Alexandre dos Santos Pyrrho

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Farmácia

Departamento:

Departamento de Análise Clínica e Toxicologica

ORCID:

https://orcid.org/0000-0003-0847-1301


Formação:
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1995 - 2001
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Mestrado | 1993 - 1995
  • Universidade Federal Fluminense

    Medicina Veterinária | Graduação | 1986 - 1991
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas | Graduação | 1983 - 1986
Laboratórios:
Nuvens de Palavras:
Artigos:

(59.09% artigos com DOI)

Titulo DOI Ano
Evaluation of Silybin Nanoparticles against Liver Damage in Murine Schistosomiasis mansoni Infection 10.3390/pharmaceutics16050618 2024
Evaluation of Hyperthermic Potential and Acute Toxicity of PLGA-PEG/Magnetite Microspheres Loaded with Oxaliplatin Using Mice as a Test System 10.1002/mren.202300005 2023
Environmental and Economic Values of salt tolerance. Euphorbia tirucalli: Phytoremediation potentia 10.22161/ijaers.106.5 2023
Constructed Wetlands: Technology for Removing Drug Concentration from Water 10.22161/ijaers.104.13 2023
Deep convolutional neural network applied to _Trypanosoma cruzi_ detection in blood samples 10.1504/ijbic.2022.120749 2022
Influence of different sources of contamination on the microbiological quality of lettuce in the Teresópolis region, RJ, Brazil 10.1590/s1413-41522020144815 2020
Interaction and involvement of cellular adhesion molecules in the pathogenesis of Schistosomiasis mansoni 10.1016/j.imlet.2018.11.011 2019
Toxicological and anatomical study of vegetative organs of Anthurium maricense Nadruz and Mayo (Araceae) 10.18406/2316-1817v11n220191289 2019
Meglumine-based supra-amphiphile self-assembled in water as a skin drug delivery system: Influence of unfrozen bound water in the system bioadhesiveness 10.1016/j.colsurfb.2019.110523 2019
Non-invasive methods for diagnosis of liver fibrosis: a systematic approach 10.21877/2448-3877.201900852 2019
Determination of toxicity and chromatographic analysis of spilanthol content in in vitro culture of Spilanthes oleracea Jacq. 10.5897/ajb2017.16313 2018
Emerging Role of HMGB1 in the Pathogenesis of Schistosomiasis Liver Fibrosis 10.3389/fimmu.2018.01979 2018
Homeopathic medicines cause Th1 predominance and induce spleen and megakaryocytes changes in BALB/c mice infected with Leishmania infantum 10.1016/j.cyto.2017.02.010 2017
In vitro and in vivo Evaluation of DMSO and Azone as Penetration Enhancers for Cutaneous Application of Celecoxib 10.2174/1567201814666170125120331 2017
Infection by Schistosoma mansoni during pregnancy: Effects on offspring immunity 10.1016/j.lfs.2017.07.021 2017
Promotion of cutaneous penetration of nifedipine for nanoemulsion 10.1590/s2175-97902017000215249 2017
PAMAM dendrimer hydrogel film-biocompatible material to an efficient dermal delivery of drugs 10.1007/s11051-017-3965-9 2017
Biodistribution of Praziquantel (PZQ) Nanoemulsion (NE) in Healthy Wistar Rats: Evaluation of Biological Behavior 10.1166/jbns.2016.1403 2016
Evaluation of Leishmania infantum 30x biotherapy effects in the prevention and treatment of visceral leishmaniasis: in vivo and in vitro studies 2016
Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response 10.1371/journal.pone.0139805 2015
Silymarin reduces pro-fibrogenic cytokines and reverses hepatic fibrosis in chronic murine schistosomiasis 10.1128/aac.01936-13 2014
Abate Clandestino: uma Questão a Ser Enfrentada 2013
Layered double hydroxides intercalated with anionic surfactants/benzophenone as potential materials for sunscreens 10.1016/j.jcis.2013.01.059 2013
Surtos de Toxinfecções Alimentares Ocorridos em Municípios de Minas Gerais 2013
In vitro and in vivo influence of penetration enhancers in the topical application of celecoxib 10.3109/03639045.2013.809731 2013
Risco de Transmissão de Patógenos pelo Uso do Gelo 2012
Benefício do Treinamento de Manipuladores de Alimentos na Higienização de Hortaliças 2012
In vitro and in vivo studies into the biological activities of 1,10-phenanthroline, 1,10-phenanthroline-5,6-dione and its copper(ii) and silver(i) complexes 10.1039/c2tx00010e 2012
Surtos de Doenças Transmitidas por Alimentos Associados ao Consumo de Sorvete 2011
Silymarin treatment reduces granuloma and hepatic fibrosis in experimental schistosomiasis 10.1007/s00436-010-2014-8 2010
Endoparasitos em Muriquis-do-Norte, Brachyteles hypoxanthus, Isolados em Pequeno Fragmento de Mata Atlântica 2009
CCL2/MCP-1 controls parasite burden, cell infiltration, and mononuclear activation during acute Trypanosoma cruzi infection 10.1189/jlb.0309187 2009
Macrophage migration inhibitory factor is critical to interleukin-5-driven eosinophilopoiesis and tissue eosinophilia triggered by Schistosoma mansoni infection 10.1096/fj.08-124248 2009
Chronic toxicological effects of high diluted solutions of Aveloz (Euphorbia tirucalli L.) on healthy mice: a preliminary study 2008
Unraveling the lethal synergism between Trypanosoma cruzi infection and LPS: a role for increased macrophage reactivity 2007
Efeito de Diferentes Preparos Farmacotécnicos de Soluções Ultradiluídas de Euphorbia tirucalli (Aveloz) sobre a Variação de Leucócitos em Esfregaço 2006
Dexamethasone treatment improves morphological and hematological parameters in chronic experimental schistosomiasis 2004
Trypanosoma cruzi sensitizes mice to fulminant SEB-induced shock:overrelase of inflamatory cytokines and independence of Chagas'disease or TCR Vbeta-usage 2003
Balanced cytokine-producing pattern in mice immunized with an avirulent Trypanosoma cruzi 2003
Dexamethasone, a drug for attenuation of Schistosoma mansoni infection morbidity. 2002
Avaliação microbiológica de frutas e hortaliças frescas, servidas em restaurantes self-service privados, da Universidade Federal do Rio de Janeiro 2002
Trypanosoma cruzi: requirements for induction and maintenance of protective immunity conferred by immunization 2002
Antibody production in mice immunized with plasmid DNA encoding the colonization factor antigen I (CFA/I) of enterotoxigenic Escherichia coli. 1999
Trypanosoma cruzi: IgG1 and IgG2b are the main immunoglobulins produced by vaccinated mice 1998
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Effect of silymarin on Pdr5p activity from yeast plasma membrane 2011
In vitro and in vivo characterization of cutaneous delivery systems for antinflammatory celecoxib 2011
Effects of Silymarin on Experimental Schistosomiasis Murine 2010
Effects of Silymarin on Experimental Schistosomiasis Murine 2010
Effects of Silymarin on Experimental Schistosomiasis Murine 2010
9-EFFECT OF DIFFERENT PREPARATION FARMACOTECHNICS OF EXTREMELY-DILUTED SOLUTIONS OF Euphorbia tirucalli Lineu (AVELOZ) UPON LEUCOCITES VARIATION. 2006
MCP-1 controls the distribution composition and activation of mononuclear tissue infiltrates in acute Trypanosoma cruzi infection 2006
Unravelling the lethal synergism between Trypanosoma cruzi infection and LSP: a role for increased macrophage reactivity 2006
Chronic dexamethasone treatment results in alteration of cytokine production, granuloma size, and fibrosis in experimental Schistosoma mansoni infection. 2001
Trypanocidal activity of alkaloides purified from Uncaria guianensis 2000
Uso do extrato de Kalanchoe pinnata na proteção contra o choque anafilático em camundongos 2000
Perfil de Susceptibilidade aos antimicrobianos e marcadores de agressão da microbiota de frutas e hortaliças servidas em restaurantes do Rio de Janeiro 2000
Immunomodulation effects of pentoxifylline in Schistosomiasis mansoni 1999
Immunomodulation of collagen deposition in livers of Schistosomiasis infected mice by dexamethasone. 1999
Immunomodulatory effect of glucocorticoid on kidney of mice infected with Schistosoma mansoni 1999
Immunomodulatory effect of glucocorticoid on kidney of mice Schistosomiasis. 1999
Influência da pentoxifilina na hematopoiese murina normal e na esquistossomose mansônica crônica. 1999
Aspectos higiênicos sanitários de hortaliças e frutas comercializadas em dois restaurantes da cidade do Rio de Janeiro. 1999
Trypanosoma cruzi sensitizes mice to fulminant SEB-induced shock: hyperreactivity of Vbeta8 cells and independence of Chagas'disease or TCR Vbeta-usage. 1999
Anti-Trypanosoma cruzi vaccine: participation of humoral immunity and lymphocyte subsets in protection. 1998
Characterization of cytokine and antibody production in mice vaccinated against Trypanosoma cruzi. 1997
Trypanosoma cruzi: differences in antibodies production between infected and vaccinated mice 1996
T-cell repertoire changes in response to T. cruzi vaccination 1995
Expressão diferencial de isotipos de imunoglobulinas em animais infectados e vacinados contra Trypanosoma cruzi 1995
Trypanosoma cruzi: analysis of T cell subsets in vaccinated mice 1994
Immunoglobulins Isotypes In Trypanosoma cruzi Vaccinated Mice. 1994
Increase in CD8+ in Mice Vaccinated with a Non-infective Clone of Trypanosoma cruzi. 1993
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