| Inhibitor of serine peptidase 2 (ISP2) of Leishmania major modulates parasite interaction with neutrophils |
|
2011 |
| Substrate inhibition and allosteric modulation of brucipain by heparan sulfate |
|
2011 |
| The inhibition of cysteine cathepsins in embryonic stem cells promotes neual differentiation |
|
2011 |
| Leishmania major inhibitor of serine peptidases, ISP2, prevents the activation of mammalian PKR, promoting parasite survival in macrophages |
|
2011 |
| Substrate inhibition and allosteric modulation of brucipain by heparan sulfate |
|
2011 |
| Cruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus midgut |
|
2011 |
| Trypanosoma cruzi invades host cells through the activation of endothelin and bradykinin receptors: a converging pathwayleading to chagasic vasculopathy |
|
2011 |
| Characterization of serine peptidase inhibitor (ISP2) of Trypanosoma cruzi |
|
2011 |
| Characterisation of the putative sialoglyco metallopeptidase-like gene of Leishmania major |
|
2011 |
| Cruzipain promotes Trypanosoma cruzi adhesion to Rhodnius prolixus explanted midguts |
|
2010 |
| Leishmania major encoded inhibitors of serine peptidase (ISPs) modulate de uptake and release of parasite from murine neutropils |
|
2010 |
| Infuence of Ecotin-like serine peptidase inhibitors of Leishmania major in parasite internalization and survival in murine dendritic cells |
|
2010 |
| Role of natural inhibitor of cysteine peptidase in Trypanosoma brucei. |
|
2009 |
| Influence on host cell invasion by serine peptidase inhibitor (ISP2) of Trypanosoma cruzi. |
|
2008 |
| Influence of inhibitors of serine peptidases of Leishmania major in the early stage of infection. |
|
2008 |
| Intracellular sorting of phosphoglucomutase to glycosomes in Trypanosoma cruzi. |
|
2008 |
| ICP regulation of Trypanosoma brucei cysteine peptidases: influence on parasite traversal of the blood brain barrier. |
|
2007 |
| Modulation of host neutrophil elastase by ecotin-like serine peptidase inhibitors (ISP) of Leishmania major: influence on parasite infectivity and survival. |
|
2007 |
| Characterization of Trypanosoma cruzi p67: a putative reservosome marker. |
|
2007 |
| The phosphoglucomutase (PGM) of Trypanosoma cruzi: mapping the import motifs responsible for the intracellular sorting to glycosomes. |
|
2007 |
| Characterization of the serine peptidase inhibitor (ISP2) of Trypanosoma cruzi. |
|
2007 |
| Distinct pathways of smooth muscle invasion by Trypanosoma cruzi Dm28 trypomastigotes: Differential roles of G Protein-coupled receptors, adenylyl cyclase and PI3 kinase mediated signaling. |
|
2006 |
| African trypanosomes traversal of the human blood-brain barrier requires cysteine protease mediated calcium signaling. |
|
2006 |
| Structural basis for the inhibitory function of chagasin: Different requirements for the inhibition of parasite versus host cysteine proteases. |
|
2006 |
| Role of ecotin-like serine peptidase inhibitors of Leishmania major in parasite internalization and survival in murine macrophages. |
|
2006 |
| Phosphoglucomutase (PGM) is located in the glycosomes of Trypanosoma cruzi. |
|
2006 |
| Molecular and biochemical characterization of the acyl-CoA-dependent ceramide synthase gene in Trypanosoma cruzi. |
|
2006 |
| Antileishmanial chalcones with increased in vitro activity against African trypanosomes. |
|
2006 |
| Trypanosomatid drug resistance: some cellular facets. |
|
2006 |
| Studies on the sub-cellular localization of phosphoglucomutase (PGM) in Trypanosoma cruzi. |
|
2005 |
| Alterations in traffic and pro-cruzipain maturation in Trypanosoma cruzi overexpressing chagasin. |
|
2005 |
| Studies on the chagasin family of cysteine peptidase inhibitors. |
|
2005 |
| Alterations in Traffic, Lipid Biosynthesis and Pro-Cruzipain Maturation in Trypanosoma cruzi Overexpressing Chagasin. |
|
2005 |
| The Substrate specificity of the cysteine peptidase of Trypanosoma b. brucei, brucipain and its inactivation by natural cysteine peptidase inhibitors. |
|
2005 |
| Potent inhibition of cathepsin F and of cysteine proteases from trypanosomes (cruzipain and brucipain) by the propeptide of cruzipain. |
|
2005 |
| Interplay between parasite cysteine proteases and the host kinin system modulates vascular leakage and macrophage infection by promastigotes of the Leishmania donovani complex. |
|
2005 |
| Brucipain takes a tryp across the Blood-Brain Barrier. |
|
2005 |
| Chagasin contributes to post-transcriptional regulation of cruzipain function. |
|
2004 |
| Cloning and heterologous expression of the cysteine protease from Trypanosoma brucei brucei (brucipain) and characterization of temperature dependent substrate inhibition. |
|
2004 |
| High affinity inhibition of cysteine proteases from diverse pathogenic trypanosomatids by the pro domain of cruzipain. |
|
2004 |
| Heterologous expression of Trypanosoma cruzi phosphoglucomutase (PGM) in Saccharomyces cerevisiae and functional complementation of yeast pgm null mutant. |
|
2004 |
| The activation of precursor forms of the T. cruzi main cysteine protease, cruzipain, is modulated by glycosaminoglicans and by mildly acidic pH. |
|
2004 |
| Modulation of the cysteine protease of T. brucei brucei (brucipain) by glycosaminoglicans and enzyme inactivation by the N-terminal domain (pro domain) of cruzipain. |
|
2004 |
| Role of dibucaine in the endocytic and exocytic pathway of epimastigote forms of Trypanosoma cruzi. |
|
2004 |
| Analysis of the phosphoglucomutase (PGM) gene among different stocks of T. cruzi. |
|
2004 |
| Chronic heart fibrosis is attenuated in B1 knockout mice infected by Trypanosoma cruzi. |
|
2004 |
| Cloning and expression of a recombinant cysteine protease (TFCP1) from Thrithrichomonas foetus. |
|
2003 |
| Post-Transcriptional regulation of cruzipain by the endogenous inhibitor chagasin |
|
2003 |
| Cloning, expression and characterization of the cysteine proteases from Trypanosoma brucei brucei (brucipain) and Leishmania donovani. |
|
2003 |
| Potent inhibition of trypanosomatid cysteine proteases by the pro domain of cruzipain. |
|
2003 |
| Cloning and characterization of the phosphoglucomutase (PGM) gene from Trypanosoma cruzi. |
|
2003 |
| Chagasin regulates cruzipain activity, maturation and intracellular traffic in Trypanosoma cruzi. |
|
2003 |
| Targeting of Trypanosoma cruzi cysteine proteinases by synthetic inhibitors depends on endocytosis. |
|
2002 |
| Heparan sulfate modulates kinin release by Trypanosoma cruzi through the activity of cruzipain. |
|
2002 |
| Maturation of pro-cruzipain1 by cruzipain2: Evidence for trans-activation "in vivo". |
|
2002 |
| Over-expression of chagasin, a cysteine protease inhibitor of T. cruzi, modulates the maturation of pro-cruzipain and the suceptibility of epimastigotes to synthetic cysteine protease inhibitors. |
|
2002 |
| Characterization of chagasin-like cysteine protease inhibitors in Leishmania amazonensis, Leishmania donovani and Tritrichomonas foetus. |
|
2001 |
| Heparan sulfate modulates kinin-release by Trypanosoma cruzi through the activity of cruzipain. |
|
2001 |
| Activation of the inducible B1-kinin receptor (B1) by Trypanosoma cruzi: host cell susceptibility. |
|
2001 |
| Infectivity of Trypanosoma cruzi trypomastigotes depends on the activity of extracellular cruzipain. |
|
2001 |
| Correlation between cruzipain expression and Trypanosoma cruzi infectivity "in vitro" |
|
2000 |
| Signaling through the inducible bradykinin receptor (B1R) increases host cell suceptibility to invasion by Trypanosoma cruzi. |
|
2000 |
| Specificity determinants of cruzipain isoforms |
|
2000 |
| Protozoa cystine-proteases as markers for the study of endocytic function in primitive eucaryotic cells |
|
2000 |
| Substrate specificity of a major cysteine proteinase from Plasmodium falciparum (falcipain) characterized by fluorescent internally quenched substrates. |
|
2000 |
| Molecular dynamics simulation of cruzain and cruzipain 2: the S2 specificity pocket. |
|
2000 |
| Molecular basis of activation of vascular endothelium by Trypanosoma cruzi: role of kininogens, kinins and bradykinin receptors. |
|
2000 |
| Characterization of the substrate specificity of cysteine protease isoforms from Trypanosoma cruzi: a comparative study between cruzipain 2 and cruzain. |
|
1999 |
| Expression of cruzipain and of a cathepsin B like target (Tc-cb) is inverted in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine proteinases. |
|
1999 |
| Gene transfection of Trypanosoma cruzi with a minor cysteine proteinase isoform (cruzipain 2) but not cruzain, potentiates trypomastigote infectivity in mammalian cells "in vitro". |
|
1999 |
| Molecular modeling of the inhibition of cysteine proteases from Trypanosoma cruzi by E-64. |
|
1998 |
| Molecular characterization of chagasin, a Trypanosoma cruzi inhibitor of papain like cysteinyl proteinases. |
|
1998 |
| The transfection of Trypanosoma cruzi cell lines with the gene of the cysteine protease isoform cruzipain 2 enhances parasite infectivity in host cells. |
|
1998 |
| Trypanosoma cruzi resistance to synthetic inhibitors of cysteine-proteinases correlates with changes in the expression of target enzymes and membrane permeability. |
|
1998 |
| Recombinant cysteine protease isoforms from Trypanosoma cruzi (Cruzain and cruzipain 2) show marked differences to inhibitor sensitivity. |
|
1998 |
| Inhibition studies of cysteine proteases from Trypanosoma cruzi by molecular modeling. |
|
1998 |
| Immunochemical characterization of cruzipain isoforms during Trypanosoma cruzi development. |
|
1998 |
| Preliminary characterization of Trypanosoma cruzi cell lines transfected with the cysteine protease isoform cruzipain 2. |
|
1997 |
| Multiple mechanisms determine drug resistance against peptidyl-based inhibitors of Trypanosoma cruzi. |
|
1997 |
| Characterization of a Trypanosoma cruzi population resistant to synthetic irreversible cysteine protase inhibitors. |
|
1996 |
| The kinin releasing activity of cysteinyl proteinases from Trypanosoma cruzi: a factor of parasite virulence and pathogenicity ? |
|
1996 |
| The Major Cysteine Proteinase From Trypanosoma Cruzi: Phenotypic Cha- Racterization Of A Parasite Sub-Population Selected For Resistance Against Irreversible Synthetic Inhibitors. |
|
1995 |
| The Minor Cysteine Proteinase From Trypanosoma Cruzi:Identification Inparasite Population Selected For Resistance To Synthetic Inhibitors. |
|
1995 |
| Synthesis cf coumarin-containing peptides and their hydrolysis by cysteine proteases. |
|
1995 |
| Preliminary Characterization Of Recombinant Cruzipain 2, A New Cystei-Ne Protease Isoform From Trypanosoma Cruzi. |
|
1994 |
| Structure And Functional Diversities In Trypanosoma Cruzi Cysteinyl Protease. |
|
1994 |
| Genetic Diversity Of Cysteinyl Proteinases From Trypanosoma Cruzi. |
|
1993 |
| Temperature dependent substrate inhibition of the cysteine protease (Gp57/51) from Trypanosoma cruzi. |
|
1992 |
| Cloning and expression of cruzipain 2, a new cysteine protease of Trypanosoma cruzi. |
|
1992 |
| Cloning Of Cruzipain 2, A New Cysteine Protease From Trypanosoma Cruzi |
|
1992 |
