Flavia Carvalho Alcantara Gomes
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Ciências Biomédicas
Departamento:
Instituto de Ciências Biomédicas/ICB
Formação:
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Doutorado | 1994 - 1999
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Mestrado | 1991 - 1994
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Universidade do Estado do Rio de Janeiro
Ciências Biológicas | Graduação | 1987 - 1991
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:
(85.23% artigos com DOI)
Titulo | DOI | Ano |
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Histone deacetylase inhibition mitigates cognitive deficits and astrocyte dysfunction induced by amyloid-β (Aβ) oligomers | 10.1111/bph.16439 | 2024 |
Age-associated upregulation of glutamate transporters and glutamine synthetase in mouse and human astrocytes | 10.1177/17590914231157974/ | 2023 |
Central nervous system demyelinating diseases: glial cells at the hub of pathology | 10.3389/fimmu.2023.1135540 | 2023 |
Synaptic pathology in multiple sclerosis: a role for Nogo-A signaling in astrocytes? | 10.4103/1673-5374.340407 | 2022 |
Contribution of Müller cells in the diabetic retinopathy development: focus on oxidative stress and inflammation | 10.3390/antiox11040617 | 2022 |
The flavonol quercitrin hinders GSK3 activity and potentiates the Wnt/β-catenin signaling pathway | 10.3390/ijms232012078 | 2022 |
Ethanol Gestational Exposure Impairs Vascular Development and Endothelial Potential to Control BBB-Associated Astrocyte Function in the Developing Cerebral Cortex | 10.1007/s12035-020-02214-8 | 2021 |
Astrocytes as a target for |
10.1002/glia.23971 | 2021 |
Loss of lamin-B1 and defective nuclear morphology are hallmarks of astrocyte senescence in vitro and in the aging human hippocampus | 10.1111/acel.13521 | 2021 |
Astrocyte glutamate transporters are increased in an early sporadic model of synucleinopathy | 10.1016/j.neuint.2020.104758 | 2020 |
Cryopreserved astrocytes maintain biological properties: support of neuronal survival and differentiation. | 10.1016/j.jneumeth.2020.108806 | 2020 |
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Glial Cells: insights and perspectives | 10.1016/j.bbih.2020.100127 | 2020 |
Astrocyte heterogeneity: impact to brain aging and disease | 10.3389/fnagi.2019.00059 | 2019 |
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice | 10.1038/s41419-019-1529-x | 2019 |
α-synuclein oligomers enhance astrocyte-induced synapse formation through |
10.1111/jnc.14710 | 2019 |
Detrimental Effects of HMGB-1 Require Microglial-Astroglial Interaction: Implications for the Status Epilepticus -Induced Neuroinflammation | 10.3389/fncel.2019.00380 | 2019 |
The Role of Astrocytes in the Development of the Cerebellum | 10.1007/s12311-019-01046-0 | 2019 |
Radial glia-Endothelial cells bidirectional interactions control vascular maturation and astrocyte differentiation: impact for blood brain barrier formation | 10.2174/1567202616666191014120156 | 2019 |
Astrocytes and the TGF-β1 Pathway in the Healthy and Diseased Brain: a Double-Edged Sword | 10.1007/s12035-018-1396-y | 2018 |
10.1 STEM CELL-DERIVED IN VITRO MODELS FOR DEPICTING THE ROLE OF GLIA IN SCHIZOPHRENIA FROM A PROTEOMIC PERSPECTIVE | 10.1093/schbul/sby014.034 | 2018 |
Interaction of Aβ Oligomers with Neurexin 2α and Neuroligin 1 Mediates Synapse Damage and Memory Loss in Mice | 10.1074/jbc.m116.761189 | 2017 |
Derivation of Functional Human Astrocytes from Cerebral Organoids | 10.1038/srep45091 | 2017 |
Radial Glia Cells Control Angiogenesis in the Developing Cerebral Cortex Through TGF-β1 Signaling | 10.1007/s12035-017-0557-8 | 2017 |
Flavonoid Hesperidin Induces Synapse Formation and Improves Memory Performance through the Astrocytic TGF-β1 | 10.3389/fnagi.2017.00184 | 2017 |
Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinsons disease-like symptoms in mice | 10.1016/j.bbr.2017.06.047 | 2017 |
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model | 10.1523/jneurosci.3351-16.2017 | 2017 |
TGF-β1/SMADs signaling pathway activation protects intestinal epithelium from Clostridium difficile toxin A-induced damage | 10.1128/iai.00430-17 | 2017 |
Neuroprotective astrocyte-derived insulin/IGF-1 stimulate endocytic processing and extracellular release of neuron-bound Ab oligomers | 10.1091/mbc.E17-06-0416 | 2017 |
Inflammatory demyelination alters subcortical visual circuits | 10.1186/s12974-017-0936-0 | 2017 |
Heterogeneity in Synaptogenic Profile of Astrocytes from Different Brain Regions | 10.1007/s12035-016-0343-z | 2017 |
Functions of flavonoids in the central nervous system: astrocytes as targets for natural compounds | 10.1016/j.neuint.2016.01.009 | 2016 |
Effects of transforming growth factor beta 1 in cerebellar development: role in synapse formation. | 10.3389/fncel.2016.00104 | 2016 |
Na/K-ATPase as a target for anticancer drugs: studies with perillyl alcohol | 10.1186/s12943-015-0374-5 | 2015 |
Activated Microglia-Induced Deficits in Excitatory Synapses Through IL-1β: Implications for Cognitive Impairment in Sepsis | 10.1007/s12035-014-8868-5 | 2015 |
Thyroid Hormone and Astroglia: Endocrine Control of the Neural Environment | 10.1111/jne.12283 | 2015 |
Astrocytic control of neural circuit formation: highlights on TGF-beta signaling | 10.1016/j.neuint.2014.07.008 | 2014 |
Astrocyte transforming growth factor beta 1 promotes inhibitory synapse formation via CaM kinase II signaling | 10.1002/glia.22713 | 2014 |
LPA-primed astrocytes induce axonal outgrowth of cortical progenitors by activating PKA signaling pathways and modulating extracellular matrix proteins | 10.3389/fncel.2014.00296 | 2014 |
TGF-β1 promotes cerebral cortex radial glia-astrocyte differentiation in vivo | 10.3389/fncel.2014.00393 | 2014 |
Lycopene and Beta-Carotene Induce Growth Inhibition and Proapoptotic Effects on ACTH-Secreting Pituitary Adenoma Cells | 10.1371/journal.pone.0062773 | 2013 |
Thyroid hormone treated astrocytes induce maturation of cerebral cortical neurons through modulation of proteoglycan levels | 10.3389/fncel.2013.00125 | 2013 |
Avaliação da proteína acídica fibrilar glial como marcador da injúria por isquemia-reperfusão hepática | 10.1590/s0100-69912013000300009 | 2013 |
Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis | 10.1038/cddis.2013.325 | 2013 |
Activation of MAPK/PI3K/SMAD Pathways by TGF-ß Controls Differentiation of Radial Glia into Astrocytes in vitro | 10.1159/000338108 | 2012 |
Effects of the flavonoid hesperidin in cerebral cortical progenitors in vitro: indirect action through astrocytes | 10.1016/j.ijdevneu.2012.01.008 | 2012 |
Sphingosine 1-phosphate-primed astrocytes enhance differentiation of neuronal progenitor cells | 10.1002/jnr.23076 | 2012 |
The flavonoids hesperidin and rutin promote neural crest cell survival | 10.1007/s00441-012-1472-y | 2012 |
Neuron¿Astroglial Interactions in Cell-Fate Commitment and Maturation in the Central Nervous System | 10.1007/s11064-012-0798-x | 2012 |
Astrocyte-induced Synaptogenesis Is Mediated by Transforming Growth Factor Signaling through Modulation of D-Serine Levels in Cerebral Cortex Neurons | 10.1074/jbc.m112.380824 | 2012 |
Thyroid hormone induces cerebellar neuronal migration and Bergmann glia differentiation through epidermal growth factor/mitogen-activated protein kinase pathway | 10.1111/j.1460-9568.2010.07490.x | 2011 |
Estradiol modulates TGF-?1 expression and its signaling pathway in thyroid stromal cells | 10.1016/j.mce.2011.02.001 | 2011 |
Hesperidin, a Flavone Glycoside, as Mediator of Neuronal Survival | 10.1007/s11064-011-0493-3 | 2011 |
Neuron¿glia signaling: Implications for astrocyte differentiation and synapse formation | 10.1016/j.lfs.2011.04.005 | 2011 |
Astrocytes treated by lysophosphatidic acid induce axonal outgrowth of cortical progenitors through extracellular matrix protein and epidermal growth factor signaling pathway. | 10.1111/j.1471-4159.2011.07421.x | 2011 |
Thyroid hormone receptor ? mutation causes severe impairment of cerebellar development | 10.1016/j.mcn.2010.02.004 | 2010 |
Flavonoids and Astrocytes Crosstalking: Implications for Brain Development and Pathology | 10.1007/s11064-010-0144-0 | 2010 |
Cognitive Dysfunction Is Sustained after Rescue Therapy in Experimental Cerebral Malaria, and Is Reduced by Additive Antioxidant Therapy | 10.1371/journal.ppat.1000963 | 2010 |
Effect of thyroid hormone depletion on cultured murine cerebral cortex astrocytes | 10.1016/j.neulet.2009.10.001 | 2009 |
Effects of the flavonoid casticin from Brazilian Croton betulaster in cerebral cortical progenitors in vitro: Direct and indirect action through astrocytes | 10.1002/jnr.22218 | 2009 |
PEMF fails to enhance nerve regeneration after sciatic nerve crush lesion | 10.1111/j.1529-8027.2009.00240.x | 2009 |
Glutamate activates GFAP gene promoter from cultured astrocytes through TGF-1 pathways | 10.1111/j.1471-4159.2008.05428.x | 2008 |
LPA receptor-dependent secondary effects via astrocytes promote neuronal differentiation. * F.GOMES E J.CHUN SÃO AUTORES CORRESPONDENTES. | 10.1074/jbc.m707758200 | 2008 |
TGF-b1/SMAD SIGNALING INDUCES ASTROCYTE FATE COMMITMENT IN VITRO: IMPLICATIONS FOR RADIAL GLIA DEVELOPMENT | 10.1002/glia.20522 | 2007 |
Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer´s disease | 2007 | |
Chacacterization of TGF-b1 type II receptor expression in cultured cortical astrocytes | 10.1290/0602013.1 | 2006 |
Proliferation of cerebellar neurons induced by astrocytes treated by thyroid hormone is mediated by a cooperation between cell-contact and soluble factors and involves the EGF-PKA pathway | 10.1002/jnr.20463 | 2005 |
Emerging roles for TGFb1 in nervous system development | 10.1016/j.ijdevneu.2005.04.001 | 2005 |
Neuritogenesis and neuronal differentation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound | 2005 | |
GFAP gene from astrocytes from distinct brain regions is distinctly modulated by TGF-b1. | 10.1111/j.1460-9568.2004.03249.x | 2004 |
Sialic acid residues on astrocytes regulate neuritogenesis by controlling the assembly of laminin matrices | 10.1242/jcs.01276 | 2004 |
Structure of laminin substrate modulates cellular signaling for neuritogenesis | 10.1242/jcs.00173 | 2002 |
Neuritogenesis induced by thyroid hormone treated astrocytes is mediated by epidermal growth factor/mitogen-activated protein kinase-phosphatidylinositol 3-kinase pathways and involves modulation of extracellular matrix proteins. | 10.1074/jbc.M209284200 | 2002 |
Differences in the activation of the GFAP gene promoter by prion and virus infections | 10.1016/S0169-328X(02)00547-8 | 2002 |
Neuron-glia interaction effects on GFAP gene: a novel role for transforming growth factor-b1 | 10.1046/j.1460-9568.2002.02283.x | 2002 |
Thyroid hormone role in nervous system morphogenesis | 2001 | |
Cross-talk between neurons and glia: highlights on soluble factors | 10.1590/s0100-879x2001000500008 | 2001 |
Modulation of GFAP Gene Promoter by neurons during development | 2000 | |
Glial Fibrillary Acidic Protein: Modulation By Growth Factors And Its Implication In Astrocytes Differentiation | 1999 | |
Neurons Induce GFAP Gene Promoter of Cultured Astrocytes from Transgenic Mice | 1999 | |
Regulatory Roles Of Maps In Neuronal Morphogenesis. Involvement Of The Extracellular Matrix | 1999 | |
Cerebellar Astrocytes Treatd By Thyroid Hormone Modulate Neuronal Proliferation | 1999 | |
Cerebellar astrocytes treated by thyroid hormone modulate neuronal proliferation | 10.1002/(sici)1098-1136(19990201)25:3<247::aid-glia5>3.0.co;2-2 | 1999 |
Neurons induce GFAP gene promoter of cultured astrocytes from transgenic mice | 10.1002/(sici)1098-1136(199904)26:2<97::aid-glia1>3.0.co;2-z | 1999 |
Thyroid Hormone Acting On Astrocytes In Culture | 1998 | |
Thyroid Hormone Action on Astroglial Cells From Distinct Brain Regions During Development | 1998 | |
Effects of triiodothyronine on astrocyte differention | 1996 | |
Leishmania Amazonensis: Multidrug Resistance In Vinblastine Resistant Promastigotes Is Associated With Rhodamine 123 Efflux, Dna Amplication And Rna Overexpression Of A Leishmania Mdr1 Gene | 1995 | |
Characterization of multidrug resistance genes in Leishmania amazonensis | 1992 |
Eventos:
(0.00% eventos com DOI)