Helena Maria Marcolla Araujo

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Ciências Biomédicas

Departamento:

Diretoria Adjunta de Pós-graduação/ICB

ORCID:

https://orcid.org/0000-0003-0371-9523


Formação:

  • Universidade da California Em San Diego

    | Pós-Doutorado | 1996 - 1999

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1988 - 1992

  • Universidade Federal do Rio Grande do Sul

    Ciências Biológicas (Bioquímica) | Mestrado | 1985 - 1988

  • Universidade de Brasília

    Bacharelado Em Ciencias Biologicas Biologia Molecu | Graduação | 1980 - 1985
Laboratórios:
Nuvens de Palavras:
Artigos:

(77.78% artigos com DOI)

Titulo DOI Ano
Boosting life sciences research in Brazil: building a case for a local Drosophila stock center 10.1590/1678-4685-gmb-2023-0202 2024
Gene Editing in the Chagas Disease Vector by Cas9-Mediated ReMOT Control 10.1089/crispr.2023.0076 2024
A pro-BMP function exerted by Rhodnius prolixus short gastrulation reveals great diversity in the role of BMP modulators during embryonic patterning 10.1098/rsob.230023 2023
Atypical strategies for cuticle pigmentation in the blood-feeding hemipteran Rhodnius prolixus 10.1093/genetics/iyac064 2022
Analysis of ovarian transcriptomes reveals thousands of novel genes in the insect vector Rhodnius prolixus 10.1038/s41598-021-81387-1 2021
Evolution of the dorsoventral axis in insects: the changing role of Bone Morphogenetic Proteins 10.1016/j.cois.2021.09.004 2021
A reaction-diffusion network model predicts a dual role of Cactus/IκB to regulate Dorsal/NFκB nuclear translocation in Drosophila 10.1371/journal.pcbi.1009040 2021
Multiple Roles of the Polycistronic Gene Tarsal-less/Mille-Pattes/Polished-Rice During Embryogenesis of the Kissing Bug Rhodnius prolixus 10.3389/fevo.2019.00379 2019
Transcriptomic and functional analyses of the piRNA pathway in the Chagas disease vector Rhodnius prolixus 10.1371/journal.pntd.0006760 2018
N-linked glycosylation restricts the function of short gastrulation to bind and shuttle BMPs 10.1242/dev.167338 2018
In Vivo Efficacy of Ellagic Acid against Candida albicans in a Drosophila melanogaster Infection Model 10.1128/aac.01716-18 2018
Translating genetic, biochemical and structural information to the calpain view of development 10.1016/j.mod.2018.07.011 2018
Genesis special issue: New models for arthropod research 10.1002/dvg.23037 2017
Rhodnius prolixus : From classical physiology to modern developmental biology 10.1002/dvg.22995 2017
A novel function for Cactus/IκB inhibitor to promote Dl nuclear localization and activity in the Drosophila embryo 10.1242/dev.145557 2017
Calpain A controls mitotic synchrony in the Drosophila blastoderm embryo 10.1016/j.mod.2016.05.005 2016
A conserved role for Calpains during myoblast fusion 10.1002/dvg.22870 2015
Genome of Rhodnius prolixus, an insect vector of Chagas disease, reveals unique adaptations to hematophagy and parasite infection 10.1073/pnas.1506226112 2015
Functional studies of TcRjl, a novel GTPase of Trypanosoma cruzi, reveals phenotypes related with MAPK activation during parasite differentiation and after heterologous expression in Drosophila model system 10.1016/j.bbrc.2015.09.110 2015
An Insight into the Transcriptome of the Digestive Tract of the Bloodsucking Bug, Rhodnius prolixus 10.1371/journal.pntd.0002594 2014
Chitin deposition on the embryonic cuticle of Rhodnius prolixus: the reduction of CHS transcripts by CHS-dsRNA injection in females affects chitin deposition and eclosion of the first instar nymph 10.1016/j.ibmb.2013.12.004 2014
Toll signals regulate dorsal-ventral patterning and anterior-posterior placement of the embryo in the hemipteran Rhodnius prolixus 10.1186/2041-9139-5-38 2014
Calpain A modulates Toll responses by limited Cactus/I B proteolysis 10.1091/mbc.e13-02-0113 2013
The embryogenesis of the Tick Rhipicephalus (Boophilus) microplus : The establishment of a new chelicerate model system 10.1002/dvg.22717 2013
Position matters: Variability in the spatial pattern of BMP modulators generates functional diversity 10.1002/dvg.20778 2011
aPS1bPS Integrin Receptors Regulate the Differential 10.1002/dvg.20579 2010
The Ca2+-dependent protease Calpain A regulates Cactus/IjB 10.1016/j.mod.2009.04.005 2009
Graded maternal short gastrulation protein contributes to embryonic dorsal¿ventral patterning by delayed induction 10.1016/j.ydbio.2006.04.453 2006
The maternal JAK/STAT pathway of Drosophila regulates embryonic dorsal-ventral patterning 10.1590/S0100-879X2004001200006 2004
Biosynthesis and metabolism of sulfated glycosaminoglycans during Drosophila melanogaster development 10.1093/glycob/cwh070 2004
Requirement of the roughest gene for differentiation and time of death of interommatidial cells during pupal stages of Drosophila compound eye development 10.1016/S0925-4773(03)00040-6 2003
Integrins modulate Sog activity in the Drosophila wing 10.1242/dev.00613 2003
and exert opposing maternal functions to modify Toll signaling and pattern the dorsoventral axis of the embryo 10.1242/dev.127.16.3631 2000
Blockage of 9-O-acetyl gangliosides induces microtubule depolymerization in growth cones and neurites 1997
Depolymerization Of Macrophage Microfilaments Prevents Induction And Inhibits Activity Of Nitric Oxide Synthase 1996
Endogenous phosphorylation of Tau protein in brain slices 1994
Characterization of PEA-15, a major substrate for protein kinase C in astrocytes. 10.1016/S0021-9258(18)53407-4 1993
PEA-15 a novel major astrocitic phosphoprotine. Identification of two phosphorylation sites 1993
Differential tau phosphorylation in cell culture and mouse brain slices 1992
Abnornal Proteins In The Cerebrospinal Fluid Of A Patient With Creutzfeldt-Jakob Disease Following Administration Of Human Pituitary Growth Hormone. 1992
Pituitary growth hormone and Creuzfeldt-Jacob disease 1991
Pituitary growth hormone and Creutzfeldt-Jakob disease. 10.1136/bmj.302.6785.1149 1991
Synaptosomal apirase in the hipotalamos of adult rats 1989
Mouse brain Tau proteins: Microheterogeneity and phosphorylation 1989
Ecto-apirase de fracao sinaptossomal de hipotalamo de rato 1986
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
STUDY OF THE DYNAMICS OF EMBRYONIC TRANSCRIPTION FACTOR GRADIENTS IN THE BEETLE TRIBOLIUM CASTANEUM 2019
QUANTITATIVE ASPECTS OF NF?B ACTIVITY IN Drosophila melanogaster INNATE IMMUNITY 2019
STUDY OF THE DYNAMICS OF EMBRYONIC TRANSCRIPTION FACTOR GRADIENTS IN THE BEETLE TRIBOLIUM CASTANEUM 2019
Evaluation of the potencial of application of cyclodextrin complexed with ellagic acid for the treatment of oral candidosis 2019
A surprising twist to insect dorsal-ventral patterning 2018
Establishing DNA regions and phenotypic markers for efficient genome engineering in the Chagas disease vector Rhodnius prolixus 2018
EXPLORANDO MARCADORES FENOTÍPICOS EM RHODNIUS PROLIXUS 2018
Respective contribution of the BMP and Toll pathways to axial patterning in the kissing bug Rhodnius prolixus 2017
Interacao entre as vias de Toll e BMP na padronizacao axial de R prolixus 2017
Interacao entre as vias de Toll e BMP na padronizacao axial de R prolixus 2017
Estabelecendo um protocolo para microinjeção em embriões de R prolixus 2017
Interplay between Toll and BMP pathways in R prolix us axial patterning 2017
Conservation and structural mechanisms involved in Toll pathway regulation by Calpain in insects 2017
Transcriptomic and functional analysis of the piRNA pathway in R prolix us 2017
Analise Funcional da via de BMP na padronizacao axial de R prolixus 2016
Analise funcional da via de BMPs em R prolixus 2016
The Toll pathway regulates dorsal-ventral patterning of the hemipteran Rhodnius prolixus 2015
QUANTITATIVE ASPECTS OF NFΚB ACTIVITY IN DROSOPHILA MELANOGASTER DV PATTERNING 2015
VEIN MORPHOGENESIS IN THE DROSOPHILA WING: BRIDGING CELL BEHAVIOR WITH VEIN SPECIFICATION 2015
Aálise funcional da via de BMP na padronização axial e Rhodnius prolixus 2015
Calpain A regulates NFkappaB function during embryogenesis and the immune response by Cactus proteolysis 2014
The role of the two promoter regions of hunchback in its RNA expression pattern in Drosophila melanogaster 2013
A mosca que pousou na sopa da cincia: uma proposta de divulgao 2012
Glycosylation processes regulate BMP pathway during Drosophila melanogaster developmemt 2012
The role of the maternal Dpp/BMP pathway on the regulation of RNA levels in the early Drosophila melanogaster embryo 2012
A via de Dpp/BMP pode atuar na degradação de RNAm maternais em embriões de Drosophila melanogaster? 2012
Atividade Histona Desacetilase é necessária para a morfogênese de tecidos epiteliais polarizados 2012
Functional analysis of Rhodnius prolixus DV patterning 2012
Are Calpains involved in Cactus/IkappaB degradation during muscle formation in Drosophila melanogaster and chick embryonic muscles? 2012
Glycosylation Processes Modulate BMP Pathway During Drosophila melanogaster Development 2012
Unrevealing the role of maternal Dpp/BMP pathway in the early embryo os Drosophila melanogaster 2011
The impact of the glycosylation processes on the activities of Sog and Dpp during Drosophila melanogaster development 2011
O impacto dos processos de glicosilação sobre a atividade de Sog e Dpp durante o desenvolvimento de Drosophila melanogaster. 2011
Influência da via de Dpp/BMP na estabilidade de RNAm maternais no embrião de Drosophila melanogaster 2011
Caracterização da atividade Histona Desacetilase (HDAC) durante o desenvolvimento embrionário de Drosophila melanogaster. 2011
A via de Dpp/BMP na formação dos territórios do eixo Dorso-ventral de Drosophila melanogaster 2010
Avaliação de BMPs e CHORDIN como Marcadores Tumorias em Glioblastomas Humanos 2010
Dpp/BMP pathway regulates maternal mRNA levels in the early embryo to pattern the dorsoventral axis in Drosophila melanogaster 2010
Establishing a protocol for in situ hybridization in embryos of the hematophagous insect Rhodnius prolixus. 2010
Maternal Dpp/BMP pathway regulates post-transcriptional processes in the early embryo to pattern the dorsoventral axis in Drosophila melanogaster 2010
Multiple Modes for the regulation of Short gastrulation and Dpp activity 2010
A Curious interactions between Cactus and the Ca-dependent protease Calpain A 2009
DIFFERENTIAL DISTRIBUTION OF SOG FRAGMENTS REGULATES DPP SIGNALLING IN POLARIZED EPITHELIA OF DROSOPHILA MELANOGASTER 2009
MATERNAL DPP/BMP PATHWAY REGULATES CALPAIN A ACTIVITY TO PATTERN THE EMBRYONIC DORSAL-VENTRAL AXIS IN DROSOPHILA MELANOGASTER. 2009
GENERATION OF MUTANTS FOR THE CALPAIN A LOCUS IN DROSOPHILA MELANOGASTER USING P ELEMENT AS MUTAGENIC AGENT 2009
35. STUDY OF PUTATIVE MALE FERTILITY GENES LOCATED ON THE Y CHROMOSOME OF D. MELANOGASTER USING DOUBLE-STRANDED RNA INTERFERENCE TECHNOLOGY (RNAi) 2009
The Ca-dependent protease CalpA modulates embryonic DV patterning 2008
Spatial distribution of Sog in polarized epithelia during Drosophila development 2008
Generation of mutants for the calpain locus of D. melanogaster 2008
Use of RNAi for knockdown of putative male fertility genes located on the Y chromosome 2008
A multiplex in situ approach tp define the precise contribution of the maternal BMP pathway in dorsal-ventral patterning of the early Drosophila embryo 2007
Delayed effect of maternal BMP on establishment of the embryonic DV axis 2006
Maternal short gastrulation and decapentaplegic contribute to pattern the Drosophila DV axis by delayed induction 2005
Maternal Dpp signals through the thick veins receptor to alter the embryonic DV axis of Drosophila 2005
Establishment of Calpain mutants to study the calcium dependent degradation of cactus in the Drsosophila embryo 2005
Clonal analysis in follicle cells indicates that integrins play a role during DV axis formation of Drosophila embryos 2005
Maternal Sog fragments establish assymetry in BMP signallind during embryogenesis 2004
Generation of CalpA mutants and their effect on Drosophila embryogenesis 2004
Integrins modulate Sog activity during Drosophila development 2003
Do calcium-dependent processes mediate DV patterning signals in the Drosophila pre-blastoderm embryo? 2003
The Jak-Stat pathway interacts with maternal dpp signaling to modify the embryonic DV axis of Drosophila melanogaster 2003
Analysis of an interaction between sog and integrin genes during oogenesis 2003
Glucosaminoglycans during the development of Drosophila melanogaster: evidence for the transfer of chondroitin sulfate and heparan sulfate from adult female to the larva 2003
Short gastrulation produced by follicle cells during Drsoophila oogenesis functions through delayed induction to pattern the early embryo 2003
Sog protein is differentially distributed between intracellular domains of the dorsal and ventral wing epithelium 2003
Do Calcium dependent processes mediate dorsal-ventral patterning signals in the Drosophila pre-blastoderm embryo? 2003
Contribution of Sog/Chordin abd Dpp/BMP4 to the dorso-ventral patterning of the embryonic neuroectoderm 2003
Sog and integrins interact during wing vein development 2002
Expression of radiolabeled glycosaminoglycans in D. melanogaster after metabolic incorporation with 35S-sulfate 2002
short gastrulation interacts with integrins during wing vein development 2001
Are abbuting territories of Sog and Dpp sufficient to pertition the neuroectoderm into the three rows giving rise to neuroblasts? 2001
Characterization of a Novel Dominant Allele of the Rst/IrreC gene shows its requirement for pigment cell fate determination in the Drosophila retina 2001
Analysis of engrailed mutants that specifically disrupt the embryonic PNS and CNS development 2000
sog and dpp function antagonistically during Drosophila oogenesis to modify Toll signalling and pattern the embryonic dorso-ventral axis 1999
New alleles of engrailed reveal its requirement fro the formation of axonal commissures and chordotonal organs in Drosophila melanogaster 1999
Generation of new engrailed alleles with neural functions in Drosophila melanogaster 1999
Maternal sog and dpp pattern the embryonic dorsal-ventral axis by modifying the Dorsal gradient 1998
Final steps in ommatidial assembly. Characterization of a novel dominant allele of the locus irrec-rst 1996
Colapso do cone de crescimento induzido pelo mAb JONES em diferentes substratos de adesao 1996
Bloquieo de gangliosideos 9-O-acetilados produzem mudancas no citoesqueleto de celulas gliais 1996
Cytoskeletal dynamics in growth cone retraction induced by the mAb JONES 1995
O gangliosideo 9-O-acetil GD3 modula interacoes do neuronio com a matriz extracelular 1995
Expression of PEA-15 in astrocytic cell lines 1995
Growth inhibition and PEA-15 expression in cell lineages 1995
Dissassembly of microfilaments inhibits induction and activity of nitric oxide sythase 1995
Seleção de Mutantes Morfológicos em 3 linhagens de Metarhizium anisopliae 1983
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