Bruno Lourenço Diaz

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Gabinete do Diretor do Instituto de Biofísica

e-mail:

bldiaz@biof.ufrj.br

Linkedin:

www.linkedin.com/in/bruno-l-diaz

Google Scholar:

https://scholar.google.com/citations?user=h4sSucQAAAAJ&hl=en

ORCID:

https://orcid.org/0000-0001-8393-3823

Formação:
  • Harvard Medical School

    | Pós-Doutorado | 1998 - 2002
  • Fundação Oswaldo Cruz

    Biologia Celular e Molecular | Doutorado | 1995 - 1998
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas | Graduação | 1990 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:

(81.58% artigos com DOI)

Titulo DOI Ano
Considerations for continued expansion of the Brazilian post-graduate system 10.3389/feduc.2023.987200 2023
Assessment of the Brazilian postgraduate evaluation system 10.3389/feduc.2022.1036108 2022
Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD2 paracrine activity in vitro 10.1016/j.cellimm.2021.104316 2021
Lysophosphatidic acid (LPA) as a modulator of plasma membrane Ca2+-ATPase from basolateral membranes of kidney proximal tubules 10.1007/s13105-021-00800-5 2021
Acute catabolism of leukocyte lipid bodies: Characterization of a nordihydroguaiaretic acid (NDGA)-induced proteasomal-dependent model 10.1016/j.plefa.2021.102320 2021
Zika Virus Infects Human Placental Mast Cells and the HMC-1 Cell Line, and Triggers Degranulation, Cytokine Release and Ultrastructural Changes 10.3390/cells9040975 2020
Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis 10.1186/s13287-020-01889-z 2020
Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2 10.3389/fendo.2020.572113 2020
Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells 10.3389/fonc.2019.00116 2019
Glucagon reduces airway hyperreactivity, inflammation, and remodeling induced by ovalbumin 10.1038/s41598-019-42981-6 2019
Eicosapentaenoic acid potentiates the therapeutic effects of adipose tissue-derived mesenchymal stromal cells on lung and distal organ injury in experimental sepsis 10.1186/s13287-019-1365-z 2019
Leukotriene B4 in equine asthma syndrome: what do we know so far? 10.1590/1678-5150-pvb-6016 2019
Eicosapentaenoic Acid Enhances the Effects of Mesenchymal Stromal Cell Therapy in Experimental Allergic Asthma 10.3389/fimmu.2018.01147 2018
The allergic response mediated by fire ant venom proteins 10.1038/s41598-018-32327-z 2018
Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors 10.3389/fimmu.2018.02139 2018
Development and Characterization of Nanoemulsion Containing Almond Oil, Biodegradable Polymer and Propranolol as Potential Treatment in Hemangioma 10.1002/masy.201800121 2018
Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary 10.1155/2017/4156361 2017
Bone Marrow, Adipose, and Lung Tissue-Derived Murine Mesenchymal Stromal Cells Release Different Mediators and Differentially Affect Airway and Lung Parenchyma in Experimental Asthma 10.1002/sctm.16-0398 2017
Effects of Bone Marrow Mesenchymal Stromal Cell Therapy in Experimental Cutaneous Leishmaniasis in BALB/c Mice Induced by Leishmania amazonensis 10.3389/fimmu.2017.00893 2017
Establishment of primary mixed cell cultures from spontaneous canine mammary tumors: Characterization of classic and new cancer-associated molecules 10.1371/journal.pone.0184228 2017
Polyunsaturated fatty acids and endocannabinoids in health and disease 10.1080/1028415x.2017.1347373 2017
Regular and moderate aerobic training before allergic asthma induction reduces lung inflammation and remodeling 10.1111/sms.12614 2016
Group V Secretory Phospholipase A2 Is Involved in Tubular Integrity and Sodium Handling in the Kidney 10.1371/journal.pone.0147785 2016
Respiratory and Systemic Effects of LASSBio596 Plus Surfactant in Experimental Acute Respiratory Distress Syndrome 10.1159/000443037 2016
Efficacy of intranasal LaAg vaccine against Leishmania amazonensis infection in partially resistant C57Bl/6 mice 10.1186/s13071-016-1822-9 2016
BIOMICROSCOPIA ULTRASSÔNICA - UM ALIADO NO DIAGNÓSTICO DA METÁSTASE NO MELANOMA - ESTUDO EM ANIMAIS 2016
Cyclo-Gly-Pro, a cyclic dipeptide, attenuates nociceptive behavior and inflammatory response in mice 10.1111/1440-1681.12480 2015
P2×7 purinergic signaling in dilated cardiomyopathy induced by auto-immunity against muscarinic M2 receptors: autoantibody levels, heart functionality and cytokine expression 10.1038/srep16940 2015
Intravenous Glutamine Administration Reduces Lung and Distal Organ Injury in Malnourished Rats With Sepsis 10.1097/shk.0000000000000102 2014
Effects of bone marrow mononuclear cells from healthy or ovalbumin-induced lung inflammation donors on recipient allergic asthma mice 10.1186/scrt496 2014
Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema 10.1186/s12931-014-0118-x 2014
DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma 10.1016/j.jconrel.2014.02.010 2014
Bone marrow mononuclear cell therapy in experimental allergic asthma: Intratracheal versus intravenous administration 10.1016/j.resp.2012.11.005 2013
Bone Marrow-Derived Mononuclear Cells Promote Improvement in Glomerular Function in Rats with Early Diabetic Nephropathy 10.1159/000354473 2013
Impact of Bacillus Calmette-Guérin Moreau vaccine on lung remodeling in experimental asthma 10.1016/j.resp.2013.07.025 2013
Bone marrow-derived mononuclear cells vs. mesenchymal stromal cells in experimental allergic asthma 10.1016/j.resp.2013.03.014 2013
Effects of Mesenchymal Stem Cell Therapy on the Time Course of Pulmonary Remodeling Depend on the Etiology of Lung Injury in Mice 10.1097/ccm.0b013e31828a663e 2013
Regular and moderate exercise before experimental sepsis reduces the risk of lung and distal organ injury. 10.​1152/​japplphysiol.​01061.​2011 2012
Hypertonic Stress Induces VEGF Production in Human Colon Cancer Cell Line Caco-2: Inhibitory Role of Autocrine PGE2 10.1371/journal.pone.0025193 2011
Eosinophils as a Novel Cell Source of Prostaglandin D2: Autocrine Role in Allergic Inflammation 10.4049/jimmunol.1101806 2011
Bone marrow-derived mononuclear cell therapy in experimental pulmonary and extrapulmonary acute lung injury 10.1097/CCM.0b013e3181e796d2 2010
Co-operative signalling through DP1 and DP2 prostanoid receptors is required to enhance leukotriene C4 synthesis induced by prostaglandin D2 in eosinophils 10.1111/j.1476-5381.2010.01086.x 2010
Cytosolic phospholipase A2-driven PGE2synthesis within unsaturated fatty acids-induced lipid bodies of epithelial cells? 10.1016/j.bbalip.2009.01.003 2009
Leukotriene B4 mediates    T lymphocyte migration in response to diverse stimuli 10.1189/jlb.0809563 2009
Hypertonic environment elicits cyclooxygenase-2-driven prostaglandin E2 generation by colon cancer cells: Role of cytosolic phospholipase A2-? and kinase signaling pathways? 10.1016/j.plefa.2009.11.005 2009
Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells 10.1186/1471-2121-9-63 2008
Cutting Edge: Prostaglandin D2 Enhances Leukotriene C4 Synthesis by Eosinophils during Allergic Inflammation: Synergistic In Vivo Role of Endogenous Eotaxin. 2006
Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner 10.1016/j.bbalip.2006.09.009 2006
Auto-antibodies in prostate cancer: Humoral immune response to antigenic determinants coded by the differentially expressed transcripts FLJ23438 and VAMP3 10.1002/pros.20439 2006
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats. 10.1016/j.ejphar.2005.02.011 2005
A novel effect for annexin 1-derived peptide Ac2-26: reduction of allergic inflammation in the rat. 10.1124/jpet.104.080473 2005
Role of secretory phospholipase A(2) in IL-6 and VEGF production by mast cells 2005
Role of cytosolic PLA(2) na kinase signaling pathways on PGE(2) generation by a colon cancer cell line 2005
Diabetes and Cancer: the effect of hyperglycemia in metastatic development 2005
Role of group V phospholipase A2 in zymozan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption 10.1074/jbc.M313748200 2004
Role of group V phospholipase A(2) in zymosan-induced eicosanoidgeneration and vascular permeability revealed by targeted gene disruption 2004
Adoptive transfer of mast cells abolishes the inflammatory refractoriness to allergen in diabetic rats 10.1159/000071489 2003
Phospholipase A2 10.1016/S0952-3278(03)00069-3 2003
Systemic anaphylaxis is prevented in alloxan-diabetic rats by a mechanism dependent on glucocorticoids 10.1016/S0014-2999(03)01934-4 2003
Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids 2002
Inhibition of allergen-induced eosinophil migration by lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 2002
Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells 2002
Enhanced serum glucocorticoid levels mediate the reductionof serosal mast cell numbers in diabetic rats 10.1016/S0024-3205(01)01087-6 2001
Exogenous but not endogenous prostanoids regulate COX-2 induction in mouse mast cells 2001
Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia 2000
Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking. 2000
Mechanism underlying acute resident leukocyte disappearance induced by immunological and non-immunological stimuli in rats: evidence for a role for the coagulation system 10.1007/s000110050650 2000
Differential regulation of cytokine-dependent COX-2 and IL-6 expression by PGE(2) and 15d-PGJ(2) in mouse mast cells 2000
Antigen-induced pleural eosinophilia is suppressed in diabetic rats: role of corticosteroid hormones 10.1590/s0074-02761997000800031 1997
Anti-Allergic Properties of the Natural PAF Antagonist Yangambin 10.1055/s-2006-957654 1997
Local Exposure To Salbutamol Or Bt2 Cyclic Amp Inhibits Pleural Exudation And Leukocyte Influx Caused By Antigen In Rats 10.1016/0014-2999(95)00694-X 1996
Selective Inhibition Of Phosphodiesterase Type Iv Suppresses The Chemotactic Responsiveness Of Rat Eosinophils In Vitro 10.1016/0014-2999(96)00357-3 1996
Alloxan Diabetes Reduces Pleural Mast Cell Numbers and the Subsequent Eosinophil Influx Induced by Allergen in Sensitized Rats 10.1159/000237343 1996
Salbutamol and dibutyryl cyclic AMP inhibit microvascular leakage and leucocyte infiltration caused by antigen in actively sensitized rats 1994
Suppression by cetirizine of pleurisy triggered by antigen in actively sensitized rats. 10.1016/0014-2999(92)90811-H 1992
Pharmacological Modulation of the Late Eosinophilia Induced by Antigen in Actively Sensitized Rats 10.1159/000236211 1992
Eventos:

(1.92% eventos com DOI)

Titulo DOI Ano
EFFECTS OF GLUTAMINE THERAPY IN EXPERIMENTAL PULMONARY AND EXTRAPULMONARY ACUTE LUNG INJURY 2011
EFFECTS OF REGULAR AND MODERATE AEROBIC EXERCISE ON AIRWAY AND LUNG PARENCHYMA REMODELING IN A MURINE MODEL OF CHRONIC ALLERGIC ASTHMA 2011
LEUKOTRIENE B4/BLT1 MEDIATES γδ T LYMPHOCYTE MIGRATION DURING INFLAMMATION 2011
Secretory type group V PLA2: possible role in renal physiology 2011
Role of Prolactin and Glucocorticoid Receptor Interactions in the Thymus Atrophy Occurring During Experimental Trypanosoma Cruzi Infection 2011
Cooperative DP1- and CRTH2-activated signalling is required to elicit enhanced leukotriene C4 synthesis induced by prostaglandin D2 within eosinophils 2010
PHOSPHOLIPASE A2 GROUP V IN LEISHMANIASIS: ROLE IN IMMUNITY 2010
Eosinophils as novel cell source of prostaglandin D2: autocrine activity and allergy-driven synthesis 2010
LEUKOTRIENE B4 MEDIATES γδ T LYMPHOCYTE MIGRATION IN RESPONSE TO DIVERSE STIMULI 2010
IN VITRO-DIFFERENTIATED MOUSE EOSINOPHILS AS A NEW TOOL FOR THE STUDY OF EOSINOPHIL BIOLOGY. 2010
Glucose starvation induces melanogenesis in B16F10 MURINE MELANOMA CELLS through oxidative stress 2010
Glucose starvation induces melanogenesis in B16F10 in mouse melanoma cells through oxidative stress 2010
Glucose starvation induces melanogenesis in B16F10 mouse melanoma cells through oxidative stress 2010
Activation of PGD receptors, DP1 and CRTH2, elicits 2 complementary signaling that evokes LTC4 secretion from eosinophils 2009
Bradykinin activates human eosinophils: role of endogenous PGE2 in induction of lipid body biogenesis 2009
Human eosinophils synthesize PGD : autocrine function in eosinophil activation 2009
Leukotriene B4 mediates gamma delta T lymphocyte migration in response to diverse stimuli 2009
Cytosolic phospholipase A2-driven arachidonic acid mobilization within newly assembled lipid bodies of epithelial cells 2008
MIgração induzida por heme depende da via da 5-lipoxigenase 2007
PGD2 elicits differential release of pre-formed cytokines from eosinophils: cooperative signaling between DP and CRTH2 receptors 2007
Role of cytosolic PLA2 and kinase signaling pathways on PGE2 generation by a colon cancer cell line 2006
PGD2 controls LTC2 synthesis by eosinophils during allergic inflammation: synergistic role of endogenous eotaxin 2006
Modulation of lipid body in epithelial cells 2006
Estudo da Modulação de corpúsculos lipídicos em células epiteliais 2006
SECRETION OF CXC CHEMOKINE BY MACROPHAGES LINKS TLR2-DEPENDET SENSING OF Trypanosoma cruzi to MECHANISMS THAT STEER INNATE IMMUNITY VIA BRADYKININ RECEPTORS 2006
SECRETION OF CHEMOKINES BY MACROPHAGES LINKS TLR2-DEPENDENT SENSING OF Trypanosoma cruzi TO MECHANISMS THAT STEER INNATE IMMUNITY VIA BRADYKININ RECEPTORS 2006
Estudo da modulação de Corpúsculos lipídicos em Células epiteliais e endoteliais. 2005
Role of group V phospholipase A2 in eicosanoid generation revealed by gene disruption 2004
Role of secretory phospholipases A2 in IL-6 and VEGF production by mast cells 2004
Role of phospholipases A2 in COX-2 induction in colon cancer cell line Caco-2 2004
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats 2004
Role of secretory phospholipases A2 in IL-6 production by mast cells and macrophages 2004
Papel de Fosfolipase A2 Secretória na Expressão de COX-2 e Produção de VEGF em Câncer de Cólon 2003
Papel de Fosfolipase A2 Secretória na Produção de IL-6 por Mastócitos Derivados de Medula Óssea 2003
Novel Phenoxi-phtalimid Acid Derivative LASSBIO 552 Caused a Selective Inhibition of Allergen-Evoked Eosinophil Recruitment in Sensitized Rats 2003
Phsopholipase A2 and the Regulation of Eicosanoid Biosynthesis in Mouse Mast Cells 2001
Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking in rats 1999
Cytosolic phospholipase A is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells 10.1016/S0090-6980(99)90274-5 1999
Antigen-Induced Eosinophilia In Experimental Diabetes: Role Of Endogenous Corticosteroids And Mast Cells. 1997
Production And Distribution Of Eosinophils In Parasitic Infection By Agiostrogylus Costaricencis In Wistar Rats. 1997
Hyporesponsiveness Of Mast Cell Population In Experimental Diabetes: Involvement Of Endogenous Corticosteroids. 1996
Detection Of A Soluble Eosinophilopoietic Factor In Parasitic Infection By Angiostrongylus Costaricencis In Wistar Rats 1996
Reduction Of Mast Cell Population In Experimental Diabetes: Role Of Endogenous Corticosteroids 1996
Hyporesponsiveness Of Mast Cell Population In Experimental Diabetes: Involvement Of Endogenous Corticosteroids. 1996
Alloxan-Diabetes Reduces Pleural Mast Cell Numbers And Antigen-Induced Eosinophilia In Sensitised Rats: Role Of Insulin And Corticosteroids 1996
Selective Inhibition Of Phosphodiesterase Type Iv Suppresses The Chemotactic Responsiveness Of Rat Eosinophils In Vitro 1996
Efeito da Lignana Yangambina Sobre A Resposta Inflamatória Alérgica Pleural Em Ratos Ativamente Sensibilizados. 1995
Yangambina Inibe Trombocitopenia Induzida Por Antígeno Em Ratos Ativamente Sensibilizados: Evidência do Envolvimento de Paf. 1995
Insulin Modulatory Effect On Pleural Mast Cell Population In Alloxan-Diabetic Rats. 1995
Papel dos Mastócitos No Comprometimento da Resposta Pleural Alérgica Observada Em Ratos Diabéticos. 1994
Efeito de Inibidores Seletivos de Fosfodiesterases Sobre A Eosinofilia Pleural Alérgica Em Ratos: Interação Com Salbutamol. 1994
Effect Of Selective Phosphodiesterase Inhibitors On The Eosinophil Chemotaxis Induced By LTB4 In Vitro 1994
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