Jose Roberto Lapa e Silva

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Medicina

Departamento:

Departamento de Clínica Médica/FM

ORCID:

https://orcid.org/0000-0003-3116-0253


Formação:
  • Institut Pasteur de Paris

    | Pós-Doutorado | 1999 - 1999
  • Institut Pasteur de Paris

    | Pós-Doutorado | 1991 - 1992
  • University of London

    National Heart and Lung Institute | Doutorado | 1987 - 1991
  • Universidade Federal do Rio de Janeiro

    Tisiologia e Pneumologia | Mestrado | 1977 - 1982
  • Universidade Federal do Rio de Janeiro

    Medicina | Graduação | 1968 - 1973
Laboratórios:
Nuvens de Palavras:
Artigos:
Nenhum artigo cadastrado
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
The role of BCG vaccine on airway and lung parenchima remodeling in a murine model of chronic allergic inflammation 2010
Case report: intrabronchial instillation of bone marrow derived mononuclear cells in silicotic patients 2010
Patterns of C-Reactive Protein Response to Antibiotic Therapy in Severe Community-Acquired Pneumonia Patients: A Cohort Study 2009
Medical Students at Risk for Nosocomial Tuberculosis Infection 2009
Artificial Neural Networks (ANN) To Predict Pulmonary Tuberculosis Diagnosis in Hospitals in Rio De Janeiro, Brazil 2009
[Poster Board #E15] Novel Tests in Parallel for Diagnosing Tuberculous Pleuritis 2009
The importance of frequency and plateau pressure during sigh recruitment manoever 2008
Impact f smoke inhalation injury, age and body surface area burned in patients with severe facial burns 2008
Computational analysis of the M. tuberculosis International Spolygotyping Database suggests that certain spoligopatterns may be derived from mixed infections 2008
Molecular Characterization of Interleukin-10 Proximal Promoter Region in Brazilian Subjects 2007
Molecular Analysis of Promoter Region of IFN-g coding gene in Brazilian Subjects with tuberculosis 2007
Is the severity pf tuberculosis different when patients are infected by strains of M. tuberculosis belonging to diverse spoligotyping families? 2007
CXCR3 and CCR5 chemokines in the induced sputum of patients with COPD 2007
Infection with multiple M. tuberculosis strains could lead to a false interpretation of the genotyping methods 2007
Genetic susceptibility to TB M. tuberculosis in Brazilian subjects: the possible role of Arg753Gln polymorphism in the human Toll-like Receptor 2 gene 2007
Increased levels of sputum IL-10 at the end of anti-tuberculosis (TB) chemotherapy is a marker for relapse 2007
Bronchial epithelium desquamation is na early prognostic sign of fatal outcome in severe facial burns 2007
. Immunologic abnormalities in young children with prior pulmonary and miliary/ meningeal tuberculosis 2006
Analysis of immunomodulatory molecules in lung cells of tuberculosis patients before and after chemotherapy by RT-PCR 2006
. Influence of variants alleles of mannose binding lectin (MBL) in the susceptibility to Mycobacterium tuberculosis infection 2006
Expression of costimulatory molecules on active tuberculosis (TB). 2006
. Is induced sputum a safe method to be used in COPD patients? 2006
TLR-4 expression after in vitro LPS stimulation of sputum cells from severe asthmatics does not change despite increases in CD14 expression 2006
PAF-aceylhydrolase activity in ventilator-associated pneumonia 2006
Pro-inflammatory cytokines fail to predict progrnosis in in ventilator-associated pneumonia 2006
Role of regulatory cytokines and inducible nitric oxide synthase (NOS) in active tuberculosis 2005
M. tuberculosis strains harboring a novel large chromossomal deletio (RDrio) are infectious, transmissible and the predominant cause of tuberculosis in Rio de Janeiro, Brazil 2005
Cytokine expression in the lungs of tuberculous patients before and after standard chemotherapy 2005
In vitro LPS stimulation of sputum cells from severe asthmatics increases CD14 expression 2005
Quantitative analysis of small airway muscle fibers in COPD, smoking, and non-smoking subjects 2005
Quantitative analysis of CD4+, CD8+, CD4+/CD8+ small airways in COPD, smoking, and non-smoking subjects 2005
Assessment of airway inflammationg using induced sputum in COPD, smoking, and non-smoking subjects 2005
Lung Tissue Mechanics and Extracellular Matrix Remodeling in a Murine Model of Chronic Asthma Am 2004
PCR-Based Genotypic Evaluation of M. tuberculosis Isolates from Rio de Janeiro, Brazil 2004
Cytokine Message in the Lungs of Tuberculosis Patients before and after Chemotherapy 2004
Quantitative Analysis of Elastic Fibers in COPD, Smoking, and Non-Smoking Subjects. 2004
Immunomodulatory cytokines in the pathogenesis of tuberculosis 2003
Extended freeze dried Mycobacterium bovis BCG reduce metaplasia, bronchial hyperreactivity and dendritic cell recruitment to the lungs of allergic mice 2003
. IgA and IgG immune response against the antigen P-90 in pulmonary tuberculosis patients 2003
Cervical immunity response induced by HPV and the influence of HIV-1 co-infection. 2002
BCG vaccination results in early recruitment of dendritic cells and upregulation of co-stimulatory molecules in mice with high TH2 background 2001
Non-smoking quarry mine workers exhibit signs of chronic bronchitis independently of the degree of exposure to silica dust 2001
Role of Transforming Growth Factor (TGF)-b receptors in tuberculous limphadenitis in HIV-infected or not patients 2000
Effects of BCG vaccination on the development of allergic inflammation and bronchial hyper-responsiveness (BHR) in newborn hyper-IgE BP2 mice 2000
Failure of granulocyte depletion to suppress mucin production in a murine model of allergy 2000
Inducible Nitric Oxide Synthase (Nos2) Expression By Sputum Inflammatory Cells Of Asthmatics: Modulation By Beclomethasone Dipropionate. 1999
Evaluation Of Bronchial Inflamation In Quarry Mine Workers In Rio de Janeiro By Induced Sputum 1999
Modulation Of Eosinophillic Bronchitis In Asthmatics By Inhaled Beclomethasone Dipropionate (Bdp) Is Accompanied By Increased Neutrophilia 1999
Levels Of Cytokines And Reactive Nitrogen Intermediates In Tuberculous Pleural Effusion 1999
Granuloma Formation Defect In Lymph Node Of Hiv-1 Tuberculosis Patients 1998
Phenotype Of Alveolar Mononuclear Phagocytes From Hiv-1 Infected Patients With Active Tuberculosis 1998
Transforming Growth Factor (Tgf)-B Ligand And Receptoras In Pulmonary Tuberculosis. 1998
Tuberculosis Conversion Among Health Care Workers In A General Hspital Of Rio de Janeiro, Brazil. Final Results. 1998
Increased Expression Of Fas And Fas-Ligand In The Bronchial Epithelium From Asthmatics 1997
Tuberculosis Infectivity Among Close Contacts Of Pulmonary Tuberculosis Patients In Rio de Janeiro, Brazil 1997
The Usefulness Of Induced Sputum (Is) For Diagnosis Of Pulmonary Tuberculosis (Pt) In Aids Reference Center, In Rio de Janeiro (Rj), Brazil: Preliminary Results. 1997
Increased Tumor Factor (Tnf)- A Levels In Bronchoalveolar Lavage Fluid In Patients With Tuberculosis And Hiv-1 Infection. 1997
Expression Of Hla-Dr By Alveolar Macrophages From Affected Areas Of Tuberculosis Patients Co-Infected With Hiv 1997
Cytokine Expression In Lung Cells From Patients With Tuberculosis And Aids. 1997
Inducible Nitric Oxide Synthase And Cytokine Expression In Lung Cells From Patients With Tuberculosis 1997
The Role Of Neutrophils And Eosinophils In Human Bronchiectasis 1997
Fk506 Down-Regulates A-4 Integrin Expression In The Lungs Of Sensitized Guinea Pigs 1996
Effect Of Salmeterol An Antigen-Induced T-Lymphocyte And Eosinophil Infiltration Into The Airways Of Sensitised Guinea Pigs. 1996
Effects Of Capsaicin Treatment On Chronic Airway Inflammation Induced By Repeated Antigen Exposure In Guinea Pigs 1996
Drug Resistant Tuberculosis In A General Hospital - Aids Reference Center, In Aids Reference Center, In Rio de Janeiro, Brazil 1996
Effect Of Salmeterol An Antigen-Induced T-Lymphocyte And Eosinophil Infiltration Into The Airways Of Sensitised Guinea Pigs. 1996
Fk506 Down-Regulates A-4 Integrin Expression In The Lungs Of Sensitized Guinea Pigs. 1996
Fk506 Down-Regulates A-4 Integrin Expression On Eosinophils In Sensitized Guinea Pigs. 1996
Tuberculin Skin Test Conversion Among Close Contacts Of Pulmonary Tuberculosis Patients, Infected Or Not By Hiv 1996
. Kinetics Of Antigen-Induced Changes In The Airways Of Aerosol Sensitized Guinea Pigs. 1995
Markers Of Airway Inflammation In Guinea Pig Immunized With Toluene Diisocyanate 1995
Neurokinin Depletion Attenuates Inflammatory Pulmonary Response To Repeated Antigen Exposures In Guinea Pigs 1995
Phenotype Of Alveolar Macrophages In The Bronchoalveolar Lavage Fluid Of Tuberculosis Patients 1995
A Subpopulation Of Th0/Th2 T-Lymphocytes Is Expanded In The Bronchoalveolar Lavage Fluid Of Tuberculosis Patients. 1995
Kinetics Of Vla-4 Changes In The Airways Of Aerosol Sensitized Guinea Pigs 1995
Modulation Of Bronchial Inflammation In Sensitized Guinea Pigs By Intra-Tracheally Administered Fluticasone Propionate And Dexametasone. 1995
Effect Of Salmeterol On Antigen-Induced T-Lymphocyte And Eosinophil Infiltration Into The Airways Of Sensitised Guinea Pigs. 1995
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