Elvira Maria Saraiva
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Microbiologia
Departamento:
Departamento de Imunologia/IM
Formação:
-
National Institute of Child Health and Human Development
| Pós-Doutorado | 2002 - 2002
-
National Institutes Of Health Laboratory Of Parasitic Diseases
| Pós-Doutorado | 1992 - 1994
-
Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Doutorado | 1985 - 1991
-
Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Mestrado | 1978 - 1982
-
Universidade do Estado do Rio de Janeiro
Ciências Biológicas Modalidade Médica | Graduação | 1974 - 1977
Laboratórios:
Nuvens de Palavras:
Artigos:
(91.06% artigos com DOI)
Titulo | DOI | Ano |
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Resveratrol prevents the release of neutrophil extracellular traps (NETs) by controlling hydrogen peroxide levels and nuclear elastase migration | 10.1038/s41598-024-59854-2 | 2024 |
Leishmania infantum Axenic Amastigotes Induce Human Neutrophil Extracellular Traps and Resist NET-Mediated Killing | 10.3390/tropicalmed8070336 | 2023 |
Peripheral nervous system is injured by neutrophil extracellular traps (NETs) elicited by nonstructural (NS) protein-1 from Zika virus | 10.1096/fj.202201904R. | 2023 |
Chick heterophils release DNA extracellular traps (DETs) in vitro and in vivo upon Aspergillus fumigatus conidia exposure. | 10.1016/j.micinf.2023.105261 | 2023 |
Human neutrophil extracellular traps do not impair in vitro Toxoplasma gondii infection | 10.3389/fimmu.2023.1282278 | 2023 |
Acanthamoeba castellanii trophozoites escape killing by neutrophil extracellular traps using their 3--nucleotidase/nuclease activity | 10.1016/j.ejop.2023.126032 | 2023 |
Protective effect of methyl gallate on murine antigen-induced arthritis by inhibiting inflammatory process and bone erosion | 10.1007/s10787-021-00922-8 | 2022 |
Laminin Triggers Neutrophil Extracellular Traps (NETs) and Modulates NET Release Induced by Leishmania amazonensis | 10.3390/biomedicines10030521 | 2022 |
Leishmania infantum Defective in Lipophosphoglycan Biosynthesis Interferes With Activation of Human Neutrophils | 10.3389/fcimb.2022.788196 | 2022 |
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts | 10.3389/fimmu.2022.820131 | 2022 |
Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation | 10.3389/fimmu.2021.651740 | 2021 |
Leishmanicidal effect of 1,3,4-thiadiazolium mesoionic salts on Leishmania amazonensis in vitro | 10.1016/j.parint.2021.102342 | 2021 |
Leishmania Parasites Drive PD-L1 Expression in Mice and Human Neutrophils With Suppressor Capacity | 10.3389/fimmu.2021.598943 | 2021 |
Endocytosis and Exocytosis in Leishmania amazonensis Are Modulated by Bromoenol Lactone | 10.3389/fcimb.2020.00039 | 2020 |
Neutrophil extracellular trap-enriched supernatants carry microRNAs able to modulate TNF-α production by macrophages | 10.1038/s41598-020-59486-2 | 2020 |
In vitro leishmanicidal activity of monoterpenes present in two species of Protium (Burseraceae) on Leishmania amazonensis | 10.1016/j.jep.2020.112981 | 2020 |
DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis | 10.3389/fcimb.2020.00247 | 2020 |
CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes | 10.1371/journal.ppat.1008230 | 2020 |
Extracellular Traps Released by Neutrophils from Cats are Detrimental to Toxoplasma gondii Infectivity | 10.3390/microorganisms8111628 | 2020 |
Neutrophil extracellular traps from healthy donors and HIV-1-infected individuals restrict HIV-1 production in macrophages | 10.1038/s41598-020-75357-2 | 2020 |
Cloning, expression and purification of 3'-nucleotidase/nuclease, an enzyme responsible for the Leishmania escape from neutrophil extracellular traps | 10.1016/j.molbiopara.2019.02.004 | 2019 |
Neutrophil properties in healthy and Leishmania infantum-naturally infected dogs | 10.1038/s41598-019-42687-9 | 2019 |
Glutamine Therapy Reduces Inflammation and Extracellular Trap Release in Experimental Acute Respiratory Distress Syndrome of Pulmonary Origin | 10.3390/nu11040831 | 2019 |
Neutrophil extracellular traps contribute to the pathogenesis of leprosy type 2 reactions | 10.1371/journal.pntd.0007368 | 2019 |
The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy | 10.1371/journal.pntd.0007146 | 2019 |
Inflammatory profiling of patients with familial amyloid polyneuropathy | 10.1186/s12883-019-1369-4 | 2019 |
Immunotherapy using anti-PD-1 and anti-PD-L1 in Leishmania amazonensis-infected BALB/c mice reduce parasite load | 10.1038/s41598-019-56336-8 | 2019 |
Unexpected Rearrangement and Aromatization on Dehydration Reaction of the Bioactive Diterpenequinone 7α-Hydroxyroyleanone | 10.21577/0103-5053.20190223 | 2019 |
The in vitro antileishmanial activity of essential oil from Aloysia gratissima and guaiol, its major sesquiterpene against Leishmania amazonensis | 10.1017/S0031182017002335 | 2018 |
DNA extracellular traps are part of the immune repertoire of Periplaneta americana | 10.1016/j.dci.2018.01.012 | 2018 |
Respiratory Syncytial Virus induces the classical ROS-dependent NETosis through PAD-4 and necroptosis pathways activation | 10.1038/s41598-018-32576-y | 2018 |
Anti-Leishmania amazonensis activity of Serjania lethalis A. St.-Hil | 10.1016/j.parint.2016.10.018 | 2017 |
Leishmanicidal activity of the alkaloid-rich fraction from Guatteria latifolia | 10.1016/j.exppara.2016.12.014 | 2017 |
Neutrophil Extracellular Traps Reprogram IL-4/GM-CSF-Induced Monocyte Differentiation to Anti-inflammatory Macrophages | 10.3389/fimmu.2017.00523 | 2017 |
Molecular signatures of neutrophil extracellular traps in human visceral leishmaniasis | 10.1186/s13071-017-2222-5 | 2017 |
Tumor-Derived Exosomes Induce the Formation of Neutrophil Extracellular Traps: Implications For The Establishment of Cancer-Associated Thrombosis | 10.1038/s41598-017-06893-7 | 2017 |
Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives | 10.1248/cpb.c17-00293 | 2017 |
Oleanolic acid (OA) as an antileishmanial agent: Biological evaluation and in silico mechanistic insights | 10.1016/j.parint.2016.01.001 | 2016 |
The site of the bite: Leishmania interaction with macrophages, neutrophils and the extracellular matrix in the dermis | 10.1186/s13071-016-1540-3 | 2016 |
Neutrophil extracellular traps release induced by Leishmania: role of PI3Kgamma, ERK, PI3Kdelta, PKC, and [Ca2+]. | 10.1189/jlb.4A0615-261RR | 2016 |
Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection | 10.1371/journal.pntd.0004848 | 2016 |
The Brown Alga Stypopodium zonale (Dictyotaceae): A Potential Source of Anti-Leishmania Drugs | 10.3390/md14090163 | 2016 |
Capsular polysaccharides from Cryptococcus neoformans modulate production of neutrophil extracellular traps (NETs) by human neutrophils | 10.1038/srep08008 | 2015 |
Are Neutrophil Extracellular Traps Playing a Role in the Parasite Control in Active American Tegumentary Leishmaniasis Lesions? | 10.1371/journal.pone.0133063 | 2015 |
Leishmanicidal Effect of Synthetic trans-Resveratrol Analogs | 10.1371/journal.pone.0141778 | 2015 |
A metabolic shift towards pentose phosphate pathway is necessary for amyloid fibril- and phorbol 12-myristate 13-acetate -induced neutrophil extracellular trap (NET) formation | 10.1074/jbc.m115.640094 | 2015 |
Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites | 10.1038/srep18302 | 2015 |
HIV-1 Tat protein enhances the intracellular growth of Leishmania amazonensis via the ds-RNA induced protein PKR | 10.1038/srep16777 | 2015 |
3'-Nucleotidase/Nuclease Activity Allows Leishmania Parasites To Escape Killing by Neutrophil Extracellular Traps | 10.1128/iai.01232-13 | 2014 |
Resveratrol is active against Leishmania amazonensis: in vitro effect of its association with amphotericin B. | 10.1128/AAC.00093-14 | 2014 |
Warifteine, an Alkaloid Purified from Cissampelos sympodialis, Inhibits Neutrophil Migration In Vitro and In Vivo | 10.1155/2014/752923 | 2014 |
IL-27 enhances Leishmania amazonensis infection via ds-RNA dependent kinase (PKR) and IL-10 signaling | 10.1016/j.imbio.2014.11.006 | 2014 |
The presence of a symbiotic bacterium in Strigomonas culicis is related to differential ecto-phosphatase activity and influences the mosquito-protozoa interaction | 10.1016/j.ijpara.2013.02.005 | 2013 |
Different secreted phosphatase activities in | 10.1111/1574-6968.12080 | 2013 |
Trans-β-Caryophyllene: An Effective Antileishmanial Compound Found in Commercial Copaiba Oil (Copaifera spp.) | 10.1155/2013/761323 | 2013 |
Phosphatidylserine Exposure and Surface Sugars in Two Leishmania (Viannia) braziliensis Strains Involved in Cutaneous and Mucocutaneous Leishmaniasis | 10.1093/infdis/jis689 | 2013 |
Leishmania amazonensis exhibits phosphatidylserine-dependent procoagulant activity, a process that is counteracted by sandfly saliva | 10.1590/0074-0276108062013002 | 2013 |
ETosis: A Microbicidal Mechanism beyond Cell Death | 10.1155/2012/929743 | 2012 |
Maxadilan, the Lutzomyia longipalpis vasodilator, drives plasma leakage via PAC1â¿¿CXCR1/2-pathway | 10.1016/j.mvr.2011.10.003 | 2012 |
LDL uptake by Leishmania amazonensis: Involvement of membrane lipid microdomains | 10.1016/j.exppara.2012.02.014 | 2012 |
Amyloid Fibrils Trigger the Release of Neutrophil Extracellular Traps (NETs), Causing Fibril Fragmentation by NET-associated Elastase | 10.1074/jbc.M112.369942 | 2012 |
Evidence That a Laminin-Like Insect Protein Mediates Early Events in the Interaction of a Phytoparasite with Its Vector's Salivary Gland | 10.1371/journal.pone.0048170 | 2012 |
Dolabelladienetriol, a Compound from Dictyota pfaffii Algae, Inhibits the Infection by Leishmania amazonensis | 10.1371/journal.pntd.0001787 | 2012 |
Leishmania chagasi: An ecto-3¿-nucleotidase activity modulated by inorganic phosphate and its possible involvement in parasite¿macrophage interaction | 10.1016/j.exppara.2010.11.003 | 2011 |
Leishmanicidal effects of piperine, its derivatives, and analogues on Leishmania amazonensis | 10.1016/j.phytochem.2011.08.006 | 2011 |
Distribution of phlebotomine fauna (Diptera: Psychodidae) across an urban-rural gradient in an area of endemic visceral leishmaniasis in northern Brazil | 10.1590/s0074-02762011000800023 | 2011 |
Novel role for the double-stranded RNA-activated protein kinase PKR: modulation of macrophage infection by the protozoan parasite Leishmania | 10.1096/fj.09-140053 | 2010 |
Interaction of the monoxenic trypanosomatid Blastocrithidia culicis with the Aedes aegypti salivary gland. | 10.1016/j.actatropica.2009.11.010 | 2010 |
Leishmanicidal activity of Himathantus sucuuba latex against Leishmania amazonensis. | 10.1016/j.parint.2010.01.002 | 2010 |
Sand Fly-Leishmania Interactions: Long Relationships are Not Necessarily Easy | 2010 | |
Characterization in vivo and in vitro of a strain of Leishmania (Viannia) shawi from the Amazon Region | 10.1016/j.parint.2009.01.009 | 2009 |
Leishmania amazonensis promastigotes induce and are killed by neutrophil extracellular traps | 10.1073/pnas.0900226106 | 2009 |
Leishmanicidal effect of LLD-3 (1), a nor-triterpene isolated from Lophanthera lactescens | 10.1016/j.phytochem.2009.03.009 | 2009 |
Cooperation between Apoptotic and Viable Metacyclics Enhances the Pathogenesis of Leishmaniasis | 10.1371/journal.pone.0005733 | 2009 |
NF-kappaB-mediated repression of iNOS expression in Leishmania amazonensis macrophage infection. | 10.1016/j.imlet.2009.08.009 | 2009 |
Characterization of neutrophil extracellular traps in cats naturally infected with feline leukemia virus | 10.1099/vir.0.014613-0 | 2009 |
Salivary Gland Homogenates of Lutzomyia longipalpis and Its Vasodilatory Peptide Maxadilan Cause Plasma Leakage via PAC1 Receptor Activation | 10.1159/000197866 | 2009 |
HIV-1 infection and HIV-1 Tat protein permit the survival and replication of a non-pathogenic trypanosomatid in macrophages through TGF-?1 production | 10.1016/j.micinf.2008.02.014 | 2008 |
Protection against cutaneous leishmaniasis by intranasal vaccination with lipophosphoglycan | 10.1016/j.vaccine.2006.05.093 | 2007 |
Leishmanicidal activity of a supercritical fluid fraction obtained from Tabernaemontana catharinensis | 10.1016/j.parint.2007.01.004 | 2007 |
Development of a Ligand Blot Assay Using Biotinylated Live Cells | 10.1177/1087057107307146 | 2007 |
The FML-vaccine (Leishmune®) against canine visceral leishmaniasis: A transmission blocking vaccine | 10.1016/j.vaccine.2005.11.061 | 2006 |
Colonization of Aedes aegypti midgut by the endosymbiont-bearing trypanosomatid Blastocrithidia culicis | 10.1007/s00436-006-0154-7 | 2006 |
Interplay between parasite cysteine proteases and the host kinin system modulates microvascular leakage and macrophage infection by promastigotes of the Leishmania donovani complex | 10.1016/j.micinf.2005.06.016 | 2006 |
Increased Leishmania Replication in HIV-1-Infected Macrophages Is Mediated by Tat Protein through Cyclooxygenase-2 Expression and Prostaglandin E 2 Synthesis | 10.1086/506618 | 2006 |
Flow cytometric assessment of Leishmania spp metacyclic differentiation: Validation by morphological features and specific markers | 10.1016/j.exppara.2005.01.004 | 2005 |
The 3A1-La monoclonal antibody reveals key features of Leishmania (L) amazonensis metacyclic promastigotes and inhibits procyclics attachment to the sand fly midgut | 10.1016/j.ijpara.2005.03.004 | 2005 |
Influence of the endosymbiont of Blastocrithidia culicis and Crithidia deanei on the glycoconjugate expression and on Aedes aegypti interaction | 10.1016/j.femsle.2005.09.012 | 2005 |
Leishmania amazonensis: early proteinase activities during promastigote-amastigote differentiation in vitro | 10.1016/j.exppara.2004.10.005 | 2005 |
Anti-HIV-1 Activity of the Alkaloid Congener 18-Methoxycoronaridine | 10.1055/s-2004-827227 | 2004 |
Interaction of insect trypanosomatids with mosquitoes, sand fly and the respective insect cell lines | 10.1016/S0020-7519(03)00124-3 | 2003 |
Characterization of the species- and stage-specificity of two monoclonal antibodies against Leishmania amazonensis | 10.1016/s0014-4894(03)00098-5 | 2003 |
Leptomonas wallacei Shows Distinct Morphology and Surface Carbohydrates Composition Along the Intestinal Tract of Its Host Oncopeltus fasciatus (Hemiptera: Lygaeidae) and in Axenic Culture | 10.1111/j.1550-7408.2003.tb00262.x | 2003 |
In Vitro Activities of Iboga Alkaloid Congeners Coronaridine and 18-Methoxycoronaridine against Leishmania amazonensis | 10.1128/AAC.46.7.2111-2115.2002 | 2002 |
Leishmania (Viannia) braziliensis metacyclic promastigotes purified using Bauhinia purpurea lectin are complement resistant and highly infective for macrophages in vitro and hamsters in vivo | 10.1016/S0020-7519(02)00137-6 | 2002 |
The Replication of Human Immunodeficiency Virus Type 1 in Macrophages Is Enhanced after Phagocytosis of Apoptotic Cells | 10.1086/340412 | 2002 |
Antileishmanial Activity of an Indole Alkaloid from Peschiera australis | 10.1128/AAC.45.5.1349-1354.2001 | 2001 |
Expression of Heterologous Promoters in Lutzomyia longipalpis and Phlebotomus papatasi (Diptera: Psychodidae) Cell Lines | 10.1603/0022-2585-37.6.802 | 2000 |
Lectin-binding properties of different Leishmania species | 10.1007/s004360050597 | 1999 |
Presentation of theLeishmania antigen LACK by infected macrophages is dependent upon the virulence of the phagocytosed parasites | 10.1002/(sici)1521-4141(199903)29:03<762::aid-immu762>3.0.co;2-4 | 1999 |
Intra-Species and Stage-Specific Polymorphisms in Lipophosphoglycan Structure Control Leishmania donovani −Sand Fly Interactions - | 10.1021/bi990741g | 1999 |
Evidence that the High Incidence of Treatment Failures in Indian Kala-Azar Is Due to the Emergence of Antimony-Resistant Strains of Leishmania donovani | 10.1086/314896 | 1999 |
Cell surface characterization of amastigotes of Trypanosoma cruzi obtained from different sources | 10.1007/s004360050392 | 1998 |
Leishmania adleri , a lizard parasite, expresses structurally similar glycoinositolphospholipids to mammalian Leishmania | 10.1093/glycob/7.5.687 | 1997 |
Future of biotechnology-based control of disease in marine invertebrates. | 1995 | |
Changes in lipophosphoglycan and gene expression associated with the development of Leishmania major in Phlebotomus papatasi | 10.1017/s003118200008183x | 1995 |
Evidence that the vectorial competence of phlebotomine sand flies for different species of Leishmania is controlled by structural polymorphisms in the surface lipophosphoglycan. | 1994 | |
Saliva of Lutzomyia longipalpis Sibling Species Differs in Its Composition and Capacity to Enhance Leishmaniasis | 10.1098/rstb.1994.0097 | 1994 |
The role of the lipophosphoglycan of Leishmania in vector competence | 10.1017/S0031182000075727 | 1994 |
The effect of lectins on Leishmania - macrophage interaction | 1992 | |
Fibronectin shedding by Leishmania may influence the parasite-macrophage interaction | 1992 | |
Effect of a phorbol ester on basic surface properties of trichomonads | 10.1007/bf02782651 | 1992 |
Nuclear and cytoplasmic lectin binding sites in promastigotes of Leishmania. | 10.1177/39.6.2033238 | 1991 |
The cell surface of Crithidia fasciculata and Crithidia luciliae: oligosaccharide composition and characterization of their charged groupments | 1991 | |
The comparative fine structure and surface glycoconjugate expression of three life stages of Leishmania major | 10.1016/0014-4894(91)90137-l | 1991 |
Serum fibronectin promotes the Leishmania interaction with neutrophils and macrophages | 10.1590/s0074-02761991000700026 | 1991 |
The surface free energy of Leishmania mexicana amazonensis | 1990 | |
Anionic site behavior in Leishmania and its role in the parasite macrophage interaction | 1989 | |
Trichomonas vaginalis and Tritrichomonas foetus secrete neuraminidase into the culture medium | 10.1016/0166-6851(89)90144-8 | 1989 |
Involvement of the macrophage mannose-6-phosphate receptor in the recognition of Leishmania mexicana amazonensis | 10.1007/bf00538197 | 1987 |
Cell surface carbohydrates of L.mexicana amazonensis: differences between infective and non-infective forms | 1986 | |
Isolation and purification of amastigotes of L.mexicana amazonensis by a gradient of metrizamide | 1983 | |
Failure of hamster macrophages to discriminate between infective and non-infective promastigotes of L.donovani during attachment in vitro | 1981 |
Eventos:
(0.00% eventos com DOI)