Francois Germain Noel

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Ciências Biomédicas

Departamento:

Docentes/ICB

ORCID:

https://orcid.org/0000-0001-6813-1347


Formação:
  • Université Catholique de Louvain

    | Pós-Doutorado | 1997 - 1997
  • Université Catholique de Louvain

    | Pós-Doutorado | 1989 - 1990
  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 1983 - 1986
  • Université Catholique de Louvain

    Pharmacien D'industrie | Especialização | 1982 - 1982
  • Université Catholique de Louvain

    Sciences Pharmaceutiques | Doutorado | 1978 - 1982
  • Université Catholique de Louvain

    Sciences Pharmaceutiques | Graduação | 1973 - 1978
Laboratórios:
Nuvens de Palavras:
Artigos:
Nenhum artigo cadastrado
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Prototyping and Transmediation of Screener 2023
Um Jogo Digital para Divulgar o Processo de Descoberta e Desenvolvimento de Farmacos 2022
Effect of artemisinin derivatives on the Ca2+-ATPase activity of Schistosoma mansoni. 2007
Characterization of interactions between na,k-atpase inhibitors: synergysm, antagonism or additivity ? 2007
Contractile effects of clonazepam and 3-methylclonazepam in adult Schistosoma mansoni and their relation with benzodiazepine binding sites. 2007
Evaluation of a bufadienolide isolated from bufo schneideri werner (1894) parotoid glands secretions 2007
Evaluation of a second bufadienolide isolated from bufo schneideri werner (1894) parotid glands secretions 2007
Síntese e avaliação farmacológica de novas 1,4-naftoquinonas estruturalmente relacionadas ao lapachol 2002
Taurine protects neurons in culture against B-amyloid toxicity by activation of GABAergic neurotransmission 2002
Effect of 2-methoxy-3,8,9-trihydroxycoumestan, na original synthetic molecule on Na,K-ATPase activity 2002
Effect of PCALC21, a new synthetic quinone on GABAA receptor. 2002
Subcellular distribution of (Ca2+-Mg2+)ATPase isoforms in rat vas deferens 2002
The isoform of (Ca2+-Mg2+)ATPase present in rat vas deferens is probably SERCA2b. 2002
Investigation of ryanodine and alpha-adrenergic receptors expression after denervation of rat vas deferens 2002
Pharmacological characterization of [3H]MK-801 binding in subcellular fractions of Schistosoma mansoni 2002
Subcellular distribution of inositol 1,4,5-triphosphate receptors in Schistosoma mansoni 2002
Investigation of cellular mechanisms involved in the increased vasoconstriction response of vessels from Schistosoma mansoni 2002
Na+/K+-ATPase alpha1 and alpha2 isoforms and L-type channels expression seem not to be modulated by exogenous noradrenaline or ATP in cultured rat vas deferens 2002
Comparative pharmacokinetics of oral solution and solid form of paracetamol. 2002
Requirements for generic drug products: challenges in the design of bioequivalence studies of drug products with special characteristics 2002
Level A correlation between bioavailability and dissolution data for nimesulide immediate release tablets 2002
In vitro - in vivo correlation for two evothyroxine tablets: evaluation of the new USP conditions for the dissolution test. 2001
Expression of Na+/K+-ATPase isoforms in supersensitive cultured rat vas deferens (RVD) is not affected by noradrenaline (NA). 2001
5-HT supersensitivity of portal veins from Schistosoma mansoni infected mice: no role for increased sarcoplasmic reticulum Ca2+ mobilization 2001
Effect of PCALC36, a new synthetic coumestan, on GABAa receptor 2001
Effect of PCALC36, a new synthetic coumestan, on NA+,K+-ATPase 2001
Ca2+ -uptake and agonist-induced Ca2+ -release in microsomal vesicles from nuclear fraction of rat vas deferens 2001
Subcellular distribution of thapsigargin sensitive and resistant -(Ca2+ + Mg2+ )ATPase activity in rat vas deferens 2001
Pharmacological evaluation of antimyotoxic new coumestans with different patterns of oxygenation. 2001
Role of glutamatergic and GABAergic transmission on B-amyloid neurotoxicity. 2001
Schistosoma Mansoni Infection And Portal Vein Contraction: Investigation Of Mechanisms Involved In The Increased Vasoconstriction Response. 2001
Pharmacological Evidences For A Kainate Receptor In Schistosoma Mansoni 2001
In search of new drugs: physiology of neurotransmission and control of motility in schistosoma mansoni 2001
. Synthesis and Preliminary Pharmacological Evaluation of Coumestans with Different Patterns of Oxygenation 2001
Synthesis and Preliminary Pharmacological Evaluation of New 1,4-Naphthoquinones Structurally Related to Lapachol 2001
Comparative bioavailability of two L-thyroxine formulations in patients with hypothyroidism after multiple dose administration 2000
Síntese e avaliação farmacológica de cumestanos com diferentes padrões de oxigenação nos anéis A e D 2000
Pharmacological characterization of the ouabain high-affinity isoform of Na+ / K+ ATPase in rat testis. 2000
L-thyroxine tablets: comparative bioavailability of two products and its relation with dissolution profiles 2000
Novel ligands of the benzodiazepine site of gabaa receptor channels. 2000
Subcellular distribuition of oxalate- dependent and - independent active Ca2+ transport in rat vas deferens. 2000
Ca2+ uptake and caffeine-induced Ca2+ release in microssomes of rat vas deferens and skeletal muscle in the presence of thapsigargin 2000
Vascular pharmacological characterization of a newly synthesized drug LASSBio - 294 2000
Agonist supersensitivity of portal veins from Schistossoma mansoni infected mice 2000
Comparative bioavailability of two l-thyrixine tablets after multiple dose administration and its relation with dissolution profiles., 2000
Pharmacological characterization of kainic acid and MK-801 binding sites in subcellular fractions of Schistossoma mansoni 2000
Sympathetic denervation is associated to isoform-specific down-regulation of Na+/ K+- ATPase in rat vas deferens 2000
Regulation of voltage-dependent Ca2+ channel (vdcc) in rat vas deferens (rvd) in culture medium 2000
Preliminary pharmacological evaluation of new coumestans with diferent patterns of oxygenation 2000
Protection against glutamate-induced neurotoxicity by LASSBio-294: possible involvement of cyclic nucleotides 2000
In vitro - in vivo correlation for two evothyroxine tablets: evaluation of the new USP conditions for the dissolution test 2000
Characterization of [3H]-kainic acid binding sites in subcellular fractions of Schistosoma mansoni 1999
Radioligand binding assays in the drug discovery process: (hand-made) high-performance screening versus (robotic) high-throughput screening 1999
Down-regulation of alpha2 subunit of Na,K-ATPase in the rat vas deferens following adrenergic denervation 1999
Radioligand , enzymatic and in vitro assays for screening drugs acting on the cardiovascular system 1999
Contribution to the pharmacological profile of PCALC19, a newly synthesized antiophidic drug 1999
LASSBio-294, a newly synthesized inotropic drug, has vasodilator properties 1999
5-Hydroxytryptamine-induced contraction of mice portal vein is increased by the presence of male Schistosoma mansoni 1999
Pharmacological characterization of kainic acid binding sites in subcellular fractions of Schistosoma mansoni 1999
Control of calcium homeostasis and contractility in Schistosoma mansoni 1999
Isoform- and tissue-dependency of developmental regulations of rat Na,K-ATPase isoforms 1998
Cardiac glycoside receptors (Na,K-ATPase alpha subunit isoforms) in ventricles of Wistar-Kyoto Normotensive and Stroke-prone psontaneously hypertensive rats 1998
Ryanodine-sensitive calcium release channels in Schistosoma mansoni and their putative role in the control of calcium homeostasis 1998
Increased reactivity to 5-hydroxytryptamine of portal veins from mice infected unisexually with male Schistosoma mansoni 1998
Portal Veins Of Mice Infected With Schistosoma Mansoni Exhibit An Increased Reactivity To 5-Hydroxytryptamine 1997
(Ca-Mg)Atpase In Schistosoma Mansoni: Evidence For Heterogeneity And Resistance To Praziquantel 1997
Evidence For Functional Ryanodine Receptors In Schistosoma Mansoni Andtheir Putative Role In The Control Of Calcium Homeostasis 1997
Increase In Portal Vein Reactivity To 5-Hydroxytryptamine In Mice Infected With Schistosoma Mansoni 1997
Efeito do Miconazol Na Atividade (Ca-Mg)Atpasica do Schistosoma Mansoni 1997
Control Of Calcium Homeostasis In The Human Flatworm Schistosoma Mansoni 1997
Characterization Of An Isoform Of Na/K-Atpase With High Affinity For 3h-Ouabain In The Rat Vas Deferens 1996
Na/K-Atpase Density Is Sexually Dimorphic In The Adult Rat Kidney And Heart 1996
Caracterizacao dos Sitios de Ligacao da Rianodina Em Fracoes Sub- Celulares de Schistosoma Mansoni 1996
Sex-Linked Difference In The Number Of Na,K-Atpase In Kidneys And Hearts From Adult Rats 1996
First Evidence For The Presence Of A Na,K-Atpase With High Affinity For Ouabain In The Rat Vas Deferens 1995
There Is No Evidence For A Sexual Dimorphism Of The Na,K-Atpase In Different Organs Of The Adult Rat 1995
Separation Of Thapsigargin-Sensitive And -Resistant (Ca+Mg)Atpase Fromschistosoma Mansoni By Isopicnic Centrifugation 1995
Bn 50730 - An Hetrazepine Derivative Acts As An Irreversible Antagonist Of Paf Receptor 1994
Acao do Praziquantel Na Bomba de Ca do Schistosoma Mansoni 1994
Yangambin, A New Naturally-Occuring Platelet-Activating Factor Antagonist : Biochemical And Pharmacological Studies 1994
Subcellular Localization Of (Ca-Mg)Atpases From Schistosoma Mansoni 1994
Competition Of Yangambin, A Novel Selective Paf Antagonist, With 3h-Paf For Binding Sites In Rabbit Platelet 1993
Contribuicao Para A Localizacao Subcelular das (Ca-Mg)Atpases No Schistosoma Mansoni:Efeitos do Tamoxifen, Ph e Tapsigargina 1993
Cyclopiazonic acid and thapsigargin inhibition of (Ca-Mg)ATPase activity from Schistosoma mansoni: differences between cuticular and microsomal fractions 1992
Ontogenesis of Na,K-ATPase isoforms in rat heart and brain 1992
Identification of two classes of ouabain specific binding sites in homogenate from Schistosoma mansoni 1992
Praziquantel effects on the sucker-mediated attachment of Schistosoma mansoni in vitro and in vivo. 1992
Characterization of the furufuran lignan yangambin as a novel PAF antagonist 1992
Characterization of (Ca2+-Mg2+)-ATPase and active transport of calcium in subcellular fractions from Schistosoma mansoni 1992
A (Ca,Mg)-Atpase da Fracao Microsomal e Responsavel Pelo Transporte Ativo de Calcium No Schistosoma Mansoni. 1991
Heterogeneity of ouabain binding sites in homogenate from Schistosoma mansoni 1991
The microsomal fraction from Schistosomamansoni possesses an active transport of calcium that is coupled to the (Ca+Mg)-ATPase activity 1991
Praziquantel inhibits the sucker-mediated attachment of Schistosoma mansoni in vitro 1991
Propriedades farmacológicas das isoformas alpha e alpha+ da (Na,K)-ATPase do rato 1990
Distribuição subsarcolemática dos sítios de ligação da ouabaína e do PN200-110 no coração de rato 1990
O Praziquantel inibe a capacidade de fixação do Schistosoma mansoni in vitro 1990
Ca-Mg)-ATPase e transporte ativo de cálcio em frações subcelulares de Schistosoma mansoni 1990
Repartition of 1,4-dihydropyridine receptors between t-tubules and peripheral sarcolemma in adult and neonatal rat ventricle 1990
Efeito de Antagonistas da Calmodulina Na (Ca,Mg)-Atpase de Microssomas de Schistosoma Mansoni. 1989
Estudo Comparativo das Atpases de Transporte do Schistosoma Mansoni e do Hospedeiro: Modelo Para Descoberta de Drogas Esquistossomicidas Seletivas ? 1989
Atividade Atpasica Estimulada Pelo Ca, Dependente de Mg Em Fracoes Subcellulares do S. Mansoni. 1989
Subcellular distribution of 1,4-dihydropyridine binding sites in rat heart 1989
Characterization of a Ca2+-stimulated, Mg2+-dependent ATPase in subcellular fractions from Schistosoma mansoni 1989
Efeitos de praziquantel e oxamniquine sobre as ventosas de Schistosoma mansoni adulto. 1989
Atividade Atpasica Estimulada Pelo Ca Independente de Mg Em Preparacao de Tegumento. 1988
Diferenciacao Entre As (Na,K)-Atpases do Schistosoma Mansoni e da Ovelha Quanto Ao Efeito Inibidor do Vanadato. 1987
Use Of A Statistical Approach For The Study Of The Interaction Of Ouabain And K With (Na,K)-Atpase From Guinea-Pig And Rat Hearts. 1986
Effects Of Hycanthone, Oxamniquine And Praziquantel On (Na,K)-Atpase From Schistosoma Mansoni 1985
Aspectos Bioquimicos e Farmacologicos da (Na,K)-Atpase do Schistosoma Mansoni 1985
Some Aspects Of (Na,K)-Atpase From Schistosoma Mansoni. 1984
Na++ K+)-ATPase preparations from Schistosoma mansoni. 1984
Calcium Regulatory Mechanism Involved In The Inotropic Effect Of Digitalis. 1983
K-Dependency Of Ouabain Binding To High And Low Affinity Sites In Rat Heart Microsomes 1983
Dihydroouabain Antagonism Of Ouabain Action In Rat Heart. 1983
Inotropic Effect And Binding Sites Of Ouabain To Rat Heart. 1981
Sodium Activation Of Heart (Na,K)-Atpase From Normotensive And Hypertensive Rats. 1979
The Inhibition Of Human Heart (Na,K)-Atpase By Semisynthetic Digitalis Glycosides. 1977
Potentialisation Par Un Facteur Tissulaire de L'Inhibition de La (Na,K)-Atpase Par Le Calcium. 1977
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