Paulo de Assis Melo

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Campus de Macaé

Unidade:

Direção Geral/Macaé

Departamento:

Docentes do Campus UFRJ/Macaé

ORCID:

https://orcid.org/0000-0003-1250-6933


Formação:

  • OKLAHOMA STATE UNIVERSITY

    | Pós-Doutorado | 1994 - 1996

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1988 - 1992

  • Universidade Federal do Rio de Janeiro

    Farmacologia e Terapeutica Experimental | Mestrado | 1978 - 1983

  • Universidade Federal do Rio de Janeiro

    Farmacologia e Terapeutica Experimental | Especialização | 1977 - 1978

  • Universidade do Estado do Rio de Janeiro

    | Especialização - Residência medica | 1977 - 1978

  • FACULDADE DE MEDICINA DE CAMPOS

    MEDICINA | Graduação | 1971 - 1976
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:

(63.92% artigos com DOI)

Titulo DOI Ano
The search for an antiviral lead molecule to combat the neglected emerging Oropouche virus 10.1016/j.crmicr.2024.100238 2024
Monoclonal-Based Antivenomics Reveals Conserved Neutralizing Epitopes in Type I PLA2 Molecules from Coral Snakes 10.3390/toxins15010015 2023
Heparin prevents the cytotoxic activity of Bothrops jararacussu and Apis mellifera venoms in renal cells 10.1016/j.toxicon.2022.107011 2022
A Novel Apilic Antivenom to Treat Massive, Africanized Honeybee Attacks: A Preclinical Study from the Lethality to Some Biochemical and Pharmacological Activities Neutralization 10.3390/toxins13010030 2021
Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation 10.3389/fimmu.2021.651740 2021
Phytochemical composition, antisnake venom and antibacterial activities of ethanolic extract of Aegiphila integrifolia (Jacq) Moldenke leaves 10.1016/j.toxicon.2021.05.004 2021
DOXYCYCLINE TREATMENT REESTABLISHES RENAL FUNCTION OF WISTAR RATS IN EXPERIMENTAL ENVENOMATION WITH Bothrops jararacussu VENOM 10.1016/j.toxicon.2021.05.008 2021
REVISITING THE ACUTE KIDNEY INJURY IN WISTAR RATS EXPERIMENTALLY ENVENOMATED WITY Bothrops jararacussu VENOM. 10.1016/j.toxicon.2021.06.004 2021
Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms 10.1371/journal.pone.0211229 2019
Protective outcomes of low-dose doxycycline on renal function of Wistar rats subjected to acute ischemia/reperfusion injury 10.1016/j.bbadis.2017.10.005 2018
True or false coral snake: is it worth the risk? A Micrurus corallinus case report 10.1186/s40409-018-0148-9 2018
Blockade of ATP P2X7 receptor enhances ischiatic nerve regeneration in mice following a crush injury 10.1016/j.brainres.2017.05.025 2017
Occurrence of sulfated fucose branches in fucosylated chondroitin sulfate are essential for the polysaccharide effect preventing muscle damage induced by toxins and crude venom from Bothrops jararacussu snake 10.1016/j.toxicon.2015.02.010 2015
Pattern of inflammatory response to Loxosceles intermedia venom in distinct mouse strains: A key element to understand skin lesions and dermonecrosis by poisoning 10.1016/j.toxicon.2015.01.008 2015
A comparison of virulence patterns and in vivo fitness between hospital- and community-acquired methicillin-resistant Staphylococcus aureus related to the USA400 clone 10.1007/s10096-014-2253-1 2015
Different effects of myotoxins bothropstoxin-I and II from Bothrops snake venom on cation transport ATPases from murine fast twitch skeletal muscle 10.1016/j.toxicon.2015.06.009 2015
Purinergic P2Y12 Receptor Activation in Eosinophils and the Schistosomal Host Response 10.1371/journal.pone.0139805 2015
MEDICINAL PLANTS IN THE TREATMENT OF SNAKEBITE: A TECHNOLOGICAL FORECASTING 10.7198/s2237-0722201400020017 2014
Counteraction of Bothrops snake venoms by Combretum leprosum root extract and arjunolic acid 10.1016/j.jep.2014.05.056 2014
Abarema cochliacarpos Extract Decreases the Inflammatory Process and Skeletal Muscle Injury Induced by Bothrops leucurus Venom 10.1155/2014/820761 2014
Crovirin, a Snake Venom Cysteine-Rich Secretory Protein (CRISP) with Promising Activity against Trypanosomes and Leishmania 10.1371/journal.pntd.0003252 2014
Dexamethasone Antagonizes the in vivo Myotoxic and Inflammatory Effects of Bothrops Venoms 10.1016/j.toxicon.2013.01.023 2013
Neutralization of Apis mellifera Bee Venom Activities by Suramin 10.1016/j.toxicon.2013.02.007 2013
Double gene therapy with granulocyte colony-stimulating factor and vascular endothelial growth factor acts synergistically to improve nerve regeneration and functional outcome after sciatic nerve injury in mice 10.1016/j.neuroscience.2012.10.025 2013
Antiophidic activity of the extract of the Amazon plant Humirianthera ampla and constituents 10.1016/j.jep.2012.10.033 2013
Pulsed ultrasound therapy accelerates the recovery of skeletal muscle damage induced by Bothrops jararacussu venom 10.1590/S0100-879X2012007500033 2012
Mesenchymal Stem Cells in a Polycaprolactone Conduit Promote Sciatic Nerve Regeneration and Sensory Neuron Survival after Nerve Injury 10.1089/ten.tea.2011.0496 2012
Effect of Crotalus viridis viridis snake venom on the ultrastructure and intracellular survival of Trypanosoma cruzi 10.1017/S0031182010000958 2011
Enhancement of sciatic-nerve regeneration after VEGF gene therapy 10.1111/j.1365-2990.2011.01159.x 2011
Tongue angioedema : Antagonist response of anti-inflammatory drugs 10.3109/15563650.2011.564587 2011
Ability of a synthetic coumestan to antagonize Bothrops snake venom activities 10.1016/j.toxicon.2009.09.021 2010
Effect of heparin treatment on the expression and activity of different ion-motive P-type ATPase isoforms from mouse extensor digitorum longus muscle during degeneration and regeneration after Bothrops jararacussu venom injection 10.1016/j.toxicon.2009.06.032 2010
Gestão das inovações incrementais, o caso Omeprazola 10.1590/s0100-40422010000400044 2010
Mesenchymal stem cells into polycaprolactone conduit enhance median nerve regeneration, prevent dropping of creatine fosfokinase muscle levels and improve functional recovery in mice 10.1016/j.neuroscience.2010.08.042 2010
Effects of Probiotic Supplementation on Markers of Acute Pancreatitis in Rats 10.1016/j.curtheres.2009.04.004 2009
Antilonomic Effects of Brazilian Brown Seaweed Extracts 2009
Structural and Pharmacological Features of Phospholipases A2 from Snake Venoms 10.2174/092986609788923365 2009
Ability of suramin to antagonize the cardiotoxic and some enzymatic activities of Bothrops jararacussu venom. 10.1016/j.toxicon.2007.07.002 2008
Biochemical and Structural Investigations of Bothropstoxin-II, a Myotoxic Asp49 Phospholipase A2 from Bothrops jararacussu Venom 10.2174/092986608785849245 2008
Increase of the cytotoxic effect of Bothrops jararacussu venom on mouse extensor digitorum longus and soleus by potassium channel blockers and by Naþ/Kþ-ATPase inhibition 10.1016/j.toxicon.2008.07.003 2008
Interfacial surface charge and free accessibility to the PLA2-active site-like region are essential requirements for the activity of Lys49 PLA2 homologues 10.1016/j.toxicon.2006.10.011 2007
Evaluation of three Brazilian antivenom ability to antagonize myonecrosis and hemorrhage induced by Bothrops snake venoms in a mouse model 10.1016/j.toxicon.2007.03.010 2007
Suramin counteracts the haemostatic disturbances produced by Bothrops jararaca snake venom 10.1016/j.toxicon.2007.01.002 2007
Inhibition of Myotoxic Activity of Myotoxin II by the Anti-trypanosomal Drug Suramin 10.1016/j.jmb.2005.04.072 2005
Pulmonary mechanics and lung histology in acute lung injury induced by Bothrops jararaca venom 10.1016/j.resp.2003.10.002 2004
Membrane depolarization is the initial action of crotoxin on isolated murine skeletal muscle 10.1016/j.toxicon.2003.10.029 2004
Synthesis and pharmacological evaluation of prenylated and benzylated pterocarpans against snake venom 10.1016/j.bmcl.2003.10.044 2004
Crystallization and preliminary X-ray diffraction analysis of suramin, a highly charged polysulfonated napthylurea, complexed with a myotoxic PLA from venom 10.1016/j.bbapap.2004.08.009 2004
Suramin interaction with human ?-thrombin: inhibitory effects and binding studies 10.1016/j.biocel.2004.03.007 2004
Myotoxicity induced by an acidic Asp-49 phospholipase A2 isolated from Lachesis muta snake venom 10.1016/s1357-2725(03)00129-8 2003
Antagonism of myotoxic and paralyzing activities of bothropstoxin-I by suramin 10.1016/S0041-0101(03)00166-1 2003
Effect of denervation on the myotoxicity of Bothrops jararacussu venom on the fast-and-slow twitch muscle in mice 2003
Evaluation of cutaneous lesions experimentally induced by Bothrops jararaca snake venom 2003
Natural Inhibitors of Toxins and Snake Venoms 2003
Mice skeletal muscle regeneration after being damaged by Bothrops jararacussu venom:effect of heparin 2003
Inhibition of myotoxic and phospholipase activities of crotoxin by suramin 2003
Antivenom effect of a new synthetic coumestan analag of wedeloactone 2003
Calcium distribuition on muscular fibers exposed to Bothrops jararacussu Venom 2003
Effect of Heparin and Antivenom on skeletal muscle damage produced by Bothrops jararacussu venom 2002
Effect of suramin on myotoxicity of some crotalid snake venoms 10.1590/S0100-879X2002000600013 2002
Effect of perimuscular injection of Bothrops jararacussu venom on plasma creatine kinase levels in mice: influence of dose and volume 10.1590/s0100-879x2002001000018 2002
Synthesis and preliminary pharmacological evaluation of new (±) 1,4-naphthoquinones structurally related to lapachol 10.1016/S0968-0896(02)00100-1 2002
Antagonism of the myotoxic crotalid venoms by different polyanions 2002
Synthesis and preliminary pharmacological evaluation of coumestans with different patterns of oxygenation 10.1016/s0960-894x(00)00621-1 2001
A novel thienylhydrazone(2-thienylidene)3,4- methylenedioxybenzoylhydrazine, increases inotropism and decreases fatigue of skeletal muscle 2001
Efeito Neutralizante de Casearia sylvestris Sw. Sobre a Atividade Miotóxica do Veneno de Bothrops jararacussu 2001
Effect of heparin on mice muscle regeneration after being damaged by Bothrops venoms: An ultrastructural study 2001
Myotoxic activity of an acidic phospholipase A2 isolated from Lachesis muta (Buschmaster) snake venom 10.1016/S0041-0101(99)00208-1 2000
Chronic Ulceration of the Leg Secondary to a Snake Bite Complicated by Scamous Cell Cancer 10.1007/s002560050613 2000
Antagonism of myotoxic phospholipase A2 2000
Ability of wedelolactone, heparin, and para-bromophenacyl bromide to antagonize the myotoxic effects of two crotaline venoms and their PLA2 myotoxins 10.1016/s0041-0101(98)00183-4 1999
Effect of treatment with heparin and antivenom in regeneration of mice's skeletal muscle damage with Bothrops jararacussu venom. 1999
Pulmonary effects of snake venom-induced inflammation of mouse lung 1999
Heparin inhibits acute pancreatitis induced by thaurocolic acid in rats 1998
Efeitos pulmonares da administração de veneno de cobra em camundongos 1998
Substances that antagonize the myotoxic effect of crotlid snake venoms 1997
Different sensitivity of white and red skeletal muscles to the myotoxic components of snake venoms 1996
Effects of crotoxin on murine omohyoid muscle: spectrofluorimetry,fluorescence imaging, and creatine kinase release 1996
Different sensitivity of fast- and slow-twitch muscles to some snake venoms and myotoxins 10.1016/0041-0101(96)00015-3 1996
Inhibition of the Myotoxic and Hemorrhagic Effect of Crotalidae Venoms by Eclipta Prostrata (Asteraceae) Extracts and Constituents 10.1016/0041-0101(94)90207-0 1994
Antagonism of the Myotoxic Effects of Bothrops Jararacussu Venom and Bothropstoxin by Polyanions 10.1016/0041-0101(93)90146-A 1993
Effects of Calcium entry blockers on agonist-induced tensions of Guinea pig Trachealis muscle bathed in low calcium solution 1993
Antiproteolytic and antiphospholipasic activity of wedelolactone 1993
Comparative Pharmacokinetics Of Different Oral Nifedipine Preparations in Health Brazilian Volunteers. 1992
Pharmacokinetics Of Oral Ciprofloxacin In Health Young Brazilian Subjects. 1990
Antagonism of the myotoxic and hemorrhagic effects of crotalidae venoms by Eclipta prostrata extracts and constituents. 1990
Neutralization Of Lethal And Myotoxic Activities Of South American Rattlesnake Venom By Extracts And Constituents Of The Plant Eclipta Prostrata (Asteraceae). 10.1016/0041-0101(89)90151-7 1989
Release Of Creatine Kinase From Skeletal Muscle By Bothrops Venoms: Heparin Potentiation Of Inhibition By Antivenim. 1988
Release Of Sarcoplasmic Enzymes From Skeletal Muscle By Bothrops Jararacussu Venom: Antagonism By Heparin And By The Serum Of South American Marsupials 10.1016/0041-0101(88)90140-7 1988
Antagonism of the myotoxic and hemorrhagic effects of Bothrops venoms by extracts of Eclipta prostrata, Asteraceae and their components 1988
Interation Of Bothrops Venoms And Antivenin on the Release Of Creatine Kinase From Skeletal Muscle. 1987
Inibição pelo soro de marsupiais dos efeitos dos venenos botrópicos ns liberação de enzimas sarcoplasmáticas de musculos esqueléticos 1987
Estudo da Associacão Nitrato e Xantina No Tratamento da Crise Hipertensiva 1986
Effects of polyanions on the stimulation of sarcoplasmic enzime release induced by Bothrops jararacussu venom. 1985
Effects of denervation on the release of sarcoplasmic enzymes from mammalian muscles 1985
Intracebroventricular 6-Hydroxidopamine (6-OHDA) and 5,7 Dihidroxytryptamine 1984
Effect of Intracisternal and Intraventricular Injection of Serotonin, Dopamin and their precursor on Seizure Thresold to Lidocaine 1982
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Anti-Apis serum failed to antagonize cytotoxicity induced by Apis mellifera venom in vitro 2016
Doxycycline-attenuation of ER-stress components: GRP78-eIF2 α is an additional mechanism to metalloproteinase inhibition in kidney protection after ischemia-reperfusion 2016
Effects of polyanions and antibotropic serum on some activities of Bothrops leucurus venom 2016
Acute cutaneous lesions induced by Bothrops jararacussu snake venom in mice: Antagonism by heparin 2016
N-acylhydrazone derivative (LASSBio-785) antagonizes Apis mellifera venom activity in mice 2016
Basis of Anesthesia and Pain Management in Animal Experimentation 2016
Bothropstoxin-I (BTHTX-I) And Polylysine Can Potentiate Bothropstoxin-ii (BTHTX ii) Activity and They are Antagonized by Fusosylated Chondroitin Sulfate 2016
Antagonism of in vitro and in vivo activities of Apis mellifera venom by antiapilic serum 2016
Brazilian monospecific anti-crotalic serum does not neutralize the systemic inflammatory response syndrome (sirs) and the disseminated intravascular coagulation (dic) induced by crotalus spp. snake venom from Bahia, Brazil 2016
Heparin protect acute cutaneous lesions induced by Bothrops jararacussu snake venom in mice 2016
26-19-8: Cytotoxicity of Apis mellifera Bee Venom: Pharmacological interventions and treatment. 2015
28-3-11Monoclonal basic antivenomics and biological activities revealing conserved neutralizing epitopes across Elapidae family 2015
Neutralization of in vitro and in vivo activities of Apis mellifera venom by antiapilic serum 2015
EFFECTS OF POLYANIONS ON SOME ACTIVITIES OF Bothrops leucurus VENOM 2015
Cytotoxicity of Apis mellifera Bee Venom: Pharmacological interventions and Treatment 2015
Bothropstoxin-I (BthTX-I) and polylysine can potentiate Bothropstoxin-II (BthTX-II) phospholipase activity in vitro and they are antagonized by fucosylated chondroitin sulfate. In: XIII Congress of the Brazilian Society of Toxinology, 2015
Use of Eclipta prostrata extract prevents tissue damage induced by snake venoms in horses during antiophidic serum production 2014
Capsaicin and Eugenol decrease some activities of bee venom in mice 2014
Ability of heparin to antagonize cytotoxic and enzymatic activies of bee venom 2014
Fucose moieties is essential for the ability of fucosilated chondroitin sulfate to inhibit muscle damage induced by toxins from Bothrops jararacussu snake 2014
Neutralization of Bothrops Snake Venoms from Ecuador by Antibothropic Antivenom Manufactured by Instituto Vital Brazil 2014
Neutralization of Bothrops Snake Venoms from Ecuador by Antibothropic Antivenom Manufactured by Instituto Vital Brazil 2014
Effects of polyanions on some activities of Bothrops leucurus venom 2014
Treatment with doxycycline prevents the renal function impairment in rats subjected to kidney ischemia-reperfusion 2014
Heparin antagonize the cytotoxic and some enzymatic activities of Apis mellifera bee venom El-kik, C.Z.;Gaban, 2014
Microcystin-LR is cardiotoxic on mouse isolated hearts. 2013
The Effect of Loxosceles intermedia Venom in Mice Skin 2013
Fucose moieties is essential for the ability of fucosylated chondroitin sulfate to inhibit muscle damage induced by toxins and crude venom from Bothrops jararacussu snake. 2013
Cytotoxic effect of Bothrops jararacussu and Apis mellifera venom in renal tubular cells (llc-pk1) and antagonism by polyanions 2013
Fucose moieties is essencial for the ability of Fucosylated Chondroitin Sulfate to inhibit muscle damage induced by toxins and crude venom from Bothrops jararacussu snake 2013
Antiophidic activity of the new synthetic lapachol analogues 2013
Microcystin-LR is cardiotoxic on mouse isolated hearts 2013
Study of the cytotoxic effect of Bothrops jararacussu and Apis mellifera venom in renal tubular cells (llc-pk1) and antagonism by polyanions 2013
Capsaicin or Eugenol treatment protect mice against some activities of Apis meliffera bee venom 2013
Treatment with heparin improves regeneration of cutaneous lesions experimentally induced by Bothrops jararacussu snake venom. 2013
Study of the cytotoxic effect of Bothrops jararacussu and Apis mellifera venom in renal tubular cells (llc-pk1) and antagonism by polyanions 2013
. Fucose moieties are essential for the ability of fucosylated chondroitin sulfate to inhibit muscle damage induced by Bothrops jararacussu venom 2012
Cytotoxic effect of Bothropsjararacussu venom in renal tubular cells (LLC-PK1) and antagonism by heparin 2012
Different effects of bothropstoxin I and II on NA+/K+-ATPase and CA2+-ATPase from type serca of murine fasttwitch muscle extensor digitorum longus 2012
Synthesis of lapachol analogues using Suzuki-Miyaura coupling methodology and evaluation of the antiophidic activity 2012
Cardiotoxic effects of microcystin?LR in mouse isolated hearts. Siqueira-Lece F 2012
Study of inflammatory and myotoxic effects of Bothrops venoms: Effects of dexamethasone and Eclipta prostrata (L.) 2012
Evaluation of the Antiophidic Activity of Lapachol and Synthetic Analogues, 2012
Ability of Polyanions to Antagonize the Cardiotoxic Effect of the Bothrops jararacussu Venom, 2012
Fucose Moieties Are Essential for the Ability of Fucosylated Chondroitin Sulfate to Inhibit Muscle Damage Induced by Bothrops jararacussu Venom 2012
Dexamethasone Antagonizes the Myotoxic and Inflammatory Effect of Bothrops Venoms 2012
Evaluation of Cardiotoxic Effects of Microcystin-LR in Mouse Isolated Hearts 2012
DEXAMETHASONE DID NOT PROTECT THE MOUSE PHRENIC-DIAPHRAGM PREPARATION FROM THE CYTOTOXIC EFFECT OF BOTHROPS JARARACUSSU VENOM 2011
MYOTOXICITY OF BOTHROPSTOXINS I AND II IN MOUSE FAST- AND SLOW-TWITCH MUSCLES. 2011
ANTAGONISM OF THE CARDIOTOXIC EFFECT OF ISOLATED TOXINS FROM B. JARARACUSSU VENOM BY SURAMIN 2011
FUCOSE MOIETIES IS ESSENTIAL FOR THE ABILITY OF FUCOSYLATED CHONDROITIN SULFATE TO INHIBIT MUSCLE DAMAGE INDUCED BY BOTHROPS JARARACUSSU VENOM 2011
EFFECT OF MICROCYSTIN?LR IN RAT ISOLATED HEARTS 2011
EFFECT OF MYOTOXINS BOTHROPSTOXIN I AND II ON CATION TRANSPORT ATPASES OF MURINE FAST-TWITCH MUSCLE EXTENSOR DIGITORUM LONGUS 2011
STRUCTURE-ACTIVITY OF LB-294 DERIVATIVES ON CANNABINOID AND VANILLOID RECEPTORS 2011
ABILITY OF FUCOSYLATED CHONDROITIN SULFATE TO INHIBIT MUSCLE DAMAGE INDUCED BY Bothrops jararacussu CRUDE SNAKE 2010
ABILITY OF SURAMIN TO ANTAGONIZE PERMEABILITY ALTERATIONS INDUCED BY HONEY BEE VENOM 2010
ADP effect on skin wound healing on diabetic mice 2010
ANTIOPHIDIC ACTIVITY OF THE AMAZON PLANT Humirianthera ampla AND ITS COMPOUNDS LUPEOL AND SITOSTEROL 2010
Biological effects of a cystein-rich secretory protein isolated from the Crotalus viridis viridis snake venom on Trypanosoma cruzi trypomastigotes 2010
CARDIOTOXIC EFFECT OF Bothrops asper VENOM: ANTAGONISM BY HEPARIN 2010
DEXTRAN SULFATE PROTECTED ISOLATED RAT HEART FROM THE CARDIOTOXIC ACTIVITY OF Bothrops jararacussu VENOM 2010
Effects of therapeutic ultrasound on mouse skeletal muscle damaged by Bothrops jararacussu snake venom 2010
PULSED THERAPEUTIC ULTRASOUND EFFECTS ON SKELETAL MUSCLE DAMAGE INDUCED BY Bothrops jararacussu SNAKE VENOM 2010
Ability of a fucosylated chondroitin sulfate to prevent muscle damage induced by Bothrops jararacussu snake venom 2009
Evaluation of the antiophidic activity of the extract of an amazon plant named Humirianthera ampla 2009
Effects of suramin and the compound LASSBio 448 on some activities of Bothrops leucurus venom 2009
Heparin inhibits the myotoxic effect of apis mellifera crude venom 2009
Cardiotoxic effect of bothrops moojeni venom and fractions 2009
Ability of heparin to antagonize the cardiotoxic effect of the Bothrops jararacussu venom and its myotoxins 2009
Study of suramin na inflammatory response and citotoxicity of Bothrops venoms 2009
Ability of suramin to antagonize hemodinamic alterations induced by honey bee venom 2009
Habilidade da suramina em antagonizar as atividades citotóxicas da melitina 2009
Inibição de atividades do veneno de Bothrops leucurus pela suramina e substancias planejadass(LASSBio 448) 2009
Avaliação da administração crônica de Trifolium pratense L. em mama de ratas ooforectomizadas 2008
Avaliação do tipo de fibra do músculo esquelético de camundongo após lesão por veneno de Bothrops Jararacussu e tratamento com heparina 2008
Combretum leprosum fruit extract inhibits hemostasis alterations induced by Bothrops snake venom 2008
Efeito miotóxico do veneno de Agkistrodon contortrix laticinctus na preparação frênico-diafragma de camundongo: inibição pela suramina 2008
Estudo da atividade antiofídica do extrato etanólico e da planta Humirianthera ampla 2008
Habilidade da suramina em inibir a resposta inflamatória induzida pelo veneno de Apis mellifera 2008
Habilidade da suramina em inibir a resposta inflamatória induzida pelo veneno de Apis mellifera 2008
Heparin antagonize cardiotoxic effect of Bothops jararacussu venom 2008
Influence of fast-twitch skeletal muscle degeneration/ regeneration induced by Bothrops jararacussu venom and heparin treatment on the Na+/K-ATPase and Ca-ATPase activity and protein expression 2008
Inibição de atividades do veneno de Bothrops leucurus pela suramina e substâncias planejadas (LASSBio 448). 2008
EFEITO DO VENENO Bothrops jararacussu NA ATIVIDADE E EXPRESSÃO DAS ISOFORMAS DA BOMBA DE CA2+ SERCA1 E SERCA2 EM MÚSCULO EDL DE CAMUNDONGOS: EFEITO DA HEPARINA 2007
HABILIDADE DA SURAMINA EM ANTAGONIZAR AS ALTERAÇÕES HEMODINÂMICAS INDUZIDAS PELO VENENO DE Apis mellifera 2007
ESTUDO DO EFEITO MIOTÓXICO DO VENENO DE Agkistrodon contortrix laticinctus NA PREPARAÇÃO FRÊNICO-DIAFRAGMA DE CAMUNDONGO: INIBIÇÃO PELA SURAMINA 2007
EFFECT OF DENERVATION AND LOCAL ANESTHETIC AGENTS ON TONGUE AND SKIN EDEMA INDUCED BY DIEFFENBACHIA PICTA SCHOTT 2007
ESTUDO DO EFEITO ANTIOFÍDICO DE EXTRATO DE Humirianthera ampla 2007
EVALUATION OF ANTIOFIDIC ACTIVITY OF COMBRETUM LEPROSUM MART FRUIT EXTRACT 2007
INHIBITION OF BOTHROPS JARARACUSSU ACTIVITIES BY COMBRETUM LEPROSUM MART FRUIT EXTRACT AND ITS ACTIVE COMPONENTS. 2007
ANTIMYOTOXIC EFFECTS OF SURAMIN AND POLYETHYLENE GLYCOL (PEG) AGAINST Agkistrodon contortrix laticinctus CRUDE VENOM AND ITS MYOTOXIN ON MICE ISOLATED SKELETAL MUSCLE AND DIAPHRAGM NEUROMUSCULAR PREPARATION 2007
ABILITY OF A SYNTHETIC COUMESTAN NAMED LQB93 TO PROTECT AGAINST THE CARDIOTOXIC EFFECT OF Bothrops jararacussu VENOM 2007
Ability of Suramin to Antagonize Myotoxic and Phospholipase Activities of Bee Venom 2006
Antimyotoxic Effects of Suramin and Polyethylene Glycol (PEG) Against Agkistrodon Contortrix Laticinctus Crude Venom and its Myotoxin. 2006
Ability of a Synthetic Coumestan Named LQB93 to Antagonize Some Bothrops Snake Venoms Activity. 2006
Dexamethasone Shows In Vivo but not In Vitro Antimyotoxic Effect Against Bothrops Jararacussu Snake Venom. 2006
Improvement of Mouse Skeletal Muscle Regeneration by Heparin after Lesion Induced by Bothrops Jararacussu Venom. 2006
Mouse Extensor Digitorum Longus and Soleus have a Different Sensitivity to Some Snake Venoms Myotoxicity. 2006
Antagonism of the Cardiotoxic Effect of Bothrops Jararacussu by Suramin. 2006
Effect of Eugenol and Local Anesthetic Agents on Tongue and Skin Edema Induced by Dieffenbachia Picta Schott in Mice. 2006
Ability of a synthetic coumestan named LQB93 to antagonize some bothrops snake venom activity 2005
Study of the cardiotoxic activity of Bothrops jararacussu venom on different Bullfrog heart assays and the antagonism by suramin 2005
Dexamethasone increases the antimyotoxic effects of Eclipta prostrata against Bothrops jararacussu snake venom 2005
Study of the cardiotoxic effects of B. jararacussu venom in vitro and in vivo: antagonism by wedelolactone and suramin 2005
Effect of denervation and local anesthetic agents on the edema induced by Dienffenbachia picta 2005
Evaluation of the myotoxic, proteolytic and phopholipase activities of Dienffenbachia picta 2005
Evaluation of the antiophidic activity of Caombretum leprosum fruit extract 2005
Estudo do efeito miotóxico do veneno de Agkistrodon contortrix laticinctus na preparação frênico-diafrágma de camundongo: Inibição pela suramina 2005
Efeito da associação do extrato aquoso de Eclipta prostrata (asteraceae) e dexametasona na lesão local - edema e miotoxicidade - induzida por injeção do veneno de serpentes do gênero Bothrops 2004
Avaliação da atividade antiofídica do cipó ambé 2004
What can we do in the Bothrops snakebite accident? 2004
Binding site of suramin in k49 PLA2 s 2004
Evaluation of the antiophidic activities of three Brazilian polyvalent antivenin 2004
Cardiotoxic activity of Bothrops jararacussu venom and the inhibition of by suramin 2004
Heparin improves the muscle regeneration after damage by Bothrops jararacussu venom. 2004
Myotoxic effect of different venom on mouse skeletal muscle 2004
Efeito antiofídico do edunol e seus derivados sintéticos 2004
Diferentes atividades miotóxicas de peçonhas em músculos esqueléticos de camundongos 2004
Antiophidic effect of PCALC-36, a a synthetic coumestan 2004
Heparin improves skeletal muscle regeneration 2004
Angiogênese experimental na pele de camundongos induzida pelo veneno da serpente Bothrops 2003
Antagonism of myotoxic and paralysing activities of bothropstoxin-I (Bthtx-I) by suraminb on mouse neuromuscular preparations 2003
Efeito antiofídico de cumestano sintético análogo da wedelolactona com diferente padrão de oxigenação 2003
Heparin improves mouse muscle regeneration after being damaged by bothrops jararacussu venom 2003
Heparin improve the muscle regeneration after damage by snake venom 2003
Myotoxicity of Bothrops jararacussu venom on mouse fast- and slow-twich muscle following denervation 2003
Myotoxicity of Bothrops jararacussu snake venom on mouse fast-and slow-twitch muscle following denervation 2003
Natural inhibitors of toxins and snake venoms 2003
Synthesis and pharmacological evaluation of prenylated and benzylated pterocarpans against snake venoms. 2003
Síntese e avaliação farmacológica de novas 1;4-naftoquinonas estruturalmente relacionadas ao lapachol 2002
Antagonism of myotoxic effect of crotalid venoms by diferent polyanions. 2002
Inibição da miotoxicidade e atividade fosfolipase da crotoxina pelo suramin. 2002
Efeito antiofídico de novo cumestano sintético análogo da wedelolactona com diferente padrão de oxigenação. 2002
Heparina induz regeneração muscular após lesão por veneno de Bothrops jararacussu 2002
Toxicological studies of Lassbio 294, a new thienylacylhydrazone positive inotropic agent. 2002
Mice skeletal muscle regeneration after being damaged by Bothrops jararacussu venom: effect of heparin. 2002
Effect of denervation on the myotoxicity of Bothrops jararacussu venom on the fast- and slow-twitch muscles in mice. 2002
Antivenom effect of a new synthetic coumestan analog of wedelolactone 2002
Inhibition of myotoxic and phospholipase activity of crotoxin by suramin 2002
Avaliação Morfológica e Evolutiva de Lesões cutanes induzidas experimentalmente pelo veneno de da Serpente Bothrops jararaca 2002
Heterogeneity of three Brazilian antibothropic antivenin in antagonizin Bothops venoms 2001
Pharmacological evaluation of antimyotoxic new coumestans with different patterns of oxygenation. 2001
Effect of suramin on myotoxicity of different crotalid snake venoms from North and South America in mice 2001
Ultrastructural analysis of the effect of heparin on mice muscle regeneration after being damaged by Bothrops venom 2001
Efect of dose and volume of an intramuscular injection of Bothrops jararacussu venom on plasma creatine kinase activity in mice. 2001
A novel thienylhydrazone increases inotropism and decreases fatigue of skeletal muscle 2001
The novel thienylhydrazone LSSBio-294 increases inotropism and decreases fatigue of skeletal muscle 2001
Ultrastructural analysis of the effect of heparin on mice muscle regeneration after being damage by B. jararacussu venom 2001
Inhibition of the activity of Bothrops jararacussu venom by suramin 2000
Heparin induced mice muscle regeneration damaged by Bothrops jararacussu venom 2000
A phospholipase A2 myotoxic isoenzyme from Lachesis muta crude venom. 2000
Mice muscle regeneration after damage by Bothrops venom:effect of heparin. 2000
Inhibition of the proteolytic, PLA2 and myotoxicity activity of Bothrops jararacussu venom by suramin 2000
Inibição da atividade do veneno de Bothrops jararacussu por um polianion 2000
Avaliação da atividade antimiotóxica e antifosfolipase de coumestanos naturais e sintéticos 2000
Antisnake venom effect s of suramin 2000
Effect of heparin on mice muscle regeneration after damaged by Bothrops venom 2000
Snake venom phospholipase activity by using a turbidimetric assay 2000
Preliminary pharmacological evaluation of new coumestans with different patterns of oxygenation 2000
The pharmacology of toxins and environmental polluants: tools used to unveil physiopathological conditions. Organizado por Yasco Aracava 1a. aula The mechanism of cell damage by snake toxins and antagonism of their actions by natural and new synthetic molecules. 2000
Antivenin effect of Suramin 2000
Heterogeneity of three brazilian antivenin in antagonizing Bothrops venoms 2000
A phospholipase A2 myotoxic isoenzyme from Lachesis muta (Bushmaster) snake venom 2000
Effect of dose and volume of an intramuscular injection of Bothrops jararacussu venom on plasma creatine kinase in mice 2000
Estudo histopatológico, enzimático e do lavado broncoalveolar na pancreatite aguda induzida por caeruleina em camundongos. 1999
Estudo da atividade proteolítica do líquido ascítico de ratos com pancreatite aguda induzida pelo taurocolato de sódio. 1999
Avaliação histopatológica, enzimática e do lavado broncoalveolar na pancreatite aguda em camundongos. 1999
Atividade proteolítica do líquido ascítico de ratos com pancreatite aguda induzida pelo taurocolato de sódio 1999
LASSbio270 um novo composto com atividade anticonvulsivante 1999
Efeito da associação da Heparina ao Soro antibotrópico na regeneraçào de músculo esquelético lesado pelo veneno de Bothrops jararacussu. 1999
Estudo da atividade antiofídica de novo composto sintético denominado PCALC19. 1999
Heparin inhibits acute experimental pancreatitis induced by taurocholic acid in rats 1998
Antagonism of myotoxic phospholipase A2. 1998
Efeito da Heparina na regeneração do músculo esquelético lesado pelo veneno de Bothrops jararacussu. 1998
Atividade Proteolítica de venenos de Bothrops e antagonismo pela substância 726-52 1998
Avaliação da atividade hemorrágica de venenos de serpentes do gênero Bothrops em camundongos 1998
Characterization of an acidic myotoxin phospholipase A2 isolated from Lachesis muta snake venom 1998
Efeitos respiratórios da administração de venenos de cobra em camundongos 1998
Estudo do efeito da 726-52 na pancreatite aguda experimental. 1998
Tratamento da Pancreatite Aguda Experimental Com Polianiontes 1997
Modelo de Inflamacao Pulmonar Induzido Por Veneno de Bothops Jararaca 1997
Myotoxic Activity Of An Acid Phospholipase A2 From Lachelis Muta Snake 1997
Antagonism of the myotoxicity of North American Crotalid Venoms By Heparin And Wedelolactone. 1996
Ability Of Wedelolactone And Its Analogs To Antagonize Bothrops Venom Activity 1996
Different Sensitivity off White And Red Skeletal Muscles To The Myotoxic Components Of Snake Venoms. 1996
Effects Of Crotoxin On Murine Omohyoid Muscle; Spectrofluorimetry, Fluorescence Imaging And Creatine Kinase Release. 1996
Different sensitivity of white and red skeletal muscles to the myotoxic componernts of snake venoms. 1995
Effects of crotoxin on murine omohyoid muscle: spectrofluorimetry,fluorescence imaging and creatine kinase release 1995
Antiproteololytic And Antiphospholipsase Activities Of Wedelolactone. 1993
Effects Of Calcium Entry Blockers On Agonist-Induced Tensions Of Guinea Pig Trachealis Muscle Bathed In Low Calcium Solutions. 1993
Evidence of a complex formed by Bothropstoxin and heparin 1992
Farmacocinética comparativa de três apresentações de nifedipina. 1991
Farmacocinética comparativa de três apresentações de nifedipina. Vianna-Jorge, R.T. Sudo, P.A. Melo & G. Suarez-Kurtz VI Reunião Anual da FESBE - Caxambu, 1991, Resumos 9.13 1991
Efeito de polianiontes sulfatados na atividade miotóxica do veneno de B. jararacussu 1991
Antagonismo da atividade miotóxica do veneno de B. jararacussu por cumestanos 1990
Farmacocinética da ciprofloxacina em voluntários sadios 1990
Antagonism of the myotoxic and hemorrhagic effects of crotalidae venoms by Eclipta prostrata extracts and constituents 1990
Uso de método quantitativo para estudo da atividade hemorrágica do veneno de B. jararaca em camundongos 1989
Antagonism of the myotoxic and hemorrhagic effects of Bothrops venoms by extracts of Eclipta prostrata, Asteraceae 1988
Potencialização da atividade antimiotóxica do soro antibotrópico pela heparina 1988
Inibição pelo soro de marsupiais dos efeitos de venenos botrópicos na liberação de enzimas sarcoplasmáticas de músculos esqueléticos 1987
Estudo da interação do veneno de Bothrops e soro antibotrópico na liberação de creatinofosfoquinase de músculo esquelético 1987
A study of the interaction of Bothrops jararacussu venom and opossum sera in relation to the efflux of sarcoplasmic enzymes 1986
Effects of polyanions on the stimulation of sarcoplasmic enzyme release induced by Bothrops jararacussu venom 1985
Effects of denervation on the release of sarcoplasmic enzymes from mammalian muscles 1985
Intracerebroventricular 6-hydroxydopamine (6-OHDA) and 5,7 dihidroxytryptamine (5,7-DHT) did not change the lidocaine seizure threshold. 1984
Effect of intracisternal and intraventricular injection of serotonin, dopamine and their precursor on the seizure threshold to lidocaine 1982
Evidências do envolvimento de via serotoninérgica na gênese da convulsão pela lidocaina 1979
Efeitos da Infusão venosa de noradrenalina e CaCl2 no limiar convulsivo à lidocaina 1978
Efeitos do N2O no limiar convulsivo à lidocaina em ratos. 1978
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