Lucio Mendes Cabral

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Farmácia

Departamento:

Departamento de Fármacos e Medicamentos

ORCID:

não disponível no Lattes


Formação:
  • Università degli Studi di Roma La Sapienza

    Total Quality Control And Gmpc | Especialização | 1998 - 1998
  • Università degli Studi di Roma La Sapienza

    | Pós-Doutorado | 1998 - 1999
  • Universidade Federal do Rio de Janeiro

    Química de Produtos Naturais | Doutorado | 1993 - 1996
  • Universidade Federal do Rio de Janeiro

    Química | Mestrado | 1991 - 1993
  • Universidade Federal do Rio de Janeiro

    Farmacêutico Industrial | Graduação | 1986 - 1990
Laboratórios:
Nuvens de Palavras:
Artigos:

(87.61% artigos com DOI)

Titulo DOI Ano
Design, synthesis and antiproliferative evaluation of new acridine-thiosemicarbazone derivatives as topoisomerase IIα inhibitors 10.1016/j.rechem.2024.101371 2024
Synthesis, in silico, and in vitro Evaluation of 7-chloro-quinolines Designed as Myeloperoxidase Inhibitors 10.1016/j.molstruc.2024.138528 2024
Evaluation of Silybin Nanoparticles against Liver Damage in Murine Schistosomiasis mansoni Infection 10.3390/pharmaceutics16050618 htt 2024
An In Silico Analysis of Genetic Variants and Structural Modeling of the Human Frataxin Protein in Friedreich?s Ataxia 10.3390/ijms25115796 2024
Solid Lipid Nanoparticles Based on Babassu Oil and Copaiba Oleoresin: A Promising Approach for Prostate Cancer Therapy 10.3390/nano14121014 2024
Identification and characterization of Rotigotine degradation products by HPLC coupled DAD and CAD detectors and HRMS through Q-Orbitrap and electrospray ionization 10.1016/j.xphs.2024.05.028 2024
Development of formulation containing caffeine for Dermal Delivery 10.1111/ics.12841 2023
Physiologically-based pharmacokinetics modeling of Semaglutide in children and adolescents with healthy and obese body weights 10.1111/bcp.15816 2023
In vitro and in situ caries-preventive effect of a new combined fluoride and calcium experimental nanocomposite solution. 10.1590/0103-6440202305460 2023
In vivo evaluation of time-dependent antithrombotic effect of rivaroxaban-loaded poly(lactic-co-glycolic acid)/sodium lauryl sulfate or didodecyl dimethylammonium bromide nanoparticles in Wistar rats 10.1016/j.ejpb.2023.07.016 2023
Chitosan-based hydrotalcite nanostructured membranes containing sodium alendronate for guided bone regeneration therapy 10.7324/japs.2023.40064 2023
Use of in silico and in vitro methods as a potential new approach methodologies (NAMs) for (photo)mutagenicity and phototoxicity risk assessment of agrochemicals 10.1016/j.scitotenv.2023.167320 2023
Use of In silico Methodologies to Predict the Bioavailability of OralSuspensions: A Regulatory Approach 10.2174/0113816128257028231030113156 2023
Applying in silico Approaches to Nanotoxicology: Current Status and Future Potential 10.1016/j.comtox.2022.100225 2022
Chemical profiling of Cannabis varieties cultivated for medical purposes in southeastern Brazil 10.1016/j.forsciint.2022.111309 2022
Development of Novel Montmorillonite-Based Sustained Release System for Oral Bromopride Delivery. 10.1016/j.ejps.2022.106222 2022
Preparation and evaluation of red propolis and nystatin cyclodextrin inclusion complexes against oral microbiome opportunistic microorganisms 10.1590/fst.118022 2022
Alternative Methods for Pulmonary-Administered Drugs Metabolism: a Breath of Change 10.2174/1389557522666220620125623 2022
Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine-Thiosemicarbazone Derivatives 10.3390/ph15091098 2022
Copaiba Oil Resin Exerts an Additive Effect to Babassu Oil on Behavioral Changes in Human Endometriotic Cell Cultures 10.3390/ph15111414 2022
Macitentan: An overview of its degradation products, process-related impurities, and in silico toxicity 10.1016/j.comtox.2022.100255 2022
Development of a validation protocol method for nucleic acid testing to detect human immunodeficiency virus, hepatitis C virus, and hepatitis B virus 10.1590/0001-3765202220211321 2022
Application of in silico methods in clinical research and development of drugs and their formulation: A scoping review 10.7324/japs.2023.87792 2022
Development and validation of a fast HPLC method for methyldopa enantiomers using superficially porous particle based macrocyclic glycopeptide stationary phase 10.1016/j.microc.2021.105957 2021
Development of transdermal based hydrogel formulations of vinorelbine with an evaluation of their in vitro profiles and activity against melanoma cells and in silico prediction of drug absorption 10.1016/j.jddst.2021.102449 2021
Stability Indicating Methods for Determination of Third Generation Antiepileptic Drugs and Their Related Substances 10.1080/10408347.2021.1890544 2021
Clofazimine functionalized polymeric nanoparticles for brain delivery in the tuberculosis treatment 10.1016/j.ijpharm.2021.120655 2021
Benign prostatic hyperplasia therapy through liquisolid technology composed of polymer-layered nanocomposites based on silicate that contain babassu oil and copaiba oil-resin 10.1016/j.jddst.2021.102586 2021
Lopinavir/Ritonavir: A Review of Analytical Methodologies for the Drug Substances, Pharmaceutical Formulations and Biological Matrices 10.1080/10408347.2021.1920364 2021
Evaluation of chloroquine and hydroxychloroquine as ACE-2 Inhibitors By In Silico Approaches: Cardiac Arrhythmia Cause? 10.1016/j.molstruc.2021.130946 2021
Is zebrafish (Danio rerio) water tank model applicable for the assessment of glucocorticoids metabolism? The budesonide assessment 10.1016/j.jchromb.2021.122826 2021
Development of rivaroxaban microemulsion-based hydrogel for transdermal treatment and prevention of venous thromboembolism 10.1016/j.colsurfb.2021.111978 2021
Antimycobacterial and anti-inflammatory activities of thiourea derivatives focusing on treatment approaches for severe pulmonary tuberculosis 10.1016/j.bmc.2021.116506 2021
In vitro effect of experimental nanocomposites solutions on the prevention of dental caries around orthodontic brackets 10.1590/0103-6440202104331 2021
Full-factorial design for statistical planning of attritor milling parameters and evaluation of effects on particle size and structure of sodium-montmorillonite 10.1088/2631-8695/ab7d85 2020
Characterization and effect of nanocomplexed fluoride solutions on the inhibition of enamel demineralization created by a multispecies cariogenic biofilm model 10.1007/s00784-020-03261-0 2020
Forced degradation studies of norepinephrine and epinephrine from dental anesthetics: Development of stability-indicating HPLC method and in silico toxicity evaluation 10.1002/bmc.4832 2020
Insights on chemical-biological correlations learned from investigations on the sulfated galactan from the marine alga Bothryocladia occidentalis 10.1016/j.ijbiomac.2020.04.085 2020
Development of inhaled formulation of modified clofazimine as an alternative to treatment of tuberculosis 10.1016/j.jddst.2020.101805 R 2020
Comparative Effect of Calcium Mesoporous Silica Versus Calcium and/or Fluoride Products Against Dental Erosion 10.1590/0103-6440202002557 2020
Vancomycin-loaded nanoparticles against vancomycin intermediate and methicillin resistant Staphylococcus aureus strains 10.1088/1361-6528/ab97d7 2020
In Silico studies of novel Sildenafil self-emulsifying drug delivery system absorption improvement for pulmonary arterial hypertension 10.1590/0001-3765202020191445 2020
Nanoparticles Loaded with a New Thiourea Derivative: Development and In Vitro Evaluation Against Leishmania Amazonensis 10.2174/1567201817666200704132348 2020
Effects of a novel roflumilast and formoterol fumarate dry powder inhaler formulation in experimental allergic asthma 10.1016/j.ijpharm.2020.119771 2020
The use of a new calcium mesoporous silica nanoparticle versus calcium and/or fluoride products in reducing the progression of dental erosion 10.1590/1678-7757-2020-0131 2020
Laser therapy increases the proliferation of preosteoblastic MC3T3-E1 cells cultured on poly(lactic acid) films 10.1002/term.3134 2020
An attempt to chemically state the cross-talk between monomers of COX homodimers by double/hybrid inhibitors mofezolac-spacer-mofezolac and mofezolac-spacer-arachidonic acid 10.1016/j.ejmech.2020.112919 2020
Insights and controversies on sunscreen safety 10.1080/10408444.2020.1826899 2020
Rotigotine: A Review of Analytical Methods for the Raw Material, Pharmaceutical Formulations and Its Impurities 10.1093/jaoacint/qsaa145 2020
Tobramycin: A review of detectors used in analytical approaches for drug substance, its impurities and in pharmaceutical formulation 10.1016/j.microc.2020.105658 2020
Effect of xylitol tablets with and without red propolis on salivary parameters, dental biofilm and sensory acceptability of adolescents: a randomized crossover clinical trial 10.1080/08927014.2020.1858063 2020
Ezetimibe: A Review of Analytical Methods for the Drug Substance, Pharmaceutical Formulations and Biological Matrices 10.1080/10408347.2020.1857222 2020
Characterization and in vitro antitumor activity of polymeric nanoparticles loaded with Uncaria tomentosa extract 10.1590/0001-3765202020190336 2020
In Vitro-In Vivo Correlation for Desvenlafaxine Succinate Monohydrate Extended Release Tablets 10.1208/s12249-020-01740-x 2020
Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability 10.1016/j.ejmech.2018.12.029 2019
Development of USP Apparatus 3 Dissolution Method with IVIVC for Extended Release Tablets of Metformin Hydrochloride and Development of a Generic Formulation 10.1248/cpb.c18-00579 2019
In Situ Cocrystallization of Dapsone and Caffeine during Fluidized Bed Granulation Processing 10.1208/s12249-018-1228-4 2019
Photoprotection assessment of olive (Olea europaea L.) leaves extract standardized to oleuropein: In vitro and in silico approach for improved sunscreens 10.1016/j.jphotobiol.2019.03.003 2019
Evaluation of the Effectiveness of the Notification Process in the Area of Health Products 10.1016/j.hlpt.2019.03.005 2019
Experimental composites containing quaternary ammonium methacrylates reduce demineralization at enamel-restoration margins after cariogenic challenge 10.1016/j.dental.2019.05.021 2019
Cytotoxic and antibacterial effect of a red propolis mouthwash, with or without fluoride, on the growth of a cariogenic biofilm 10.1016/j.archoralbio.2019.104512 2019
Evaluation of the in vitro release and permeation of Cordia verbenacea DC essential oil from topical dosage forms 10.1016/j.jddst.2019.101173 2019
Oral pentamidine-loaded poly(d,l-lactic-co-glycolic) acid nanoparticles: an alternative approach for leishmaniasis treatment 10.1088/1361-6528/ab373e 2019
Self-cured resin modified by quaternary ammonium methacrylates and chlorhexidine: Cytotoxicity, antimicrobial, physical, and mechanical properties 10.1016/j.dental.2019.10.007 2019
Molecular modeling for the investigation of UV absorbers for sunscreens: Triazine and benzotriazole derivatives 10.1016/j.jphotochem.2017.12.036 2018
Development and validation of a stability-indicating HPLC method for topiramate using mixed-mode column and charged aerosol detector 10.1002/jssc.201701340 2018
A promising oral fucoidan-based antithrombotic nanosystem: Development, activity and safety 10.1088/1361-6528/aaae5b 2018
The xylooligosaccharide addition and sodium reduction in requeijão cremoso processed cheese 10.1016/j.foodres.2018.02.018 2018
Development and validation of a RP-HPLC method for Roflumilast and its degradation products 10.1080/10826076.2018.1436067 2018
Synthesis and antitumor evaluation of hybrids of 5,8-dioxo-5,8-dihydroisoquinoline-4-carboxylates and carbohydrates 10.4155/fmc-2017-0173 2018
Cytotoxicity of novel fluoride solutions and their influence on mineral loss from enamel exposed to a Streptococcus mutans biofilm 10.1016/j.archoralbio.2018.04.008 2018
Development and Characterization of Dapsone Cocrystal Prepared by Scalable Production Methods 10.1208/s12249-018-1101-5 2018
Development of a Dissolution Method for Gliclazide Modified-Release Tablets Using USP Apparatus 3 with in Vitro-in Vivo Correlation 10.1248/cpb.c17-00933 2018
Synthesis and evaluation of the cytotoxic activity of Furanaphthoquinones tethered to 1 H -1,2,3-triazoles in Caco-2, Calu-3, MDA-MB231 cells 10.1016/j.ejmech.2018.07.018 2018
A synergistic nanoformulation of babassu and copaiba oils as natural alternative for prevention of benign prostatic hyperplasia 10.1016/j.jddst.2018.07.013 2018
Physicochemical quality profiles of commercial oral tablets and capsules containing lutein - impact of insufficient specific sanitary regulations 10.1590/0001-3765201820170972 2018
Pharmaceutical excipients properties and screw feeder performance in continuous processing lines: a Quality by Design (QbD) approach 10.1080/03639045.2018.1513024 2018
Development of a new formulation of roflumilast for pulmonary drug delivery to treat inflammatory lung conditions 10.1016/j.ijpharm.2018.08.035 2018
Development of a novel nano-biomaterial for biomedical applications 10.1088/2053-1591/aae11b 2018
DIRETRIZES PARA ELABORAÇÃO DE UM PROTOCOLO E RELATÓRIO DE ESTUDO DE DEGRADAÇÃO FORÇADA DE MEDICAMENTOS DE ACORDO COM A RDC 53/2015 10.14450/2318-9312.v30.e3.a2018.pp194-202 2018
Sensitive detection of topiramate degradation products by HPLC-ESI-MS using ion-pairing reagents and polarity switching 10.1002/rcm.8321 2018
Suspected adverse drug reactions reported for Brazilian children: cross-sectional study 10.1016/j.jped.2018.05.019 2018
Development and characterization of poly(lactic-co-glycolic) acid nanoparticles loaded with copaiba oleoresin 10.1080/10837450.2017.1290107 2017
In vitro enamel erosion and abrasion-inhibiting effect of different fluoride varnishes 10.1016/j.archoralbio.2017.01.010 2017
Development of a Discriminative In Vitro Release Test for Rivastigmine Transdermal Patches Using Pharmacopeial Apparatuses: USP 5 and USP 6 10.1208/s12249-017-0738-9 2017
Identification, characterization and in silico ADMET prediction of Roflumilast degradation products 10.1016/j.jpba.2017.02.012 2017
Surface-coated polycaprolactone nanoparticles with pharmaceutical application: Structural and molecular mobility evaluation by TD-NMR 10.1016/j.polymertesting.2017.01.032 2017
Fluoride Varnishes against Dental Erosion Caused by Soft Drink Combined with Pediatric Liquid Medicine 10.1590/0103-6440201701567 2017
Synthesis and mechanistic evaluation of novel N ?-benzylidene-carbohydrazide-1 H -pyrazolo[3,4 -b ]pyridine derivatives as non-anionic antiplatelet agents 10.1016/j.ejmech.2017.04.023 2017
Development and characterization of clay-polymer nanocomposite membranes containing sodium alendronate with osteogenic activity 10.1016/j.clay.2017.06.033 2017
In vitro physiological and antibacterial characterization of ZnO nanoparticle composites in simulated porcine gastric and enteric fluids 10.1186/s12917-017-1101-9 2017
Antibiofilm properties of model composites containing quaternary ammonium methacrylates after surface texture modification 10.1016/j.dental.2017.07.010 2017
Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives 10.1248/cpb.c17-00293 2017
Effect of the inclusion nanocomplex formed of titanium tetrafluoride and β-Cyclodextrin on enamel remineralization 10.4103/jpbs.jpbs_161_16 2017
Physical and chemical properties of model composites containing quaternary ammonium methacrylates 10.1016/j.dental.2017.09.020 2017
Molecular modeling and dynamic simulations of agglutinin-like family members from Candida albicans : New insights into potential targets for the treatment of candidiasis 10.1080/07391102.2017.1417159 2017
Development and Characterization of Nisin Nanoparticles as Potential Alternative for the Recurrent Vaginal Candidiasis Treatment 10.1208/s12249-016-0477-3 2016
Development of a novel dry powder inhalation formulation for the delivery of rivastigmine hydrogen tartrate 10.1016/j.ijpharm.2016.01.066 2016
Antiplatelet pyrazolopyridines derivatives: pharmacological, biochemical and toxicological characterization 10.3109/14756366.2016.1158712 2016
The antihemostatic profile of vitamin C: Mechanisms that underlie the technical application of a physiological molecule 10.2298/abs150413024s 2016
Development and validation of a dissolution test for lutein tablets and evaluation of intestinal permeability 10.1016/j.foodchem.2016.04.081 2016
Development and pharmacological evaluation of in vitro nanocarriers composed of lamellar silicates containing copaiba oil-resin for treatment of endometriosis 10.1016/j.msec.2016.03.094 2016
Design, Synthesis and Evaluation of New Fluoroamodiaquine Analogues 10.1248/cpb.c15-01001 2016
Comparative anatomy and chemical analysis of the vegetative organs of three species of Stigmaphyllon (Malpighiaceae) 10.1016/j.flora.2016.07.001 2016
Targeted Nanosystems to Prostate Cancer 10.2174/1381612822666160715131359 2016
Preparation methods and applications behind alginate-based particles 10.1080/17425247.2016.1214564 2016
New approaches in tail-bleeding assay in mice: improving an important method for designing new anti-thrombotic agents 10.1111/iep.12182 2016
Comparative evaluation of rivastigmine permeation from a transdermal system in the Franz cell using synthetic membranes and pig ear skin with in vivo-in vitro correlation 10.1016/j.ijpharm.2016.08.052 2016
Efavirenz dissolution enhancement III: Colloid milling, pharmacokinetics and electronic tongue evaluation 10.1016/j.ejps.2016.12.032 2016
Design of experiments for the development of poly(d,l-lactide-co-glycolide) nanoparticles loaded with Uncaria tomentosa 10.1007/s11051-015-2883-y 2015
Sodium Montmorillonite/Amine-Containing Drugs Complexes: New Insights on Intercalated Drugs Arrangement into Layered Carrier Material 10.1371/journal.pone.0121110 2015
Topiramate: a review of analytical approaches for biological matrices 10.1002/bmc.3466 2015
Synthesis and Antiplatelet Activity of Antithrombotic Thiourea Compounds: Biological and Structure-Activity Relationship Studies 10.3390/molecules20047174 2015
Computational Studies of Benzoxazinone Derivatives as Antiviral Agents against Herpes Virus Type 1 Protease 10.3390/molecules200610689 2015
Development of a Dissolution Test for Extended-Release Bromopride Pellets with In Vivo-In Vitro Correlation 10.14227/dt220215p24 2015
Preparation and Evaluation of Chitosan Submicroparticles Containing Pilocarpine for Glaucoma Therapy 10.2174/1567201812666150901113240 2015
Topiramate: A Review of Analytical Approaches for the Drug Substance, Its Impurities and Pharmaceutical Formulations 10.1093/chromsci/bmv120 2015
Molecular modeling study of a series of amodiaquine analogues with antimalarial activity 10.1007/s00044-015-1403-z 2015
The oil-resin of the tropical rainforest tree C opaifera langsdorffii reduces cell viability, changes cell morphology and induces cell death in human endometriotic stromal cultures 10.1111/jphp.12479 2015
Probing insulin bioactivity in oral nanoparticles produced by ultrasonication-assisted emulsification/internal gelation 10.2147/ijn.s86313 2015
Rivastigmine hydrogen tartrate polymorphs: solid-state characterisation of transition and polymorphic conversion via milling 10.1016/j.solidstatesciences.2015.09.004 2015
EFAVIRENZ DISSOLUTION ENHANCEMENT II: AQUEOUS CO-SPRAY-DRYING 2015
Development of a Discriminative Intrinsic Dissolution Method for Efavirenz 10.14227/DT210214P31 2014
Assessment of analytical techniques for characterization of crystalline clopidogrel forms in patent applications 10.1590/s1984-82502014000200001 2014
Alginate-based micro and nanoparticles coated with chitosan 10.1166/jcc.2013.1025 2014
Preparation and characterization of polymer/layered silicate pharmaceutical nanobiomaterials using high clay load exfoliation processes 10.1016/j.jiec.2013.12.110 2014
Crystalline forms of nonprotein drugs filed in Brazil from 1995-2005 10.4155/ppa.14.5 2014
Preparation and scale up of extended-release tablets of bromopride 10.1590/s1984-82502014000200008 2014
Intestinal absorption of insulin nanoparticles: contribution of M cells 10.1016/j.nano.2014.02.014 2014
In vitro and in vivo analysis of the antithrombotic and toxicological profile of new antiplatelets N-acylhydrazone derivatives and development of nanosystems 10.1016/j.thromres.2014.05.009 2014
Exploring N-Acylhydrazone Derivatives Against Clinical Resistant Bacterial Strains 10.1007/s00284-014-0591-y 2014
Titanium Dioxide-Montmorillonite Nanocomposite as Photoprotective Agent Against Ultraviolet B Radiation-Induced Mutagenesis in Saccharomyces cerevisiae : A Potential Candidate for Safer Sunscreens 10.1002/jps.24057 2014
Therapeutic Nanosystems for Oral Administration of Insulin 10.2174/1389201015666140915150826 2014
Development of new Babassu Oil Lipidic Nanostructured Systems; Potential Alternative for Benign Prostatic Hyperplasia Therapy 10.2174/1573413710666140806005930 2014
Acaricidal properties of the formulations based on essential oils from Cymbopogon winterianus and Syzygium aromaticum plants 10.1007/s00436-014-4121-4 2014
Segregated Delivery of Rifampicin and Isoniazid from Fixed Dose Combination Bilayer Tablets for the Treatment of Tuberculosis 2014
Efavirenz dissolution enhancement I: co-micronization 10.3390/pharmaceutics5010001 2013
Nanoemulsion containing dapsone for topical administration: a study of in vitro release and epidermal permeation 10.2147/IJN.S39383 2013
Poly ε-caprolactone nanoparticles loaded with Uncaria tomentosa extract: preparation, characterization, and optimization using the Box–Behnken design 10.2147/IJN.S38491 2013
Development and Validation of a Discriminative Dissolution Test for Betamethasone Sodium Phosphate and Betamethasone Dipropionate Intramuscular Injectable Suspension 10.1208/s12249-012-9920-2 2013
Structural model of haptoglobin and its complex with the anticoagulant ecotin variants: structure-activity relationship study and analysis of interactions 10.3109/14756366.2013.774389 2013
Characterization of a new TiF4 and ß-cyclodextrin inclusion complex and its in vitro evaluation on inhibiting enamel demineralization 10.1016/j.archoralbio.2012.11.001 2013
Nanostructured systems containing babassu (Orbignya speciosa) oil as a potential alternative therapy for benign prostatic hyperplasia 10.2147/IJN.S47731 2013
Human thromboxane synthase: comparative modeling and docking evaluation with the competitive inhibitors Dazoxiben and Ozagrel 10.3109/14756366.2013.817403 2013
Development of a Doxazosin and Finasteride Transdermal System for Combination Therapy of Benign Prostatic Hyperplasia 10.1002/jps.23715 2013
In Vitro-In Vivo Correlation of Efavirenz Tablets Using GastroPlus® 10.1208/s12249-013-0016-4 2013
Hologram quantitative structure?activity relationship and comparative molecular field analysis studies within a series of tricyclic phthalimide HIV-1 integrase inhibitors 10.2147/DDDT.S47057 2013
Effect of a sugar-free pediatric antibiotic on primary tooth enamel hardness when exposed to different sucrose exposure conditions in situ 10.1007/s00784-013-1108-y 2013
Development of a high performance liquid chromatography method for quantification of isomers β-caryophyllene and α-humulene in copaiba oleoresin using the Box-Behnken Design 10.1016/j.jchromb.2013.09.024 2013
Molecular Docking Studies of Marine Diterpenes as Inhibitors of Wild-Type and Mutants HIV-1 Reverse Transcriptase 10.3390/md11114127 2013
Desenvolvimento e validação de método analítico por CLAE para a quantificação simultânea de dipropionato de betametasona e fosfato sódico de betametasona em suspensão injetável 10.1590/s0100-40422012000300027 2012
Searching for new antileishmanial lead drug candidates: Synthesis, biological and theoretical evaluations of promising thieno[2,3-b] pyridine derivatives 10.5897/JMA11.109 2012
Influence of the relative composition of trace elements and vitamins in physicochemical stability of total parenteral nutrition formulations for neonatal use 10.1186/1475-2891-11-26 2012
Application of 4D-QSAR Studies of a Series of Raloxifene Analogs and Design of Potential Selective Estrogen Receptor Modulators 10.3390/molecules17067415 2012
Residue-Ligand Interaction Energy (ReLIE) on a Receptor-Dependent 3D-QSAR Analysis of S- and NH-DABOs as Non-Nucleoside Reverse Transcriptase Inhibitors 10.3390/molecules17077666 2012
Sulphonamide and sulphonyl-hydrazone cyclic imide derivatives: Antinociceptive activity, molecular modeling and In Silico ADMET screening 10.1007/s12272-012-1002-1 2012
Preparation and characterization of polysaccharide-based nanoparticles with anticoagulant activity 10.2147/IJN.S31632 2012
Rational use of antioxidants in solid oral pharmaceutical preparations 10.1590/S1984-82502012000300007 2012
Hologram QSAR Models of 4-[(Diethylamino)methyl]-phenol Inhibitors of Acetyl/Butyrylcholinesterase Enzymes as Potential Anti-Alzheimer Agents 10.3390/molecules17089529 2012
Molecular Modeling Studies of the Structural, Electronic and UV Absorption Properties of Benzophenone Derivatives 10.1021/jp306130y 2012
Influence of the Efavirenz Micronization on Tableting and Dissolution 10.3390/pharmaceutics4030430 2012
Development and characterization of a new oral dapsone nanoemulsion system: permeability and in silico bioavailability studies 10.2147/IJN.S36479 2012
Microbiological dental diseases: still waiting for advances in treatment 2012
Identification of Nor-?-Lapachone Derivatives as Potential Antibacterial Compounds against Enterococcus faecalis Clinical Strain 10.1007/s00284-010-9763-6 2011
Preparation and Evaluation of a New Nano Pharmaceutical Excipients and Drug Delivery System Based in Polyvinylpyrrolidone and Silicate 2011
Looking at the proteases from a simple perspective 10.1002/jmr.1091 2011
Effects of a nanocomposite containing Orbignya speciosa lipophilic extract on Benign Prostatic Hyperplasia 10.1016/j.jep.2011.03.003 2011
Bone Remodeling, Biomaterials And Technological Applications: Revisiting Basic Concepts 10.4236/jbnb.2011.23039 2011
Preparation and evaluation of lidocaine hydrochloride in cyclodextrin inclusion complexes for development of stable gel in association with chlorhexidine gluconate for urogenital use 10.2147/IJN.S20409 2011
Chemical stability study of vitamins thiamine, riboflavin, pyridoxine and ascorbic acid in parenteral nutrition for neonatal use 10.1186/1475-2891-10-47 2011
The study of vancomycin use and its adverse reactions associated to patients of a brazilian university hospital 10.1186/1756-0500-4-236 2011
Comparative Analysis of Viperidae Venoms Antibacterial Profile: a Short Communication for Proteomics 10.1093/ecam/nen052 2011
Preparation and evaluation of polymer-clay nanocomposite as an adjuvant in pharmaceutical formulas of tablets containing drugs with low water-solubility 2011
Preparation and evaluation of antimicrobial activity of nanosystems for the control of oral pathogens Streptococcus mutans and Candida albicans 10.2147/IJN.S25667 2011
Preparação de argila modificada com cloreto de cetilpiridíneo e avaliação da interação desta com o PVC 10.1590/S0104-14282010005000031 2010
Oral sustained release nystatin tablets for the treatment of oral candidiasis: formulation development and validation of UV spectrophotometric analytical methodology for content determination 10.3109/03639040903384729 2010
Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases 2010
Erosive effect of an antihistamine liquid formulation on bovine teeth: influence of exposure time 2010
Polysaccharide Based Nanoparticles Development and Charcaterization 2010
Estudo do processo de intercalação via solução PVP-bentonita: a avaliação da influência do tempo reacional, da proporção de polímero-argila e da massa molar média 10.1590/S0104-14282010005000047 2010
Development of methodologies for dimethylaminoethanol glycolate assay in association with sunscreens in dermocosmetic formulation 10.1590/S1984-82502010000400012 2010
Syntesis, antichagasic in vitro evaluation, cytotoxicity assays, molecular modeling and SQR/HQSAR studies of a 2-phenyl-3-(1-phenyl-1H-pyrazol-4-yl)-acrylic acid benzylidene-carbohydrazide series 2009
Current practices on the use of sildenafil citrate for pulmonary arterial hypertension in Brazilian hospitals 10.1186/1756-0500-2-30 2009
Bioequivalence studies and sugar-based excipientes effects on the properties of new generic ketoconazole tablets formulations and stability evaluation by using direct compression method 2009
Antiophidian sera sterility control: topics in perspective 10.1590/s1984-82502009000300004 2009
Influence of the calcium concentration in the presence of organic phosphorus on the physicochemical compatibility and stability of all-in-one admixtures for neonatal use 10.1186/1475-2891-8-51 2009
Preparation of Modified Montmorillonite with Benzethonium and Benzalkonium Chloride for Nanocomposites Preparation. 2009
Inclusion of the Sunscreen Octyl Methoxycinnamate in the beta-Cyclodextrin and Inclusion Complex Purification Assessment by NMR H-1 2009
SAR of a series of anti-HSV-1 acridone derivatives, and a rational acridone-based design of a new anti-HSV-1 3H-benzo[b]pyrazolo[3,4-h]-1,6-naphthyridine series 10.1016/j.bmc.2007.09.032 2008
Avaliação da adequação de industrias de medicamentos fitoterápicos e oficinais do estado do Rio de Janeiro 10.1590/s1413-81232008000700025 2008
Just Working with the Cellular Machine. A High School Game for Teaching Molecular Biology 10.1002/bmb.20164 2008
Speciation of antimony (III) and antimony (V) using hydride generation for meglumine antimoniate pharmaceutical formulations quality control 10.1590/s0074-02762008000200002 2008
Preparation and Evaluation of Inclusion Complexes of Commercial Sunscreens in Cyclodextrins and Montmorillonites: Performance and Substantivity Studies 10.1080/03639040701831769 2008
DNA methylation: A promising target for the twenty-first century 10.1517/14728222.12.8.1035 2008
Indicadores para o controle de processo na manipulação de cápsulas em farmácia 10.1590/S0102-311X1998000400030 2008
Comparative Analysis of Viperidae Venoms Antibacterial 2008
Preparação e avaliação reacional de nanocompósitos de PVP K-30 - Montimorilonita (natural e organicamente modificada) por difração de raio X 2008
Antibacterial profile against drug-resistant Staphylococcus epidermidis clinical strain and structure?activity relationship studies of 1H-pyrazolo[3,4-b]pyridine and thieno[2,3-b]pyridine derivatives 10.1016/j.bmc.2008.07.035 2008
Avaliação de derivados poliméricos intercalados em montmorilonita organofílica na preparação de novos materiais de uso farmacêutico 10.1590/s0104-14282008000300007 2008
Avaliação de bentonita sódica purificada e bentonita sódica intercalada como promotores de dissolução de clorpropamida em comprimidos preparados por granulação úmida e compressão direta 2008
The preparation and evaluation of sodium and alkylammonium montimorilonite and polysaccharides nanocomposites as sustained release excipients 10.1080/03602550802497727 2008
Identification of a Potential Lead Structure for Designing New Antimicrobials to Treat Infections Caused by Staphylococcus epidermidis-Resistant Strains 10.1007/s00284-008-9234-5 2008
Synthesis, in vitro evaluation, and SAR studies of a potential antichagasic 1H-pyrazolo[3,4-b]pyridine series 10.1016/j.bmc.2006.09.067 2007
HIV-1 Reverse Transcriptase: A Therapeutical Target in the Spotlight 10.2174/092986706775476089 2006
Development and validation of a HPLC-UV method for the determination of didanosine tablets 10.1016/j.jpba.2005.02.004 2005
Snake Venom: Any Clue for Antibiotics and CAM? 10.1093/ecam/neh063 2005
Evaluation of delamination process of bentonite with different molecules for drug delivery systems 2005
Evaluation of sodium bentonite-based systems as dissolution ehancers for wet granulated and direct compressed tablets 2005
O Desenvolvimento de Formulações e a Indústria. 2005
Bioinformática na Era Pós-Genômica: métodos de dinâmica. 2005
Desenvolvimento e Validação de Método Analítico. 2005
Solving an Ethical Issue Involved in Experimentation with Animals in a Brazilian Teaching Laboratory Biochemistry and Molecular Biology Education 10.1002/bmb.2004.494032060404 2004
Role of the Undergraduate Student Research Assistant in the New Millennium 10.1187/cbe.04-02-0032 2004
Evaluation of new polysaccharides networks for extended-release purposes: mesquite seed gum (msg), xanthan gum and chitosan. 356342 2003
Development of profitable procedure for extraction of 2-H-1-benzopiran2-one, coumarin from Mikania glomerata 11247531 2001
Evaluation of a galactomanann extracted from prosopis juliflora DC as a new excipient for a pharmaceutical solid dosage forms II 2001
Evaluation of Galactomanann extracted from prosopis juliflora DC as a new excipient for pharmaceutical solid dosage forms 1999
Development of a new rutin and ascorbic acid high dosage tablet formulation 1999
Preliminary Studies Of The Chemical Composition And Antimicrobial Activity Of Mikania Glomerata Sprengel 23106 1998
A galactomannan from the seeds of prosopis juliflora DC: Studies of a new sustained release matrix 1998
Asymmetric Friedel-Crafts Reaction: Studies Towards The Enantiosse Letive Synthesis Of An Etodalac Analogue 1997
Isolation And Identification Of Kaurenoic Acid Derivatives From Mikania Glomerata Sprengel 1997
Preparcao de Membranas de Quitosano e Quitosano e Sulfadiazina de Prata. Uma Promissora Terapia Para Prevencao da Sepsia e Tratamento Depacientes Queimados 1996
Asymmetric Friedel - Crafts Reaction: An Application to the Synthesis of an Etodolac Analogue 10.1080/00397919608003781 1996
The synthesis and analgesic properties of new spiroisochromanyl acid derivatives synthesized from natural safrole 10.1002/jhet.5570320348 1995
Synthesis Of New Analogues Of Antiinflamatory Agents From Safrole 1991
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
IMPRESSÃO 3D SEMISSÓLIDA NA FRONTEIRA DA SAÚDE: UMA REVISÃO DE EXCIPIENTES PARA FORMULAÇÕES PALATÁVEIS E PERSONALIZADAS PARA A TUBERCULOSE INFANTIL 2022
Evaluation of Wound Healing Activity of Euterpe edulis 2022
NANOCRYSTALLIZATION OF NAT22 CHALCONE FOR ORAL TREATMENT OF CUTANEOUS LEISHMANIASIS 2022
Desenvolvimento e Implementação de uma Interface para Sistema de Apoio à Decisão na Área Farmacêutica 2020
Avaliação da Segurança de Agroquímicos Utilizando Métodos in silico 2020
DESENVOLVIMENTO, CARACTERIZAÇÃO E AVALIAÇÃO DO PERFIL ANTIHEMOSTÁTICO E TOXICOLÓGICO DE NANOPARTÍCULAS DE RIVAROXABANA PARA O TRATAMENTO DE DOENÇAS TROMBÓTICAS 2019
SYNTHESIS AND ANTIMALARIAL ACTIVITY OF NEW FLUOROAMODIAQUINE ANALOGUES 2018
Efeito de soluções fluoretadas nanocomplexadas na inibição da desmineralização do esmalte por meio de biofilme cariogênico multiespécie 2018
DEVELOPMENT AND CHARACTERIZATION OF MESOPOROUS SILICA NANOPARTICLES (MSN) FOR DENTAL CARIES PREVETION 2018
Critical powder material properties and their impact on the screw feeding quality attributes of continuous processing lines. 2015
Efeito preventivo de cárie de nanocomplexos à base de ciclodextrinas e TiF4 em diferentes tempos de complexação 2014
Potencial leishmnicida de derivados de tiouréias 2013
In vitro effects of nanocomposite containing Copaifera langsdorffii oleoresin on stromal cells of eutopoc endometrium and endometriotic lesions 2013
DEVELOPMENT OF NEW NANOEMULSIONS OF DAPSONE FOR TOPIC TREATMENT OF LEPROSY 2011
Preparation and evaluation of nanostructured polymeric materials as vectorized systems of babassu oil 2011
Preparation and Evaluation of New Fluoruorinated Derivatives for the Prevention of Caries 2009
Desenvolvimento de Novos Derivados de Tetrafluoreto de Titânio na Busca de Novos Agentes para Prevenção de Cárie 2009
Developmente of Alternative Production Processes of New Theraputic Nanosystems of the Sistemic Cancer 2009
Estudos de Alternativas para a Obtenção de Novos Nanosistemas Terapêuticos para o Combate de Neoplasias Sistêmicas 2009
Patent Applications of Clopidogrel Salts Polymorphic Forms: Evaluation of Analytical Techniques and its Importance for Patent Exam in Brazil 2009
Obtainment and Characterization of Nanocomposites for Pharmaceutical Applications 2009
Desenvolvimento e caracterização de nanopartículas de condroítina-quitosana contendo antimoniato de meglumina. 2009
Production and characterization of chondroitina-quitosan nanoparticles containing meglumine antimonate. 2009
Preparation and evaluation of new prolonged release pharmaceutical formulations of acyclovir and dapsone nanocomposites. 2009
Preparação e avaliação de novos nanosistemas terapêuticos biologicamente ativos de aciclovir e estudos de sua utilização. 2009
Preparação e avaliação de novas formulações farmacêuticas de liberação prolongada de nanocompósitos de aciclovir e dapsona. 2009
Development of new microemulsions of dapsone for topic treatment of leprosy. 2009
Preparação e Avaliação de Sistemas de Liberação de Dapsona 2009
Preparation and evaluation of dapsone microemulsion systems. 2009
Preparação e avaliação de novos nanosistemas a base de silicatos lamelares para a terapia de neoplasias sistêmicas. 2009
Estudos de relação estrutura-atividade e preparação de toxicidade "in silico" de chalconas com atividade antitumoral. 2009
Efeito da diluição de xaropes infantis em seus valores de pH e acidez titulável. 2009
Preparação e Avaliação de Sistemas Microemulsionados Ativos da Dapsona. 2009
FBPol 2008 - Preparation of modified montmorillonite with surfactants like benzalconium, benzethonium or cetylpyridinium chloride to a possible application in processing of PVC 2008
Preparation and evaluation of new combined dissolution enhancers for class II drug formulation 2008
Influência do tempo de exposição no efeito erosivo de medicamentos líquidos 2008
Efeitos da diluição no potencial erosivo de medicamentos líquidos infantis 2008
Efeito remineralizador in vivo do tetrafluoreto de titânio a 4% em associação ao dentifrício fluoretado 2008
Polychar 15. Reactional evaluation of formation of PVP - organophilic montmorillonite nanocomposites. 2007
Polychar 15. Evaluation of solvente effect in preparation of PEG - organophilic montmorillonite nanocomposites by X-ray diffraction and low field nuclear magnetic resonance. 2007
6th CIFARP. Phytochemical and pharmacological evaluation of malpighiacea species of used in Rio de Janeiro. 2007
6th CIFARP.Phytochemical evaluation of Byrsonima sericea and use as permeation enhancer in cosmetic formulations. 2007
6th CIFARP. Development of oral nystatin pills for oral candidiasis treatment 2007
6th CIFARP. Molecular modeling studies of a potential antichagasic N´-benzylidene hydrazide. 2007
Study of sodium mantmorillonite modification with benzethonium chloride and evaluation like pharmaceutical excipient. 2007
Preparation of PVP - montmorillonite nanocomposites and its evaluation as pharmaceutical excipient. 2007
18o CIORJ - Estudo do potencial de frutas na prevenção de cárie em odontopediatria. 2007
RioPharma 5o Congresso de Ciências Farmacêuticas. Desenvolvimento de Comprimidos Bucais de Nistatina para o Tratamento da Candidíase Oral. 2007
9o CBPol. Avaliação do efeito do solvente na preparação de nanocompósitos de PVC e montmorilonita organofílica por difração de raios X e ressonância magnética nuclear de baixo campo. 2007
9o CBPol. Preparação e avaliação reacional de nanocompósitos de PVP - montmorilonita (natural e organicamente modificada). 2007
Riopharma 5o Congresso de Ciências Farmacêuticas. O Uso de Sildenafil no Tratamento da Hipertensão Pulmonar. 2007
Intercalation Process Studies for Preparation of New Nanocomposites PVPK-30- Bentonite (natural and organophilic) 2007
20o Congresso Brasileiro de Cosmetologia - Estudo de cedência do filtro solar p-Metoxicinamato de Octila incluso em sistemas de liberação 2006
Macro 2006. 41st International Symposium on Macromolecules. Preparation, characterization and evaluation of organophilic montmorillonite nanocomposites as pharmaceutical excipients 2006
Macro 2006. 41st International Symposium on Macromolecules. Evaluation of organo-modified bentonite as a tortuosity controller of matrix drug delivery systems 2006
Synthesis and characterization of macromolecular prodrug based on acrylic acid and 5-aminosalicylic acid 2006
Congresso Mundial de Farmácia e Ciências Farmacêuticas, 66º Congresso Internacional da FIP. Estudos Fitoquímicos e Farmacológicos em espécies da Família Malpighiaceae utilizadas no Rio e Janeiro 2006
Farmapolis 13a edição. Síntese e caracterização de nanocompósitos derivados de montmorilonita visando sua utilização como novas matrizes mistas para a liberação controlada. 2005
Farmapolis 13a edição. Desenvolvimento de uma nova classificação farmacotécnica de riscos em desvios da qualidade de medicamentos 2005
Farmapolis 13a edição. Preparação e avaliação de novos compósitos poliméricos para liberação prolongada de fármacos - uso de PVP e montmorilonita organofílica 2005
Farmapolis 13a edição. Avaliação de nanocompósitos polímero-argila na liberação matricial de dapsona 2005
IV Bienal de Pesquisa. Desenvolvimento e validação da metodologia de determinação dos comprimidos de didanosina por CLAE 2004
II Simpósio Brasileiro de Vigilância Sanitária / I Simpósio Pan-Americano de Vigilância Sanitária. Validação de método analítico para determinação de Sb III na presença de Sb V por geração de hidreto em espectroscopia de emissão atômica usando plasma indutivamente acoplado (HG-ICP-AES) de soluções injetáveis de antimoniato de meglumina 2004
Rio Pharma 3o congresso de ciências farmacêuticas do Rio de Janeiro. Farmacoepidemiologia - Avaliação do uso de montimorilonato de sódio na preparação de novos nanosistemas fotoprotetores 2003
Rio Pharma 3o congresso de ciências farmacêuticas do Rio de Janeiro. TecnologiaFarmacêutica e de Cosméticos - Avaliação do uso de nanocompósitos montimorilonita-polissacarídeos como novas matrizes de liberação prolongada 2003
Rio Pharma 3o congresso de ciências farmacêuticas do Rio de Janeiro. Tecnologia Farmacêutica e de Cosméticos - Estudo da utilização de incrementadores de dissolução para compressão direta: enfoque no desenvolvimento de medicamentos genéricos 2003
Rio Pharma 3º Congresso de ciências farmacêuticas do Rio de Janeiro. Tecnologia Farmacêutica e de cosméticos- Uso de incrementadores de dissolução em comprimidos preparados por granulação úmida 2003
VII Pharmatech. IV ENECQ. Evaluation of the use of sodium montimorilonite in the preparation of new photoprotectors nanosystems 2003
VII Pharmatech. IV ENECQ. Use of dissolution enhancers in granulation wet chemistry 2003
VII Pharmatech. IV ENECQ. Study of dissolution for direct compression: focus in the development of generic drugs formulations 2003
VII Pharmatech. IV ENECQ. Evaluation of montimorilonite polysaccharides nanocomposites use as new matrices of sustained release 2003
Rio Pharma 2o congresso de ciências farmacêuticas do Rio de Janeiro. Avaliação de preparações anti-solares contendo quitosano 2001
Rio Pharma 2o congresso de ciências farmacêuticas do Rio de Janeiro; Avaliação da Irritabilidade dérmica e Ocular de Filtros Solares Inclusos em ciclodextrinas 2001
VI Pharmatech Substantivity evaluation of the sunscreen octyl methoxycinnamate in diferents systems: liposomes, lipospheres, b-cyclodextrin and chitosan complex 2001
Un nuovo eccipiente di natura polisaccaridica ricavato dai semi di prosopis juliflora DC 1999
Evaluation of a new galactomannan as a matrix for sustained drug delivery 1999
Evaluation of Mesquite seed Gum (MSG) as hydrophilic matrix for extended release purposes 1999
Study of preparation methodology and validation of high dosage tablets 1999
Estudos preliminares visando a obtenção de cumarina a partir de Mikania glomerata sprengel. Desenvolvimento de processos extrataivos economicamente viáveis 1997
Enantioselective synthesis of an etodolac analogue: a Friedel-crafts like asymetric reaction 1996
Estudo da atividade antimicrobiana de Mikania glomerata sprengel 1996
Contribuição para o estudo fitoquímico de Mikania glomerata sprendel 1996
Avaliação de novos auxiliares de quiralidade derivados do 1-(S)-(-)-b-pineno: sintese enantiosseletiva de um analogo do etodolac 1995
Studies towards the enantioselective synthesis of etodolac 1994
Estudos visando a sintese enantiosseletiva do acido {[1,3,4,9,tetraidropirano]3,4,b-indol}-acetico, etodolac 1994
Síntese de novos agentes NSAI a partir do safrol 1993
The synthesis of new analogues of antiinflamatory agents from safrole 1991
Estudos sobre a utilização em síntese da 2-metil-5,6-metilenodioxi indanona 1990
Síntese de um novo analogo do sulindac a partir do safrol 1989
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