Vitor Hugo Pomin
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Bioquímica Médica
Departamento:
Programa de Glicobiologia
Formação:
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Complex Carbohydrate Research Center, University of Georgia
| Pós-Doutorado | 2008 - 2010
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Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 2005 - 2008
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Universidade Federal do Rio de Janeiro
Química Biológica | Mestrado | 2004 - 2005
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Universidade Federal do Rio de Janeiro
Licenciatura Em Ciencias Biologicas | Graduação | 1999 - 2003
Laboratórios:
Nuvens de Palavras:
Artigos:
(97.50% artigos com DOI)
Titulo | DOI | Ano |
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Characterization of Heparin?s Conformational Ensemble by Molecular Dynamics Simulations and Nuclear Magnetic Resonance Spectroscopy | 10.1021/acs.jctc.1c00760 | 2022 |
Safety and Pharmacokinetics of Intranasally Administered Heparin | 10.1007/s11095-022-03191-4 | 2022 |
Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties | 10.1016/j.jbc.2022.101856 | 2022 |
Antiviral activities of four marine sulfated glycans against adenovirus and human cytomegalovirus | 10.1016/j.antiviral.2021.105077 | 2021 |
Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives | 10.1128/JVI.01987-20 | 2021 |
Red Algal Sulfated Galactan Binds and Protects Neural Cells from HIV-1 gp120 and Tat | 10.3390/ph14080714 | 2021 |
Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection | 10.1016/j.jbc.2021.101207 | 2021 |
Biocompatibility and structural characterization of glycosaminoglycans isolated from heads of silver-banded whiting (Sillago argentifasciata Martin & Montalban 1935) | 10.1016/j.ijbiomac.2020.02.160 | 2020 |
Conformational properties of l-fucose and the tetrasaccharide building block of the sulfated l-fucan from Lytechinus variegatus | 10.1016/j.jsb.2019.107407 | 2020 |
Marine Antithrombotics | 10.3390/md18100514 | 2020 |
Saturation Transfer Difference in Characterization of Glycosaminoglycan-Protein Interactions | 10.1177/2472630320921130 | 2020 |
Chondroitin sulfate isolated from the secretion of the venom-producing parotoid gland of Brazilian bufonid | 10.1016/j.ijbiomac.2018.11.240 | 2019 |
Galactosaminoglycans: Medical Applications and Drawbacks | 10.3390/molecules24152803 | 2019 |
Immunomodulatory activity of β-glucan-containing exopolysaccharides from Auricularia auricular in phagocytes and mice infected with Cryptococcus neoformans | 10.1093/mmy/myz042 | 2019 |
Glycosaminoglycans and Proteoglycans | 10.3390/ph11010027 | 2018 |
Marine Carbohydrate-Based Compounds with Medicinal Properties | 10.3390/md16070233 | 2018 |
Anticoagulant and Antithrombotic Properties of Three Structurally Correlated Sea Urchin Sulfated Glycans and Their Low-Molecular-Weight Derivatives | 10.3390/md16090304 | 2018 |
Glycosaminoglycan-Protein Interactions by Nuclear Magnetic Resonance (NMR) Spectroscopy | 10.3390/molecules23092314 | 2018 |
Sulfated Glycans and Related Digestive Enzymes in the Zika Virus Infectivity: Potential Mechanisms of Virus-Host Interaction and Perspectives in Drug Discovery | 10.1155/2017/4894598 | 2017 |
The sea as a rich source of structurally unique glycosaminoglycans and mimetics | 10.3390/microorganisms5030051 | 2017 |
Sulfated glycans in HIV infection and therapy | 10.2174/1381612823666170127113958 | 2017 |
Synthetic oligosaccharide libraries and microarray technology: a powerful combination for the success of the current glycosaminoglycan interactomics | 10.1002/cmdc.201700620 | 2017 |
NMR structural biology of sulfated glycans | 10.1080/07391102.2016.1171165 | 2016 |
Paradigms in the structural biology of the mitogenic ternary complex FGF:FGFR:heparin | 10.1016/j.biochi.2016.05.017 | 2016 |
The contribution of Glycobiology to the Zika outbreak in the Americas | 10.1093/glycob/cww057 | 2016 |
Dual and Antagonic Therapeutic Effects of Sulfated Glycans | 10.1016/j.bmc.2016.07.037 | 2016 |
NMR-based conformation and dynamics of a tetrasaccharide-repeating sulfated fucan substituted by different counterions | 10.1002/bip.22922 | 2016 |
1H and 15N NMR Analyses on Heparin, Heparan Sulfates and Related Monosaccharides Concerning the Chemical Exchange Regime of the N-Sulfo-Glucosamine Sulfamate Proton | 10.3390/ph9030058 | 2016 |
Oligosaccharides from the 3-linked 2-sulfated alpha-L-fucan and alpha-L-galactan show similar conformations but different dynamics | 10.1093/glycob/cww080 | 2016 |
Keratan sulfate: An up-to-date review | 10.1016/j.ijbiomac.2014.08.029 | 2015 |
Sulfated glycans in inflammation | 10.1016/j.ejmech.2015.01.002 | 2015 |
Sulfated glycans in sea urchin fertilization | 10.1007/s10719-015-9573-y | 2015 |
Current structural biology of the heparin interactome | 10.1016/j.sbi.2015.05.007 | 2015 |
NMR Structural Determination of Unique Invertebrate Glycosaminoglycans Endowed with Medical Properties | 10.1016/j.carres.2015.05.004 | 2015 |
Phylogeny, Structure, Function, Biosynthesis and Evolution of Sulfated Galactose-Containing Glycans | 10.1016/j.ijbiomac.2015.12.035 | 2015 |
Medical Gains of Chondroitin Sulfate upon Fucosylation | 10.2174/0929867322666151020101335 | 2015 |
A Dilemma in the Glycosaminoglycan-Based Therapy: Synthetic or Naturally Unique Molecules? | 10.1002/med.21356 | 2015 |
Antimicrobial Sulfated Glycans: Structure and Function | 10.2174/1568026615666150605104444 | 2015 |
Marine Non-Glycosaminoglycan Sulfated Glycans as Potential Pharmaceuticals | 10.3390/ph8040848 | 2015 |
Holothurian Fucosylated Chondroitin Sulfate | 10.3390/md12010232 | 2014 |
Marine medicinal glycomics | 10.3389/fcimb.2014.00005 | 2014 |
Specific sulfation and glycosylationâ--a structural combination for the anticoagulation of marine carbohydrates | 10.3389/fcimb.2014.00033 | 2014 |
NMR-based dynamics of free glycosaminoglycans in solution | 10.1039/c4an00531g | 2014 |
Solution NMR conformation of glycosaminoglycans | 10.1016/j.pbiomolbio.2014.01.001 | 2014 |
Anticoagulant motifs of marine sulfated glycans | 10.1007/s10719-014-9530-1 | 2014 |
Structural and functional analyses of bovine and porcine intestinal heparins confirm they are different drugs | 10.1016/j.drudis.2014.07.004 | 2014 |
Sea, Carbohydrates and Clotting: A Triad on the Road of Drug Discovery | 10.2174/1389557514666140820121048 | 2014 |
Unique properties of human -defensin 6 (hBD6) and glycosaminoglycan complex: sandwich-like dimerization and competition with the chemokine receptor 2 (CCR2) binding site | 10.1074/jbc.m114.572529 | 2014 |
Structural and functional analyses of biosimilar enoxaparins available in Brazil | 10.1160/th14-05-0411 | 2014 |
Heparin-Binding Proteins (Chemokines and Defensins) and their Complexes with Glycosaminoglycans from the Solution NMR Perspective | 10.2174/138920371507140916145029 | 2014 |
Biological findings from the recent NMR-based studies of glycosaminoglycan-protein interactions | 10.1093/glycob/cwu065 | 2014 |
Impact of sulfation pattern on the conformation and dynamics of sulfated fucan oligosaccharides as revealed by NMR and MD | 10.1093/glycob/cwu184 | 2014 |
Current Status of Fucanomics and Galactanomics in Drug Discovery and Glycomics | 10.4172/2168-958X.1000104 | 2013 |
Testimonial to Journal of Glycobiology: a Significant Contribution of OMICS Publishing Group towards the Progress of Glycobiology and Glycomics | 2013 | |
Marine sulfated glycans with serpin-unrelated anticoagulant properties | 2013 | |
How to analyze the anticoagulant and antithrombotic mechanisms of action in fucanome and galactanome? | 10.1007/s10719-013-9509-3 | 2013 |
Is the antithrombotic effect of sulfated galactans independent of serpin? | 10.1111/jth.12448 | 2013 |
NMR Chemical Shifts in Structural Biology of Glycosaminoglycans | 10.1021/ac401791h | 2013 |
Advances in glycosaminoglycanomics by 15N-NMR spectroscopy | 10.1007/s00216-013-6803-7 | 2013 |
Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges | 10.3390/md10040793 | 2012 |
Exploiting enzyme specificities in digestions of chondroitin sulfates A and C: Production of well-defined hexasaccharides. | 10.1093/glycob/cws055 | 2012 |
Residual keratan sulfate in chondroitin sulfate formulations for oral administration | 10.1016/j.carbpol.2012.06.009 | 2012 |
Fucanomics and galactanomics: Current status in drug discovery, mechanisms of action and role of the well-defined structures | 10.1016/j.bbagen.2012.08.022 | 2012 |
Structure versus anticoagulant and antithrombotic actions of marine sulfated polysaccharides | 10.1590/S0102-695X2012005000068 | 2012 |
Fucanome and Galactanome: Marine Glycomics Contribution | 10.4172/2168-958X.1000101 | 2012 |
Recent Demands of Glycomics: Subprojects and the Role of New Journals | 10.4172/2168-958X.1000e102 | 2012 |
Current Glycomics? Approaches: Subprojects and Journals | 10.4172/2153-0637.1000e102 | 2012 |
LC-MS n Analysis of Isomeric Chondroitin Sulfate Oligosaccharides Using a Chemical Derivatization Strategy | 10.1007/s13361-011-0174-0 | 2011 |
Structural and functional insights into sulfated galactans: a systematic review | 10.1007/s10719-009-9251-z | 2010 |
Unique extracellular matrix heparan sulfate from the bivalve Nodipecten nodosus (Linnaeus, 1758) safely inhibits arterial thrombosis after photochemically induced endothelial lesion | 10.1074/jbc.M109.091546 | 2010 |
Effects of oversulfated and fucosylated chondroitin sulfates on coagulation. Challenges for the study of anticoagulant polysaccharides | 10.1160/TH09-10-0734 | 2010 |
Characterization of glycosaminoglycans by (15)n NMR spectroscopy and in vivo isotopic labeling | 10.1021/ac1001383 | 2010 |
An overview about the structure-function relationship of marine sulfated homopolysaccharides with regular chemical structures. | 10.1002/bip.21200 | 2009 |
A Unique 2-Sulfated {beta}-Galactan from the Egg Jelly of the Sea Urchin Glyptocidaris crenularis: CONFORMATION FLEXIBILITY VERSUS INDUCTION OF THE SPERM ACROSOME REACTION | 10.1074/jbc.M109.005702 | 2009 |
A preponderantly 4-sulfated, 3-linked galactan from the green alga Codium isthmocladum. | 10.1093/glycob/cwm139 | 2008 |
Structure, biology, evolution, and medical importance of sulfated fucans and galactans | 10.1093/glycob/cwn085 | 2008 |
The Hemolymph of the ascidian Styela plicata (Chordata-Tunicata) contains heparin inside basophil-like cells and a unique sulfated galactoglucan in the plasma | 10.1074/jbc.M604056200 | 2007 |
The renal clearance of dextran sulfate decreases in puromycin aminonucleoside-induced glomerulosclerosis: A puzzle observation. | 10.1016/j.cca.2007.05.013 | 2007 |
Mild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach for preparing tailored sulfated oligosaccharides. | 10.1093/glycob/cwj030 | 2005 |
Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity. | 10.1093/glycob/cwi021 | 2005 |
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