André Luis Souza dos Santos
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Microbiologia
Departamento:
Departamento de Microbiologia Geral/IM
e-mail:
andre@micro.ufrj.br
Linkedin:
andré-santos-6b502b89
Google Scholar:
B8-h6OUAAAAJ&hl=pt-BR
ORCID:
https://orcid.org/0000-0003-0821-8592
Formação:
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Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Doutorado | 2000 - 2002
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Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Mestrado | 1999 - 2000
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Universidade Federal do Rio de Janeiro
Microbiologia e Imunologia | Graduação | 1994 - 1999
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Escola Técnica Federal de Química do Rio de Janeiro
| Ensino Profissional de nível técnico | 1990 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:
(34.45% artigos com DOI)
Titulo | DOI | Ano |
---|---|---|
Antifungal potential of the new copper(II)-theophylline/1,10-phenanthroline complex against medically relevant drug-resistant Candida species | 2024 | |
Manganese(II), copper(II) and silver(I) complexes containing 1,10-phenanthroline/1,10-phenanthroline-5,6-dione against Candida species | 2024 | |
Extracellular vesicles from Scedosporium apiospermum mycelial cells: implication for fungal-host interplays | 2024 | |
Feline leishmaniasis: evidence-based treatments - challenges to be solved | 2024 | |
Unveiling the antifungal mechanisms of CTP, a new copper(II)-theophylline/1,10-phenanthroline complex, on drug-resistant non-albicans Candida species | 2024 | |
Isopentyl caffeate as a promising drug for the treatment of leishmaniasis: an in silico and in vivo study | 2024 | |
The anti-Leishmania amazonensis and anti-Leishmania chagasi action of copper(II) and silver(I) 1,10‑phenanthroline‑5,6‑dione coordination compounds | 2023 | |
Oxidative damage by 1,10-phenanthroline-5,6-dione and its silver and copper complexes lead to apoptotic-like death in Trichomonas vaginalis | 2023 | |
Active Cu(II), Mn(II) and Ag(I) 1,10-phenanthroline/1,10-phenanthroline-5,6-dione/dicarboxylate chelates on Scedosporium | 2023 | |
Silver(I) 1,10-phenanthroline complexes are active compounds against Fonsecaea pedrosoi and negatively modulate its potential virulence attributes | 2023 | |
Metallopeptidases as key virulence attributes of clinically relevant protozoa: new discoveries, perspectives, and frontiers of knowledge | 2023 | |
SARS-CoV-2 post-infection and sepsis by Saccharomyces cerevisiae: a fatal case report - focus on fungal susceptibility and potential virulence attributes | 2023 | |
Wound dressing using graphene quantum dots: a proof of concept | 2023 | |
Mebendazole inhibits Histoplasma capsulatum growth and decreases mitochondrion and cytoskeleton protein levels | 2023 | |
Combination of farnesol with common antifungal drugs: inhibitory effect against clinical isolates of Candida species | 2023 | |
Scedosporium/Lomentospora species induce the production of siderophores by Pseudomonas aeruginosa in a cystic fibrosis mimic environment | 2023 | |
Cell dispersion during biofilm formation by Scedosporium apiospermum, Scedosporium aurantiacum, Scedosporium minutisporum and Lomentospora prolificans | 2023 | |
Oral candidiasis in patients with kidney transplantation in Iran: prevalence and antifungal susceptibility pattern | 2023 | |
Peptidases are potential targets to copper(II)-1,10-phenanthroline-5,6-dione complex, a new promising and potent drug against Trichomonas vaginalis | 2023 | |
In vitro effects of aminopyridyl ligands complexed to copper(II) on the physiology and interaction process of Trypanosoma cruzi | 2023 | |
Paving the way to an antivirulence strategy against fungal pathogens: lessons learned from Candida albicans | 2023 | |
Bioproducts from Passiflora cincinnata seeds: The Brazilian Caatinga passion fruit | 2023 | |
Silver(I) and copper(II) 1,10-phenanthroline-5,6-dione complexes as promising antivirulence strategy against Leishmania: focus on gp63 (leishmanolysin) | 2023 | |
Fibronectin-binding molecules of Scedosporium apiospermum: focus on adhesive events | 2023 | |
Repurposing benzimidazoles against causative agents of chromoblastomycosis: albendazole has superior in vitro activity than mebendazole and thiabendazole | 2023 | |
Remarkable antibiofilm activity of ciprofloxacin, cefoxitin, and tobramycin, by themselves or in combination, against enteroaggregative Escherichia coli in vitro | 2023 | |
Candida palmioleophila: a new emerging threat in Brazil? | 2023 | |
Cell aggregation capability of clinical isolates from Candida auris and Candida haemulonii species complex | 2023 | |
Chagas disease control - many approaches to prospect | 2023 | |
Development of echinocandin resistance in Candida haemulonii: an emergent, widespread, and opportunistic fungal pathogen | 2023 | |
Antimicrobial and antibiofilm activities of copper(II)-1,10-phenanthroline-5,6-dione against commensal bacteria and fungi responsible for vaginal microbiota dysbiosis | 2023 | |
Tropical infectious diseases of global significance: insights and perspectives | 2023 | |
Therapeutic strategies against Leishmania and Trypanosoma | 2023 | |
Dechlorination of wastewater from shell-based glucosamine processing by mangrove wetland-derived fungi | 2023 | |
Tratamento da leishmaniose canina no Brasil: uma revisão | 2023 | |
Association between culture and the preference for, and perceptions of, 11 routes of medicine administration: a survey in 21 countries and regions | 2023 | |
Prevalence, molecular identification and genotyping of Candida species recovered from oral cavity among patients with diabetes mellitus from Tehran, Iran | 2022 | |
Biofilm formation in clinically relevant filamentous fungi: a therapeutic challenge | 2022 | |
Copper(II) and silver(I)-1,10-phenanthroline-5,6-dione complexes interact with double-stranded DNA: further evidence of their apparent multi-modal activity towards Pseudomonas aeruginosa | 2022 | |
Synthesis and photophysical properties of metal complexes of curcumin dyes: solvatochromism, acidochromism, and photoactivity | 2022 | |
Synthetic derivatives against wild-type and non-wild-type Sporothrix brasiliensis: in vitro and in silico analyses | 2022 | |
The enhanced expression of cruzipain-like molecules in the phytoflagellate Phytomonas serpens recovered from the invertebrate and plant hosts | 2022 | |
Brazilian scientists: much to learn from the microbial biofilm lifestyle (a resistant, resilient, well-orchestrated, and dynamic organization) | 2022 | |
Surface characteristics and microbiological analysis of a vat photopolymerization additive manufacturing dental resin | 2022 | |
A stroll through the history of monoxenous trypanosomatids infection in vertebrate hosts | 2022 | |
Umbu peel as source of antioxidant, antimicrobial and α-amylase inhibitor compounds | 2022 | |
Repositioning drug strategy against Trypanosoma cruzi: lessons learned from HIV aspartyl peptidase inhibitors | 2022 | |
Novel treatment approaches to combat trichomoniasis, a neglected and sexually transmitted infection caused by Trichomonas vaginalis: translational perspectives | 2022 | |
Proteolytic inhibitors as alternative medicines to treat trypanosomatid-caused diseases: experience with calpain inhibitors | 2022 | |
Molecular mechanisms of action of trypanocidal and leishmanicidal drugs with focus on novel chemotherapeutic strategies: creation of a Brazilian multicenter working group | 2022 | |
Antileishmanial efficacy of the calpain inhibitor MDL28170 in combination with amphotericin B | 2022 | |
Ultrastructural and enzymatic alterations in the ovary of Rhodnius prolixus infected with Trypanosoma rangeli | 2022 | |
Prospective medicines against the widespread, emergent and multidrug-resistant opportunistic fungal pathogen Candida auris: a breath of hope | 2022 | |
Decoding the antifungals resistance mechanisms in biofilms of emerging, ubiquitous and multidrug-resistant species belonging to the Scedosporium/Lomentospora genera | 2022 | |
The threat called Candida haemulonii species complex in Rio de Janeiro, Brazil: focus on antifungal resistance and virulence attributes | 2022 | |
Differences in charge distribution in Leishmania tarentolae leishmanolysin result in a reduced enzymatic activity | 2022 | |
Extraction and characterization of β-viginin protein hydrolysates from Cowpea flour as a new manufacturing active ingredient | 2022 | |
Biofilm formation by chromoblastomycosis fungi Fonsecaea pedrosoi and Phialophora verrucosa: involvement with antifungal resistance | 2022 | |
Influence of oral biofilm index, caries experience, and laboratory markers of disease progression on the oral carriage of Candida in HIV-infected and non-infected children: a cross sectional study | 2022 | |
Decoding the anti-Leishmania braziliensis activity of 1,10-phenanthroline-5,6-dione and its silver- and copper-based complexes: in vitro and in vivo assays | 2022 | |
Extracellularly released molecules by the multidrug-resistant fungal pathogens belonging to the Scedosporium genus: an overview focused on their ecological significance and pathogenic relevance | 2022 | |
Halobacillus blutaparonensis strain M9 as a source of extracellular serine peptidases with properties for biotechnological purposes | 2021 | |
Pieces of the complex puzzle of cancer cell energy metabolism: an overview of energy metabolism and alternatives for targeted cancer therapy | 2021 | |
Biological properties of functional flavoring produced by enzymatic esterification of citronellol and geraniol present in Cymbopogon winterianus essential oil | 2021 | |
Azithromycin use in COVID-19 patients: implications on the antimicrobial resistance | 2021 | |
Physical stability enhancement and antimicrobial properties of a sodium ionic cocrystal with theophylline | 2021 | |
Overcoming multi-resistant Leishmania treatment by nanoencapsulation of potent antimicrobials | 2021 | |
Impact of biofilm formation and azoles' susceptibility in Scedosporium/Lomentospora species using an in vitro model that mimics the cystic fibrosis patients' airway environment | 2021 | |
The serine peptidase inhibitor N-ρ-tosyl-L-phenylalanine chloromethyl ketone (TPCK) affects cell biology of Candida haemulonii species complex | 2021 | |
Influence of relevant cystic fibrosis bacteria on Scedosporium apiospermum and Scedosporium boydii growth and viability | 2021 | |
Antimycotic nail polish based on humic acid-coated silver nanoparticles for onychomycosis | 2021 | |
The diverse calpain family in Trypanosomatidae: functional proteins devoid of proteolytic activity? | 2021 | |
Citrus sinensis essential oil-based microemulsions: green synthesis, characterization and antibacterial and larvicide activities | 2021 | |
Antibacterial activity and carbapenem re-sensitizing ability of 1,10-phenanthroline-5,6-dione and its metal complexes against KPC-producing Klebsiella pneumoniae clinical strains | 2021 | |
Silver(I) and copper(II) complexes of 1,10-phenanthroline-5,6-dione against Phialophora verrucosa: a focus on the interaction with human macrophages and Galleria mellonella larvae | 2021 | |
Are Nanobiosensors an Improved Solution for Diagnosis of Leishmania? | 2021 | |
In vitro effects of bis(N-[4-(hydroxyphenyl)methyl]-2-pyridinemethamine)zinc perchlorate monohydrate 4 on the physiology and interaction process of Leishmania amazonensis. | 2021 | |
COVID-19 and diabetes mellitus: potential metabolic associations | 2021 | |
Doxycycline treatment reestablishes renal function of wistar rats in experimental envenomation with Bothrops jararacussu venom | 2021 | |
Repositioning lopinavir, an HIV protease inhibitor, as a promising antifungal drug: lessons learned from Candida albicans - in silico, in vitro and in vivo approaches | 2021 | |
Protease inhibitors as promising weapons against COVID-19: focus on repurposing of drugs used to treat HIV and HCV infections | 2021 | |
Lopinavir and nelfinavir induce the accumulation of crystalloid lipid inclusions within the reservosomes of Trypanosoma cruzi and inhibit both aspartyl-type peptidase and cruzipain activities detected in these crucial organelles | 2021 | |
Analysis of the mechanisms of action of isopentenyl caffeate against Leishmania | 2021 | |
Exploring innovative leishmaniasis treatment: drug targets from pre-clinical to clinical findings | 2021 | |
Anti-Leishmania braziliensis activity of 1,10-phenanthroline-5,6-dione and its Cu(II) and Ag(I) complexes | 2021 | |
Cashew gum (Anacardium occidentale) as a potential source for the production of tocopherol-loaded nanoparticles: formulation, release profile and cytotoxicity | 2021 | |
Bacterial and fungal colonization on metallic and ceramic orthodontic brackets: a scanning electronic microscopy study | 2021 | |
Insights into the interaction of Scedosporium apiospermum, Scedosporium aurantiacum, Scedosporium minutisporum and Lomentospora prolificans with lung epithelial cells | 2020 | |
Saccharide sources do not influence the biofilm formation in Scedosporium/Lomentospora species | 10.1017/exp.2019.5 | 2020 |
Surface, adhesiveness and virulence aspects of Candida haemulonii species complex | 2020 | |
Aspartic peptidase of Phialophora verrucosa as target of HIV peptidase inhibitors: blockage of its enzymatic activity and interfere with fungal growth and macrophage interaction | 2020 | |
Drug repurposing strategy against fungal biofilms | 2020 | |
Histoplasma capsulatum-induced extracellular DNA trap release in human neutrophils | 2020 | |
In vivo activity of copper(II), manganese(II) and silver(I) 1,10-phenanthroline chelates against Candida haemulonii using the Galleria mellonella model | 2020 | |
Environmentally friendly rhamnolipid production for petroleum remediation | 2020 | |
Unmasking the amphotericin B resistance mechanisms in Candida haemulonii species complex | 2020 | |
Trimesic acid-theophylline and isopthalic acid-caffeine cocrystals: synthesis, characterization, solubility, molecular docking and antimicrobial activity | 2020 | |
Secreted aspartyl peptidases by the emerging, opportunistic and multidrug-resistant fungal pathogens comprising the Candida haemulonii complex | 2020 | |
Biofilms formed by Scedosporium and Lomentospora species: focus on the extracellular matrix | 2020 | |
Coinfection of domestic felines by distinct Sporothrix brasiliensis in the Brazilian sporotrichosis hyperendemic area | 2020 | |
Analyzing ambiguities in trypanosomatids taxonomy by barcoding | 2020 | |
Funding for Chagas disease: a 10-year (2009 - 2018) survey | 2020 | |
Naringenin-functionalized multi-walled carbon nanotubes: a potential approach for site-specific remote-controlled anticancer delivery for the treatment of lung cancer | 2020 | |
Biofilm Formed by Candida haemulonii Species Complex: Structural Analysis and Extracellular Matrix Composition | 10.3390/jof6020046 | 2020 |
Antimicrobial action of 1,10-phenanthroline-based compounds on carbapenemase-producing Acinetobacter baumannii clinical strains: efficacy against planktonic- and biofilm-growing cells | 2020 | |
Chemical characterization, antioxidant and antimicrobial activities of açaí seed (Euterpe oleracea Mart.) extracts containing A- and B-type procyanidins | 2020 | |
Pathogenicity Levels of Colombian Strains of Candida auris and Brazilian Strains of Candida haemulonii Species Complex in Both Murine and Galleria mellonella Experimental Models | 10.3390/jof6030104 | 2020 |
Fungal infections in COVID-19 positive individuals: a lack of optimal treatment options | 2020 | |
Candida albicans isolated from denture-related stomatitis in elderly patients: Antifungal susceptibility and production of virulence attributes | 10.1017/exp.2020.49 | 2020 |
B-cyclodextrin/isopentyl caffeate inclusion complex: synthesis, characterization and antileishmanial activity | 2020 | |
Expression and cellular localization of Trypanosoma cruzi calpains | 2020 | |
Susceptibility of the Candida haemulonii Complex to Echinocandins: Focus on Both Planktonic and Biofilm Life Styles and a Literature Review | 10.3390/jof6040201 | 2020 |
Insights into the multi-azole resistance profile in Candida haemulonii species complex | 10.3390/jof6040215 | 2020 |
Contaminação fúngica em sucos de cana-de-açúcar comercializados em Teresina, Piauí, Brasil | 2020 | |
Insights into the social life and obscure side of Scedosporium/Lomentospora species: ubiquitous, emerging and multidrug-resistant opportunistic pathogens | 2019 | |
Anti-Trichomonas vaginalis activity of 1,10-phenanthroline-5,6-dione-based drugs and synergistic effect with metronidazole | 2019 | |
Identification of cell-associated and secreted serine-type peptidases in multidrug-resistant emergent pathogens belonging to the Candida haemulonii complex | 2019 | |
Repositioning of HIV aspartyl peptidase inhibitors for combating the neglected human pathogen Trypanosoma cruzi | 2019 | |
Chymotrypsin- and trypsin-like activities secreted by the fungal pathogens forming the Candida haemulonii complex | 2019 | |
Use of pharmaceutical nanotechnology for the treatment of leishmaniasis | 2019 | |
The serine peptidase inhibitor TPCK induces several morphophysiological changes in the opportunistic fungal pathogen Candida parapsilosis sensu stricto | 2019 | |
New and promising chemotherapeutics for emerging infections involving drug-resistant non-albicans Candida species | 2019 | |
Anti-virulence strategy against the multidrug-resistant bacterial pathogen Pseudomonas aeruginosa: pseudolysin (elastase B) as a potential druggable target | 2019 | |
Leishmaniasis and Chagas disease - neglected tropical diseases: treatment updates | 2019 | |
Participation of Trypanosoma cruzi gp63 molecules on the interaction with Rhodnius prolixus | 2019 | |
Current challenges and updates on therapy of fungal infections | 2019 | |
Miltefosine-lopinavir combination therapy against Leishmania infantum infection: in vitro and in vivo approaches | 2019 | |
Synthesis and antimicrobial activity of a phenanthroline-isoniazid hybrid ligand and its Ag+ and Mn2+ complexes | 2019 | |
In vitro effects of the asymmetric peptidomimetic 157, containing L-tartaric acid core and valine/leucine substituents, on Leishmania amazonensis promastigotes and amastigotes | 2019 | |
Disarming Pseudomonas aeruginosa virulence by the inhibitory action of 1,10-phenanthroline-5,6-dione-based compounds: elastase B (lasB) as a chemotherapeutic target | 2019 | |
Typical and atypical enteroaggregative Escherichia coli clinical strains are both virulent in the Galleria mellonella model | 2019 | |
Calpains of Leishmania braziliensis: genome analysis, differential expression in metacyclogenesis and effects of MDL28170 | 2019 | |
Hydrolytic enzymes (proteases and lipases) released by biofilm-forming cells of Scedosporium/Lomentospora species | 2019 | |
Proteolytic potential of enzymes produced by Candida parapsilosis and Rhodotorula mucilaginosa isolated from liquid whey | 2019 | |
In vitro selection of Phytomonas serpens cells resistant to the calpain inhibitor MDL28170: alterations in fitness and expression of the major peptidases and efflux pumps | 2018 | |
Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury | 2018 | |
Asymmetric peptidomimetics containing L-tartaric acid core inhibit the aspartyl peptidase activity and growth of Leishmania amazonensis promastigotes | 2018 | |
Pseudolysin (elastase B): a protagonist in the Pseudomonas aeruginosa pathogenesis | 2018 | |
Primary evidences of the mechanisms of action of HIV aspartyl peptidase inhibitors on Trypanosoma cruzi trypomastigote forms | 2018 | |
Iranian HIV/AIDS patients with oropharyngeal candidiasis: identification, prevalence and antifungal susceptibility of Candida species | 2018 | |
Scedosporium apiospermum, Scedosporium aurantiacum, Scedosporium minutisporum and Lomentospora prolificans: a comparative study of surface molecules produced by conidial and germinated conidial cells | 2018 | |
Lopinavir, an HIV-1 peptidase inhibitor, induces alteration on the lipid metabolism of Leishmania amazonensis promastigotes | 2018 | |
Susceptibility of promastigotes and intracellular amastigotes from distinct Leishmania species to the calpain inhibitor MDL28170 | 2018 | |
Novel antimony(III) hydroxamic acid complexes as potential anti-leishmanial agents | 2018 | |
Surface properties, adhesion and biofilm formation on different surfaces by Scedosporium spp. and Lomentospora prolificans | 2018 | |
Fonsecaea pedrosoi sclerotic cells: secretion of aspartic-type peptidase and susceptibility to peptidase inhibitors | 2018 | |
Unprecedented in vitro antitubercular activitiy of manganese(II) complexes containing 1,10-phenanthroline and dicarboxylate ligands: increased activity, superior selectivity and lower toxicity in comparison to their copper(II) analogues | 2018 | |
What are the advantages of living in a community? A microbial biofilm perspective! | 2018 | |
Virulence of Candida haemulonii complex in Galleria mellonella and efficacy of classical antifungal drugs: a comparative study with other clinically relevant non-albicans Candida species | 2018 | |
Rutin derivatives obtained by transesterification reactions catalyzed by Novozym 435: antioxidant properties and absence of toxicity in mammalian cells | 2018 | |
Ultrastructural viewpoints on the interaction events of Scedosporium apiospermum conidia with lung and macrophage cells | 2018 | |
Docking simulation between HIV peptidase inhibitors and Trypanosoma cruzi aspartyl peptidase | 2018 | |
Different classes of hydrolytic enzymes produced by multidrug-resistant yeasts comprising the Candida haemulonii complex | 2017 | |
Heterogeneous production of proteases from Brazilian clinical isolates of Pseudomonas aeruginosa | 2017 | |
The widespread anti-protozoal action of HIV aspartic peptidase inhibitors: focus on Plasmodium spp., Leishmania spp. and Trypanosoma cruzi | 2017 | |
Fungal biofilm - a real obstacle against an efficient therapy: lessons from Candida | 2017 | |
Susceptibility of Phytomonas serpens to calpain inhibitors in vitro: interference on the proliferation, ultrastructure, cysteine peptidase expression and interaction with the invertebrate host | 2017 | |
Why calpain inhibitors are interesting leading compounds to search for new therapeutic options to treat leishmaniasis? | 2017 | |
Direct electric current modifies important cellular aspects and ultrastructure features of Candida albicans yeasts: influence of doses and polarities | 2017 | |
Planktonic growth and biofilm formation profiles in Candida haemulonii species complex | 2017 | |
Old drugs × new perspectives/new compounds × old necessities: focusing on combating microbial resistance - Part I | 2017 | |
Old drugs × new perspectives/new compounds × old necessities: focusing on combating microbial resistance - Part II | 2017 | |
1,10-Phenanthroline-5,6-dione-based compounds are effective in disturbing crucial physiological events of Phialophora verrucosa | 2017 | |
Deciphering the effects of nelfinavir and lopinavir on epimastigote forms of Trypanosoma cruzi | 2017 | |
Glycosylated metal chelators as anti-parasitic agents with tunable selectivity | 2017 | |
Relationship between the antifungal susceptibility profile and the production of virulence-related hydrolytic enzymes in Brazilian clinical strains of Candida glabrata | 2017 | |
HIV aspartic peptidase inhibitors modulate surface molecules and enzyme activities involved with physiopathological events in Fonsecaea pedrosoi | 2017 | |
Antifungal potential of copper(II), manganese(II) and silver(I) 1,10-phenanthroline chelates against multidrug-resistant fungal species forming the Candida haemulonii complex: impact on the planktonic and biofilm lifestyles | 2017 | |
The potent cell permeable calpain inhibitor MDL28170 affects the interaction of Leishmania amazonensis with macrophages and shows anti-amastigote activity | 2017 | |
Onychomycosis in workers from a community garden in Teresina, Piauí, Brazil | 2017 | |
Trichosporon asahii secretes a 30-kDa aspartic peptidase | 2017 | |
Uma Corrida Metabólica | 2017 | |
Fungal infections: a veritable worldwide problem | 2017 | |
Anti-Pseudomonas aeruginosa activity of 1,10-phenanthroline-based drugs against both planktonic- and biofilm-growing cells | 2016 | |
First description of Candida nivariensis in Brazil: antifungal susceptibility profile and potential virulence attributes | 2016 | |
Assessment of biofilm formation by Scedosporium apiospermum, S. aurantiacum, S. minutisporum and Lomentospora prolificans | 2016 | |
Candida albicans involvement in denture-related stomatitis: a serious and real clinical concern | 2016 | |
Conidial germination in Scedosporium apiospermum, S. aurantiacum, S. minutisporum and Lamentospora prolificans: influence of growth conditions and antifungal susceptibility profiles | 2016 | |
HIV aspartic peptidase inhibitors are effective drugs against the trypomastigote form of the human pathogen Trypanosoma cruzi | 2016 | |
Nelfinavir and lopinavir impair Trypanosoma cruzi trypomastigotes infection in mammalian host cells and reveal anti-amastigote activity | 2016 | |
Detection of proteases from Sporosarcina aquimarina and Algoriphagus antarcticus isolated from Antarctic soil samples | 2015 | |
Candida haemulonii complex: species identification and antifungal susceptibility profiles of clinical isolates from Brazil | 2015 | |
1,10-Phenanthroline inhibits the metallopeptidase secreted by Phialophora verrucosa and modulates its growth, morphology and differentiation | 2015 | |
Protease and phospholipase activities of Candida spp. isolated from cutaneous candidiasis | 2015 | |
Cruzipain: an update on its potential as chemotherapy target against the human pathogen Trypanosoma cruzi | 2015 | |
New antimicrobial therapeutics | 2015 | |
Candida parapsilosis (sensu lato) isolated from hospitals located in the Southeast of Brazil: species distribution, antifungal susceptibility and virulence attributes | 2015 | |
Expression of calpain-like proteins and effects of calpain inhibitors on the growth rate of Angomonas deanei wild type and aposymbiotic strains | 2015 | |
Perspectives to combat microbial resistance | 2015 | |
Biofilm: a robust and efficient barrier to antifungal chemotherapy | 2015 | |
The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes | 10.1371/journal.pone.0087659 | 2014 |
Enzymes produced by halotolerant spore-forming gram-positive bacterial strains isolated from a resting habitat (Restinga de Jurubatiba) in Rio de Janeiro, Brazil: focus on proteases | 2014 | |
Decoding the Anti-Trypanosoma cruzi Action of HIV Peptidase Inhibitors Using Epimastigotes as a Model | 10.1371/journal.pone.0113957 | 2014 |
Virulence attributes in Brazilian clinical isolates of Pseudomonas aeruginosa | 10.1016/j.ijmm.2014.07.001 | 2014 |
Leishmaniasis: history, evolution of treatment and the need for new drugs | 2014 | |
Aspartic protease inhibitors: effective drugs against the human fungal pathogen Candida albicans | 2013 | |
Nelfinavir is effective in inhibiting the multiplication and aspartic peptidase activity of Leishmania species, including strains obtained from HIV-positive patients | 10.1093/jac/dks410 | 2013 |
Extracellular proteases of Halobacillus blutaparonensis strain M9, a new moderately halophilic bacterium | 2013 | |
Aspartic Peptidases of Human Pathogenic Trypanosomatids: Perspectives and Trends for Chemotherapy | 10.2174/0929867311320250007 | 2013 |
Editorial (Hot Topic: Proteolytic Inhibitors: Implications on Microorganisms Development, Virulence and Pathogenesis) | 10.2174/09298673113209990174 | 2013 |
Calpains: Potential Targets for Alternative Chemotherapeutic Intervention Against Human Pathogenic Trypanosomatids | 10.2174/0929867311320250010 | 2013 |
Phenotypical properties associated with virulence from clinical isolates belonging to the Candida parapsilosis complex | 10.1111/1567-1364.12092 | 2013 |
Effects of direct electric current on Herpetomonas samuelpessoai: an ultrastructural study | 10.1002/bem.20712 | 2012 |
Cellular characterisation of Candida tropicalis presenting fluconazole-related trailing growth | 2012 | |
Deciphering the antimicrobial activity of phenanthroline chelators | 2012 | |
Differential expression of cruzipain- and gp63-like molecules in the phytoflagellate trypanosomatid Phytomonas serpens induced by exogenous proteins | 10.1016/j.exppara.2011.10.005 | 2012 |
Proteomic analysis of the secretions of Pseudallescheria boydii, a human fungal pathogen with unknown genome | 10.1021/pr200875x | 2012 |
Antimicrobial action of chelating agents: repercussions on the microorganism development, virulence and pathogenesis | 2012 | |
Multiple effects of pepstatin A on Trypanosoma cruzi epimastigote forms | 10.1007/s00436-011-2796-3 | 2012 |
Corynebacterium diphtheriae 67-72p hemagglutinin, characterized as the protein DIP0733, contributes to invasion and induction of apoptosis in HEp-2 cells | 10.1016/j.micpath.2011.12.003 | 2012 |
Surface phosphatase in Rhinocladiella aquaspersa: biochemical properties and its involvement with adhesion | 10.3109/13693786.2011.653835 | 2012 |
In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(II) and silver(I) complexes | 10.1039/c2tx00010e | 2012 |
Evidence that a laminin-like insect protein mediates early events in the interaction of a phytoparasite with its vector's salivary gland | 10.1371/journal.pone.0048170 | 2012 |
Cruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus midgut | 10.1371/journal.pntd.0001958 | 2012 |
Metallopeptidase inhibitors arrest vital biological processes in the fungal pathogen Scedosporium apiospermum | 10.1111/j.1439-0507.2009.01767.x | 2011 |
Aspartic proteases of human pathogenic fungi are prospective targets for the generation of novel and effective antifungal inhibitors | 10.2174/157340811796575281 | 2011 |
MDL28170, a calpain inhibitor, affects Trypanosoma cruzi metacyclogenesis, ultrastructure and attachment to Rhodnius prolixus midgut | 10.1371/journal.pone.0018371 | 2011 |
Protease expression by microorganisms and its relevance to crucial physiological/pathological events | 10.4331/wjbc.v2.i3.48 | 2011 |
Aspartic protease inhibitors as potential anti-Candida albicans drugs: impacts on fungal biology, virulence and pathogenesis | 2011 | |
Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes | 10.1590/S0074-02762011000400021 | 2011 |
Multiple effects of amprenavir against Candida albicans | 10.1111/j.1567-1364.2009.00595.x | 2010 |
Leishmanolysin-like molecules in Herpetomonas samuelpessoai mediate hydrolysis of protein substrates and interaction with insect | 10.1016/j.protis.2010.02.001 | 2010 |
A new experimental culture medium for cultivation of Leishmania amazonensis: its efficacy for the continuous in vitro growth and differentiation of infective promastigote forms | 10.1007/s00436-010-1775-4 | 2010 |
Detection of matrix metallopeptidase-9-like proteins in Trypanosoma cruzi | 10.1016/j.exppara.2010.01.023 | 2010 |
Biological roles of peptidases in trypanosomatids | 10.2174/1874421401004010005 | 2010 |
HIV aspartyl protease inhibitors as promising compounds against Candida albicans | 10.4331/wjbc.v1.i2.21 | 2010 |
Phospholipase and esterase production by clinical strains of Fonsecaea pedrosoi and their interactions with epithelial cells | 10.1007/s11046-010-9293-6 | 2010 |
Effect of serine-type protease of Candida spp. isolated from linear gingival erythema of HIV-positive children: critical factors in the colonization | 10.1111/j.1600-0714.2010.00906.x | 2010 |
Effects of the calpain inhibitor MDL28170 on the clinical relevant forms of Trypanosoma cruzi in vitro | 10.1093/jac/dkq154 | 2010 |
Trypanosoma cruzi: ubiquity expression of surface cruzipain molecules in TCI and TCII field isolates | 10.1007/s00436-010-1888-9 | 2010 |
Proteomic analysis of two Trypanosoma cruzi zymodeme 3 strains | 10.1016/j.exppara.2010.06.005 | 2010 |
Influence of leishmanolysin-like molecules of Herpetomonas samuelpessoai on the interaction with macrophages | 10.1016/j.micinf.2010.07.010 | 2010 |
Proteins and peptidases from conidia and mycelia of Scedosporium apiospermum strain HLPB | 10.1007/s11046-008-9147-7 | 2009 |
Differential influence of gp63-like molecules in three distinct Leptomonas species on the adhesion to insect cells | 10.1007/s00436-008-1202-2 | 2009 |
Cysteine peptidases in Herpetomonas samuelpessoai are modulated by temperature and dimethylsulfoxide-triggered differentiation | 10.1017/S0031182008005209 | 2009 |
Biochemical characterization of potential virulence markers in the human fungal pathogen Pseudallescheria boydii | 10.1080/13693780802610305 | 2009 |
Roles of the endosymbiont and leishmanolysin-like molecules expressed by Crithidia deanei in the interaction with mammalian fibroblasts | 10.1016/j.exppara.2008.11.011 | 2009 |
Effect of chelating agents on the growth, surface polypeptide synthesis and interaction of Streptococcus agalactiae with human epithelial cells | 10.3892/mmr_00000065 | 2009 |
Arrested growth of Trypanosoma cruzi by the calpain inhibitor MDL28170 and detection of calpain homologues in epimastigote forms | 10.1017/S0031182009005629 | 2009 |
HIV aspartyl peptidase inhibitors interfere with cellular proliferation, ultrastructure and macrophage infection of Leishmania amazonensis | 10.1371/journal.pone.0004918 | 2009 |
Sialoglycoconjugates in Herpetomonas megaseliae: role in the adhesion to insect host epithelial cells | 10.1111/j.1574-6968.2009.01606.x | 2009 |
Bodo sp., a free-living flagellate, expresses divergent proteolytic activities from the closely related parasitic trypanosomatids | 10.1111/j.1550-7408.2009.00424.x | 2009 |
Trailing end-point phenotype antibiotic-sensitive strains of Candida albicans produce different amounts of aspartyl peptidases | 2009 | |
Major cysteine protease (cruzipain) in Z3 sylvatic isolates of Trypanosoma cruzi from Rio de Janeiro, Brazil | 10.1007/s00436-009-1446-5 | 2009 |
Dissimilar peptidase production by avirulent and virulent promastigotes of Leishmania braziliensis: inference on the parasite proliferation and interaction with macrophages | 10.1017/S0031182009990540 | 2009 |
Cysteine peptidases from Phytomonas serpens: biochemical and immunological approaches | 10.1111/j.1574-695X.2009.00604.x | 2009 |
Heterogeneous production of metallo-type peptidases in parasites belonging to the family Trypanosomatidae | 10.1016/j.ejop.2007.08.006 | 2008 |
Crithidia deanei: influence of parasite gp63 homologue on the interaction of endosymbiont-harboring and aposymbiotic strains with Aedes aegypti midgut | 10.1016/j.exppara.2007.09.007 | 2008 |
Analysis of peptidases in non-infected and Trypanosoma cruzi-infected mouse embryo hepatocyte cells | 2008 | |
Cellular localization and expression of gp63 homologous metalloproteases in Leishmania (Viannia) braziliensis strains | 10.1016/j.actatropica.2008.03.005 | 2008 |
A 25-kDa serine peptidase with keratinolytic activity secreted by Coccidioides immitis | 10.1007/s11046-008-9116-1 | 2008 |
Metallopeptidases produced by group B Streptococcus: influence of proteolytic inhibitors on growth and on interaction with human cell lineages | 2008 | |
Protease expression analysis in recently field-isolated strains of Trypanosoma cruzi: a heterogeneous profile of cysteine protease activities between TC I and TC II major phylogenetic groups | 10.1017/S0031182008004587 | 2008 |
Cysteine peptidases in the tomato trypanosomatid Phytomonas serpens: influence of growth conditions, similarities with cruzipain and secretion to the extracellular environment | 10.1016/j.exppara.2008.08.011 | 2008 |
Beneficial effects of HIV peptidase inhibitors on Fonsecaea pedrosoi: promising compounds to arrest key fungal biological processes and virulence | 10.1371/journal.pone.0003382 | 2008 |
Trypanosomatidae peptidases: a target for drugs development | 10.2174/157340807779815468 | 2007 |
Heparin binding proteins from Leishmania (Viannia) braziliensis promastigotes | 10.1016/j.vetpar.2006.12.019 | 2007 |
Phytomonas serpens: immunological similarities with the human trypanosomatid pathogens | 10.1016/j.micinf.2007.03.018 | 2007 |
Effect of sphingosine and phorbol-12-myristate-13-acetate on the growth and dimethylsulfoxide-induced differentiation in the insect trypanosomatid Herpetomonas samuelpessoai | 10.1590/S0074-02762007005000059 | 2007 |
Biology and pathogenesis of Fonsecaea pedrosoi, the major etiologic agent of chromoblastomycosis | 10.1111/j.1574-6976.2007.00077.x | 2007 |
Effect of suramin on the human pathogen Candida albicans: implications on the fungal development and virulence | 10.1111/j.1574-695X.2007.00321.x | 2007 |
Development of a ligand blot assay using biotinylated live cells | 10.1177/1087057107307146 | 2007 |
Extracellular peptidases in the fungal pathogen Pseudallescheria boydii | 10.1007/s00284-005-0156-1 | 2006 |
Leishmanolysin (gp63 metallopeptidase)-like activity extracellularly released by Herpetomonas samuelpessoai | 10.1017/S0031182005008802 | 2006 |
The major chromoblastomycosis fungal pathogen, Fonsecaea pedrosoi, extracellularly releases proteolytic enzymes whose expression is modulated by culture medium composition: implications on the fungal development and cleavage of key's host structures | 10.1111/j.1574-695X.2005.00003.x | 2006 |
Secretion of serine peptidase by a clinical strain of Candida albicans: influence of growth conditions and cleavage of human serum proteins and extracellular matrix components | 10.1111/j.1574-695X.2005.00023.x | 2006 |
Insights into the role of gp63-like proteins in lower trypanosomatids | 10.1111/j.1574-6968.2005.00022.x | 2006 |
Pseudallescheria boydii releases metallopeptidases capable of cleaving several proteinaceous compounds | 10.1016/j.resmic.2005.11.010 | 2006 |
Gp63-like molecules in Phytomonas serpens: possible role in the insect interaction | 10.1007/s00284-005-0222-8 | 2006 |
Trypanosoma rangeli: differential expression of cell surface polypeptides and ecto-phosphatase activity in short and long epimastigote forms | 10.1016/j.exppara.2005.11.015 | 2006 |
Peptidases and gp63-like proteins in Herpetomonas megaseliae: possible involvement in the adhesion to the invertebrate host | 10.1016/j.ijpara.2005.12.006 | 2006 |
The ubiquitous gp63-like metalloprotease from lower trypanosomatids: in the search for a function | 10.1590/S0001-37652006000400006 | 2006 |
Leishmania amazonensis: biological and biochemical characterization of ecto-nucleoside triphosphate diphosphohydrolase activities | 10.1016/j.exppara.2006.02.007 | 2006 |
Antileishmanial activity of MDL 28170, a potent calpain inhibitor | 10.1016/j.ijantimicag.2006.03.021 | 2006 |
Influence of growth conditions on the production of extracellular proteolytic enzymes in Paenibacillus peoriae NRRL BD-62 and Paenibacillus polymyxa SCE2 | 10.1111/j.1472-765X.2006.02015.x | 2006 |
Secretory aspartyl peptidase activity from mycelia of the human fungal pathogen Fonsecaea pedrosoi: effect of HIV aspartyl proteolytic inhibitors | 10.1016/j.resmic.2006.07.003 | 2006 |
Phytomonas serpens: cysteine peptidase inhibitors interfere with growth, ultrastructure and host adhesion | 10.1016/j.ijpara.2005.09.004 | 2006 |
Use of proteolytic enzymes as an additional tool for trypanosomatid identification | 10.1017/S0031182004006353 | 2005 |
Candida guilliermondii isolated from HIV-infected human secretes a 50 kDa serine proteinase that cleaves a broad spectrum of proteinaceous substrates | 10.1016/j.femsim.2004.06.022 | 2005 |
Proteolytic expression in Blastocrithidia culicis: influence of the endosymbiont and similarities with virulence factors of pathogenic trypanosomatids | 10.1017/S0031182004006705 | 2005 |
Production of antimicrobial substances by Bacillus subtilis LFE-1, B. firmus H2O-1 and B. licheniformis T6-5 isolated from an oil reservoir in Brazil | 10.1111/j.1365-2672.2004.02518.x | 2005 |
Influence of the endosymbiont of Blastocrithidia culicis and Crithidia deanei on the glycoconjugate expression and on Aedes aegypti interaction | 10.1016/j.femsle.2005.09.012 | 2005 |
Differential lectin recognition of glycoproteins in choanomastigote-shaped trypanosomatids: taxonomic implications | 10.1016/S0378-1097(03)00915-7 | 2004 |
Leishmanicidal activity of polyphenolic-rich extract from husk fiber of Cocos nucifera Linn. (Palmae) | 10.1016/j.resmic.2003.12.001 | 2004 |
Differential expression of sialylglycoconjugates and sialidase activity in distinct morphological stages of Fonsecaea pedrosoi | 10.1007/s00203-004-0653-9 | 2004 |
Involvement of peptidorhamnomannan in the interaction of Pseudallescheria boydii and HEp2 cells | 10.1016/j.micinf.2004.07.006 | 2004 |
Differential recovery of Candida species from subgingival sites in human immunodeficiency virus-positive and healthy children from Rio de Janeiro, Brazil | 10.1128/JCM.42.12.5925-5927.2004 | 2004 |
Herpetomonas samuelpessoai: dimethylsulfoxide-induced differentiation is influenced by proteinase expression | 10.1007/s00284-002-3795-5 | 2003 |
Heterogeneity of metallo and serine extracellular proteinases in oral clinical isolates of Candida albicans in HIV-positive and health children from Rio de Janeiro, Brazil | 10.1016/S0928-8244(03)00145-7 | 2003 |
Antimicrobial activity of Paenibacillus peoriae strain NRRL BD-62 against a broad spectrum of phytopathogenic bacteria and fungi | 10.1046/j.1365-2672.2003.02097.x | 2003 |
Leishmania (Leishmania) amazonensis: differential expression of proteinases and cell-surface polypeptides in avirulent and virulent promastigotes | 10.1016/S0014-4894(03)00135-8 | 2003 |
Activation of the glycosylphosphatidylinositol-anchored membrane proteinase upon release from Herpetomonas samuelpessoai by phospholipase C | 10.1007/s00284-002-3752-3 | 2002 |
Changes of sialomolecules during the dimethylsulfoxide-induced differentiation of Herpetomonas samuelpessoai | 10.1007/s00436-002-0685-5 | 2002 |
Secreted phosphatase activity induced by dimethyl sulfoxide in Herpetomonas samuelpessoai | S0 0 03 -9 8 61 (0 2 )0 04 0 3-4 | 2002 |
Detection of sialoglycomolecules in five plant trypanosomatids and in an insect phytophagous isolate | 2002 | |
Developmentally regulated protein expression mediated by dimethylsulfoxide in Herpetomonas samuelpessoai | 10.1007/s002840010188 | 2001 |
Cell-associated and extracellular proteinases in Blastocrithidia culicis: influence of growth conditions | 10.1007/s002840010269 | 2001 |
Characterization of proteinases in Herpetomonas anglusteri and Herpetomonas roitmani | 10.1007/s002849900418 | 1999 |
Detection and analysis of apoptosis in peripheral blood cells from breast cancer patients | 10.1590/S0100-879X1999000400004 | 1999 |
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