Bruno Lourenço Diaz
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Gabinete do Diretor do Instituto de Biofísica
e-mail:
bldiaz@biof.ufrj.br
Linkedin:
www.linkedin.com/in/bruno-l-diaz
Google Scholar:
https://scholar.google.com/citations?user=h4sSucQAAAAJ&hl=en
ORCID:
https://orcid.org/0000-0001-8393-3823
Formação:
-
Harvard Medical School
| Pós-Doutorado | 1998 - 2002
-
Fundação Oswaldo Cruz
Biologia Celular e Molecular | Doutorado | 1995 - 1998
-
Universidade Federal do Rio de Janeiro
Ciências Biológicas | Graduação | 1990 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:
(81.58% artigos com DOI)
Titulo | DOI | Ano |
---|---|---|
Considerations for continued expansion of the Brazilian post-graduate system | 10.3389/feduc.2023.987200 | 2023 |
Assessment of the Brazilian postgraduate evaluation system | 10.3389/feduc.2022.1036108 | 2022 |
Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD2 paracrine activity in vitro | 10.1016/j.cellimm.2021.104316 | 2021 |
Lysophosphatidic acid (LPA) as a modulator of plasma membrane Ca2+-ATPase from basolateral membranes of kidney proximal tubules | 10.1007/s13105-021-00800-5 | 2021 |
Acute catabolism of leukocyte lipid bodies: Characterization of a nordihydroguaiaretic acid (NDGA)-induced proteasomal-dependent model | 10.1016/j.plefa.2021.102320 | 2021 |
Zika Virus Infects Human Placental Mast Cells and the HMC-1 Cell Line, and Triggers Degranulation, Cytokine Release and Ultrastructural Changes | 10.3390/cells9040975 | 2020 |
Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis | 10.1186/s13287-020-01889-z | 2020 |
Leptin Elicits In Vivo Eosinophil Migration and Activation: Key Role of Mast Cell-Derived PGD2 | 10.3389/fendo.2020.572113 | 2020 |
Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells | 10.3389/fonc.2019.00116 | 2019 |
Glucagon reduces airway hyperreactivity, inflammation, and remodeling induced by ovalbumin | 10.1038/s41598-019-42981-6 | 2019 |
Eicosapentaenoic acid potentiates the therapeutic effects of adipose tissue-derived mesenchymal stromal cells on lung and distal organ injury in experimental sepsis | 10.1186/s13287-019-1365-z | 2019 |
Leukotriene B4 in equine asthma syndrome: what do we know so far? | 10.1590/1678-5150-pvb-6016 | 2019 |
Eicosapentaenoic Acid Enhances the Effects of Mesenchymal Stromal Cell Therapy in Experimental Allergic Asthma | 10.3389/fimmu.2018.01147 | 2018 |
The allergic response mediated by fire ant venom proteins | 10.1038/s41598-018-32327-z | 2018 |
Leptin Elicits LTC4 Synthesis by Eosinophils Mediated by Sequential Two-Step Autocrine Activation of CCR3 and PGD2 Receptors | 10.3389/fimmu.2018.02139 | 2018 |
Development and Characterization of Nanoemulsion Containing Almond Oil, Biodegradable Polymer and Propranolol as Potential Treatment in Hemangioma | 10.1002/masy.201800121 | 2018 |
Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary | 10.1155/2017/4156361 | 2017 |
Bone Marrow, Adipose, and Lung Tissue-Derived Murine Mesenchymal Stromal Cells Release Different Mediators and Differentially Affect Airway and Lung Parenchyma in Experimental Asthma | 10.1002/sctm.16-0398 | 2017 |
Effects of Bone Marrow Mesenchymal Stromal Cell Therapy in Experimental Cutaneous Leishmaniasis in BALB/c Mice Induced by Leishmania amazonensis | 10.3389/fimmu.2017.00893 | 2017 |
Establishment of primary mixed cell cultures from spontaneous canine mammary tumors: Characterization of classic and new cancer-associated molecules | 10.1371/journal.pone.0184228 | 2017 |
Polyunsaturated fatty acids and endocannabinoids in health and disease | 10.1080/1028415x.2017.1347373 | 2017 |
Regular and moderate aerobic training before allergic asthma induction reduces lung inflammation and remodeling | 10.1111/sms.12614 | 2016 |
Group V Secretory Phospholipase A2 Is Involved in Tubular Integrity and Sodium Handling in the Kidney | 10.1371/journal.pone.0147785 | 2016 |
Respiratory and Systemic Effects of LASSBio596 Plus Surfactant in Experimental Acute Respiratory Distress Syndrome | 10.1159/000443037 | 2016 |
Efficacy of intranasal LaAg vaccine against Leishmania amazonensis infection in partially resistant C57Bl/6 mice | 10.1186/s13071-016-1822-9 | 2016 |
BIOMICROSCOPIA ULTRASSÔNICA - UM ALIADO NO DIAGNÓSTICO DA METÁSTASE NO MELANOMA - ESTUDO EM ANIMAIS | 2016 | |
Cyclo-Gly-Pro, a cyclic dipeptide, attenuates nociceptive behavior and inflammatory response in mice | 10.1111/1440-1681.12480 | 2015 |
P2×7 purinergic signaling in dilated cardiomyopathy induced by auto-immunity against muscarinic M2 receptors: autoantibody levels, heart functionality and cytokine expression | 10.1038/srep16940 | 2015 |
Intravenous Glutamine Administration Reduces Lung and Distal Organ Injury in Malnourished Rats With Sepsis | 10.1097/shk.0000000000000102 | 2014 |
Effects of bone marrow mononuclear cells from healthy or ovalbumin-induced lung inflammation donors on recipient allergic asthma mice | 10.1186/scrt496 | 2014 |
Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema | 10.1186/s12931-014-0118-x | 2014 |
DNA nanoparticle-mediated thymulin gene therapy prevents airway remodeling in experimental allergic asthma | 10.1016/j.jconrel.2014.02.010 | 2014 |
Bone marrow mononuclear cell therapy in experimental allergic asthma: Intratracheal versus intravenous administration | 10.1016/j.resp.2012.11.005 | 2013 |
Bone Marrow-Derived Mononuclear Cells Promote Improvement in Glomerular Function in Rats with Early Diabetic Nephropathy | 10.1159/000354473 | 2013 |
Impact of Bacillus Calmette-Guérin Moreau vaccine on lung remodeling in experimental asthma | 10.1016/j.resp.2013.07.025 | 2013 |
Bone marrow-derived mononuclear cells vs. mesenchymal stromal cells in experimental allergic asthma | 10.1016/j.resp.2013.03.014 | 2013 |
Effects of Mesenchymal Stem Cell Therapy on the Time Course of Pulmonary Remodeling Depend on the Etiology of Lung Injury in Mice | 10.1097/ccm.0b013e31828a663e | 2013 |
Regular and moderate exercise before experimental sepsis reduces the risk of lung and distal organ injury. | 10.1152/japplphysiol.01061.2011 | 2012 |
Hypertonic Stress Induces VEGF Production in Human Colon Cancer Cell Line Caco-2: Inhibitory Role of Autocrine PGE2 | 10.1371/journal.pone.0025193 | 2011 |
Eosinophils as a Novel Cell Source of Prostaglandin D2: Autocrine Role in Allergic Inflammation | 10.4049/jimmunol.1101806 | 2011 |
Bone marrow-derived mononuclear cell therapy in experimental pulmonary and extrapulmonary acute lung injury | 10.1097/CCM.0b013e3181e796d2 | 2010 |
Co-operative signalling through DP1 and DP2 prostanoid receptors is required to enhance leukotriene C4 synthesis induced by prostaglandin D2 in eosinophils | 10.1111/j.1476-5381.2010.01086.x | 2010 |
Cytosolic phospholipase A2-driven PGE2synthesis within unsaturated fatty acids-induced lipid bodies of epithelial cells? | 10.1016/j.bbalip.2009.01.003 | 2009 |
Leukotriene B4 mediates T lymphocyte migration in response to diverse stimuli | 10.1189/jlb.0809563 | 2009 |
Hypertonic environment elicits cyclooxygenase-2-driven prostaglandin E2 generation by colon cancer cells: Role of cytosolic phospholipase A2-? and kinase signaling pathways? | 10.1016/j.plefa.2009.11.005 | 2009 |
Prostaglandin E2-EP1 and EP2 receptor signaling promotes apical junctional complex disassembly of Caco-2 human colorectal cancer cells | 10.1186/1471-2121-9-63 | 2008 |
Cutting Edge: Prostaglandin D2 Enhances Leukotriene C4 Synthesis by Eosinophils during Allergic Inflammation: Synergistic In Vivo Role of Endogenous Eotaxin. | 2006 | |
Group V secretory phospholipase A2 amplifies the induction of cyclooxygenase 2 and delayed prostaglandin D2 generation in mouse bone marrow culture-derived mast cells in a strain-dependent manner | 10.1016/j.bbalip.2006.09.009 | 2006 |
Auto-antibodies in prostate cancer: Humoral immune response to antigenic determinants coded by the differentially expressed transcripts FLJ23438 and VAMP3 | 10.1002/pros.20439 | 2006 |
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats. | 10.1016/j.ejphar.2005.02.011 | 2005 |
A novel effect for annexin 1-derived peptide Ac2-26: reduction of allergic inflammation in the rat. | 10.1124/jpet.104.080473 | 2005 |
Role of secretory phospholipase A(2) in IL-6 and VEGF production by mast cells | 2005 | |
Role of cytosolic PLA(2) na kinase signaling pathways on PGE(2) generation by a colon cancer cell line | 2005 | |
Diabetes and Cancer: the effect of hyperglycemia in metastatic development | 2005 | |
Role of group V phospholipase A2 in zymozan-induced eicosanoid generation and vascular permeability revealed by targeted gene disruption | 10.1074/jbc.M313748200 | 2004 |
Role of group V phospholipase A(2) in zymosan-induced eicosanoidgeneration and vascular permeability revealed by targeted gene disruption | 2004 | |
Adoptive transfer of mast cells abolishes the inflammatory refractoriness to allergen in diabetic rats | 10.1159/000071489 | 2003 |
Phospholipase A2 | 10.1016/S0952-3278(03)00069-3 | 2003 |
Systemic anaphylaxis is prevented in alloxan-diabetic rats by a mechanism dependent on glucocorticoids | 10.1016/S0014-2999(03)01934-4 | 2003 |
Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids | 2002 | |
Inhibition of allergen-induced eosinophil migration by lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 | 2002 | |
Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells | 2002 | |
Enhanced serum glucocorticoid levels mediate the reductionof serosal mast cell numbers in diabetic rats | 10.1016/S0024-3205(01)01087-6 | 2001 |
Exogenous but not endogenous prostanoids regulate COX-2 induction in mouse mast cells | 2001 | |
Cyclooxygenase-2-derived prostaglandin E2 and lipoxin A4 accelerate resolution of allergic edema in Angiostrongylus costaricensis-infected rats: relationship with concurrent eosinophilia | 2000 | |
Cutting edge: lipoxin (LX) A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking. | 2000 | |
Mechanism underlying acute resident leukocyte disappearance induced by immunological and non-immunological stimuli in rats: evidence for a role for the coagulation system | 10.1007/s000110050650 | 2000 |
Differential regulation of cytokine-dependent COX-2 and IL-6 expression by PGE(2) and 15d-PGJ(2) in mouse mast cells | 2000 | |
Antigen-induced pleural eosinophilia is suppressed in diabetic rats: role of corticosteroid hormones | 10.1590/s0074-02761997000800031 | 1997 |
Anti-Allergic Properties of the Natural PAF Antagonist Yangambin | 10.1055/s-2006-957654 | 1997 |
Local Exposure To Salbutamol Or Bt2 Cyclic Amp Inhibits Pleural Exudation And Leukocyte Influx Caused By Antigen In Rats | 10.1016/0014-2999(95)00694-X | 1996 |
Selective Inhibition Of Phosphodiesterase Type Iv Suppresses The Chemotactic Responsiveness Of Rat Eosinophils In Vitro | 10.1016/0014-2999(96)00357-3 | 1996 |
Alloxan Diabetes Reduces Pleural Mast Cell Numbers and the Subsequent Eosinophil Influx Induced by Allergen in Sensitized Rats | 10.1159/000237343 | 1996 |
Salbutamol and dibutyryl cyclic AMP inhibit microvascular leakage and leucocyte infiltration caused by antigen in actively sensitized rats | 1994 | |
Suppression by cetirizine of pleurisy triggered by antigen in actively sensitized rats. | 10.1016/0014-2999(92)90811-H | 1992 |
Pharmacological Modulation of the Late Eosinophilia Induced by Antigen in Actively Sensitized Rats | 10.1159/000236211 | 1992 |
Eventos:
(1.92% eventos com DOI)
Titulo | DOI | Ano |
---|---|---|
EFFECTS OF GLUTAMINE THERAPY IN EXPERIMENTAL PULMONARY AND EXTRAPULMONARY ACUTE LUNG INJURY | 2011 | |
EFFECTS OF REGULAR AND MODERATE AEROBIC EXERCISE ON AIRWAY AND LUNG PARENCHYMA REMODELING IN A MURINE MODEL OF CHRONIC ALLERGIC ASTHMA | 2011 | |
LEUKOTRIENE B4/BLT1 MEDIATES γδ T LYMPHOCYTE MIGRATION DURING INFLAMMATION | 2011 | |
Secretory type group V PLA2: possible role in renal physiology | 2011 | |
Role of Prolactin and Glucocorticoid Receptor Interactions in the Thymus Atrophy Occurring During Experimental Trypanosoma Cruzi Infection | 2011 | |
Cooperative DP1- and CRTH2-activated signalling is required to elicit enhanced leukotriene C4 synthesis induced by prostaglandin D2 within eosinophils | 2010 | |
PHOSPHOLIPASE A2 GROUP V IN LEISHMANIASIS: ROLE IN IMMUNITY | 2010 | |
Eosinophils as novel cell source of prostaglandin D2: autocrine activity and allergy-driven synthesis | 2010 | |
LEUKOTRIENE B4 MEDIATES γδ T LYMPHOCYTE MIGRATION IN RESPONSE TO DIVERSE STIMULI | 2010 | |
IN VITRO-DIFFERENTIATED MOUSE EOSINOPHILS AS A NEW TOOL FOR THE STUDY OF EOSINOPHIL BIOLOGY. | 2010 | |
Glucose starvation induces melanogenesis in B16F10 MURINE MELANOMA CELLS through oxidative stress | 2010 | |
Glucose starvation induces melanogenesis in B16F10 in mouse melanoma cells through oxidative stress | 2010 | |
Glucose starvation induces melanogenesis in B16F10 mouse melanoma cells through oxidative stress | 2010 | |
Activation of PGD receptors, DP1 and CRTH2, elicits 2 complementary signaling that evokes LTC4 secretion from eosinophils | 2009 | |
Bradykinin activates human eosinophils: role of endogenous PGE2 in induction of lipid body biogenesis | 2009 | |
Human eosinophils synthesize PGD : autocrine function in eosinophil activation | 2009 | |
Leukotriene B4 mediates gamma delta T lymphocyte migration in response to diverse stimuli | 2009 | |
Cytosolic phospholipase A2-driven arachidonic acid mobilization within newly assembled lipid bodies of epithelial cells | 2008 | |
MIgração induzida por heme depende da via da 5-lipoxigenase | 2007 | |
PGD2 elicits differential release of pre-formed cytokines from eosinophils: cooperative signaling between DP and CRTH2 receptors | 2007 | |
Role of cytosolic PLA2 and kinase signaling pathways on PGE2 generation by a colon cancer cell line | 2006 | |
PGD2 controls LTC2 synthesis by eosinophils during allergic inflammation: synergistic role of endogenous eotaxin | 2006 | |
Modulation of lipid body in epithelial cells | 2006 | |
Estudo da Modulação de corpúsculos lipídicos em células epiteliais | 2006 | |
SECRETION OF CXC CHEMOKINE BY MACROPHAGES LINKS TLR2-DEPENDET SENSING OF Trypanosoma cruzi to MECHANISMS THAT STEER INNATE IMMUNITY VIA BRADYKININ RECEPTORS | 2006 | |
SECRETION OF CHEMOKINES BY MACROPHAGES LINKS TLR2-DEPENDENT SENSING OF Trypanosoma cruzi TO MECHANISMS THAT STEER INNATE IMMUNITY VIA BRADYKININ RECEPTORS | 2006 | |
Estudo da modulação de Corpúsculos lipídicos em Células epiteliais e endoteliais. | 2005 | |
Role of group V phospholipase A2 in eicosanoid generation revealed by gene disruption | 2004 | |
Role of secretory phospholipases A2 in IL-6 and VEGF production by mast cells | 2004 | |
Role of phospholipases A2 in COX-2 induction in colon cancer cell line Caco-2 | 2004 | |
Evaluating the prophylactic potential of the phtalimide derivative LASSBio 552 on allergen-evoked inflammation in rats | 2004 | |
Role of secretory phospholipases A2 in IL-6 production by mast cells and macrophages | 2004 | |
Papel de Fosfolipase A2 Secretória na Expressão de COX-2 e Produção de VEGF em Câncer de Cólon | 2003 | |
Papel de Fosfolipase A2 Secretória na Produção de IL-6 por Mastócitos Derivados de Medula Óssea | 2003 | |
Novel Phenoxi-phtalimid Acid Derivative LASSBIO 552 Caused a Selective Inhibition of Allergen-Evoked Eosinophil Recruitment in Sensitized Rats | 2003 | |
Phsopholipase A2 and the Regulation of Eicosanoid Biosynthesis in Mouse Mast Cells | 2001 | |
Lipoxin (LX)A4 and aspirin-triggered 15-epi-LXA4 block allergen-induced eosinophil trafficking in rats | 1999 | |
Cytosolic phospholipase A is essential for both the immediate and the delayed phases of eicosanoid generation in mouse bone marrow-derived mast cells | 10.1016/S0090-6980(99)90274-5 | 1999 |
Antigen-Induced Eosinophilia In Experimental Diabetes: Role Of Endogenous Corticosteroids And Mast Cells. | 1997 | |
Production And Distribution Of Eosinophils In Parasitic Infection By Agiostrogylus Costaricencis In Wistar Rats. | 1997 | |
Hyporesponsiveness Of Mast Cell Population In Experimental Diabetes: Involvement Of Endogenous Corticosteroids. | 1996 | |
Detection Of A Soluble Eosinophilopoietic Factor In Parasitic Infection By Angiostrongylus Costaricencis In Wistar Rats | 1996 | |
Reduction Of Mast Cell Population In Experimental Diabetes: Role Of Endogenous Corticosteroids | 1996 | |
Hyporesponsiveness Of Mast Cell Population In Experimental Diabetes: Involvement Of Endogenous Corticosteroids. | 1996 | |
Alloxan-Diabetes Reduces Pleural Mast Cell Numbers And Antigen-Induced Eosinophilia In Sensitised Rats: Role Of Insulin And Corticosteroids | 1996 | |
Selective Inhibition Of Phosphodiesterase Type Iv Suppresses The Chemotactic Responsiveness Of Rat Eosinophils In Vitro | 1996 | |
Efeito da Lignana Yangambina Sobre A Resposta Inflamatória Alérgica Pleural Em Ratos Ativamente Sensibilizados. | 1995 | |
Yangambina Inibe Trombocitopenia Induzida Por Antígeno Em Ratos Ativamente Sensibilizados: Evidência do Envolvimento de Paf. | 1995 | |
Insulin Modulatory Effect On Pleural Mast Cell Population In Alloxan-Diabetic Rats. | 1995 | |
Papel dos Mastócitos No Comprometimento da Resposta Pleural Alérgica Observada Em Ratos Diabéticos. | 1994 | |
Efeito de Inibidores Seletivos de Fosfodiesterases Sobre A Eosinofilia Pleural Alérgica Em Ratos: Interação Com Salbutamol. | 1994 | |
Effect Of Selective Phosphodiesterase Inhibitors On The Eosinophil Chemotaxis Induced By LTB4 In Vitro | 1994 |