Elaine Sobral da Costa

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Medicina

Departamento:

Departamento de Pediatria/FM

ORCID:

não disponível no Lattes


Formação:
  • Universidade Federal do Rio de Janeiro

    Clínica Médica | Doutorado | 2004 - 2006
  • Universidade Federal do Rio de Janeiro

    Clínica Médica | Mestrado | 2002 - 2003
  • Universidad de Salamanca

    Citometria de Fluxo | Aperfeiçoamento | 2002 - 2002
  • Universidade Federal do Rio de Janeiro

    Hematologia Pediátrica | Especialização | 1999 - 2001
  • Universidade Federal do Rio de Janeiro

    | Especialização - Residência medica | 1997 - 2000
  • Universidade Federal do Rio de Janeiro

    Medicina | Graduação | 1991 - 1996
Laboratórios:
Nuvens de Palavras:
Artigos:

(97.14% artigos com DOI)

Titulo DOI Ano
- co-occurring with - and RAM immunophenotype in a non-Down syndrome infant with acute megakaryoblastic leukemia 10.1080/10428194.2023.2243532 2023
Editorial: Minimal residual disease (MRD) assessment in multiple myeloma patients 10.3389/fonc.2023.1211935 2023
Phenotypic profiling of CD34+ cells by advanced flow cytometry improves diagnosis of Juvenile Myelomonocytic Leukemia 10.3324/haematol.2023.282805 2023
IKZF1 deletions associate with CRLF2 overexpression leading to a poor prognosis in B-cell precursor acute lymphoblastic leukaemia 10.1016/j.tranon.2021.101291 2022
Immunophenotypic Analysis of Acute Megakaryoblastic Leukemia: A EuroFlow Study 10.3390/cancers14061583 2022
Multicentric standardization of minimal/measurable residual disease in B-cell precursor acute lymphoblastic leukaemia using next-generation flow cytometry in a low/middle-level income country 10.1111/bjh.18499 2022
Bone Marrow Stromal Cell Regeneration Profile in Treated B-Cell Precursor Acute Lymphoblastic Leukemia Patients: Association with MRD Status and Patient Outcome 10.3390/cancers14133088 2022
Global methylation status of LINE-1 in pediatric myelodysplastic syndrome: a predictive biomarker of prognosis? 10.1080/10428194.2022.2115842 2022
Updating recommendations of the Brazilian Group of Flow Cytometry (GBCFLUX) for diagnosis of acute leukemias using four-color flow cytometry panels. 10.1016/j.htct.2021.04.001 2021
Flow Cytometry Immunophenotyping for Diagnostic Orientation and Classification of Pediatric Cancer Based on the EuroFlow Solid Tumor Orientation Tube (STOT) 10.3390/cancers13194945 2021
B-Cell Regeneration Profile and Minimal Residual Disease Status in Bone Marrow of Treated Multiple Myeloma Patients 10.3390/cancers13071704 2021
Chronic Granulomatous Disease and Myelodysplastic Syndrome in a Patient with a Novel Mutation in CYBB 10.3390/genes12101476 2021
KMT2A-MLLT1 and the Novel SEC16A-KMT2A in a Cryptic 3-Way Translocation t(9;11;19) Present in an Infant With Acute Lymphoblastic Leukemia 10.1097/MPH.0000000000002386 2021
Minimal residual disease assessment in acute lymphoblastic leukemia by 4-color flow cytometry: Recommendations from the MRD Working Group of the Brazilian Society of Bone Marrow Transplantation 10.1016/j.htct.2020.09.148 2021
Immunophenotypic shifts during minimal residual evaluation in a case of leukemic form of anaplastic large cell lymphoma ALK + 10.1002/cnr2.1526 2021
Flow cytometric minimal residual disease assessment in B-cell precursor acute lymphoblastic leukaemia patients treated with CD19-targeted therapies - a EuroFlow study 10.1111/bjh.17992 2021

Expression Profiles of DNA Methylation and Demethylation Machinery Components in Pediatric Myelodysplastic Syndrome: Clinical Implications

10.2147/cmar.s219026 2020
Automated identification of leukocyte subsets improves standardization of database-guided expert-supervised diagnostic orientation in acute leukemia: a EuroFlow study 10.1038/s41379-020-00677-7 2020
Risk factors for the development of hospital-acquired pediatric venous thromboembolism-Dealing with potentially causal and confounding risk factors using a directed acyclic graph (DAG) analysis 10.1371/journal.pone.0242311 2020
A New Complex Karyotype Involving a KMT2A-r Variant Three-Way Translocation in a Rare Clinical Presentation of a Pediatric Patient with Acute Myeloid Leukemia 10.1159/000499640 2019
Maturation-associated gene expression profiles during normal human bone marrow erythropoiesis 10.1038/s41420-019-0151-0 2019
From big flow cytometry datasets to smart diagnostic strategies: The EuroFlow approach 10.1016/j.jim.2019.07.003 2019
Blood monitoring of circulating tumor plasma cells by next generation flow in multiple myeloma after therapy 10.1182/blood.2019002610 2019
The Manufacture of GMP-Grade Bone Marrow Stromal Cells with Validated In Vivo Bone-Forming Potential in an Orthopedic Clinical Center in Brazil 10.1155/2019/2608482 2019
Aberrant Expression of EZH2 in Pediatric Patients with Myelodysplastic Syndrome: A Potential Biomarker of Leukemic Evolution 10.1155/2019/3176565 2019
Molecular approaches identify a cryptic MECOM rearrangement in a child with a rapidly progressive myeloid neoplasm 10.1016/j.cancergen.2017.12.002 2018
Differential expression of CD73, CD86 and CD304 in normal vs. leukemic B-cell precursors and their utility as stable minimal residual disease markers in childhood B-cell precursor acute lymphoblastic leukemia 10.1016/j.jim.2018.03.005 2018
International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia 10.1182/blood-2017-12-821363 2018
Maturation-associated gene expression profiles along normal human bone marrow monopoiesis 10.1111/bjh.14467 2017
A unique set of complex chromosomal abnormalities in an infant with myeloid leukemia associated with Down syndrome 10.1186/s13039-017-0335-3 2017
Protector effect of α-thalassaemia on cholecystitis and cholecystectomy in sickle cell disease 10.1080/10245332.2017.1289325 2017
Automated database-guided expert-supervised orientation for immunophenotypic diagnosis and classification of acute leukemia 10.1038/leu.2017.313 2017
Standardized flow cytometry for highly sensitive MRD measurements in B-cell acute lymphoblastic leukemia 10.1182/blood-2016-07-726307 2017
Recombinant L-Asparaginase from Zymomonas mobilis: A Potential New Antileukemic Agent Produced in Escherichia coli 10.1371/journal.pone.0163203 2016
Altered neutrophil immunophenotypes in childhood B-cell precursor acute lymphoblastic leukemia 10.18632/oncotarget.8369 2016
Flow Cytometry as a Diagnostic Support Tool in Juvenile Myelomonocytic Leukemia 10.3109/10428194.2015.1049164 2015
Molecular cytogenetic studies characterizing a novel complex karyotype with an uncommon 5q22 deletion in childhood acute myeloid leukemia 10.1186/s13039-015-0167-y 2015
-First proposed panels on acute leukemia for four-color immunophenotyping by flow cytometry from the Brazilian Group of Flow Cytometry - GBCFLUX- 10.1002/cytob.21175 2014
Cytogenetic as an Important Tool for Diagnosis and Prognosis for Patients with Hypocellular Primary Myelodysplastic Syndrome 10.1155/2014/542395 2014
Contribution of Multiparameter Flow Cytometry Immunophenotyping to the Diagnostic Screening and Classification of Pediatric Cancer 10.1371/journal.pone.0055534 2013
Overview of clinical flow cytometry data analysis: recent advances and future challenges 10.1016/j.tibtech.2013.04.008 2013
Cycle arrest and aneuploidy induced by zidovudine in murine embryonic stem cells 10.1093/mutage/ger093 2012
Section 1: Acute Leukemia Orientation Tube (ALOT) In: EuroFlow antibody panels for standardized n-dimensional flow cytometric immunophenotyping of normal, reactive and malignant leukocytes. On line publication May 21012 2012
Section 5. EuroFlow strategies and tools for data analysis. In: EuroFlow standardization of flow cytometer instrument settings and immunophenotyping protocols. 2012
Analysis of the immune system of multiple myeloma patients achieving long-term disease control by multidimensional flow cytometry 10.3324/haematol.2012.067272 2012
Secondary abnormalities involving 1q or 13q and poor outcome in high stage Burkitt leukemia/lymphoma cases with 8q24 rearrangement at diagnosis 10.1007/s12185-010-0757-8 2011
Radioactive synovectomy with Yttrium90 citrate in haemophilic synovitis: Brazilian experience 10.1111/j.1365-2516.2010.02379.x 2011
Retinoic acid-treated pluripotent stem cells undergoing neurogenesis present increased aneuploidy and micronuclei formation 10.1371/journal.pone.0020667 2011
Birth weight patterns by gestational age in Brazil 10.1590/S0001-37652011005000008 2011
Heme-Oxygenases during Erythropoiesis in K562 and Human Bone Marrow Cells 10.1371/journal.pone.0021358 2011
Overweight as a Prognostic Factor in Children With Acute Lymphoblastic Leukemia 10.1038/oby.2011.195 2011
A rare case of myelodysplastic syndrome with i(9q) in a child associated to osteochondromatosis 10.1002/pbc.23272 2011
The Wnt signaling pathway regulates Nalm-16 b-cell precursor acute lymphoblastic leukemic cell line survival and etoposide resistance? 10.1016/j.biopha.2009.09.005 2010
Harmonization of light scatter and fluorescence flow cytometry profiles obtained after staining peripheral blood leucocytes for cell surface-only versus intracellular antigens with the Fix & Perm reagent 10.1002/cyto.b.20486 2010
Epigenetic alterations of and genes in pediatric primary myelodysplastic syndrome 10.3109/10428194.2010.505820 2010
Automated pattern-guided principal component analysis vs expert-based immunophenotypic classification of B-cell chronic lymphoproliferative disorders: a step forward in the standardization of clinical immunophenotyping 10.1038/leu.2010.160 2010
Positive response to imatinib mesylate therapy for childhood chronic myeloid leukemia 10.1590/S0100-879X2010007500026 2010
Transient myelodysplasia in an infant with Down syndrome preceding acute megakaryoblastic leukemia: cytogenetic and immunophenotypic findings 10.1016/j.cancergencyto.2008.09.003 2009
New Decision Support Tool for Treatment Intensity Choice in Childhood Acute Lymphoblastic Leukemia 10.1109/TITB.2008.925965 2009
Racemic Etodolac is cytotoxic and cytostatic for B-cell precursor acute lymphoblastic leukemia cells? 10.1016/j.biopha.2008.09.009 2009
Sepsis-Related Mortality of Very Low Birth Weight Brazilian Infants: The Role of Pseudomonas aeruginosa 10.1155/2009/427682 2009
Detection of mutations in GATA1 gene using automated denaturing high-performance liquid chromatography and direct sequencing in children with Down syndrome 10.1080/10428190902829433 2009
An uncommon case of childhood biphenotypic precursor-B/T acute lymphoblastic leukemia 10.1002/pbc.21290 2008
Banding and molecular cytogenetic studies detected a CBFB-MYH11 fusion gene that appeared as abnormal chromosomes 1 and 16 in a baby with acute myeloid leukemia FAB M4-Eo. 10.1016/j.cancergencyto.2007.12.014 2008
Generation of flow cytometry data files with a potentially infinite number of dimensions 10.1002/cyto.a.20608 2008
A probabilistic approach for the evaluation of minimal residual disease by multiparameter flow cytometry in leukemic B-cell chronic lymphoproliferative disorders 10.1002/cyto.a.20638 2008
A Multidimensional Classification Approach for the Automated Analysis of Flow Cytometry Data 10.1109/tbme.2008.915729 2008
A new automated flow cytometry data analysis approach for the diagnostic screening of neoplastic B-cell disorders in peripheral blood samples with absolute lymphocytosis 10.1038/sj.leu.2404241 2006
Normal hematopoiesis is maintained by activated bone marrow CD4 T cells 10.1182/blood-2004-07-2856 2005
T-lymphocyte function from peripheral blood stem-cell donors is ihibited by activated granulocytes 10.1080/14653240310002252 2003
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Generation of flow cytometry data files with a potentially infiinte number of dimensions 2008
A probabilistic approach for minimal residual disease detection by multiparametric flow cytometry in B-cell chronic lymphoproliferative disorders 2008
A NEW AUTOMATED FLOW CYTOMETRY DATA MERGING AND ESTIMATION APPROACH FOR THE GENERATION OF ?N?-MULTI-DIMENSIONAL SPACES: COMPARISON BETWEEN ORIGINALLY MEASURED AND ESTIMATED IMMUNOPHENOTYPIC DATA ON A SERIES OF B-CELL CHRONIC LYMPHOPROLIFERATIVE DISORDERS (apresentação oral) 2007
Acute Lymphoblastic Leukemia Tratment in Childhood: A new Decision-Support-Tool 2007
A new automated flow cytometry data merging and estimation approach for immunophenotypic data of B-cell chronic lymphoproliferative disease 2007
An automated screening of neoplastic B-cell disorders in peripheral blood samples with absolute lymphocytosis (apresentação oral) 2007
Staining for intracellular BCL2 by flow cytometry: impact of fixation-associated variables on the light scatter and fluorescence characteristics of peripheral blood leukocytes (poster com visita guiada) 2007
Um caso incomum de leucemia linfoblástica aguda bifenotípica de precursor B/T em lactente. 2005
Input and Data Selection Applied to Heart Disease Diagnosis. 2005
Micose Fungóide na Infância: diagnóstico tardio. 2005
Variable selection and neural networks applied to the classification of risk of adverse event in Childhood Leukemia 2003
Classification Of Risk Of Adverse Event In Childhood Leukemia: New Results On Variable Selection 2003
Variable selection and neural networks applied to the classification of risk of adverse event inchildhood leukemia 2003
Correspondence Analyses To Evaluate Geographic Heterogeneity Of LeukemiaSubtypes In Brazil 2003
Implementação da detecção de doença residual minima em leucemia linfoblastica aguda da infancia por citometria de fluxo (apresentação oral) 2003
Evolução clonal na doença residual mínima por citometria de fluxo 2003
CD4+ T cells maintain normal hematopoiesis 2003
CitoKohonen: Aprendizado Estatístico e Redes Neurais em Citometria de Fluxo 2002
Desenvolvimento de um novo método para detecção de doença residual em LLA: aprendizado estatístico e redes neurais em citometria de fluxo (apresentação oral) 2002
Preliminary results in minimal residual disease detection in ALL in childhood? citokohonen: statistic learning and neural network in flow cytometry 2002
Activated Granulocytes From G-CSF treated hemopoietic Stem-Cell Donors, inhibit T cell function 2002
Granulocyte form G-CSF treated hemopoietic stem cell donors inhibit T cell function 2002
Granulocytes from G-CSF treated hemopoietic stem cell donors inhibit G-IFN production by T cells 2002
Granulócitos ativados presentes no sangue periférico de doadores mobilizados com G-CSF inibem a função dos linfócitos T 2002
Normal vc Nude mice: a role for T cells in Granulopoiesis 2002
Fatores Prognósticos na LLA na Infância: analise prospectiva de 55 casos tratados com protocolos baseados no BFM90 e BFM95 (apresentação oral) 1999
Publicações:
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