Heitor Siffert Pereira de Souza
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Faculdade de Medicina
Departamento:
Seção de Atividades Gerenciais FM/CCS
Formação:
-
Cleveland Clinic Foundation
| Pós-Doutorado | 2005 - 2007
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Universidade Federal do Rio de Janeiro
Clínica Médica | Doutorado | 1996 - 1999
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Universidade Federal do Rio de Janeiro
Medicina (Gastroenterologia) | Mestrado | 1991 - 1994
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Universidade Federal Fluminense
Residência Médica | Especialização | 1988 - 1991
-
Universidade Federal do Rio de Janeiro
Faculdade de Medicina | Graduação | 1982 - 1987
Laboratórios:
Nuvens de Palavras:
Artigos:
(81.08% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Clinical factors associated with severity in patients with inflammatory bowel disease in Brazil based on 2-year national registry data from GEDIIB | 10.1038/s41598-024-54332-1 | 2024 |
| Molecular monitoring by CDKN2A/p16INK4A and RB1 gene methylation in breast cancer | 10.1590/1806-9282.20231358 | 2024 |
| hTERT gene methylation in circulating DNA, tumor, and surrounding tissue in breast cancer: a prospective study | 10.1590/1516-3180.2023.0140.r1.04032024 | 2024 |
| Chronic Pancreatitis in a Large Developing Country: Temporal Trends of Over 64,000 Hospitalizations from 2009 to 2019 | 10.1007/s10620-024-08488-5 | 2024 |
| P2X7 Receptor Modulation of the Gut Microbiota and the Inflammasome Determines the Severity of Toxoplasma gondii-Induced Ileitis | 10.3390/biomedicines11020555 | 2023 |
| The Rise of Gastrointestinal Cancers as a Global Phenomenon: Unhealthy Behavior or Progress? | 10.3390/ijerph20043640 | 2023 |
| MIF is essential to the establishment of house dust mite-induced airway inflammation and tissue remodeling in mice | 10.1002/eji.202250016 | 2023 |
| Current overview on hospitalization and surgery in inflammatory bowel disease. | 2023 | |
| Serum Anti-Spike Antibodies Are Not Affected by Immunosuppressants in SARS-CoV-2 Vaccinations Given to Brazilian Patients with Inflammatory Bowel Disease | 10.3390/healthcare11202767 | 2023 |
| Geographic Distribution and Time Trends of Colorectal Cancer in Brazil from 2005 to 2018 | 10.1007/s10620-021-07357-9 | 2022 |
| Geosocial Features and Loss of Biodiversity Underlie Variable Rates of Inflammatory Bowel Disease in a Large Developing Country: A Population-Based Study | 10.1093/ibd/izab346 | 2022 |
| Bioactive Compounds from Pale Ale Beer Powder Attenuate Experimental Colitis in BALB/c Mice | 10.3390/molecules27041194 | 2022 |
| Dysbiosis in Inflammatory Bowel Disease: Pathogenic Role and Potential Therapeutic Targets | 10.3390/ijms23073464 | 2022 |
| Time trends and geographic distribution of hepatocellular carcinoma in Brazil: An ecological study | 10.1097/md.0000000000030614 | 2022 |
| The P2X7 Receptor Promotes Colorectal Inflammation and Tumorigenesis by Modulating Gut Microbiota and the Inflammasome | 10.3390/ijms23094616 | 2022 |
| Fecal calprotectin as a noninvasive test to predict deep remission in patients with ulcerative colitis | 10.1097/MD.0000000000024058 | 2021 |
| Sulforaphane and Albumin Attenuate Experimental Intestinal Ischemia-Reperfusion Injury | 10.1016/j.jss.2021.01.014 | 2021 |
| Serum 1,3-beta-D-glucan as a noninvasive test to predict histologic activity in patients with inflammatory bowel disease | 10.3748/wjg.v27.i9.866 | 2021 |
| Hospitalization and surgery rates in patients with inflammatory bowel disease in Brazil: a time-trend analysis | 10.1186/s12876-021-01781-x | 2021 |
| Clinical and laboratory markers associated with anti-TNF-alpha trough levels and anti-drug antibodies in patients with inflammatory bowel diseases | 10.1097/MD.0000000000019359 | 2020 |
| CXCR4 and MIF are required for neutrophil extracellular trap release triggered by Plasmodium-infected erythrocytes | 10.1371/journal.ppat.1008230 | 2020 |
| Prevalence, Indirect Costs, and Risk Factors for Work Disability in Patients with Crohn?s Disease at a Tertiary Care Center in Rio de Janeiro | 10.1007/s10620-020-06646-z | 2020 |
| Schistosoma mansoni Coinfection Attenuates Murine Toxoplasma gondii-Induced Crohn's-Like Ileitis by Preserving the Epithelial Barrier and Downregulating the Inflammatory Response | 10.3389/fimmu.2019.00442 | 2019 |
| Superiority of Interferon Gamma Assay Over Tuberculin Skin Test for Latent Tuberculosis in Inflammatory Bowel Disease Patients in Brazil | 10.1007/s10620-019-5475-3 | 2019 |
| Abdominal ultrasonography with color Doppler analysis in the assessment of ileal Crohn?s disease: comparison with magnetic resonance enterography | 10.5217/ir.2018.00124 | 2019 |
| Geographic distribution and time trends of esophageal cancer in Brazil from 2005 to 2015 | 10.3892/mco.2019.1842 | 2019 |
| Dietary Composition and Effects in Inflammatory Bowel Disease | 10.3390/nu11061398 | 2019 |
| Protective effect of adipose tissue-derived mesenchymal stromal cells in an experimental model of high-risk colonic anastomosis | 10.1016/j.surg.2019.07.023 | 2019 |
| Changes in the Management of Patients with Crohn?s Disease Based on Magnetic Resonance Enterography Patterns | 10.1155/2019/3467316 | 2019 |
| Network Medicine: A Mandatory Next Step for Inflammatory Bowel Disease | 10.1093/ibd/izx111 | 2018 |
| Damage-associated molecular patterns in inflammatory bowel disease: From biomarkers to therapeutic targets | 10.3748/wjg.v24.i41.4622 | 2018 |
| Rat models of high risk colorectal anastomoses | 10.1590/s0102-865020180100000006 | 2018 |
| Increasing pancreatic cancer is not paralleled by pancreaticoduodenectomy volumes in Brazil: A time trend analysis | 10.1016/j.hbpd.2018.12.007 | 2018 |
| Pancreatic Cancer Incidence and Lethality Rates in Brazil | 10.1097/mpa.0000000000000791 | 2017 |
| P2X7 receptor promotes intestinal inflammation in chemically induced colitis and triggers death of mucosal regulatory T cells | 10.1016/j.bbadis.2017.03.004 | 2017 |
| Diet and microbiota in inflammatory bowel disease: The gut in disharmony | 10.3748/wjg.v23.i12.2124 | 2017 |
| Etiopathogenesis of inflammatory bowel disease | 10.1097/MOG.0000000000000364 | 2017 |
| The socio-economic impact of work disability due to inflammatory bowel disease in Brazil | 10.1007/s10198-017-0896-4 | 2017 |
| The IBD interactome: an integrated view of aetiology, pathogenesis and therapy | 10.1038/nrgastro.2017.110 | 2017 |
| Sulfate-reducing bacteria stimulate gut immune responses and contribute to inflammation in experimental colitis | 10.1016/j.lfs.2017.09.014 | 2017 |
| Immunopathogenesis of IBD: current state of the art | 10.1038/nrgastro.2015.186 | 2016 |
| Gastrospheres of human gastric mucosa cells: an in vitro model of stromal and epithelial stem cell niche reconstruction | 10.14670/HH-11-726 | 2016 |
| Common NOD2/CARD15 and TLR4 Polymorphisms Are Associated with Crohn?s Disease Phenotypes in Southeastern Brazilians | 10.1007/s10620-016-4172-8 | 2016 |
| Neuroimmunomodulation in the Gut: Focus on Inflammatory Bowel Disease | 10.1155/2016/1363818 | 2016 |
| Disruption of the Hedgehog signaling pathway in inflammatory bowel disease fosters chronic intestinal inflammation | 10.1007/s10238-016-0434-1 | 2016 |
| Macrophage migration inhibitory factor promotes eosinophil accumulation and tissue remodeling in eosinophilic esophagitis | 10.1038/mi.2015.6 | 2015 |
| The Role of Innate Immunity Receptors in the Pathogenesis of Inflammatory Bowel Disease | 10.1155/2015/936193 | 2015 |
| Effectiveness of current disinfection procedures against biofilm on contaminated GI endoscopes | 10.1016/j.gie.2015.09.016 | 2015 |
| Prophylactic systemic P2X7 receptor blockade prevents experimental colitis | 10.1016/j.bbadis.2013.10.012 | 2014 |
| Overexpression of ATP-activated P2X7 Receptors in the Intestinal Mucosa Is Implicated in the Pathogenesis of Crohn¿s Disease | 10.1097/01.mib.0000441201.10454.06 | 2014 |
| IL-13R 2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis | 10.1136/gutjnl-2013-305671 | 2014 |
| Interleukin-33 and Inflammatory Bowel Diseases: Lessons from Human Studies | 10.1155/2014/423957 | 2014 |
| Thiopurine-methyltransferase variants in inflammatory bowel disease: Prevalence and toxicity in Brazilian patients | 2014 | |
| Heparanase expression and localization in different types of human lung cancer | 10.1016/j.bbagen.2014.04.010 | 2014 |
| Ecological study of gastric cancer in Brazil: Geographic and time trend analysis | 10.3748/wjg.v20.i17.5036 | 2014 |
| Multidrug resistance 1 gene polymorphisms may determine Crohn's disease behavior in patients from Rio de Janeiro | 10.6061/clinics/2014(05)06 | 2014 |
| Cell Death and Inflammatory Bowel Diseases: Apoptosis, Necrosis, and Autophagy in the Intestinal Epithelium | 10.1155/2014/218493 | 2014 |
| FOCAL ENHANCED GASTRITIS AND MACROPHAGE MICROAGGREGATES IN THE GASTRIC MUCOSA: potential role in the differential diagnosis between Crohn?s disease and ulcerative colitis | 10.1590/s0004-28032014000400003 | 2014 |
| Ischemia-reperfusion rat model of acute pancreatitis: protein carbonyl as a putative early biomarker of pancreatic injury | 10.1007/s10238-014-0289-2 | 2014 |
| Crohn's disease activity assessed by doppler sonography: the role of aortic flow parameters | 10.6061/clinics/2013(04)04 | 2013 |
| Inflammasome in Intestinal Inflammation and Cancer | 10.1155/2013/654963 | 2013 |
| Endoluminal ultrasound biomicroscopy as a reliable tool for in vivo assessment of colonic inflammation in rats | 10.1007/s00384-013-1755-0 | 2013 |
| Immunohistochemical Analysis of Retinoblastoma and β-Catenin as an Assistant Tool in the Differential Diagnosis between Crohn's Disease and Ulcerative Colitis | 10.1371/journal.pone.0070786 | 2013 |
| Ascidian (chordate-tunicate) and mammalian heparin enemas attenuate experimental diversion colitis | 10.1016/j.surg.2013.06.057 | 2013 |
| Intraperitoneal but Not Intravenous Cryopreserved Mesenchymal Stromal Cells Home to the Inflamed Colon and Ameliorate Experimental Colitis | 10.1371/journal.pone.0033360 | 2012 |
| Effectiveness of Cissampelos sympodialis and its isolated alkaloid warifteine in airway hyperreactivity and lung remodeling in a mouse model of asthma | 10.1016/j.intimp.2012.03.014 | 2012 |
| Extracellular ATP induces cell death in human intestinal epithelial cells | 10.1016/j.bbagen.2012.08.013 | 2012 |
| Microbiota intestinal | 2012 | |
| Characterizing the Presence and Sensitivity of the P2X7 Receptor in Different Compartments of the Gut | 10.1159/000336628 | 2012 |
| Increased Levels of Survivin, via Association With Heat Shock Protein 90, in Mucosal T Cells From Patients With Crohn's Disease | 10.1053/j.gastro.2012.06.039 | 2012 |
| Oxidative stress fuels Trypanosoma cruzi infection in mice | 10.1172/jci58525 | 2012 |
| Hedgehog Pathway Signaling Regulates Human Colon Carcinoma HT-29 Epithelial Cell Line Apoptosis and Cytokine Secretion | 10.1371/journal.pone.0045332 | 2012 |
| Use of butyrate or glutamine in enema solution reduces inflammation and fibrosis in experimental diversion colitis | 10.3748/wjg.v18.i32.4278 | 2012 |
| MIF Participates in Toxoplasma gondii-Induced Pathology Following Oral Infection | 10.1371/journal.pone.0025259 | 2011 |
| Prognostic Significance of p53 Protein Expression in Early Gastric Cancer | 10.1007/s12253-010-9333-z | 2010 |
| Expression of purinergic receptors and modulation of P2X(7) function by the inflammatory cytokine IFNgamma in human epithelial cells | 10.1016/j.bbamem.2009.03.006 | 2009 |
| Analysis of mutations in TP53, APC, K-ras, and DCC genes in the non-dysplastic mucosa of patients with inflammatory bowel disease | 10.1007/s00384-009-0748-5 | 2009 |
| Unfractionated Heparin and New Heparin Analogues from Ascidians (Chordate-Tunicate) Ameliorate Colitis in Rats | 10.1074/jbc.M807211200 | 2009 |
| NFAT1 transcription factor regulates pulmonary allergic inflammation and airway responsiveness | 10.1165/rcmb.2007-0102OC | 2009 |
| Macrophage migration inhibitory factor is critical to interleukin-5-driven eosinophilopoiesis and tissue eosinophilia triggered by Schistosoma mansoni infection | 10.1096/fj.08-124248 | 2009 |
| Mucosal T Cell Proliferation and Apoptosis in Inflammatory Bowel Disease | 10.2174/138945008784221198 | 2008 |
| Therapeutic and prophylactic thalidomide in TNBS-induced colitis: synergistic effects on TNF-a, IL-12, and VEGF production | 2007 | |
| Perfil celular do escarro induzido e sangue periférico na doença pulmonar obstrutiva crônica | 10.1590/S1806-37132007000500005 | 2007 |
| Quantitative assessment of elastic fibers in chronic obstructive pulmonary disease | 10.1590/S1806-37132007000500004 | 2007 |
| Lung production of platelet-activating factor acetylhydrolase in oleic acid-induced acute lung injury | 10.1016/j.plefa.2007.04.001 | 2007 |
| Enhanced Recruitment of CX3CR1+ T Cells by Mucosal Endothelial Cellâ¿¿Derived Fractalkine in Inflammatory Bowel Disease | 10.1053/j.gastro.2006.10.010 | 2007 |
| Distinct patterns of mucosal apoptosis in H. pylori-associated gastric ulcer are associated with altered FasL and perforin cytotoxic pathways | 2006 | |
| Biochemical and immunohistochemical analysis of glycosaminoglycans of inflamed and non-inflamed intestinal mucosa of patients with Crohn's disease | 10.1007/s00384-004-0677-2 | 2005 |
| Apoptosis in the intestinal mucosa of patients with inflammatory bowel disease: evidence for altered expression of FasL and perforin cytotoxic pathways | 10.1007/s00384-004-0639-8 | 2005 |
| Small bowel of patients with asthma and allergic rhinitis: absence of inflammation despite the presence of major cellular components of allergic inflammation | 2004 | |
| Immunohistochemical Study of Intestinal Eosinophils in Inflammatory Bowel Disease | 10.1097/00004836-200302000-00006 | 2003 |
| Effects of ethanol on gut-associated lymphoid tissues in a model of bacterial translocation: a possible role of apoptosis | 10.1016/S0741-8329(03)00134-4 | 2003 |
| Upper gastrointestinal bleeding in a Brazilian hospital: a retrospective study of endoscopic records | 10.1590/S0004-28032002000200002 | 2002 |
| Apoptose no trato gastrintestinal | 2001 | |
| Gastroenteropatia eosinofílica com comprometimento peritonial | 2000 | |
| Imunologia da mucosa intestinal | 2000 | |
| Endoscopia na hemorragia digestiva alta. Estudo retrospectivo em uma enfermaria de clínica médica. | 2000 | |
| Effects of oral nutritional supplementation on intestinal mucosa of patients with AIDS | 10.1097/00004836-200001000-00015 | 2000 |
| Humoral intestinal immunity in systemic lupus erythematosus | 10.1097/00004836-200001000-00009 | 2000 |
| Small bowel involvement in systemic lupus erythematosus: a morpfhometric and immunohistochemical study | 1999 | |
| The expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease | 1999 | |
| Small intestinal morphology in Dermatitis Herpetiformis:experience of the Federal University Hospital of Rio de Janeiro | 1998 | |
| Esclerose sistêmica: depleção linfocitária na lamina propria de delgado | 1998 | |
| Clinical patterns of diarrhea in AIDS. A retrospective study at Federal University Hospital, Rio de Janeiro | 1998 | |
| AIDS-related chronic diarrhoea in a developing country. A retrospective study | 1997 | |
| Phenotypic analysis of intestinal non-inflamed mucosa in Crohn??s disease | 10.1097/00042737-199606000-00013 | 1996 |
| Estudo da imunidade celular na doença de Crohn | 1995 | |
| Variações do Peso Corporal em Cem Pacientes com Câncer do Estômago | 1985 | |
| Estado nutricional antes do desenvolvimento do carcinoma do estomago | 1985 | |
| Os Primeiros Sintomas e a Queixa Principal de Cem Pacientes com Carcinoma do Estômago | 1984 | |
| Contribuição do Exame Físico para o Diagnóstico do Carcinoma do Estômago | 1984 |
Eventos:
(0.00% eventos com DOI)