Helena Lobo Borges
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Ciências Biomédicas
Departamento:
Diretoria Adjunta de Pesquisa/ICB
Formação:
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Universidade Federal do Rio de Janeiro
| Pós-Doutorado | 2005 - 2006
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University Of California, San Diego
| Pós-Doutorado | 2002 - 2005
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Doutorado | 1998 - 2002
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Mestrado | 1996 - 1998
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Universidade Federal do Rio de Janeiro
Biologia | Graduação | 1991 - 1996
Laboratórios:
Nuvens de Palavras:
Artigos:
(92.50% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Therapeutic Potential of Naturally Occurring Small Molecules to Target the Wnt/β-Catenin Signaling Pathway in Colorectal Cancer | 10.3390/cancers14020403 | 2022 |
| p53 Signaling on Microenvironment and Its Contribution to Tissue Chemoresistance | 10.3390/membranes12020202 | 2022 |
| Non-permissive SARS-CoV-2 infection in human neurospheres | 10.1016/j.scr.2021.102436 | 2021 |
| 3-D Endoluminal Ultrasound Biomicroscopic Imaging and Volumetry of Mouse Colon Tumors | 10.1016/j.ultrasmedbio.2021.06.004 | 2021 |
| WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2 | 10.7717/peerj.12262 | 2021 |
| Detection of Mice Colorectal Tumors by Endoluminal Ultrasound Biomicroscopic Images and Quantification of Image Augmented Gray Values Following Injection of VEGFR-2 Targeted Contrast Agent | 10.1016/j.acra.2020.01.013 | 2021 |
| Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating | 10.7717/peerj.12595 | 2021 |
| Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes | 10.1038/s41598-020-57914-x | 2020 |
| Highlights in Resistance Mechanism Pathways for Combination Therapy | 10.3390/cells8091013 | 2019 |
| The Chalcone Lonchocarpin Inhibits Wnt/β-Catenin Signaling and Suppresses Colorectal Cancer Proliferation | 10.3390/cancers11121968 | 2019 |
| Specific cytostatic and cytotoxic effect of dihydrochelerythrine in glioblastoma cells: role of NF-kB/b-catenin and STAT3/IL-6 pathways | 10.2174/1871520618666180412122101 | 2018 |
| Could combinations of new and old drugs enhance tumor cell death? | 10.2217/fon-2018-0339 | 2018 |
| Inhibition of pRB Pathway Differentially Modulates Apoptosis in Esophageal Cancer Cells | 10.1016/j.tranon.2017.06.008 | 2017 |
| Regulation of c-Myc and NBS1 by ionizing radiation in glioblastoma cells | 10.1016/j.onsig.2017.12.001 | 2017 |
| The Complex Link between Apoptosis and Autophagy: a Promising New Role for RB | 10.1590/0001-3765201620160127 | 2016 |
| PRB expression in stomach of neonate canine without establish breed | 10.26694/2448-0002.vl1iss1pp28-31 | 2016 |
| Commitment of human pluripotent stem cells to a neural lineage is induced by the pro-estrogenic flavonoid apigenin | 10.3402/arb.v2.29244 | 2015 |
| Glioblastoma cells inhibit astrocytic p53-expression favoring cancer malignancy | 10.1038/oncsis.2014.36 | 2014 |
| Isoquercitrin Suppresses Colon Cancer Cell Growth in Vitro by Targeting the Wnt/ -Catenin Signaling Pathway | 10.1074/jbc.m114.621599 | 2014 |
| In Vivo Endoluminal Ultrasound Biomicroscopic Imaging in a Mouse Model of Colorectal Cancer | 10.1016/j.acra.2012.07.013 | 2013 |
| Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide | 10.1038/cddis.2013.283 | 2013 |
| Immunohistochemical Analysis of Retinoblastoma and β-Catenin as an Assistant Tool in the Differential Diagnosis between Crohn's Disease and Ulcerative Colitis | 10.1371/journal.pone.0070786 | 2013 |
| Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy | 10.3748/wjg.v19.i44.8056 | 2013 |
| Nuclear Expression of -Catenin Promotes RB Stability and Resistance to TNF-Induced Apoptosis in Colon Cancer Cells | 10.1158/1541-7786.mcr-12-0670 | 2013 |
| Glioblastoma: Therapeutic challenges, what lies ahead | 10.1016/j.bbcan.2012.05.004 | 2012 |
| Implications of aneuploidy for stem cell biology and brain therapeutics | 10.3389/fncel.2012.00036 | 2012 |
| Features of In Vitro Ultrasound Biomicroscopic Imaging and Colonoscopy for Detection of Colon Tumor in Mice | 10.1016/j.ultrasmedbio.2011.09.003 | 2011 |
| Agathisflavone Enhances Retinoic Acid-Induced Neurogenesis and Its Receptors α and β in Pluripotent Stem Cells | 10.1089/scd.2010.0446 | 2011 |
| Glioblastoma cells: A heterogeneous and fatal tumor interacting with the parenchyma | 10.1016/j.lfs.2011.04.022 | 2011 |
| Inhibition of MAPK/ERK, PKC and CaMKII Signaling Blocks Cytolysin-induced Human Glioma Cell Death | 2010 | |
| Peptide gomesin triggers cell death through L-type channel calcium influx, MAPK/ERK, PKC and PI3K signaling and generation of reactive oxygen species Chemico-Biological Interactions | 10.1016/j.cbi.2010.04.012 | 2010 |
| DNA damage-induced cell death: lessons from the central nervous system | 10.1038/cr.2007.110 | 2008 |
| Potentiation of anticancer-drug cytotoxicity by sea anemone pore-forming proteins in human glioblastoma cells | 10.1097/cad.0b013e3282faa704 | 2008 |
| Reduction of apoptosis in Rb-deficient embryos via Abl knockout. | 10.1038/sj.onc.1210157 | 2007 |
| Acetylation of Mouse p53 at Lysine 317 Negatively Regulates p53 Apoptotic Activities after DNA Damage | 10.1128/MCB.00062-06 | 2006 |
| Tumor Promotion by Caspase-Resistant Retinoblastoma Protein | 10.1073/pnas.0503925102 | 2005 |
| Radiation-Induced Apoptosis in Developing Mouse Retina Exhibits Dose-Dependent Requirement for ATM Phosphorylation of p53. | 10.1038/sj.cdd.4401366 | 2004 |
| Signal-Dependent Protection from Apoptosis in Mice Expressing Caspase-Resistant Rb. AUTORES CHAU e BORGES COM IGUAL CONTRIBUIÇAO | 10.1038/ncb853 | 2002 |
| Gamma irradiation leads two waves of apoptosis in distinct cell populations of the newborn rat retina | 1999 | |
| Death in the dish: control of apoptosis within the developing retinal tissue | 1996 |
Eventos:
(5.00% eventos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| In Vivo and Simultaneously Acquired Endoluminal Ultrasound Biomicroscopic and Colonoscopic Images of Inflamed Mouse Colon and Wall Thickness Measurement | 10.1109/IUS46767.2020.9251491 | 2020 |
| GLIOBLASTOMA CELLS INHIBIT ASTROCYTIC P53-EXPRESSION FAVORING CANCER MALIGNANCY. | 2015 | |
| In Vivo Endoluminal Ultrasound Biomicroscopic Imaging of Colon Lesions in Mouse Models of Cancer and Inflammation | 2011 | |
| UTILIZAÇÃO DA BIOMICROSCOPIA ULTRASSONICA ENDOLUMINAL PARA DETECÇÃO DE LESÕES EM CÓLON DE CAMUNDONGOS | 2010 | |
| ROLE OF RETINOBLASTOMA PROTEIN IN THE VIABILITY OF GLIOBLASTOMA CELLS. | 2010 | |
| Análise da expressão e fosforilação da proteína RB em linhagens de glioblastomas. | 2008 | |
| Análise da Expressão e Fosforilação da proteína RB em linhagens de glioblastomas. | 2008 | |
| Estudo da proteína retinoblastoma na geração de instabilidade cromossômica e diferenciação neuronal de células-tronco embrionárias | 2007 | |
| ATM is necessary to induce apoptosis in both cycling cells and post-mitotic neurons of the developing retina after low dose of gamma irradiation. | 2002 | |
| Early and late waves of apoptosis are differentially associated with cell cycle in the developing retina. | 2001 | |
| Low dose gamma irradiation leads to two waves of apoptosis in distinct cell populations of the developing retina. | 2001 | |
| Resgate da apoptose imediata por antioxidantes induzida por irradiação gama na retina em desenvolvimetno | 1999 | |
| Early and late apoptosis induced by gamma irradiation of the development retina ate differentially associated with the cell cycle | 1998 | |
| Duas ondas de apoptose induzidas por irradiação gama na retina imatura são associadas a fases distintas do ciclo celular | 1998 | |
| Early and late apoptosis induced by gamma irradiation of the development retina are differentially associated with the cell cycle | 1998 | |
| Duas ondas de apoptose induzidas por irradiação gama na retina imatura estão associadas a fases distintas do ciclo celular | 1997 | |
| Early and late apoptosis induced by gamma irradiation of the development retina are differentially associated with the cell cycle | 1997 | |
| Apoptose induzida por irradiação gama na retina em desenvolvimento | 1996 | |
| Apoptosis induced by gamma irradiation of the developing retina | 1996 | |
| Apoptosis induced by gamma irradiation of the developing retina | 1996 |