Luis Mauricio Trambaioli da Rocha e Lima
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Faculdade de Farmácia
Departamento:
Departamento de Fármacos e Medicamentos
Formação:
-
Universidade de Guarulhos
Nutrição | Graduação | 2018 - 2021
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Instituto de Física de São Carlos
| Pós-Doutorado | 2005 - 2006
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Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 1997 - 2001
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Universidade Federal do Rio de Janeiro
Química Biológica | Mestrado | 1996 - 1997
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Universidade Federal do Rio de Janeiro
Farmacia | Graduação | 1991 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:
(93.40% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Oral delivery of the amylin receptor agonist pramlintide | 10.1002/pep2.24346 | 2024 |
| Spatially resolved distribution of pancreatic hormones proteoforms by MALDI-imaging mass spectrometry | 10.1016/j.ab.2024.115570 | 2024 |
| Mutations in asparaginase II from E. coli and implications for inactivation and PEGylation | 10.1016/j.bpc.2023.107041 | 2023 |
| Brazilian Medicinal Plants with Antiamyloidogenic Activity | 10.1007/s43450-023-00424-4 | 2023 |
| Zinc deficiency disrupts pain signaling promoting nociceptive but not inflammatory pain in mice | 10.1590/0001-3765202320220914 | 2023 |
| Dietary phytate induces subclinical mechanical allodynia in mice | 10.1590/1414-431x2023e12955 | 2023 |
| Modified Asparaginase For Treatment Of CancerHistorical appraisal and future perspectives | 10.2174/2452271606666230104143806 | 2023 |
| Linking B-factor and temperature-induced conformational transition | 10.1016/j.bpc.2023.107027 | 2023 |
| Nutrient-sensing amyloid metastasis | 10.1002/biof.1825 | 2022 |
| The reproducible normality of the crystallographic B-factor | 10.1016/j.ab.2022.114594 | 2022 |
| Formation of subvisible particles in commercial insulin formulations | 10.1016/j.colsurfb.2022.112566 | 2022 |
| Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2 | 10.1016/j.bpc.2021.106554 | 2021 |
| Polymeric microparticle systems for modified release of glucagon-like-peptide-1 receptor agonists | 10.1080/02652048.2021.1889059 | 2021 |
| Amyloidogenicity of peptides targeting diabetes and obesity | 10.1016/j.colsurfb.2021.112157 | 2021 |
| Unambiguous characterization of |
10.1002/pep2.24252 | 2021 |
| Dietary zinc restriction promotes degeneration of the endocrine pancreas in mice | 10.1016/j.bbadis.2020.165675 | 2020 |
| Physicochemical and structural properties of lunasin revealed by spectroscopic, chromatographic and molecular dynamics approaches | 10.1016/j.bbapap.2020.140440 | 2020 |
| Amyloidogenesis of feline amylin and plasma levels in cats with diabetes mellitus or pancreatitis | 10.1016/j.domaniend.2020.106532 | 2020 |
| Vancomycin-loaded nanoparticles against vancomycin intermediate and methicillin resistant Staphylococcus aureus strains | 10.1088/1361-6528/ab97d7 | 2020 |
| BZ043, a novel long-acting amylin analog, reduces gastric emptying, food intake, glycemia and insulin requirement in streptozotocin-induced diabetic rats | 10.1016/j.peptides.2019.04.004 | 2019 |
| Insulin resistance underlying type 2 diabetes | 10.1016/S2213-8587(19)30147-0 | 2019 |
| Physico-chemical stability of co-formulation of PEGylated human amylin with insulin | 10.1080/10837450.2019.1621896 | 2019 |
| Sustained release and pharmacologic evaluation of human glucagon-like peptide-1 and liraglutide from polymeric microparticles | 10.1080/02652048.2019.1677795 | 2019 |
| Heterotropic Modulation of Amylin Fibrillation by Small Molecules: Implications for Formulative Designs | 10.1007/s10930-019-09877-w | 2019 |
| The toxic nature of murine amylin and the immune responsivity of pancreatic islet to conformational antibody in mice | 10.1007/s11010-018-3288-x | 2018 |
| Physico-chemical properties of co-formulated fast-acting insulin with pramlintide | 10.1016/j.ijpharm.2018.06.039 | 2018 |
| BZ043, a Novel Amylin Analog, in a Fixed Combination with Insulin Glargine-Nonclinical Results | 10.2337/db18-76-OR | 2018 |
| Biologically produced silver chloride nanoparticles from B. megaterium modulate interleukin secretion by human adipose stem cell spheroids | 10.1007/s10616-018-0257-x | 2018 |
| Monitoring asparaginase activity | 10.1016/s1470-2045(18)30656-9 | 2018 |
| Oligomeric transition and dynamics of RNA binding by the HuR RRM1 domain in solution | 10.1007/s10858-018-0217-y | 2018 |
| Prediabetes definitions and clinical outcomes | 10.1016/S2213-8587(17)30011-6 | 2017 |
| Re: Efficacy and effectiveness of screen and treat policies in prevention of type 2 diabetes: systematic review and meta-analysis of screening tests and interventions | 2017 | |
| Subclinical Diabetes | 10.1590/0001-3765201720160394 | 2017 |
| End Functionalization by Ring Opening Polymerization: Influence of Reaction Conditions on the Synthesis of End Functionalized Poly(lactic Acid) | 10.21577/0103-5053.20170118 | 2017 |
| Publish and perish in the hands of predatory journals | 10.1590/0001-37652017892 | 2017 |
| Comprehensive structural analysis of designed incomplete polypeptide chains of the replicase nonstructural protein 1 from the severe acute respiratory syndrome coronavirus | 10.1371/journal.pone.0182132 | 2017 |
| Macromolecular confinement of therapeutic protein in polymeric particles for controlled release: insulin as a case study | 10.1590/s2175-97902017000216039 | 2017 |
| Polymorphic distribution of proteins in solution by mass spectrometry: The analysis of insulin analogues | 10.1016/j.biologicals.2016.09.011 | 2017 |
| Pharmacopeia and ANVISA: A Necessary Symbiosis | 10.30968/rbfhss.2017.084.001 | 2017 |
| Yeast-derived biosynthesis of silver/silver chloride nanoparticles and their antiproliferative activity against bacteria | 10.1039/c5ra22727e | 2016 |
| Refolding, purification, and preliminary structural characterization of the DNA-binding domain of the quorum sensing receptor RhlR from Pseudomonas aeruginosa | 10.1016/j.pep.2016.01.006 | 2016 |
| Regulation of the assembly and amyloid aggregation of murine amylin by zinc | 10.1016/j.bpc.2016.09.008 | 2016 |
| Green production of microalgae-based silver chloride nanoparticles with antimicrobial activity against pathogenic bacteria | 10.1016/j.enzmictec.2016.10.018 | 2016 |
| Amyloidogenesis of the amylin analogue pramlintide | 10.1016/j.bpc.2016.09.007 | 2016 |
| Assignment of polymorphic species of insulin analogues in ion mobility mass spectroscopy | 10.1016/j.dib.2016.12.020 | 2016 |
| Allosteric regulation of the Plasmodium falciparum cysteine protease falcipain-2 by heme | 10.1016/j.abb.2015.03.007 | 2015 |
| Molecular confinement of human amylin in lipidic nanoparticles | 2015 | |
| Monoconjugation of Human Amylin with Methylpolyethyleneglycol | 10.1371/journal.pone.0138803 | 2015 |
| Effect of tamoxifen in RAFT miniemulsion polymerization during the synthesis of polymeric nanoparticles | 10.4322/polimeros.2014.050 | 2014 |
| Synthesis of Nanoparticles Loaded with Tamoxifen by Miniemulsion RAFT Polymerization | 10.1002/masy.201400025 | 2014 |
| Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycle | 10.1016/j.bbapap.2014.12.008 | 2014 |
| Amylin induces hypoglycemia in mice | 2013 | |
| A T3R3 hexamer of the human insulin variant B28Asp | 10.1016/j.bpc.2013.01.003 | 2013 |
| Assembly Stoichiometry of bacterial Selenocysteine Synthase and SelC (tRNAsec) | 10.1016/j.febslet.2013.02.014 | 2013 |
| Inhibition of Human Transthyretin Aggregation by Non-Steroidal Anti-Inflammatory Compounds: A Structural and Thermodynamic Analysis | 10.3390/ijms14035284 | 2013 |
| Falcipain-2 inhibition by suramin and suramin analogues | 10.1016/j.bmc.2013.04.047 | 2013 |
| Structural meta-analysis of regular human insulin in pharmaceutical formulations | 10.1016/j.ejpb.2013.05.005 | 2013 |
| Preparation and Characterization of PEGylated Amylin | 10.1208/s12249-013-9987-4 | 2013 |
| Amylin Conjugation with Methoxyl Polyethyleneglycol | 10.2174/09298665113209990067 | 2013 |
| Stepwise oligomerization of murine amylin and assembly of amyloid fibrils | 10.1016/j.bpc.2013.07.013 | 2013 |
| Conformational dissection of Thermomyces lanuginosus lipase in solution | 10.1016/j.bpc.2013.12.001 | 2013 |
| A fluorescence-based assay for octreotide in the kinetic release from depot formulations | 2012 | |
| Polymeric particles for the controlled release of human amylin | 10.1016/j.colsurfb.2012.01.021 | 2012 |
| Allosteric activation of human ¿-thrombin through exosite 2 by suramin analogs | 10.1016/j.abb.2012.02.001 | 2012 |
| Evaluation of the Antioxidant and Phototoxic Potentials of Bauhinia microstachya var. massambabensis Vaz Leaf Extracts | 2012 | |
| Allosteric function and dysfunction of the prion protein | 10.1007/s00018-011-0847-7 | 2012 |
| Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis | 10.1016/j.jsb.2012.07.008 | 2012 |
| 2,4-Dinitrophenol reduces the reactivity of Lys553 in the lower 50-kDa region of myosin subfragment 1 | 10.1016/j.abb.2010.09.022 | 2011 |
| The binding of synthetic triiodo l-thyronine analogs to human transthyretin: Molecular basis of cooperative and non-cooperative ligand recognition | 10.1016/j.jsb.2010.10.003 | 2011 |
| Chemical stability study of vitamins thiamine, riboflavin, pyridoxine and ascorbic acid in parenteral nutrition for neonatal use | 10.1186/1475-2891-10-47 | 2011 |
| Structure and Behavior of Human ¿-Thrombin upon Ligand Recognition: Thermodynamic and Molecular Dynamics Studies | 10.1371/journal.pone.0024735 | 2011 |
| On the Denaturation Mechanisms of the Ligand Binding Domain of Thyroid Hormone Receptors | 10.1021/jp911554p | 2010 |
| Recognition by thyroid hormone receptor of canonical DNA response elements | 10.1021/bi901282s | 2010 |
| Identification of a novel ligand binding motif in the transthyretin channel | 10.1016/j.bmc.2009.11.025 | 2010 |
| Magnetic field sensor based on a maghemite/polyaniline hybrid material | 10.1007/s10853-010-4321-y | 2010 |
| Conformational differences between the wild type and V30M mutant transthyretin modulate its binding to genistein: Implications to tetramer stability and ligand-binding | 10.1016/j.jsb.2010.03.002 | 2010 |
| Novel Zn2+-binding sites in human transthyretin: implications for amyloidogenesis and retinol binding protein recognition | 10.1074/jbc.M110.157206 | 2010 |
| Response to Radulescu and Brenig: Infectious nucleic acids in prion disease: halfway there | 10.1016/j.tibs.2008.10.001 | 2009 |
| Enhanced prion protein stability coupled to DNA recognition and milieu acidification | 10.1016/j.bpc.2008.12.011 | 2009 |
| Structural and thermodynamic analysis of thrombin:suramin interaction in solution and crystal phases | 10.1016/j.bbapap.2009.03.011 | 2009 |
| Cognate DNA Stabilizes the Tumor Suppressor p53 and Prevents Misfolding and Aggregation | 10.1021/bi9003028 | 2009 |
| Reciprocal remodeling upon binding of the prion protein to its signaling partner hop/STI1 | 10.1096/fj.09-138974 | 2009 |
| Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins | 10.1021/ar900179t | 2009 |
| Functionality of phosphorylated vicilin exposed to chemical and physical agents. | 10.1016/j.foodchem.2007.09.077 | 2008 |
| The intriguing nucleic-acid binding properties of the prion protein. | 10.1016/j.tibs.2007.11.003 | 2008 |
| Characterization of the papillomavirus α1E2 peptide unfolded to folded transition upon DNA binding | 10.1016/j.febslet.2008.09.041 | 2008 |
| Low-resolution structure and fluorescence anisotropy analysis of protein tyrosine phosphatase η catalytuc domain | 10.1529/biophysj.106.094961 | 2007 |
| Specificity in DNA recognition by a peptide from E2 protein of papillomavirus | 10.1016/j.febslet.2006.02.047 | 2006 |
| Tetramerization of the LexA repressor in solution. Implications for gene regulation of the E. coli SOS system at acidic pH. | 10.1016/j.jmb.2006.03.069 | 2006 |
| Structural insights into the interaction between prion protein and nucleic acid | 10.1021/bi060532d | 2006 |
| The amino terminal PrP domain is crucial to modulate prion misfolding and aggregation | 10.1529/biophysj.105.067603 | 2005 |
| Highlights of the 3rd International Conference on High Pressure Bioscience and Biotechnology | 10.1590/S0100-879X2005000800001 | 2005 |
| New insights into conformational and functional stability of human alpha-thrombin probed by high hydrostatic pressure | 10.1111/j.0014-2956.2004.04295.x | 2004 |
| Hydration and packing effects on prion folding and b-sheet conversion: Pressure spectroscopy and pressure calorimetry studies | 2004 | |
| Reversible aggregation plays a crucial role on the folding landscape of p53 core domain | 10.1529/biophysj.104.044685 | 2004 |
| Desenvolvimento e estabilidade de suspensões de sulfasalazina em xarope | 2004 | |
| Positive contribution of hydration on DNA binding by E2 protein from papillomavirus | 10.1074/jbc.M407696200 | 2004 |
| Role of hydration in the closed-to-open transition involved in Ca binding by troponin C | 10.1021/bi027102h | 2003 |
| Modulation of Prion Protein Oligomerization, Aggregation, and -sheet Conversion by 4,4'-Dianilino-1,1'-binaphthyl-5,5'-sulfonate (bis-ANS) | 10.1074/jbc.M312262200 | 2003 |
| Pressure induces folding intermediates that are crucial for protein-DNA recognition and virus assembly (Review) | 10.1016/S0167-4838(01)00348-X | 2002 |
| p-Nitrophenylphosphatase activity catalyzed by plasma membrane (Ca(2+) + Mg(2+)ATPase: correlation with structural changes modulated by glycerol and Ca(2+). | 10.1023/A:1010477916631 | 2001 |
| Isolation and Chemical Analysis of a Fatty Acid Fraction of Kalanchoe pinnata with a Potent Lymphocyte Suppressive Activity | 10.1055/s-2000-11131 | 2000 |
| DNA tightens the dimeric DNA-binding domain of human papillomavirus E2 protein without changes in volume | 10.1073/pnas.250352197 | 2000 |
| Distinctive cognate sequence discrimination, bound DNA conformation, and binding modes in the E2 C-terminal domains from prototype human and bovine papillomaviruses. | 10.1021/bi001694r | 2000 |
| Folding of a dimeric ?-barrel: Residual structure in the urea denatured state of the human papillomavirus E2 DNA binding domain | 10.1110/ps.9.4.799 | 2000 |
| Conformational Changes and Stabilization Induced by Ligand Binding in the DNA-binding Domain of the E2 Protein from Human Papillomavirus | 10.1074/jbc.272.31.19295 | 1997 |
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