Narcisa Leal da Cunha e Silva

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biofísica/I Biof

ORCID:

https://orcid.org/0000-0003-4863-4945


Formação:

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1984 - 1993

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Mestrado | 1980 - 1983

  • Universidade Federal do Rio de Janeiro

    Instituto de Biologia | Graduação | 1976 - 1979
Laboratórios:
Nuvens de Palavras:
Artigos:

(54.29% artigos com DOI)

Titulo DOI Ano
Paracrine Signaling Mediated by the Cytosolic Tryparedoxin Peroxidase of Trypanosoma cruzi 10.3390/pathogens13010067 2024
Iron Uptake Controls Trypanosoma cruzi Metabolic Shift and Cell Proliferation 10.3390/antiox12050984 2023
An Iron Transporter Is Involved in Iron Homeostasis, Energy Metabolism, Oxidative Stress, and Metacyclogenesis in Trypanosoma cruzi 10.3389/fcimb.2021.789401 2022
The cytostome-cytopharynx complex of intracellular and extracellular amastigotes of exhibit structural and functional differences 10.1111/cmi.13346 2021
Dynamics of the orphan myosin MyoF over Trypanosoma cruzi life cycle and along the endocytic pathway 10.1016/j.parint.2021.102444 2021
Trypanosomatid Flagellar Pocket from Structure to Function 10.1016/j.pt.2020.11.005 2021
Control of assembly of extra-axonemal structures: the paraflagellar rod of trypanosomes 10.1242/jcs.242271 2020
Electron microscopy cytochemistry and three-dimensional reconstruction of labeled structures in Trypanosoma cruzi 10.1007/s00436-020-06798-x 2020
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers 10.1074/jbc.m117.807180 2018
Tridimensional Electron Microscopy Analysis of the Early Endosomes and Endocytic Traffic in Trypanosoma cruzi Epimastigotes 10.1016/j.protis.2018.09.004 2018
Trypanosoma cruzi epimastigotes store cholesteryl esters in lipid droplets after cholesterol endocytosis 10.1016/j.molbiopara.2018.07.004 2018
Lysosome-like compartments of Trypanosoma cruzi trypomastigotes may originate directly from epimastigote reservosomes 10.1017/S0031182016002602 2017
The cytostome-cytopharynx complex of Trypanosoma cruzi epimastigotes disassembles during cell division 10.1242/jcs.187419 2017
An evaluation of lipid metabolism in the insect trypanosomatid Herpetomonas muscarum uncovers a pathway for the uptake of extracellular insect lipoproteins 10.1016/j.parint.2017.10.013 2017
Loss of the cytostome-cytopharynx and endocytic ability are late events in Trypanosoma cruzi metacyclogenesis 10.1016/j.jsb.2016.07.018 2016
Lipophorin Drives Lipid Incorporation and Metabolism in Insect Trypanosomatids 10.1016/j.protis.2015.04.003 2015
Trypanosoma cruzi Epimastigotes Are Able to Manage Internal Cholesterol Levels under Nutritional Lipid Stress Conditions 10.1371/journal.pone.0128949 2015
99m-Technetium binding site in bone marrow mononuclear cells 10.1186/s13287-015-0107-0 2015
The three-dimensional structure of the cytostome-cytopharinx complex of Trypanosoma cruzi epimastigotes 10.1242/jcs.135491 2014
Expression and cellular trafficking of GP82 and GP90 glycoproteins during Trypanosoma cruzi metacyclogenesis 10.1186/1756-3305-6-127 2013
Assembly of the Leishmania amazonensis flagellum during cell differentiation 10.1016/j.jsb.2013.09.006 2013
LDL uptake by Leishmania amazonensis: Involvement of membrane lipid microdomains 10.1016/j.exppara.2012.02.014 2012
On the ultrastructural organization of Trypanosoma cruzi using cryopreparation methods and electron tomography 10.1007/s00418-012-1002-8 2012
Trypanosoma cruzi Epimastigotes Are Able to Store and Mobilize High Amounts of Cholesterol in Reservosome Lipid Inclusions 10.1371/journal.pone.0022359 2011
Endocytosis in Trypanosoma cruzi 10.2174/1874421401004010098 2010
Attachment of flagellum to the cell body is important to the kinetics of transferrin uptake by Trypanosoma cruzi 10.1016/j.parint.2010.07.005 2010
Subcellular proteomics of Trypanosoma cruzi reservosomes 10.1002/pmic.200800730 2009
Electron microscopy and cytochemistry analysis of the endocytic pathway of pathogenic protozoa 10.1016/j.proghi.2009.01.001 2009
Trypanosoma cruzi: parasite shed vesicles increase heart parasitism and generate an intense inflammatory response 10.1016/j.micinf.2008.10.003 2009
Glucose uptake in the mammalian stages of Trypanosoma cruzi 10.1016/j.molbiopara.2009.07.006 2009
Sorting of phosphoglucomutase to glycosomes in Trypanosoma cruzi is mediated by an internal domain 10.1093/glycob/cwp121 2009
Cell Fractionation of Parasitic Protozoa 10.1007/978-1-60327-210-0 2008
Evolutionary conservation of actin-binding proteins in Trypanosoma cruzi and unusual subcellular localization of the actin homologue. 10.1017/S0031182008004496 2008
Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells. 10.1074/jbc.M802102200 2008
All Trypanosoma cruzi developmental forms present lysosome-related organelles 10.1007/s00418-008-0486-8 2008
New insights into the morphology of Trypanosoma cruzi reservosome 10.1002/jemt.20592 2008
Heme requirement and intracellular trafficking in Trypanosoma cruzi epimastigotes 10.1016/j.bbrc.2006.12.238 2007
Biochemical properties of the major proteins from Rhodnius prolixus eggshell 10.1016/j.ibmb.2007.07.010 2007
Platelet-activating factor-like activity isolated from Trypanosoma cruzi. 2006
Reservosomes: multipurpose organelles? 2006
Chagasin, the endogenous cysteine-protease inhibitor of Trypanosoma cruzi, modulates parasite differentiation and invasion of mammalian cells. 2005
Characterization of a RAB5 homologue in Trypanosoma cruzi 2005
Cryptic paraflagellar rod in endosymbiont-containing kinetoplastid protozoa 2005
Role for a P-type H +-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi. 2005
Improvement on the visualization of cytoskeletal structures of protozoan parasites using high-resolution field emission scanning electron microscopy (FESEM). 2005
Characterization of RAB-like4, the first identified RAB-like protein from Trypanosoma cruzi with GTPase activity. 2005
Biogenesis of reservosomes of Trypanosoma cruzi epimastigotes 2004
TcRho1 of Trypanosoma cruzi: role in metacyclogenesis and cellular localization 2004
Trypanosoma cruzi: TcRAB7 protein is localized at the Golgi apparatus in epimastigotes. 2004
Further studies on the structural analysis of the cuticle of Litomosoides chagasfilhoi (Nematoda: Filarioidea). 2003
Cell Fractionation of parasitic Protozoa - a review 2003
Trypanosoma rangeli uptakes the main lipoprotein from the hemolymph of its invertebrate host 2003
Expression and processing of megasome cysteine proteinases during Leishmania amazonensis differentiation 2002
Leishmania (Viannia) braziliensis metacyclic promastigotes purified using Bauhinia purpurea lectin are complement resistant and highly infective for macrophages in vitro and hamsters in vivo 2002
Isolation and characterization of a reservosome fraction from Trypanosoma cruzi. 2002
Cellular Signaling during the Macrophage Invasion by Trypanosoma cruzi 2002
Trypanosoma Cruzi Epimastigotes Endocytic Pathway: Cargo Enters The Cytostome And Passes Through An Early Endosomal Network Before Reservome Storage. 2000
Characterization Of A Rab11 Homologue In Trypanosoma Cruzi. 2000
Synthesis of vitellogenin by the follicle cells of Rhodnius prolixus 2000
Choline acetyltransferase detection in normal and denervated organ from Electrophorus electricus (L.) using a confocal scanning optical microscopy analysis. 2000
Two special organelles found in Trypanosoma cruzi. 2000
Purification Of The Paraflagellar Rod Of The Trypanosomatid Herpetomonas Megaseliae Allows The Identification Of Some Of Its Minor Components 1999
Tyrosine Phosphorylation Regulates Leishmania Invasion And Survival Within The Host Cell. 1996
Isolation and Biochemical Characterization of the costa of Tritrichomonas foetus 1993
Acetylated alpha tubulin in Trypanosoma cruzi: immunocytochemical localization 1993
Identification and localization of antigens in isolates of trypanosomatids of the genus Phytomonas 1992
Isolation and Characterization of a highly purified flagellar membrane fraction from trypanosomatids 1989
Localization Of Acetylated Alpha Tubulin In Tritrichomonas Foetus And Tritrichomonas Vaginalis. 1988
Tritrichomonas Foetus: Ultrastructure And Cytochemistry Of Endocytosis 1986
Isolation Of Flagellum And Characterization Of The Paraxial Structure Of Herpetomonas Megaseliae. 1984
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
THE INFLUENCE OF THE CYTOSKELETON ON TRYPANOSOMA CRUZI EPIMASTIGOTE ENDOCYTOSIS 2003
CHARACTERIZATION OF UBIQUITIN-ASSOCIATED VITELLIN POPULATIONS FROM RHODNIUS PROLIXUS 2003
HEME REQUIREMENT AND ITS POSSIBLE INTRACELLULAR TRAFFIC IN TRYPANOSOMA CRUZI EPIMASTIGOTES. 2003
THE CYTOSKELETON PARTICIPATES ON TRYPANOSOMA CRUZI EPIMASTIGOTES ENDOCYTIC PATHWAY 2003
DIVIDING LEISHMANIA (L.) AMAZONENSIS AND HERPETOMONAS MEGASELIAE PRESENT A FLAGELLA CONNECTOR 2003
ISOLATION OF LIPID DOMAINS FROM THE MEMBRANES OF TRYPANOSOMA CRUZI RESERVOSOMES 2003
Do reservosomes possess internal membranes? 2002
The influence of the cytoskeleton on Trypanosoma cruzi epimastigotes endocytosis 2002
Further studies concerning PFR genes and proteins in endosymbiont bearing trypanosomatids. 2002
TcRABs fused to GFP - an alternative strategy to study the location of TcRAB7 and TcRab5A proteins in Trypanosoma cruzi. 2002
Characterization of the first RAB-like gene in Trypanosma cruzi with mRNA expression alteration during endocytosis 2002
Lipid Transfer from Rhodnius prolixus to Trypanosoma cruzi 2002
Functional studies of the TcRho1 GTPase of Trypanosma cruzi 2002
HIGH RESOLUTION FIELD EMISSION SCANNING ELECTRON MICROSCOPE AS A TOOL FOR STUDIES ON THE CYTOSKELETON OF TRYPANOSOMATIDS. 2001
The Trypanosoma cruzi epimastigote transferrin-binding protein: identification of some putative candidates after a preliminary purification. 2001
Biogenesis of reservosomes in epimastigote forms of Trypanosoma cruzi recently differentiated from metacyclic trypomastigotes. 2001
The Presence of Paraflagellar Rod Genes in Trypanosomatids lacking the Paraflagellar Rod Structure. 2001
Lipid delivery to trypanosomatids by invertebrate host lipoprotein: intracellular localization 2001
Analysis of expression and cellular localization of the small GTPase TcRho1 in Trypanosoma cruzi. 2001
Biochemical characterization of a purified reservosome fraction from Trypanosoma cruzi. 2000
TcRAB5 and TcRab7 genes: possible new markers of early endosomes and Golgi in Trypanosoma cruzi. 2000
Metacyclogenesis of Leishmania amazonensis: a new world species 2000
Initial studies concerning the protein-filament correlation in the paraflagellar rod. 2000
Initial studies concerning the protein-filament correlation in the paraflagellar rod. 2000
Evidence that phospholipase A2 (PLA2) activity is required for fusion of intracelular membrane-bound compartments in Trypanosoma cruzi. 2000
Tcrab11 Functional Studies: A Putative Reservosome Marker In Trypanosoma Cruzi. 1999
Study Of Localization And Functional Aspects Of Trypanosoma Cruzi Rab7 Protein. 1999
Análise da colina acetil transferase em diferentes períodos de desnervação 1999
An acidic vesicle-tubular network is the early endosome of Trypanosoma cruzi 1999
Characterization of three rab genes in Trypanosoma cruzi 1999
Characterization of a Rab 11 homologue in Trypanosoma cruzi 1999
An acidic vesicle tubular network is the early endosome of Trypanosoma cruzi 1999
Preliminary Biochemical Analysis Of A Purified Paraflagellar Rod Fraction 1998
Obtention Of A Purified Sub-Cellular Fraction Containing Reservosomes Of Trypanosoma Cruzi. 1998
Trypanosoma Cruzi Epimastigotes Endocytic Pathway: Cargo Enters The Cytostome And Passes Through An Early Endosomal Network Before Reservome Storage. 1998
Studies Of Subcellular Localization Of Rab7 In Trypanosoma Cruzi. 1997
Protein Phosphorylation On The Interaction Process Of Macrophages With Tachyzoite Forms Of Toxoplasma Gondii.Ferreira, 1997
Immunocytochemical Studies On The Paraflagellar Rod Of The Trypanosomatid Herpetomonas Megaseliae. 1997
Additional Studies On The Reservosomes Of Trypanosoma Cruzi. 1997
RAB7 protein in Trypanosoma cruzi : approaches to study its function and localization. 1996
Tyrosine-phosphorylated proteins are present in Trypanosoma cruzi reservosomes 1996
Can Leishmania Amastigotes Subvert The Signaling Pathways Exploited by Other Pathogens? 1996
Resultados preliminares sobre o isolamento de reservossomos de epimastigotas de Trypanosoma cruzi. 1996
Estudos adicionais sobre a estrutura paraxial de Tripanosomatídeos 1996
Isolamento e Purificação Parcial dos Flagelos Anteriores de Tritrichomonas foetus. 1996
Protein phosphorylation is involved on the invasion process of macrophages by Trypanosoma cruzi and is associated with actin polymerization. 1995
Localization and Identification of a novel paraxial rod antigen. 1995
Parasite signal transduction regulates the transferrin endocytosis by Leishmania amazonensis promastigotes. 1995
Detection of phosphorylated tyrosine residues during the Leishmania amazonensis - host cell interaction. 1994
Isolation and Partial characterization of a Golgi-complex- enriched fraction from Tritrichomonas foetus. 1994
Morphological and growth variation of Phytomonas isolates cultivated in different media. 1994
Receptor mediated endocytosis and uptake of transferrin by Trypanosoma cruzi. 1993
Trypanosoma cruzi: Identification and localization of the LDL receptor. 1993
Quantitative evaluation of endocytosis of transferrin by Trypanosoma cruzi. 1992
The occurrence of L-fucose residues on the cell surface of trichomonads and their involvement in cell adhesion. 1992
Endocytosis of peroxidase by the epimastigote form of Trypanosoma cruzi: a quantitative study. 1991
Peritoneal mice macrophage fractionated on discontinuous Percoll gradient behave differently when infected with Leishmania amazonensis promastigotes. 1991
Preliminary results on the isolation of the costae of Trichomonads. 1990
Enolase activity in the electrocyte of Electrophorus electricus (L). 1989
Immunocytochemical analysis of five isolates of the genus Phytomonas. 1989
Preliminary analysis of the composition of the flagellar membrane from Trypanosomatids. 1989
Immunocytochemical localization of the acetylated alpha tubulin in trophozoites of Giardia lamblia. 1988
Preliminary analysis of the composition of the flagellar membrane of Herpetomonas samuelpessoai. CUNHA E SILVA. N.L. & De Souza, W. - Memórias do Instituto Oswaldo Cruz, suppl. vol.83, pg. 84, 1988. 1988
Immunocytochemical localization of acetylated alpha tubulin in Tritrichomonas foetus and Trichomonas vaginalis. 1987
Cytochemical detection of alpha tubulin in Trypanosoma cruzi. CUNHA E SILVA, N.L.; Souto-Padrón, T.; Piperno, G. & De Souza, W. - Memórias do Instituto OswaldoCruz, suppl. vol.82, pg. 74, 1987. 1987
The cytoskeleton of Tritrichomonas foetus. 1986
Preliminary characterization of the flagellar membrane fraction of Trypanosoma cruzi epimastigote. 1986
Citoesqueleto de Trypanosoma cruzi, estudos preliminares. 1985
Estudo citoquímico e ultraestrutural do processo de endocitose em Tritrichomonas foetus. 1985
Isolamento da membrana flagelar de Herpetomonas megaseliae. 1984
A estrutura paraxial de tripanosomatídeos. 1983
Tritrichomonas foetus: characterization of a subcellular fraction containing the costae. 1982
Separação do corpo celular e do flagelo de Herpetomonas megaseliae. 1982
Isolamento e caracterização de uma fração subcelular contendo a costa de Tritrichomonas foetus. 1982
Fluxo oscilante de 22Na em vesículas de membrana sináptica do eletrócito de Electrophorus electricus (L). 1980
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