Susana Frases Carvajal
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Programa de Biologia Celular e Parasitária/Biof
Formação:
-
Albert Einstein College of Medicine
| Pós-Doutorado | 2004 - 2009
-
Universidad Miguel Hernández
Microbiologia | Doutorado | 1999 - 2004
-
Universidad de Alicante
Graduação em Ciências Biológicas | Graduação | 1994 - 1998
-
Colegio Agustinos de Alicante
| Ensino Médio (2o grau) | 1989 - 1994
-
Colegio Franciscanas de ALicante
| Ensino Fundamental (1o grau) | 1982 - 1989
Laboratórios:
Nuvens de Palavras:
Artigos:
(96.99% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Hazards Associated with the Combined Application of Fungicides and Poultry Litter in Agricultural Areas | 10.3390/jox14010007 | 2024 |
| Beyond conventional approaches: Enhancing photodynamic therapy for refractory feline sporotrichosis caused by Sporothrix brasiliensis | 10.1016/j.mmcr.2024.100642 | 2024 |
| In vitro activity of the anthelmintic drug niclosamide against Sporothrix spp. strains with distinct genetic and antifungal susceptibility backgrounds | 10.1007/s42770-024-01301-5 | 2024 |
| In vitro antifungal activity of MMV Pathogen Box® compounds, alone or in combination with antifungal drugs, against mucormycosis agents | 10.1016/j.crmicr.2024.100242 | 2024 |
| Revealing the impact of Rapamycin on the Virulence Factors of the Candida haemulonii Complex | 10.1016/j.crmicr.2024.100247 | 2024 |
| Off-label treatments as potential accelerators in the search for the ideal antifungal treatment of cryptococcosis | 10.2217/fmb-2022-0122 | 2023 |
| Phospholipase B Is Critical for Cryptococcus neoformans Survival in the Central Nervous System | 10.1128/mbio.02640-22 | 2023 |
| Mebendazole Inhibits Histoplasma capsulatum In Vitro Growth and Decreases Mitochondrion and Cytoskeleton Protein Levels | 10.3390/jof9030385 | 2023 |
| Interfacing manganese-based carbonaceous nanocomposites with plasma components: insights on protein interaction, structure and opsonization | 10.1080/07391102.2023.2195943 | 2023 |
| Metabolic and morphostructural plasticity of environmental and animal strains of Nannizzia gypsea | 10.1093/mmy/myad044 | 2023 |
| Unveiling the Morphostructural Plasticity of Zoonotic Sporotrichosis Fungal Strains: Possible Implications for Sporothrix brasiliensis Virulence and Pathogenicity | 10.3390/jof9070701 | 2023 |
| Metabolic Plasticity and Virulence-Associated Factors of Sporothrix brasiliensis Strains Related to Familiar Outbreaks of Cat-to-Human Transmitted Sporotrichosis | 10.3390/jof9070724 | 2023 |
| Assessing the In Vitro Potential of Glatiramer Acetate (Copaxone®) as a Chemotherapeutic Candidate for the Treatment of Cryptococcus neoformans Infection | 10.3390/jof9080783 | 2023 |
| Cyclosporine Affects the Main Virulence Factors of Cryptococcus neoformans In Vitro | 10.3390/jof9040487 | 2023 |
| Repurposing drugs for fungal infections: advantages and limitations | 10.2217/fmb-2023-0108 | 2023 |
| New drugs and other strategies for the treatment of fungal infections | 10.2217/fmb-2023-0169 | 2023 |
| Effect of rapamycin on Cryptococcus neoformans : cellular organization, biophysics and virulence factors | 10.2217/fmb-2023-0097 | 2023 |
| In vitro isavuconazole activity against Sporothrix brasiliensis suggests its efficacy in some severe sporotrichosis cases | 10.2217/fmb-2023-0094 | 2023 |
| A Review on Sporotrichosis and the Emergence of Sporothrix brasiliensis as a Pathogen | 10.1007/s40475-023-00297-6 | 2023 |
| Traversing the Cell Wall: The Chitinolytic Activity of Histoplasma capsulatum Extracellular Vesicles Facilitates Their Release | 10.3390/jof9111052 | 2023 |
| Comparative Analysis of Capsular and Secreted Polysaccharides Produced by Rhodotorula mucilaginosa and Cryptococcus neoformans | 10.3390/jof9111124 | 2023 |
| Harris? hawk ( ) as a source of pathogenic human yeasts: a potential risk to human health | 10.2217/fmb-2021-0166 | 2022 |
| Lessons from protozoans: Phosphate sensing and polyphosphate storage in fungi | 10.1371/journal.ppat.1010298 | 2022 |
| New Insights in Dermatophytes: Microsporum spp. and Nannizzia spp. | 10.1007/s40475-022-00252-x | 2022 |
| Extracellular Vesicles Regulate Biofilm Formation and Yeast-to-Hypha Differentiation in Candida albicans | 10.1128/mbio.00301-22 | 2022 |
| Comparative Biophysical and Ultrastructural Analysis of Melanins Produced by Clinical Strains of Different Species From the Trichosporonaceae Family | 10.3389/fmicb.2022.876611 | 2022 |
| 'One Health and Dermatophytes, what is the Link Between Them?' | 10.26717/BJSTR.2022.44.006995 | 2022 |
| A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity | 10.1016/j.bbadis.2022.166475 | 2022 |
| Vaccination with Live or Heat-Killed Aspergillus fumigatus - sglA Conidia Fully Protects Immunocompromised Mice from Invasive Aspergillosis | 10.1128/mbio.02328-22 | 2022 |
| Screening of Pandemic Response Box Library Reveals the High Activity of Olorofim against Pathogenic Sporothrix Species | 10.3390/jof8101004 | 2022 |
| Clinical Challenges of Emerging and Re-Emerging Yeast Infections in the Context of the COVID-19 Pandemic | 10.3390/microorganisms10112223 | 2022 |
| The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection | 10.3390/cells11233896 | 2022 |
| Metabolic and phenotypic plasticity may contribute for the higher virulence of Trichosporon asahii over other Trichosporonaceae members | 10.1111/myc.13562 | 2022 |
| Histoplasma capsulatum Glycans From Distinct Genotypes Share Structural and Serological Similarities to Cryptococcus neoformans Glucuronoxylomannan | 10.3389/fcimb.2020.565571 | 2021 |
| Dexamethasone and Methylprednisolone Promote Cell Proliferation, Capsule Enlargement, and in vivo Dissemination of C. neoformans | 10.3389/ffunb.2021.643537 | 2021 |
| Ultrastructural Study of Cryptococcus neoformans Surface During Budding Events | 10.3389/fmicb.2021.609244 | 2021 |
| Candida glabrata produces a melanin-like pigment that protects against stress conditions encountered during parasitism | 10.2217/fmb-2020-0228 | 2021 |
| Production of Secreted Carbohydrates that Present Immunologic Similarities with the Cryptococcus Glucuronoxylomannan by Members of the Trichosporonaceae Family: A Comparative Study Among Species of Clinical Interest | 10.1007/s11046-021-00558-w | 2021 |
| Probing the screening of the Casimir interaction with optical tweezers | 10.1103/PhysRevResearch.3.033037 | 2021 |
| Candida spp. co-infection in COVID-19 patients with severe pneumonia: Prevalence study and associated risk factors | 10.1016/j.rmed.2021.106619 | 2021 |
| Treatment with Non-invasive respiratory support in severe COVID-19: Clinical effectiveness observational study | 10.29245/2689-999X/2021/2.1173 | 2021 |
| Neumonía por Aspergillus lentulus en una paciente con diagnóstico de neumonía organizada criptogénica en tratamiento con corticoides orales | 10.1016/j.opresp.2021.100144 | 2021 |
| Medicines for Malaria Venture COVID Box: a source for repurposing drugs with antifungal activity against human pathogenic fungi | 10.1590/0074-02760210207 | 2021 |
| Surface, adhesiveness and virulence aspects of Candida haemulonii species complex | 10.1093/mmy/myz139 | 2020 |
| Endocytosis and Exocytosis in Leishmania amazonensis Are Modulated by Bromoenol Lactone | 10.3389/fcimb.2020.00039 | 2020 |
| Effect of cell geometry in the evaluation of erythrocyte viscoelastic properties | 10.1103/physreve.101.062403 | 2020 |
| Membrane Elastic Properties During Neural Precursor Cell Differentiation | 10.3390/cells9061323 | 2020 |
| Hypervirulence and cross-resistance to a clinical antifungal are induced by an environmental fungicide in Cryptococcus gattii | 10.1016/j.scitotenv.2020.140135 | 2020 |
| Systemic mycoses: a potential alert for complications in COVID-19 patients | 10.2217/fmb-2020-0156 | 2020 |
| Trichosporon asahii as cause of nosocomial pneumonia in patient with COVID-19: A triple co-infection | 10.1016/j.arbres.2020.11.007 | 2020 |
| Prevalence of opportunistic invasive aspergillosis in COVID-19 patients with severe pneumonia | 10.1111/myc.13219 | 2020 |
| Cryptococcus neoformans Glucuronoxylomannan and Sterylglucoside Are Required for Host Protection in an Animal Vaccination Model | 10.1128/mbio.02909-18 | 2019 |
| Interaction with Pantoea agglomerans Modulates Growth and Melanization of Sporothrix brasiliensis and Sporothrix schenckii | 10.1007/s11046-019-00350-x | 2019 |
| Rheological properties of cryptococcal polysaccharide change with fiber size, antibody binding and temperature | 10.2217/fmb-2018-0320 | 2019 |
| The mechanical properties of microbial surfaces and biofilms | 10.1016/j.tcsw.2019.100028 | 2019 |
| Genotypic and Phenotypic Diversity of Cryptococcus gattii VGII Clinical Isolates and Its Impact on Virulence | 10.3389/fmicb.2018.00132 | 2018 |
| Lack of chitin synthase genes impacts capsular architecture and cellular physiology in Cryptococcus neoformans | 10.1016/j.tcsw.2018.05.002 | 2018 |
| A Predicted Mannoprotein Participates in Cryptococcus gattii Capsular Structure | 10.1128/msphere.00023-18 | 2018 |
| Trypanosoma cruzi epimastigotes store cholesteryl esters in lipid droplets after cholesterol endocytosis | 10.1016/j.molbiopara.2018.07.004 | 2018 |
| Surface properties, adhesion and biofilm formation on different surfaces by Scedosporium spp. and Lomentospora prolificans | 10.1080/08927014.2018.1503652 | 2018 |
| Phosphorus-rich structures and capsular architecture in Cryptococcus neoformans | 10.2217/fmb-2017-0060 | 2017 |
| The environmental yeast Cryptococcus liquefaciens produces capsular and secreted polysaccharides with similar pathogenic properties to those of C. neoformans | 10.1038/srep46768 | 2017 |
| Atorvastatin as a promising anticryptococcal agent | 10.1016/j.ijantimicag.2017.04.005 | 2017 |
| Biofilm Formation by Pseudallescheria/Scedosporium Species: A Comparative Study | 10.3389/fmicb.2017.01568 | 2017 |
| Characterization of the antifungal functions of a WGA-Fc (IgG2a) fusion protein binding to cell wall chitin oligomers | 10.1038/s41598-017-12540-y | 2017 |
| The hidden pathogenic potential of environmental fungi | 10.2217/fmb-2017-0124 | 2017 |
| Geometrical Distribution of Cryptococcus neoformans Mediates Flower-Like Biofilm Development | 10.3389/fmicb.2017.02534 | 2017 |
| Enhanced virulence of Histoplasma capsulatum through transfer and surface incorporation of glycans from Cryptococcus neoformans during co-infection | 10.1038/srep21765 | 2016 |
| Yeast-derived biosynthesis of silver/silver chloride nanoparticles and their antiproliferative activity against bacteria | 10.1039/c5ra22727e | 2016 |
| Rheological properties of cells measured by optical tweezers | 10.1186/s13628-016-0031-4 | 2016 |
| Biochemical Characterization of Streptomyces sp. I1.2 Secretome Reveals the Presence of Multienzymatic Complexes Containing Cellulases and Accessory Enzymes | 10.1007/s12155-016-9771-x | 2016 |
| Networks of fibers and factors: regulation of capsule formation in Cryptococcus neoformans | 10.12688/f1000research.8854.1 | 2016 |
| Comprehensive analysis of the cellulolytic system reveals its potential for deconstruction of lignocellulosic biomass in a novel Streptomyces sp. | 10.1007/s00253-016-7851-7 | 2016 |
| Green production of microalgae-based silver chloride nanoparticles with antimicrobial activity against pathogenic bacteria | 10.1016/j.enzmictec.2016.10.018 | 2016 |
| Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids | 10.1128/mbio.00647-15 | 2015 |
| The Cryptococcus neoformans capsule: lessons from the use of optical tweezers and other biophysical tools | 10.3389/fmicb.2015.00640 | 2015 |
| Isolation of aerobic cultivable cellulolytic bacteria from different regions of the gastrointestinal tract of giant land snail Achatina fulica | 10.3389/fmicb.2015.00860 | 2015 |
| Probing the Casimir force with optical tweezers | 10.1209/0295-5075/112/44001 | 2015 |
| Cryptococcus neoformans capsular polysaccharides form branched and complex filamentous networks viewed by high-resolution microscopy | 10.1016/j.jsb.2015.11.010 | 2015 |
| Cryptococcus neoformans glucuronoxylomannan fractions of different molecular masses are functionally distinct | 10.2217/fmb.13.163 | 2014 |
| A Role for LHC1 in Higher Order Structure and Complement Binding of the Cryptococcus neoformans Capsule | 10.1371/journal.ppat.1004037 | 2014 |
| The vacuolar-sorting protein Snf7 is required for export of virulence determinants in members of the Cryptococcus neoformans complex. | 10.1038/srep06198 | 2014 |
| Compositional and immunobiological analyses of extracellular vesicles released by Candida albicans | 10.1111/cmi.12374 | 2014 |
| Fluconazole Alters the Polysaccharide Capsule of Cryptococcus gattii and Leads to Distinct Behaviors in Murine Cryptococcosis | 10.1371/journal.pone.0112669 | 2014 |
| Methamphetamine Alters Blood Brain Barrier Protein Expression Facilitating Central Nervous System Infection by Neurotropic Cryptococcus neoformans | 10.1093/infdis/jit117 | 2013 |
| Binding of the wheat germ lectin to Cryptococcus neoformans chitooligomers affects multiple mechanisms required for fungal pathogenesis | 10.1016/j.fgb.2013.04.005 | 2013 |
| Methamphetamine Enhances Cryptococcus neoformans Pulmonary Infection and Dissemination to the Brain | 10.1128/mBio.00400-13 | 2013 |
| Pyomelanin production: a rare phenotype in Acinetobacter baumannii | 10.1099/jmm.0.064089-0 | 2013 |
| Role of the Apt1 protein in polysaccharide secretion by Cryptococcus neoformans | 10.1128/ec.00273-13 | 2013 |
| Using Solid-state NMR to Monitor the Molecular Consequences of Melanization with Different Catecholamine Precursors | 10.1021/bi300325m | 2012 |
| Biosynthesis and functions of a melanoid pigment produced by species of the Sporothrix complex in presence of L-tyrosine | 10.1128/AEM.02414-12 | 2012 |
| Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells | 10.1371/journal.pone.0029561 | 2012 |
| Antibody Binding to Cryptococcus neoformans Impairs Budding by Altering Capsular Mechanical Properties | 10.4049/jimmunol.1202324 | 2012 |
| Agglutination of Histoplasma capsulatum by IgG Monoclonal Antibodies against Hsp60 Impacts Macrophage Effector Functions | 10.1128/IAI.00673-10 | 2011 |
| Evidence for branching in cryptococcal capsular polysaccharides and consequences on its biological activity | 10.1111/j.1365-2958.2010.07511.x | 2011 |
| Effects of microplusin, a copper-chelating antimicrobial peptide, against Cryptococcus neoformans | 10.1111/j.1574-6968.2011.02386.x | 2011 |
| Biophysical Methods for the Study of Microbial Surfaces | 10.3389/fmicb.2011.00207 | 2011 |
| The use of chitosan to damage Cryptococcus neoformans biofilms | 10.1016/j.biomaterials.2009.09.087 | 2010 |
| Melanin-Covered Nanoparticles for Protection of Bone Marrow During Radiation Therapy of Cancer | 10.1016/j.ijrobp.2010.02.020 | 2010 |
| Immunomodulatory Effects of Serotype B Glucuronoxylomannan from Cryptococcus gattii Correlate with Polysaccharide Diameter | 10.1128/IAI.00111-10 | 2010 |
| Galactoxylomannans from Cryptococcus neoformans Varieties neoformans and grubii Are Structurally and Antigenically Variable | 10.1128/EC.00268-09 | 2010 |
| Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo | 10.1111/j.1462-5822.2010.01430.x | 2010 |
| Characterization of Yeast Extracellular Vesicles: Evidence for the Participation of Different Pathways of Cellular Traffic in Vesicle Biogenesis | 10.1371/journal.pone.0011113 | 2010 |
| Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins | 10.1073/pnas.1008843107 | 2010 |
| Biogenesis of extracellular vesicles in yeast: Many questions with few answers | 10.4161/cib.3.6.12756 | 2010 |
| Monoclonal Antibodies to Heat Shock Protein 60 Alter the Pathogenesis of Histoplasma capsulatum | 10.1128/IAI.01443-08 | 2009 |
| The still obscure attributes of cryptococcal glucuronoxylomannan | 10.1080/13693780902788621 | 2009 |
| The capsule of the fungal pathogen Cryptococcus neoformans | 2009 | |
| Growth conditions influence melanization of Brazilian clinical Sporothrix schenckii isolates | 10.1016/j.micinf.2009.03.002 | 2009 |
| Structural and functional properties of the Trichosporon asahii glucuronoxylomannan | 10.1016/j.fgb.2009.03.003 | 2009 |
| The Elastic Properties of the Cryptococcus neoformans Capsule | 10.1016/j.bpj.2009.04.043 | 2009 |
| Lipophilic Dye Staining of Cryptococcus neoformans Extracellular Vesicles and Capsule | 10.1128/EC.00044-09 | 2009 |
| Role for Chitin and Chitooligomers in the Capsular Architecture of Cryptococcus neoformans | 10.1128/EC.00142-09 | 2009 |
| Molecular epidemiology of isolates of the Cryptococcus neoformans species complex from Spain | 2009 | |
| Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules | 10.1073/pnas.0808995106 | 2009 |
| Galactoxylomannan-Mediated Immunological Paralysis Results from Specific B Cell Depletion in the Context of Widespread Immune System Damage | 10.4049/jimmunol.0900449 | 2009 |
| Sec6-dependent sorting of fungal extracellular exosomes and laccase of | 10.1111/j.1365-2958.2008.06588.x | 2009 |
| Vesicle-associated melanization in Cryptococcus neoformans | 10.1099/mic.0.032854-0 | 2009 |
| Cryptococcus neoformans cryoultramicrotomy and vesicle fractionation reveals an intimate association between membrane lipids and glucuronoxylomannan | 10.1016/j.fgb.2009.09.001 | 2009 |
| Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival | 10.1111/j.1462-5822.2008.01186.x | 2008 |
| Growth and Pigment Production on D-Tryptophan Medium by Cryptococcus gattii, Cryptococcus neoformans, and Candida albicans | 10.1128/JCM.01721-07 | 2008 |
| Cryptococcus neoformans Capsular Polysaccharide and Exopolysaccharide Fractions Manifest Physical, Chemical, and Antigenic Differences | 10.1128/EC.00378-07 | 2008 |
| Following Fungal Melanin Biosynthesis with Solid-State NMR: Biopolymer Molecular Structures and Possible Connections to Cell-Wall Polysaccharides | 10.1021/bi702093r | 2008 |
| Vesicular transport in Histoplasma capsulatum : an effective mechanism for trans-cell wall transfer of proteins and lipids in ascomycetes | 10.1111/j.1462-5822.2008.01160.x | 2008 |
| Cryptococcus neoformans Can Utilize the Bacterial Melanin Precursor Homogentisic Acid for Fungal Melanogenesis | 10.1128/AEM.01947-06 | 2007 |
| Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport | 10.1128/EC.00318-06 | 2007 |
| Self-Aggregation of Cryptococcus neoformans Capsular Glucuronoxylomannan Is Dependent on Divalent Cations (Nimrichter, L. and FRASES, S. have contributed equally to this work) | 10.1128/EC.00122-07 | 2007 |
| Cryptococcus neoformans laccase catalyses melanin synthesis from both D- and L-DOPA | 10.1099/mic.0.2007/011049-0 | 2007 |
| Induction by Klebsiella aerogenes of a Melanin-Like Pigment in Cryptococcus neoformans | 10.1128/AEM.72.2.1542-1550.2006 | 2006 |
| First Case of Human Cryptococcosis Due to Cryptococcus neoformans var. gattii in Spain | 10.1128/JCM.43.7.3548-3550.2005 | 2005 |
| First local case of human cryptococcosis in Spain caused by Cryptococcus neoformans var. gattii | 2003 | |
| Detection and Identification of Fungal Pathogens by PCR and by ITS2 and 5.8S Ribosomal DNA Typing in Ocular Infections | 10.1128/JCM.39.8.2873-2879.2001 | 2001 |
| Epidemiological study of cryptococcosis in Spain: first results | 2001 |
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