Herbert Leonel de Matos Guedes

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Campus de Xerém

Unidade:

Setor de Pessoal/Xerém

Departamento:

Docentes/Xerém

ORCID:

https://orcid.org/0000-0002-3819-3069


Formação:
  • University of Texas Medical Branch at Galveston

    | Pós-Doutorado | 2013 - 2014
  • INSTITUTO DE BIOFÍSICA CARLOS CHAGAS FILHO - UFRJ

    | Pós-Doutorado | 2009 - 2011
  • INSTITUTO DE BIOFÍSICA CARLOS CHAGAS FILHO - UFRJ

    Ciências Biológicas - Biofísica (imunobiologia) | Doutorado | 2005 - 2009
  • INSTITUTO DE BIOFÍSICA CARLOS CHAGAS FILHO - UFRJ

    Ciências Biológicas - Biofísica (imunobiologia) | Mestrado | 2003 - 2005
  • Universidade Federal do Rio de Janeiro

    Farmácia | Graduação | 2000 - 2003
  • Escola Técica Federal de Química

    | Ensino Médio (2o grau) | 1994 - 1999
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:
Nenhum artigo cadastrado
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Failure in the increase of protection by association of LaAg with adjuvants by intranasal route against Leishmania amazonensis 2016
Mice under deficient diet in Vitamin D promotes increase of the resistance to L. amazonensis infection through increase of the TCD4+ IFN-gamma+ cells 2016
Evaluation of Oligopeptidase B2 overexpression in Leishmania major 2016
ROLE OF PD-1/PD-L1 IN THE INDUCTION OF REGULATORY T CELLS DURING LEISHMANIA AMAZONENSIS INFECTION 2015
Evaluation of XID mice infection by Leishmania amazonensis 2015
The role of TLR9 in the infection by Leishmania amazonensis 2015
The use of mesenchymal stem cells from adipose tissue and bone marrow as an alternative therapy to murine cutaneous leishmaniasis caused by Leishmania amazonensis in C57BL/6 2015
Martins, AMFM; PRATTI, J. E. ; Carneiro, MP ; GUEDES, H. L. M. . Optimization of Oligopeptidase B2 Vaccine against murine Leishmaniais 2014
Deficient diets on Vitamins B6 or B9 or D induced an increase resistance against Leishmania amazonensis infection in Balb/c 2013
Intranasal immunization with KMP11 associated to MPLA induced protection against Leishmania amazonensis. 2013
Association of LaAg plus AddaVax? (squelene-oil-water) failed to improve vaccine efficacy against Leishmania amazonensis infection 2013
LaAg plus saponin induced protection on Balb/c, but not on C57bl/6 2013
Vitamin D as adjuvant for nasal and oral vaccines agaisnt Leishmania amazonensis 2013
The role of TLR 9 on L. amazonensis infection and in LaAg intranasal vaccine against murine leishmaniasis on C57BL6 background. 2012
Vitamin D deficient mice increase resistance to L. amazonensis infection 2012
Immugenicity and efficacy of Leishmania amazonensis extracellular serine protease fraction (LaSP-Ex) and Oligopeptidase B2 as antileishmanial vaccines 2010
Improved Intranasal vaccine Efficacy of LACK-DNA and LaAg Leishmanial Antigens by Encapsulation in Chitosan microparticle and combined delivery 2010
Efficacy of Intranasal vaccination with LACK-DNA agaisnt Visceral Leishmaniasis in e´xperimental hamster model 2010
Evaluating the effectiveness of trasngenic tobbaco expressing the parasite antigens LACK in oral vaccination agaisnt cutaneous Leishmaniasis in mice 2010
Leishmania oligopeptidase B2 2009
Vaccination by nasal route with extracelluler serine peptidases fraction of Leishmania amazonensis induced protection against Leishmania amazonensis protection against murine leishmaniasis 2009
Produção de anticorpos anti-oligopeptidase B2 de Leishmania amazonensis 2009
Identificação e Localização Celular da Oligopeptidase B2 da Leishmania Amazonensis 2009
Clonagem e expressão heteróloga do domínio C-terminal da Oligopeptidase B2 de Leishmania amazonensis 2009
Structural Characterization of a 18 kDa Serine Protease from B. jararacussu Venom 2008
Molecular cloning, gene expression analysis and molecular model of a new oligopeptidase B from L amazonensis 2008
Molecular Modeling of Leishmania amazonensis Oligopeptidase B 2008
OPPOSING EFFECTIVENESS OF PARENTERAL VS. INTRANASAL VACCINATION WITH SOLUBLE AND EXTRACELLULAR SERINE PROTEASE FRACTIONS OF LEISHMANIA AMAZONENSIS 2007
Oligopeptidase B-Like of Leishmania amazonensis 2007
Molecular cloning, characterization and expression analysis of Oligopeptidase B of Leishmania major and Leishmania amazonensis. 2006
Purification and partial characterization of an extracellular serine oligopeptidase from Leishmania braziliensis 2006
Characterization of extracellular proteases from Leishmania amazonensis and Leishmania chagasi 2006
Structural characterization and low-resolution model of BJ-48, a thrombin-like enzyme from Bothrops jararacussu venom: Evidence of pH effect on hydrodynamic properties. 2006
Soluble Serine Proteases From L. amazonensis as Disease-promoting Components of the Intramuscular LaAg Vaccine. 2006
Efficacy of Parenteral Vaccination with the Aqueous Extract of Leishmania Amazonensis Promastigotes in the Prevention of Cutaneous Leishmaniosis 2006
Determination of a Molecular Model for BJ48 by SAXS and detection of structural modication/ 2005
Small angle X-ray scattering (SAXS) study of the giroxin toxin isolated from Lachesis muta rhombeata venom (LMR-47) 2005
THE DISEASE-PROMOTING EFFECT OF PARENTERAL VACCINATION OF MICE WITH LEISHMANIA AMAZONENSIS ANTIGENS IS DUE TO INCREASED TGF-?Ò PRODUCTION 2005
Purification, Specificity and Three-dimensional Structure Model of the Giroxin (LMR-47) Isolated from Lachesis muta rhombeata venom. 2005
Proteolytic activity of cultured Leishmania sp extracellular products 2005
Identification of extracellular serine proteases from Leishmania braziliensis. 2005
IMMUNOLOGICAL EVALUATION OF ATTENUATED LEISHMANIA AMAZONENSIS ANTIGENS 2005
EFFICACY OF PARENTERAL VACCINATION WITH DIFFERENT SERINE PROTEASES FRACTIONS OF LEISHMANIA AMAZONESIS 2005
Identification and Partial characterization of a soluble Serine Protease from Leishmania (Viannia) brasiliensis 2004
Purificação Parcial de uma Serino Protease do extrato intracelular solúvel em detergente de Leishmania (V.) braziliensis 2004
Leishmania amazonens and Leishmaia braziliensis Display Differencial capacity to induce T Cell Anergy is associated with soluble molecules 2004
Investigation of pH effect of BJ 48 by SAXS 2004
Proteses of Tambacú 2004
Identificatios of Proteases from Tambacú 2004
Structural characterization of BJ48 by SAXS 2004
Small angle X-ray scattering (SAXS) study of the giroxin toxin isolated from Lachesis muta rhombeata venom (LMR-47) 2004
Structural Characterization of M Antigen of Histoplasma capsulatum 2003
SERINO-PEPTIDASE EXTRACELULAR DE T.Cruzi 2003
PCR Diagnóstico para Identificação de Histoplasma capsulatum 2002
Identification of specific B-cell epitope from HSP-60 to improve the differencial diagnosis of Paracoccidioidomycosis, Histoplasmosis and coccidioidomycosis 2002
Genarization and enzymatic activity from fibronectin by acidic proteinase from Leishmania amazonensis 2000
Effect of synthetic peptides Cecropin/Millitin on Leishmania amazonensis Promastigote Cells 1999
A Lei de Cultivares e Proteção dos Obtentores de Novas Variedades Vegetais 1999
Impactos Trazidos pela Nova Lei de Patentes para a produção de Fármacos no Brasil 1999
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