Jose Roberto Lapa e Silva

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Medicina

Departamento:

Departamento de Clínica Médica/FM

ORCID:

https://orcid.org/0000-0003-3116-0253


Formação:

  • Institut Pasteur de Paris

    | Pós-Doutorado | 1999 - 1999

  • Institut Pasteur de Paris

    | Pós-Doutorado | 1991 - 1992

  • University of London

    National Heart and Lung Institute | Doutorado | 1987 - 1991

  • Universidade Federal do Rio de Janeiro

    Tisiologia e Pneumologia | Mestrado | 1977 - 1982

  • Universidade Federal do Rio de Janeiro

    Medicina | Graduação | 1968 - 1973
Laboratórios:
Nuvens de Palavras:
Artigos:

(72.11% artigos com DOI)

Titulo DOI Ano
Development and validation of a machine learning model to predict the use of renal replacement therapy in 14,374 patients with COVID-19 10.1016/j.jcrc.2023.154480 2024
Isoniazid Monoresistance and Antituberculosis Treatment Outcome in Persons With Pulmonary Tuberculosis in Brazil 10.1093/ofid/ofad691 2024
Impact of Subsyndromal Delirium Occurrence and Its Trajectory during ICU Stay 10.3390/jcm11226797 2023
Factors associated with non-completion of TB preventive treatment in Brazil 10.5588/ijtld.22.0571 2023
The five times sit-to-stand test: safety, validity and reliability with critical care survivors?s at ICU discharge 10.1186/s40945-022-00156-z 2023
Gait speed, muscle strength, and functional status predict 30-day unplanned hospital readmission of critical care survivors 10.1002/pri.2001 2023
A multi-center, prospective cohort study of whole blood gene expression in the tuberculosis-diabetes interaction 10.1038/s41598-023-34847-9 2023
Telemedicine Support for Primary Care Providers versus Usual Care in Patients with Heart Failure: Protocol of a Pragmatic Cluster Randomised Trial within the Brazilian Heart Insufficiency with Telemedicine (BRAHIT) Study 10.3390/ijerph20115933 2023
Serum from patients with asthma potentiates macrophage phagocytosis and human mesenchymal stromal cell therapy in experimental allergic asthma 10.1016/j.jcyt.2023.05.014 2023
The effect of BCG vaccination on infection and antibody levels against SARS-CoV-2-The results of ProBCG: a multicenter randomized clinical trial in Brazil 10.1016/j.ijid.2023.02.014 2023
Anemia and anti-tuberculosis treatment outcome in persons with pulmonary tuberculosis: A multi-center prospective cohort study 10.1016/j.jiph.2023.04.009 2023
SNPs, adipokynes and adiposity in children with asthma 10.1080/02770903.2022.2077218 2023
Translation, cross-cultural adaptation and validation of the Stanmore System for patients with foot drop due to leprosy in Brazil 10.47276/lr.94.3.218 2023
Research, Innovation, and National Production of Strategic Inputs for Tuberculosis Elimination in Brazil: Contributions from the REDE-TB 10.1590/0037-8682-0518-2023 2023
Delirium severity and outcomes of critically ill COVID-19 patients 10.5935/2965-2774.20230170-en 2023
Recurrent WWTR1 S89W mutations and Hippo pathway deregulation in clear cell carcinomas of the cervix 10.1002/path.5910 2022
Nitazoxanide in Patients Hospitalized With COVID-19 Pneumonia: A Multicentre, Randomized, Double-Blind, Placebo-Controlled Trial 10.3389/fmed.2022.844728 2022
Tuberculosis: a deadly and neglected disease in the COVID-19 era 10.36416/1806-3756/e20220056 2022
Thesis and dissertations examining tuberculosis in Brazil between 2013 and 2019: an overview 10.1590/0037-8682-0198-2022 2022
Determinants of losses in the tuberculosis infection cascade of care among children and adolescent contacts of pulmonary tuberculosis cases: A Brazilian multi-centre longitudinal study 10.1016/j.lana.2022.100358 2022
EBUS-TBNA versus mediastinoscopy for mediastinal staging of lung cancer: a cost-minimization analysis 10.36416/1806-3756/e20220103 2022
Safety and effectiveness of bronchial thermoplasty after 10 years in patients with persistent asthma (BT10+): a follow-up of three randomised controlled trials 10.1016/S2213-2600(20)30408-2 2021
The Effect of Diabetes and Prediabetes on Transmission to Close Contacts 10.1093/infdis/jiab264 2021
Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema 10.3389/fcell.2021.661385 2021
Pre-Treatment Neutrophil Count as a Predictor of Antituberculosis Therapy Outcomes: A Multicenter Prospective Cohort Study 10.3389/fimmu.2021.661934 2021
Rapid On-Site Evaluation by Endosonographer of Endoscopic Ultrasound Fine-Needle Aspiration of Solid Pancreatic Lesions 10.1097/MPA.0000000000001846 2021
Determinants of losses in the latent tuberculosis infection cascade of care in Brazil 10.1136/bmjgh-2021-005969 2021
Brazilian Tuberculosis Research Network: 20 years of history in the fight against Tuberculosis 10.36416/1806-3756/e20210341 2021
Perceptions of plagiarism among PhDs across the sciences, engineering, humanities, and arts: Results from a national survey in Brazil 10.1080/08989621.2021.2018306 2021
Prevalence and Clinical Profiling of Dysglycemia and HIV Infection in Persons With Pulmonary Tuberculosis in Brazil 10.3389/fmed.2021.804173 2021
The Effect of Diabetes and Prediabetes on Antituberculosis Treatment Outcomes: A Multicenter Prospective Cohort Study 10.1093/infdis/jiab427 2021
Novel stepwise approach to assess representativeness of a large multicenter observational cohort of tuberculosis patients: The example of RePORT Brazil 10.1016/j.ijid.2020.11.140 2021
Autologous bone marrow-derived mononuclear cell therapy in three patients with severe asthma 10.1186/s13287-020-01675-x 2020
Oncogenic properties and signaling basis of the fusion gene 10.1002/ijc.33040 2020
A summary of the proceedings of a meeting on the treatment of latent tuberculosis infection in target populations in Brazil 10.36416/1806-3756/e20200023 2020
Endobronchial ultrasound-guided transbronchial needle aspiration versus mediastinoscopy for mediastinal staging of lung cancer: A systematic review of economic evaluation studies 10.1371/journal.pone.0235479 2020
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response 2020
Increased Frequency of Memory CD4+ T-Cell Responses in Individuals With Previously Treated Extrapulmonary Tuberculosis 10.3389/fimmu.2020.605338 2020
Early use of nitazoxanide in mild Covid-19 disease: randomised, placebo-controlled trial 10.1183/13993003.03725-2020 2020
An Uncommon Lung Neoplasm in a Young Patient: Diagnostic Challenges 10.12659/AJCR.926038 2020
Factors associated with mortality in severe community-acquired pneumonia: A multicenter cohort study 10.1016/j.jcrc.2018.11.024 2019
Qualidade e relevância da produção científica nas ciências da saúde: práticas de citação na área de pneumologia. Parte II 2019
Genetic diversity and molecular epidemiology of Mycobacterium tuberculosis in Roraima State, Brazil 10.4269/ajtmh.19-0324 2019
Endobronchial ultrasound-guided transbronchial needle aspiration versus mediastinoscopy for mediastinal staging of lung cancer 10.1097/MD.0000000000017242 2019
RELATIONSHIP OF ANTI-TUBERCULOSIS DRUG-INDUCED LIVER INJURY AND GENETIC POLYMORPHISMS IN CYP2E1 AND GST 10.1016/j.bjid.2019.09.003 2019
Polymorphisms in Interferon Pathway Genes and Risk of Mycobacterium tuberculosis Infection in Contacts of Tuberculosis Cases in Brazil 10.1016/j.ijid.2019.12.013 2019
Patterns of C-reactive protein ratio response to antibiotics in pediatric sepsis: A prospective cohort study 10.1016/j.jcrc.2017.11.018 2018
Clonal expansion across the seas as seen through CPLP-TB database: A joint effort in cataloguing Mycobacterium tuberculosis genetic diversity in Portuguese-speaking countries 10.1016/j.meegid.2018.03.011 2018
Impact of smoking on sputum culture conversion and pulmonary tuberculosis treatment outcomes in Brazil: a retrospective cohort study 10.1590/s1806-37562017000000161 2018
Planning and understanding the intensive care network in the State of Rio de Janeiro (RJ), Brazil: a complex societal problem 10.5935/0103-507x.20180053 2018
Asthma mortality in Brazil, 1980-2012: a regional perspective 10.1590/s1806-37562017000000235 2018
Polymorphisms in TLR4 and TNFA and Risk of Mycobacterium tuberculosis Infection and Development of Active Disease in Contacts of Tuberculosis Cases in Brazil: A Prospective Cohort Study 10.1093/cid/ciy1001 2018
QUALIDADE E RELEVÂNCIA DA PRODUÇÃO CIENTÍFICA NAS CIÊNCIAS DA SAÚDE: PRÁTICAS DE CITAÇÃO NA ÁREA DE PNEUMOLOGIA 2018
Combined Bone Marrow-Derived Mesenchymal Stromal Cell Therapy and One-Way Endobronchial Valve Placement in Patients with Pulmonary Emphysema: A Phase I Clinical Trial 10.1002/sctm.16-0315 2017
Outcomes of subsyndromal delirium in ICU: a systematic review and meta-analysis 10.1186/s13054-017-1765-3 2017
Addressing the tuberculosis-depression syndemic to end the tuberculosis epidemic 10.5588/ijtld.16.0584 2017
Patterns of C-reactive protein ratio predicts outcomes in healthcare-associated pneumonia in critically ill patients with cancer 10.1016/j.jcrc.2017.07.021 2017
DEMAND FORECAST AND OPTIMAL PLANNING OF INTENSIVE CARE UNIT (ICU) CAPACITY 10.1590/0101-7438.2017.037.02.0229 2017
Mesenchymal stromal cell therapy in COPD: from bench to bedside 10.2147/COPD.S146671 2017
Functional analysis of polymorphisms in the COX-2 gene and risk of lung cancer 10.3892/mco.2017.1167 2017
Brazilian Response to Global End TB Strategy : The National Tuberculosis Research Agenda 10.1590/0037-8682-0330-2015 2016
Difficulties in access and estimates of public beds in intensive care units in the state of Rio de Janeiro 10.1590/s1518-8787.2016050005997 2016
Rede Brasileira de Pesquisa em Tuberculose - REDE TB 2016
Endobronchial ultrasound in real life: primary diagnosis and mediastinal staging of lung cancer in patients submitted to thoracic surgery 10.1186/s12890-016-0264-7 2016
Transcriptomic Biomarkers for Tuberculosis: Evaluation of DOCK9. EPHA4, and NPC2 mRNA Expression in Peripheral Blood 10.3389/fmicb.2016.01586 2016
Use of biomarkers in pediatric sepsis: literature review 10.5935/0103-507x.20160080 2016
Clinical Outcomes and Microbiological Characteristics of Severe Pneumonia in Cancer Patients: A Prospective Cohort Study 10.1371/journal.pone.0120544 2015
Pilot safety study of intrabronchial instillation of bone marrow-derived mononuclear cells in patients with silicosis 10.1186/s12890-015-0061-8 2015
Developments in Impact Assessment of New Diagnostic Algorithms for Tuberculosis Control 10.1093/cid/civ580 2015
Impact of Pre-Analytical Variables on Cancer Targeted Gene Sequencing Efficiency 10.1371/journal.pone.0143092 2015
Pulmonary Tuberculosis 10.1155/2013/645747 2013
Bronchial thermoplasty: Long-term safety and effectiveness in patients with severe persistent asthma 10.1016/j.jaci.2013.08.009 2013
Impact of Bacillus Calmette-Guérin Moreau vaccine on lung remodeling in experimental asthma 10.1016/j.resp.2013.07.025 2013
Interleukin-10 and interferon-gamma patterns during tuberculosis treatment: possible association with recurrence [Short communication] 10.5588/ijtld.11.0707 2012
Novos aspectos da patogenia da tuberculose 2012
Diretrizes para o Manejo da Asma da Sociedade Brasileira de Pneumologia e Tisiologia 2012
Evaluation of MCM-2 Expression in TMA Cervical Specimens 10.1371/journal.pone.0032936 2012
Mycobacterium tuberculosis-induced neutrophil ectosomes decrease macrophage activation 10.1016/j.tube.2012.02.007 2012
Mycobacterium tuberculosis spoligotypes that may derive from mixed strain infections are revealed by a novel computational approach 10.1016/j.meegid.2011.08.028 2012
An evaluation of p16INK4a expression in cervical intraepithelial neoplasia specimens, including women with HIV-1 10.1590/s0074-02762012000500001 2012
Tuberculosis caused by RDRio Mycobacterium tuberculosis is not associated with differential clinical features 10.5588/ijtld.11.0709 2012
Patterns of C-reactive protein ratio response in severe community-acquired pneumonia: a cohort study 10.1186/cc11291 2012
Feasibility study of a smoking cessation intervention in Directly Observed Therapy Short-Course tuberculosis treatment clinics in Rio de Janeiro, Brazil 10.1590/s1020-49892012001400009 2012
Medical students at risk of nosocomial tuberculosis 10.1016/j.jhin.2010.07.021 2011
Impact of systemic corticosteroids on the clinical course and outcomes of patients with severe community-acquired pneumonia: A cohort study 10.1016/j.jcrc.2010.07.014 2011
Persistence of effectiveness of bronchial thermoplasty in patients with severe asthma 10.1016/j.anai.2011.03.005 2011
The impact of coagulation parameters on the outcomes of patients with severe community-acquired pneumonia requiring intensive care unit admission 10.1016/j.jcrc.2011.02.001 2011
New regimens for reducing the duration of treatment of drug-susceptible pulmonary tuberculosis 10.1002/ddr.20456 2011
Promotion of a down-modulated lung immune state may be a strategy by M. tuberculosis to foster active disease and persistence 2010
Cortisol levels and adrenal response in severe community-acquired pneumonia: A systematic review of the literature 10.1016/j.jcrc.2010.03.004 2010
Células inflamatórias e seus mediadores na patogênese da DPOC 2009
Análise do lavado broncoalveolar em vítimas de queimaduras faciais graves 10.1590/s1806-37132009000400008 2009
Tuberculosis is associated with a down-modulatory lung immune response that impairs Th1-type immunity 10.4049/jimmunol0801212 2009
Uses of tuberculosis mortality surveillance to identify programme errors and improve database reporting 2009
Effects of frequency and inspiratory plateau pressure during recruitment manoeuvres on lung and distal organs in acute lung injury 10.1007/s00134-009-1439-y 2009
Symptoms prevalence among office workers of a sealed versus a non-sealed building: Associations to indoor air quality 10.1016/j.envint.2009.07.005 2009
BCG como modulador do processo inflamatorio na asma 2009
III Brazilian Thoracic Association Guidelines on tuberculosis 2009
Quality of life of asthmatic adolescents: assessment of asthma severity, comorbidity, and life style 10.2223/jped.1957 2009
Cell-cycle and suppressor proteins expression in uterine cervix in hiv/hpv co-infection: comparative study by tissue micro-array (tma) 10.1186/1471-2407-8-289 2008
Role of IFN-? +874 T/A single nucleotide polymorphism in the tuberculosis outcome among Brazilians subjects 10.1007/s11033-007-9123-1 2008
CXCR3 and CCR5 chemokines in the induced sputum from patients with COPD 10.1378/chest.07-0393 2008
Mycobacterium bovis BCG killed by extended freeze-drying reduces airway hyperresponsiveness in 2 animal models 10.1016/j.jaci.2007.09.033 2008
Randomized comparison of ciclesonide 160 and 640?g/day in severe asthma 10.1016/j.pupt.2007.11.002 2008
Application of Sensitive and Specific Molecular Methods To Uncover Global Dissemination of the Major RDRio Sublineage of the Latin American-Mediterranean Mycobacterium tuberculosis Spoligotype Family 10.1128/JCM.02231-07 2008
Doenças negligenciadas: Doenças Micobacterianas 2008
TWO-STEP TUBERCULIN SKIN TEST AND BOOSTER PHENOMENON PREVALENCE AMONG BRAZILIAN MEDICAL STUDENTS 2008
Inflamação crônica na asma brônquica 2008
Adrenal Response in Severe Community-Acquired Pneumonia: Impact on Outcomes and Disease Severity 10.1378/chest.08-1382 2008
The presence of a booster phenomenon among contacts of active pulmonary tuberculosis cases: a retrospective cohort 10.1186/1471-2458-7-38 2007
The correlation between asthma control and health status: the GOAL study 2007
Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease 2007
Perfil celular do escarro induzido e sangue periférico na doença pulmonar obstrutiva crônica 10.1590/s1806-37132007000500005 2007
Avaliação quantitativa das fibras elásticas na doença pulmonar obstrutiva crônica 10.1590/s1806-37132007000500004 2007
Lung production of platelet-activating factor acetylhydrolase in oleic acid-induced acute lung injury? 10.1016/j.plefa.2007.04.001 2007
Immune Function in Young Children With Previous Pulmonary or Miliary/Meningeal Tuberculosis and Impact of BCG Vaccination 10.1542/peds.2006-3150 2007
Low expression of antigen-presenting and costimulatory molecules by lung cells from tuberculosis patients 10.1590/S0100-879X2006005000141 2007
Duas décadas de pesquisa em tuberculose no Brasil: estado da arte das publicações científicas 2007
Discovery of a Novel Mycobacterium tuberculosis Lineage That Is a Major Cause of Tuberculosis in Rio de Janeiro, Brazil 10.1128/JCM.01394-07 2007
Entendendo os mecanismos relacionados à obesidade e asma 2007
Immune factors involved in the cervical immune response in the HIV/HPV co-infection 10.1136/jcp.2007.047290 2007
<a name="home"></a>Protective effects of phosphodiesterase inhibitors on lung function and remodeling in a murine model of chronic asthma 10.1590/S0100-879X2006000200016 2006
In situ detection of SOCS and cytokine expression in the uterine cervix from HIV/HPV coinfected women 10.1016/j.yexmp.2006.01.002 2006
Cellular and biochemical bases of chronic obstructive pulmonary disease]]> 10.1590/S1806-37132006000900011 2006
Distribution of Immune Cell Subsets and Cytokine-Producing Cells in the Uterine Cervix of Human Papillomavirus (HPV)-Infected Women 10.1097/01.pas.0000143309.81183.6c 2005
Bronchial hyperresponsiveness and analysis of induced sputum cells in Crohn's disease 10.1590/s0100-879x2005000200007 2005
Lung Parenchyma Remodeling in a Murine Model of Chronic Allergic Inflammation 10.1164/rccm.200408-997OC 2005
Constitutive expression of IL-2Rbeta chain and its effects on IL-2-induced vascular leak syndrome 10.1016/j.cyto.2005.10.006 2005
Immunoglobulin A (IgA) and IgG Immune Responses against P-90 Antigen for Diagnosis of Pulmonary Tuberculosis and Screening for Mycobacterium tuberculosis Infection 10.1128/CDLI.11.1.94-97.2004 2004
Small bowel of patients with asthma and allergic rhinitis: absence of inflammation despite the presence of major cellular components of allergic inflammation 2004
Down-Modulation of Lung Immune Responses by Interleukin-10 and Transforming Growth Factor   (TGF- ) and Analysis of TGF-  Receptors I and II in Active Tuberculosis 10.1128/IAI.72.5.2628-2634.2004 2004
NK Cells and Polymorphonuclear Neutrophils Are Both Critical for IL-2-Induced Pulmonary Vascular Leak Syndrome 10.4049/jimmunol.172.12.7661 2004
Modulação da expressão da sintase induzível de óxido nítrico pelo glicocorticóide inalado na asma brônquica 2004
O ressurgimento da tuberculose e o impacto do estudo da imunopatologia pulmonar. 2004
Distribuição de Polimorfismos de Base única (SNPs) no gene de TNF-alfa (-238/-308) entre pacientes com TB e outras pneumopatias: marcadores genéticos de susceptibilidade a ocorrência de TB? 10.1590/S1806-37132004000400012 2004
Immunohistochemical Study of Intestinal Eosinophils in Inflammatory Bowel Disease 10.1097/00004836-200302000-00006 2003
Dendritic cells recruited to the lung shortly after intranasal delivery of Mycobacterium bovis BCG drive the primary immune response towards a type 1 cytokine production 10.1046/j.1365-2567.2003.01609.x 2003
Elicitation of the allergic reaction in beta-lactoglobulin-sensitized Balb/c mice: biochemical and clinical manifestations differ according to the structure of the allergen used for challenge 10.1046/j.1365-2222.2003.01613.x 2003
Pneumonia Asiátia ou SRAG, síndrome respiratória aguda grave 2003
The Mycobacterium tuberculosis Complex-Restricted Gene cfp32 Encodes an Expressed Protein That Is Detectable in Tuberculosis Patients and Is Positively Correlated with Pulmonary Interleukin-10 10.1128/iai.71.12.6871-6883.2003 2003
TNF-alfa e a conversão ao teste tuberculínico: papel dos polimorfismos de base única -238/-308 2003
The usefulness of serum adenosine deaminase 2 (ADA2) activity in adults for the diagnosis of pulmonary tuberculosis 10.1053/rmed.2001.1273 2002
Viragem da prova tuberculínica entre profissionais da área de saúde em um hospital universitário referência para AIDS, no Rio de Janeiro, Brasil 2002
Another brick in the wall 2002
Pulmão RJ: o novo desafio 2002
III Consenso Brasileiro no Manejo da Asma 2002
Effects of Mycobacterium bovis BCG on the development of allergic inflammation and bronchial hyperresponsiveness in hyper-IgE BP2 mice vaccinated as newborns 10.1016/s0264-410x(00)00345-5 2001
Review of current literature: Chronic Obstrutive Pulmonary Disease. Pathogenesis to treatment, Novartis Foundation, Wiley, UK, 2001 2001
Mycobacterium tuberculosis lipid antigens: use of multi-antigen based enzyme immunoassay for free and complex dissociated antibodies 2000
Endotoxins, asthma, and allergic immune responses 10.1016/s0300-483x(00)00289-4 2000
A asma como doença inflamatória 2000
Modulation of experimental bronchopulmonary allergy by anti-inflammatory compounds. 2000
O método do escarro induzido no estudo da asma brônquica - revisão. 2000
Prevention Of Antigen-Induced Bronchial Hyperreactivity And Airway Inflammation In Sensitized Guinea-Pigs By Tacrolimus 1999
A importância da crítica na ciência 1999
Óxido nítrico e asma brônquica- revisão 1999
A genome-wide screen for asthma-associated quantitative trait loci in a mouse model of allergic asthma 10.1093/hmg/8.4.601 1999
Tuberculosis And H I V: Renewed Challenge. 1998
Apoptosis, Proliferation, and Expression of Bcl-2, Fas, and Fas Ligand in Bronchial Biopsies from Asthmatics 10.1165/ajrcmb.19.5.3166 1998
Immune Response During HIV and Tuberculosis Co-infection 10.1590/s0074-02761998000300023 1998
Alterações Imunológicas Pulmonares Nas Doenças Intersticiais 1998
I I Consenso Brasileiro No Manejo da Asma 1998
Role of eosinophilic airway inflammation in models of asthma 10.1590/S0074-02761997000800032 1997
Tuberculose Ganglionar Em Pacientes Co-Infectados Pelo H I V-1. 1997
Effects Of Capsaicin Treatment On Airway Inflammation Induced By Chronic Antigen Exposure In Guinea Pigs 10.1164/ajrccm.155.5.9154886 1997
The Use Of Induced Sputum To Follow Asthmatics In The Clinical Practice (Editorial). 1997
Pesquisa Científica e Pneumologia No Brasil. 1997
Phenotypes Of Lung Mononuclear Phagocytes In The Bronchoalveolar Lavage Fluid Of Hiv Seronegative Tuberculosis Patients: Evidence For New Recruitment And Cell Activati 1996
Phenotypic analysis of intestinal non-inflamed mucosa in Crohn-s disease 10.1097/00042737-199606000-00013 1996
Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis 10.1084/jem.183.5.2293 1996
Asthma Research In Brazil (Editorial). 1996
Inflammatory events in the blood and airways of guinea pigs immunized to toluene diisocyanate. 10.1164/ajrccm.154.1.8680681 1996
Trypanosoma Cruzi: Both Chemically Induced And Triatomine-Derived Metacyclic Forms Of Trypomastigotes Cause The Same Immunological Disturbances In The Infected Mamalian Host 1995
Modulation of the bronchial inflammation in sensitized guinea-pigs by FK506, nedocromil sodium and dexamethasone 10.1183/09031936.95.08081321 1995
Cells and Cytokines in Chronic Bronchial Infection 10.1111/j.1749-6632.1994.tb39816.x 1994
Antibody to very late activation antigen 4 prevents antigen-induced bronchial hyperreactivity and cellular infiltration in the guinea pig airways 10.1084/jem.180.3.795 1994
Emergence Of T-Lymphocytes, Eosinophils And Dendritic Cells In The Bronchi Of Actively Sensitized Guinea Pigs After Antigenic Challenge. 1994
Sintomas Respiratórios e Testes Espirográficos dos Funcionários de Uma Pedreira No Rio de Janeiro. 1994
Bronquiectasia 1994
Immunohistochemical characterization of T lymphocytes and eosinophils in the bronchial wall of actively sensitized guinea pigs 10.1378/chest.103.2.130S 1993
Immunopathologic Alterations in the Bronchi of Immunized Guinea Pigs 10.1165/ajrcmb/9.1.44 1993
Asma brônquica. Revisão e Atualização 1993
Booster-Dependent Alterations of the Subsets of T Lymphocytes and Eosinophils in the Bronchi of Immunized Guinea Pigs 10.1159/000236282 1992
The immunological component of the cellular inflammatory infiltrate in bronchiectasis. 1989
Immunopathology of Experimental Bronchiectasis 10.1165/ajrcmb/1.4.297 1989
Estudo comparativo entre espirógrafo de campânula e um novo espirógrafo de fole 1987
Condutas na hemoptise 1985
Supurações broncopulmonares 1985
Intradermal BCG vaccination complications- Analysis of 51 cases 10.1016/0041-3879(83)90046-6 1983
Causas de morte na asma brônquica 1977
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
The role of BCG vaccine on airway and lung parenchima remodeling in a murine model of chronic allergic inflammation 2010
Case report: intrabronchial instillation of bone marrow derived mononuclear cells in silicotic patients 2010
Patterns of C-Reactive Protein Response to Antibiotic Therapy in Severe Community-Acquired Pneumonia Patients: A Cohort Study 2009
Medical Students at Risk for Nosocomial Tuberculosis Infection 2009
Artificial Neural Networks (ANN) To Predict Pulmonary Tuberculosis Diagnosis in Hospitals in Rio De Janeiro, Brazil 2009
[Poster Board #E15] Novel Tests in Parallel for Diagnosing Tuberculous Pleuritis 2009
The importance of frequency and plateau pressure during sigh recruitment manoever 2008
Impact f smoke inhalation injury, age and body surface area burned in patients with severe facial burns 2008
Computational analysis of the M. tuberculosis International Spolygotyping Database suggests that certain spoligopatterns may be derived from mixed infections 2008
Molecular Characterization of Interleukin-10 Proximal Promoter Region in Brazilian Subjects 2007
Molecular Analysis of Promoter Region of IFN-g coding gene in Brazilian Subjects with tuberculosis 2007
Is the severity pf tuberculosis different when patients are infected by strains of M. tuberculosis belonging to diverse spoligotyping families? 2007
CXCR3 and CCR5 chemokines in the induced sputum of patients with COPD 2007
Infection with multiple M. tuberculosis strains could lead to a false interpretation of the genotyping methods 2007
Genetic susceptibility to TB M. tuberculosis in Brazilian subjects: the possible role of Arg753Gln polymorphism in the human Toll-like Receptor 2 gene 2007
Increased levels of sputum IL-10 at the end of anti-tuberculosis (TB) chemotherapy is a marker for relapse 2007
Bronchial epithelium desquamation is na early prognostic sign of fatal outcome in severe facial burns 2007
. Immunologic abnormalities in young children with prior pulmonary and miliary/ meningeal tuberculosis 2006
Analysis of immunomodulatory molecules in lung cells of tuberculosis patients before and after chemotherapy by RT-PCR 2006
. Influence of variants alleles of mannose binding lectin (MBL) in the susceptibility to Mycobacterium tuberculosis infection 2006
Expression of costimulatory molecules on active tuberculosis (TB). 2006
. Is induced sputum a safe method to be used in COPD patients? 2006
TLR-4 expression after in vitro LPS stimulation of sputum cells from severe asthmatics does not change despite increases in CD14 expression 2006
PAF-aceylhydrolase activity in ventilator-associated pneumonia 2006
Pro-inflammatory cytokines fail to predict progrnosis in in ventilator-associated pneumonia 2006
Role of regulatory cytokines and inducible nitric oxide synthase (NOS) in active tuberculosis 2005
M. tuberculosis strains harboring a novel large chromossomal deletio (RDrio) are infectious, transmissible and the predominant cause of tuberculosis in Rio de Janeiro, Brazil 2005
Cytokine expression in the lungs of tuberculous patients before and after standard chemotherapy 2005
In vitro LPS stimulation of sputum cells from severe asthmatics increases CD14 expression 2005
Quantitative analysis of small airway muscle fibers in COPD, smoking, and non-smoking subjects 2005
Quantitative analysis of CD4+, CD8+, CD4+/CD8+ small airways in COPD, smoking, and non-smoking subjects 2005
Assessment of airway inflammationg using induced sputum in COPD, smoking, and non-smoking subjects 2005
Lung Tissue Mechanics and Extracellular Matrix Remodeling in a Murine Model of Chronic Asthma Am 2004
PCR-Based Genotypic Evaluation of M. tuberculosis Isolates from Rio de Janeiro, Brazil 2004
Cytokine Message in the Lungs of Tuberculosis Patients before and after Chemotherapy 2004
Quantitative Analysis of Elastic Fibers in COPD, Smoking, and Non-Smoking Subjects. 2004
Immunomodulatory cytokines in the pathogenesis of tuberculosis 2003
Extended freeze dried Mycobacterium bovis BCG reduce metaplasia, bronchial hyperreactivity and dendritic cell recruitment to the lungs of allergic mice 2003
. IgA and IgG immune response against the antigen P-90 in pulmonary tuberculosis patients 2003
Cervical immunity response induced by HPV and the influence of HIV-1 co-infection. 2002
BCG vaccination results in early recruitment of dendritic cells and upregulation of co-stimulatory molecules in mice with high TH2 background 2001
Non-smoking quarry mine workers exhibit signs of chronic bronchitis independently of the degree of exposure to silica dust 2001
Role of Transforming Growth Factor (TGF)-b receptors in tuberculous limphadenitis in HIV-infected or not patients 2000
Effects of BCG vaccination on the development of allergic inflammation and bronchial hyper-responsiveness (BHR) in newborn hyper-IgE BP2 mice 2000
Failure of granulocyte depletion to suppress mucin production in a murine model of allergy 2000
Inducible Nitric Oxide Synthase (Nos2) Expression By Sputum Inflammatory Cells Of Asthmatics: Modulation By Beclomethasone Dipropionate. 1999
Evaluation Of Bronchial Inflamation In Quarry Mine Workers In Rio de Janeiro By Induced Sputum 1999
Modulation Of Eosinophillic Bronchitis In Asthmatics By Inhaled Beclomethasone Dipropionate (Bdp) Is Accompanied By Increased Neutrophilia 1999
Levels Of Cytokines And Reactive Nitrogen Intermediates In Tuberculous Pleural Effusion 1999
Granuloma Formation Defect In Lymph Node Of Hiv-1 Tuberculosis Patients 1998
Phenotype Of Alveolar Mononuclear Phagocytes From Hiv-1 Infected Patients With Active Tuberculosis 1998
Transforming Growth Factor (Tgf)-B Ligand And Receptoras In Pulmonary Tuberculosis. 1998
Tuberculosis Conversion Among Health Care Workers In A General Hspital Of Rio de Janeiro, Brazil. Final Results. 1998
Increased Expression Of Fas And Fas-Ligand In The Bronchial Epithelium From Asthmatics 1997
Tuberculosis Infectivity Among Close Contacts Of Pulmonary Tuberculosis Patients In Rio de Janeiro, Brazil 1997
The Usefulness Of Induced Sputum (Is) For Diagnosis Of Pulmonary Tuberculosis (Pt) In Aids Reference Center, In Rio de Janeiro (Rj), Brazil: Preliminary Results. 1997
Increased Tumor Factor (Tnf)- A Levels In Bronchoalveolar Lavage Fluid In Patients With Tuberculosis And Hiv-1 Infection. 1997
Expression Of Hla-Dr By Alveolar Macrophages From Affected Areas Of Tuberculosis Patients Co-Infected With Hiv 1997
Cytokine Expression In Lung Cells From Patients With Tuberculosis And Aids. 1997
Inducible Nitric Oxide Synthase And Cytokine Expression In Lung Cells From Patients With Tuberculosis 1997
The Role Of Neutrophils And Eosinophils In Human Bronchiectasis 1997
Fk506 Down-Regulates A-4 Integrin Expression In The Lungs Of Sensitized Guinea Pigs 1996
Effect Of Salmeterol An Antigen-Induced T-Lymphocyte And Eosinophil Infiltration Into The Airways Of Sensitised Guinea Pigs. 1996
Effects Of Capsaicin Treatment On Chronic Airway Inflammation Induced By Repeated Antigen Exposure In Guinea Pigs 1996
Drug Resistant Tuberculosis In A General Hospital - Aids Reference Center, In Aids Reference Center, In Rio de Janeiro, Brazil 1996
Effect Of Salmeterol An Antigen-Induced T-Lymphocyte And Eosinophil Infiltration Into The Airways Of Sensitised Guinea Pigs. 1996
Fk506 Down-Regulates A-4 Integrin Expression In The Lungs Of Sensitized Guinea Pigs. 1996
Fk506 Down-Regulates A-4 Integrin Expression On Eosinophils In Sensitized Guinea Pigs. 1996
Tuberculin Skin Test Conversion Among Close Contacts Of Pulmonary Tuberculosis Patients, Infected Or Not By Hiv 1996
. Kinetics Of Antigen-Induced Changes In The Airways Of Aerosol Sensitized Guinea Pigs. 1995
Markers Of Airway Inflammation In Guinea Pig Immunized With Toluene Diisocyanate 1995
Neurokinin Depletion Attenuates Inflammatory Pulmonary Response To Repeated Antigen Exposures In Guinea Pigs 1995
Phenotype Of Alveolar Macrophages In The Bronchoalveolar Lavage Fluid Of Tuberculosis Patients 1995
A Subpopulation Of Th0/Th2 T-Lymphocytes Is Expanded In The Bronchoalveolar Lavage Fluid Of Tuberculosis Patients. 1995
Kinetics Of Vla-4 Changes In The Airways Of Aerosol Sensitized Guinea Pigs 1995
Modulation Of Bronchial Inflammation In Sensitized Guinea Pigs By Intra-Tracheally Administered Fluticasone Propionate And Dexametasone. 1995
Effect Of Salmeterol On Antigen-Induced T-Lymphocyte And Eosinophil Infiltration Into The Airways Of Sensitised Guinea Pigs. 1995
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