
| From denial to hope: Brazil deals with a prolonged COVID-19 epidemic course | 10.1038/s41590-021-00875-8 | 2021 |
| New therapeutic tools to shape monocyte functional phenotypes in leishmaniasis | 10.3389/fimmu.2021.704429 | 2021 |
| RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages | 10.3389/fimmu.2020.00886 | 2020 |
| Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi | 10.3389/fimmu.2018.00671 | 2018 |
| Trypanosoma cruzi Infection Induces Cellular Stress Response and Senescence-Like Phenotype in Murine Fibroblasts | 10.3389/fimmu.2018.01569 | 2018 |
| LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8+ T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection | 10.3389/fimmu.2017.01291 | 2017 |
| All-Trans Retinoic Acid Promotes an M1- to M2-Phenotype Shift and Inhibits Macrophage-Mediated Immunity to Leishmania major | 10.3389/fimmu.2017.01560 | 2017 |
| Apoptotic CD8 T-lymphocytes disable macrophage-mediated immunity to Trypanosoma cruzi infection | 10.1038/cddis.2016.135 | 2016 |
| Epigenetic Control of Macrophage Shape Transition towards an Atypical Elongated Phenotype by Histone Deacetylase Activity | 10.1371/journal.pone.0132984 | 2015 |
| Infection with Leishmania major Induces a Cellular Stress Response in Macrophages | 10.1371/journal.pone.0085715 | 2014 |
| Innate Immunity to Leishmania Infection: Within Phagocytes | 10.1155/2014/754965 | 2014 |
| Inhibition of caspase-8 activity promotes protective Th1- and Th2-mediated immunity to Leishmania major infection | 10.1189/jlb.0912463 | 2013 |
| Pathogen-Induced Proapoptotic Phenotype and High CD95 (Fas) Expression Accompany a Suboptimal CD8+ T-Cell Response: Reversal by Adenoviral Vaccine | 10.1371/journal.ppat.1002699 | 2012 |
| Immunity to Protozoan Parasites | 10.1155/2012/250793 | 2012 |
| Myeloid-derived suppressor cells help protective immunity to Leishmania major infection despite suppressed T cell responses | 10.1189/jlb.1110608 | 2011 |
| Apoptotic lymphocytes treated with IgG from Trypanosoma cruzi infection increase TNF-α secretion and reduce parasite replication in macrophages | 10.1002/eji.200939606 | 2010 |
| Targeting caspases in intracellular protozoan infections | 10.1080/08923970802332164 | 2009 |
| The importance of apoptosis for immune regulation in Chagas disease | 10.1590/S0074-02762009000900033 | 2009 |
| Inhibition of caspase-8 activity reduces IFN-gamma expression by T cells from Leishmania major infection | 10.1590/S0001-37652008000100008 | 2008 |
| Apoptosis differentially regulates mesenteric and subcutaneous lymph node immune responses toTrypanosoma cruzi | 10.1002/eji.200737582 | 2008 |
| Caspase inhibition reduces lymphocyte apoptosis and improves host immune responses toTrypanosoma cruzi infection | 10.1002/eji.200636790 | 2007 |
| The Fas death pathway controls coordinated expansions of type 1 CD8 and type 2 CD4 T cells in Trypanosoma cruzi infection | 10.1189/jlb.1006643 | 2007 |
| Cross-talk between apoptosis and cytokines in the regulation of parasitic infection | 10.1016/j.cytogfr.2007.01.009 | 2007 |
| Decoding caspase signaling in host immunity to the protozoan Trypanosoma cruzi | 10.1016/j.it.2007.06.004 | 2007 |
| Neutrophils Activate Macrophages for Intracellular Killing of Leishmania major through Recruitment of TLR4 by Neutrophil Elastase | 10.4049/jimmunol.179.6.3988 | 2007 |
| The importance of aberrant T-cell responses in Chagas disease | 10.1016/j.pt.2005.03.008 | 2005 |
| Caspase-8 Activity Prevents Type 2 Cytokine Responses and Is Required for Protective T Cell-Mediated Immunity against Trypanosoma cruzi Infection | 10.4049/jimmunol.174.10.6314 | 2005 |
| Ectopic T cell receptor expression causes B cell immunodeficiency in transgenic mice | 10.1002/eji.200324675 | 2004 |
| Macrophage Interactions with Neutrophils Regulate Leishmania major Infection | 10.4049/jimmunol.172.7.4454 | 2004 |
| Viral FLIP Impairs Survival of Activated T Cells and Generation of CD8+ T Cell Memory | 10.4049/jimmunol.172.10.6313 | 2004 |
| Production and Characterization of a T Cell Receptor Transgenic Mouse Recognizing the Immunodominant Epitope of the Torpedo californica Acetylcholine Receptor | 10.1196/annals.1254.045 | 2003 |
| Apoptosis Underlies Immunopathogenic Mechanisms in Acute Silicosis | 10.1165/ajrcmb.27.1.4717 | 2002 |
| T cell receptor transgenic mice recognizing the immunodominat epitope of Torpedo californica acetylcholine receptor (autoria compartilhada) | 10.1002/1521-4141(200207)32:7<2055::AID-IMMU2055>3.0.CO;2-Q | 2002 |
| Costimulation of Host T Lymphocytes by a Trypanosomal trans-Sialidase: Involvement of CD43 Signaling | 10.4049/jimmunol.168.10.5192 | 2002 |
| Intracellular protozoan parasites and apoptosis: diverse strategies to modulate parasite-host interactions | 10.1016/S1471-4922(01)02016-5 | 2001 |
| FAS Ligand Triggers Pulmonary Silicosis | 10.1084/jem.194.2.155 | 2001 |
| Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages. | 10.1038/35003208 | 2000 |
| Experimental Chagas disease: Phagocytosis of apoptotic lymphocytes deactivates macrophages and fuels parasite growth. | 10.1023/A:1009648311490 | 2000 |
| Apoptotic cells knock down macrophage function and help parasite growth | 2000 | |
| The macrophage haunted by cell ghosts: a pathogen grows. | 10.1016/S0167-5699(00)01713-8 | 2000 |
| Increased Susceptibility Of Fas Ligand-Deficient Gld Mice To Trypanosoma Cruzi Infection Due To A Th2-Biased Host Immune Response | 10.1002/(SICI)1521-4141(199901)29:01<81::AID-IMMU81>3.0.CO;2-Y | 1999 |
| Activation-Induced T Cell Death Exacerbates Replication in Macrophages Cocultured with CD4+ T Lymphocytes from Infected Hosts | 10.4049/jimmunol.160.3.1313 | 1998 |
| Trypanosoma cruzi-induced immunosuppression: selective triggering of CD4+ T-cell death by the T-cell receptor-CD3 pathway and not by the CD69 or Ly-6 activation pathway | 10.1128/iai.64.5.1559-1564.1996 | 1996 |
| Experimental Chagas'Disease: Both Chemically Induced And Triatomine Derived Metacyclic Forms Of Trypanosoma Cruzi Cause Similar Immunological Alterations In The Infected Host | 10.1006/expr.1995.1024 | 1995 |
| Apoptosis As A Cause Of T Cell Unresponsiveness In Experimental Chagas'Disease | 1995 | |
| Partial characterization of the cohemolytic factor produced by Streptococcus uberis and comparison with the CAMP-factor | 10.1111/j.1574-695X.1995.tb00193.x | 1995 |
| Programmed T-cell death in experimental chagas disease | 10.1016/0169-4758(95)80011-5 | 1995 |
| Activation-induced CD4+ T cell death by apoptosis in experimental Chagas' disease. | 10.4049/jimmunol.154.2.744 | 1995 |
| Control Of Differential Cd4+ T Lymphocyte Behavior In Vitro Is Dictated By The Pattern Of Cd Molecule Involvement | 1994 | |
| Trypanosoma cruzi-induced immunosuppression: blockade of costimulatory T-cell responses in infected hosts due to defective T-cell receptor-CD3 functioning | 10.1128/iai.62.4.1484-1488.1994 | 1994 |
| Evaluation Of Cohemolytic Activity In Streptococci, Listeria And Corynebacteria By Using Sheep Blood Agar Plates And A Quantitative Microassay | 1992 | |
| Quantitative Analysis Of Camp Factor Activity In Group B Streptococci By Using An Accurate Microtechnique | 1992 |
Eventos:
(0.00% eventos com DOI)