Ulisses Gazos Lopes
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Programa de Biologia Molecular e Estrutural/Biof
Formação:
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Institut Pasteur
| Pós-Doutorado | 2017 - 2018
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Harvard Medical School
| Pós-Doutorado | 1994 - 1996
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Genética) | Doutorado | 1982 - 1988
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Universidade Federal de Minas Gerais
Parasitologia | Mestrado | 1979 - 1982
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Universidade do Estado do Rio de Janeiro
Ciências Biológicas | Graduação | 1974 - 1977
Laboratórios:
Nuvens de Palavras:
Artigos:
(49.40% artigos com DOI)
Titulo | DOI | Ano |
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Activity of the Di-Substituted Urea-Derived Compound I-17 in Leishmania In Vitro Infections | 10.3390/pathogens13020104 | 2024 |
Inhibition of Microbicidal Activity of Canine Macrophages DH82 Cell Line by Capsular Polysaccharides from Cryptococcus neoformans | 10.3390/jof10050339 | 2024 |
TLR2, TLR4 and Protein kinase R (PKR) induced Type I Interferon sustains infection of Leishmania donovani in macrophages | 10.3389/fimmu.2022.801182 | 2022 |
Endoplasmic Stress Affects the Coinfection of Leishmania Amazonensis and the Phlebovirus (Bunyaviridae) Icoaraci | 10.3390/v14091948 | 2022 |
Toll-Like Receptor 3 (TLR3) Is Engaged in the Intracellular Survival of the Protozoan Parasite Leishmania (Leishmania) amazonensis | 10.1128/iai.00324-22 | 2022 |
The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism | 10.1371/journal.ppat.1009422 | 2021 |
Production, quantification, and infection of Amazonian Phlebovirus (Bunyaviridae) | 10.21769/BioProtoc.4072 | 2021 |
TLR-9 Plays a Role in Mycobacterium leprae-Induced Innate Immune Activation of A549 Alveolar Epithelial Cells | 10.3389/fimmu.2021.657449 | 2021 |
Intranasal immunization with chitosan microparticles enhances lack-dna vaccine protection and induces specific long-lasting immunity against visceral leishmaniasis | 10.1016/j.micinf.2021.104884 | 2021 |
The Potential Role of Nrf2 Signaling in Leishmania Infection Outcomes | 10.3389/fcimb.2019.00453 | 2020 |
RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages | 10.3389/fimmu.2020.00886 | 2020 |
DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis | 10.3389/fcimb.2020.00247 | 2020 |
Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis | 10.1371/journal.pntd.0007500 | 2019 |
Proteomic Analysis Reveals a Predominant NFE2L2 (NRF2) Signature in Canonical Pathway and Upstream Regulator Analysis of Leishmania-Infected Macrophages | 10.3389/fimmu.2019.01362 | 2019 |
Neutrophil elastase promotes infection interferon-β | 10.1096/fj.201900524R | 2019 |
Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation | 10.1038/s41598-018-23259-9 | 2018 |
Leishmania infantum Lipophosphoglycan-Deficient Mutants: A Tool to Study Host Cell-Parasite Interplay | 10.3389/fmicb.2018.00626 | 2018 |
Leishmania amazonensis downregulates macrophage iNOS expression via Histone | 10.1002/eji.201747257 | 2018 |
Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites | 10.3389/fimmu.2018.02779 | 2018 |
Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis | 10.3389/fimmu.2017.01127 | 2017 |
Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis | 10.1038/s41598-017-17252-x | 2017 |
Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages | 10.1038/srep27632 | 2016 |
Unveiling the Role of the Integrated Endoplasmic Reticulum Stress Response in Leishmania Infection - Future Perspectives | 10.3389/fimmu.2016.00283 | 2016 |
The human parasite Leishmania amazonensis downregulates iNOS expression via NF-κB p50/p50 homodimer: role of the PI3K/Akt pathway | 10.1098/rsob.150118 | 2015 |
Functional studies of TcRjl, a novel GTPase of Trypanosoma cruzi, reveals phenotypes related with MAPK activation during parasite differentiation and after heterologous expression in Drosophila model system | 10.1016/j.bbrc.2015.09.110 | 2015 |
HIV-1 Tat protein enhances the intracellular growth of Leishmania amazonensis via the ds-RNA induced protein PKR | 10.1038/srep16777 | 2015 |
The integrated endoplasmic reticulum stress response in Leishmania amazonensis macrophage infection: the role of X-box binding protein 1 transcription factor | 10.1096/fj.15-281550 | 2015 |
Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils | 10.1093/infdis/jiu158 | 2014 |
Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNF and IFN | 10.1096/fj.13-245126 | 2014 |
IL-27 enhances Leishmania amazonensis infection via ds-RNA dependent kinase (PKR) and IL-10 signaling | 10.1016/j.imbio.2014.11.006 | 2014 |
Detección y caracterización microbiológica de enterobacterias multidrogorresistentes transportadoras del gen modificador de aminoglicósidos durante tres décadas en un hospital universitario de Río de Janeiro | 10.7705/biomedica.v35i1.2276 | 2014 |
Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation | 10.1371/journal.pone.0076233 | 2013 |
A rapid and quantitative method for the evaluation of V gene usage, specificities and the clonal size of B cell repertoires | 10.1016/j.jim.2011.12.005 | 2012 |
The GTPase TcRjl of the human pathogen Trypanosoma cruzi is involved in the cell growth and differentiation | 10.1016/j.bbrc.2012.01.119 | 2012 |
A framework to identify gene expression profiles in a model of inflammation induced by lipopolysaccharide after treatment with thalidomide | 10.1186/1756-0500-5-292 | 2012 |
ExoU Activates NF-¿B and Increases IL-8/KC Secretion during Pseudomonas aeruginosa Infection | 10.1371/journal.pone.0041772 | 2012 |
Dolabelladienetriol, a Compound from Dictyota pfaffii Algae, Inhibits the Infection by Leishmania amazonensis | 10.1371/journal.pntd.0001787 | 2012 |
Peripheral expression of LACK-mRNA induced by intranasal vaccination with PCI-NEO-LACK defines the protection duration against murine visceral leishmaniasis | 2012 | |
Human cutaneous leishmaniasis: interferon-dependent expression of double-stranded RNA-dependent protein kinase (PKR) via TLR2 | 10.1096/fj.11-185165 | 2011 |
Intranasal immunization with LACK-DNA promotes protective immunity in hamsters challenged with Leishmania chagasi | 10.1017/S0031182011001417 | 2011 |
Thalidomide modulates Mycobacterium leprae-induced NF-¿B pathway and lower cytokine response | 10.1016/j.ejphar.2011.08.046 | 2011 |
Mycobacterium leprae induces insulin-like growth factor and promotes survival of Schwann cells upon serum withdrawal | 2010 | |
Inhibitory effect of the alkaloide warifteine purified from Cissampelos sympodiadis on B Lymphocyte function in vitro and in vivo | 2010 | |
Novel role for the double-strand RNA-activated protein kinase PKR: modulation of macropahge infection by the protozoan parasite Leishmania | 2010 | |
Heme Amplifies the Innate Immune Response to Microbial Molecules through Spleen Tyrosine Kinase (Syk)-dependent Reactive Oxygen Species Generation | 10.1074/jbc.M110.146076 | 2010 |
Modulation of in vitro murine B-lymphocyte response by curcumin | 2009 | |
NF-kB-mediated repression of iNOS expression in Leishmania amazonensis macrophage infection | 2009 | |
Evolutionary conservation of actin-binding proteins in Trypanosoma cruzi and unusual subcellular localization of the actin-binding homologue | 2008 | |
Intranasal delivery of naked DNA encoding the LACK antigen leads to protective immunity against visceral leishmaniasis | 2007 | |
The proteasome function is required for Mycobacterium leprae-induced apoptosis and citokine secretion | 2007 | |
Lysophosphatidylcholine produced by the phospholipase A(2) isolated from Laechis muta snake venom modulates natural killer activity as a protein kinase C effector | 2007 | |
Implications of oxidative stress in the cytotoxicity of Pseudomonas aeruginosa Exo U | 2006 | |
Thalidomide: an overview of its pharmacological mechanisms of action | 2006 | |
TcRho1, the Trypanosoma cruzi Rho homologue,regulates cell-adhesion properties: evidence for a conserved function | 2006 | |
DC-SIGN association with Th2 environment of lepromatous lesions: cause or effect? | 2006 | |
Cell structure and cytokinesis alterations in multidrug-resistant Leishmania (Leishmania) amazonensis | 2005 | |
The Transcription Factor NFAT3 Mediates Neuronal Cell Survival | 2005 | |
Caspase-8 Activity Prevents Type 2 Cytokine Responses and Is Required for Protective T Cell-Mediated Immunity against Trypanosoma cruzi Infection | 2005 | |
Mycobacterium leprae induces NF-kB dependent transcription repression in human Schwann cells | 2005 | |
Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU | 2005 | |
RJLs: a new family of Ras-related GTP-binding proteins | 2004 | |
Characterization of Trypanosoma cruzi TcRjl locus and analysis of its transcript | 2004 | |
The T-cell anergy induced by Leishmania amazonensis antigens is related with defective antigen presentation and apoptosis | 2004 | |
TcRho1of Trypanosoma cruzi: role in metacyclogenesis and cellular localization | 2004 | |
TcArf1: a Trypanosoma cruzi ADP-ribosylation factor | 2003 | |
Neurite outgrowth is impaired on HSP70-positive astrocytes through a mechanism that requires NF-kB activation | 2002 | |
TcRho1: a Rho family homologue from Trypanosoma cruzi: cloning, characterization and prenylation studies | 2001 | |
Characterization of a Rab 11 homologue gene in Trypanosoma cruzi | 2000 | |
Evidence of gentamicin resistance amplification in Klebsiella pneumoniae isolated from faeces of hospitalized newborns | 1999 | |
P53-Dependent Induction Of Apoptosis By Proteasome Inhibitors | 1997 | |
Leishmania braziliensis, Molecular Characterization Of The Elongation Factor I Alpha Gene | 1997 | |
An Oligonucleotide Probe Derived From kDNA Minirepeats For Leishmania (Viannia) | 1996 | |
Leishmania amazonensis: Multidrug Resistance In Vinblastine Resistant Promastigotes Is Associated With Rhodamine 123 Efflux, DNA Amplification And RNA Overexpression Of A Leishmania Mdr1 Gene | 1995 | |
Characterization Of Old World Leishmania Species Using Amplified Minicircle Variable Regions As Molecular Probes | 1995 | |
Comparison Of The Polymerase Chain Reaction And Serology For The Detection Of Canine Visceral Leishmaniasis | 1995 | |
The Identity Of Leishmania Isolated From Sandflies And Vertebarte Hosts In A Major Focus Of Cutaneous Leishmaniasis In Baturite, Brazil | 1994 | |
Use Of Molecular Probes And PCRFor The Detection And Typing Of Leishmania - A Mini-Review | 1994 | |
Detection of Trypanosoma cruzi and Leishmania using the Polymerase Chain Reaction | 1994 | |
Identification of GTPase Genes In The Protozoa Parasites Trypanosoma cruzi and Leishmania braziliensis | 1993 | |
Natural infection of Lutzomyia(Nyssomia) whitmani by Leishmania of the braziliensis complex in Baturité, Ceara State, northeast Brazil | 1990 | |
Canine Visceral leishmaniasis in northeast Brazil: assessment of serodiagnostic methods | 1990 | |
Identification of Visceral 'Leishmania' Species with Cloned Sequences of Kinetoplast DNA. | 1986 | |
Schizodeme And Zymodeme Characterization of 'Leishmania' in the Investigation of foci of visceral and cutaneous Leishmaniasis. | 1984 |
Eventos:
(0.00% eventos com DOI)