Wagner Seixas da Silva
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Bioquímica Médica
Departamento:
Programa de Biologia Celular e Biofisica
Formação:
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Brigham and Women's Hospital/Harvard Institute of Medicine
| Pós-Doutorado | 2004 - 2007
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Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 2000 - 2004
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Universidade Federal do Rio de Janeiro
Biologia-Genética | Graduação | 1997 - 2000
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Escola Técnica Federal de Química do Rio de Janeiro
| Ensino Médio (2o grau) | 1992 - 1996
Laboratórios:
Nuvens de Palavras:
Artigos:
(100.00% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Disruption of neuromedin B receptor improves mitochondrial oxidative phosphorylation capacity in gastrocnemius muscle of female mice | 10.1152/ajpendo.00073.2021 | 2022 |
| Sepsis Disrupts Mitochondrial Function and Diaphragm Morphology | 10.3389/fphys.2021.704044 | 2021 |
| Sepsis Impairs Thyroid Hormone Signaling and Mitochondrial Function in the Mouse Diaphragm | 10.1089/thy.2019.0124 | 2020 |
| Impact of experimental obesity on diaphragm structure, function, and bioenergetics | 10.1152/japplphysiol.00262.2020 | 2020 |
| Reduced mitochondrial respiration and increased calcium deposits in the EDL muscle, but not in soleus, from 12-week-old dystrophic mdx mice | 10.1038/s41598-019-38609-4 | 2019 |
| Sexual dimorphism of liver endoplasmic reticulum stress susceptibility in prepubertal rats and the effect of sex steroid supplementation | 10.1113/ep087518 | 2019 |
| Ciência para todos? | 10.21713/rbpg.v15i34.1606 | 2019 |
| Metformin ameliorates body mass gain and early metabolic changes in ovariectomized rats | 10.1530/ec-19-0470 | 2019 |
| Amyloid-β Oligomers Transiently Inhibit AMP-activated kinase and Cause Metabolic Defects in Hippocampal Neurons | 10.1074/jbc.M116.753525 | 2017 |
| 4-Phenyl butyric acid increases particulate hexokinase activity and protects against ROS injury in L6 myotubes | 10.1016/j.lfs.2017.05.004 | 2017 |
| Thyroid states regulate subcellular glucose phosphorylation activity in male mice | 10.1530/ec-17-0059 | 2017 |
| Evaluation of the mitochondrial system in the gonad-digestive gland complex of Biomphalaria glabrata (Mollusca, Gastropoda) after infection by Echinostoma paraensei (Trematoda, Echinostomatidae) | 10.1016/j.jip.2016.04.003 | 2016 |
| Effects of linalool and eugenol on the survival of Leishmania (L.) infantum chagasi within macrophages | 10.1016/j.actatropica.2016.08.026 | 2016 |
| Os ensinamentos herdados de um grande mestre | 10.16923/reb.v13i1.547 | 2015 |
| The unfolded protein response has a protective role in yeast models of classic galactosemia | 10.1242/dmm.012641 | 2014 |
| Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle | 10.1242/bio.20122295 | 2013 |
| Functional characterization of an uncoupling protein in goldfish white skeletal muscle | 10.1007/s10863-013-9512-1 | 2013 |
| Cardiac Expression of Human Type 2 Iodothyronine Deiodinase Increases Glucose Metabolism and Protects Against Doxorubicin-Induced Cardiac Dysfunction in Male Mice | 10.1210/en.2012-2261 | 2013 |
| The Chemical Chaperones Tauroursodeoxycholic and 4-Phenylbutyric Acid Accelerate Thyroid Hormone Activation and Energy Expenditure | 10.1016/j.febslet.2010.12.044 | 2011 |
| Characterization of the non-cytosolic hexokinase activity in the white skeletal muscle from goldfish (Carassius auratus L.) and effect of cold acclimation | 10.1042/BSR20090128 | 2010 |
| Amyloid-? Triggers the Release of Neuronal Hexokinase 1 from Mitochondria | 10.1371/journal.pone.0015230 | 2010 |
| Teaching energy metabolism using scientific articles | 10.1002/bmb.20386 | 2010 |
| Measuring the Influence of Emotional Components in a Science Education Program Through a Psychometric Approach | 10.16923/reb.v8i2.220 | 2010 |
| Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate1 | 10.1042/BJ20080805 | 2009 |
| Identification of Emotional Components to Improve the Motivation for Science Among School Teachers | 10.16923/reb.v7i2.195 | 2009 |
| Analysis of the Experience of a Virtual Learning Environment Integration Into a Biochemistry Course Offered to Undergraduate Students | 10.16923/reb.v7i2.188 | 2009 |
| Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats | 10.1172/JCI32824 | 2008 |
| The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation | 10.2337/db06-1488 | 2007 |
| Ubiquitination-Induced Conformational Change within the Deiodinase Dimer Is a Switch Regulating Enzyme Activity | 10.1128/MCB.00283-07 | 2007 |
| Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation. | 10.1074/jbc.M611214200 | 2007 |
| Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary TSH feedback mechanism. | 10.1210/en.2005-1300 | 2006 |
| Characterization of the nuclear Factor-k B responsiveness of the human dio2 gene. | 10.1210/en.2005-1608 | 2006 |
| Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinases-dependent ADP re-cycling activity. | 10.1074/jbc.M604123200 | 2006 |
| Adaptive Activation of Thyroid Hormone and Energy Expenditure | 10.1007/s10540-005-2885-6 | 2005 |
| A new model of proton pumping in animal cells: the role of pyrophosphate. | 10.1016/j.ibmb.2003.07.002 | 2004 |
| Heat of PPi hydrolysis varies depending on the enzyme used. Yeast PPase and corn vacuolar PPase. | 10.1074/jbc.M408866200 | 2004 |
| Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense: Steady State ADP Formation as a Regulatory Mechanism of Membrane Potential and Reactive Oxygen Species Generation in Mitochondria | 10.1074/jbc.m403835200 | 2004 |
| Maize tonoplast PPi-dependent H+/Ca2+ exchange: two Ks for Ca2+ and inhibition by thapsigargin. | 10.1016/S0006-291X(03)01226-9 | 2003 |
| Proton Transport in Maize Tonoplasts Supported by Fructose-1,6-Bisphosphate Cleavage. Pyrophosphate-Dependent Phosphofructokinase as a Pyrophosphate-Regenerating System | 10.1104/pp.103.026633 | 2003 |
| Hyperthyroidism increases the uncoupled ATPase activity and heat production by the sarcoplasmic reticulum Ca2+-ATPase. | 10.1042/BJ20031015 | 2003 |
| The Thermogenic Function of the Sarcoplasmic Reticulum Ca 2+ -ATPase of Normal and Hyperthyroid Rabbit | 10.1111/j.1749-6632.2003.tb07232.x | 2003 |
| Subcellular distribution and kinetic properties of cytosolic and non-cytosolic hexokinases in maize seedling roots: Implications for hexose phosphorylation | 10.1093/jexbot/52.359.1191 | 2001 |
| Hexokinase activity alters sugar-nucleotide formation in maize root homogenates | 10.1016/S0031-9422(99)00456-2 | 2000 |
| Sugar phosphorylation modulates ADP inhibition of maize mitochondrial hexokinase | 10.1034/j.1399-3054.1999.105104.x | 1999 |
Eventos:
(1.79% eventos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| O Surdo e a Ciência: aumentando a acessibilidade do jovem surdo ao conhecimento científico através do desenvolvimento de sinais técnicos/científicos em Língua Brasileira de Sinais | 2017 | |
| Efeitos dos Hormônios Tireoidianos na Atividade e Distribuição Subcelular da Hexocinase em Tecidos de Roedores | 2011 | |
| Effect of thyroid hormones on the hexokinase activity and subcellular distribution in rodents tissues | 2011 | |
| Efeito dos Hormônios Tireoidianos na Atividade e Distribuição Subcelular da Hexocinase em Tecidos de Roedores | 2010 | |
| Efeito dos Hormônios Tireoidianos na Atividade e Distribuição Subcelular da Hexocinase em Tecidos de Roedores | 2010 | |
| Efeito dos Diferentes Estados Tireoidianos nas Atividades da Hexocinase e Glicose-6-Fosfato Disidrogenase de Camundongos | 2009 | |
| Efeito dos Diferentes Estados Tireoidianos nas Atividades da Hexocinase e Glicose-6-Fosfato Disidrogenase de Camundongos | 2009 | |
| Effect of Different Thyroid States on the Subcellular Distribution of Hexokinase and Glucose 6-Phosphate Dehydrogenase Activities in Mice Tissues | 2009 | |
| S12.11 Differential inhibition of energy-producing pathways of hepg2 cells by 3-bromopyruvate | 10.1016/j.bbabio.2008.05.306 | 2008 |
| Cold acclimation effect on oxygen consumption in isolated mitochondria and permeabilized fibers of goldfish skeletal muscle | 2008 | |
| Characterization of the hexokinase activity in the White skeletal muscle from goldfish (carassius auratus) | 2008 | |
| Efeito da aclimatação ao frio sobre o consumo de O2 em mitocôndrias isoladas e fibras permeabilizadas de músculo esquelético de peixes dourados (Carassius auratus L.) | 2008 | |
| Caracterização de uma Hexocinase tipo II em músculo esquelético de Carassius auratus: efeito da aclimatação ao frio. | 2007 | |
| Caracterização de uma Hexocinase tipo II em músculo esquelético de Carassius auratus: efeito da aclimatação ao frio. | 2007 | |
| Ca2+ transport and heat released by the sarcoendoplasmic reticulum Ca2+-ATPase of acclimated Goldfish (Carassius auratus). | 2007 | |
| Heart-specific overexpression of human type 2 iodothyronine deiodinase increases myocardial glucose and lipid metabolism in mice | 2006 | |
| Type 2 iodothyronine (D2) is an essential component of brown adipocyte differentiation program. | 2005 | |
| Abeta inhibits mitochondrial-bound hexokinase: Implications for impairment of brain energy metabolism in Alzheimer's disease | 2005 | |
| Mitocondrial creatine kinase activity prevents reactive oxygen species generation: pivotal role of mitochondrial kinase ADP re-cycling as an antioxidant defense. | 2005 | |
| Hexokinase as a Metabolic Target in the Hepatomas Treatment: Use 3-Bromopyruvate as a Inhbitor of Glucose Phosphorylation. Is the Main Action Mechanism? | 2004 | |
| Glycolitic Enzymes associated to Rat Brain Synaptic Vesicles Control the ATP Synthesis for the V0V1-ATPase: Effect of therapeutic Hypothermia. | 2004 | |
| Fuctional Role of Mitochondrial Bound Hexokinase Activity: Steady State ADP Formation As A Regulatory Mechanism of Membrane Potencial and ROS Generation in Mitochondrial | 2004 | |
| Functional role of mitochondria bound hexokinase activity: Steady-state ADP formation as a regulatory mechanism of membrane potential and reactive oxygen species generation in mitochondria. | 2004 | |
| Functional Role of Mitochondrial Bound Hexokinase Activity: Steady State ADP Formation As A Regulatory Mechanism of Membrane Potencial in Mitochondria. | 2004 | |
| Intracellular effect of triiodothyronine on the energy expenditure. | 2004 | |
| A new model for proton pumping in animal cells: the role of pyrophosphate | 2004 | |
| Ca2+ uptake in maize seedling roots (Zea mays L.) treated or not with CaCl2. | 2003 | |
| Uncoupled ATPase activity and heat production by the sarcoplasmic reticulum Ca2+-ATPAse in hyperthyroidism. | 2003 | |
| Ca2+ transport mediated by the H+/Ca2+ antiporter of maize root cells. | 2002 | |
| Interconversion of chemical and osmotic energy into heat by the pyrophosphatase of maize roots tonoplast. | 2002 | |
| Atividade da hexokinase em coleóptilos: modulação por hormônios de planta. | 2002 | |
| H+-PPases: Novo modelo de acidificação de compartimentos em insetos. | 2002 | |
| Efeito do exercício aeróbico prévio sobre a atividade da SDH e da LDH no músculo esquelético de ratos infartados. | 2002 | |
| Subcellular distribution and kinetic properties of cytosolic and non-cytosolic hexokinases in maize seedling roots: implications for hexose phosphorylation. | 2001 | |
| Effect of the fatty acids in the heat production by vacuolar H+-PP(i)ase of maize roots. | 2001 | |
| Effect of the fatty acids in the heat production by vacuolar H+-PP(i)ase of maize roots. | 2001 | |
| Hexokinase activities in maize coleoptiles: modulation by plant growth hormones. | 2001 | |
| Distribution of fructokinases and hexokinases in maize (Zea mays L.): correlation with the hexose levels in plant tissues. | 2001 | |
| Characterization of endocytic vesicles-associated enzymes from Rhodnius Prolixus. | 2001 | |
| Characterization of endocytic vesicles-associated enzymes from Rhodnius Prolixus. | 2001 | |
| Heat production by plasma membrane H+ ATPase and V0V1- H+ ATPase of maize roots: Effect of the pH. | 2000 | |
| Partial characterization of UDP-glucose transporter in Golgi vesicles of maize roots. | 2000 | |
| Heat production by PM-H+ ATPase and V0V1- H+ ATPase of maize roots: Effect of the pH. | 2000 | |
| Hexokinase and its involvement on the cellulose biosynthesis pathway in main roots of maize (Zea mays L.). | 1999 | |
| Glucose and fructose phosphorylation in maize (Zea mays L.) plants. | 1999 | |
| Fosforilação de glicose e frutose em raíz de milho (Zea mays L.) | 1999 | |
| A hexoquinase e seu papel na biossíntese de celulose em raízes primárias de milho. | 1999 | |
| Glucose and fructose phosphorylation in maize seeds: distinct cellular sites for hexoses phosphorylation. | 1999 | |
| Effect of sugars on the growth of primary roots of maize (Zea mays L.) seedling. | 1998 | |
| Glucokinase and fructokinase in maize seeds: distinct cellular sites for hexoses phosphorylation. | 1998 | |
| Glicoquinase e frutoquinase em sementes de milho: distintos sítos celulares para fosforilação de hexoses. | 1998 | |
| Hexokinase regulates the NDP-sugar synthesis im maize roots. | 1997 | |
| A síntese de NDP-açúcar em raíz de milho é regulada pela hexoquinase. | 1997 | |
| Maize hexokinase is activated by NDP-sugars. | 1996 | |
| Subcellular and developmental distribution of hexokinase activities in maize seedlings. | 1996 | |
| Different Hexokinase activities induced by water during maize seeds germination. | 1995 |