Fernando Lucas Palhano Soares
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Bioquímica Médica
Departamento:
Programa de Biologia Molecular e Biotecnologia
Formação:
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The Scripps Research Institute
| Pós-Doutorado | 2011 - 2013
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Universidade Federal do Rio de Janeiro
| Pós-Doutorado | 2009 - 2011
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Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 2005 - 2009
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Universidade Federal do Espírito Santo
Biologia Vegetal | Mestrado | 2004 - 2005
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Universidade Federal do Espírito Santo
Aperfeiçoamento Tecnológico | Aperfeiçoamento | 2002 - 2003
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Universidade Federal do Espírito Santo
Farmácia e Bioquímica | Graduação | 1998 - 2003
Laboratórios:
Nuvens de Palavras:
Artigos:
(95.65% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Enhancing anti-amyloidogenic properties and antioxidant effects of Scutellaria baicalensis polyphenols through novel nanoparticle formation | 10.1016/j.ijbiomac.2024.130003 | 2024 |
| Structural and thermodynamic characterization of a highly amyloidogenic dimer of transthyretin involved in a severe cardiomyopathy | 10.1016/j.jbc.2024.107495 | 2024 |
| Transcriptional profile of ribosome-associated quality control components and their associated phenotypes in mammalian cells | 10.1038/s41598-023-50811-z | 2024 |
| How oxidized EGCG remodels α-synuclein fibrils into non-toxic aggregates: insights from computational simulations | 10.1039/d3cp02261g | 2023 |
| A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity | 10.1016/j.bbadis.2022.166475 | 2022 |
| JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species | 10.1007/s12640-022-00559-7 | 2022 |
| Rqc1 and other yeast proteins containing highly positively charged sequences are not targets of the RQC complex | 10.1016/j.jbc.2021.100586 | 2021 |
| Pentameric Thiophene as a Probe to Monitor EGCG?s Remodeling Activity of Mature Amyloid Fibrils: Overcoming Signal Artifacts of Thioflavin T | 10.1021/acsomega.1c00680 | 2021 |
| Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo | 10.1016/j.ymthe.2021.04.035 | 2021 |
| Green Tea Polyphenol Epigallocatechin-Gallate in Amyloid Aggregation and Neurodegenerative Diseases | 10.3389/fnins.2021.718188 | 2021 |
| A systematic structural comparison of all solved small proteins deposited in PDB. The effect of disulfide bonds in protein fold | 10.1016/j.csbj.2021.11.015 | 2021 |
| Viruses with different genome types adopt a similar strategy to pack nucleic acids based on positively charged protein domains | 10.1038/s41598-020-62328-w | 2020 |
| Green Tea Polyphenol Microparticles Based on the Oxidative Coupling of EGCG Inhibit Amyloid Aggregation/Cytotoxicity and Serve as a Platform for Drug Delivery | 10.1021/acsbiomaterials.0c00188 | 2020 |
| Influence of nascent polypeptide positive charges on translation dynamics | 10.1042/BCJ20200303 | 2020 |
| Natural variation of the cardiac transcriptome in humans | 10.1080/15476286.2020.1857508 | 2020 |
| Acetylsalicylic acid and salicylic acid present anticancer properties against melanoma by promoting nitric oxide-dependent endoplasmic reticulum stress and apoptosis | 10.1038/s41598-020-76824-6 | 2020 |
| New Cardiomyokine Reduces Myocardial Ischemia/Reperfusion Injury by PI3K-AKT Pathway Via a Putative KDEL-Receptor Binding | 10.1161/jaha.120.019685 | 2020 |
| Codon stabilization coefficient as a metric to gain insights into mRNA stability and codon bias and their relationships with translation | 10.1093/nar/gkz033 | 2019 |
| Inflammatory profiling of patients with familial amyloid polyneuropathy | 10.1186/s12883-019-1369-4 | 2019 |
| From reporters to endogenous genes: the impact of the first five codons on translation efficiency in Escherichia coli | 10.1080/15476286.2019.1661213 | 2019 |
| Selective and sensitive pull down of amyloid fibrils produced in vitro and in vivo by the use of pentameric-thiophene-coupled resins. | 10.1021/acschemneuro.8b00222 | 2018 |
| Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C | 10.1038/s41598-017-00777-6 | 2017 |
| Cavity filling mutations at the thyroxine-binding site dramatically increase transthyretin stability and prevent its aggregation | 10.1038/srep44709 | 2017 |
| Protein charge distribution in proteomes and its impact on translation | 10.1371/journal.pcbi.1005549 | 2017 |
| An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils. | 10.1021/acschemneuro.7b00017 | 2017 |
| Increased ribosome density associated to positively charged residues is evident in ribosome profiling experiments performed in the absence of translation inhibitors | 10.1080/15476286.2016.1172755 | 2016 |
| A metabolic shift towards pentose phosphate pathway is necessary for amyloid fibril- and phorbol 12-myristate 13-acetate -induced neutrophil extracellular trap (NET) formation | 10.1074/jbc.M115.640094 | 2015 |
| Experimental Evidence for a Revision in the Annotation of Putative Pyridoxamine 5'-Phosphate Oxidases P(N/M)P from Fungi | 10.1371/journal.pone.0136761 | 2015 |
| The Solution Structure and Dynamics of Full-length Human Cerebral Dopamine Neurotrophic Factor and Its Neuroprotective Role Against α-Synuclein Oligomers | 10.1074/jbc.m115.662254 | 2015 |
| Immunoprecipitation of Amyloid Fibrils by the Use of an Antibody that Recognizes a Generic Epitope Common to Amyloid Fibrils | 10.1371/journal.pone.0105433 | 2014 |
| Conformational Changes in Human Hsp70 Induced by High Hydrostatic Pressure Produce Oligomers with ATPase Activity but without Chaperone Activity | 10.1021/bi500004q | 2014 |
| Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis | 10.1038/cddis.2013.325 | 2013 |
| Toward the Molecular Mechanism(s) by Which EGCG Treatment Remodels Mature Amyloid Fibrils | 10.1021/ja3115696 | 2013 |
| Surface adsorption considerations when working with amyloid fibrils in multiwell plates and Eppendorf tubes | 10.1002/pro.2339 | 2013 |
| Amyloid Fibrils Trigger the Release of Neutrophil Extracellular Traps (NETs), Causing Fibril Fragmentation by NET-associated Elastase | 10.1074/jbc.M112.369942 | 2012 |
| Dissecting the Structure, Thermodynamic Stability, and Aggregation Properties of the A25T Transthyretin (A25T-TTR) Variant Involved in Leptomeningeal Amyloidosis: Identifying Protein Partners That Co-Aggregate during A25T-TTR Fibrillogenesis in Cerebrospinal Fluid | 10.1021/bi201365r | 2011 |
| The Anti-Parkinsonian Drug Selegiline Delays the Nucleation Phase of ?-Synuclein Aggregation Leading to the Formation of Nontoxic Species | 10.1016/j.jmb.2010.10.027 | 2011 |
| Identification of archaeal proteins that affect the exosome function in vitro | 10.1186/1471-2091-11-22 | 2010 |
| Biotechnological properties of distillery and laboratory yeasts in response to industrial stresses | 10.1007/s10295-010-0755-0 | 2010 |
| A Fluorescent Mutant of the NM Domain of the Yeast Prion Sup35 Provides Insight into Fibril Formation and Stability | 10.1021/bi9000276 | 2009 |
| Trapping the monomer of a non-amyloidogenic variant of transthyretin: exploring its possible use as a therapeutic strategy against transthyretin amyloidogenic diseases. | 10.1074/jbc.M807100200 | 2009 |
| Changes In Transcription and Protein Profile Induced By Hydrostatic Pressure Treatment In Microorganisms in Micro-organisms | 2008 | |
| Induction of baroresistance by hydrogen peroxide, ethanol and cold-shock in Saccharomyces cerevisiae | 10.1016/j.femsle.2004.02.002 | 2004 |
| Pressure response in the yeast Saccharomyces cerevisiae: from cellular to molecular approaches | 2004 | |
| Inactivation of Colletotrichum gloeosporioides spores by high hydrostatic pressure combined with citral or lemongrass essential oil | 10.1016/j.ijfoodmicro.2004.02.002 | 2004 |
| Role of nitric oxide in the response of cells to heat shock and high hydrostatic pressure | 10.1016/s1567-1356(03)00039-4 | 2003 |
Eventos:
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