Camilo Henrique da Silva Lima
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências Matemáticas e da Natureza
Unidade:
Instituto de Química
Departamento:
Departamento de Química Orgânica/IQ
Formação:
-
Universidade Federal Fluminense
| Pós-Doutorado | 2016 - 2018
-
Universidade Federal do Rio de Janeiro
Química | Doutorado | 2011 - 2015
-
Universidade Federal do Rio de Janeiro
Química | Mestrado | 2009 - 2011
-
Universidade Federal Fluminense
farmacia industrial | Graduação | 2003 - 2008
Laboratórios:
Nuvens de Palavras:
Artigos:
(98.33% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Exploring Urease Inhibition by Coumarin Derivatives through in silico and in vitro Methods | 10.21577/0103-5053.20230151 | 2024 |
| Molecular modelling studies and in vitro enzymatic assays identified A 4-(nitrobenzyl)guanidine derivative as inhibitor of SARS-CoV-2 Mpro | 10.1038/s41598-024-59292-0 | 2024 |
| In silico drug repurposing by combining machine learning classification model and molecular dynamics to identify a potential OGT inhibitor | 10.1080/07391102.2023.2199868 | 2024 |
| Putative Inhibitor of TcCYP51 from a Library of Approved Drugs: A Virtual Screening Study | 10.21577/0103-5053.20240064 | 2024 |
| Statine-based peptidomimetic compounds as inhibitors for SARS-CoV-2 main protease (SARS-CoV-2 Mpro) | 10.1038/s41598-024-59442-4 | 2024 |
| O-β-N-acetil-D-glicosaminiltransferase (OGT): Passado e Presente na Busca por Inibidores de um Interessante Alvo Terapêutico | 10.21577/1984-6835.20240027 | 2024 |
| Py-CoMFA, docking, and molecular dynamics simulations of Leishmania (L.) amazonensis arginase inhibitors | 10.1038/s41598-024-62520-2 | 2024 |
| In-vitro biological evaluation of 3,3-,5,5--tetramethoxy-biphenyl-4,4--diol and molecular docking studies on trypanothione reductase and Gp63 from Leishmania amazonensis demonstrated anti-leishmania potential | 10.1038/s41598-023-34124-9 | 2023 |
| -REAÇÃO NOBEL NA ORGEXP2-: DEMONSTRAÇÃO DE UMA REAÇÃO CLICK CHEMISTRY NO LABORATÓRIO DE QUÍMICA ORGÂNICA EXPERIMENTAL 2 | 10.22407/1984-5693.2023.v15.p.e20231503 | 2023 |
| Inclusion complex of O-allyl-lawsone with 2-hydroxypropyl-β-cyclodextrin: Preparation, physical characterization, antiparasitic and antifungal activity | 10.1007/s10863-023-09970-x | 2023 |
| Development, validation and analysis of a human profurin 3D model using comparative modeling and molecular dynamics simulations | 10.1080/07391102.2023.2231546 | 2023 |
| Molecular targets for chalcones in antileishmanial drug discovery | 10.2174/1389557523666230127125058 | 2023 |
| Molecular modeling of [VO(L1-4)(R)] complexes (R = bipyridine, phenanthroline): DFT study of antioxidant activity, DNA binding and evaluation of electron-donating and -withdrawing substituent groups | 10.1016/j.jmgm.2023.108577 | 2023 |
| Cyclodextrin-encapsulated new drug with promising anti-Trypanosoma cruzi activity | 10.1007/s10973-023-12403-x | 2023 |
| DFT calculations of copper complexes mimicking superoxide dismutase and docking studies and molecular dynamics of the transition metal complex binding to serum albumin | 10.1080/07391102.2023.2259479 | 2023 |
| Molecular dynamics simulations of aqueous systems of inhibitor candidates for adenosine-5?-phosphosufate reductase | 10.1080/07391102.2022.2033137 | 2023 |
| Molecular modeling of indazole-3-carboxylic acid and its metal complexes (Zn, Ni, Co, Fe and Mn) as NO synthase inhibitors: DFT calculations, docking studies and molecular dynamics simulations | 10.1016/j.inoche.2021.109120 | 2022 |
| Hydroxyl group interactions in metal dithiocarbamate complexes containing 2-hydroxyethyl substituents. Crystal structure determination, theoretical and Hirshfeld surface study of tris(2-hydroxyethyl(ethyl)amino-dithiocarbamato)indium(III). Survey of hydroxyl group interactions in metal tris(dithiocarbamato) complexes containing 2-hydroxyethyl substituents. | 10.1016/j.molstruc.2022.133783 | 2022 |
| Thiohydantoins and hydantoins derived from amino acids as potent urease inhibitors: Inhibitory activity and ligand-target interactions | 10.1016/j.cbi.2022.110045 | 2022 |
| Development of parameters compatible with the CHARMM36 force field for [Fe 4 S 4 ] 2+ clusters and molecular dynamics simulations of adenosine-5?-phosphosulfate reductase in GROMACS 2019 | 10.1080/07391102.2020.1847687 | 2022 |
| In Vitro Antimicrobial Screening of Benzoylthioureas: Synthesis, Antibacterial Activity toward and Molecular Docking Study | 10.1002/slct.202202117 | 2022 |
| In silico approach identified benzoylguanidines as SARS-CoV-2 main protease (M pro ) potential inhibitors | 10.1080/07391102.2022.2123396 | 2022 |
| Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on Leishmania amazonensis | 10.3390/antibiotics11101402 | 2022 |
| In silico approaches and in vitro assays identify a coumarin derivative as antiviral potential against SARS-CoV-2 | 10.1080/07391102.2022.2140203 | 2022 |
| Investigation of the antileishmanial activity and mechanisms of action of acetyl-thiohydantoins | 10.1016/j.cbi.2021.109690 | 2022 |
| Thiohydantoins as anti-leishmanial agents: n vitro biological evaluation and multi-target investigation by molecular docking studies | 10.1080/07391102.2020.1845979 | 2022 |
| Exploring the antileishmanial activity of N 1 , N 2 -disubstituted-benzoylguanidines: synthesis and molecular modeling studies | 10.1080/07391102.2021.1959403 | 2022 |
| Electronic investigation of the effect of substituents on the sod mimic activity of copper (II) complexes with 8-hydroxyquinoline-derived ligands | 10.1016/j.jinorgbio.2021.111359 | 2021 |
| Crystal structures, DFT calculations and Hirshfeld surface analysis of two (E)-3-(aryl)-1-(naphthalen-1-yl)prop-2-en-1-one chalcone derivatives, potential Mycobacterium tuberculosis Enoyl ACP reductase (InhA) inhibitors and optical materials: conformational differences within the prop-2-en-1-one unit | 10.1016/j.molstruc.2021.131091 | 2021 |
| Thiohydantoins as Potential Antioxidant Agents: In vitro and in silico evaluation | 10.1002/slct.202102840 | 2021 |
| Trypanocidal activity of new 1,6-diphenyl-1H-pyrazolo[3,4-b]pyridine derivatives: Synthesis, in vitro and in vivo studies | 10.1016/j.bmc.2020.115855 | 2021 |
| Biological evaluation and molecular modeling of peptidomimetic compounds as inhibitors for O-GlcNAc transferase (OGT) | 10.1016/j.ejps.2020.105510 | 2020 |
| Hexafluoroisopropanol (HFIP, CAS No 920-66-1) | 10.21577/1984-6835.20200104 | 2020 |
| In vitro evaluation of antitrypanosomal activity and molecular docking of benzoylthioureas | 10.1016/j.parint.2020.102225 | 2020 |
| Anti-Trypanosoma cruzi Activity and Molecular Docking Studies of 1Hpyrazolo[ 3, 4-b]pyridine Derivatives | 10.2174/1570180816666190305141733 | 2020 |
| 3-Acyltetramic acids as a novel class of inhibitors for human kallikreins 5 and 7 | 10.1016/j.bmcl.2019.02.031 | 2019 |
| Theoretical study of binuclear Cu-M complexes (M = Zn, Cu, Ni) with p-xylylene-bridged-bis(1,4,7-triazacyclononane) ligands: possible CuZnSOD mimics | 10.1016/j.ica.2019.119232 | 2019 |
| Synthesis of New Thiosemicarbazones and Semicarbazones Containing the 1,2,3-1H-triazole-isatin Scaffold: Trypanocidal, Cytotoxicity, Electrochemical Assays, and Molecular Docking | 10.2174/1573406414666180912120502 | 2019 |
| Anti-Mycobacterial Evaluation of 7-Chloro-4-Aminoquinolines and Hologram Quantitative Structure?Activity Relationship (HQSAR) Modeling of Amino?Imino Tautomers | 10.3390/ph10020052 | 2017 |
| Isosorbide-based peptidomimetics as inhibitors of Hepatitis C virus serine protease | 10.1016/j.bmcl.2017.07.027 | 2017 |
| Hologram QSAR Models of a Series of 6-Arylquinazolin-4-Amine Inhibitors of a New Alzheimer?s Disease Target: Dual Specificity Tyrosine-Phosphorylation-Regulated Kinase-1A Enzyme | 10.3390/ijms16035235 | 2015 |
| Aqueous Molecular Dynamics Simulations of the M. tuberculosis Enoyl-ACP Reductase-NADH System and Its Complex with a Substrate Mimic or Diphenyl Ethers Inhibitors | 10.3390/ijms161023695 | 2015 |
| Biological evaluation of pyrazinamide derivatives as an anticancer class | 10.17628/ecb.2014.3.358-361 | 2014 |
| Five N --benzylidene- N -methylpyrazine-2-carbohydrazides | 10.1107/s0108270113010056 | 2013 |
| Synthesis and Antitubercular Evaluation of N -Arylpyrazine and N,N¿ -Alkyl-diylpyrazine-2-carboxamide Derivatives | 10.1002/jhet.921 | 2012 |
| Structures of Two (E)-3-Substituted Cinnamoylbenzotriazole 1-Oxides | 10.1007/s10870-011-0260-y | 2012 |
| In vitro anti-mycobacterial activity of (E)-N´-(monosubstituted-benzylidene) isonicotinohydrazide derivatives against isoniazid-resistant strains | 10.4081/idr.2012.e13 | 2012 |
| ?-[( )-2-Methoxybenzylidene]pyrazine-2-carbohydrazide | 10.1107/S1600536811022938 | 2011 |
| Pyrazinamide: An Essential Drug in the Tuberculosis Treatment | 10.5935/1984-6835.20110021 | 2011 |
| Synthesis and Antimycobacterial Evaluation of N-(E)-heteroaromaticpyrazine-2-carbohydrazide Derivatives | 10.2174/157340611795564303 | 2011 |
| Structures of (pyrazinecarbonyl)hydrazones of substituted benzaldehydes: supramolecular arrangements generated by various intermolecular contacts | 10.1524/zkri.2010.1209 | 2010 |
| Structures of (pyrazinecarbonyl)hydrazones of substituted benzaldehydes: different supramolecular arrangements from C¿H···X (X = O, N, ?) hydrogen bonds | 10.1524/zkri.2010.1235 | 2010 |
| (Pyrazinecarbonyl)hydrazones of heteroarenealdehydes: crystal structures formed from N¿H···O, N¿HN, C¿H···O hydrogen-bonds, C¿H···? and ?···? interactions | 10.1524/zkri.2010.1248 | 2010 |
| Hydrated (pyrazinecarbonyl)hydrazones of hydroxy and methoxy substituted benzaldehydes | 10.1524/zkri.2010.1267 | 2010 |
| -(2-Chloroethyl)pyrazine-2-carboxamide | 10.1107/S1600536810041656 | 2010 |
| Synthesis and Cytotoxic Evaluation of Disubstituted N-Acylhydrazones Pyrazinecarbohydrazide Derivatives | 10.2174/157018010790945814 | 2010 |
| Synthesis and antimycobacterial evaluation of N¿-[(E)-(monosubstituded-benzylidene)]-2-pyrazinecarbohyrazide derivatives | 10.1016/j.ejmech.2009.08.009 | 2009 |
| (Pyrazinecarbonyl)hydrazone halobenzaldehydes: supramolecular arrays generated by face to face stacking of ribbons, formed from C¿H¿O interactions | 10.1524/zkri.2009.1182 | 2009 |
| Synthesis and Biological Evaluation of N,N'-di(thiopheneacetyl)diamines Series as Antitubercular Agents | 10.1080/10426500802049803 | 2008 |
| Produtos Naturais em Fase Avançada de Testes Clínicos no Tratamento contra o Câncer | 2007 |
Eventos:
(100.00% eventos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Planning of new heterocyclic compounds targeting class I PI3Ks for cancer therapy | 10.3390/ECMC2021-11482 | 2021 |
| New 1,6-diphenyl-1<em>H</em>-pyrazolo[3,4-b]pyridine derivatives with potent antichagasic activitys | 10.3390/ecmc-4-05610 | 2018 |