Marcos Henrique Ferreira Sorgine

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Biologia Molecular e Biotecnologia

ORCID:

https://orcid.org/0000-0003-0003-4676


Formação:

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 1998 - 2002

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Mestrado | 1996 - 1998

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas | Graduação | 1993 - 1996

  • Escola Técnica Federal de Química

    Biotecnologia | Ensino Profissional de nível técnico | 1989 - 1992
Laboratórios:
Nuvens de Palavras:
Artigos:

(85.96% artigos com DOI)

Titulo DOI Ano
Wolbachia pipientis modulates metabolism and immunity during Aedes fluviatilis oogenesis 10.1016/j.ibmb.2022.103776 2022
Sexual Dimorphism in Immune Responses and Infection Resistance in Aedes aegypti and Other Hematophagous Insect Vectors 10.3389/fitd.2022.847109 2022
Aedes aegypti Infection With Trypanosomatid Strigomonas culicis Alters Midgut Redox Metabolism and Reduces Mosquito Reproductive Fitness 10.3389/fcimb.2021.732925 2021
Prostaglandins regulate humoral immune responses in Aedes aegypti 10.1371/journal.pntd.0008706 2020
Natural infection by the protozoan Leptomonas wallacei impacts the morphology, physiology, reproduction, and lifespan of the insect Oncopeltus fasciatus 10.1038/s41598-019-53678-1 2019
Increase in fatty acids and flotillins upon resveratrol treatment of human breast cancer cells 10.1038/s41598-019-50416-5 2019
Zika infection decreases Aedes aegypti locomotor activity but does not influence egg production or viability 10.1590/0074-02760180290 2018
Ticks as potential vectors of Mycobacterium leprae: Use of tick cell lines to culture the bacilli and generate transgenic strains 10.1371/journal.pntd.0007001 2018
The transcriptome of the mosquito Aedes fluviatilis (Diptera: Culicidae), and transcriptional changes associated with its native Wolbachia infection 10.1186/s12864-016-3441-4 2017
Microbiota activates IMD pathway and limits Sindbis infection in Aedes aegypti 10.1186/s13071-017-2040-9 2017
Catalase protects Aedes aegypti from oxidative stress and increases midgut infection prevalence of Dengue but not Zika 10.1371/journal.pntd.0005525 2017
Wolbachia and dengue virus infection in the mosquito Aedes fluviatilis (Diptera: Culicidae) 10.1371/journal.pone.0181678 2017
Hydrogen peroxide resistance in Strigomonas culicis : Effects on mitochondrial functionality and Aedes aegypti interaction 10.1016/j.freeradbiomed.2017.10.006 2017
Emerging role of lipid droplets in Aedes aegypti immune response against bacteria and Dengue virus 10.1038/srep19928 2016
Tyrosine Detoxification Is an Essential Trait in the Life History of Blood-Feeding Arthropods 10.1016/j.cub.2016.06.025 2016
Detection of human fecal contamination by nifH gene quantification of marine waters in the coastal beaches of Rio de Janeiro, Brazil 10.1007/s11356-016-7737-3 2016
Experimental Infection of Rhodnius prolixus (Hemiptera, Triatominae) with Mycobacterium leprae Indicates Potential for Leprosy Transmission 10.1371/journal.pone.0156037 2016
ATP Binding Cassette Transporter Mediates Both Heme and Pesticide Detoxification in Tick Midgut Cells 10.1371/journal.pone.0134779 2015
Heme Signaling Impacts Global Gene Expression, Immunity and Dengue Virus Infectivity in Aedes aegypti 10.1371/journal.pone.0135985 2015
Monitoring of the Parasite Load in the Digestive Tract of Rhodnius prolixus by Combined qPCR Analysis and Imaging Techniques Provides New Insights into the Trypanosome Life Cycle 10.1371/journal.pntd.0004186 2015
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection 10.1073/pnas.1506226112 2015
An Insight into the Transcriptome of the Digestive Tract of the Bloodsucking Bug, Rhodnius prolixus 10.1371/journal.pntd.0002594 2014
Molecular Analysis of Aedes aegypti Classical Protein Tyrosine Phosphatases Uncovers an Ortholog of Mammalian PTP-1B Implicated in the Control of Egg Production in Mosquitoes 10.1371/journal.pone.0104878 2014
Toll signals regulate dorsal-ventral patterning and anterior-posterior placement of the embryo in the hemipteran Rhodnius prolixus 10.1186/2041-9139-5-38 2014
Silencing of P-glycoprotein increases mortality in temephos-treated Aedes aegypti larvae 10.1111/imb.12052 2013
Ovarian Dual Oxidase (Duox) Activity is Essential for Insect Eggshell Hardening and Waterproofing 10.1074/jbc.m113.522201 2013
Validation of Aedes aegypti Aag-2 cells as a model for insect immune studies 10.1186/1756-3305-5-148 2012
Why do we need alternative tools to control mosquito-borne diseases in Latin America? 10.1590/S0074-02762012000600021 2012
The Dengue Vector Aedes aegypti Contains a Functional High Mobility Group Box 1 (HMGB1) Protein with a Unique Regulatory C-Terminus 10.1371/journal.pone.0040192 2012
Dengue Infection Increases the Locomotor Activity of Aedes aegypti Females 10.1371/journal.pone.0017690 2011
Blood Meal-Derived Heme Decreases ROS Levels in the Midgut of Aedes aegypti and Allows Proliferation of Intestinal Microbiota 10.1371/journal.ppat.1001320 2011
Calreticulin expression levels and endoplasmic reticulum during late oogenesis and early embryogenesis of Rhodnius prolixus Stahl 10.1007/s11033-010-0290-0 2011
Transcriptome and gene expression profile of ovarian follicle tissue of the triatomine bug Rhodnius prolixus 10.1016/j.ibmb.2011.06.004 2011
Heme-Oxygenases during Erythropoiesis in K562 and Human Bone Marrow Cells 10.1371/journal.pone.0021358 2011
Potential impact of a presumed increase in the biting activity of dengue-virus-infected Aedes aegypti (Diptera: Culicidae) females on virus transmission dynamics 2011
A real-time PCR procedure for detection of dengue virus serotypes 1, 2, and 3, and their quantitation in clinical and laboratory samples 10.1016/j.jviromet.2009.10.001 2010
Effect of GSK-3 activity, enzymatic inhibition and gene silencing by RNAi on tick oviposition and egg hatching 10.1017/s0031182010000284 2010
Blood-Feeding Induces Reversible Functional Changes in Flight Muscle Mitochondria of Aedes aegypti Mosquito 10.1371/journal.pone.0007854 2009
BYC, an atypical aspartic endopeptidase from Rhipicephalus (Boophilus) microplus eggs 10.1016/j.cbpb.2007.12.007 2008
An extraovarian aspartic protease accumulated in tick oocytes with vitellin-degradation activity 10.1016/j.cbpb.2008.08.008 2008
Calcium-regulated fusion of yolk granules is important for yolk degradation during early embryogenesis of Rhodnius prolixus Stahl. 10.1242/jeb.02652 2007
Biochemical properties of the major proteins from Rhodnius prolixus eggshell. 10.1016/j.ibmb.2007.07.010 2007
Purification and antigenicity of two recombinant forms of Boophilus microplus yolk pro-cathepsin expressed in inclusion bodies. 10.1016/j.pep.2005.07.009 2006
Adaptations against heme toxicity in blood-feeding arthropods. 10.1016/j.ibmb.2006.01.009 2006
Heparin-binding Sites in Granulocyte-Macrophage Colony-stimulating Factor: LOCALIZATION AND REGULATION BY HISTIDINE IONIZATION. 10.1074/jbc.M505314200 2005
Binding and storage of heme by vitellin from the cattle tick, Boophilus microplus 10.1016/S0965-1748(02)00162-5 2002
On the biosynthesis of Rhodnius prolixus heme-binding protein. 10.1016/s0965-1748(02)00074-7 2002
Crystallization and preliminary X-ray study of haem-binding protein from the bloodsucking insect 10.1107/s0907444901004437 2001
A heme-binding aspartic proteinase from the eggs of the hard tick Boophilus microplus. 10.1074/jbc.m005675200 2000
Characterization of Boophilus microplus heme-binding aspartic preoteinase (THAP). 2000
Synthesis of the heme-binding protein from follicle cells of Rhodnius prolixus. 2000
A heme-binding aspartic proteinase from the eggs of the hard tick Boophilus microplus 1999
Isolation of an aspartic proteinase precursor from the egg of a hard tick, Boophilus microplus 1998
A novel methodology for the investigation of intracellular proteolytic processing in intact cells 1998
Immunization of bovines with an aspartic porteinase precursor isolated from Boophilus microplus eggs 10.1016/S0165-2427(98)00194-9 1998
Physiologica role for hemozoin synthesis in Rhodnius prolixus. 1998
Cloning and Sequencing of Rhodnius prolixus heme-binding protein (RHBP). 1997
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Boophilus yolk cathepsin (BYC), an atypical aspartil peptidase from the hard tick B. microplus 2004
Development and evaluation of a reverse transcription Real-Time PCR assay for detection and quantication of all Dengue virus serotypes 2004
Digestion of hemoglobin in the midgut of Aedes aegypti 2004
Boophilus Yolk pro-Cathepsin cloning, expression and analysis of immunogenicity 2004
Heme, oxidation and enveloped virus. 2004
Analysis of Boophilus Yolk Cathepsin (BYC). 2003
Ungulate pregnancy specific protein is similar to Boophilus Yolk Cathepsin (BYC). 2003
Pro-oxidant effects of heme in vesicular stomatitis vírus (VSV). 2003
Molecular Analysis of the major protein composition of Rhodnius prolixus eggshell 2003
Purification of a digestive aspartyl proteinase from the hard tick Boophilus microplus. 2002
Cloning and expression of a heme-binding aspartic proteinase of Boophilus microplus. 2002
Synthesis and processing of Tick Heme-binding aspartic proteinase (THAP) 2002
Is Boophilus Yolk Cathepsin (BYC) related to bovine pregnancy specific proteins 2002
Pro-oxidant effects of heme in vesicular stomatitis vírus (VSV) 2002
Purification of a digestive acid endopeptidase from the hard-tick Boophilus microplus 2001
Cloning and gene expression of two major proteins of the Rhodnius prolixus eggshell 2001
The hard tick Boophilus microplys presents a protein similar to the protein associated glycoproteins of the ungullate mammals 2001
Heme-binding proteins in hematophagous insects. 2000
Further characterization of Boophilus microplus heme-binding aspartic preoteinase. 2000
A heme-binding aspartic proteinase from the eggs of the hard tick Boophilus microplus 1999
A heme-binding aspartic proteinase from the eggs of the hard tick Boophilus microplus 1999
Characterization of vitellin as a heme-binding protein in Boophilus microplus eggs 1998
Effect of the inoculation into Boophilus microplus of a monoclonal antibody against BYC 1998
Cattle immunity to Boophilus microplus infestation by vaccination with BYC 1998
Cloning and sequencing of a heme-binding protein of Rhodnius Prolixus. 1997
Purification and characterization of a new protease from the eggs of the hard tick Boophilus microplus and its possible heme-binding role. 1997
Kinetics of degradation of Bodipy-BSA in intact macrophages. 1996
Purification and partial characterization of Boophilus microplus vitellin and vitellogenin. 1995
A New Heme-Binding protein from the Egg of the Hard Tick Boophilus microplus. 1995
Uma Nova Proteína de Ligação de Heme do Carrapato Bovino Boophilus microplus. 1995
Identification of Heme-Binding Proteins from the Egg and Hemolymph of the Hard Tick Boophilus microplus. 1994
Purification and Partial Characterization of a Low Molecular Weight Protein From the Hard Tick Boophilus Microplus. 1994
Heme-Binding Protein Synthesis and its Uptake by the Oocytes of Rhodnius prolixus. 1993
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