Robson da Costa

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Farmácia

Departamento:

Departamento de Biotecnologia Farmacêutica

ORCID:

não disponível no Lattes


Formação:

  • King's College London

    | Pós-Doutorado | 2018 - 2019

  • King's College London

    | Pós-Doutorado | 2017 - 2018

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2013 - 2014

  • Universidade Federal de Santa Catarina

    Farmacologia | Doutorado | 2009 - 2013

  • Universidade Federal de Santa Catarina

    Farmacologia | Mestrado | 2007 - 2009

  • Universidade Federal de Santa Catarina

    Farmácia & Bioquímica | Graduação | 2001 - 2006
Laboratórios:
Nuvens de Palavras:
Artigos:

(96.55% artigos com DOI)

Titulo DOI Ano
P2X7 receptor contributes to long-term neuroinflammation and cognitive impairment in sepsis-surviving mice 10.3389/fphar.2023.1179723 2023
PPAR𝛾 PARTIAL-AGONIST PREVENTS THE PACLITAXEL-INDUCED PERIPHERAL NEUROPATHY IN MICE: IMPACT ON NEUROINFLAMMATION 10.1111/bph.16244 2023
Mitotherapy prevents peripheral neuropathy induced by oxaliplatin in mice 10.1016/j.neuropharm.2023.109828 2023
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice 10.1016/j.celrep.2023.112189 2023
Innate immune memory mediates increased susceptibility to Alzheime-s disease-like pathology in sepsis surviving mice 10.1016/j.bbi.2021.04.001 2021
Taxane-induced neurotoxicity: pathophysiology and therapeutic perspectives 10.1111/bph.15086 2020
Spinal blockage of CXCL1 and its receptor CXCR2 inhibits paclitaxel-induced peripheral neuropathy in mice 10.1016/j.neuropharm.2019.04.014 2019
The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice 10.1016/j.ejphar.2019.172408 2019
Pharmacological Treatment of Chemotherapy-Induced Neuropathic Pain: PPARγ Agonists as a Promising Tool 10.3389/fnins.2019.00907 2019
Promiscuous G-protein coupled receptor inhibition of transient receptor potential melastatin 3 ion channels by Gβγ subunits 10.1523/jneurosci.0882-19.2019 2019
Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice 10.1007/s12035-016-0307-3 2018
Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli -Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice 10.1155/2018/4904696 2018
Kinin Receptors Sensitize TRPV4 Channel and Induce Mechanical Hyperalgesia: Relevance to Paclitaxel-Induced Peripheral Neuropathy in Mice 10.1007/s12035-017-0475-9 2017
Antiallodynic effect of β-caryophyllene on paclitaxel-induced peripheral neuropathy in mice 10.1016/j.neuropharm.2017.07.015 2017
Cinnamaldehyde modulates LPS-induced systemic inflammatory response syndrome through TRPA1-dependent and independent mechanisms 10.1016/j.intimp.2016.02.012 2016
Temporal and Regional Expression of Glucose-Dependent Insulinotropic Peptide and Its Receptor in Spinal Cord Injured Rats 10.1089/neu.2015.3877 2016
B2 receptor blockage prevents Aβ-induced cognitive impairment by neuroinflammation inhibition 10.1016/j.bbr.2014.10.040 2015
Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice 10.1038/jid.2015.183 2015
Toxicological Evaluation of Anti-Scrapie Trimethoxychalcones and Oxadiazoles 10.1590/0001-3765201520140712 2015
The antinociceptive effects of the tetracyclic triterpene euphol in inflammatory and neuropathic pain models: The potential role of PKCε 10.1016/j.neuroscience.2015.06.051 2015
The role of keratinocyte-derived chemokine (KC) on hyperalgesia caused by peripheral nerve injury in mice 10.1016/j.neuropharm.2013.10.026 2014
Inflammatory muscle pain is dependent on the activation of kinin B1 and B2 receptors and intracellular kinase pathways 10.1111/j.1476-5381.2012.01830.x 2012
Activation of the alpha-7 nicotinic acetylcholine receptor (α7 nAchR) reverses referred mechanical hyperalgesia induced by colonic inflammation in mice 10.1016/j.neuropharm.2012.06.004 2012
Anti-nociceptive effect of kinin B1 and B2 receptor antagonists on peripheral neuropathy induced by paclitaxel in mice 10.1111/j.1476-5381.2011.01408.x 2011
The role of kinin B1 and B2 receptors in the scratching behaviour induced by proteinase-activated receptor-2 agonists in mice 10.1111/j.1476-5381.2009.00571.x 2010
Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw 10.1016/j.bcp.2008.12.025 2009
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice 10.1038/bjp.2008.172 2008
Evaluation of antimetastatic activity and systemic toxicity of camptothecin-loaded microspheres in mice injected with B16-F10 melanoma cells 2006
Effect of novel selective non-peptide kinin B1 receptor antagonists on mouse pleurisy induced by carrageenan 10.1016/j.peptides.2006.07.007 2006
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice 2019
Promiscuous GPCR Modulation of TRPM3: A Novel Analgesic Pathway? 2019
A role for TRPM3 channel in osteoarthritis pain 2019
(PF78) The Selective TRPV4 Channel Antagonist HC-067047 Attenuates Mechanical Allodynia in Diabetic Mice 2019
(PF97) Supplementation with concentrate fish oil prevents chemotherapy-induced painful neuropathy in mice 2019
(PF11) Promiscuous G-protein Coupled Receptor Modulation of the Transient Receptor Melastatin 3 Ion Channel: A Novel Analgesic Pathway? 2019
(PF12) Systemic and Spinal Blockage of CXCL1 and its Receptor CXCR2 Inhibits Paclitaxel-Induced Peripheral Neuropathy in Mice 2019
Caracterização do impacto da infecção pelo vírus Chikungunya sobre o desenvolvimento de neuropatia diabética em camundongos 2019
Alterações comportamentais induzidas pela infecção com o vírus Chikungunya em camundongos 2019
Caracterização do modelo de psoríase induzida por imiquimode em camundongos 2018
Envolvimento da resposta ao estresse do retículo endoplasmático desencadeada pela sepse 2018
Caracterização das respostas nociceptivas induzidas pelo vírus Chikungunya em camundongos 2018
The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice 2018
Avaliação dos níveis de expressão do canal TRPV4 em um modelo de neuropatia diabética dolorosa 2017
Inflamação da medula espinhal como alvo para o tratamento da neuropatia periférica induzida pelo paclitaxel. 2017
Efeito anti-nociceptivo do antagonista seletivo do canal TRPV4, HC-067047, em camundongos com neuropatia diabética dolorosa 2017
Spinal Cord CXCL1/CXCR2 Signalling Mediates the Development of Paclitaxel-Induced Peripheral Neuropathy in Mice 2016
SINALIZAÇÃO DE CXCL1/CXCR2 NA MEDULA ESPINHAL MEDEIA O DESENVOLVIMENTO DA NEUROPATIA PERIFÉRICA INDUZIDA POR PACLITAXEL EM CAMUNDONGOS 2016
CHRONIC ADMINISTRATION OF FISH OIL IS CAPABLE OF PREVENTING INFLAMMAORY AND NEUROPATHIC PAIN IN MICE 2016
Antagonism of TRPV4 channel reduced depression-like behaviour in mice 2016
Cheek injection of the selective TRPV4 agonist GSK1016790A elicited scratching behavior in mice 2016
Mechanisms Underlying the Scratching Behavior Induced by the Activation of Proteinase-Activated Receptor-4 in Mice 2015
Proteinase Activated Receptor-4 Agonist Elicits TRP-Mediated In Vitro And In Vivo Responses 2015
O PAPEL DO RECEPTOR DE POTENCIAL TRANSITÓRIO VANILÓIDE-4 (TRPV4) NA NEUROPATIA DIABÉTICA DOLOROSA 2015
Role of transient receptor potential vanilloid-4 (TRPV4) channel in diabetic peripheral neurophaty in mice 2015
ESTUDO DO ENVOLVIMENTO DO CANAL TRPV4 NA NEUROPATIA DIABÉTICA EM CAMUNDONGOS 2015
EFEITO DO ANTAGONISTA SELETIVO DO CANAL TRPV4 SOBRE O COMPORTAMENTO DE COÇAR EM CAMUNDONGOS 2015
EFFECT OF THE SELECTIVE TRPV4 CHANNEL ANTAGONIST ON THE SCRATCHING BEHAVIOUR IN MICE 2015
EFEITO DO ANTAGONISTA SELETIVO DO CANAL TRPV4 SOBRE O COMPORTAMENTO DE COÇAR EM CAMUNDONGOS 2015
ANTINOCICEPTIVE EFFECT OF BETA-CARYOPHYLLENE IN PACLITAXEL-INDUCED PERIPHERAL NEUROPATHY 2014
THE KININ B2 RECEPTOR MEDIATES AMYLOID-β-INDUCED NEUROINFLAMMATION: THE PARTICIPATION OF MAPKS SIGNALING 2013
EFEITO DO BETA-CARIOFILENO NA NEUROPATIA PERIFÉRICA INDUZIDA POR PACLITAXEL 2013
Bradykinin sensitizes the transient potential vanilloid 4 (TRPV4) to cause nociception in mice: influence on paclitaxel-induced peripheral neuropathy 2012
ROLE FOR CXCR2 CHEMOKINE RECEPTORS IN INFLAMMATION AND NOCICEPTION IN CYCLOPHOSPHAMIDE-INDUCED CYSTITIS 2012
INHIBITION OF KERATINOCYTE-DERIVED CHEMOKINE (KC) IS MORE EFFICIENT AT PREVENTING THE DEVELOPMENT OF HYPERALGESIA THAN REVERSING ESTABLISHED PAIN HYPERSENSITIVITY AFTER PERIPHERAL NERVE INJURY IN MICE 2012
ROLE FOR CXCR2 CHEMOKINE RECEPTORS IN INFLAMMATION AND 2012
The role of kinin B2 receptor on amyloid-ß? induced neuroinflammation in vivo: Evidence for the modulation of PKC and MAPK pathways 2012
Involvement of transient receptor potential ankirin 1 (TRPA1) in the persistent scratching behavior induced by diphenilciclopropenone (DCP) in mice 2012
Anti-nociceptive effect of kinin B1 and B2 receptor antagonists on peripheral neuropathy induced by paclitaxel in mice 2011
PROTEINASE ACTIVATED RECEPTOR-4 (PAR-4) EXPRESSED IN SKIN MAST CELLS AND PRURICEPTIVE NEURONS MEDIATES ITCH-LIKE BEHAVIOUR IN MICE 2011
Anti-nociceptive effect of kinin B1 and B2 receptor antagonists on peripheral neuropathy induced by paclitaxel in mice 2011
Mechanisms underlyning the scratching behaviour induced by the activation of proteinase activated receptor-4 (PAR-4) in mice 2010
Analisys of the scratching behaviour induced by the proteinase activated receptor- (PAR-4) agonist AYPGKF-NH2 in mice 2009
INVOLVEMENT OF BOTH KININ B2 AND B1 RECEPTORS ON SCRATCHING BEHAVIOUR INDUCED BY ACTIVATORS OF PROTEINASE-ACTIVATED RECEPTOR-2 (PAR-2) IN MICE 2008
Involvement of both kinin B2 and B1 receptors in the scratching behaviour induced by activators of proteinase-activated receptor-2 (PAR-2) in mice 2008
Nicotine ameliorates dextran sulfate sodium (DSS)-induced colitis and inhibits colitis-associated referred hypersensitivity in mice 2008
Mechanisms underlying the overt nociception and mechanical hypernociception induced by platelet-activating factor (PAF) in the rat paw 2008
Scratching behavior in mice elicited by proteinase-activated receptor-2 (PAR-2) activation is mediated by neurogenic inflammation 2007
Anti-allergic effect of selective non-peptide kinin B1 receptor antagonist SSR240612 on mouse ovalbumin-induced pleurisy 2006
Additional evidence on the effects of novel selective non-peptide kinin B1 receptor antagonists in mouse carrageenan-induced pleurisy 2006
Relevance of cell migration for nociceptive and inflammatory responses induced by PAF 2006
Comparação do método imunocromatográfico com a técnica de CCDAE para identificação de benzodiazepínicos em intoxicações agudas. 2005
Efeito do tratamento com antagonistas não-peptídicos para os receptores B1 das cininas sobre a pleurisia induzida pela carragenina. 2005
Effect of sustained-released camptothecin-loaded microspheres on ling metastasis in mice inoculated with B16-F10 melanoma cells 2004
Preparação e caracterização de nanocápsulas contendo pireno a partir do poli-ácido láctico e poli-ácido láctico-co-polietileneglicol. 2004
Preparação e caracterização de nanocápsulas contendo pireno a partir do poli-ácido láctico e poli-ácido láctico-co-polietileneglicol. 2004
Evaluation of therapeutic efficacy of camptothecin-load microspheres using the lung spontaneous metastasis assay 2003
Avaliação da eficácia terapêutica de microesferas de camptotecina em modelo de melanoma murino 2003
Publicações:
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