André Macedo Vale

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biologia Molecular e Estrutural/Biof

ORCID:

https://orcid.org/0000-0001-7501-2370


Formação:

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2012 - 2013

  • University of Alabama at Birmingham

    | Pós-Doutorado | 2009 - 2012

  • Universidade Federal do Rio de Janeiro

    Ciências (Microbiologia) | Doutorado | 2005 - 2009

  • Universidade Federal de Minas Gerais

    Parasitologia | Mestrado | 2003 - 2005

  • Universidade Federal de Minas Gerais

    Farmácia | Graduação | 1999 - 2002

  • Universidade Federal de Minas Gerais

    Patologia Cínica | Ensino Profissional de nível técnico | 1994 - 1996
Laboratórios:
Nuvens de Palavras:
Artigos:

(95.56% artigos com DOI)

Titulo DOI Ano
Long-term recruitment of peripheral immune cells to brain scars after a neonatal insult 10.1002/glia.24490 2024
Oligosymptomatic long-term carriers of SARS-CoV-2 display impaired innate resistance but increased high-affinity anti-spike antibodies 10.1016/j.isci.2023.107219 2023
High mobility group box 1, ATP , lipid mediators, and tissue factor are elevated in COVID -19 patients: HMGB1 as a biomarker of worst prognosis 10.1111/cts.13475 2023
Mature Naive B Cells Regulate the Outcome of Murine Acute Graft-versus-Host Disease in an IL-10-Independent Manner 10.1016/j.jtct.2022.01.004 2022
Plasma and memory antibody responses to Gamma SARS-CoV-2 provide limited cross-protection to other variants 10.1084/jem.20220367 2022
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum 10.3389/fimmu.2022.884760 2022
From a recombinant key antigen to an accurate, affordable serological test: lessons learnt from COVID-19 for future pandemics 10.1016/j.bej.2022.108537 2022
The major role of junctional diversity in the horse antibody repertoire 10.1016/j.molimm.2022.09.011 2022
COVID-19 diverse outcomes: Aggravated reinfection, type I interferons and antibodies 10.1016/j.mehy.2022.110943 2022
Humoral response in Leishmaniasis 10.3389/fcimb.2022.1063291 2022
Effect of Convalescent Plasma in Critically Ill Patients With COVID-19: An Observational Study 10.3389/fmed.2021.630982 2021
The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self 10.1084/jem.20210580 2021
Time-dependent decay of detectable antibodies against SARS-CoV-2: a comparison of ELISA with two batches of a lateral-flow test 10.1016/j.bjid.2021.101601 2021
Genetic Evidence and Host Immune Response in Persons Reinfected with SARS-CoV-2, Brazil 10.3201/eid2705.204912 2021
Fc Receptor-Like 6 (FCRL6) Discloses Progenitor B Cell Heterogeneity That Correlates With Pre-BCR Dependent and Independent Pathways of Natural Antibody Selection 10.3389/fimmu.2020.00082 2020
B-1 lymphocytes are able to produce IL-10, but is not pathogenic during Leishmania (Leishmania) amazonensis infection 10.1016/j.imbio.2019.10.006 2020
Protective effect of fungal extracellular vesicles against murine candidiasis. 10.1111/cmi.13238 2020
Dietary Vitamin D3 Deficiency Increases Resistance to Leishmania (Leishmania) amazonensis Infection in Mice 10.3389/fcimb.2019.00088 2019
The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy 10.1371/journal.pntd.0007146 2019
CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection 10.1038/s41598-019-45138-7 2019
Probiotic treatment during neonatal age provides optimal protection against experimental asthma through the modulation of microbiota and T cells 10.1093/intimm/dxy011 2018
The sequences encoded by immunoglobulin diversity (D ) gene segments play key roles in controlling B-cell development, antigen-binding site diversity, and antibody production 10.1111/imr.12669 2018
Critical role of CD4+ T cells and IFNγ signaling in antibody-mediated resistance to Zika virus infection 10.1038/s41467-018-05519-4 2018
Immunomodulating role of IL-10-Producing B cells in Leishmania amazonensis infection 10.1016/j.cellimm.2018.08.014 2018
TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells 10.3389/fimmu.2018.02281 2018
The Global Self-Reactivity Profile of the Natural Antibody Repertoire Is Largely Independent of Germline DH Sequence 10.3389/fimmu.2016.00296 2016
Expression of leukosialin (CD43) defines a major intrahepatic T cell subset associated with protective responses in visceral leishmaniasis 10.1186/s13071-015-0721-9 2015
Violation of an Evolutionarily Conserved Immunoglobulin Diversity Gene Sequence Preference Promotes Production of dsDNA-Specific IgG Antibodies 10.1371/journal.pone.0118171 2015
The role of evolutionarily conserved germ-line D H sequence in B-1 cell development and natural antibody production 10.1111/nyas.12808 2015
The link between antibodies to OxLDL and natural protection against pneumococci depends on DH gene conservation 10.1084/jem.20121861 2013
Linkage of Natural Antibody Immunologic Homeostasis to Anticipatory Protection against a Common Pathogen Requires Natural Selection of Immunoglobulin Diversity Gene Segment Sequence 2013
A rapid and quantitative method for the evaluation of V gene usage, specificities and the clonal size of B cell repertoires 10.1016/j.jim.2011.12.005 2012
Absence of N addition facilitates B cell development, but impairs immune responses 10.1007/s00251-011-0543-7 2011
Long-Term Maintenance of Polysaccharide-Specific Antibodies by IgM-Secreting Cells 10.4049/jimmunol.1100783 2011
Genetic control of the B cell response to LPS: opposing effects in peritoneal versus splenic B cell populations 10.1007/s00251-009-0404-9 2010
Clinical consequences of defects in B-cell development 10.1016/j.jaci.2010.02.018 2010
DH and JH usage in murine fetal liver mirrors that of human fetal liver 10.1007/s00251-010-0469-5 2010
The Peritoneal Cavity B-2 Antibody Repertoire Appears To Reflect Many of the Same Selective Pressures That Shape the B-1a and B-1b Repertoires 10.4049/jimmunol.1001423 2010
The CDR-H3 Repertoire from TdT-Deficient Adult Bone Marrow Is a Close, but Not Exact, Homologue of the CDR-H3 Repertoire from Perinatal Liver 10.4049/jimmunol.1001419 2010
Identification of Highly Specific and Cross-Reactive Antigens of Leishmania Species by Antibodies from Leishmania (Leishmania) chagasi Naturally Infected Dogs 10.1111/j.1863-2378.2008.01183.x 2009
Antigenicity of a whole parasite vaccine as promising candidate against canine leishmaniasis 10.1016/j.rvsc.2007.09.008 2008
Evaluation of an immunochemotherapeutic protocol constituted of N-methyl meglumine antimoniate (Glucantime((R))) and the recombinant Leish-110f((R))+MPL-SE((R)) vaccine to treat canine visceral leishmaniasis 10.1016/j.vaccine.2008.01.026 2008
Isotype patterns of immunoglobulins: hallmarks for clinical and parasitic status in brazilian dogs naturally infected by Leishmania (Leishmania) chagasi 10.1016/j.vetimm.2006.02.001 2006
Flow cytometric assay in peripheral blood of dogs reference values for leukocytes from Brazilian Beagles 2005
Immunogenicity in dogs of three recombinant antigens (TSA, LeIF and LmSTI1) potential vaccine candidates for canine visceral leishmaniasis 10.1051/vetres:2005033 2005
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Characterization of the immunoglobulin repertoire secreted by B cells responsive to different TLR agonists 2016
Dynamics of B cell subpopulations and autoantibody production during experimental ZIKV infection 2016
Characterization of the Repertoire of Natural Antibodies anti-HSC70 2015
Maintenance of B cells with hydrophobic CDR-H3 intervals whitin the peritoneal cavity 2015
Natural antibodies anti-HSC70 repertoire characterization 2014
Role of Db Germline Sequence on Constraining TCR CDRb3 Diversity 2012
Immune Defense Against Streptococcus pneumoniae is Influenced by Germline Immunoglobulin DH Amino Acid Sequence 2011
Immune Defense Against Streptococcus pneumoniae is Influenced by Germline Immunoglobulin DH Amino Acid Sequence 2011
The Role of Immunoglobulin DH Amino Acid Sequence in Regulatiing Immune Defence Against Streptococcus pneumoniae 2011
Production of Natural Autoantibodies That Provide Anticipatory Protection Against a Common Microbe Quantitatively Depends on Evolutionarily Conserved DH Sequence 2011
Evidence that self antigen specificity is the ultimate driver of the composition of the natural antibody repertoire 2010
Both the B-1 and B-2 Peritoneal Cavity Antibody CDR-H3 Repertoires Appear to be Influenced by the Same Selective Pressures 2010
Fast and Quantitative Method for the Isolation, Production and Sequencing of Immunoglobulin from Fresh Single Cells 2010
Impact of Genetic Restriction of VDJ Rearrangement on the Natural Antibody Repertoire 2010
Genetic control of B cell response to LPS: Differential effects in distinct B cell populations. 2009
Fast and Qauntitative Method for the Description of Immunoglobulin Repertoires 2009
Impact of genetic restriction of the VDJ rearrangement on the natural antibody repertoire 2007
Analysis of serum IgM repertoire of mice with genetic restriction of VDJ rearrangement 2006
Efeito Repelente e Ação Adulticida de uma Formulação Tópica Contendo Imidacloprida 10% + Permetrina 50% Contra Fflebotomíneos (Lutzomyia longipalpis) em cães 2005
Identificação de Antígenos de Reatividade Cruzada em Diferentes Espécies de Leishmania do Novo Mundo 2005
Ensaio Clínico para Avaliação do Protocolo de Imunoquimioterapia com Antimoniato de N-Metil Meglumina (Glucantime®), Associado a Vacina Recombinante (Leish-111f® MPL-SE®) no Tratamento de Cães Sintomáticos Naturalmente Infectados com Leishmania chagasi? 2004
Estudo Comparado no Diagnóstico da Leishmaniose Visceral Canina 2004
Controle da Leishmaniose Visceral na Cidade de Janaúba, Minas Gerais, Brasil. Perspectivas e Resultados Preliminares 2004
Assesment of the Potency and Stability of Different Cutaneous Leishmaniasis Vaccine Formulations Using Immunological and Biochemical Parameters 2004
Controle de leishmaniose visceral canina no período de 1998 a 2003 na cidade de Porteirinha, Norte do Estado de Minas Gerais, Brasil 2004
Caracterization of clinical parameters of visceral leishmaniasis in dogs naturally infected with L. (L.) chagasi 2003
The clinical spectrum in canine visceral leishmaniasis and the changes in the isotypes patterns of immunoglobulins 2003
Isotypes Patterns of Immunoglobulins: Indicators of the Clinicl Status in Canine Visceral Leismaniasis 2002
Serological and Hematological Changes in Canine Visceral Leishmaniasis 2002
Avaliação da Imunogenicidade de Antígenos Recombinantes para Leishmaniose Visceral Canina 2002
Padrões de Classes e Subclasse de Imunoglobulinas Associados à Clínica da Leishmaniose Visceral Canina 2002
Evaluation of Immunogenicity of Recombinant Antigens for Canine Visceral Leishmaniasis 2002
IgG2 and IgE Leishmania-Specific Antibodies: Marckers of Severe Disease in Visceral Canine Leishmaniasis 2001
Cellular and Humoral Immune Response in Dogs Immunized with Anti-Canine Visceral Leishmaniasis Vaccine 2001
A Evolução Clínica da Leishmaniose Visceral e a Resposta Imune de Cães Naturalmente Infectados 2000
Novo Foco de Leishmaniose no Norte de Minas Gerais, Brasil 2000
O Impacto do Parasitismo no Baço, Pele e Medula Óssea em Cães com Diferentes Formas Clínicas da Leishmaniose Visceral 2000
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