Ronaldo da Silva Mohana Borges

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biologia Celular e Parasitária/Biof

ORCID:

https://orcid.org/0000-0002-1796-475X


Formação:

  • The Scripps Research Institute

    | Pós-Doutorado | 2000 - 2003

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 1996 - 2000

  • Universidade Estadual do Norte Fluminense Darcy Ribeiro

    Ciências Biológicas | Especialização | 1994 - 1996

  • Universidade Federal do Rio de Janeiro

    Química | Graduação | 1989 - 1994

  • Escola Técnica Federal de Química Rio de Janeiro

    Química | Ensino Profissional de nível técnico | 1985 - 1988
Laboratórios:
Nuvens de Palavras:
Artigos:

(90.12% artigos com DOI)

Titulo DOI Ano
The acquisition of thin sections of açaí ( Euterpe oleracea Mart.) seed with elevated potassium content for molecular mapping by mass spectrometry imaging 10.1002/rcm.9474 2023
Preparation of Hard Palm Seeds for Matrix-Assisted Laser Desorption/Ionization-Imaging Mass Spectrometry Analysis 10.3791/65650 2023
Liver immunopathogenesis in fatal cases of dengue in children: detection of viral antigen, cytokine profile and inflammatory mediators 10.3389/fimmu.2023.1215730 2023
Diabetogenic viruses: linking viruses to diabetes mellitus 10.1016/j.heliyon.2023.e15021 2023
Deep branch of the radial nerve: effect of pronation/supination on longitudinal nerve alignment 10.1007/s00256-023-04332- 2023
Primary infection of BALB/c mice with a dengue virus type 4 strain leads to kidney injury 10.1590/0074-02760220255 2023
Peripheral nervous system is injured by neutrophil extracellular traps ( NETs ) elicited by nonstructural ( NS ) protein-1 from Zika virus 10.1096/fj.202201904r 2023
Antiviral, Cytoprotective, and Anti-Inflammatory Effect of Ampelozizyphus amazonicus Ducke Ethanolic Wood Extract on Chikungunya Virus Infection 10.3390/v15112232 2023
Increased circulating levels of High Mobility Group Box 1 (HMGB1) in acute-phase Chikungunya virus infection: Potential disease biomarker 10.1016/j.jcv.2021.105054 2022
Hyperglycemia alters N-glycans on colon cancer cells through increased production of activated monosaccharides 10.1007/s10719-022-10057-9 2022
Cytokines and inflammatory mediators: Markers involved in interstitial damage to the pancreas in two dengue fever cases associated with acute pancreatitis 10.1371/journal.pone.0262785 2022
Immunogenicity of SARS-CoV-2 Trimeric Spike Protein Associated to Poly(I:C) Plus Alum 10.3389/fimmu.2022.884760 2022
Phenolic Profile and Antioxidant Properties in Extracts of Developing Açaí ( Euterpe oleracea Mart.) Seeds 10.1021/acs.jafc.2c07028 2022
Immunopathology of Renal Tissue in Fatal Cases of Dengue in Children 10.3390/pathogens11121543 2022
Enzymatic and structural properties of human glutamine:fructose-6-phosphate amidotransferase 2 (hGFAT2) 10.1074/jbc.ra120.015189 2021
GD3 synthase deletion alters retinal structure and impairs visual function in mice 10.1111/jnc.15443 2021
ApoA1 neutralizes pro-inflammatory effects of Dengue virus NS1 protein and modulates the viral immune evasion 10.1128/jvi.01974-20 2021
The immunodominant antibody response to Zika virus NS1 protein is characterized by cross-reactivity to self 10.1084/jem.20210580 2021
Morphological Aspects and Viremia Analysis of BALB/c Murine Model Experimentally Infected with Dengue Virus Serotype 4 10.3390/v13101954 2021
Overview on Chikungunya Virus Infection: From Epidemiology to State-of-the-Art Experimental Models 10.3389/fmicb.2021.744164 2021
Inflammatory signaling in dengue-infected platelets requires translation and secretion of nonstructural protein 1 10.1182/bloodadvances.2019001169 2020
Chemical characterization, antioxidant and antimicrobial activities of açaí seed (Euterpe oleracea Mart.) extracts containing A- and B-type procyanidins 10.1016/j.lwt.2020.109830 2020
Duffy binding-like 1α adhesin from Plasmodium falciparum recognizes ABH histo-blood group saccharide in a type specific manner 10.1016/j.carbpol.2018.11.082 2019
Dengue virus nonstructural 3 protein interacts directly with human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and reduces its glycolytic activity 10.1038/s41598-019-39157-7 2019
Mutations in the dimer interfaces of the dengue virus capsid protein affect structural stability and impair RNA-capsid interaction 10.1038/s41598-019-39185-3 2019
LDI and MALDI-FT-ICR Imaging MS in Cannabis Leaves: optimization and study of spatial distribution of cannabinoids 10.1039/c9ay00226j 2019
Expression of soluble, glycosylated and correctly folded dengue virus NS1 protein in Pichia pastoris 10.1016/j.pep.2019.05.003 2019
Conformational isomerization involving conserved proline residues modulates oligomerization of the NS1 interferon response inhibitor from the syncytial respiratory virus 10.1021/acs.biochem.8b01288 2019
Sequenciamento das regiões F(ab)-12 LC e F(ab)-12 HC do anticorpo monoclonal humanizado bevacizumabe: um estudo multicêntrico 2019
Dengue infection in mice inoculated by the intracerebral route: neuropathological effects and identification of target cells for virus replication 10.1038/s41598-019-54474-7 2019
Identification and validation of specific B-cell epitopes of hantaviruses associated to hemorrhagic fever and renal syndrome 10.1371/journal.pntd.0007915 2019
Molecular and functional characterization of single-box high-mobility group B (HMGB) chromosomal protein from Aedes aegypti 10.1016/j.gene.2018.05.103 2018
BALB/c mice infected with DENV-2 strain 66985 by the intravenous route display injury in the central nervous system 10.1038/s41598-018-28137-y 2018
Pregnant women co-infected with HIV and Zika: Outcomes and birth defects in infants according to maternal symptomatology 10.1371/journal.pone.0200168 2018
Characterisation of an ABC transporter of a resistant Candida glabrata clinical isolate 10.1590/0074-02760170484 2018
The Complement System in Flavivirus Infections 10.3389/fmicb.2017.00213 2017
The flavivirus capsid protein: Structure, function and perspectives towards drug design 10.1016/j.virusres.2016.10.005 2017
Systems Biology Reveals NS4B-Cyclophilin A Interaction: A New Target to Inhibit YFV Replication 10.1021/acs.jproteome.6b00933 2017
Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway 10.1038/oncsis.2017.2 2017
Isosorbide-based peptidomimetics as inhibitors of hepatitis C virus serine protease 10.1016/j.bmcl.2017.07.027 2017
Evidence of dengue virus replication in a non-traumatic spleen rupture case 10.1007/s00705-017-3527-6 2017
Dengue fatal cases present virus-specific HMGB1 response in peripheral organs 10.1038/s41598-017-16197-5 2017
The distinct C-terminal acidic domains of HMGB proteins are functionally relevant in Schistosoma mansoni 10.1016/j.ijpara.2015.12.007 2016
Inhibition of the membrane attack complex by dengue NS1 through interaction with vitronectin and terminal complement proteins 10.1128/jvi.00912-16 2016
Dengue virus NS1 protein modulates cellular energy metabolism by increasing glyceraldehyde-3-phosphate dehydrogenase activity 10.1128/jvi.01342-15 2015
Dengue Virus Capsid Protein Interacts Specifically with Very Low Density Lipoproteins 10.1016/j.nano.2013.06.004 2014
Recombinant dengue 2 virus NS3 protein conserves structural antigenic and immunological properties relevant for dengue vaccine design 10.1007/s11262-014-1087-3 2014
Assessing Positivity and Circulating Levels of NS1 in Samples from a 2012 Dengue Outbreak in Rio de Janeiro, Brazil 10.1371/journal.pone.0113634 2014
pH-Dependent Conformational Changes in the HCV NS3 Protein Modulate Its ATPase and Helicase Activities 10.1371/journal.pone.0115941 2014
Novel isomannide-based peptide mimetics containing a tartaric acid backbone as serine protease inhibitors 10.1007/s00044-014-1058-1 2014
Structural insights into the stabilization of the human immunodeficiency virus type 1 capsid protein by the cyclophilin-binding domain and implications on the virus cycle 10.1016/j.bbapap.2014.12.008 2014
High Mobility Group Box 1 Protein as an Auxiliary Biomarker for Dengue Diagnosis 10.4269/ajtmh.2012.12-0619 2013
Mapping the Interactions of Dengue Virus NS1 Protein with Human Liver Proteins Using a Yeast Two-Hybrid System: Identification of C1q as an Interacting Partner 10.1371/journal.pone.0057514 2013
Role of the Acidic Tail of High Mobility Group Protein B1 (HMGB1) in Protein Stability and DNA Bending 10.1371/journal.pone.0079572 2013
Intracellular Nucleic Acid Delivery by the Supercharged Dengue Virus Capsid Protein 10.1371/journal.pone.0081450 2013
Synthetic 1,4-Pyran Naphthoquinones Are Potent Inhibitors of Dengue Virus Replication 10.1371/journal.pone.0082504 2013
Dengue Virus Capsid Protein Binding to Hepatic Lipid Droplets (LD) Is Potassium Ion Dependent and Is Mediated by LD Surface Proteins 10.1128/JVI.06796-11 2012
Novel peptide mimetics based on N-protected amino acids derived from isomannide as potential inhibitors of NS3 serine protease of Hepatitis C virus 2012
The disordered N-terminal region of dengue virus capsid protein contains a lipid-droplet-binding motif 10.1042/BJ20112219 2012
Elevated serum levels of high mobility group box 1 (HMGB1) protein in dengue-infected patients are associated with disease symptoms and secondary infection 10.1016/j.jcv.2012.07.010 2012
The Dengue Vector Aedes aegypti Contains a Functional High Mobility Group Box 1 (HMGB1) Protein with a Unique Regulatory C-Terminus 10.1371/journal.pone.0040192 2012
Polyclonal antibodies against properly folded Dengue virus NS1 protein expressed in E. coli enable sensitive and early dengue diagnosis 10.1016/j.jviromet.2011.04.029 2011
Characterization of a porin channel in the endosymbiont of the trypanosomatid protozoan Crithidia deanei 10.1099/mic.0.049247-0 2011
Induction of a Protective Response in Mice by the Dengue Virus NS3 Protein Using DNA Vaccines 10.1371/journal.pone.0025685 2011
Interaction of the dengue virus fusion peptide with membranes by NMR: the essential role of the envelope protein Trp101 for membrane fusion 10.1016/j.jmb.2009.07.035 2009
The Major Surface Carbohydrates of the Echinococcus granulosus Cyst: Mucin-Type O -Glycans Decorated by Novel Galactose-Based Structures 10.1021/bi901112q 2009
Interaction between dengue virus fusion peptide and lipid bilayers depends on peptide clustering 10.1080/09687680701633091 2008
Regulation of Escherichia coli SOS mutagenesis by dimeric intrinsically disordered umuD gene products 10.1073/pnas.0706067105 2008
Characterization of two heparan sulphate-binding sites in the mycobacterial adhesin Hlp 10.1186/1471-2180-8-75 2008
Characterization of glycoinositolphosphoryl ceramide structure mutant strains of Cryptococcus neoformans 10.1093/glycob/cwm030 2007
Structural characterization of partially folded intermediates of apomyoglobin H64F 10.1110/ps.073187208 2007
Tetramerization of the LexA Repressor in Solution: Implications for Gene Regulation of the E.coli SOS System at Acidic pH 10.1016/j.jmb.2006.03.069 2006
Specificity in DNA recognition by a peptide from papillomavirus E2 protein 10.1016/j.febslet.2006.02.047 2006
Cardiolipin in Hydrogenosomes: Evidence of Symbiotic Origin 10.1128/EC.5.4.784-787.2006 2006
Structural Characterization of Unfolded States of Apomyoglobin using Residual Dipolar Couplings 10.1016/j.jmb.2004.05.022 2004
Pressure induces folding intermediates that are crucial for protein-DNA recognition and virus assembly 2002
Virus Maturation Targets the Capsid to Concerted Disassembly and Unfolding 2000
LexA Repressor Forms Stable Dimers in Solution: The Role of Specific DNA in Targeting Protein-Protein Interactions 2000
Folding of a Pressure-Denatured Model Protein 1999
Protein Folding in the Absence of Chemical Denaturants. Reversible Pressure Denaturation of the Noncovalent Complex Formed by the Association of Two Protein Fragments 1999
Carboxyl-Terminal Sequencing: new C-Terminal Peptidyl-Thiohydantoins Formation Conditions 1998
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Thermodynamic Characterization of Hepatitis C Vírus NS5B Protein Ecpressed In e. Coli 2012
Promising new compounds against Hepatitis C virus NS3 helicase 2012
Dengue Virus Non Structural 1 (NS1) protein interacts with human acute phase proteins. 2012
The non-structural 3 (NS3) protein of dengue virus interacts with human liver proteins. 2010
Cloning, expression and thermodynamic characterization of hepatitis C virus NS5b protein in E. coli 2010
Thermodynamic studies of human high mobility group box 1 proteins (HMGB1). 2010
Dengue virus NS1 polyclonal antibodies: a useful tool for development of diagnostic kits 2010
Characterization of the interaction of the dengue virus C protein with lipid droplets 2010
Purification and thermodynamic characterization of capsid protein from dengue virus type 2 (DEN2C) 2010
Inhibition of hepatitis C virus ATPase/Helicase NS domain by triazole derivative 2010
The characterization of a porin-like protein in the bacterium of Crithidia deanei offers new clues on the symbiosis in trypanosomatids 2010
The Non-Structural 3 (NS3) Protein of Dengue Virus Interacts with Human Liver Proteins. 2010
Purification and Thermodynamic Characterization of Capsid Protein from Dengue Virus Type 2 (DEN2C) 2010
Recombinant DENV2 NS1 Protein Expressed in E. coli Maintains its Structural Properties and Generates Polyclonal Antibodies Useful for Dengue Diagnosis 2010
Triagem de compostos inibidores da atividade ATPase da proteína recombinante não estrutural 3 (NS3) do vírus da Hepatite C (HCV) 2010
Fatores da glia de retina mantém a sobrevida de neurônios sensoriais de embriões de aves 2010
Estudos Termodinâmicos das Proteínas do Grupo de Alta Mobilidade Humana 2010
Clonagem, Expressão e Caracterização Termodinâmica da NS5B do HCV 2010
Caracterização da Interação Entre a Proteína C do Virus da Dengue e os Corpúsculos Lipídicos 2010
Identification of protein interactions between NS1 DENV-2 and human liver proteins 2010
Properly folded dengue virus NS1 protein from E.coli generates polyclonal antibodies that enable sensitive and early dengue diagnosis 2010
Recombinant DENV2 NS1 protein expressed in E. coli maintains its structural properties and generates polyclonal antibodies useful for dengue diagnosis 2010
Structural and thermodynamic characterization of high mobility group proteins (HMGB1) 2009
Cloning, expression and thermodynamic characterization of dengue virus 2 NS5 methyltransferase domain (CAP) expressed in E. coli 2009
Expression, purification and thermodynamic characterization of the helicase and protease domains of the HCV NS3 protein 2009
Policlonal antibodies generated from recombinant dengue virus NS1 protein: a useful tool for development of diagnostic kits 2009
Purification and thermodynamic characterization of capsid protein from dengue virus type 2 (DEN2C) 2009
Requisitos Estruturais para Fusão de Vírus Sindbis (SinV) e Peptídeo de Fusão SinV com Diferentes Vesículas Lipídicas 2009
Expressão, Purificação e Caracterização Termodinâmica dos Domínios Helicase e Protease da Proteína Não-Estrutural 3 (NS3) do Vírus da Hepatite C (HCV). 2009
Clonagem, Expressão e Caracterização Termodinâmica da Proteína Não Estrutural NS5 do Vírus da Dengue Sorotipo 2 Expressa em E. coli 2009
Caracterização Estrutural e Termodinâmica de Proteínas do Grupo de Alta Mobilidade Box 1 2009
Caracterização Bioquímica da Proteína NS1 do Vírus da Dengue Sorotipo 2 2009
Thermodynamic Studies of Recombinant Dengue Virus NS1 Protein 2009
Characterization of Crithidia deanei endosymbiont porin: the prokariotic origin of bacterial outer membrane 2009
Expression in human lesions and refolding of a glycoprotease of Mycobacterium leprae 2008
The presence of a porin-like protein reveals the origin of the endosymbiont envelope in Crithidia deanei 2008
Large scale purification and thermodynamic characterization of UmuC from Escherichia coli 2008
Structural and thermodynamic characterization of high mobility group proteins (HMGB1) 2008
Cloning, expression, purification and activity of recombinant NS2B/NS3 serine protease of dengue virus type 2 2008
Purification and thermodynamic characterization of capsid protein from dengue virus type 2 2008
Cloning, expression and thermodynamic characterization of dengue virus 2 nonstructural protein 5 (NS5) expressed in E. coli 2008
Novel structural and themodynamic insights on dengue virus fusion. Searching for new potential targets for rational drug design 2008
Enzymatic activity and thermodynamic characterization of full-length NS3 protein, NS3helicase and NS3protease domains of the dengue virus type 2 2008
Proteomic study of HepG2 cell extract during dengue virus infection 2008
Purificação e caracterização termodinâmica da proteína capsídica do vírus da dengue tipo 2 2008
Clonagem e caracterização funcional da glicoproteína E do vírus da dengue sorotipo 2 expressa em Pichia pastoris 2008
Clonagem, expressão e caracterização termodinâmica da proteína não-estrutural NS5 do vírus da dengue sorotipo 2 expressa em E. coli 2008
Clonagem, expressão, purificação e atividade proteolítica do recombinante serino protease NS2B/NS3 do vírus da dengue do tipo 2 2008
Caracterização estrutural e termodinâmica de proteínas do grupo de alta mobilidade 2008
Purification and thermodynamic characterization of capsid protein from dengue virus type 2 (DEN2C) 2008
Cloning, expression, purification and activity of recombinant NS2B/NS3 serine protease of dengue virus type 2 2008
Novel structural and themodynamic insights on dengue virus fusion. Searching for new potential targets for rational drug design. 2008
Endosymbiosis in Trypanosomatids: the finding origin of the outer membrane in the symbiotic bacterium 2008
Expression and functional characterization of dengue virus 2 immunogenic nonstructural protein 1 (NS1) in Pichia pastoris 2007
Revelando o mecanismo de interação do peptídeo de fusão do vírus da dengue com vesículas lipídicas. 2007
Clonagem e caracterização funcional da glicoproteína E do vírus da dengue sorotipo 2 expressa em Pichia pastoris 2007
Resposta do Sistema SOS de Escherichia coli a Estresse Ácido 2007
Purificação e Caracterização dos Polissacarídeos Capsulares de Cepas Selvagens e Mutantes de Cryptococcus neoformans var. neoformans 2007
Clonagem, purificação e expressão da proteína quimérica NS2BCF40glyNS3Pro do vírus da Dengue 2 2007
Expression and Functional Characterization of dengue Virus 2 Immunogenic Nonstructural Protein 1 (NS1) in Pichia pastoris. 2007
Biochemical and molecular assays reveal the outer membrane origin in the Crithidia deanei endosymbiont 2007
Enzymatic Activity and Thermodynamic Characterization of NS3 Helicase/NTPase Protein of the Dengue Virus Type 2 2006
Cloning, Expression and Functional Characterization of Dengue Virus 2 Glycoprotein E Expressed in Pichia pastoris 2006
Proteomic Study of HepG2 Cell Extract During Dengue Virus Infection 2006
The envelope composition of a symbiotic bacterium reveals news aspects of the endosymbiosis in trypanosomatid protozoa. 2006
Revealing the Mechanism of Interaction Between Dengue Virus Fusion Peptide and Lipid Vesicles 2006
Structural characterization of dengue virus 2 fusion peptide bound to detergent micelles by NMR 2006
Composição Protéica do Envoltório do Endosimbionte de Crithidia deanei 2006
Clonagem e Caracterização Funcional da Glicoproteína E do Vírus da Dengue Sorotipo 2 Expressa em Pichia pastoris 2006
Análise Proteômica do Extrato de Células HepG2 Durante a Infeção Pelo Vírus Dengue 2 2006
Análise Comparativa da Expressão Geral de mRNA de Células Hepatoma G2 Infectadas Com Vírus Dengue 2 e Caracterização Bioquímica da Enzima NS3 do Vírus da Dengue. 2006
Endosymbiosis in trypanosomatids: the protein composition of the bacterium envelope 2006
Unrevealing novel pathway for DNA recognition by regulatory E2 protein from papillomavirus 2005
Structural characterization of dengue virus 2 fusion peptide bound to detergent micelles 2005
Caracterização estrutural do peptídeo de fusão do vírus da dengue ligado à micelas de detergente 2005
Structural characterization of dengue virus 2 fusion peptide bound to detergent micelles 2005
Structural and thermodynamic characterization of S. mansoni high mobility group (HMG) proteins 2005
Specificity in DNA recognition by peptide from papillomavirus E2 protein 2005
Proteomic analysis of human liver cells infected with dengue virus 2 2005
Mapping the topology of the molten globule state of apomyoglobin by residual dipolar couplings and spin-labeled side chains 2005
Caracterização estrutural da proteína HMGB1 (High Mobility Group Protein da Família B1) de Schistosoma mansoni 2005
Mapping the topology of the molten globule state of apomyoglobin by residual dipolar couplings and spin-labeled side chains 2004
Characterization of the wild type and mutant forms of Vibrio cholerae response regulator phoB expressed in Escherichia coli 2004
Characterization of oligomeric states of LexA repressor of the SOS system of E. coli at low pH 2004
LexA repressor does not unfold at low pH and forms stable tetramers in solution 2004
Determinação da estrutura tridimensional do peptídeo de fusão do vírus da dengue 2004
Caracterização estrutural e termodinâmica de proteínas com motivos de alta mobilidade (high mobility group ou HMG) de espécies de Schistosoma 2004
Mapping the topology of unfolded and partially folded proteins by residual dipolar couplings 2003
Mapping the topology of unfolded and partially folded proteins by residual dipolar couplings 2003
Characterization of the topology of apomyoglobin molten globule by multidimensional NMR spectroscopy 2002
Characterization of partly folded states of apomyoglobin by multidimensional NMR spectroscopy 2001
NMR-characterization of unfolded and partially folded states of the fast folding myoglobin mutant H64F 2001
Energetics and dynamics of the chymotrypsin inhibitor-2 as determined by time-resolved fluorescence decays 2000
Structural analysis at low pH of the LexA protein - repressor of the SOS system of Escherichia coli 2000
Structural Aspects of the LexA Repressor of E. coli and its Interactions with DNA Operators 1999
Virus Maturation Targets the Capsid to Concerted Disassembly and Unfolding 1999
Maturation Cleavage of Nodavirus Affects the Virus Capsid Stability Under Pressure and Urea Treatment 1998
Folding Mechanism of a Complex Formed by the Association of two Protein Fragments from High Pressure Experiments 1998
Thermodynamic Characterization of the LexA - Repressor Protein of the SOS Regulon of E. coli - and of its Binding to recA Operator 1998
Carboxy-Terminal Sequencing: New C-Terminal Peptidyl-Thiohydantoin Formation Conditions 1997
Pressure Unfolding of a Non-Covalent Complex Product of the Association of two Complementary Protein Fragments 1997
Carboxy-Terminal Sequencing: New C-Terminal Peptidyl-Thiohydantoin Formation Conditions 1997
Sequencing of Peptide and Protein from the Carboxy-Terminus 1996
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