Vitor Hugo Pomin

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Glicobiologia

ORCID:

não disponível no Lattes


Formação:
  • Complex Carbohydrate Research Center, University of Georgia

    | Pós-Doutorado | 2008 - 2010
  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 2005 - 2008
  • Universidade Federal do Rio de Janeiro

    Química Biológica | Mestrado | 2004 - 2005
  • Universidade Federal do Rio de Janeiro

    Licenciatura Em Ciencias Biologicas | Graduação | 1999 - 2003
Laboratórios:
Nuvens de Palavras:
Artigos:

(97.50% artigos com DOI)

Titulo DOI Ano
Characterization of Heparin?s Conformational Ensemble by Molecular Dynamics Simulations and Nuclear Magnetic Resonance Spectroscopy 10.1021/acs.jctc.1c00760 2022
Safety and Pharmacokinetics of Intranasally Administered Heparin 10.1007/s11095-022-03191-4 2022
Fractionation of sulfated galactan from the red alga Botryocladia occidentalis separates its anticoagulant and anti-SARS-CoV-2 properties 10.1016/j.jbc.2022.101856 2022
Antiviral activities of four marine sulfated glycans against adenovirus and human cytomegalovirus 10.1016/j.antiviral.2021.105077 2021
Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives 10.1128/JVI.01987-20 2021
Red Algal Sulfated Galactan Binds and Protects Neural Cells from HIV-1 gp120 and Tat 10.3390/ph14080714 2021
Structural and kinetic analyses of holothurian sulfated glycans suggest potential treatment for SARS-CoV-2 infection 10.1016/j.jbc.2021.101207 2021
Biocompatibility and structural characterization of glycosaminoglycans isolated from heads of silver-banded whiting (Sillago argentifasciata Martin & Montalban 1935) 10.1016/j.ijbiomac.2020.02.160 2020
Conformational properties of l-fucose and the tetrasaccharide building block of the sulfated l-fucan from Lytechinus variegatus 10.1016/j.jsb.2019.107407 2020
Marine Antithrombotics 10.3390/md18100514 2020
Saturation Transfer Difference in Characterization of Glycosaminoglycan-Protein Interactions 10.1177/2472630320921130 2020
Chondroitin sulfate isolated from the secretion of the venom-producing parotoid gland of Brazilian bufonid 10.1016/j.ijbiomac.2018.11.240 2019
Galactosaminoglycans: Medical Applications and Drawbacks 10.3390/molecules24152803 2019
Immunomodulatory activity of β-glucan-containing exopolysaccharides from Auricularia auricular in phagocytes and mice infected with Cryptococcus neoformans 10.1093/mmy/myz042 2019
Glycosaminoglycans and Proteoglycans 10.3390/ph11010027 2018
Marine Carbohydrate-Based Compounds with Medicinal Properties 10.3390/md16070233 2018
Anticoagulant and Antithrombotic Properties of Three Structurally Correlated Sea Urchin Sulfated Glycans and Their Low-Molecular-Weight Derivatives 10.3390/md16090304 2018
Glycosaminoglycan-Protein Interactions by Nuclear Magnetic Resonance (NMR) Spectroscopy 10.3390/molecules23092314 2018
Sulfated Glycans and Related Digestive Enzymes in the Zika Virus Infectivity: Potential Mechanisms of Virus-Host Interaction and Perspectives in Drug Discovery 10.1155/2017/4894598 2017
The sea as a rich source of structurally unique glycosaminoglycans and mimetics 10.3390/microorganisms5030051 2017
Sulfated glycans in HIV infection and therapy 10.2174/1381612823666170127113958 2017
Synthetic oligosaccharide libraries and microarray technology: a powerful combination for the success of the current glycosaminoglycan interactomics 10.1002/cmdc.201700620 2017
NMR structural biology of sulfated glycans 10.1080/07391102.2016.1171165 2016
Paradigms in the structural biology of the mitogenic ternary complex FGF:FGFR:heparin 10.1016/j.biochi.2016.05.017 2016
The contribution of Glycobiology to the Zika outbreak in the Americas 10.1093/glycob/cww057 2016
Dual and Antagonic Therapeutic Effects of Sulfated Glycans 10.1016/j.bmc.2016.07.037 2016
NMR-based conformation and dynamics of a tetrasaccharide-repeating sulfated fucan substituted by different counterions 10.1002/bip.22922 2016
1H and 15N NMR Analyses on Heparin, Heparan Sulfates and Related Monosaccharides Concerning the Chemical Exchange Regime of the N-Sulfo-Glucosamine Sulfamate Proton 10.3390/ph9030058 2016
Oligosaccharides from the 3-linked 2-sulfated alpha-L-fucan and alpha-L-galactan show similar conformations but different dynamics 10.1093/glycob/cww080 2016
Keratan sulfate: An up-to-date review 10.1016/j.ijbiomac.2014.08.029 2015
Sulfated glycans in inflammation 10.1016/j.ejmech.2015.01.002 2015
Sulfated glycans in sea urchin fertilization 10.1007/s10719-015-9573-y 2015
Current structural biology of the heparin interactome 10.1016/j.sbi.2015.05.007 2015
NMR Structural Determination of Unique Invertebrate Glycosaminoglycans Endowed with Medical Properties 10.1016/j.carres.2015.05.004 2015
Phylogeny, Structure, Function, Biosynthesis and Evolution of Sulfated Galactose-Containing Glycans 10.1016/j.ijbiomac.2015.12.035 2015
Medical Gains of Chondroitin Sulfate upon Fucosylation 10.2174/0929867322666151020101335 2015
A Dilemma in the Glycosaminoglycan-Based Therapy: Synthetic or Naturally Unique Molecules? 10.1002/med.21356 2015
Antimicrobial Sulfated Glycans: Structure and Function 10.2174/1568026615666150605104444 2015
Marine Non-Glycosaminoglycan Sulfated Glycans as Potential Pharmaceuticals 10.3390/ph8040848 2015
Holothurian Fucosylated Chondroitin Sulfate 10.3390/md12010232 2014
Marine medicinal glycomics 10.3389/fcimb.2014.00005 2014
Specific sulfation and glycosylationâ--a structural combination for the anticoagulation of marine carbohydrates 10.3389/fcimb.2014.00033 2014
NMR-based dynamics of free glycosaminoglycans in solution 10.1039/c4an00531g 2014
Solution NMR conformation of glycosaminoglycans 10.1016/j.pbiomolbio.2014.01.001 2014
Anticoagulant motifs of marine sulfated glycans 10.1007/s10719-014-9530-1 2014
Structural and functional analyses of bovine and porcine intestinal heparins confirm they are different drugs 10.1016/j.drudis.2014.07.004 2014
Sea, Carbohydrates and Clotting: A Triad on the Road of Drug Discovery 10.2174/1389557514666140820121048 2014
Unique properties of human  -defensin 6 (hBD6) and glycosaminoglycan complex: sandwich-like dimerization and competition with the chemokine receptor 2 (CCR2) binding site 10.1074/jbc.m114.572529 2014
Structural and functional analyses of biosimilar enoxaparins available in Brazil 10.1160/th14-05-0411 2014
Heparin-Binding Proteins (Chemokines and Defensins) and their Complexes with Glycosaminoglycans from the Solution NMR Perspective 10.2174/138920371507140916145029 2014
Biological findings from the recent NMR-based studies of glycosaminoglycan-protein interactions 10.1093/glycob/cwu065 2014
Impact of sulfation pattern on the conformation and dynamics of sulfated fucan oligosaccharides as revealed by NMR and MD 10.1093/glycob/cwu184 2014
Current Status of Fucanomics and Galactanomics in Drug Discovery and Glycomics 10.4172/2168-958X.1000104 2013
Testimonial to Journal of Glycobiology: a Significant Contribution of OMICS Publishing Group towards the Progress of Glycobiology and Glycomics 2013
Marine sulfated glycans with serpin-unrelated anticoagulant properties 2013
How to analyze the anticoagulant and antithrombotic mechanisms of action in fucanome and galactanome? 10.1007/s10719-013-9509-3 2013
Is the antithrombotic effect of sulfated galactans independent of serpin? 10.1111/jth.12448 2013
NMR Chemical Shifts in Structural Biology of Glycosaminoglycans 10.1021/ac401791h 2013
Advances in glycosaminoglycanomics by 15N-NMR spectroscopy 10.1007/s00216-013-6803-7 2013
Fucanomics and Galactanomics: Marine Distribution, Medicinal Impact, Conceptions, and Challenges 10.3390/md10040793 2012
Exploiting enzyme specificities in digestions of chondroitin sulfates A and C: Production of well-defined hexasaccharides. 10.1093/glycob/cws055 2012
Residual keratan sulfate in chondroitin sulfate formulations for oral administration 10.1016/j.carbpol.2012.06.009 2012
Fucanomics and galactanomics: Current status in drug discovery, mechanisms of action and role of the well-defined structures 10.1016/j.bbagen.2012.08.022 2012
Structure versus anticoagulant and antithrombotic actions of marine sulfated polysaccharides 10.1590/S0102-695X2012005000068 2012
Fucanome and Galactanome: Marine Glycomics Contribution 10.4172/2168-958X.1000101 2012
Recent Demands of Glycomics: Subprojects and the Role of New Journals 10.4172/2168-958X.1000e102 2012
Current Glycomics? Approaches: Subprojects and Journals 10.4172/2153-0637.1000e102 2012
LC-MS n Analysis of Isomeric Chondroitin Sulfate Oligosaccharides Using a Chemical Derivatization Strategy 10.1007/s13361-011-0174-0 2011
Structural and functional insights into sulfated galactans: a systematic review 10.1007/s10719-009-9251-z 2010
Unique extracellular matrix heparan sulfate from the bivalve Nodipecten nodosus (Linnaeus, 1758) safely inhibits arterial thrombosis after photochemically induced endothelial lesion 10.1074/jbc.M109.091546 2010
Effects of oversulfated and fucosylated chondroitin sulfates on coagulation. Challenges for the study of anticoagulant polysaccharides 10.1160/TH09-10-0734 2010
Characterization of glycosaminoglycans by (15)n NMR spectroscopy and in vivo isotopic labeling 10.1021/ac1001383 2010
An overview about the structure-function relationship of marine sulfated homopolysaccharides with regular chemical structures. 10.1002/bip.21200 2009
A Unique 2-Sulfated {beta}-Galactan from the Egg Jelly of the Sea Urchin Glyptocidaris crenularis: CONFORMATION FLEXIBILITY VERSUS INDUCTION OF THE SPERM ACROSOME REACTION 10.1074/jbc.M109.005702 2009
A preponderantly 4-sulfated, 3-linked galactan from the green alga Codium isthmocladum. 10.1093/glycob/cwm139 2008
Structure, biology, evolution, and medical importance of sulfated fucans and galactans 10.1093/glycob/cwn085 2008
The Hemolymph of the ascidian Styela plicata (Chordata-Tunicata) contains heparin inside basophil-like cells and a unique sulfated galactoglucan in the plasma 10.1074/jbc.M604056200 2007
The renal clearance of dextran sulfate decreases in puromycin aminonucleoside-induced glomerulosclerosis: A puzzle observation. 10.1016/j.cca.2007.05.013 2007
Mild acid hydrolysis of sulfated fucans: a selective 2-desulfation reaction and an alternative approach for preparing tailored sulfated oligosaccharides. 10.1093/glycob/cwj030 2005
Selective cleavage and anticoagulant activity of a sulfated fucan: stereospecific removal of a 2-sulfate ester from the polysaccharide by mild acid hydrolysis, preparation of oligosaccharides, and heparin cofactor II-dependent anticoagulant activity. 10.1093/glycob/cwi021 2005
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