Adriane Regina Todeschini

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biologia Celular e Parasitária/Biof

ORCID:

não disponível no Lattes


Formação:

  • Boston University

    | Pós-Doutorado | 2014 - Agora

  • University of Washington

    | Pós-Doutorado | 2005 - 2007

  • Universite de Limoges

    Intercâmbio Internacional | Especialização | 2004 - 2004

  • Universite de Limoges

    Intercâmbio Internacional | Especialização | 2003 - 2003

  • University of California System

    Glycobiology | Especialização | 1998 - 1998

  • Universidade Federal do Rio de Janeiro

    Química de Produtos Naturais | Doutorado | 1995 - 1999

  • Universidade Federal do Rio de Janeiro

    Química de Produtos Naturais | Mestrado | 1993 - 1995

  • Universidade Federal do Rio Grande do Sul

    Farmácia | Graduação | 1986 - 1992

  • Governo do Estado do Rio Grande do Sul

    Técnico Em Química | Ensino Profissional de nível técnico | 1983 - 1985
Laboratórios:
Nuvens de Palavras:
Artigos:

(86.11% artigos com DOI)

Titulo DOI Ano
Sex-specific effect of antenatal Zika virus infection on murine fetal growth, placental nutrient transporters, and nutrient sensor signaling pathways 10.1096/fj.202301951RR 2024
Interfacing manganese-based carbonaceous nanocomposites with plasma components: insights on protein interaction, structure and opsonization 10.1080/07391102.2023.2195943 2023
Development and clinical application of hydrogel formulations containing papain and urea for wound healing 10.1590/s2175-97902023e201090 2023
From metabolism to disease: the biological roles of glutamine:fructose-6-phosphate amidotransferase (GFAT) 10.1515/pac-2023-0503 2023
Inhibition of O-GlcNAcylation Reduces Cell Viability and Autophagy and Increases Sensitivity to Chemotherapeutic Temozolomide in Glioblastoma 10.3390/cancers15194740 2023
Hyperglycemia alters N-glycans on colon cancer cells through increased production of activated monosaccharides 10.1007/s10719-022-10057-9 2022
GM2/GM3 controls the organizational status of CD82/Met microdomains: further studies in GM2/GM3 complexation 10.1007/s10719-022-10061-z 2022
BDE-209 and TCDD enhance metastatic characteristics of melanoma cells after chronic exposure 10.1016/j.envpol.2022.120140 2022
Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2) 10.1074/jbc.ra120.015189 2021
Evaluation of europium-based carbon nanocomposites as bioimaging probes: Preparation, NMR relaxivities, binding effects over plasma proteins and cytotoxic aspects 10.1016/j.colsurfa.2021.127250 2021
Trends In Nanotechnology For In Vivo Cancer Diagnosis: Products And Patents 10.2174/1381612826666200219094853 2020
Trends In Nanomedicines For Cancer Treatment 10.2174/1381612826666200318145349 2020
Hyperglycemia enhances cancer immune evasion by inducing alternative macrophage polarization through increased O-GlcNAcylation 10.1158/2326-6066 2020
Biological evaluation and molecular modeling of peptidomimetic compounds as inhibitors for O-GlcNAc transferase (OGT) 10.1016/j.ejps.2020.105510 2020
Insights on the interaction of furfural derivatives with BSA and HTF by applying multi-spectroscopic and molecular docking approaches 10.1016/j.molliq.2020.114021 2020
The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19) 10.1038/s41598-020-76781-0 2020
Duffy binding-like 1α adhesin from Plasmodium falciparum recognizes ABH histo-blood group saccharide in a type specific manner 10.1016/j.carbpol.2018.11.082 2019
Targeting the Hexosamine Biosynthetic Pathway Prevents Plasmodium Developmental Cycle and Disease Pathology in Vertebrate Host 10.3389/fmicb.2019.00305 2019
Hexosamine Biosynthetic Pathway and Glycosylation Regulate Cell Migration in Melanoma Cells 10.3389/fonc.2019.00116 2019
Emerging Role of Glycosylation in the Polarization of Tumor-Associated Macrophages 10.1016/j.phrs.2019.104285 2019
Probing the interaction of carbonaceous dots with transferrin and albumin: Impact on the protein structure and non-synergetic metal release 10.1016/j.molliq.2019.111460 2019
CD43 sialoglycoprotein modulates cardiac inflammation and murine susceptibility to Trypanosoma cruzi infection 10.1038/s41598-019-45138-7 2019
Hyperglycemia and aberrant O-GlcNAcylation: contributions to tumor progression 10.1007/s10863-017-9740-x 2018
Prevalence of IgG Autoantibodies against GD3 Ganglioside in Acute Zika Virus Infection 10.3389/fmed.2018.00025 2018
N-linked glycosylation restricts the function of short gastrulation to bind and shuttle BMPs 10.1242/dev.167338 2018
Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway 10.1038/oncsis.2017.2 2017
Cellular glycosylation senses metabolic changes and modulates cell plasticity during EMT 10.1002/dvdy.24553 2017
Epithelial mesenchymal transition induces aberrant glycosylation through hexosamine biosynthetic pathway activation 10.1074/jbc.m116.729236 2016
Expression of leukosialin (CD43) defines a major intrahepatic T cell subset associated with protective responses in visceral leishmaniasis 10.1186/s13071-015-0721-9 2015
Biosynthetic Machinery Involved in Aberrant Glycosylation: Promising Targets for Developing of Drugs Against Cancer 10.3389/fonc.2015.00138 2015
CALCIUM-INDUCED LIPID PEROXIDATION IS MEDIATED BY RHODNIUS HEME-BINDING PROTEIN (RHBP) AND PREVENTED BY VITELLIN 10.1002/arch.21248 2015
Sperm and Egg Jelly Coat from Sea Urchin Lytechinus variegatus Collected in Rio de Janeiro Contain Distinct Sialic Acid-Rich Polysaccharides 10.1590/s1516-8913201500052 2015
Evidences for the involvement of cell surface glycans in stem cell pluripotency and differentiation 10.1093/glycob/cwu012 2014
Evidences of ternary complex formation in Trypanosoma cruzi trans-sialidase catalysis 10.1074/jbc.m112.399303 2014
Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes 10.1016/j.micinf.2013.02.003 2013
Increase of O-Glycosylated Oncofetal Fibronectin in High Glucose-Induced Epithelial-Mesenchymal Transition of Cultured Human Epithelial Cells 10.1371/journal.pone.0060471 2013
Inhibitory Effects of Trypanosoma cruzi Sialoglycoproteins on CD4+ T Cells Are Associated with Increased Susceptibility to Infection 10.1371/journal.pone.0077568 2013
Role of the 9-O-acetyl GD3 in subventricular zone neuroblast migration 10.1016/j.mcn.2011.08.010 2012
Sialic acid: a sweet swing between mammalian host and Trypanosoma cruzi 10.3389/fimmu.2012.00356 2012
Further structural characterization of the Echinococcus granulosus laminated layer carbohydrates: the blood antigen P1-motif gives rise to branches at different points of the O-glycan chains 10.1093/glycob/cws220 2012
Structural elucidation of the repeat unit in highly branched acidic exopolysaccharides produced by nitrogen fixing Burkholderia 10.1093/glycob/cwp181 2010
Trypanosoma cruzi Subverts Host Cell Sialylation and May Compromise Antigen-specific CD8+ T Cell Responses 10.1074/jbc.M109.096305 2010
A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence 10.1093/glycob/cwq065 2010
The trans-Sialidase from Trypanosoma cruzi a Putative Target for Trypanocidal Agents 2010
Overlooked post-translational modifications of proteins in Plasmodium falciparum: N- and O-glycosylation - A Review 10.1590/S0074-02762010000800001 2010
α-N-acetylglucosamine-linked O-glycans of sialoglycoproteins (Tc-mucins) from Trypanosoma cruzi Colombiana strain 10.1590/S0074-02762009000900035 2009
The Major Surface Carbohydrates of the Echinococcus granulosus Cyst: Mucin-Type O -Glycans Decorated by Novel Galactose-Based Structures 10.1021/bi901112q 2009
Endothelial cell signaling induced by trans-sialidase from Trypanosoma cruzi. 10.1111/j.1462-5822.2007.01017.x 2008
Ganglioside GM2/GM3 complex affixed on silica nanospheres strongly inhibits cell motility through CD82/cMet-mediated pathway 10.1073/pnas.0709619104 2008
Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains. 10.1016/j.bbagen.2007.10.008 2008
Characterization of two heparan sulphate-binding sites in the mycobacterial adhesin Hlp 10.1186/1471-2180-8-75 2008
Chemical Structure of Major Glycoconjugates from Parasites 2008
Endophytic colonization of rice (Oryza sativa L.) by the diazotrophic bacterium Burkholderia kururiensis and its ability to enhance plant growth 10.1590/S0001-37652008000300009 2008
Inclusão do Filtro Solar p-Metoxicinamato de Octila em β-Ciclodextrina e Avaliação da Purificação dos Complexos de Inclusão por RMN 1H 2008
Antiplatelet activity of Geranylgeraniol isolated from Pterodon pubescens fruits oil is mediated by inhibition of Cyclooxygenase-1 10.1055/s-2007-967177 2007
Ganglioside GM2/ tetraspanin CD82 complex inhibits Met activation, and its cross-talk with integrins: Basis for control of cell motility through glycosynapse 10.1074/jbc.m611407200 2007
Nitrogen-fixing bacterium Burkholderia brasiliensis produces a novel Yersiniose A-containing O-polysaccharide 10.1093/glycob/cwi009 2005
Antinociceptive properties of ethanolic extract and fractions of Pterodon pubescens Benth seeds 10.1016/j.jep.2005.01.014 2005
Parasite-specific carbohydrate structures 10.1016/j.sbi.2005.08.011 2005
Glycoinositolphospholipids from Trypanosoma cruzi: structure, biosynthesis and Immunology 10.1016/S0065-308X(03)56001-8 2004
Acute and Topic Anti-edematogenc Fractions Isolated from the Seeds of Pterodon pubescens 10.1211/0022357022485 2004
Enzymatically inactive trans-sialidase from Trypanosoma cruzi binds sialyl and â-galactopyranosyl residues in a sequential-ordered mechanism 10.1074/jbc.M310663200 2004
Heterogeneity in the Biosynthesis of Mucin O-glycans from Trypanosoma cruzi Tulahuen Strain with the Expression of Novel Galactofuranosyl-containing -O-GlcNAc-linked Oligosaccharides 10.1021/bi048942u 2004
A novel sialylated and galactofuranose-containing O-linked glycan, Galf 1 4 [Neu5Ac 2 3Galp 1 6] GlcNAc, is expressed on the sialoglycoprotein of Trypanosoma cruzi Dm28c 10.1016/S0166-6851(02)00245-1 2003
Costimulation of host T lymphocytes by a trypanosomal trans-sialidase: involvement of CD43 signaling 2002
Trans-sialidase from Trypanosoma cruzi binds host T-lymphocytes in a lectin manner 10.1074/jbc.M203185200 2002
Structures of O-glycosidically linked oligosaccharides from glycoproteins of Trypanosoma cruzi CL-Brener strain: Evidence for the presence of O-linked sialyloligossaccharides 2001
A novel family of glycophosphosphingolipid expressed by yeast forms of Sporothrix schenckii: evidence for a unique mana1-6Ins-phosphorylceramide substructure 2001
Trans-sialidase from Trypanosoma cruzi catalyzes sialoside hydrolysis with retention of configuration 2000
Synthesis of new 2-pyridylarylhydrazones derivatives and analysis of their analgesic, antiinflammatory and antiplatelet profile 1998
Pyridylarylhydrazones Derivatives a New Class of Platelet Aggregation Inhibitors 1996
Otimização de Processos para Obtenção de Fenitoína 1992
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Hyperglycemia affects the glycophenotype and increases tumor progression and metastasis of murine colon carcinoma cell 2015
Impacto da hiperglicemia no microambiente tumoral 2015
Hiperglicemia altera o glicofenótipo extracelular e aumenta motilidade de células de câncer de cólon murino 2015
Hyperglycemia induces the biosynthesis of aberrant glycoconjugates and cell migration of murine colon carcinoma cells (MC38) 2015
Papel da via das hexosaminas na progressão tumoral 2015
Hyperglycemia affects the glycophenotype and the grwth of volon carcinoma cells in vivo 2013
Studies on glycosylinositolphosphoceramide isolated from Sporothrix schenckii-infected domestic felines 2011
trans-sialidase from Trypanosoma cruzi mediates immature thymocyte release into peripheral lymph nodes 2011
INVOLVEMENT OF CD43-MEDIATED T CELL HOMING IN PATHOGENESIS OF CHAGASIC CARDIOMIOPATHY 2009
Involvement of CD43 (Leukosialin) in pathogenesis of chagasic cardiomiopathy 2009
Trypanosoma cruzi explores CD8+ T cell sialylation to dampen Ag-specific CD8+ T cell response. 2009
Involvement of CD43-mediated T cell homing in pathogenisis of experimental of experimental chagasic cardiomiopathy: elucidation of a mechanism to exploit as a therapeutical target during Trypanosoma cruzi infection. 2009
Alteration of CD8+ cell surfacesialylation by trans-sialidase activity during Trypanosoma cruzi infection. 2008
of CD43 modulates immune response and compromise T cells homing to heart during Trypanosoma cruzi infection. 2008
Inactive trans-sialidase compromises T cell migration to heart of Trypanosoma cruzi infected mice 2008
Absence of CD43 modulates immune response and compromise T cells homing to heart during Trypanosoma cruzi infection. 2008
Ganglioside GM2/GM3 inhibits HGF-induced cMet activation and cell motility in bladder epithelial cells, through functional organization of components in glycosynapse. 2007
Proteins from Trypanosoma cruzi trans-sialidase family play distinct roles during parasite infection. 2007
Inactive trans-sialidase from Trypanosoma cruzi binds to Annexin II on endothelial cell surface 2006
Effects of trans-sialidase on the co-stimulation and traffic of T cells during Trypanosoma cruzi infection. 2006
Neutrophil activation by inactive trans-sialidase from Trypanosoma cruzi: implications for the inflammatory response during Chagas'disease. 2006
Mapping the heparin binding sites of Hlp/LBP adhesin of Mycobacterium leprae by use synthetic peptides 2006
Ganglioside GM2/GM3 inhibits HGF-induced cMet activation and cell motility in bladder epithelial cells, through functional organization of components in glycosynapse 2006
trans-sialidase from Trypanosoma cruzi as target for chemotherapeutic intervention of Chagas'disease. 2005
Inactive trans-sialidase from Trypanosoma cruzi binds to CD43 and activates human neutrophils through ERK pathway. 2005
Endothelial cell signaling by trans-sialidase from Trypanosoma cruzi 2005
Inactive Trypanosoma cruzi trans-sialidase recognizes a 36-KDa protein on endothelial cell surface. 2005
Inactive Trypanosoma cruzi trans-sialidase blocks endothelial cell apoptosis by Bcl-2 expression. 2005
trans-sialidase from Trypanosoma cruzi promotes alterations on T-cell subsets in the hearts of infected mice. 2005
Studies of inactive trans-sialidase on the first steps in immune response to Trypanosoma cruzi infection 2005
Rational design of selective inhibitors of the trans-sialidase from Trypanosoma cruzi with potential therapeutic applications in Chagas'disease 2005
Enzymatically inactive trans-sialidase from trypanosoma cruzi binds sialyl and ß-galactopyranosyl residues in a sequential-ordered mechanism. 2004
Inhibiton of Quasi-Lipoxygenase Activity by Phosphoproteins Rely on their Phosphorylated Residues 2004
Purification and analysis of surface lipoarabinomannan from Corynebacterium diphtheriae. 2004
Modulation of cell culture trypomastigote adhesion to endothelial cells by inactive members of Trypanosoma cruzi trans-sialidase family. 2004
Modulation of host-cell death by inactive member of Trypanosoma cruzi trans-sialidase family. 2004
Cell recognition by carbohydrates during Trypanosoma cruzi infection. 2004
Role of lectinic activity of inactive trans-sialidase from Trypanosoma cruzi in the parasite-host cell interaction. 2004
Unique O-glycan biosynthesis in Trypanosoma cruzi glycoproteins 2004
Lectin/carbohydrate recognition mediate Trypanosoma cruzi infection of endothelial cells. 2004
Structure of the O-polysaccharide isolated from diazotrophic endophytic bacterium, Burkholderia brasiliensis, containing an unusual branched sugar, yersiniose A. 2004
of the binding site of Mycobacterial Hlp/LBP adhesin to glycosaminoglycans 2004
Antioxidant Effect of Hexanic and Dicloromethane Extracts of Pterodon pubescens Seeds Oil (OEPp). 2003
Trypanosoma cruzi trans-sialidase activates NF-kB and induces vascular adhesion molecule expression. 2003
Structure of the O-specific polysaccharide of the Burkholderia brasiliensis. 2003
NMR evidences that trans-sialidase from Trypanosoma cruzi binds to sialic acid containing molecules 2002
PLATELET AGGREGATION INHIBITION OF HEXANIC EXTRACTS OF Pterodon pubescens SEEDS OIL (EOPp). 2002
Structural Characterization of Glycosilinositolphosphorylceramides from Mycelium Forms of Differents Strain of Sporothrix schenckii 2002
Chemical Investigation on the Novel Carbohydrate of the Lipopolysaccharide from Burkholderia brasiliensis. 2002
An inactive member of Trypanosoma cruzi trans-sialidase family behaves as lectin. Insights into the trans-sialylation catalytic mechanism 2002
Brasiliose, a novel 4-c-branched sugar of lipopolysaccarides from the diazotrophic endophytic bacterium Burkholderia brasiliensis. 2002
Potencial antiagregante plaquetário do extrato oleoso de Pterodon pubescens (EOPp) e suas frações 2002
Propriedade antiagregante plaquetária do extrato etanólico de espécies de Baccharis (Carqueja). 2002
Does inactive members of Trypanosoma cruzi trans-sialidase family interact with its ligands by a sequential ordered or random bi bi mechanism? 2002
Mannosylinositolphosphorylceramides from Sporothrix schenkii yest forms 2001
A novel family of glycophosphosphingolipid expressed by yeast forms of Sporothrix schenckii: evidence for a unique Mana1-6Ins-phosphorylceramide substructure 2000
Trans-sialidase from Trypanosoma cruzi fully activates host t cells and dendritic cells. 2000
Chemical characterization of glycoinositol-phospholipids (GIPLS) isolated from new world leishmania specie 2000
Evidence for a sialosyl cation transition-state in the sialidase action of trans-sialidase from Trypanosoma cruzi 1999
Trans-sialidase from Trypanosoma-cruzi immunostimulates T-lymphocytes; involvement of the major lymphocyte mucin CD43. 1999
Trans-sialidase from Trypanosoma cruzi immunostimulates host T-lymphocytes 1999
Immunostimulation of host T-lymphocyte function by trans-sialidase from Trypanosoma cruzi 1998
NMR evidence of sialoside hydrolysis by Trans-sialidase from Trypanosoma cruzi with retention of configuration 1998
Trans-sialidase from Trypanosoma cruzi catalyzes sialoside hydrolisys with retention of configuration 1998
Trans-sialidase from Trypanosoma cruzi synthesizes 2-deoxy-2,3-didehydro-N-acetylneuraminic acid during the hydrolysis reaction: implications for the catalytic mechanism 1998
Novel structures of the O-GlcNAc and O-GalNAc-linked oligosaccharide chains from mucin-like molecules of protozoan parasite Trypanosoma cruzi 1997
Trans-sialidase from Trypanosoma cruzi induces polyclonal activation in normal murine CD4 T lynphocytes 1997
Novel O-linked oligosaccharides on sialoglycoprotein of Trypanosoma cruzi Tulahuen strain 1997
O-Glycosidically Linked N-Acetylglucosamine-Bound Sialylologosaccharides from Glycoproteins Trypanosoma cruzi CL-Brener strain 1996
Derivados Hidrazono-N-Heterocíclicos como Inibidores da Agregação Plaquetária 1995
Modelagem Molecular de Derivados Idrazônicos pelo método AM1 1995
N-Heterocyclic-Hydrazone Derivatives, a New Class of Anti-Platelet Agents 1995
Atividade Antiagregante de Derivados 2-Hidrazonopiridinas 1994
Atividade Antinociceptiva de 2-Piridilidrazonas 1994
Evaluation of Heterocyclic Hydrazones, Acylhidrazones and Antithrombotic Compounds. 1994
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