Ana Carolina de Siqueira Couto de Oliveira

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biofísica/I Biof

ORCID:

não disponível no Lattes


Formação:

  • Monash University

    | Pós-Doutorado | 2014 - 2014

  • Instituto de Microbiologia Prof. Paulo de Góes - UFRJ

    | Pós-Doutorado | 2007 - 2008

  • Universidade Federal do Rio de Janeiro

    Ciências (Microbiologia) | Doutorado | 2003 - 2007

  • Universidade Federal do Rio de Janeiro

    Ciências (Microbiologia) | Mestrado | 2001 - 2003

  • Universidade Federal do Rio de Janeiro

    Bacharelado Em Microbiologia e Imunologia | Graduação | 1997 - 2000
Laboratórios:
Nuvens de Palavras:
Artigos:

(96.43% artigos com DOI)

Titulo DOI Ano
Genetic Ablation and Pharmacological Blockade of Bradykinin B1 Receptor Unveiled a Detrimental Role for the Kinin System in Chagas Disease Cardiomyopathy 10.3390/jcm12082888 2023
High mobility group box 1, ATP , lipid mediators, and tissue factor are elevated in COVID -19 patients: HMGB1 as a biomarker of worst prognosis 10.1111/cts.13475 2023
Cytotoxic CD4 + T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts 10.7554/eLife.74636. 2022
Characterization of the oxidative stress response regulatory network in Bacteroides fragilis: An interaction between BmoR and OxyR regulons promotes abscess formation in a model of intra-abdominal infection 10.1016/j.anaerobe.2022.102668 2022
Dietary Fiber Drives IL-1β-Dependent Peritonitis Induced by via Activation of the NLRP3 Inflammasome 10.4049/jimmunol.2000078 2021
Recombinant human DNase I for the treatment of cancer-associated thrombosis: A pre-clinical study 10.1016/j.thromres.2021.04.028 2021
Surface megalin expression is a target to the inhibitory effect of bradykinin on the renal albumin endocytosis 10.1016/j.peptides.2021.170646 2021
IL-18R signaling is required for γδ T cell response and confers resistance to Trypanossoma cruzi infection 10.1002/JLB.4MA0420-568R 2020
CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection 10.1038/s41598-019-45138-7 2019
Primary evidences of the mechanisms of action of HIV aspartyl peptidase inhibitors on Trypanosoma cruzi trypomastigote forms 10.1016/j.ijantimicag.2018.03.021 2018
Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression 10.3389/fimmu.2018.01173 2018
Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes 10.1038/ni.3713 2017
Mast Cell Coupling to the Kallikrein-Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease 10.3389/fimmu.2017.00840 2017
Crucial role for T cell-intrinsic IL-18R-MyD88 signaling in cognate immune response to intracellular parasite infection 10.7554/elife.30883 2017
The interplay between microbiota and inflammation: lessons from peritonitis and sepsis 10.1038/cti.2016.32 2016
G Protein-Coupled Receptor 43 Modulates Neutrophil Recruitment during Acute Inflammation 10.1371/journal.pone.0163750 2016
A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection 10.1177/0022034515593465 2015
The Calpain Inhibitor MDL28170 Induces the Expression of Apoptotic Markers in Leishmania amazonensis Promastigotes 10.1371/journal.pone.0087659 2014
Porphyromonas gingivalis Fimbriae Dampen P2X7-Dependent Interleukin-1- Secretion 10.1159/000363338 2014
The kallikrein-kinin system in experimental Chagas disease: a paradigm to investigate the impact of inflammatory edema on GPCR-mediated pathways of host cell invasion by Trypanosoma cruzi. 10.3389/fimmu.2012.00396 2013
Inactivation of a fibronectin-binding TonB-dependent protein increases adhesion properties of Bacteroides fragilis 10.1099/jmm.0.054692-0 2013
The Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development 10.1155/2012/507874 2012
Cruzipain Promotes Trypanosoma cruzi Adhesion to Rhodnius prolixus Midgut 10.1371/journal.pntd.0001958 2012
Miltefosine induces programmed cell death in Leishmania amazonensis promastigotes 10.1590/s0074-02762011000400021 2011
Impaired Innate Immunity in Tlr4−/− Mice but Preserved CD8+ T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice 10.1371/journal.ppat.1000870 2010
Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi 10.1189/jlb.0706478 2007
Expression of Functional TLR4 Confers Proinflammatory Responsiveness to Trypanosoma cruzi Glycoinositolphospholipids and Higher Resistance to Infection with T. cruzi 10.4049/jimmunol.173.9.5688 2004
Costimulatory Action Of Glycoinositolphospholipids From Trypanosoma Cruzi: Increased Interleukin 2 (IL-2) Secretion And Induction Of Nuclear Translocation Of The Nuclear Factor Of Activated T Cells 1 1999
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Characterization of gd T cells in acute infection with the Y strain of Trypanosoma cruzi 2016
Mechanisms underlying activation of NLRP3 inflammasome during murine peritonitis 2016
CD4+ T cells specifically differentiate into cytotoxic T lymphocytes upon experimental Trypanosoma cruzi infection 2016
HTLV-1 induction of inflammasome activation 2016
Dietary fibre contributes to inflammasome activation and peritonitis development in murine model 2015
NLRP3 INFLAMMASOME IS ESSENTIAL TO PERITONITIS DEVELOPMENT: THE PROINFLAMMATORY ROLE OF PARTICULATE DIETARY FIBRE 2015
Endothelial barrier breakdown in experimental Chagas disease: activation of the kallikrein-kinin system couples inflammatory edema to heart parasitism and associated pathology 2015
IL1R1-/- and IL18RA-/- mice are highly susceptible to infection with Trypanosoma cruzi 2014
NLRP3 activation by a particulate matter from intestinal content is essential to peritonitis development 2014
ROLE OF THE MICROCIRCULATION IN THE PATHOGENESIS OF CHAGAS DISEASE: EVIDENCES LINKING ACTIVATION OF BRADYKININ B1 RECEPTORS TO INCREASED INTRACARDIAC PARASITISM AND ADVERSE PATHOGENIC OUTCOME IN CHRONIC INFECTION 2014
The role of inflammasome and IL-1b in intra-abdominal abscess development induced by commensal bacteria Bacteroides fragilis 2013
The axis ASC-caspase-1-IL-1 is decisive for the abdominal abscess induced by Bacteroides fragilis and sterile cecal contents 2013
Mice deficient in Bradykinin B1 receptor display a cardioprotective phenotype characterized by reduced intracardiac parasitism and impaired recruitment of proinflammatory subsets of monocytes 2013
Intracardiac edema propagated via the mast cell-kallikrein-kinin system fuels Trypanosoma cruzi infection, contributing to chronic myocarditis and heart fibrosis. 2013
Crucial role of IL-18R1 signaling in Th1 cell differentiation in mice infected with Trypanosoma cruzi. 2013
EXPLORING THE INFLAMMATORY ROLE OF THE MAST CELL/KALLIKREIN-KININ CELL PATHWAY IN THE MODULATION OF T CELL RESPONSES AGAINST Trypanosoma cruzi 2012
CD8+ T cell migration to the myocardium is enhanced in MyD88-deficient mice infected with Trypanosoma cruzi 2012
Inflammasome activation and IL-1 contribute to intra-abdominal abscess development induced by commensal bacteria Bacteroides fragilis 2012
EXPLORING THE INFLAMMATORY ROLE OF THE MAST CELL/KALLIKREIN-KININ CELL PATHWAY IN THE MODULATION OF T CELL RESPONSES AGAINST Trypanosoma cruzi 2012
Critical role of MyD88 expression in Th1 cells during infection with Trypanosoma cruzi 2012
INFECTION WITH TRYPANOSOMA CRUZI MODULATES CD39 EXPRESSION AND ECTONUCLEOTIDASE ACTIVITY ON MURINE MACROPHAGES 2011
TRYPANOSOMA CRUZI INVADES HOST CELLS THROUGH THE ACTIVATION OF ENDOTHELIN AND BRADYKININ RECEPTORS: A CONVERGING PATHWAY LEADING TO CHAGASIC VASCULOPATHY 2011
TLR signaling and Trypanosoma cruzi infection modulate CD39 expression and nucleotidase activity in murine macrophages 2011
Impaired innate immunity but preserved CD8+ T cell responses against Trypanosoma cruzi in TLR2-, TLR4-, TLR9- or MyD88-deficient mice 2010
Impaired innate immunity in TLR4-/- mice but preserved CD8+ T cell responses against Trypanosoma cruzi in TLR4-, TLR2-, TLR9- or Myd88- deficient mice 2010
Involvement of Toll-like receptors in activation of neutrophils leading to the release of NETs 2010
Toll-like Receptor Activation Induces Nucleoside Triphosphate Diphosphohydrolase 1 (NTPDase1)/CD39 Modulation in Murine Macrophages 2010
PRESERVATION OF CD8 T CELL EFFECTOR RESPONSES DURING INFECTION WITH TRYPANOSOMA CRUZI IN MICE LACKING MYD88 OR TOLL-LIKE RECEPTORS. 2009
THE PRO-INFLAMMATORY PRIMING INDUCED BY PLASMODIUM CHABAUDI INFECTION INDUCES ASC AND CASPASE-1 ACTIVATION AND DELETERIOUS IL-1 BETA RESPONSE DURING MALARIA 2009
Tha effects of MDL 28170 in Leishmania amazonensis infection in vitro 2008
TLR-4dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipids (GIPL) from Trypanosoma cruzi 2007
Frequency of IFN-gama secreting cells and specific in vivo lytic activity in TLR2-deficient mice infected with Trypansoma cruzi 2006
Leishmanicidal response triggered in murine macrophages by toll-like receptors (TLR) 2006
OUAbain increases response to LPS. 2005
Expression of functional TLR4 confers higher resistance to infection with Trypanosoma cruzi 2004
TLR4-dependent proinflammatory activity induced in vivo and in vitro by glycoinositolphospholipids(GIPLs) from Trypanosoma cruzi 2003
Nuclear factor activation induced by glycoinositolphospholipid (GIPL) from T. cruzi on murine T cells 2002
Phosphorylation of c-Jun is induced in murine T lymphocytes by glycoinositolphospholipids (GIPLs) from Trypanosoma cruzi 2001
Efeitos do glicoinositolfosfolipídeo (GIPL) isolado de Trypanosoma cruzi na ativação do fator de transcrição AP-1 em linfócitos T 2000
Efeitos do glicoinositolfosfolipídeo isolado de Trypanosoma cruzi sobre a ativação do fator de transcrição AP-1 2000
A porção lipídica do glicoinositolfosfolipídeo (GIPL) isolado de Trypanosoma cruzi é responsável pelo efeito co-estimulatório em linfócitos T murinos 1999
Glycoinositolphospholipid (Gipl) Isolated From T. Cruzi Induces Nuclear Translocation Of Nfat1 And Increases Il-2 Secretion By A Murine T-Cell Hybridoma 1998
Nuclear Translocation Of Nfat1, Cytosolic Calcium And Il-2 Secretion Increase Induced In Murine T Cells By Glycoinositolphospholipids (Gipls) Isolated From Trypanosoma Cruzi 1998
Glicoinositolfosfolipídeo (Gipl) Isolado de T. Cruzi Induz A Translocação Nuclear do Nfat1 e Causa Aumento da Secreção de Il2 Por Hibridoma T 1998
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