Sergio Teixeira Ferreira

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa Neurobiologia/Biof

ORCID:

https://orcid.org/0000-0001-7160-9866


Formação:
  • University of Illinois at Urbana-Champaign

    | Pós-Doutorado | 1992 - 1994
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 1987 - 1989
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Mestrado | 1985 - 1987
  • Universidade Federal do Rio de Janeiro

    Química | Graduação | 1981 - 1985
Laboratórios:
Nuvens de Palavras:
Artigos:

(82.18% artigos com DOI)

Titulo DOI Ano
Brain FNDC5/irisin expression in patients and mouse models of major depression 10.1523/ENEURO.0256-22.2023. 2023
Defective proteostasis in Alzheimer?s disease 10.1016/j.arr.2023.101862 2023
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer?s disease by improving synaptic function and proteostasis 10.1016/j.ymthe.2023.03.028 2023
Oxytocin attenuates microglial activation and restores social and non-social memory in APP/PS1 Alzheimer model mice 10.1016/j.isci.2023.106545 2023
Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice 10.1002/alz.13134 2023
AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models 10.1016/j.ymthe.2022.11.002 2023
Synaptic proteasome is inhibited in Alzheimer?s disease models and associates with memory impairment in mice 10.1038/s42003-023-05511-9 2023
Association of the fibronectin type III domain-containing protein 5 rs1746661 single nucleotide polymorphism with reduced brain glucose metabolism in elderly humans 10.1093/braincomms/fcad216 2023
Impaired insulin signalling and allostatic load in Alzheimer disease 10.1038/s41583-022-00558-9 2022
Irisin stimulates protective signaling pathways in rat hippocampal neurons 10.3389/fncel.2022.953991 2022
Uncovering bidirectional brain-body interactions in health and disease 10.1016/j.neuropharm.2022.109073 2022
Biomarkers for dementia in Latin American countries: Gaps and opportunities 10.1002/alz.12757 2022
Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans 10.1038/s41398-022-02208-1 2022
Lung inflammation induced by silica particles triggers hippocampal inflammation, synapse damage and memory impairment in mice 10.1186/s12974-022-02662-0 2022
Purinergic signaling in cognitive impairment and neuropsychiatric symptoms of Alzheimer's disease 10.1016/j.neuropharm.2022.109371 2022
Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer?s disease 10.1126/scisignal.abc5429 2021
Innate immune memory mediates increased susceptibility to Alzheimer?s disease-like pathology in sepsis surviving mice 10.1016/j.bbi.2021.04.001 2021
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer?s disease 10.1038/s41398-021-01349-z 2021
Dementia is an age-independent risk factor for severity and death in COVID-19 inpatients 10.1002/alz.12352 2021
Rapid size-exclusion high performance liquid chromatography method for the quality control of amyloid-β oligomers 10.1016/j.chroma.2021.462024 2021
Brain insulin, insulin-like growth factor 1 and glucagon-like peptide 1 signalling in Alzheimer?s disease 10.1111/jne.12959 2021
Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers 10.1186/s12974-021-02099-x 2021
Cerebrospinal Fluid Neurotransmitters, Cytokines, and Chemokines in Alzheimer?s and Lewy Body Diseases 10.3233/jad-210147 2021
Dementia in Latin America: Paving the way toward a regional action plan 10.1002/alz.12202 2021
Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular, and Alzheimer?s diseases 10.1111/jnc.15129 2021
A Specialized Nutritional Formulation Prevents Hippocampal Glial Activation and Memory Impairment Induced by Amyloid-β Oligomers in Mice 10.3233/jad-210139 2021
Inflammation at the crossroads of COVID-19, cognitive deficits and depression. Neuropharmacology 10.1016/j.neuropharm.2022.109023. 2021
Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α 10.1016/j.celrep.2020.01.072 2020
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the Central Nervous System 10.1016/j.tins.2020.04.004 2020
Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice 10.1038/s41598-020-63685-2 2020
Amyloid-B oligomers in cellular models of Alzheimers disease 10.111/jcn.150.30 2020
Cerebrospinal fluid irisin correlates with amyloid-β, BDNF, and cognition in Alzheimer's disease 10.1002/dad2.12034 2020
Insulin and leptin as potential cognitive enhancers in metabolic disordes and Alzheimer's disease 10.1016/j.neuropharm.2020 2020
Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model 10.1007/s12035-019-01827-y 2020
The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer?s-linked amyloid-β oligomers in mice 10.1097/fbp.0000000000000578 2020
LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis 10.3233/jad-190742 2020
Mania-like elevated mood in rats: Enhanced 50-kHz ultrasonic vocalizations after sleep deprivation 10.1016/j.pnpbp.2018.07.002 2019
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models 10.1038/s41591-018-0275-4 2019
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice 10.1038/s41467-019-11866-7 2019
Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health 10.3389/fnins.2019.00265 2019
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice 10.1038/s41419-019-1529-x 2019
Using a portable total reflection X-ray fluorescence system for a multielement analysis of Swiss mice brains with experimental Alzheimer's disease induced by β-amyloid oligomers 10.1002/xrs.3044 2019
Extracellular vesicles derived from human Wharton?s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers 10.1186/s13287-019-1432-5 2019
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers 10.1074/jbc.m117.807180 2018
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease 10.1002/path.5056 2018
Acute and chronic neurological consequences of early-life Zika virus infection in mice 10.1126/scitranslmed.aar2749 2018
Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones? 10.1016/j.neuropharm.2018.05.021 2018
Free-floating adult human brain-derived slice cultures as a model to study the neuronal impact of Alzheimer’s disease-associated Aβ oligomers 10.1016/j.jneumeth.2018.05.021 2018
Brain Inflammation Connects Cognitive and Non-Cognitive Symptoms in Alzheimer?s Disease 10.3233/jad-179925 2018
Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression 10.3389/fpsyt.2018.00561 2018
Blood Levels of Glutamate and Glutamine in Recent Onset and Chronic Schizophrenia 10.3389/fpsyt.2018.00713 2018
Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice 10.1007/s12035-016-0307-3 2018
Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer?s and Parkinson?s Diseases 10.1007/s40263-018-0593-6 2018
Getting a ¿GRiP¿ on Hypothalamic Endoplasmic Reticulum Stress to Combat Obesity 10.2337/dbi16-0057 2017
Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer?s Therapy? 10.3389/fnagi.2017.00007 2017
Brain infusion of ?-synuclein oligomers induces motor and non-motor Parkinson?s disease-like symptoms in mice 10.1016/j.bbr.2017.06.047 2017
Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons 10.1074/jbc.m116.753525 2017
Crosstalk between endoplasmic reticulum stress and brain inflammation in Alzheimer's disease 10.1016/j.neuropharm.2017.11.016 2017
A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers 10.1111/jnc.14118 2017
Diazepam Inhibits Electrically Evoked and Tonic Dopamine Release in the Nucleus Accumbens and Reverses the Effect of Amphetamine 10.1021/acschemneuro.6b00358 2017
Multielement concentration analysis of Swiss mice brains on experimental model of Alzheimer's disease induced by β -amyloid oligomers 10.1002/xrs.2753 2017
Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice 10.1074/jbc.m116.761189 2017
Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice 10.1016/j.bbi.2017.04.007 2017
Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers 10.1091/mbc.e17-06-0416 2017
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model 10.1523/jneurosci.3351-16.2017 2017
Crosstalk between brain innate immunity and serotonin signaling underlies depressive-like behavior induced by Alzheimer's amyloid-β oligomers in mice 10.1523/JNEUROSCI.1269-16.2016 2016
Alzheimer-associated A  oligomers impact the central nervous system to induce peripheral metabolic deregulation 10.15252/emmm.201404183 2015
d-serine levels in Alzheimer’s disease: implications for novel biomarker development 10.1038/tp.2015.52 2015
Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinson’s disease 10.3389/fncel.2015.00097 2015
Neuronal stress signaling and eIF2α phosphorylation as molecular links between Alzheimer's disease and diabetes 10.1016/j.pneurobio.2015.03.003 2015
Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer⿿s disease 10.3389/fncel.2015.00191 2015
USP46: a new piece of the memory puzzle? 10.1111/jnc.13227 2015
Microglial dysfunction connects depression and Alzheimer?s disease 10.1016/j.bbi.2015.11.011 2015
How does brain insulin resistance develop in Alzheimer's disease? 10.1016/j.jalz.2013.12.004 2014
Inflammation, > defective insulin signaling and neuronal dysfunction in Alzheimer?s disease 10.1016/j.jalz.2013.12.010 2014
Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain 10.2174/1567205011666140302200902 2014
Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease 10.2337/db13-1954 2014
Alzheimer's Disease-Like Pathology Induced by Amyloid-  Oligomers in Nonhuman Primates 10.1523/jneurosci.1353-14.2014 2014
Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer?s disease. 10.1111/jnc.12304 2013
Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A  Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers 10.1523/jneurosci.0482-13.2013 2013
Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis 10.1038/cddis.2013.325 2013
The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid-  Oligomer Toxicity 10.1523/JNEUROSCI.3214-13.2013 2013
Rescue of Amyloid-Beta-Induced Inhibition of Nicotinic Acetylcholine Receptors by a Peptide Homologous to the Nicotine Binding Domain of the Alpha 7 Subtype 10.1371/journal.pone.0067194 2013
TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer?s β-Amyloid Oligomers in Mice and Monkeys 10.1016/j.cmet.2013.11.002 2013
Amyloid-  oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons 10.1091/mbc.e12-12-0858 2013
2,4-dinitrophenol induces neural differentiation of murine embryonic stem cells 10.1016/j.scr.2013.09.016 2013
 -Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid   (A )-associated Cell Death 10.1074/jbc.m111.323626 2012
Plasma levels of D-serine in Brazilian individuals with schizophrenia 10.1016/j.schres.2012.09.014 2012
Human Apolipoprotein A-I Natural Variants: Molecular Mechanisms Underlying Amyloidogenic Propensity 10.1371/journal.pone.0043755 2012
Inhibition of Choline Acetyltransferase as a Mechanism for Cholinergic Dysfunction Induced by Amyloid-  Peptide Oligomers 10.1074/jbc.m111.321448 2012
Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice 10.1038/mp.2012.168 2012
Amyloid-  Oligomers Induce Differential Gene Expression in Adult Human Brain Slices 10.1074/jbc.m111.298471 2012
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer-s disease-associated Aβ oligomers 10.1172/JCI57256 2012
Amyloid-beta decreases nitric oxide production in cultured retinal neurons: A possible mechanism for synaptic dysfunction in Alzheimer's disease? 10.1007/s11064-010-0287-z 2011
Protein kinase C activity regulates d-serine availability in the brain 10.1111/j.1471-4159.2010.07102.x 2011
Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca 10.1089/ars.2010.3287 2011
Aβ Oligomers instigate the release of excitarory amino acids from hippocampal neurons 10.2174/156720511796391917 2011
Activation of D1/D5 dopamine receptors protects neurons from synapse dysfunction induced by amyloid-beta oligomers 10.1074/jbc.M110.177790 2011
Amyloid-beta oligomers increase the localization of prion protein at the cell surface 10.1111/j.1471-4159.2011.07225.x 2011
Human apolipoprotein A-I-derived amyloid: Its association with atherosclerosis 10.1371/journal.pone.0022532 2011
Secreted Human Amyloid Precursor Protein Binds Semaphorin 3a and Prevents Semaphorin-Induced Growth Cone Collapse 10.1371/journal.pone.0022857 2011
The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. 10.1016/j.nlm.2011.08.003 2011
Nicotinic Receptors, Amyloid-β, and Synaptic Failure in Alzheimer⿿s Disease 10.1007/s12031-009-9237-0 2010
2,4-Dinitrophenol Blocks Neurodegeneration and Preserves Sciatic Nerve Function after Trauma 10.1089/neu.2009.1189 2010
Amyloid-  Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3  in Primary Cultured Hippocampal Neurons 10.1523/JNEUROSCI.1074-10.2010 2010
Expression profile of rat hippocampal neurons treated with the neuroprotective compound 2,4-dinitrophenol: up-regulation of cAMP signaling genes 10.1007/s12640-009-9133-y 2010
Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria 10.1371/journal.pone.0015230 2010
N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer?s toxic amyloid-β peptide oligomers 10.1111/j.1471-4159.2010.07058.x 2010
Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity. 10.1016/j.biocel.2008.12.003 2009
Conformational plasticity of DM43, a metalloproteinase inhibitor from Didelphis marsupialis: Chemical and pressure-induced equilibrium (un)folding studies 10.1016/j.bbapap.2009.03.010 2009
From the Cover: Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of A  oligomers 10.1073/pnas.0809158106 2009
Amyloid-  Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/ -Catenin Signaling 10.1074/jbc.m707108200 2008
Reductive inactivation of yeast glutathione reductase by Fe(II) and NADPH. 10.1016/j.cbpa.2007.03.025 2008
Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line 10.4067/S0716-97602008000200001 2008
Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts 10.1016/j.pneurobio.2007.02.001 2007
Whither Latin America? Trends and challenges of science in Latin America. 10.1080/15216540701258751 2007
Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer?s disease 10.2174/156720507781077287 2007
Soluble protein oligomers as emerging toxins in amyloid diseases 10.1080/15216540701283882 2007
Abeta oligomers induce neuronal oxidative stress through an NMDA receptor-dependent mechanism that is blocked by the Alzheimer?s drug memantine 10.1074/jbc.M607483200 2007
Soluble oligomers from a non-disease related protein mimic Aβ-induced tau hyperphosphorylation and neurodegeneration 10.1111/j.1471-4159.2007.04809.x 2007
Interrogating global gene expression in rat neuronal cultures using SAGE 10.1007/bf03033905 2007
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus. 10.1080/15216540600702198 2007
Small Molecule Inhibitors of Lysozyme Amyloid Aggregation 10.1385/cbb:44:3:549 2006
Metastable, Partially Folded States in the Productive Folding and in the Misfolding and Amyloid Aggregation of Proteins 10.1385/cbb:44:3:539 2006
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. 2006
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol:The gentle face of Janus 2006
Quantitative analysis of microscopic images 10.1016/j.cpc.2006.06.014 2006
Long-lived conformational isomerism of protein dimers: Role of the free energy of subunit association 10.1529/biophysj.106.089706 2006
Formation of Soluble Oligomers and Amyloid Fibrils with Physical Properties of the Scrapie Isoform of the Prion Protein from the C-terminal Domain of Recombinant Murine Prion Protein mPrP-(121-231) 10.1074/jbc.m605367200 2006
Acid- and pressure-induced (un)folding of yeast glutathione reductase: Competition between protein oligomerization and aggregation 10.1016/j.biocel.2005.04.007 2005
Folding and stability of a coiled-coil investigated using chemical and physical denaturing agents: Comparative analysis of polymerized and non-polymerized forms of α-tropomyosin 10.1016/j.biocel.2005.01.008 2005
Stabilization of partially folded intermediates in protein folding/misfolding transitions using hydrostatic pressure 10.1590/S0100-879X2005000800009 2005
Peptide Blockers of the Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Amyloid   10.1074/jbc.m502406200 2005
Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound 10.1096/fj.05-3812com 2005
Activation of GABAA receptors by taurine and muscimol blocks the neurotoxicity of β-amyloid in rat hippocampal and cortical neurons 10.1016/j.neuropharm.2005.06.015 2005
Heparin binding sites in granulocyte-macrophage colony-stimulating factor: Localization and regulation by histidine ionization 2005
Structural and morphological characterization of hemozoin produced by Schistosoma mansoni and Rhodnius prolixus 10.1016/j.febslet.2005.09.035 2005
Protein Folding, Misfolding and Aggregation: Evolving Concepts and Conformational Diseases 10.2174/0929866053587156 2005
Inhibition of yeast glutathione reductase by trehalose: Possible Implications in yeast survival and recovery from stress 10.1016/j.biocel.2003.10.006 2004
Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis 10.1074/jbc.M308174200 2004
Formation of amyloid fibrils from human lysozyme and its disease-associated variants using hydrostatic pressure 10.1096/fj.03-1072fje 2004
Biological evaluation of a protein isolate from cowpea (Vigna unguiculata) 10.1021/jf0340052 2004
Taurine prevents the neurotoxicity of B-amyloid and glutamate receptor agonists: Activation of GABA receptors and possible implications ofr Alzheimeris disease and other neurological disorders 10.1096/fj.03-0739com 2004
Inhibition of Heme Aggregation by Chloroquine Reduces Schistosoma mansoni Infection 10.1086/422759 2004
Amyloidogenecity and citotoxicity of recombinant mature human islet amyloid polypeptide (IAPP) 10.1074/jbc.M406108200 2004
Targeting the neurotoxic species in Alzheimer's disease: Inhibitors of AB oligomerization 10.1096/fj.04-1764com 2004
Folding and stability of the extracellular domain of the human amyloid precursor protein 10.1074/jbc.M303189200 2003
Functional properties of purified vicilins from cowpea (Vigna unguiculata) and pea (Pisum sativum) and cowpea protein isolate 2003
Neuroprotection against AB and glutamate toxicity by melatonin: are GABA receptors involved? 2003
Pré-dissociated dimers and molten globule monomers in the equilibrium unfolding of yeast glutathione reductase 2003
Closed conformation of the active site loop of rabbit muscle triophosphate isomerase in the absence of substrate: evidence of conformational heterogeneity 10.1016/j.jmb.2003.10.022 2003
Persistent conformational heterogeneity of triosephosphate isomerase: Physical and characterization of conformational isomers in solution 10.1021/bi0343572 2003
Folding intermediates of the prion protein stabilized by hydrostatic pressure and low temperature 10.1074/jbc.M307354200 2003
Folding of a de Novo Designed Native-like Four-helix Bundle Protein 10.1074/jbc.m105232200 2002
Physiopathological modulators of amyloid aggregation and novel pharmacological approaches in Alzheimer's disease 10.1590/S0001-37652002000200006 2002
Solution Studies and Structural Model of the Extracellular Domain of the Human Amyloid Precursor Protein 10.1016/s0006-3495(02)75351-4 2002
B-amyloid production, aggregation and clearence as targets or treatment in Alzheimer's disease 2002
Equilibrium unfolding and conformational plasticity of troponin I and T 10.1046/j.1432-1033.2002.03248.x 2002
Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases 2001
Iron-iduced oxidative damage of corn root plasma membrane H+ ATPase 2001
Dimethyl sulfixide promotes the K+ -independent activity of pyruvate kinase and the acquisition of the active catalitic conformation 2001
Dual role of glutamatergic neurotransmission on amyloid β1â--42 aggregation and neurotoxicity in embryonic avian retina 10.1016/s0304-3940(01)01585-3 2001
Inhibition of Alzheimer's Disease B-amyloid aggregation, neurotoxicity and in vivo deposition by nitrophenols: Implications for Alzheimer's treatment 2001
Folding Intermediates of a Model Three-helix Bundle Protein. PRESSURE AND COLD DENATURATION STUDIES 10.1074/jbc.m009622200 2001
Crystal structures of bovine β-lactoglobulin in the orthorhombic space group C2221 10.1046/j.1432-1033.2001.01918.x 2001
Selective Neoglycosylation Increases the Structural Stability of Vicilin, the 7S Storage Globulin From Pea Seeds. 2000
Pressure denaturation of beta-lactoglobulin. Different stabilities of isoforms A and B, and an investigation of the Tanford transition 10.1046/j.1432-1327.2000.01226.x 2000
Inhibition of the Ecto-ATPdiphosphohydrolase of Schistosoma mansoni by Thapsigargin 2000
Preliminary X-ray diffraction studies of rabbit muscle triose phosphate isomerase (TIM) 10.1107/s0907444900011380 2000
Haemozoin in Schistosoma mansoni 10.1016/s0166-6851(00)00299-1 2000
Subunit dissociation and inactivation of pyruvate kinase by hydrostatic pressure. Oxidation of sulfhydryl groups and ligand effects on enzyme stability 10.1046/j.1432-1327.1999.00840.x 1999
Acidic pH Modulates The Interaction Between Human Granulocyte-Macrophage Colony Stimulating Factor And Glycosaminoglycans 1999
Oxidative Damage To Sarcoplasmatic Reticulum Ca2+-ATPase At Submicromolar Iron Concentrations: Evidence For Metal-Catalysed Oxidation. 1998
Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine 10.1046/j.1432-1327.1998.2510516.x 1998
Pressure-Induced Subunit Dissociation And Unfolding Of Dimeric B-Lactoglobulin 1998
Kinetics and Energetics of Subunit Dissociation/Unfolding of TIM:  The Importance of Oligomerization for Conformational Persistence and Chemical Stability of Proteins 10.1021/bi9721593 1998
International symposium on protein condensation, in honor of Gregorio Weber 1998
Effects Of Glycosylation On Functional Properties Of Vicilin, The 7s Storage Globulin From Pea (Pisum Sativum) Seeds 1997
Role of Phospholipids in the Protein Stability of an Insect Lipoprotein, Lipophorin from 10.1021/bi9706069 1997
Intrinsic Fluorescence As A Probe Of Structure-Function Relationships In Ca-Transport ATPases 1996
Deterministic Pressure Dissociation and Unfolding of Triose Phosphate Isomerase:  Persistent Heterogeneity of a Protein Dimer 10.1021/bi952118b 1996
Oxidative Damage To Sarcoplasmatic Reticulum Ca2+-Pump Induced By Fe2+/H2O2/Ascorbate Is Not Mediated By Lipid Peroxidation Or Thiol Oxidation And Involves Protein Fragmentation 1996
Partial Purification and Immunohistochemical Localization of ATP Diphosphohydrolase from Schistosoma mansoni. IMMUNOLOGICAL CROSS-REACTIVITIES WITH POTATO APYRASE AND TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE HYDROLASE 10.1074/jbc.271.36.22139 1996
Refolding of Triosephosphate Isomerase in Low-Water Media Investigated by Fluorescence Resonance Energy Transfer 10.1021/bi961548e 1996
Effect Of Hydrostatic Pressure On The Fluorescence Of Tryptophan And Tryptophan Derivatives 1996
The Ecto-ATPases Of Endoparasites And Of Blood Cells And Vessels 1995
Deterministic Pressure-Induced Dissociation Of Vicilin, The 7s Storage Globulin From Pea Seeds: Effects Of pH And Co-Solvents On Oligomer Stability 1994
Conformational Dynamics Of Bovine Cu, Zn Superoxide Dismutase Revealed By Time-Resolved Fluorescence Spectroscopy Of The Single Tyrosine Residue. 1994
Betaine counteracts urea-induced conformational changes and uncoupling of the human erythrocyte Ca2+ pump 10.1111/j.1432-1033.1994.tb18830.x 1994
Anisotropic Rotational Diffusion Of The Adenine Moiety Of 1, N-Ethenoadenosine In Viscuos Media Investigated By Time-Resolved Fluorescence Spectroscopy 1994
Inter-Active Site Distance And Solution Dynamics Of A Bivalent-Bispecific Single-Chain Antibody Molecule 1994
Structural Flutuations In Proteins Revealed By Time-Resolved Fluorescence Spectroscopy 1993
Characterization And Localization Of An ATP-Diphosphohydrolase On The External Surface Of The Tegument Of Schistosoma Mansoni 1993
FLUORESCENCE LIFETIME AND QUENCHING STUDIES OF SARCOPLASMIC RETICULUM CA -ADENOSINE-5'-TRIPHOSPHATASE 10.1111/j.1751-1097.1993.tb09548.x 1993
Time-Resolved Fluorescence Of Erythrocyte Plasma Membrane Ca-ATPase In Different Functional States 1992
Global Analysis Of Wavelength - Resolved Fluorescence Decay In Sarcoplasmic Reticulum Calcium - ATPase 1991
Dissociation Of Purified Erythocyte Ca-ATPase By Hydrostatic Pressure 1991
Hydration And Protein Substates: Fluorescence Of Proteins In Reserve Micelles 1990
Fluorescence Decay Of Sarcoplasmic Reticulum Calcium-AtPase: Ligand Binding And Hydration Effects 1989
Fluorescence Studies On The Conformational Dynamics Of Parvalbumin In Solution: Lifetime And Rotational Montions Of The Single Tryptophan Residue 1989
Stoichiometry And Mapping Of The Nucleotide Sites In Sarcoplasmic Reticulum ATPase With The Use Of UTP 1988
Probing The ATP Binding Sites Of The Calcium-ATPase From Sarcoplasmic Reticulum By Photoaffinity Lobeling Photoaffinity Labeling. 1986
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