Patricia Dias Fernandes
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Ciências Biomédicas
Departamento:
Diretoria Adjunta de Pós-graduação/ICB
e-mail:
patricia.dias.icbufrj@gmail.com
Linkedin:
Google Scholar:
ORCID:
https://orcid.org/0000-0001-6870-6745
Formação:
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Universidade de São Paulo
| Pós-Doutorado | 2004 - 2005
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Universidade de São Paulo
| Pós-Doutorado | 2003 - 2004
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Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 1992 - 1996
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Universidade Federal do Rio de Janeiro
Química Biológica | Mestrado | 1988 - 1990
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Universidade Federal do Estado do Rio de Janeiro
Ciências Biológicas | Graduação | 1982 - 1987
Laboratórios:
Nuvens de Palavras:
Artigos:
(84.96% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| - N -Alkanoyl-5-Hydroxytryptamines (C n -5HTs) in Coffee: A Review | 10.1080/87559129.2022.2059807 | 2022 |
| Endometriosis: A Disease with Few Direct Treatment Options | 10.3390/molecules27134034 | 2022 |
| Novel Regioisomeric Analogues of Naphthyl-N-Acylhydrazone Derivatives and Their Anti-Inflammatory Effects | 10.3390/ijms232113562 | 2022 |
| Copaiba Oil Resin Exerts an Additive Effect to Babassu Oil on Behavioral Changes in Human Endometriotic Cell Cultures | 10.3390/ ph15111414 | 2022 |
| Tibouchina granulosa Leaves Present Anti-Inflammatory Effect | 10.3390/ ph15121458 | 2022 |
| Phenylbenzohydrazides Obtained from Isatoic Anhydride Present Anti-Inflammatory Activity In Vivo and In Vitro | 10.3390/ biom12121901 | 2022 |
| 2-Arylpropionic Acid Pyrazolamides as Cannabinoid CB2 Receptor Inverse Agonists Endowed with Anti-Inflammatory Properties | 10.3390/ ph15121519 | 2022 |
| Synthesis and Biological Evaluation of Benzo[f]indole-4,9-diones N-Linked to Carbohydrate Chains as New Type of Antitumor Agents | 10.21577/0103-5053.20200202 | 2021 |
| The role of kallikrein-kinin and renin-angiotensin systems in COVID-19 infection | 10.1016/j.peptides.2020.170428 | 2021 |
| Two New βN-Alkanoyl-5-Hydroxytryptamides with Relevant Antinociceptive Activity | 10.3390/biomedicines9050455 | 2021 |
| Novel Single Inhibitor of HDAC6/8 and Dual Inhibitor of PI3K/HDAC6 as Potential Alternative Treatments for Prostate Cancer | 10.3390/ph14050387 | 2021 |
| Characterization of βN-Octadecanoyl-5-hydroxytryptamide Anti-Inflammatory Effect | 10.3390/molecules26123709 | 2021 |
| Benzo[f]indole-4,9-dione Derivatives Effectively Inhibit the Growth of Triple-Negative Breast Cancer | 10.3390/molecules26154414 | 2021 |
| Antinociceptive activity of puberulin and choisyine from ethanol extract of Choisya ternata Kunth var. Sundance | 10.1016/j.biopha.2021.111926 | 2021 |
| New 2-amino-pyridinyl-N-acylhydrazones: Synthesis and identification of their mechanism of anti-inflammatory action | 10.1016/j.biopha.2019.109739 | 2020 |
| Design, Synthesis, and Pharmacological Evaluation of First-in-Class Multitarget N -Acylhydrazone Derivatives as Selective HDAC6/8 and PI3Kα Inhibitors | 10.1002/cmdc.201900716 | 2020 |
| Characterization of the Antinociceptive Activity from Stevia serrata Cav | 10.3390/biomedicines8040079 | 2020 |
| Aristolochia trilobata: Identification of the Anti- Inflammatory and Antinociceptive Effects | 10.3390/biomedicines8050111 | 2020 |
| Pharmacological Evaluation of Artemisia cina Crude CO2 Subcritical Extract after the Removal of Santonin by Means of High Speed Countercurrent Chromatography | 10.3390/molecules25122728 | 2020 |
| Therapeutic Effects of Anti-Inflammatory N-Acylhydrazones in the Resolution of Experimental Colitis | 10.1124/jpet.120.000074 | 2020 |
| Chemistry and Pharmacology of the Kazakh Crataegus Almaatensis Pojark: An Asian Herbal Medicine | 10.3390/antiox8080300 | 2019 |
| Study on the Antinociceptive Activity and Mechanism of Action of Isolated Saponins from Siolmatra brasiliensis (Cogn.) Baill | 10.3390/molecules24244584 | 2019 |
| New βN-octadecanoyl-5-hydroxytryptamide: antinociceptive effect and possible mechanism of action in mice | 10.1038/s41598-018-28355-4 | 2018 |
| Anti-inflammatory, antinociceptive and antioxidant properties of Schinopsis brasiliensis bark | 10.1016/j.jep.2017.11.012 | 2018 |
| Synthesis and pharmacological evaluation of novel isoquinoline N -sulphonylhydrazones designed as ROCK inhibitors | 10.1080/14756366.2018.1490732 | 2018 |
| Characterization of anti-inflammatory effect and possible mechanism of action of | 10.1111/jphp.12712 | 2017 |
| Discovery of naphthyl- N -acylhydrazone p38α MAPK inhibitors with in vivo anti-inflammatory and anti-TNF-α activity | 10.1111/cbdd.13085 | 2017 |
| Development and evaluation of an inhalation chamber for in vivo tests | 10.1590/0001-3765201720160793 | 2017 |
| ROCK inhibition with Fasudil induces beta-catenin nuclear translocation and inhibits cell migration of MDA-MB 231 human breast cancer cells | 10.1038/s41598-017-14216-z | 2017 |
| Isolation of quinoline alkaloids from three Choisya species by high-speed countercurrent chromatography and the determination of their antioxidant capacity | 10.1016/j.bjp.2017.01.003 | 2017 |
| Antinociceptive activity of Cistanche salsa stolons, growing in the Republic of Kazakhstan | 10.1016/j.bjp.2017.05.013 | 2017 |
| Ethnopharmacological Evaluation of Breu Essential Oils from Protium Species Administered by Inhalation | 10.1155/2017/2924171 | 2017 |
| Chemical composition and evaluation of antinociceptive activity of the essential oil of Cav. from Guatemala | 10.1080/14786419.2017.1399376 | 2017 |
| Wound healing properties of Copaifera paupera in diabetic mice | 10.1371/journal.pone.0187380 | 2017 |
| Antinociceptive effect and mechanism of action of isatin, N-methyl isatin and oxopropyl isatin in mice | 10.1016/j.lfs.2016.02.052 | 2016 |
| Discovery of Novel Orally Active Tetrahydro-Naphthyl-N-Acylhydrazones with In Vivo Anti-TNF-α Effect and Remarkable Anti-Inflammatory Properties | 10.1371/journal.pone.0156271 | 2016 |
| Anti-Inflammatory Properties and Chemical Characterization of the Essential Oils of Four Citrus Species | 10.1371/journal.pone.0153643 | 2016 |
| Chemical Constituents of Psychotria nemorosa Gardner and Antinociceptive Activity | 10.21577/0103-5053.20160219 | 2016 |
| Antinociceptive Activity of Zanthoxylum piperitum DC. Essential Oil | 2016 | |
| Membrane cholesterol depletion reduces breast tumor cell migration by a mechanism that involves non-canonical Wnt signaling and IL-10 secretion | 10.1186/s41231-016-0002-4 | 2016 |
| ADME studies and preliminary safety pharmacology of LDT5, a lead compound for the treatment of benign prostatic hyperplasia | 10.1590/1414-431x20165542 | 2016 |
| Quinoline Alkaloids Isolated from Choisya Aztec-Pearl and Their Contribution to the Overall Antinociceptive Activity of This Plant | 10.1371/journal.pone.0164998 | 2016 |
| Anti-Inflammatory Activity of Choisya ternata Kunth Essential Oil, Ternanthranin, and Its Two Synthetic Analogs (Methyl and Propyl N-Methylanthranilates) | 10.1371/journal.pone.0121063 | 2015 |
| Design, synthesis and in vivo evaluation of sodium 2-benzyl-chloromalonates as new central nervous system depressants | 10.1039/c5md00187k | 2015 |
| Central and peripheral antinociceptive activity of 3-(2-oxopropyl)-3-hydroxy-2-oxindoles | 10.1016/j.pbb.2015.05.004 | 2015 |
| Central Antinociceptive and Mechanism of Action of Kunth Leaves Crude Extract, Fractions, and Isolated Compounds | 10.1155/2015/915927 | 2015 |
| LASSBio-1829 Hydrochloride: Development of a New Orally Active N -Acylhydrazone IKK2 Inhibitor with Anti-inflammatory Properties | 10.1002/cmdc.201500266 | 2015 |
| Synthesis of a new class of naphthoquinone glycoconjugates and evaluation of their potential as antitumoral agents | 10.1039/c5ra19192k | 2015 |
| The oil-resin of the tropical rainforest tree C opaifera langsdorffii reduces cell viability, changes cell morphology and induces cell death in human endometriotic stromal cultures | 10.1111/jphp.12479 | 2015 |
| Novel Potent Imidazo[1,2-a]pyridine-N-Glycinyl-Hydrazone Inhibitors of TNF-α Production: In Vitro and In Vivo Studies | 10.1371/journal.pone.0091660 | 2014 |
| Antinociceptive esters of N-methylanthranilic acid: Mechanism of action in heat-mediated pain | 10.1016/j.ejphar.2013.12.042 | 2014 |
| Characterization of the inflammatory response during Ehrlich ascitic tumor development | 10.1016/j.vascn.2014.09.001 | 2014 |
| Anti-inflammatory properties of convolutamydine A and two structural analogues | 10.1016/j.lfs.2014.08.019 | 2014 |
| Wound healing effect of Tibouchina granulosa aqueous extract in diabetic animals | 10.1055/s-0034-1394901 | 2014 |
| Pharmacological characterization of Tibouchina granulosa | 10.1055/s-0034-1394972 | 2014 |
| Pharmacological investigation of Choisya Aztec Pearl | 10.1055/s-0034-1394944 | 2014 |
| Anti-inflammatory effect of Lippia origanoides | 10.1055/s-0034-1394929 | 2014 |
| Evaluation of antinociceptive and/or anti-inflammatory activity of Choisya Aztec Pearl | 10.1055/s-0034-1394900 | 2014 |
| Antinociceptive and anti-inflammatory activities of Elsholtzia ciliata (Thunb.) Hyl. (Lamiaceae) extracts | 10.1055/s-0034-1394646 | 2014 |
| Convolutamydine A and synthetic analogues have antinociceptive properties in mice | 10.1016/j.pbb.2012.09.023 | 2013 |
| Immunobiologic and Antiinflammatory Properties of a Bark Extract from Ampelozizyphus amazonicus Ducke | 10.1155/2013/451679 | 2013 |
| Anti-inflammatory, antioxidant, and antimicrobial activities of Cocos nucifera var. typica | 10.1186/1472-6882-13-107 | 2013 |
| Anti-inflammatory activity of ethanol extract and fractions from Couroupita guianensis Aublet leaves | 10.1016/j.jep.2012.12.053 | 2013 |
| A novel toxic alkaloid from poison hemlock (Conium maculatum L., Apiaceae): Identification, synthesis and antinociceptive activity | 10.1016/j.fct.2011.10.060 | 2012 |
| Antinociceptive effect of the Orbignya speciosa Mart. (Babassu) leaves: Evidence for the involvement of apigenin | 10.1016/j.lfs.2012.06.013 | 2012 |
| Pharmacological mechanisms involved in the antinociceptive effects of dexmedetomidine in mice | 10.1111/j.1472-8206.2012.01068.x | 2012 |
| Anti-nociceptive activity of Pereskia bleo Kunth. (Cactaceae) leaves extracts | 10.1016/j.jep.2012.10.029 | 2012 |
| Characterization of the anti-inflammatory effect from the essential oil of Citrus latifolia | 10.1055/s-0032-1320838 | 2012 |
| The latex obtained from Hancornia speciosa Gomes possesses anti-inflammatory activity | 10.1016/j.jep.2011.03.059 | 2011 |
| Identification of a new antinociceptive alkaloid isopropyl N-methylanthranilate from the essential oil of Choisya ternata Kunth | 10.1016/j.jep.2011.03.035 | 2011 |
| Characterisation of the anti-inflammatory and antinociceptive activities and the mechanism of the action of Lippia gracilis essential oil | 10.1016/j.jep.2011.03.032 | 2011 |
| Effects of a nanocomposite containing Orbignya speciosa lipophilic extract on Benign Prostatic Hyperplasia | 10.1016/j.jep.2011.03.003 | 2011 |
| Characterisation of the anti-inflammatory and antinociceptive activities of the Hyptis pectinata (L.) Poit essential oil | 10.1016/j.jep.2011.01.027 | 2011 |
| The bradykinin B1 receptor antagonist R-954 inhibits Ehrlich tumor growth in rodents | 10.1016/j.peptides.2011.07.023 | 2011 |
| Antinociceptive activity of (¿)-(2S,6S)-(6-ethyl-tetrahydropyran-2-yl)-formic acid on acute pain in mice | 10.1097/FBP.0b013e3283474a1b | 2011 |
| A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis with an antiangiogenic effect in a rat model | 10.1016/j.fertnstert.2009.11.037 | 2010 |
| Antinociceptive activity of fractions from Couroupita guianensis Aubl. leaves | 10.1016/j.jep.2009.10.025 | 2010 |
| Flavones and phenylpropanoids from a sedative extract of Lantana trifolia L. | 10.1016/j.phytochem.2009.10.007 | 2010 |
| Characterization of the antinociceptive and anti-inflammatory activities of fractions obtained from Copaifera multijuga Hayne | 10.1016/j.jep.2010.01.005 | 2010 |
| Platelet-activating factor receptor (PAF-R)-dependent pathways control tumour growth and tumour response to chemotherapy | 10.1186/1471-2407-10-200 | 2010 |
| Structural determination Vitex cymosa Bertero active principle: Diastereoselective synthesis of (±)-trans-4-hydroxy-6-propyl-1-oxocyclohexan-2-one and its antinociceptive activity | 10.1016/j.bioorg.2010.05.001 | 2010 |
| Characterization of the antinociceptive and anti-inflammatory activities from Cocos nucifera L. (Palmae) | 10.1016/j.jep.2009.01.024 | 2009 |
| Antineoplasic activity of Copaifera multijuga oil and fractions against ascitic and solid Ehrlich tumor | 10.1016/j.jep.2008.06.033 | 2008 |
| Production of nitric oxide by airways neutrophils in the initial phase of murine asthma | 10.1016/j.intimp.2006.09.004 | 2007 |
| Antinociceptive activity of Amazonian Copaiba oils | 10.1016/j.jep.2006.08.018 | 2007 |
| Isatins inhibit cyclooxygenase-2 and inducible nitric oxide synthase in a mouse macrophage cell line | 10.1016/j.ejphar.2006.10.057 | 2007 |
| Nitric oxide levels and the severity of juvenile idiopathic arthritis | 10.1007/s00296-007-0321-x | 2007 |
| Cross-regulation of iNOS and COX-2 by its products in murine macrophages under stress conditions | 2007 | |
| Inhibitory effects of Euterpe oleracea Mart. on nitric oxide production and iNOS expression | 10.1016/j.jep.2006.03.010 | 2006 |
| Phagocytosis of apoptotic and necrotic thymocytes is inhibited by PAF-receptor antagonists and affects LPS-induced COX-2 expression in murine macrophages | 10.1016/j.prostaglandins.2006.04.002 | 2006 |
| Antinociceptive action of (±)-cis-(6-ethyl-tetrahydropyran-2-yl)-formic acid in mice | 10.1016/j.ejphar.2006.06.067 | 2006 |
| Evaluation of the antinociceptive properties from Brillantaisia palisotii Lindau stems extracts | 10.1016/j.jep.2005.06.033 | 2005 |
| Investigation of anti-inflammatory and antinociceptive activities of | 10.1016/j.jep.2005.02.040 | 2005 |
| Involvement of PAF receptor in the phagocytosis of apoptotic and necrotic cells by murine macrophage | 2005 | |
| Quantification of apoptosis and detection of HSP70 and COX-1 expression in tumor cells during Ehrlich ascites tumor growth | 2005 | |
| Atividade analgésica e antiedematogênica de Polygala paniculata L. (Polygalaceae) selvagem e obtida por micropropagação | 2005 | |
| Ability of eugenol to reduce tongue edema induced by Dieffenbachia picta Schott in mice | 10.1016/j.toxicon.2004.03.005 | 2004 |
| (±)-cis-(6-Ethyl-tetrahydropyran-2-yl)-formic acid: a novel substance with antinociceptive properties | 10.1016/j.bmcl.2003.12.075 | 2004 |
| Antinociceptive and free radical scavenging activities of Cocos nucifera L. (Palmae) husk fiber aqueous extract | 10.1016/j.jep.2004.03.013 | 2004 |
| Anti-inflammatory and analgesic activity of Bouchea fluminensis | 10.1016/S0367-326X(03)00049-2 | 2003 |
| In vivo andin vitro studies on the anticancer activity ofCopaifera multijuga hayne and its fractions | 10.1002/ptr.1295 | 2003 |
| Ação de extratos do açaí (Euterpe oleracea) sobre a produção de óxido nítrico em células RAW 264.7 | 2003 | |
| Ethnopharmacological evaluations on Brazilian Medicinal Plants | 2003 | |
| Atividade antinociceptiva de extratos de açaí (Euterpe oleraceae Mart.) | 2002 | |
| Chemistry of Euterpe palm and its pharmacological profile | 2001 | |
| Nitric oxide production by M.bovis BCG-infected pleural macrophages from BCGr and BCGs mouse strains | 2000 | |
| Depolymerization of macrophage filaments prevents induction and inhibits activity of nitric oxide synthase | 1997 | |
| Role of nitric oxide and superoxide in Giardia lamblia killing | 1996 | |
| Oxido Nitrico e sistema cardiovascular | 1994 | |
| Peptides potentiating kinin actions: a review | 1992 | |
| Inhibiton of rat paw edema and pleurisy by the extract from mandevilla velutina | 1991 | |
| Comparative effects of two potentiating peptides KPP and BPP9a on kinin-induced rat paw edema | 1991 | |
| Differential inhibition by two hetrazepine PAF antagonists of acute inflammation in the mouse | 1990 |
Eventos:
(0.00% eventos com DOI)