Raoni Schroeder Borges Gonçalves

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências Matemáticas e da Natureza

Unidade:

Instituto de Química

Departamento:

Departamento de Química Orgânica/IQ

ORCID:

https://orcid.org/0000-0003-1305-9434


Formação:

  • Bayer Research Center

    | Pós-Doutorado | 2018 - 2019

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2013 - 2014

  • Universidade Federal do Rio de Janeiro

    Química | Doutorado | 2009 - 2013

  • Universidade Federal do Rio de Janeiro

    Química Com Atribuições Tecnológicas | Graduação | 2004 - 2008
Laboratórios:
Nuvens de Palavras:
Artigos:

(87.50% artigos com DOI)

Titulo DOI Ano
Editorial: Nucleosides, nucleotides and nucleic acids: chemistry and biology 10.3389/fchem.2024.1401510 2024
Cyclodextrin-encapsulated new drug with promising anti-Trypanosoma cruzi activity 10.1007/s10973-023-12403-x 2023
Novel Organic Salts Based on Mefloquine: Synthesis, Solubility, Permeability, and In Vitro Activity against Mycobacterium tuberculosis 10.3390/molecules27165167 2022
Antileishmanial Activity of 4,8-Dimethoxynaphthalenyl Chalcones on Leishmania amazonensis 10.3390/antibiotics11101402 2022
Mefloquine synergism with anti-tuberculosis drugs and correlation to membrane effects: biologic, spectroscopic and molecular dynamics simulations studies 10.1016/j.bioorg.2021.104786 2021
Crystal structures, DFT calculations and Hirshfeld surface analysis of two (E)-3-(aryl)-1-(naphthalen-1-yl)prop-2-en-1-one chalcone derivatives, potential Mycobacterium tuberculosis Enoyl ACP reductase (InhA) inhibitors and optical materials: conformational differences within the prop-2-en-1-one unit 10.1016/j.molstruc.2021.131091 2021
Studies on the laccases catalyzed oxidation of norbelladine like acetamides 10.1016/j.mcat.2020.110788 2020
Enzyme Immobilization in Covalent Organic Frameworks: Strategies and Applications in Biocatalysis 10.1002/cplu.202000549 2020
Hexafluoroisopropanol (HFIP, CAS No 920-66-1) 10.21577/1984-6835.20200104 2020
Enzyme-Decorated Covalent Organic Frameworks as Nanoporous Platforms for Heterogeneous Biocatalysis 10.1002/chem.201903807 2019
N-Difluoromethyl-triazole as a constrained scaffold in peptidomimetics 10.1039/C7CC01298E 2017
Further study of oxazolidines derived from mefloquine and arenealdehydes: diastereoisomers and polymorphs 10.1515/zkri-2015-1858 2016
Heterogeneous Catalysis by Covalent Organic Frameworks (COF): Pd(OAc) 2 @COF-300 in Cross-Coupling Reactions 10.1002/cctc.201500926 2016
Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection 10.1016/j.ijantimicag.2016.04.029 2016
Mefloquine and its oxazolidine derivative compound are active against drug-resistant Mycobacterium tuberculosis strains and in a murine model of tuberculosis infection 10.1016/j.ijantimicag.2016.04.029 2016
An Environmentally Friendly, Scalable and Highly Efficient Synthesis of (S,S)-Ethambutol, a First Line Drug against Tuberculosis 10.2174/1570178612666150521235908 2015
Mefloquine-Oxazolidine Derivatives: A New Class of Anticancer Agents 10.1111/cbdd.12210 2014
Crystal structures of three 4-[3-(XC6H4)-hexahydro[1,3] oxazolo[3,4-a]pyridin-1-yl]-2,8-bis(trifluoromethyl)quinolines (X = 3-MeO, 4-MeO and 4-HO) 10.1524/zkri.2013.1618 2013
A one-pot synthesis of 3-trifluoromethyl-2-isoxazolines from trifluoromethyl aldoxime 10.3762/bjoc.9.275 2013
Crystal structures of mefloquine-oxazolidine derivatives, 4-[3-(halophenyl)hexahydro[1,3]oxazolo[3,4-a]pyridin-1-yl]- 2,8-bis(trifluoromethyl)quinolines 10.1524/zkri.2013.1691 2013
Mefloquineâ¿¿oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113 10.1016/j.bmc.2011.11.006 2012
In vitro anti-mycobacterial activity of (E)-N´-(monosubstituted-benzylidene) isonicotinohydrazide derivatives against isoniazid-resistant strains 10.4081/idr.2012.e13 2012
Simultaneous Analysis of Isoniazid and Its Impurities by CZE 10.1007/s10337-012-2308-3 2012
Synthesis and Antitubercular Evaluation of -Arylpyrazine and -Alkyl-diylpyrazine-2-carboxamide Derivatives 10.1002/jhet.921 2012
Mefloquine-oxazolidine derivatives, derived from mefloquine and arenecarbaldehydes: In vitro activity including against the multidrug-resistant tuberculosis strain T113 10.1016/j.bmc.2011.11.006 2012
Simple Methodology for the Preparation of Amino Alcohols from Amino Acid Esters Using NaBH 10.1080/00397911.2010.481747 2011
2-{1-[2,8-Bis(trifluoromethyl)quinolin-4-yl]-3,5,6,7,8,8a-hexahydro-1 -1,3-oxazolo[3,4- ]pyridin-3-yl}phenol 10.1107/S1600536811022379 2011
tert-Butyl 2-{[2,8-bis(trifluoromethyl)quinolin-4-yl](hydroxy)methyl}piperidine-1-carboxylate 10.1107/s1600536811047726 2011
Benzyl 2-{[2,8-bis(trifluoromethyl)quinolin-4-yl](hydroxy)methyl}piperidine-1-carboxylate 10.1107/s1600536811047738 2011
Structures of 4-{3-(X-phenyl)perhydro-1,3-oxazolo[3,4-a]pyridin-1-yl}-2,8-bis(trifluoromethyl)quinolines (X = H, 2-O 10.1524/zkri.2011.1426 2011
( 10.1107/s1600536811038128 2011
Recent Developments in Pleuromutilin Derivatives: A Promising Class Against Bacterial Respiratory Disease 10.2174/157339810791171287 2010
2-Bromopyridine-3-carboxylic acid 10.1107/S1600536810003314 2010
Synthesis and Antitubercular Activity of Heteroaromatic Isonicotinoyl and 7-Chloro-4-Quinolinyl Hydrazone Derivatives 10.1100/tsw.2010.124 2010
Synthesis and antitubercular activity of new mefloquine-oxazolidine derivatives 10.1016/j.ejmech.2010.09.024 2010
Synthesis and Antitubercular Activity of Heteroaromatic Isonicotinoyl and 7-Chloro-4-Quinolinyl Hydrazone Derivatives 10.1100/tsw.2010.124 2010
Synthesis and antitubercular activity of new mefloquine-oxazolidine derivatives 10.1016/j.ejmech.2010.09.024 2010
Produtos Naturais Inibidores da Transcriptase Reversa, Uma Importante Enzima do Ciclo de Replicação do Vírus HIV 2009
Synthesis and Antitubercular Evaluation of N'-[(E)-(hydroxy, methoxy and ethoxy-substituted-phenyl) Methylidene]isonicotinohydrazide Derivatives 10.2174/157018008783928472 2008
Synthesis and Biological Evaluation of N-(Alkyl)-2-Thiophen-2-Ylacetamides Series As A New Class of Antitubercular Agents 10.2174/157018008784083965 2008
(+)-Calanolida A, um promissor produto natural no combate a replicação do vírus HIV e da bactéria Mycobacterium tuberculosis. 2008
Lamivudine, an important drug in aids treatment 10.1080/17415990802183876 2008
Synthesis and Biological Evaluation of N,N⿲-di(thiopheneacetyl)diamines Series as Antitubercular Agents 10.1080/10426500802049803 2008
Tuberculose infantil: tratamento e problemas relacionados 2007
Evaluation of anti-tubercular activity of nicotinic and isoniazid analogues 2007
Produtos Natrurais em fase avançada de testes clínicos no tratamento contra o câncer 2007
Synthesis and biological evaluation of N-(aryl)-2-thiophen-2-ylacetamides series as a new class of antitubercular agents 10.1016/j.bmcl.2007.09.096 2007
Triterpenos como Inibidores de Fusão: Uma Nova Estratégia no Combate ao Vírus HIV 2006
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
A APLICAÇÃO DO TEMA GERADOR FÁRMACOS UTILIZADOS NO TRATAMENTO DE TUBERCULOSE PARA ENSINAR QUÍMICA ORGÂNICA AOS ALUNOS DO ENSINO MÉDIO 2022
ELABORAÇÃO DE UMA SEQUÊNCIA DIDÁTICA UTILIZANDO-SE O TEMA GERADOR FÁRMACOS PARA O ENSINO DE QUÍMICA ORGÂNICA NO ENSINO MÉDIO 2022
Objetos Inteligentes e Química Medicinal como Temática para o Ensino de Química Orgânica no Ensino Médio 2021
DESENVOLVIMENTO DE UM MATERIAL DIDÁTICO COM BASE NO TRATAMENTO DE PRIMEIRA ESCOLHA DA TUBERCULOSE PARA O ENSINO DE QUÍMICA ORGÂNICA PARA ALUNOS DO ENSINO MÉDIO 2021
Development of new potential Mycobacterium tuberculosis enoyl-ACP reductase inhibitors 2019
Rutênio Suportdo na Rede Orgânica Covalente RIO-55: Uma Nova Plataforma para Fotocatálise Heterogênea 2019
DESIGN OF NEW POTENTIAL MYCOBACTERIUM TUBERCULOSIS ENOYL-ACP REDUCTASE (INHA) INHIBITORS BY MOLECULAR MODELING 2017
DESENVOLVIMENTO DE NOVOS INIBIDORES DA ENZIMA ENOIL-ACP REDUTASE DO MYCOBACTERIUM TUBERCULOSIS 2017
Redes orgânicas covalentes como uma nova plataforma para criação de biocatalizadores heterogêneos nanoestruturados 2017
REDES ORGÂNICAS COVALENTES COMO UMA NOVA PLATAFORMA PARA A IMOBILIZAÇÃO DE ENZIMAS 2016
Cross-​coupling reactions catalyzed by palladium caged into covalent organic framework nanopores. 2014
Design and Synthesis of Hybrid Molecules with Potential Antimalarial Activity 2012
Design and Synthesis of Hybrid Molecules with Potential Antimalarial Activity 2012
Design and Synthesis of Hybrid Molecules with Potential Antimalarial Activity 2012
Design and Synthesis of Hybrid Molecules with Potential Antimalarial Activity 2012
Método alternativo para a redução de ésteres de aminoácidos com NaBH4 e metanol em THF 2011
Síntese e avaliação tuberculostática de novos derivados da mefloquina. 2011
Síntese e avaliação de pirazinocarboxiamidas monossubstituídas com potencial atividade contra a tuberculose 2011
Determinação simultânea de isoniazida, suas impurezas de síntese e produtos de degradação por eletroforese capilar de zona 2010
Síntese e avaliação biológica de derivados N,N'-di-(tiofenoacetil)diaminas como uma nova classe de agentes tuberculostáticos. 2009
Sínetese e Avaliação Biologica de Derivados N-(Aril)-2-tiofenil-2-acetamidas como uma nova classe de agentes Tubelculostáticos. 2008
Síntese de Derivados do Carboidrato D-manitol com Potencial Atividade contra a Tuberculose. 2008
Combinação de Fármacos Utilizados no Combate à Malária e à Tuberculose com Fluoroquinolonas. 2008
Synthesis and antimycobacterial evaluation of D-mannitol derivatives. 2008
MÉTODO ALTERNATIVO PARA A REDUÇÃO DE ÉSTERES DE AMINO-ÁCIDOS COM BOROHIDRETO DE SÓDIO. EFICIENTE OBTENÇÃO DE AMINO-ÁLCOOIS QUIRAIS E APLICAÇÃO DESTES PARA A SÍNTESE DO ETAMBUTOL E ANÁLOGOS. 2008
Sintese e Atividade Antimicobacteriana de Derivados do Ácido Isonicotínico 2007
Síntese e Atividade Anti-Micobacteriana de Derivados dos Ácidos Benzóico e Isonicotínico. 2007
Síntese de Derivados N,N'-bis-2-pirazinocarboxiamida. 2007
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