Chaquip Daher Netto

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Campus de Macaé

Unidade:

Direção Geral/Macaé

Departamento:

Docentes do Campus UFRJ/Macaé

ORCID:

https://orcid.org/0000-0001-5627-6856


Formação:

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2007 - 2008

  • Universidade Federal do Rio de Janeiro

    Química de Produtos Naturais | Doutorado | 2003 - 2007

  • Universidade Federal do Rio de Janeiro

    Química de Produtos Naturais | Mestrado | 2001 - 2003

  • Universidade Federal do Rio de Janeiro

    Farmácia | Graduação | 1996 - 2000
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:

(91.89% artigos com DOI)

Titulo DOI Ano
Flavonoids as Inspiration for the Design and Synthesis of New Antiproliferative, Antiparasitic and Antiviral Compounds: An Account 10.21577/0103-5053.20240056 2024
LQB-118 Suppresses Migration and Invasion of Prostate Cancer Cells by Modulating the Akt/GSK3β Pathway and MMP-9/Reck Gene Expression 10.21873/anticanres.16171 2023
Copper(I)/Triphenylphosphine Complexes Containing Naphthoquinone Ligands as Potential Anticancer Agents 10.3390/inorganics11090367 2023
Partial characterization and anticoagulant activity of sulfated galactan from the green seaweed Halimeda opuntia 10.1590/0001-3765202320211002 2023
Effects of anti¿ Leishmania compounds in the behavior of the sand fly vector Lutzomyia longipalpis 10.1002/ps.6900 2022
Novel Ru(II)-bipyridine/phenanthroline-lapachol complexes as potential anti-cancer agents 10.1016/j.jinorgbio.2022.112005 2022
Lapachol in the Design of a New Ruthenium(II)-Diphosphine Complex as a Promising Anticancer Metallodrug 10.1016/j.jinorgbio.2020.111289 2021
The pterocarpanquinone LQB¿118 compound induces apoptosis of cytarabine¿resistant acute myeloid leukemia cells 10.3892/ijo.2021.5204 2021
Cross-Coupling Reactions with 2-Amino-/Acetylamino-Substituted 3-Iodo-1,4-naphthoquinones: Convenient Synthesis of Novel Alkenyl- and Alkynylnaphthoquinones and Derivatives 10.1055/s-0037-1610781 2021
The pterocarpanquinone LQB 118 inhibits inflammation triggered by zymosan in vivo and in vitro 10.1016/j.intimp.2020.106399 2020
Medicinal Electrochemistry of Halogenated and Nitrated Pterocarpanquinones 10.21577/0103-5053.20190161 2019
LQB-118 compound inhibits migration and induces cell death in glioblastoma cells 10.3892/or.2019.7402 2019
New strategies for the synthesis of naphthoquinones employing Cu(II) complexes: Crystal structures and cytotoxicity 10.1016/j.molstruc.2017.08.066 2018
Second-generation pterocarpanquinones: synthesis and antileishmanial activity 10.1186/s40409-018-0174-7 2018
Preparative Chiral Separation and Absolute Configuration of the Synthetic Pterocarpanquinone LQB-118 10.1002/chir.22696 2017
Synthesis of Stilbene-Quinone Hybrids through Heck Reactions in PEG-400 10.1055/s-0036-1589095 2017
In vitro and in vivo antineoplastic and immunological effects of pterocarpanquinone LQB-118 10.1007/s10637-016-0359-2 2016
Preclinical studies of LQB-118: subacute toxicity and therapeutic evaluation in experimental visceral leishmaniasis. 10.1128/aac.01787-15 2016
Anti-Inflammatory Properties of Pterocarpanquinone LQB-118 in Mice 10.1016/j.bmc.2016.07.046 2016
ROS release, alkylating ability and DNA interaction of a pterocarpanquinone: a test case for electrochemistry 10.1002/celc.201600504 2016
Palladium-Catalyzed Oxyarylation, Azaarylation and 10.2174/157017941206150828112502 2015
Further evidence that naphthoquinone inhibits Toxoplasma gondii growth in vitro 10.1016/j.parint.2015.08.010 2015
Ligand-Free Palladium-Catalyzed Oxyarylation of Dihydronaphthal­enes and Chromenequinone with o-Iodophenols and 3-Iodolawsone in PEG-400: An Efficient Synthesis of 5-Carbapterocarpans and Pterocarpanquinones 10.1055/s-0034-1378745 2015
The pterocarpanquinone LQB-118 inhibits tumor cell proliferation by downregulation of c-Myc and cyclins D1 and B1 mRNA and upregulation of p21 cell cycle inhibitor expression 10.1016/j.bmc.2014.04.025 2014
LQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis 10.1093/jac/dks498 2013
Purification of a synthetic naphthoquinone pterocarpanquinone by counter-current chromatography 2012
A new type of pterocarpanquinone that affects Toxoplasma gondii tachyzoites in vitro 10.1016/j.vetpar.2011.11.008 2012
LQB-118, a pterocarpanquinone structurally related to lapachol [2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone]: a novel class of agent with high apoptotic effect in chronic myeloid leukemia cells 10.1007/s10637-010-9453-z 2011
Pterocarpanquinones, aza-pterocarpanquinone and derivatives: Synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis 10.1016/j.bmc.2011.09.025 2011
Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis 10.1093/jac/dkr158 2011
New pterocarpanquinones: Synthesis, antineoplasic activity on cultured human malignant cell lines and TNF-a modulation in human PBMC cells 10.1016/j.bmc.2009.12.073 2010
Comparison of the cytotoxic effect of lapachol, ?-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells 10.1007/s10637-009-9231-y 2010
Antitumoral, Antileishmanial and Antimalarial Activity of Pentacyclic 1,4-Naphthoquinone Derivatives 2009
(±)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: Cytotoxic effect on human leukemia cell lines 10.1016/j.ejmech.2008.01.027 2009
Insights into the mechanism of Na+/K+-ATPase inhibition by 2-methoxy-3,8,9-trihydroxy coumestan 10.1016/j.bmc.2008.09.007 2008
Structure?activity relationship of wedelolactone analogues: Structural requirements for inhibition of Na+,K+-ATPase and binding to the central benzodiazepine receptor 10.1016/j.bmc.2006.07.053 2006
The First Synthesis of (±)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan, an AntitumoralAgent and its Coumestan Derivative 2004
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
LQB 118, a Novel Antineoplastic Agent, Induces Alteration on Thymus Cell Subpopulation in vivo. 2010
Induction of apoptosis in leukemia cells by lqb 118, the novel compound with pterocarpanquinone moiety. 2009
Efeito Antitumoral de uma quinona sintética em linhagens tumorais normais e resistentes a múltiplas drogas. 2007
Synthesis Antiproliferative Effect (MCF-7 cell line), Antimalarial Activity (Plasmodium falciparum FcB1 strain) and Antileishmanial Activity (Leishmania amazonensis) of New pentacyclic 1,4-Naphthoquinones 2006
The Cytotoxic Effect of Pterocarpans and Structurally Related Pentacyclic 1,4-Nathphoquinones Against Human Leukemia Cell Lines 2006
Structure-Activity Relationship of Wedelolactone Analogues: Structural Requirements for Inhibition of Na,K-ATPase and Binding to the Central Benzodiazepine Receptor 2006
Síntese de Pterocarpanos com um Novo Padrão de Substituição no Anel A 2004
Pterocarpanquinones with Antiploriferative Action in Erytroleukemia (K562 ad Lucena I Cells) in Culture 2004
Publicações:
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