Sergio Teixeira Ferreira
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Programa Neurobiologia/Biof
Formação:
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University of Illinois at Urbana-Champaign
| Pós-Doutorado | 1992 - 1994
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Doutorado | 1987 - 1989
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Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Mestrado | 1985 - 1987
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Universidade Federal do Rio de Janeiro
Química | Graduação | 1981 - 1985
Laboratórios:
Nuvens de Palavras:
Artigos:
(82.18% artigos com DOI)
Titulo | DOI | Ano |
---|---|---|
Brain FNDC5/irisin expression in patients and mouse models of major depression | 10.1523/ENEURO.0256-22.2023. | 2023 |
Defective proteostasis in Alzheimer?s disease | 10.1016/j.arr.2023.101862 | 2023 |
The unfolded protein response transcription factor XBP1s ameliorates Alzheimer?s disease by improving synaptic function and proteostasis | 10.1016/j.ymthe.2023.03.028 | 2023 |
Oxytocin attenuates microglial activation and restores social and non-social memory in APP/PS1 Alzheimer model mice | 10.1016/j.isci.2023.106545 | 2023 |
Alzheimer's disease brain-derived extracellular vesicles reveal altered synapse-related proteome and induce cognitive impairment in mice | 10.1002/alz.13134 | 2023 |
AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models | 10.1016/j.ymthe.2022.11.002 | 2023 |
Synaptic proteasome is inhibited in Alzheimer?s disease models and associates with memory impairment in mice | 10.1038/s42003-023-05511-9 | 2023 |
Association of the fibronectin type III domain-containing protein 5 rs1746661 single nucleotide polymorphism with reduced brain glucose metabolism in elderly humans | 10.1093/braincomms/fcad216 | 2023 |
Impaired insulin signalling and allostatic load in Alzheimer disease | 10.1038/s41583-022-00558-9 | 2022 |
Irisin stimulates protective signaling pathways in rat hippocampal neurons | 10.3389/fncel.2022.953991 | 2022 |
Uncovering bidirectional brain-body interactions in health and disease | 10.1016/j.neuropharm.2022.109073 | 2022 |
Biomarkers for dementia in Latin American countries: Gaps and opportunities | 10.1002/alz.12757 | 2022 |
Age-linked suppression of lipoxin A4 associates with cognitive deficits in mice and humans | 10.1038/s41398-022-02208-1 | 2022 |
Lung inflammation induced by silica particles triggers hippocampal inflammation, synapse damage and memory impairment in mice | 10.1186/s12974-022-02662-0 | 2022 |
Purinergic signaling in cognitive impairment and neuropsychiatric symptoms of Alzheimer's disease | 10.1016/j.neuropharm.2022.109371 | 2022 |
Correction of eIF2-dependent defects in brain protein synthesis, synaptic plasticity, and memory in mouse models of Alzheimer?s disease | 10.1126/scisignal.abc5429 | 2021 |
Innate immune memory mediates increased susceptibility to Alzheimer?s disease-like pathology in sepsis surviving mice | 10.1016/j.bbi.2021.04.001 | 2021 |
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer?s disease | 10.1038/s41398-021-01349-z | 2021 |
Dementia is an age-independent risk factor for severity and death in COVID-19 inpatients | 10.1002/alz.12352 | 2021 |
Rapid size-exclusion high performance liquid chromatography method for the quality control of amyloid-β oligomers | 10.1016/j.chroma.2021.462024 | 2021 |
Brain insulin, insulin-like growth factor 1 and glucagon-like peptide 1 signalling in Alzheimer?s disease | 10.1111/jne.12959 | 2021 |
Interleukin-1β mediates alterations in mitochondrial fusion/fission proteins and memory impairment induced by amyloid-β oligomers | 10.1186/s12974-021-02099-x | 2021 |
Cerebrospinal Fluid Neurotransmitters, Cytokines, and Chemokines in Alzheimer?s and Lewy Body Diseases | 10.3233/jad-210147 | 2021 |
Dementia in Latin America: Paving the way toward a regional action plan | 10.1002/alz.12202 | 2021 |
Roles of glutamate receptors in a novel in vitro model of early, comorbid cerebrovascular, and Alzheimer?s diseases | 10.1111/jnc.15129 | 2021 |
A Specialized Nutritional Formulation Prevents Hippocampal Glial Activation and Memory Impairment Induced by Amyloid-β Oligomers in Mice | 10.3233/jad-210139 | 2021 |
Inflammation at the crossroads of COVID-19, cognitive deficits and depression. Neuropharmacology | 10.1016/j.neuropharm.2022.109023. | 2021 |
Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α | 10.1016/j.celrep.2020.01.072 | 2020 |
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the Central Nervous System | 10.1016/j.tins.2020.04.004 | 2020 |
Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice | 10.1038/s41598-020-63685-2 | 2020 |
Amyloid-B oligomers in cellular models of Alzheimers disease | 10.111/jcn.150.30 | 2020 |
Cerebrospinal fluid irisin correlates with amyloid-β, BDNF, and cognition in Alzheimer's disease | 10.1002/dad2.12034 | 2020 |
Insulin and leptin as potential cognitive enhancers in metabolic disordes and Alzheimer's disease | 10.1016/j.neuropharm.2020 | 2020 |
Adenovirus-Mediated Transduction of Insulin-Like Growth Factor 1 Protects Hippocampal Neurons from the Toxicity of Aβ Oligomers and Prevents Memory Loss in an Alzheimer Mouse Model | 10.1007/s12035-019-01827-y | 2020 |
The aroylhydrazone INHHQ prevents memory impairment induced by Alzheimer?s-linked amyloid-β oligomers in mice | 10.1097/fbp.0000000000000578 | 2020 |
LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis | 10.3233/jad-190742 | 2020 |
Mania-like elevated mood in rats: Enhanced 50-kHz ultrasonic vocalizations after sleep deprivation | 10.1016/j.pnpbp.2018.07.002 | 2019 |
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimers models | 10.1038/s41591-018-0275-4 | 2019 |
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice | 10.1038/s41467-019-11866-7 | 2019 |
Diet-Derived Fatty Acids, Brain Inflammation, and Mental Health | 10.3389/fnins.2019.00265 | 2019 |
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice | 10.1038/s41419-019-1529-x | 2019 |
Using a portable total reflection X-ray fluorescence system for a multielement analysis of Swiss mice brains with experimental Alzheimer's disease induced by β-amyloid oligomers | 10.1002/xrs.3044 | 2019 |
Extracellular vesicles derived from human Wharton?s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers | 10.1186/s13287-019-1432-5 | 2019 |
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers | 10.1074/jbc.m117.807180 | 2018 |
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease | 10.1002/path.5056 | 2018 |
Acute and chronic neurological consequences of early-life Zika virus infection in mice | 10.1126/scitranslmed.aar2749 | 2018 |
Are Alzheimer's disease and other neurodegenerative disorders caused by impaired signalling of insulin and other hormones? | 10.1016/j.neuropharm.2018.05.021 | 2018 |
Free-floating adult human brain-derived slice cultures as a model to study the neuronal impact of Alzheimers disease-associated Aβ oligomers | 10.1016/j.jneumeth.2018.05.021 | 2018 |
Brain Inflammation Connects Cognitive and Non-Cognitive Symptoms in Alzheimer?s Disease | 10.3233/jad-179925 | 2018 |
Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression | 10.3389/fpsyt.2018.00561 | 2018 |
Blood Levels of Glutamate and Glutamine in Recent Onset and Chronic Schizophrenia | 10.3389/fpsyt.2018.00713 | 2018 |
Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice | 10.1007/s12035-016-0307-3 | 2018 |
Neuroprotective Actions of Glucagon-Like Peptide-1 (GLP-1) Analogues in Alzheimer?s and Parkinson?s Diseases | 10.1007/s40263-018-0593-6 | 2018 |
Getting a ¿GRiP¿ on Hypothalamic Endoplasmic Reticulum Stress to Combat Obesity | 10.2337/dbi16-0057 | 2017 |
Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer?s Therapy? | 10.3389/fnagi.2017.00007 | 2017 |
Brain infusion of ?-synuclein oligomers induces motor and non-motor Parkinson?s disease-like symptoms in mice | 10.1016/j.bbr.2017.06.047 | 2017 |
Amyloid-β oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons | 10.1074/jbc.m116.753525 | 2017 |
Crosstalk between endoplasmic reticulum stress and brain inflammation in Alzheimer's disease | 10.1016/j.neuropharm.2017.11.016 | 2017 |
A human scFv antibody that targets and neutralizes high molecular weight pathogenic amyloid-β oligomers | 10.1111/jnc.14118 | 2017 |
Diazepam Inhibits Electrically Evoked and Tonic Dopamine Release in the Nucleus Accumbens and Reverses the Effect of Amphetamine | 10.1021/acschemneuro.6b00358 | 2017 |
Multielement concentration analysis of Swiss mice brains on experimental model of Alzheimer's disease induced by β -amyloid oligomers | 10.1002/xrs.2753 | 2017 |
Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice | 10.1074/jbc.m116.761189 | 2017 |
Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice | 10.1016/j.bbi.2017.04.007 | 2017 |
Neuroprotective astrocyte-derived insulin/insulin-like growth factor 1 stimulates endocytic processing and extracellular release of neuron-bound Aβ oligomers | 10.1091/mbc.e17-06-0416 | 2017 |
Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model | 10.1523/jneurosci.3351-16.2017 | 2017 |
Crosstalk between brain innate immunity and serotonin signaling underlies depressive-like behavior induced by Alzheimer's amyloid-β oligomers in mice | 10.1523/JNEUROSCI.1269-16.2016 | 2016 |
Alzheimer-associated A oligomers impact the central nervous system to induce peripheral metabolic deregulation | 10.15252/emmm.201404183 | 2015 |
d-serine levels in Alzheimers disease: implications for novel biomarker development | 10.1038/tp.2015.52 | 2015 |
Mitomycin-treated undifferentiated embryonic stem cells as a safe and effective therapeutic strategy in a mouse model of Parkinsons disease | 10.3389/fncel.2015.00097 | 2015 |
Neuronal stress signaling and eIF2α phosphorylation as molecular links between Alzheimer's disease and diabetes | 10.1016/j.pneurobio.2015.03.003 | 2015 |
Soluble amyloid-β oligomers as synaptotoxins leading to cognitive impairment in Alzheimer⿿s disease | 10.3389/fncel.2015.00191 | 2015 |
USP46: a new piece of the memory puzzle? | 10.1111/jnc.13227 | 2015 |
Microglial dysfunction connects depression and Alzheimer?s disease | 10.1016/j.bbi.2015.11.011 | 2015 |
How does brain insulin resistance develop in Alzheimer's disease? | 10.1016/j.jalz.2013.12.004 | 2014 |
Inflammation, > defective insulin signaling and neuronal dysfunction in Alzheimer?s disease | 10.1016/j.jalz.2013.12.010 | 2014 |
Accumulation of Intraneuronal Amyloid-β is Common in Normal Brain | 10.2174/1567205011666140302200902 | 2014 |
Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease | 10.2337/db13-1954 | 2014 |
Alzheimer's Disease-Like Pathology Induced by Amyloid- Oligomers in Nonhuman Primates | 10.1523/jneurosci.1353-14.2014 | 2014 |
Deregulation of excitatory neurotransmission underlying synapse failure in Alzheimer?s disease. | 10.1111/jnc.12304 | 2013 |
Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers | 10.1523/jneurosci.0482-13.2013 | 2013 |
Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis | 10.1038/cddis.2013.325 | 2013 |
The Prion Protein Ligand, Stress-Inducible Phosphoprotein 1, Regulates Amyloid- Oligomer Toxicity | 10.1523/JNEUROSCI.3214-13.2013 | 2013 |
Rescue of Amyloid-Beta-Induced Inhibition of Nicotinic Acetylcholine Receptors by a Peptide Homologous to the Nicotine Binding Domain of the Alpha 7 Subtype | 10.1371/journal.pone.0067194 | 2013 |
TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer?s β-Amyloid Oligomers in Mice and Monkeys | 10.1016/j.cmet.2013.11.002 | 2013 |
Amyloid- oligomers induce tau-independent disruption of BDNF axonal transport via calcineurin activation in cultured hippocampal neurons | 10.1091/mbc.e12-12-0858 | 2013 |
2,4-dinitrophenol induces neural differentiation of murine embryonic stem cells | 10.1016/j.scr.2013.09.016 | 2013 |
-Secretase-derived Fragment of Cellular Prion, N1, Protects against Monomeric and Oligomeric Amyloid (A )-associated Cell Death | 10.1074/jbc.m111.323626 | 2012 |
Plasma levels of D-serine in Brazilian individuals with schizophrenia | 10.1016/j.schres.2012.09.014 | 2012 |
Human Apolipoprotein A-I Natural Variants: Molecular Mechanisms Underlying Amyloidogenic Propensity | 10.1371/journal.pone.0043755 | 2012 |
Inhibition of Choline Acetyltransferase as a Mechanism for Cholinergic Dysfunction Induced by Amyloid- Peptide Oligomers | 10.1074/jbc.m111.321448 | 2012 |
Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice | 10.1038/mp.2012.168 | 2012 |
Amyloid- Oligomers Induce Differential Gene Expression in Adult Human Brain Slices | 10.1074/jbc.m111.298471 | 2012 |
An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer-s disease-associated Aβ oligomers | 10.1172/JCI57256 | 2012 |
Amyloid-beta decreases nitric oxide production in cultured retinal neurons: A possible mechanism for synaptic dysfunction in Alzheimer's disease? | 10.1007/s11064-010-0287-z | 2011 |
Protein kinase C activity regulates d-serine availability in the brain | 10.1111/j.1471-4159.2010.07102.x | 2011 |
Amyloid β-Peptide Oligomers Stimulate RyR-Mediated Ca | 10.1089/ars.2010.3287 | 2011 |
Aβ Oligomers instigate the release of excitarory amino acids from hippocampal neurons | 10.2174/156720511796391917 | 2011 |
Activation of D1/D5 dopamine receptors protects neurons from synapse dysfunction induced by amyloid-beta oligomers | 10.1074/jbc.M110.177790 | 2011 |
Amyloid-beta oligomers increase the localization of prion protein at the cell surface | 10.1111/j.1471-4159.2011.07225.x | 2011 |
Human apolipoprotein A-I-derived amyloid: Its association with atherosclerosis | 10.1371/journal.pone.0022532 | 2011 |
Secreted Human Amyloid Precursor Protein Binds Semaphorin 3a and Prevents Semaphorin-Induced Growth Cone Collapse | 10.1371/journal.pone.0022857 | 2011 |
The Aβ oligomer hypothesis for synapse failure and memory loss in Alzheimer's disease. | 10.1016/j.nlm.2011.08.003 | 2011 |
Nicotinic Receptors, Amyloid-β, and Synaptic Failure in Alzheimer⿿s Disease | 10.1007/s12031-009-9237-0 | 2010 |
2,4-Dinitrophenol Blocks Neurodegeneration and Preserves Sciatic Nerve Function after Trauma | 10.1089/neu.2009.1189 | 2010 |
Amyloid- Peptide Oligomers Disrupt Axonal Transport through an NMDA Receptor-Dependent Mechanism That Is Mediated by Glycogen Synthase Kinase 3 in Primary Cultured Hippocampal Neurons | 10.1523/JNEUROSCI.1074-10.2010 | 2010 |
Expression profile of rat hippocampal neurons treated with the neuroprotective compound 2,4-dinitrophenol: up-regulation of cAMP signaling genes | 10.1007/s12640-009-9133-y | 2010 |
Amyloid-β triggers the release of neuronal hexokinase 1 from mitochondria | 10.1371/journal.pone.0015230 | 2010 |
N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer?s toxic amyloid-β peptide oligomers | 10.1111/j.1471-4159.2010.07058.x | 2010 |
Human apolipoprotein A-I binds amyloid-beta and prevents Abeta-induced neurotoxicity. | 10.1016/j.biocel.2008.12.003 | 2009 |
Conformational plasticity of DM43, a metalloproteinase inhibitor from Didelphis marsupialis: Chemical and pressure-induced equilibrium (un)folding studies | 10.1016/j.bbapap.2009.03.010 | 2009 |
From the Cover: Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of A oligomers | 10.1073/pnas.0809158106 | 2009 |
Amyloid-Â Binds to the Extracellular Cysteine-rich Domain of Frizzled and Inhibits Wnt/Â -Catenin Signaling | 10.1074/jbc.m707108200 | 2008 |
Reductive inactivation of yeast glutathione reductase by Fe(II) and NADPH. | 10.1016/j.cbpa.2007.03.025 | 2008 |
Small-molecule aggregation inhibitors reduce excess amyloid in a trisomy 16 mouse cortical cell line | 10.4067/S0716-97602008000200001 | 2008 |
Structure and functions of the human amyloid precursor protein: The whole is more than the sum of its parts | 10.1016/j.pneurobio.2007.02.001 | 2007 |
Whither Latin America? Trends and challenges of science in Latin America. | 10.1080/15216540701258751 | 2007 |
Cyclic AMP enhancers and Abeta oligomerization blockers as potential therapeutic agents in Alzheimer?s disease | 10.2174/156720507781077287 | 2007 |
Soluble protein oligomers as emerging toxins in amyloid diseases | 10.1080/15216540701283882 | 2007 |
Abeta oligomers induce neuronal oxidative stress through an NMDA receptor-dependent mechanism that is blocked by the Alzheimer?s drug memantine | 10.1074/jbc.M607483200 | 2007 |
Soluble oligomers from a non-disease related protein mimic Aβ-induced tau hyperphosphorylation and neurodegeneration | 10.1111/j.1471-4159.2007.04809.x | 2007 |
Interrogating global gene expression in rat neuronal cultures using SAGE | 10.1007/bf03033905 | 2007 |
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: the gentle face of Janus. | 10.1080/15216540600702198 | 2007 |
Small Molecule Inhibitors of Lysozyme Amyloid Aggregation | 10.1385/cbb:44:3:549 | 2006 |
Metastable, Partially Folded States in the Productive Folding and in the Misfolding and Amyloid Aggregation of Proteins | 10.1385/cbb:44:3:539 | 2006 |
Solution conformation and heparin-induced dimerization of the full-length extracellular domain of the human amyloid precursor protein. | 2006 | |
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol:The gentle face of Janus | 2006 | |
Quantitative analysis of microscopic images | 10.1016/j.cpc.2006.06.014 | 2006 |
Long-lived conformational isomerism of protein dimers: Role of the free energy of subunit association | 10.1529/biophysj.106.089706 | 2006 |
Formation of Soluble Oligomers and Amyloid Fibrils with Physical Properties of the Scrapie Isoform of the Prion Protein from the C-terminal Domain of Recombinant Murine Prion Protein mPrP-(121-231) | 10.1074/jbc.m605367200 | 2006 |
Acid- and pressure-induced (un)folding of yeast glutathione reductase: Competition between protein oligomerization and aggregation | 10.1016/j.biocel.2005.04.007 | 2005 |
Folding and stability of a coiled-coil investigated using chemical and physical denaturing agents: Comparative analysis of polymerized and non-polymerized forms of α-tropomyosin | 10.1016/j.biocel.2005.01.008 | 2005 |
Stabilization of partially folded intermediates in protein folding/misfolding transitions using hydrostatic pressure | 10.1590/S0100-879X2005000800009 | 2005 |
Peptide Blockers of the Inhibition of Neuronal Nicotinic Acetylcholine Receptors by Amyloid  | 10.1074/jbc.m502406200 | 2005 |
Neuritogenesis and neuronal differentiation promoted by 2,4-dinitrophenol, a novel anti-amyloidogenic compound | 10.1096/fj.05-3812com | 2005 |
Activation of GABAA receptors by taurine and muscimol blocks the neurotoxicity of β-amyloid in rat hippocampal and cortical neurons | 10.1016/j.neuropharm.2005.06.015 | 2005 |
Heparin binding sites in granulocyte-macrophage colony-stimulating factor: Localization and regulation by histidine ionization | 2005 | |
Structural and morphological characterization of hemozoin produced by Schistosoma mansoni and Rhodnius prolixus | 10.1016/j.febslet.2005.09.035 | 2005 |
Protein Folding, Misfolding and Aggregation: Evolving Concepts and Conformational Diseases | 10.2174/0929866053587156 | 2005 |
Inhibition of yeast glutathione reductase by trehalose: Possible Implications in yeast survival and recovery from stress | 10.1016/j.biocel.2003.10.006 | 2004 |
Redesigning the folding energetics of a model three-helix bundle protein by site-directed mutagenesis | 10.1074/jbc.M308174200 | 2004 |
Formation of amyloid fibrils from human lysozyme and its disease-associated variants using hydrostatic pressure | 10.1096/fj.03-1072fje | 2004 |
Biological evaluation of a protein isolate from cowpea (Vigna unguiculata) | 10.1021/jf0340052 | 2004 |
Taurine prevents the neurotoxicity of B-amyloid and glutamate receptor agonists: Activation of GABA receptors and possible implications ofr Alzheimeris disease and other neurological disorders | 10.1096/fj.03-0739com | 2004 |
Inhibition of Heme Aggregation by Chloroquine Reduces Schistosoma mansoni Infection | 10.1086/422759 | 2004 |
Amyloidogenecity and citotoxicity of recombinant mature human islet amyloid polypeptide (IAPP) | 10.1074/jbc.M406108200 | 2004 |
Targeting the neurotoxic species in Alzheimer's disease: Inhibitors of AB oligomerization | 10.1096/fj.04-1764com | 2004 |
Folding and stability of the extracellular domain of the human amyloid precursor protein | 10.1074/jbc.M303189200 | 2003 |
Functional properties of purified vicilins from cowpea (Vigna unguiculata) and pea (Pisum sativum) and cowpea protein isolate | 2003 | |
Neuroprotection against AB and glutamate toxicity by melatonin: are GABA receptors involved? | 2003 | |
Pré-dissociated dimers and molten globule monomers in the equilibrium unfolding of yeast glutathione reductase | 2003 | |
Closed conformation of the active site loop of rabbit muscle triophosphate isomerase in the absence of substrate: evidence of conformational heterogeneity | 10.1016/j.jmb.2003.10.022 | 2003 |
Persistent conformational heterogeneity of triosephosphate isomerase: Physical and characterization of conformational isomers in solution | 10.1021/bi0343572 | 2003 |
Folding intermediates of the prion protein stabilized by hydrostatic pressure and low temperature | 10.1074/jbc.M307354200 | 2003 |
Folding of a de Novo Designed Native-like Four-helix Bundle Protein | 10.1074/jbc.m105232200 | 2002 |
Physiopathological modulators of amyloid aggregation and novel pharmacological approaches in Alzheimer's disease | 10.1590/S0001-37652002000200006 | 2002 |
Solution Studies and Structural Model of the Extracellular Domain of the Human Amyloid Precursor Protein | 10.1016/s0006-3495(02)75351-4 | 2002 |
B-amyloid production, aggregation and clearence as targets or treatment in Alzheimer's disease | 2002 | |
Equilibrium unfolding and conformational plasticity of troponin I and T | 10.1046/j.1432-1033.2002.03248.x | 2002 |
Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases | 2001 | |
Iron-iduced oxidative damage of corn root plasma membrane H+ ATPase | 2001 | |
Dimethyl sulfixide promotes the K+ -independent activity of pyruvate kinase and the acquisition of the active catalitic conformation | 2001 | |
Dual role of glutamatergic neurotransmission on amyloid β1â--42 aggregation and neurotoxicity in embryonic avian retina | 10.1016/s0304-3940(01)01585-3 | 2001 |
Inhibition of Alzheimer's Disease B-amyloid aggregation, neurotoxicity and in vivo deposition by nitrophenols: Implications for Alzheimer's treatment | 2001 | |
Folding Intermediates of a Model Three-helix Bundle Protein. PRESSURE AND COLD DENATURATION STUDIES | 10.1074/jbc.m009622200 | 2001 |
Crystal structures of bovine β-lactoglobulin in the orthorhombic space group C2221 | 10.1046/j.1432-1033.2001.01918.x | 2001 |
Selective Neoglycosylation Increases the Structural Stability of Vicilin, the 7S Storage Globulin From Pea Seeds. | 2000 | |
Pressure denaturation of beta-lactoglobulin. Different stabilities of isoforms A and B, and an investigation of the Tanford transition | 10.1046/j.1432-1327.2000.01226.x | 2000 |
Inhibition of the Ecto-ATPdiphosphohydrolase of Schistosoma mansoni by Thapsigargin | 2000 | |
Preliminary X-ray diffraction studies of rabbit muscle triose phosphate isomerase (TIM) | 10.1107/s0907444900011380 | 2000 |
Haemozoin in Schistosoma mansoni | 10.1016/s0166-6851(00)00299-1 | 2000 |
Subunit dissociation and inactivation of pyruvate kinase by hydrostatic pressure. Oxidation of sulfhydryl groups and ligand effects on enzyme stability | 10.1046/j.1432-1327.1999.00840.x | 1999 |
Acidic pH Modulates The Interaction Between Human Granulocyte-Macrophage Colony Stimulating Factor And Glycosaminoglycans | 1999 | |
Oxidative Damage To Sarcoplasmatic Reticulum Ca2+-ATPase At Submicromolar Iron Concentrations: Evidence For Metal-Catalysed Oxidation. | 1998 | |
Divalent cation dependence and inhibition of Schistosoma mansoni ATP diphosphohydrolase by fluorosulfonylbenzoyl adenosine | 10.1046/j.1432-1327.1998.2510516.x | 1998 |
Pressure-Induced Subunit Dissociation And Unfolding Of Dimeric B-Lactoglobulin | 1998 | |
Kinetics and Energetics of Subunit Dissociation/Unfolding of TIM: The Importance of Oligomerization for Conformational Persistence and Chemical Stability of Proteins | 10.1021/bi9721593 | 1998 |
International symposium on protein condensation, in honor of Gregorio Weber | 1998 | |
Effects Of Glycosylation On Functional Properties Of Vicilin, The 7s Storage Globulin From Pea (Pisum Sativum) Seeds | 1997 | |
Role of Phospholipids in the Protein Stability of an Insect Lipoprotein, Lipophorin from | 10.1021/bi9706069 | 1997 |
Intrinsic Fluorescence As A Probe Of Structure-Function Relationships In Ca-Transport ATPases | 1996 | |
Deterministic Pressure Dissociation and Unfolding of Triose Phosphate Isomerase: Persistent Heterogeneity of a Protein Dimer | 10.1021/bi952118b | 1996 |
Oxidative Damage To Sarcoplasmatic Reticulum Ca2+-Pump Induced By Fe2+/H2O2/Ascorbate Is Not Mediated By Lipid Peroxidation Or Thiol Oxidation And Involves Protein Fragmentation | 1996 | |
Partial Purification and Immunohistochemical Localization of ATP Diphosphohydrolase from Schistosoma mansoni. IMMUNOLOGICAL CROSS-REACTIVITIES WITH POTATO APYRASE AND TOXOPLASMA GONDII NUCLEOSIDE TRIPHOSPHATE HYDROLASE | 10.1074/jbc.271.36.22139 | 1996 |
Refolding of Triosephosphate Isomerase in Low-Water Media Investigated by Fluorescence Resonance Energy Transfer | 10.1021/bi961548e | 1996 |
Effect Of Hydrostatic Pressure On The Fluorescence Of Tryptophan And Tryptophan Derivatives | 1996 | |
The Ecto-ATPases Of Endoparasites And Of Blood Cells And Vessels | 1995 | |
Deterministic Pressure-Induced Dissociation Of Vicilin, The 7s Storage Globulin From Pea Seeds: Effects Of pH And Co-Solvents On Oligomer Stability | 1994 | |
Conformational Dynamics Of Bovine Cu, Zn Superoxide Dismutase Revealed By Time-Resolved Fluorescence Spectroscopy Of The Single Tyrosine Residue. | 1994 | |
Betaine counteracts urea-induced conformational changes and uncoupling of the human erythrocyte Ca2+ pump | 10.1111/j.1432-1033.1994.tb18830.x | 1994 |
Anisotropic Rotational Diffusion Of The Adenine Moiety Of 1, N-Ethenoadenosine In Viscuos Media Investigated By Time-Resolved Fluorescence Spectroscopy | 1994 | |
Inter-Active Site Distance And Solution Dynamics Of A Bivalent-Bispecific Single-Chain Antibody Molecule | 1994 | |
Structural Flutuations In Proteins Revealed By Time-Resolved Fluorescence Spectroscopy | 1993 | |
Characterization And Localization Of An ATP-Diphosphohydrolase On The External Surface Of The Tegument Of Schistosoma Mansoni | 1993 | |
FLUORESCENCE LIFETIME AND QUENCHING STUDIES OF SARCOPLASMIC RETICULUM CA -ADENOSINE-5'-TRIPHOSPHATASE | 10.1111/j.1751-1097.1993.tb09548.x | 1993 |
Time-Resolved Fluorescence Of Erythrocyte Plasma Membrane Ca-ATPase In Different Functional States | 1992 | |
Global Analysis Of Wavelength - Resolved Fluorescence Decay In Sarcoplasmic Reticulum Calcium - ATPase | 1991 | |
Dissociation Of Purified Erythocyte Ca-ATPase By Hydrostatic Pressure | 1991 | |
Hydration And Protein Substates: Fluorescence Of Proteins In Reserve Micelles | 1990 | |
Fluorescence Decay Of Sarcoplasmic Reticulum Calcium-AtPase: Ligand Binding And Hydration Effects | 1989 | |
Fluorescence Studies On The Conformational Dynamics Of Parvalbumin In Solution: Lifetime And Rotational Montions Of The Single Tryptophan Residue | 1989 | |
Stoichiometry And Mapping Of The Nucleotide Sites In Sarcoplasmic Reticulum ATPase With The Use Of UTP | 1988 | |
Probing The ATP Binding Sites Of The Calcium-ATPase From Sarcoplasmic Reticulum By Photoaffinity Lobeling Photoaffinity Labeling. | 1986 |
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