Jerson Lima da Silva
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Bioquímica Médica
Departamento:
Gabinete do Diretor do Instituto de Bioquímica Médica
Formação:
-
University of Illinois at Urbana-Champaign
| Pós-Doutorado | 1991 - 1992
-
Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Doutorado | 1983 - 1987
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Universidade Federal do Rio de Janeiro
MEDICINA | Graduação | 1979 - 1984
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University of Illinois - System
| Pós-Doutorado | 0 - 1987
Laboratórios:
Nuvens de Palavras:
Artigos:
(82.61% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| SARS-CoV-2 spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID syndrome in mice | 10.1016/j.celrep.2023.112189 | 2023 |
| Conformational stability of SARS-CoV-2 glycoprotein spike variants | 10.1016/j.isci.2022.105696 | 2023 |
| PRIMA-1 inhibits Y220C p53 amyloid aggregation and synergizes with cisplatin in hepatocellular carcinoma | 10.3389/fmolb.2023.1165132 | 2023 |
| SARS-CoV-2 Spike protein alters microglial purinergic signaling | 10.3389/fimmu.2023.1158460 | 2023 |
| Targeting Biomolecular Condensation and Protein Aggregation against Cancer | 10.1021/acs.chemrev.3c00131 | 2023 |
| Curcumin and melphalan cotreatment induces cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells | 10.1038/s41598-023-40535-5 | 2023 |
| Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation | 10.1016/j.sbi.2022.102346 | 2022 |
| Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice | 10.1016/j.bbr.2021.113680 | 2022 |
| Immunogenicity of SARS-CoV-2 trimetric spike protein associated to Poly(I:C) plus Alum | 10.3389/fimmu.2022.884760 | 2022 |
| Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice | 10.3390/vaccines10081305 | 2022 |
| Protein of a thousand faces: The tumor-suppressive and oncogenic responses of p53 | 10.3389/fmolb.2022.944955 | 2022 |
| Anticancer Therapeutic Strategies Targeting p53 Aggregation | 10.3390/ijms231911023 | 2022 |
| Evolutionary Role of Water-Accessible Cavities in Src Homology 2 (SH2) Domains | 10.1021/acs.jpcb.2c05409 | 2022 |
| The chameleonic behavior of p53 in health and disease: the transition from a client to an aberrant condensate scaffold in cancer | 10.1042/EBC20220064 | 2022 |
| Aminoquinolones and Their Benzoquinone Dimer Hybrids as Modulators of Prion Protein Conversion | 10.3390/molecules27227935 | 2022 |
| Water Leakage Pathway Leads to Internal Hydration of the p53 Core Domain | 10.1021/acs.biochem.2c00320 | 2022 |
| The interplay between a GC-rich oligonucleotide and copper ions on prion protein conformational and phase transitions | 10.1016/j.ijbiomac.2021.01.097 | 2021 |
| COVID-19 and the challenges of chemotherapy: The failure case of hydroxychloroquine in the clinical treatment of SARS-CoV-2 infection | 10.2174/2666796702999210112202907 | 2021 |
| Effects of lycopene from guava ( Psidium guajava L.) derived products on breast cancer cells | 10.1080/14786419.2021.1880402 | 2021 |
| Inactivation of avian influenza viruses by hydrostatic pressure as a potential vaccine development approach | 10.1099/acmi.0.000220 | 2021 |
| Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands | 10.1039/D1SC01739J | 2021 |
| Anomalous structural dynamics of minimally frustrated residues in cardiac troponin C triggers hypertrophic cardiomyopathy | 10.1039/D1SC01886H | 2021 |
| Cryo-EM to visualize the structural organization of viruses | 10.1016/j.coviro.2021.04.011 | 2021 |
| RABBIT PrP IS PARTIALLY RESISTANT TO IN VITRO AGGREGATION INDUCED BY DIFFERENT BIOLOGICAL COFACTORS | 10.3389/fnins.2021.689315 | 2021 |
| Process intensification for the production of yellow fever virus-like particles (VLPs) as potential recombinant vaccine antigen | 10.1002/bit.27864 | 2021 |
| Pro-Oxidant Effect of Resveratrol on Human Breast Cancer MCF-7 Cells is Associated with CK2 Inhibition | 10.1080/01635581.2021.1977834 | 2021 |
| Polyclonal F(ab?)2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency | 10.1016/j.isci.2021.103315 | 2021 |
| Yellow fever vaccine protects mice against Zika virus infection | 10.1371/journal.pntd.0009907 | 2021 |
| Green Tea (Camellia sinensis) Extract Induces p53-Mediated Cytotoxicity and Inhibits Migration of Breast Cancer Cells | 10.3390/foods10123154 | 2021 |
| Oncogenic gain of function in glioblastoma is linked to mutant p53 amyloid oligomers | 10.1016/j.isci.2020.100820 | 2020 |
| Liquid-liquid phase separation and fibrillation of the prion protein modulated by a high-affinity DNA aptamer | 10.1096/fj.201901897r | 2020 |
| Resveratrol Modifies Lipid Composition of Two Cancer Cell Lines | 10.1155/2020/5393041 | 2020 |
| Anticancer Potential of Resveratrol, β-Lapachone and Their Analogues | 10.3390/molecules25040893 | 2020 |
| The Status of p53 Oligomeric and Aggregation States in Cancer | 10.3390/biom10040548 | 2020 |
| Recent Synthetic Approaches towards Small Molecule Reactivators of p53 | 10.3390/biom10040635 | 2020 |
| Agathisflavone, a Biflavonoid from Anacardium occidentale L., Inhibits Influenza Virus Neuraminidase | 10.2174/1568026620666191219150738 | 2020 |
| Microscopy analysis of Zika virus morphogenesis in mammalian cells | 10.1038/s41598-020-65409-y | 2020 |
| Resveratrol, Curcumin and Piperine Alter Human Glyoxalase 1 in MCF-7 Breast Cancer Cells | 10.3390/ijms21155244 | 2020 |
| Bioactive Compounds and Metabolites from Grapes and Red Wine in Breast Cancer Chemoprevention and Therapy | 10.3390/molecules25153531 | 2020 |
| Second-Generation RT-QuIC Assay for the Diagnosis of Creutzfeldt-Jakob Disease Patients in Brazil | 10.3389/fbioe.2020.00929 | 2020 |
| Exploring the polymorphism, conformational dynamics and function of amyloidogenic peptides and proteins by temperature and pressure modulation | 10.1016/j.bpc.2020.106506 | 2020 |
| p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells | 10.1074/jbc.RA118.004671 | 2019 |
| High pressure studies on the misfolding and aggregation of p53 in cancer and of α-synuclein in Parkinson?s disease | 10.1080/08957959.2019.1576173 | 2019 |
| Modulation of p53 and prion protein aggregation by RNA | 10.1016/j.bbapap.2019.02.006 | 2019 |
| Loss of the p53 transactivation domain results in high amyloid aggregation of the -40p53 isoform in endometrial carcinoma cells | 10.1074/jbc.RA119.007566 | 2019 |
| RNA modulates aggregation of the recombinant mammalian prion protein by direct interaction | 10.1038/s41598-019-48883-x | 2019 |
| Increase in fatty acids and flotillins upon resveratrol treatment of human breast cancer cells | 10.1038/s41598-019-50416-5 | 2019 |
| Liquid-liquid phase transitions and amyloid aggregation in proteins related to cancer and neurodegenerative diseases | 2019 | |
| Alpha-synuclein stepwise aggregation reveals features of an early onset mutation in Parkinson?s disease | 10.1038/s42003-019-0598-9 | 2019 |
| The intrinsically disordered carboxy-terminus of troponin-T binds to troponin-C to modulate myocardial force generation | 10.1074/jbc.RA119.011177 | 2019 |
| Biophysical characterization of p53 core domain aggregates | 10.1042/bcj20190778 | 2019 |
| Resveratrol prevents p53 aggregation in vitro and in breast cancer cells | 10.18632/oncotarget.25631 | 2018 |
| Aggregation-primed molten globule conformers of the p53 core domain provide potential tools for studying p53C aggregation in cancer | 10.1074/jbc.ra118.003285 | 2018 |
| Allosteric transmission along a loosely structured backbone allows a cardiac Troponin C mutant to function with only one Ca2+ ion | 10.1074/jbc.M116.765362 | 2017 |
| The push-and-pull hypothesis in protein unfolding, misfolding and aggregation | 10.1016/j.bpc.2017.03.007 | 2017 |
| Stability of different influenza subtypes: How can high hydrostatic pressure be a useful tool for vaccine development? | 10.1016/j.bpc.2017.04.002 | 2017 |
| Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C | 10.1038/s41598-017-00777-6 | 2017 |
| Distinct modulatory role of RNA in the aggregation of the tumor suppressor protein p53 core domain | 10.1074/jbc.m116.762096 | 2017 |
| On the entry of an emerging arbovirus into host cells: Mayaro virus takes the highway to the cytoplasm through fusion with early endosomes and caveolae-derived vesicles | 10.7717/peerj.3245 | 2017 |
| Cancer Chemoprevention by Resveratrol: The p53 Tumor Suppressor Protein as a Promising Molecular Target | 10.3390/molecules22061014 | 2017 |
| Targeting the Prion-like Aggregation of Mutant p53 to Combat Cancer | 10.1021/acs.accounts.7b00473 | 2017 |
| A biophysical characterization of the interaction of a hepatitis c virus membranotropic peptide with micelles | 10.1016/j.bbapap.2016.01.003 | 2016 |
| Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease? | 10.1101/cshperspect.a023614 | 2016 |
| Aggregation tendencies in the p53 family are modulated by backbone hydrogen bonds | 10.1038/srep32535 | 2016 |
| Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein | 10.7717/peerj.2670 | 2016 |
| Structural basis for the dissociation of α-synuclein fibrils triggered by pressure perturbation of the hydrophobic core | 10.1038/srep37990 | 2016 |
| The -Jekyll and Hyde- Actions of Nucleic Acids on the Prion-like Aggregation of Proteins | 10.1074/jbc.r116.733428 | 2016 |
| Regulation of Amyloid β Oligomer Binding to Neurons and Neurotoxicity by the Prion Protein-mGluR5 Complex | 10.1074/jbc.m116.738286 | 2016 |
| Prion protein-coated magnetic beads: Synthesis, characterization and development of a new ligands screening method | 10.1016/j.chroma.2014.12.014 | 2015 |
| Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer | 10.3389/fonc.2015.00097 | 2015 |
| A hypothesis to reconcile the physical and chemical unfolding of proteins | 10.1073/pnas.1500352112 | 2015 |
| The increasing velocity of S&T in the State of Rio de Janeiro | 2015 | |
| Intranasal Immunization with Pressure Inactivated Avian Influenza Elicits Cellular and Humoral Responses in Mice | 10.1371/journal.pone.0128785 | 2015 |
| Backbone resonance assignments of the human p73 DNA binding domain | 10.1007/s12104-015-9635-x | 2015 |
| The aggregation of mutant p53 produces prion-like properties in cancer | 10.4161/pri.27776 | 2014 |
| Inhibition of Mayaro virus infection by bovine lactoferrin | 10.1016/j.virol.2014.01.022 | 2014 |
| Heparin binding confers prion stability and impairs its aggregation | 10.1096/fj.13-246777 | 2014 |
| Prion-like aggregation of mutant p53 in cancer | 10.1016/j.tibs.2014.04.001 | 2014 |
| Pathological implications of nucleic acid interactions with proteins associated with neurodegenerative diseases | 10.1007/s12551-013-0132-0 | 2014 |
| Biophysical and morphological studies on the dual interaction of non-octarepeat prion protein peptides with copper and nucleic acids | 10.1007/s00775-014-1115-8 | 2014 |
| High-Pressure Chemical Biology and Biotechnology | 10.1021/cr400204z | 2014 |
| Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycle | 10.1016/j.bbapap.2014.12.008 | 2014 |
| Insights into the Intramolecular Coupling between the N- and C-Domains of Troponin C Derived from High-Pressure, Fluorescence, Nuclear Magnetic Resonance, and Small-Angle X-ray Scattering Studies | 10.1021/bi301139d | 2013 |
| Expanding the Prion Concept to Cancer Biology: Dominant-Negative Effect of Aggregates of Mutant p53 Tumor Suppressor | 10.1042/bsr20130065 | 2013 |
| Intramolecular Dynamics within the N-Cap-SH3-SH2 Regulatory Unit of the c-Abl Tyrosine Kinase Reveal Targeting to the Cellular Membrane | 10.1074/jbc.m113.500926 | 2013 |
| Pressure-temperature folding landscape in proteins involved in neurodegenerative diseases and cancer | 10.1016/j.bpc.2013.06.002 | 2013 |
| Fine Modulation of the Respiratory Syncytial Virus M2-1 Protein Quaternary Structure by Reversible Zinc Removal from its Cys3-His1 Motif. | 10.1021/bi401029q | 2013 |
| Full Inactivation of Human Influenza Virus by High Hydrostatic Pressure Preserves Virus Structure and Membrane Fusion While Conferring Protection to Mice against Infection | 10.1371/journal.pone.0080785 | 2013 |
| The role of RNA in mammalian prion protein conversion | 10.1002/wrna.118 | 2012 |
| Non-Specific Prion Protein?Nucleic Acid Interactions Lead to Different Aggregates and Cytotoxic Species | 10.1021/bi300440e | 2012 |
| Transient Transfection of a Wild-Type p53 Gene Triggers Resveratrol-Induced Apoptosis in Cancer Cells | 10.1371/journal.pone.0048746 | 2012 |
| Mice Vaccination with High Hydrostatic Pressure-Inactivated H3N8 Virus Protects Against Experimental Avian Flu | 10.1016/j.provac.2012.04.014 | 2012 |
| Resveratrol chemosensitizes breast cancer cells to melphalan by cell cycle arrest | 10.1002/jcb.24134 | 2012 |
| Mutant p53 Aggregates into Prion-like Amyloid Oligomers and Fibrils: IMPLICATIONS FOR CANCER | 10.1074/jbc.M112.340638 | 2012 |
| The Structural Dynamics of the Flavivirus Fusion Peptide?Membrane Interaction | 10.1371/journal.pone.0047596 | 2012 |
| Moniliophthora perniciosa Necrosis- and Ethylene-Inducing Protein 2 (MpNep2) as a Metastable Dimer in Solution: Structural and Functional Implications | 10.1371/journal.pone.0045620 | 2012 |
| The Anti-Parkinsonian Drug Selegiline Delays the Nucleation Phase of ?-Synuclein Aggregation Leading to the Formation of Nontoxic Species | 10.1016/j.jmb.2010.10.027 | 2011 |
| Co-localization of mutant p53 and amyloid-like protein aggregates in breast tumors | 10.1016/j.biocel.2010.10.017 | 2011 |
| Heparin Binding by Murine Recombinant Prion Protein Leads to Transient Aggregation and Formation of RNA-Resistant Species | 10.1021/ja106725p | 2011 |
| Measuring the Strength of Interaction between the Ebola Fusion Peptide and Lipid Rafts: Implications for Membrane Fusion and Virus Infection | 10.1371/journal.pone.0015756 | 2011 |
| Envelope Lipid-packing as a Critical Factor for the Biological Activity and Stability of Alphavirus Particles Isolated from Mammalian and Mosquito Cells | 10.1074/jbc.M110.198002 | 2011 |
| Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion | 10.1016/j.ymeth.2010.12.002 | 2011 |
| Functional and Pathological Roles of Prion-Nucleic Acid Interactions | 10.2741/3611 | 2010 |
| Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins | 10.1021/ar900179t | 2010 |
| The p53 core domain is a molten globule at low pH: Functional implications of a partially unfolded structure | 10.1074/jbc.M109.075861 | 2010 |
| Positive response to imatinib mesylate therapy for childhood chronic myeloid leukemia | 10.1590/S0100-879X2010007500026 | 2010 |
| Synthesis and anti-prion activity evaluation of aminoquinoline analogues | 10.1016/j.ejmech.2010.07.054 | 2010 |
| CONFORMATIONAL SELECTION, DYNAMIC RESTRICTION AND HYDROPHOBIC EFFECT COUPLED TO THE STABILIZATION OF THE BIR3 DOMAIN OF HUMAN X-LINKED INHIBITOR OF APOPTOSIS PROTEIN BY THE TETRAPEPTIDE AVPI | 10.1016/j.bpc.2010.08.005 | 2010 |
| Resveratrol: Composto bioativo presente em alimentos e seus efeitos em células tumorais de mama | 2010 | |
| Hydration, cavities and volume in protein folding, aggregation and amyloid assembly | 10.1088/1478-3975/6/1/015002 | 2009 |
| Response to Radulescu and Brenig: Infectious nucleic acids in prion disease: halfway through | 10.1016/j.tibs.2008.10.001 | 2009 |
| Enhanced prion protein stability coupled to DNA recognition and milieu acidification | 10.1016/j.bpc.2008.12.011 | 2009 |
| Cognate DNA Stabilizes the Tumor Suppressor p53 and Prevents Misfolding and Aggregation | 10.1021/bi9003028 | 2009 |
| Effects of hydrostatic pressure on the stability and thermostability of poliovirus: a new method for vaccine preservation | 10.1016/j.vaccine.2009.06.099 | 2009 |
| Reciprocal remodeling upon binding of the Prion Protein to its signaling partner hop/STI1 | 10.1096/fj.09-138974 | 2009 |
| Science and technology to combat dengue virus | 10.1590/S0001-37652009000400001 | 2009 |
| Intriguing nucleic-acid-binding features of mammalian prion protein | 10.1016/j.tibs.2007.11.003 | 2008 |
| The Proapoptotic Protein Smac/DIABLO Dimer Has the Highest Stability As Measured by Pressure and Urea Denaturation | 10.1021/bi702248n | 2008 |
| Different urea stoichiometries betweeen the dissociation and denaturation of tobacco mosaic virus as probed by hydrostatic pressure | 10.1016/j.bpc.2008.02.010 | 2008 |
| Pressure-inactivated yellow fever 17DD virus: Implications for vaccine development | 10.1016/j.jviromet.2008.03.002 | 2008 |
| Volume and Free Energy of Folding for Troponin C C-Domain: Linkage to Ion Binding and N-Domain Interaction | 10.1021/bi702058t | 2008 |
| Prion protein complexed to N2a cellular RNAs through its N-terminal domain forms aggregates and is toxic to murine neuroblastoma cells | 10.1074/jbc.M802102200 | 2008 |
| Conformational changes in bovine lactoferrin induced by slow or fast temperature increases | 10.1515/BC.2008.116_bchm.just-accepted | 2008 |
| Free-Energy Linkage between Folding and Calcium Binding in EF-Hand Proteins | 10.1529/biophysj.108.135715 | 2008 |
| The peculiar interaction between mammalian prion protein and RNA | 10.4161/pri.2.2.6988 | 2008 |
| VP4 protein from human rhinovirus 14 is released by pressure and locked in the capsid by the antiviral compound WIN | 10.1016/j.jmb.2006.11.033 | 2007 |
| Dopamine affects the stability, hydration and packing of protofibrils and fibrils of wild-type and variants of a-synuclein | 10.1021/bi061871+ | 2007 |
| Structure of the Ebola Fusion Peptide in a Membrane-mimetic Environment and the Interaction with Lipid Rafts. | 10.1074/jbc.M611864200 | 2007 |
| The fusogenic state of Mayaro virus induced by low pH and by hydrostatic pressure | 10.1385/CBB:44:3:325 | 2006 |
| Protein Folding and Aggregation: Two sides of the same coin in the condensation of proteins revealed by pressure studies | 10.1016/j.bbapap.2005.11.012 | 2006 |
| Ca2+ and Mg2+ binding to weak sites of TnC C-domain induces exposure of a large hydrophobic surface that leads to loss of TnC from the thin filament | 10.1016/j.biocel.2005.08.009 | 2006 |
| Dissecting the role of protein-protein and protein-nucleic acid interactions on MS2 bacteriophage stability | 10.1111/j.1742-4658.2006.05167.x | 2006 |
| FT-IR spectroscopy provides a fingerprint for the tetramer and the amyloid fibril of transthyretin | 10.1529/biophysj.106.085928 | 2006 |
| Tetramerization of the LexA repressor in solution: Implications for gene regulation of the E. Coli SOS system at acidic pH | 10.1016/j.jmb.2006.03.069 | 2006 |
| Structural insights into the interaction between prion protein and nucleic acid | 10.1021/bi060532d | 2006 |
| Structure of a membrane-binding domain from a non-enveloped animal virus: Insights into the mechanism of membrane permeability and cell entry | 10.1074/jbc.M604689200 | 2006 |
| The hypothesis of the catalytic action of nucleic acids on the conversion of prion protein | 10.2174/0929866053587138 | 2005 |
| Controlling beta amyloid oligomerization by the use of naphtalene sulfonates: trapping low molecular weight oligomeric species | 10.1074/jbc.M501651200 | 2005 |
| Volume and energy folding landscape of prion protein revealed by pressure | 10.1590/S0100-879X2005000800006 | 2005 |
| The amino-terminal PrP domain is crucial to modulate prion misfolding and aggregation | 10.1529/biophysj.105.067603 | 2005 |
| Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology | 10.1590/S0100-879X2005000800001 | 2005 |
| New Insights into the Mechanisms of Protein Misfolding and Aggregation in Amyloidogenic Diseases derived from Pressure Studies | 10.1021/bi048864a | 2004 |
| Mutations in the hydrophobic core and in the protein-RNA interface affect the packing and stability of icosahedral viruses | 10.1046/j.1432-1033.2003.03911.x | 2004 |
| High Pressure Applications in Medicine and Pharmacology | 10.1088/0953-8984/16/14/002 | 2004 |
| Pressure-inactivated FMDV: a potential vaccine | 10.1016/j.vaccine.2003.10.034 | 2004 |
| Modulation of prion protein oligomerization, aggregation, and beta-sheet conversion by 4,4'-dianilino-1,1'-binaphthyl-5,5'-sulfonate (bis-ANS) | 10.1074/jbc.M312262200 | 2004 |
| Hydration and packing effects on prion folding and beta-sheet conversion: High-pressure spectroscopy and pressure perturbation calorimetry studies | 10.1074/jbc.M404295200 | 2004 |
| Reversible aggregation plays a crucial role on the folding landscape of p53 core domain | 10.1529/biophysj.104.044685 | 2004 |
| Positive contribution of hydration on DNA binding by E2c protein from papillomavirus | 10.1074/jbc.M407696200 | 2004 |
| Virus Stability and Protein-Nucleic Acid Interaction as Studied by High-Pressure Effects on Nodaviruses | 10.1170/T530 | 2004 |
| Pressure-induced fusogenic conformation of vesicular stomatitis virus glycoprotein | 10.1021/bi027207k | 2003 |
| Structural Studies of MS2 Bacteriophage Virus Particle Disassembly by Nuclear Magnetic Resonance Relaxation Measurements | 10.1016/S0006-3495(03)75117-0 | 2003 |
| Inactivation of classical swine fever virus: Association of hydrostatic pressure and ultraviolet irradiation | 10.1016/S0166-0934(02)00289-6 | 2003 |
| Hydration and packing are crucial to amyloidogenesis as revealed by pressure studies on transthyretin variants that either protect or worsen amyloid disease | 10.1016/S0022-2836(03)00368-1 | 2003 |
| Role of hydration in the closed-to-open transition involved in Ca2+-binding by Troponin C | 10.1021/bi027102h | 2003 |
| Dissociation of amyloid fibrils of a-synuclein and transthyretin by pressure reveals their reversible nature and the formation of water-excluded cavities. | 10.1073/pnas.1734009100 | 2003 |
| Fibrillar aggregates of tumor suppressor p53 core domain. | 10.1021/bi034218k | 2003 |
| Conversion of wild-type p53 core domain into a conformation that mimics a hot-spot mutant. | 10.1016/j.jmb.2003.08.026 | 2003 |
| Pressure Induces Folding Intermediates that are Crucial for Protein-DNA Recognition and Virus Assembly | 10.1016/S0167-4838(01)00348-X | 2002 |
| Hydrostatic pressure induces the formation of fusion-active states of enveloped viruses | 10.1074/jbc.M106096200 | 2002 |
| Protein-RNA interactions and virus stability as probed by the dynamics of Tryptophan side chains | 10.1074/jbc.M209174200 | 2002 |
| Pressure Provides New Insights into Protein Folding, Dynamics and Structure | 10.1016/S0968-0004(01)01949-1 | 2001 |
| Effects of Hydrostatic Pressure on the Leptospira interrogans : High Immunogenicity of the Pressure- Inactivated Serovar hardjo | 10.1016/S0264-410X(00)00361-3 | 2001 |
| Local Heterogeneity in the Pressure Denaturation of the Coiled-Coil Tropomyosin because of Subdomain Folding Units | 10.1021/bi0020978 | 2001 |
| The Metastable State of Nucleocapsids of Enveloped Viruses as Probed by High Hydrostatic Pressure | 10.1074/jbc.M010037200 | 2001 |
| Pressure-induced formation of inactive triple-shelled rotavirus particles | 10.1006/jmbi.2001.4512 | 2001 |
| Osmolytes protect mitochondrial FoF1-ATPase complex against pressure inactivation | 10.1016/S0167-4838(01)00137-6 | 2001 |
| DNA Converts Cellular Prion Protein into the Beta-Sheet Conformation and Inhibits Prion Peptide Aggregation | 10.1074/jbc.M106707200 | 2001 |
| Protein folding, misfolding and amyloidogenesis as studied by high pressure | 2001 | |
| Folding and stability studies of wild type (WT) and mutant transthyretin using pressure-induced denaturation: Implications for aggregation | 2001 | |
| LexA Repressor Forms Stable Dimers in Solution: The Role of Specific DNA in Tightening Protein-Protein Interactions. | 10.1074/jbc.275.7.4708 | 2000 |
| Virus Maturation Targets the Capsid to Concerted Disassembly and Unfolding. | 10.1074/jbc.M910145199 | 2000 |
| Effects of naturally occuring polyols and urea on the mitochondrial FoF1ATPase. | 2000 | |
| The Pre-Aggregated State of an Amyloidogenic Protein: Hydrostatic Pressure Converts Native Transthyretin into the Amyloidogenic State. | 10.1073/pnas.97.12.6445 | 2000 |
| Carbohydrates protect mitochondrial F0F1-ATPase complex against thermal inactivation | 2000 | |
| Virus inactivation by anilinonaphtalene sulfonate compounds and comparison with other ligands | 10.1006/bbrc.2000.3402 | 2000 |
| DNA tightens the dimeric DNA binding domain of human papillomavirus E2 protein without changes in volume | 10.1073/pnas.250352197 | 2000 |
| Low Temperature And Pressure Stability Of Picornaviruses: Implication For Virus Uncoating. | 10.1016/S0006-3495(99)77290-5 | 1999 |
| Protein Folding In The Absence Of Chemical Denaturants. Reversible Pressure Denaturation Of The Non-Covalent Complex Formed By The Association Of Two Protein Fragments. | 1999 | |
| Cavity Defects In The Procapsid Of Bacteriophage P22 And The Mechanism Of Capsid Maturation | 1999 | |
| Hydrostatic Pressure Rescues Native Protein From Aggregates. | 10.1002/(SICI)1097-0290(19990605)63:5<552::AID-BIT5>3.0.CO;2-8 | 1999 |
| Effects Of High Pressure And Temperature On The Wildtype And F29w Mutant Forms Of The N-Domain Of Avian Troponin C. | 1999 | |
| Folding Of A Pressure Denatured Model Protein | 10.1073/pnas.96.14.7888 | 1999 |
| Hydrostatic pressure as a tool to study virus assembly: Inactivated vaccines and antiviral drugs. | 1999 | |
| Structure and stability of wildtype and F29W mutant forms of the N-domain of avian troponin C subjected to high pressures. | 1999 | |
| Pressure Effects On The Interaction Between Natural Inhibitor Protein And Mitochondrial F1-Atpase | 1998 | |
| Characterization Of A Partially Folded Monomer Of The Dna-Binding Domain Of Human Papillomavirus E2 Protein Obtained At High Pressure. | 1998 | |
| International symposium on protein condensation. | 1998 | |
| Different Partially Folded States Of The Capsid Protein Of Cowpea Severe Mosaic Virus In The Disassembly Pathway | 10.1006/jmbi.1997.1299 | 1997 |
| A Contribution Of The Mitochondrial Adenosinetriphosphate Inhibitor Protein To The Thermal Stability Of The Fof1-Atpase | 1997 | |
| Formation Of A Denatured Dimer Limits The Stability Of Arc Repressor | 1997 | |
| The Use Of Hydrostatic Pressure As A Tool To Study Viruses And Other Macromolecular Assemblages | 10.1016/S0959-440X(96)80071-6 | 1996 |
| Concentration Dependence Of The Subunit Association Of Oligomers And Viruses And The Modification Of The Latter By Urea Binding | 1996 | |
| Pressure And Cold Denaturation Of Proteins And Viruses | 1996 | |
| Migration Of Vesicular Stomatitis Virus Glycoprotein To The Nucleus Of Infected Cells | 1996 | |
| Mimicry Of The Calcium-Induced Conformational State Of Troponin C By Low Temperature Under Pressure | 10.1073/pnas.93.20.10642 | 1996 |
| The Role Of Entropic Interactions In Viral Capsids: Single-Amino-Acid Substitutions In P22 Bacteriophage Coat Protein Resulting In Loss Of Capsid Stability. | 1995 | |
| Inactivation Of Simian Immunodeficiency Viruses By Hydrostatic Pressure. | 10.1073/pnas.92.15.6935 | 1995 |
| Single-Amino Acid Substitutions In P22 Baceriophage Coat Protein Result In Loss Of Pressure Stability Of The Shells. | 1995 | |
| Cold Denaturation Of An Icosahedral Virus. The Role Of Entropy For Virus Assembly. | 10.1021/bi00008a034 | 1995 |
| Low Temperatures Drives The Conformation Of F29w/N-Domain Troponin C Mutant Towards The Calcium -Bound Form | 1995 | |
| Protein-Rna Interactions In Cowpea Mosaic Virus Studied By Time-Resolved Fluorescence. | 1995 | |
| Intermediates Of Assembly In The Deterministic Dissociation Of Gastropod Hemocyanin By Hydrostatic Pressure. | 1994 | |
| Pressure Denaturation Of P22 Coat Protein Monomers And Its Entropic Stabilization In The Icosahedral Shells. | 1994 | |
| Arc Repressor Will Not Denature In The Absence Of Water. | 10.1006/jmbi.1994.1433 | 1994 |
| Differences In Pressure Stability Of The Three Capsid Components Of Cowpea Mosaic Virus: Implications For Virus Assembly And Disassembly. | 10.1021/bi00193a022 | 1994 |
| Cold Denaturation Of Arc Repressor-Operator Complex: The Role Of Entropy On Protein-Dna Recognition. | 10.1073/pnas.91.17.8244 | 1994 |
| High Pressure Nmr Study Of The Dissociation Of Arc Repressor. | 10.1021/bi00193a020 | 1994 |
| Cytosolic Free Calcium Elevation In Trypanosoma Cruzi Precedes Calcium Mobilization In Myoblasts During Invasion. | 10.1084/jem.180.4.1535 | 1994 |
| Pressure Stability Of Proteins | 10.1146/annurev.physchem.44.1.89 | 1993 |
| Energy Coupling Between Dna Binding And Subunit Association Is Crucial For The Specificity Of A Dna-Protein Interaction | 1993 | |
| Molten Globule Conformation Of Arc Repressor Monomers Determined By High Pressure (1h) Nmr Spectroscopy. | 10.1073/pnas.90.5.1776 | 1993 |
| Pressure Dissociation Of Rna Bacteriophage: The Individuality Of Virus Particles. | 10.1006/jmbi.1993.1347 | 1993 |
| The Drifted And Molten-Globule State Of Proteins Dissociated By Pressure. Braz. J. Med. Biol. Res. 26, 335-440. | 1993 | |
| Effects Of Pressure On Multimeric Proteins And Viruses | 1993 | |
| Pressure studies on protein-DNA interactions. | 1993 | |
| Dissociation Of A Native Dimer To A Molten Globule Monomer. Effects Of Pressure And Dilution On The Association Equilibrium Of Arc Repressor. | 10.1016/0022-2836(92)90669-B | 1992 |
| Effects Of Hydrostatic Pressure On A Membrane-Enveloped Virus: High Immunogenicity Of The Pressue-Inactivated Virus. | 1992 | |
| Pressure And Low Temperature Effects On The Fluorescence Emission Spectra And Lifetime Of The Photosyhthetic Components Of Cyanobacteria. | 1992 | |
| Reassembly Of A Large Multisubunit Protein Promoted By Nonprotein Factors. Effects Of Calcium And Glycerol On The Association Of Extracellular Hemoglobin. | 1991 | |
| Effects Of Hydrostatic Pressure On Rotavirus | 1990 | |
| Anomalous Pressure-Dissociation Of Large Protein Aggregates. Lack Of Concentration Dependence And Irreversibility At Extreme Degrees Of Dissociation Of Extracellular Hemoglobin | 1989 | |
| Pressure-Induced Dissociation Of Brome Mosaic Virus. | 10.1016/0022-2836(88)90385-3 | 1988 |
| Effect Of Hydrostatic Pressure On The Mitochondrial Atp Synthase. | 10.1021/bi00418a010 | 1988 |
| Slab Gel Electrophoresis Of Oligomeric Proteins Under Pressure. I. Description Of The System And Resolution Of The Pressure Dissociation Of A Dimer. | 1987 | |
| Pressure Dissociation And Conformational Drift Of The Beta Dimer Of Tryptophan Synthase. | 10.1021/bi00367a065 | 1986 |
| Increased Proteolytic Susceptibility Of Conformationally Drifted Lactate Dehydrogenase. | 1986 | |
| Monomer-Dimer Association Constant Of Solubilized Sarcoplasmic Reticulum Atpase. | 1985 | |
| Self-Association And Modification Of Calcium Binding In Solubilized Sarcoplasmic Reticulum Atpase. | 1983 | |
| Different Degrees of Cooperativity of the Ca2+ - Induced Changes in Fluorescence Intensity of Solubilized Sarcoplasmatic Reticulum ATPase | 1981 |
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