Ulisses Gazos Lopes

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biologia Molecular e Estrutural/Biof

ORCID:

não disponível no Lattes


Formação:
  • Institut Pasteur

    | Pós-Doutorado | 2017 - 2018
  • Harvard Medical School

    | Pós-Doutorado | 1994 - 1996
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Genética) | Doutorado | 1982 - 1988
  • Universidade Federal de Minas Gerais

    Parasitologia | Mestrado | 1979 - 1982
  • Universidade do Estado do Rio de Janeiro

    Ciências Biológicas | Graduação | 1974 - 1977
Laboratórios:
Nuvens de Palavras:
Artigos:

(49.40% artigos com DOI)

Titulo DOI Ano
Activity of the Di-Substituted Urea-Derived Compound I-17 in Leishmania In Vitro Infections 10.3390/pathogens13020104 2024
Inhibition of Microbicidal Activity of Canine Macrophages DH82 Cell Line by Capsular Polysaccharides from Cryptococcus neoformans 10.3390/jof10050339 2024
TLR2, TLR4 and Protein kinase R (PKR) induced Type I Interferon sustains infection of Leishmania donovani in macrophages 10.3389/fimmu.2022.801182 2022
Endoplasmic Stress Affects the Coinfection of Leishmania Amazonensis and the Phlebovirus (Bunyaviridae) Icoaraci 10.3390/v14091948 2022
Toll-Like Receptor 3 (TLR3) Is Engaged in the Intracellular Survival of the Protozoan Parasite Leishmania (Leishmania) amazonensis 10.1128/iai.00324-22 2022
The antioxidant response favors Leishmania parasites survival, limits inflammation and reprograms the host cell metabolism 10.1371/journal.ppat.1009422 2021
Production, quantification, and infection of Amazonian Phlebovirus (Bunyaviridae) 10.21769/BioProtoc.4072 2021
TLR-9 Plays a Role in Mycobacterium leprae-Induced Innate Immune Activation of A549 Alveolar Epithelial Cells 10.3389/fimmu.2021.657449 2021
Intranasal immunization with chitosan microparticles enhances lack-dna vaccine protection and induces specific long-lasting immunity against visceral leishmaniasis 10.1016/j.micinf.2021.104884 2021
The Potential Role of Nrf2 Signaling in Leishmania Infection Outcomes 10.3389/fcimb.2019.00453 2020
RANK Ligand Helps Immunity to Leishmania major by Skewing M2-Like Into M1 Macrophages 10.3389/fimmu.2020.00886 2020
DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis 10.3389/fcimb.2020.00247 2020
Amazonian Phlebovirus (Bunyaviridae) potentiates the infection of Leishmania (Leishmania) amazonensis: Role of the PKR/IFN1/IL-10 axis 10.1371/journal.pntd.0007500 2019
Proteomic Analysis Reveals a Predominant NFE2L2 (NRF2) Signature in Canonical Pathway and Upstream Regulator Analysis of Leishmania-Infected Macrophages 10.3389/fimmu.2019.01362 2019
Neutrophil elastase promotes infection interferon-β 10.1096/fj.201900524R 2019
Identification of di-substituted ureas that prevent growth of trypanosomes through inhibition of translation initiation 10.1038/s41598-018-23259-9 2018
Leishmania infantum Lipophosphoglycan-Deficient Mutants: A Tool to Study Host Cell-Parasite Interplay 10.3389/fmicb.2018.00626 2018
Leishmania amazonensis downregulates macrophage iNOS expression via Histone 10.1002/eji.201747257 2018
Lutzomyia longipalpis Saliva Induces Heme Oxygenase-1 Expression at Bite Sites 10.3389/fimmu.2018.02779 2018
Systems Approach Reveals Nuclear Factor Erythroid 2-Related Factor 2/Protein Kinase R Crosstalk in Human Cutaneous Leishmaniasis 10.3389/fimmu.2017.01127 2017
Emerging Role for the PERK/eIF2α/ATF4 in Human Cutaneous Leishmaniasis 10.1038/s41598-017-17252-x 2017
Mycobacterium leprae-induced Insulin-like Growth Factor I attenuates antimicrobial mechanisms, promoting bacterial survival in macrophages 10.1038/srep27632 2016
Unveiling the Role of the Integrated Endoplasmic Reticulum Stress Response in Leishmania Infection - Future Perspectives 10.3389/fimmu.2016.00283 2016
The human parasite Leishmania amazonensis downregulates iNOS expression via NF-κB p50/p50 homodimer: role of the PI3K/Akt pathway 10.1098/rsob.150118 2015
Functional studies of TcRjl, a novel GTPase of Trypanosoma cruzi, reveals phenotypes related with MAPK activation during parasite differentiation and after heterologous expression in Drosophila model system 10.1016/j.bbrc.2015.09.110 2015
HIV-1 Tat protein enhances the intracellular growth of Leishmania amazonensis via the ds-RNA induced protein PKR 10.1038/srep16777 2015
The integrated endoplasmic reticulum stress response in Leishmania amazonensis macrophage infection: the role of X-box binding protein 1 transcription factor 10.1096/fj.15-281550 2015
Understanding the mechanisms controlling Leishmania amazonensis infection in vitro: the role of LTB4 derived from human neutrophils 10.1093/infdis/jiu158 2014
Role of protein kinase R in the killing of Leishmania major by macrophages in response to neutrophil elastase and TLR4 via TNF  and IFN  10.1096/fj.13-245126 2014
IL-27 enhances Leishmania amazonensis infection via ds-RNA dependent kinase (PKR) and IL-10 signaling 10.1016/j.imbio.2014.11.006 2014
Detección y caracterización microbiológica de enterobacterias multidrogorresistentes transportadoras del gen modificador de aminoglicósidos durante tres décadas en un hospital universitario de Río de Janeiro 10.7705/biomedica.v35i1.2276 2014
Lysophosphatidylcholine Triggers TLR2- and TLR4-Mediated Signaling Pathways but Counteracts LPS-Induced NO Synthesis in Peritoneal Macrophages by Inhibiting NF-κB Translocation and MAPK/ERK Phosphorylation 10.1371/journal.pone.0076233 2013
A rapid and quantitative method for the evaluation of V gene usage, specificities and the clonal size of B cell repertoires 10.1016/j.jim.2011.12.005 2012
The GTPase TcRjl of the human pathogen Trypanosoma cruzi is involved in the cell growth and differentiation 10.1016/j.bbrc.2012.01.119 2012
A framework to identify gene expression profiles in a model of inflammation induced by lipopolysaccharide after treatment with thalidomide 10.1186/1756-0500-5-292 2012
ExoU Activates NF-¿B and Increases IL-8/KC Secretion during Pseudomonas aeruginosa Infection 10.1371/journal.pone.0041772 2012
Dolabelladienetriol, a Compound from Dictyota pfaffii Algae, Inhibits the Infection by Leishmania amazonensis 10.1371/journal.pntd.0001787 2012
Peripheral expression of LACK-mRNA induced by intranasal vaccination with PCI-NEO-LACK defines the protection duration against murine visceral leishmaniasis 2012
Human cutaneous leishmaniasis: interferon-dependent expression of double-stranded RNA-dependent protein kinase (PKR) via TLR2 10.1096/fj.11-185165 2011
Intranasal immunization with LACK-DNA promotes protective immunity in hamsters challenged with Leishmania chagasi 10.1017/S0031182011001417 2011
Thalidomide modulates Mycobacterium leprae-induced NF-¿B pathway and lower cytokine response 10.1016/j.ejphar.2011.08.046 2011
Mycobacterium leprae induces insulin-like growth factor and promotes survival of Schwann cells upon serum withdrawal 2010
Inhibitory effect of the alkaloide warifteine purified from Cissampelos sympodiadis on B Lymphocyte function in vitro and in vivo 2010
Novel role for the double-strand RNA-activated protein kinase PKR: modulation of macropahge infection by the protozoan parasite Leishmania 2010
Heme Amplifies the Innate Immune Response to Microbial Molecules through Spleen Tyrosine Kinase (Syk)-dependent Reactive Oxygen Species Generation 10.1074/jbc.M110.146076 2010
Modulation of in vitro murine B-lymphocyte response by curcumin 2009
NF-kB-mediated repression of iNOS expression in Leishmania amazonensis macrophage infection 2009
Evolutionary conservation of actin-binding proteins in Trypanosoma cruzi and unusual subcellular localization of the actin-binding homologue 2008
Intranasal delivery of naked DNA encoding the LACK antigen leads to protective immunity against visceral leishmaniasis 2007
The proteasome function is required for Mycobacterium leprae-induced apoptosis and citokine secretion 2007
Lysophosphatidylcholine produced by the phospholipase A(2) isolated from Laechis muta snake venom modulates natural killer activity as a protein kinase C effector 2007
Implications of oxidative stress in the cytotoxicity of Pseudomonas aeruginosa Exo U 2006
Thalidomide: an overview of its pharmacological mechanisms of action 2006
TcRho1, the Trypanosoma cruzi Rho homologue,regulates cell-adhesion properties: evidence for a conserved function 2006
DC-SIGN association with Th2 environment of lepromatous lesions: cause or effect? 2006
Cell structure and cytokinesis alterations in multidrug-resistant Leishmania (Leishmania) amazonensis 2005
The Transcription Factor NFAT3 Mediates Neuronal Cell Survival 2005
Caspase-8 Activity Prevents Type 2 Cytokine Responses and Is Required for Protective T Cell-Mediated Immunity against Trypanosoma cruzi Infection 2005
Mycobacterium leprae induces NF-kB dependent transcription repression in human Schwann cells 2005
Eicosanoid-mediated proinflammatory activity of Pseudomonas aeruginosa ExoU 2005
RJLs: a new family of Ras-related GTP-binding proteins 2004
Characterization of Trypanosoma cruzi TcRjl locus and analysis of its transcript 2004
The T-cell anergy induced by Leishmania amazonensis antigens is related with defective antigen presentation and apoptosis 2004
TcRho1of Trypanosoma cruzi: role in metacyclogenesis and cellular localization 2004
TcArf1: a Trypanosoma cruzi ADP-ribosylation factor 2003
Neurite outgrowth is impaired on HSP70-positive astrocytes through a mechanism that requires NF-kB activation 2002
TcRho1: a Rho family homologue from Trypanosoma cruzi: cloning, characterization and prenylation studies 2001
Characterization of a Rab 11 homologue gene in Trypanosoma cruzi 2000
Evidence of gentamicin resistance amplification in Klebsiella pneumoniae isolated from faeces of hospitalized newborns 1999
P53-Dependent Induction Of Apoptosis By Proteasome Inhibitors 1997
Leishmania braziliensis, Molecular Characterization Of The Elongation Factor I Alpha Gene 1997
An Oligonucleotide Probe Derived From kDNA Minirepeats For Leishmania (Viannia) 1996
Leishmania amazonensis: Multidrug Resistance In Vinblastine Resistant Promastigotes Is Associated With Rhodamine 123 Efflux, DNA Amplification And RNA Overexpression Of A Leishmania Mdr1 Gene 1995
Characterization Of Old World Leishmania Species Using Amplified Minicircle Variable Regions As Molecular Probes 1995
Comparison Of The Polymerase Chain Reaction And Serology For The Detection Of Canine Visceral Leishmaniasis 1995
The Identity Of Leishmania Isolated From Sandflies And Vertebarte Hosts In A Major Focus Of Cutaneous Leishmaniasis In Baturite, Brazil 1994
Use Of Molecular Probes And PCRFor The Detection And Typing Of Leishmania - A Mini-Review 1994
Detection of Trypanosoma cruzi and Leishmania using the Polymerase Chain Reaction 1994
Identification of GTPase Genes In The Protozoa Parasites Trypanosoma cruzi and Leishmania braziliensis 1993
Natural infection of Lutzomyia(Nyssomia) whitmani by Leishmania of the braziliensis complex in Baturité, Ceara State, northeast Brazil 1990
Canine Visceral leishmaniasis in northeast Brazil: assessment of serodiagnostic methods 1990
Identification of Visceral 'Leishmania' Species with Cloned Sequences of Kinetoplast DNA. 1986
Schizodeme And Zymodeme Characterization of 'Leishmania' in the Investigation of foci of visceral and cutaneous Leishmaniasis. 1984
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Using ANOVA do analyse thalidomide's molecular mechanisms in human PBMC microarrays 2008
Use of MAANOVA for detecting differentially expressed genes in genome-wide expression of human PBMC stimulated with Mycobacteryum leprae 2005
Ras-related GTPases of Trypanosoma cruzi: search for families and functions 2005
Publicações:
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