Andrea Cheble de Oliveira

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Biologia Estrutural

ORCID:

https://orcid.org/0000-0001-9268-1058


Formação:

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 1999 - 2000

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 1994 - 1998

  • Universidade Federal do Rio de Janeiro

    Ciencias Biologicas | Graduação | 1990 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:

(72.50% artigos com DOI)

Titulo DOI Ano
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum 10.3389/fimmu.2022.884760 2022
Intradermal Immunization of SARS-CoV-2 Original Strain Trimeric Spike Protein Associated to CpG and AddaS03 Adjuvants, but Not MPL, Provide Strong Humoral and Cellular Response in Mice 10.3390/vaccines10081305 2022
COVID-19 and the challenges of chemotherapy: The failure case of hydroxychloroquine in the clinical treatment of SARS-CoV-2 infection 10.2174/2666796702999210112202907 2021
Inactivation of avian influenza viruses by hydrostatic pressure as potential vaccine development approach 10.1099/acmi.0.000220 2021
Yellow Fever Vaccine Protects Mice Against Zika Virus Infection 10.1371/journal.pntd.0009907 2021
Influence of iron binding in the structural stability and cellular internalization of bovine lactoferrin 10.1016/j.heliyon.2021.e08087 2021
Polyclonal F(ab’)2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency 10.1016/j.isci.2021.103315 2021
Soro convalescente contra a covid-19 2020
Agathisflavone, a biflavonoid from Anacardium occidentale L., inhibits influenza virus' neuraminidase 10.2174/1568026620666191219150738 2019
Stability of different influenza subtypes: How can high hydrostatic pressure be a useful tool for vaccine development? 10.1016/j.bpc.2017.04.002 2017
On the entry of an emerging arbovirus into host cells: Mayaro virus takes the highway to the cytoplasm through fusion with early endosomes and caveolae-derived vesicles 10.7717/peerj.3245 2017
Fusion of a New World Alphavirus with Membrane Microdomains Involving Partially Reversible Conformational Changes in the Viral Spike Proteins 10.1021/acs.biochem.7b00650 2017
Impairing the function of MLCK, myosin Va or myosin Vb disrupts Rhinovirus B14 replication 10.1038/s41598-017-17501-z 2017
A biophysical characterization of the interaction of a hepatitis C virus membranotropic peptide with micelles 10.1016/j.bbapap.2016.01.003 2016
Charge neutralization as the major factor for the assembly of nucleocapsid-like particles from C-terminal truncated hepatitis C virus core protein 10.7717/peerj.2670 2016
Intranasal Immunization with Pressure Inactivated Avian Influenza Elicits Cellular and Humoral Responses in Mice 10.1371/journal.pone.0128785 2015
High Pressure Chemical Biology and Biotechnology 2014
Inhibition of Mayaro virus infection by bovine lactoferrin 10.1016/j.virol.2014.01.022 2014
Full Inactivation of Human Influenza Virus by High Hydrostatic Pressure Preserves Virus Structure and Membrane Fusion While Conferring Protection to Mice against Infection 10.1371/journal.pone.0080785 2013
The Structural Dynamics of the Flavivirus Fusion Peptide-Membrane Interaction 10.1371/journal.pone.0047596 2012
Mice Vaccination with High Hydrostatic Pressure-Inactivated H3N8 Virus Protects Against Experimental Avian Flu 10.1016/j.provac.2012.04.014 2012
Conformational selection, dynamic restriction and the hydrophobic effect coupled to stabilization of the BIR3 domain of the human X-linked inhibitor of apoptosis protein by the tetrapeptide AVPI 10.1016/j.bpc.2010.08.005 2010
Effects of hydrostatic pressure on the stability and thermostability of poliovirus: A new method for vaccine preservation 10.1016/j.vaccine.2009.06.099 2009
Science and technology to combat dengue virus (Editorial Note) 2009
Conformational changes in bovine lactoferrin induced by slow or fast temperature increases 10.1515/BC.2008.116 2008
Pressure-inactivated yellow fever 17DD virus: Implications for vaccine development 10.1016/j.jviromet.2008.03.002 2008
The Proapoptotic Protein Smac/DIABLO Dimer Has the Highest Stability As Measured by Pressure and Urea Denaturation 10.1021/bi702248n 2008
VP4 Protein from Human Rhinovirus 14 Is Released by Pressure and Locked in the Capsid by the Antiviral Compound WIN 10.1016/j.jmb.2006.11.033 2007
Dissecting the role of protein-protein and protein-nucleic acid interactions in MS2 bacteriophage stability 10.1111/j.1742-4658.2006.05167.x 2006
Structure of a Membrane-binding Domain from a Non-enveloped Animal Virus: INSIGHTS INTO THE MECHANISM OF MEMBRANE PERMEABILITY AND CELLULAR ENTRY 10.1074/jbc.m604689200 2006
Mutations in the hydrophobic core and in the protein-RNA interface affect the packing and pressure stability of MS2 virus capsids 2004
High-pressure applications in medicine and pharmacology 10.1088/0953-8984/16/14/002 2004
Virus stability and protein-nucleic acid interaction as studied by high-pressure effects on Nodaviruses. 2004
Structural Studies of MS2 Bacteriophage Virus Particle Disassembly by Nuclear Magnetic Resonance Relaxation Measurements 2003
Pressure Induces Folding Intermediates that are Crucial for Protein-DNA Recognition and Virus Assembly 2002
Virus Maturation Targets the Protein Capsid to Concerted Disassembly and Unfolding 10.1074/jbc.m910145199 2000
Low Temperature and Pressure Stability of Picornaviruses: Implications for Virus Uncoating 1999
Cold Denaturation of an Icosahedral Virus. The Role of Entropy in Virus Assembly 1995
Arc Repressor Will not Denature Under Pressure in the Absence of Water 1994
Reversible Pressure Dissociation of R17 Bacteriophage: The Individuality of Virus Particles 1993
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Structural and physicochemical studies of the fusion mechanisms and assembly of Hepatitis C Virus 2015
Activity of Bovine Lactoferrin against Arboviruses 2011
Antiviral Activity of Bovine Lactoferrin Against Yellow Fever Virus Infection 2011
Antiviral Activity of Bovine Lactoferrin Against Yellow Fever Virus Infection 2011
Structural Characterization of a Candidate Fusion Peptide of the Hepatitis C Virus 2010
New insights to assist the drug design of IAP antagonists: structural and calorimetric approaches 2010
Structure-function relationship of Hepatitis C Virus core protein and the understanding of viral capsid assembly. 2010
Structural characterization of a candidate fusion peptide of the Hepatitis C Virus 2010
Understanding The Mechanisms Involved On Hepatitis C Virus Assembly 2009
Structural Characterization of a Membrane-Active Region of the Hepatitis C Virus E2 Envelope Glycoprotein 2009
Studies of Structural Stability and Inactivation by High Hydrostatic Pressure of H3N8 2009
Investigation of Cell Death Induced by Yellow Fever Virus 2009
Biophysical Characterization of the Interactions of Flavivirus Fusion Peptides with Micelles and Lipid Bilayer 2009
Apoptosis Induced By Dengue-2 Virus: Investigation Of Mitochondrial Pathway 2009
New Insights to Assist the Drug Design of IAP Antagonists: Structural and Calorimetry Approach 2009
Differential Requirement of Cholesterol over Dengue Virus Infection Cycle 2009
Structural Studies of Human Influenza Virus X-31 2009
Flavivirus Fusion Peptides Interactions with Vesicles and Micelles is Partially Modulated by Charge 2008
AVIAN INFLUENZA VIRUS H3N8: A HIGHLY STABLE VIRUS TO PHYSICAL AND CHEMICAL PERTURBATIONS 2008
APOPTOSIS INDUCED BY FLAVIVIRUSES: INVESTIGATION OF MITOCHONDRIAL PATHWAY 2008
THE LIPIDOME OF CELLS INFECTED WITH ALPHAVIRUSES AND FLAVIVIRUSES: IMPLICATIONS FOR CHOLESTEROL METABOLISM 2008
Caracterização da Interação de Peptídeos de Fusão de Flavivírus com Micelas e Membranas Fosfolipídicas 2008
Flavivirus Fusion Peptides Interaction with Vesicles and Micelles is Partially Modulated by Charge 2008
The Role of Cholesterol and Membrane Fluidity for Dengue Entry 2008
Characterization of the interactions of Flavivirus Fusion Peptides with micelles and phospholipid membranes 2008
Apoptose induzida pelo vírus dengue-2: investigação do papel da via mitocondrial 2008
Apoptosis induced bu Dengue-2 virus: investigation of mitochondrial pathway 2008
Study of Yellow Fever virus-induced cell death 2008
Changes in membrane water content after Cholesterol removal revealed by Laurdan generalized polarization microscopy 2008
HEPATITIS C VIRUS CORE PROTEIN ? DNA INTERACTIONS: IN VITRO ASSEMBLY ANALYSIS 2008
CALORIMETRIC ANALYSIS OF THERMODYNAMIC STABILITY OF THE ISOLATED BIR3-XIAP DOMAIN AND ITS COMPLEX WITH AVPI-SMAC PEPTIDE 2007
CHOLESTEROL IS CRITICAL FOR FLAVIVIRUS FUSION MECHANISMS 2007
AVIAN INFLUENZA VIRUS H3N8 IS HIGHLY STABLE TO PHYSICAL AND CHEMICAL PERTURBATIONS 2007
HEAT-INDUCED CONFORMATIONAL CHANGES OF BOVINE LACTOFERRIN: IMPLICATIONS OF MILK PASTEURIZATION PROCESS 2007
Caracterização Estrutural de Peptídeos de Fusão de Flavivírus e sua Interação com Membranas 2007
Structural Characterization of Flavivirus Fusion Peptides and Its Interaction with Vesicles and Micelles 2007
Structural Characterization of Flavivirus Fusion Peptides and Its Interaction with Vesicles and Micelles 2007
Mudanças conformacionais na lactoferrina bovina induzidas pelo aumento rápido ou lento da temperatura 2007
Stability studies of XIAP-BIR3 domain and its interaction with the tetrapeptide AVPI of the pro-apoptotic protein Smac/DIABLO 2007
Stability studies of XIAP-BIR3 domain and its interaction with the tetrapeptide AVPI of the pro-apoptotic protein Smac/DIABLO 2007
THE ROLE OF CHOLESTEROL AND MEMBRANE FLUIDITY FOR FLAVIVIRUS ENTRY 2007
APOPTOSIS INDUCED BY FLAVIVIRUSES: INVESTIGATION OF MITOCHONDRIAL PATHWAY AND THE PROAPOPTOTIC PROTEIN SMAC/DIABLO 2007
STRUCTURAL CHARACTERIZATION OF FLAVIVIRUS FUSION PEPTIDES AND THEIR INTERACTION WITH VESICLES AND MICELLES 2007
APOPTOSIS INDUCED BY FLAVIVIRUSES: INVESTIGATION OF MITOCHONDRIAL PATHWAY AND THE PROAPOPTOTIC PROTEIN SMAC/DIABLO 2007
APOPTOSE INDUZIDA POR FLAVIVÍRUS: INVESTIGAÇÃO DA VIA MITOCONDRIAL E PARTICIPAÇÃO DA PROTEÍNA SMAC/DIABLO 2007
Reconstituted HDL particles as an alternative acceptor to remove cholesterol in vitro and in vivo 2006
NEW INSIGHTS ON TRANSPORT AND PARTICLE DYNAMICS OBTAINED FROM REAL-TIME 3D TRACKING OF VIRAL PARTICLES IN LIVE CELLS 2006
Structural Stability of XIAP-BIR3 domain and its interaction with the tetrapeptide AVPI of Smac/DIABLO protein: implications in cancer therapy 2006
Heat-induced conformational changes of bovine lactoferrin and its relationship with milk pasteurization process 2006
Importance of the Lipid Composition of target membrane for Flavivirus Fusion Mechanisms 2006
Stability Analysis of the XIAP-BIR3 Domain and its interaction with the peptide AVPI of Smac/DIABLO Protein: Implications in Apoptosis and Anti-Cancer therapy 2006
The Natively Unfolded and Truncated Form of Hepatitis C Virus Core Protein Can Adopt Intermediate Structures Under Several Treatments 2006
Stability Analysis of the XIAP-BIR3 Domain and its interaction with the peptide AVPI of Smac/DIABLO Protein: Implications in Apoptosis and Anti-Cancer therapy 2006
The role of cholesterol for Dengue virus fusion mechanisms 2006
REAL-TIME 3D TRACKING OF VIRAL PARTICLES IN LIVE CELLS 2005
NMR as a tool for studying mechanisms of viral infection: solution structures of the fusion domain of the enveloped Ebola virus and of a membrane-binding domain of the non-enveloped Flock House virus 2005
VP4 Protein from Human Rhinovirus 14 is Released by Pressure and Locked in the Capsid by the Antiviral Compound WIN 2005
Structural Changes on Yellow Fever Virus Induced by High Hydrostatic Pressure: Obtention of Inactivated Particles 2005
The Truncated Hepatitis C Virus Core Protein Can Adopt an Intermediate Structure in the Presence of Several Ligands 2005
Pressure Stability of Smac/DIABLO, a Pro-Apoptocic Protein 2005
Virus Stability and Protein-Nucleic Acid Interactions as Studied by High-Pressure Effects on Nodaviruses 2005
Pressure Stability of Smac/Diablo, a Pro-Apoptotic Protein 2005
THE TRUNCATED HEPATITIS C VIRUS CORE PROTEIN CAN ADOPT AN INTERMEDIATE STRUCTURE IN THE PRESENCE OF SEVERAL LIGANDS 2005
VIRUS STABILITY AND PROTEIN-NUCLEIC ACID INTERACTIONS AS STUDIED BY HIGH-PRESSURE EFFECTS ON NODAVIRUSES 2005
STRUCTURAL ANALYSIS OF CHANGES INVOLVED IN THE INACTIVATION OF YELLOW FEVER VIRUS BY HIGH PRESSURE 2005
EFFECTS OF DNA-BINDING ON THE ARC REPRESSOR MUTANT STABILITY 2004
IS HEPATITIS C VIRUS CORE PROTEIN A NATIVELY UNFOLDED PROTEIN? 2004
PRESSURE-INDUCED CHANGES IN THE HUMAN RHINOVIRUS 14 DYNAMICS AND VP4 RELEASE 2004
Stability and Dynamics During Virus Assembly and Maturation Process of Flock House Virus 2004
CONTRIBUTION OF PROTEIN-PROTEIN AND PROTEIN-NUCLEIC ACID INTERACTIONS TO VIRUS STABILITY 2004
INVESTIGATION OF STRUCTURAL STABILITY OF SMAC/DIABLO PROTEIN INVOLVED ON APOPTOSIS AND ITS IMPLICATIONS IN CANCER 2004
High-Pressure Technology in Vaccine Development 2004
Structural Changes of Yellow Fever Virus (YFV) Induced by High Pressure and Chemical Agents 2004
Investigation of Structural Stability of Smac/Diablo Protein Involved on Apoptosis and its Implications in Cancer 2004
Investigation of Structural Stability of Smac/Diablo Protein Involved on Apoptosis and Its Implications in Cancer 2004
Structural Analysis of Hepatitis C Virus (HCV) Core Protein 2004
Stability and Dynamics During Virus Assembly and Maturation process of Flock House Virus 2004
Stability and Dynamics During Virus Assembly and Maturation process of Flock House Virus 2004
Stability and Dynamics During Virus Assembly and Maturation process of Flock House Virus 2004
Study of Fusion Mechanisms and Structural Changes on Yellow Fever Virus Induced by High Hydrostatic Pressure 2004
The HCV 124 1a Core Protein Adopts a Random Structure in Solution and It is Able to Form Capsids in Vitro in the Presence of Poly(GC) DNA 2004
Analysis of Interactions Involved in Bacteriophage MS2 Stability: Comparision Between Different Forms and Changes on Pressure Stability Induced by DNA Binding to Coat Protein 2004
Correlation between nmr solution structure and membrane activity of g1-peptide from the insect flock house virus 2004
Aspectos Estruturais da Proteína Smac/DIABLO: Uma Nova Proteína Reguladora de Apoptose 2003
Stability and Dynamics during virus Assembly and Maturation of Flock House Virus 2003
Structural Aspects of Smac/DIABLO: a novel regulator protein of apoptosis 2003
Pressure- and Drug-Induced Changes in the Dynamics of Human Rhinovirus 14 2003
Investigation of Conformational Changes and Interactions Involved on Bacteriophage MS2 Assembly 2003
Stability studies of Arc repressor: effects of mutations and DNA-binding 2003
Structural studies of MS2 Bacteriophage virus particle disassembly by nuclear magnetic resonance relaxation measurements 2003
Solution structure by NMR of the membrane-binding domain 1-peptide from the insect Flock House Virus: Implications for the mechanism of viral infection 2003
Structural analysis of Hepatitis C virus core protein 2003
Stability and Dynamics During Virus Assembly and Maturation of Flock House Virus 2003
Solution structure by NMR of the membrane-binding domain 1 peptide from the insect Flock House virus: implications for the mechanism of viral infection 2003
Structural Aspects of Smac/DIABLO: A Novel Regulator Protein of Apoptosis 2003
Stability studies of Arc repressor: effects of mutations and DNA-binding 2003
Stability and Dynamics During Virus Assembly and Maturation processes of Flock House Virus 2003
Structural analysis of Hepatitis C virus core protein 2003
Stability and Dynamics During Virus Assembly and Maturation of Flock House Virus 2003
Pressure- and Drug-Induced Changes in the Dynamics of Human Rhinovirus 14 2003
Structural analysis of Hepatitis C virus core protein 2003
Solution structure of the membrane-binding domain gamma1-peptide from the insect virus Flock House: New insights for viral infection 2002
Determinação da estrutura do peptídeo-γ1 do vírus Flock House por RMN: implicações no processo de infecção viral de vírus não envelopados 2002
Stability studies of Arc repressor: effects of mutations and DNA-binding 2002
Studies on protein-protein and protein-nucleic acid interactions involved on MS2 bacteriophage stability 2002
ASPECTOS ESTRUTURAIS DA PROTEÍNA SMAC/DIABLO: UMA NOVA PROTEÍNA REGULADORA DE APOPTOSE. 2002
ESTUDO DAS INTERAÇÕES PROTEÍNA-PROTEÍNA E PROTEÍNA-ÁCIDO NUCLÉICO ENVOLVIDAS NA ESTABILIDADE DO CAPSÍDEO PROTÉICO DO BACTERIÓFAGO MS2 2002
Solution structure of the membrane-binding domain gamma-peptide from the insect virus Flock House: new insights for viral infection 2002
Effects of antiviral drugs on Human Rhinovirus 14 (HRV14) structural stability 2001
Structural analysis of MS2 bacteriophage: identification of the interactions involved on its stability 2001
Effects of antiviral drugs on Human Rhinovirus 14 (HRV14) structural stability. 2001
Structural analysis of MS2 bacteriophage: identification of the interactions involved on its stability 2001
Effects of antiviral drugs on Human Rhinovirus 14 (HRV14) structural stability 2001
Effect of antiviral drugs on Human Rhinovirus 14 (HRV14) structural stability 2000
Protein-protein and protein-RNA interactions involved on MS2 bacteriophage stability 2000
Pressure-induced inactivation of Soybean Lipoxygenase 2000
Effect of antiviral drugs on Human Rhinovirus 14 (HRV14) structural stability. 2000
Protein-protein and protein-RNA interactions involved on MS2 bacteriophage stability 2000
Virus Maturation targets the capsid to concerted disassembly and unfolding 2000
Virus Maturation targets the capsid to concerted disassembly and unfolding 1999
Single mutations on coat protein affect the MS2 bacteriophage stability 1999
Stability of MS2 Bacteriophage: Comparison between Wild-Type and Temperature-Sensitive Mutants 1998
Assembly-Dependent Maturation Cleavage of Nodaviruses Affects the Virus Capsid Stability 1998
Low Temperature and Pressure Stability of Picornaviruses: Implications for Virus Uncoating 1998
Stability of MS2 Bacteriophage: Comparison between Wild-Type and Temperature-Sensitive Mutants 1998
Low Temperature and Pressure Stability of Picornaviruses: Implications for Virus Uncoating 1998
Assembly-Dependent Maturation Cleavage of Nodaviruses Affects the Virus Capsid Stability 1998
Bacteriophage fX174 Stability: Effects of calcium and pH 1997
Calcium- and Proton-induced stabilization of Bacteriophage fX174 as measured by fluorescence spectroscopy 1997
Comparative Studies on Pressure Stability of Picornaviridae measured by Fluorescence Spectroscopy 1997
Structural Changes in Human Rhinovirus 14 Induced by Pressure, Low Temperature, Drug Binding and pH 1996
Characterization of the Conformational States of Cowpea Sever Mosaic Virus by Using Time-Resolved Fluorescence 1996
Stabilization of Bacteriophage fX174 by Calcium and pH 1996
Characterization of the conformational states of Cowpea severe mosaic virus by using Time-Resolved Fluorescence 1996
Effects of High Pressure, Low Temperature and pH on Poliovirus Structure and Viabillity 1995
Studies of Bacteriophage fX174 Disassembly and Reassembly 1995
Effects of Pressure, Low Temperature and pH on Poliovirus Structure and Viability 1995
Effects of Hydrostatic Pressure and Low Temperature on Cowpea Mosaic Virus 1994
Cold Denaturation of Polioviruses under Pressure 1994
Effects of Hydrostatic Pressure and Low Temperature on Cowpea Mosaic Viirus 1994
Effects of Glycerol on Arc Repressor Dissociation 1993
Purification of QB and R17 Bacteriophages by Using Chromatography Methods 1992
Pressure-dissociation of RNA Phages. The Urea-induced Transition from Deterministic to Stochastic Dissociation 1992
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