Ana Acacia Pinheiro Caruso Neves

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biofísica/I Biof

ORCID:

não disponível no Lattes


Formação:

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2008 - 2009

  • Johns Hopkins University

    | Pós-Doutorado | 2006 - 2006

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2006 - 2008

  • Johns Hopkins University

    | Pós-Doutorado | 2004 - 2006

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2003 - 2004

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 1999 - 2003

  • Universidade Federal do Rio de Janeiro

    Farmácia | Graduação | 1995 - 1999
Laboratórios:
Nuvens de Palavras:
Artigos:

(75.00% artigos com DOI)

Titulo DOI Ano
Bradykinin produced during Plasmodium falciparum erythrocytic cycle drives monocyte adhesion to human brain microvascular endothelial cells 10.1016/j.brainres.2023.148669 2024
Toll like receptor 4 mediates the inhibitory effect of SARS-CoV-2 spike protein on proximal tubule albumin endocytosis 10.1016/j.bbadis.2024.167155 2024
Gold nanoparticles reduce tubule-interstitial injury and proteinuria in a murine model of subclinical acute kidney injury 10.1016/j.bbagen.2023.130314 2023
Inhibition of SGLT2 co-transporter by dapagliflozin ameliorates tubular proteinuria and tubule-interstitial injury at the early stage of diabetic kidney disease 10.1016/j.ejphar.2023.175521 2023
Rapamycin treatment induces tubular proteinuria: role of megalin-mediated protein reabsorption 10.3389/fphar.2023.1194816 2023
Is there a role for bradykinin in cerebral malaria pathogenesis? 10.3389/fcimb.2023.1184896 2023
O-Linked GlcNAcylation mediates the inhibition of proximal tubule (Na++K+)ATPase activity in the early stage of diabetes mellitus 10.1016/j.bbagen.2023.130466 2023
The monoterpene 1,8-cineole prevents cerebral edema in a murine model of severe malaria 10.1371/journal.pone.0268347 2022
Albumin Expands Albumin Reabsorption Capacity in Proximal Tubule Epithelial Cells through a Positive Feedback Loop between AKT and Megalin 10.3390/ijms23020848 2022
SARS-CoV-2 spike protein inhibits megalin-mediated albumin endocytosis in proximal tubule epithelial cells 10.1016/j.bbadis.2022.166496 2022
O-GlcNAcylation in Renal (Patho)Physiology 10.3390/ijms231911260 2022
Subclinical Acute Kidney Injury in COVID-19: Possible Mechanisms and Future Perspectives 10.3390/ijms232214193 2022
Eugenol disrupts Plasmodium falciparum intracellular development during the erythrocytic cycle and protects against cerebral malaria 10.1016/j.bbagen.2020.129813 2021
High Doses of Essential Oil of Croton Zehntneri Induces Renal Tubular Damage 10.3390/plants10071400 2021
Megalin-mediated albumin endocytosis in renal proximal tubules is involved in the antiproteinuric effect of angiotensin II type 1 receptor blocker in a subclinical acute kidney injury animal model 10.1016/j.bbagen.2021.129950 2021
Surface megalin expression is a target to the inhibitory effect of bradykinin on the renal albumin endocytosis 10.1016/j.peptides.2021.170646 2021
IL-4 Receptor α Chain Protects the Kidney Against Tubule-Interstitial Injury Induced by Albumin Overload 10.3389/fphys.2020.00172 2020
Effect of cell geometry in the evaluation of erythrocyte viscoelastic properties 10.1103/physreve.101.062403 2020
Plasmodium falciparum maturation across the intra-erythrocytic cycle shifts the soft glassy viscoelastic properties of red blood cells from a liquid-like towards a solid-like behavior 10.1016/j.yexcr.2020.112370 2020
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes 10.1371/journal.ppat.1008230 2020
Malaria in pregnancy regulates P-glycoprotein (P-gp/ Abcb1a ) and ABCA1 efflux transporters in the Mouse Visceral Yolk Sac 10.1111/jcmm.15682 2020
A high salt diet induces tubular damage associated with a pro-inflammatory and pro-fibrotic response in a hypertension-independent manner 10.1016/j.bbadis.2020.165907 2020
Kinins Released by Erythrocytic Stages of Plasmodium falciparum Enhance Adhesion of Infected Erythrocytes to Endothelial Cells and Increase Blood Brain Barrier Permeability via Activation of Bradykinin Receptors 10.3389/fmed.2019.00075 2019
Lithium ameliorates tubule-interstitial injury through activation of the mTORC2/protein kinase B pathway 10.1371/journal.pone.0215871 2019
PKB is a central molecule in the modulation of Na+-ATPase activity by albumin in renal proximal tubule cells 10.1016/j.abb.2019.108115 2019
Dysregulation of placental ABC transporters in a murine model of malaria-induced preterm labor 10.1038/s41598-019-47865-3 2019
O -GlcNAcylation reduces proximal tubule protein reabsorption and promotes proteinuria in spontaneously hypertensive rats 10.1074/jbc.ra118.001746 2018
LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion 10.3389/fmolb.2018.00067 2018
The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury 10.1371/journal.pone.0203836 2018
Targeting Angiotensin II Type-1 Receptor (AT1R) Inhibits the Harmful Phenotype of Plasmodium-Specific CD8+ T Cells during Blood-Stage Malaria 10.3389/fcimb.2017.00042 2017
Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction 10.1038/s41598-017-14642-z 2017
Plasmodium falciparum Invasion and Intraerythrocytic Development are Impaired by 2´, 3´-Dialdehyde Adenosine 10.1016/j.micinf.2017.11.015 2017
New Concepts in Malaria Pathogenesis: The Role of the Renin-Angiotensin System 10.3389/fcimb.2015.00103 2016
Group V Secretory Phospholipase A2 Is Involved in Tubular Integrity and Sodium Handling in the Kidney 10.1371/journal.pone.0147785 2016
Antiplasmodial activity of alkyl-substituted 1,2-dioxetanes against Plasmodium falciparum 10.1016/j.bmcl.2016.08.096 2016
Interaction between bradykinin B2 and Ang-(1-7) Mas receptors regulates erythrocyte invasion by Plasmodium falciparum 10.1016/j.bbagen.2016.07.011 2016
Angiotensin II type-1 receptor (AT1R) regulates expansion, differentiation, and functional capacity of antigen-specific CD8+ T cells 10.1038/srep35997 2016
Lipoxin A4 attenuates endothelial dysfunction during experimental cerebral malaria 10.1016/j.intimp.2014.12.033 2015
Angiotensin II restricted analogs with biological activity in the erythrocytic cycle of Plasmodium falciparum 10.1002/psc.2714 2015
Renin-angiotensin system contributes to naive T-cell migration in vivo 10.1016/j.abb.2015.02.035 2015
Anti-plasmodial activity of Bradykinin and analogs 10.1016/j.bmcl.2015.05.071 2015
Antimalarial Effect of 3-Methoxy-1,2-Dioxetanes on the Erythrocytic Cycle of 10.1111/cbdd.12599 2015
Mesenchymal stromal cell therapy attenuated lung and kidney injury but not brain damage in experimental cerebral malaria 10.1186/s13287-015-0093-2 2015
New linear antiplasmodial peptides related to angiotensin II 2015
IL-4: an important cytokine in determining the fate of T cells 2014
Mice Rescued from Severe Malaria Are Protected against Renal Injury during a Second Kidney Insult 10.1371/journal.pone.0093634 2014
Regulation of Extracellular ATP in Human Erythrocytes Infected with Plasmodium falciparum 10.1371/journal.pone.0096216 2014
5-Lypoxygenase Products Are Involved in Renal Tubulointerstitial Injury Induced by Albumin Overload in Proximal Tubules in Mice 10.1371/journal.pone.0107549 2014
Sepsis-surviving mice are more susceptible to a secondary kidney insult 2013
Protein kinase C-mediated ATP stimulation of Na+-ATPase activity in LLC-PK1 cells involves a P2Y2 and/or P2Y4 receptor 10.1016/j.abb.2013.03.013 2013
Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes 10.1016/j.micinf.2013.02.003 2013
Angiotensin II Is a New Component Involved in Splenic T Lymphocyte Responses during Plasmodium berghei ANKA Infection 10.1371/journal.pone.0062999 2013
Inhibitory Effects of Trypanosoma cruzi Sialoglycoproteins on CD4+ T Cells Are Associated with Increased Susceptibility to Infection 10.1371/journal.pone.0077568 2013
Characterization of ecto-ATPase activity in the surface of LLC-PK1 cells and its modulation by ischemic conditions 10.1016/j.bbagen.2012.09.009 2012
Changes in angiotensin receptors expression play a pivotal role in the renal damage observed in spontaneous hypertensive rats 2011
Impairment of the Plasmodium falciparum Erythrocytic Cycle Induced by Angiotensin Peptides 10.1371/journal.pone.0017174 2011
AT1 receptor-mediated angiotensin II activation and chemotaxis of T lymphocytes 10.1016/j.molimm.2011.05.008 2011
(Na+ + K+)-ATPase Is a Target for Phosphoinositide 3-Kinase/Protein Kinase B and Protein Kinase C Pathways Triggered by Albumin 10.1074/jbc.M111.260737 2011
Giardia lamblia: Characterization of ecto-phosphatase activities 2009
Adenosine deamination to inosine in isolated basolateral membrane from kidney proximal tubule: Implications for modulation of the membrane-associated protein kinase A. 2009
Inhibition of renal Na+-ATPase activity by inosine is mediated by A1 receptor-induced inhibition of the cAMP signaling pathway 10.1016/j.abb.2009.07.003 2009
Giardia lamblia:biochemical characterization of an ecto-ATPase activity 2008
Crosstalk between the signaling pathways triggered by angiotensin II and adenosine in the renal proximal tubules: Implications for modulation of Na(+)-ATPase activity 10.1016/j.peptides.2008.07.004 2008
Entamoeba histolytica: an ecto-phosphatase activity regulated by oxidation-reduction reactions 2007
Mycelial forms of Pseudallescheria boydii present ectophosphatase activities. 10.1007/s00203-007-0232-y 2007
An ectophosphatase activity in Candida parapsilosis influences the interaction of fungi with epithelial cells 2007
IL-4 induces a wide-spectrum intracellular signaling cascade in CD8+ T cells 2007
Entamoeba histolytica: ouabain-insensitive Na(+)-ATPase activity 2007
PKB and Megalin determine the survival or death of renal proximal tubule cells. 2006
Trichomonas vaginalis virulence against epithelial cells and morphological variability: the comparison between a well-established strain and a fresh isolate. 2004
Phosphatase activity on the cell wall of Fonsecaea pedrosoi. 2003
Ecto-phosphatase Activity on the Cell Surface of Crithidia deanei. 2002
Ectonucleotide diphosphohydrolase activity in Crithidea deanei 2002
An Ectonucleotide ATP-diphosphohydrolase Activity in Trichomonas vaginalis Stimulated by Galactose and Its Possible Role in Virulence 2002
Ectonucleotide diphosphohydrolase activities in Entamoeba histolytica 2000
Solubilização de catalisadores desativados em meio contendo fluoreto I: Catalisadores à base de platina 1998
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Involvement of angiotensin II on the modulation of proximal tubule albumin endocytosis by high glucose: role in the genesis of albuminuria in the early stage of diabetic kidney disease 2023
Malaria-induced acute kidney injury in BALB/C mice is associated with progressive glomerular dysfunction 2023
IL-4 receptor signaling protects the renal tubular compartment in adriamycin-induced nephropathy 2023
Protein handling by brain endothelial cells: crucial role on cerebral malaria 2023
Rapamycin treatment induces tubular proteinuria: role of megalin-mediated protein reabsorption 2023
Host immune response participates in malaria acute kidney injury: role of CD8+ T cells 2023
Unraveling the role of bradykinin in cerebral malaria: implications for blood-brain barrier disruption 2023
Albumin overload induced hyper O-Glcnacylation inhibits megalin-mediated albumin endocytosis 2022
Rapamycin treatment induces tubular proteinuria: role of megalin-mediated protein reabsorption 2022
Gold nanoparticles ameliorate renal function and tubule-interstitial injury induced by subclinical acute kidney injury in mice 2022
Host immune response participates in malaria acute kidney injury: role of CD8+ T cells 2022
Impairment of AKT-dependent prolylcarboxypeptidase stability in proximal tubules: involvement on the subclinical acute kidney injury 2022
BK/B2R axis induces caveolae-mediated endocytosis during cerebral malaria 2022
Protective role of IL-4 receptor in adriamycin-induces nephropathy 2022
Protective role of IL-4 receptor in adriamycin-induces nephropathy 2022
Possível papel do receptor de IL-4 no desenvolvimento de nefropatia proteinúrica induzida por adriamicina 2022
AKT/PKB-Megalin Positive Feedback Loop Expands Albumin Endocytosis in Proximal Tubule Cells 2021
Host immune response participates in malaria acute kidney injury: role of CD8+ T cells 2021
Bradicinina inibe a endocitose de albumina mediada por megalina em células do túbulo proximal: envolvimento da via B2R/PKC 2021
Eixo angiotensina-(1-7)/MAS inibe a endocitose de albumina em células LLC-PK1 2021
Proteina Spike do virus SARS-CoV-2 inibe endocitose de albumina em células do túbulo proximal 2021
Host immune response participates in malaria acute kidney injury: role of CD8+ T cells 2021
The treatment with gold nanoparticles inproves renal function in subclinical acute kidney injury model 2021
O-GlcNacylation of proximal tubule (Na+K)ATPase alpha1 subunit is associated with reduced sodium reabsorption in diabetic kidney disease 2021
Megalin-mediated albumin endocytosis in proximal tubule epithelial cells is a target for B2 receptor-mediated bradykinin 2021
Host immune response participates in malaria acute kidney injury: role of CD8+ T cells 2021
Albumin overload impairs albumin endocytosis in proximal tubule cells through increased O-GlcNacylation 2021
Rapamycin induces proteinuria through reduction of proximal tubule megalin- mediated protein endocytosis 2021
Bradykinin increases albumin endocytosis in human brain microvascular endothelial cells during malária infection 2019
BK/B2R axis induces adhesion of monocytes to human brain endothelial cells during infection with Plasmodium falciparum: possible role of PKC and mTOR pathways 2019
PKB is a central molecule in the modulation of Na+-ATPase activity during tubule-interstitial injury induced by albumin overload 2019
Bradykinin mediates adhesion of Plasmodium falciparum infected erythrocytes to endothelial cells and blood-brain barrier disruption 2018
Angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury 2018
Role of kinins generated during malaria infection in monocyte adhesion to endothelial cells 2018
Megalin O-GLCnacylation promotes tubular proteinuria in Spontaneously hypertensive rats 2018
1,8-cineol dampens Plasmodium falciparum ring formation in vitro 2017
1,8-cineol impairs the Intraerytrocytic development of Plasmodium falciparum in vitro 2017
Bradykinin increases adhesion of Plasmodium falciparum-infected red blood cells to endothelial cells 2017
Papel do eixo IL-4/IL-4R na lesão túbulo-intersticial induzida por sobrecarga de proteína 2016
Alterações nas vias de PKB e ERK em córtex renal são observadas em animais espontaneamente hipertensos: possível papel na lesão renal? 2016
Alterações nas vias de PKB e ERK estão associadas com lesão renal em animais espontaneamente hipertensos: correlação com proliferação celular tubular 2015
Differential modulation of mTOR complexes in monocytes adhesion induced by LPS and phorbol ester 2015
Differential modulation of mTOR complexes in monocytes adhesion induced by LPS and phorbol ester 2014
IL-4 regulates protein handling in the kidney: a new role for a well-known cytokine 2014
Modulation of the E-NTPDase activity present in LLC-PK1 cells by purinerginc receptors 2013
The role of renin-angiotensin system in the modulation of monocytes and macrophages (Na++K+)ATPase 2013
Malaria-surviving mice are less susceptible to a secondary kidney insult 2013
Modulation of the Plasmodium falciparum eryhtrocytic stage by cAMP-dependent protein kinase 2011
Angiotensin II/AT1 receptor axis mediates naive T cell homing and activation. 2011
Blockade of Angiotensin Converting Enzyme and AT1 Receptor in T cells During Malaria Infection: Further Mechanisms of T Cell Regulation Mediated by Angiotensin II. 2010
Modulation of the Plasmodium falciparum Blood Stage by Angiotensin Peptides. 2010
Blockade of Angiotensin Converting Enzyme and AT1 Receptor in T cells During Malaria Infection: Further Mechanisms of T Cell Regulation Mediated by Angiotensin II. 2010
New Role of Albumin in Renal Sodium Excretion Under Physiological And Pathophysiological Conditions. 2010
Alteration of renal function in prehypertensive SHR contributes to the establishment of hypertension. 2010
New role for IL-4: Modulation of sodium handling in nephropathy model. 2010
Characterization of E-NTPDase on the surface of LLC-PK1 cells and its modulation by schemic/reperfusion conditions. 2010
Nucleotides promote PKB activation on epithelial cell line LLC-PK1: possible involviment of P2Y1, P2Y2, P2Y4 e P2X7 receptors. 2010
Evaluation of kidney function in Plasmodium berghei ANKA infected mice. 2010
Sepsis-induced renal impairment is exarcerbated by a second renal insult: a role for albumin during acute renal failure pos-sepsis. 2010
AT1 receptor mediated albumin inhibition of Stat3 phosphorylation in proximal tubule cells. 2010
Imbalance in renal angiotensin receptors plays a crucial role during the development of primary hypertension 2009
Albumin modulates PI-3K/PKB, PKC and NF-kB pathways in LLC-PK1 cells: their role in the expression of the (Na++K+)ATPase. 2009
Possible molecular mechanisms involved in kidney malfunction during hypertension 2008
Albumin modulates protein kinases activity in LLC-PK1 cells 2008
Intracellular signaling events mediated by IL-4 in CD8+ T cells 2007
IL-4 induces a wide-spectrum signaling in CD8+ T cells (International Meeting). 2006
IL-4 induces a wide-spectrum signaling in CD8+T cells 2006
UDP-N-Acetylglucosamine:Polypeptide N-Acetylglucosaminyltransferase (ppGlcNAcT) from Crithidea fasciculata 2004
Mycelial forms of Pseudallescheria boydii present an ecto-phosphatase activity 2004
An ecto-ATPase in Entamoeba histolytica and its possible involviment with virulence. 2003
Thrichomonas vaginalis virulence against epithelial cells and morphologic variability: comparison between a well-established strain and a fresh isolate. 2003
Estudo bioquímico de ecto-enzimas presentes em Entamoeba histolytica 2003
Possível envolvimento de ecto-enzimas na citotoxicidade de Entamoeba histolytica 2003
Characterization of an ecto-ATPdiphosphohydrolase activity in Giardia lamblia 2002
Ecto-phosphatase activity in mycelial forms of Fonsecaea pedrosoi 2001
Mycelial forms of Pseudallescheria boydii present an ecto-phosphatase activity 2001
Biochemical and ultrastructural characterization of an ecto-phosphatase activity in mycellial forms of Fonsecaea pedrosoi 2001
Possible involvement of cysteine residues on the enzymatic activity of an ecto-phosphatase present in Entamoeba histolytica. 2001
Characteriation of an ecto-phosphatase activity present in Candida parapsilosis 2001
An ecto-acid phosphatase with properties of an ecto-phosphotyrosine phosphatase activity in Entamoeba histolytica 2000
Modulations of an ecto-ATPdiphosphohydrolase activities of Entamoeba histolytica by lipopolysacharide and by carbohydrates 2000
Recovery of precious metals of monometallic spent X/Al2O3 catalysis (X=Cu, Pt and Pd) in a fluoride containing medium. 1999
Endosymbiont induces the expression of an ecto-ATPase in Crithidia deanei. 1998
Ecto-phosphatase activities present on the surface of Entamoeba histolytica. 1998
Natural iInhibitor protein (IF1) protects mitochondrial F0F1-ATPase against Inactivation by urea. 1998
Biochemical characterization and cytochemical localization of an ecto-ATPase in Crithidia deanei. 1998
Recuperação do metal nobre de catalisadores monometálicos Pt/Al2O3 e Pd/Al2O3 1998
Valorização do uso de fluoreto como agente de solubilização de catalizadores desativados'a base de platina. 1997
Separação de fluorocomplexos de Pt-Sn-In-Fe-Al 1997
Estudo da distribuição de espécies aniônicas em resina piridínica. 1997
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