Julia Helena Rosauro Clarke

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Faculdade de Farmácia

Departamento:

Departamento de Biotecnologia Farmacêutica

ORCID:

não disponível no Lattes


Formação:

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2011 - 2014

  • Pontifícia Universidade Católica do Rio Grande do Sul

    | Pós-Doutorado | 2010 - 2011

  • Universidade Federal do Rio Grande do Sul

    Medicina: Ciências Médicas | Doutorado | 2008 - 2010

  • Universidade Federal do Rio Grande do Sul

    Farmácia Industrial | Especialização | 2006 - 2008

  • Universidade Federal do Rio Grande do Sul

    Ciências Biológicas (Neurociências) | Mestrado | 2006 - 2008

  • Universidade Federal do Rio Grande do Sul

    Farmácia | Graduação | 2001 - 2005

  • Colégio Farroupilha

    | Ensino Médio (2o grau) | 1998 - 2000

  • Colégio Farroupilha

    | Ensino Fundamental (1o grau) | 1990 - 1997
Laboratórios:
Nuvens de Palavras:
Artigos:

(95.12% artigos com DOI)

Titulo DOI Ano
ATP-P2X7 signaling mediates brain pathology while contributing to viral control in perinatal Zika virus infection   10.1016/j.bbi.2024.02.035 2024
Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome 10.1016/j.bbadis.2024.167097 2024
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice 10.1016/j.celrep.2023.112189 2023
Different outcomes of neonatal and adult Zika virus infection on startle reflex and prepulse inhibition in mice 10.1016/j.bbr.2023.114519 2023
Glutamatergic dysfunction as a central mechanism underlying flavivirus-induced neurological damage 10.1111/jnc.15935 2023
Mice lacking 5-lipoxygenase display motor deficits associated with cortical and hippocampal synapse abnormalities 10.1016/j.bbi.2021.12.004 2022
Lifelong Exposure to a Low-Dose of the Glyphosate-Based Herbicide RoundUp® Causes Intestinal Damage, Gut Dysbiosis, and Behavioral Changes in Mice 10.3390/ijms23105583 2022
Nanosystems for gene therapy targeting brain damage caused by viral infections 10.1016/j.mtbio.2022.100525 2022
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral 2 metabolic alterations in Alzheimer?s disease 10.1038/s41398-021-01349-z 2021
Innate immune memory mediates increased susceptibility to Alzheimer´s disease-like pathology in sepsis surviving mice 10.1016/j.bbi.2021.04.001 2021
Dissociation of genotype-dependent cognitive and motor behavior in a strain of aging mice devoid of the prion protein. 10.1016/j.bbr.2021.113386 2021
Skeletal muscle is an early site of Zika virus replication and injury impairing myogenesis 10.1128/JVI.00904-21 2021
SARS-CoV-2-associated cytokine storm during pregnancy as a possible risk factor for neuropsychiatric disorder development in post-pandemic infants 10.1016/j.neuropharm.2021.108841 2021
Prion protein complexed to a DNA aptamer induce behavioral and synapse dysfunction in mice 10.1016/j.bbr.2021.113680 2021
Palmitate is increased in the cerebrospinal fluid of obese humans and induces memory impairment in mice via pro-inflammatory TNF-α 10.1016/j.celrep.2020.01.072 2020
Modulation in phase and frequency of neural oscillations during epileptiform activity induced by neonatal Zika virus infection in mice 10.1038/s41598-020-63685-2 2020
Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer?s models 10.1038/s41591-018-0275-4 2019
Neonatal infection leads to increased susceptibility to Aβ oligomer-induced brain inflammation, synapse loss and cognitive impairment in mice 10.1038/s41419-019-1529-x 2019
Late neurological consequences of Zika virus infection: risk factors and pharmaceutical approaches 10.3390/ph12020060 2019
Combined oral contraceptive in female mice causes hyperinsulinemia due to B-cell hyper secretion and reduction in insulin clearance 10.1016/j.jsbmb.2019.03.018 2019
Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice 10.1038/s41467-019-11866-7 2019
Late Cognitive Consequences of Gestational Diabetes to the Offspring, in a New Mouse Model 10.1007/s12035-019-1624-0 2019
Metabolic Dysfunction in Alzheimer?s Disease: From Basic Neurobiology to Clinical Approaches 10.3233/JAD-179911 2018
The diabetes drug liraglutide reverses cognitive impairment in mice and attenuates insulin receptor and synaptic pathology in a non-human primate model of Alzheimer's disease 10.1002/path.5056 2018
Acute and chronic neurological consequences of early-life Zika virus infection in mice 10.1126/scitranslmed.aar2749 2018
Interaction of Aβ Oligomers with Neurexin 2α and Neuroligin 1 Mediates Synapse Damage and Memory Loss in Mice 10.1074/jbc.m116.761189 2017
Chronic sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-β oligomers in mice 10.1016/j.bbi.2017.04.007 2017
Consequences of gestational diabetes to the brain and behavior of the offspring 10.1590/0001-3765201720170264 2017
Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson?s disease-like symptoms in mice 10.1016/j.bbr.2017.06.047 2017
Temporal and Regional Expression of Glucose-Dependent Insulinotropic Peptide and Its Receptor in Spinal Cord Injured Rats 10.1089/neu.2015.3877 2016
Brain-Defective Insulin Signaling Is Associated to Late Cognitive Impairment in Post-Septic Mice 10.1007/s12035-016-0307-3 2016
Alzheimer-associated A  oligomers impact the central nervous system to induce peripheral metabolic deregulation 10.15252/emmm.201404183 2015
Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease 10.1016/j.jalz.2013.12.010 2014
Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A  Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers 10.1523/jneurosci.0482-13.2013 2013
TNF-α Mediates PKR-Dependent Memory Impairment and Brain IRS-1 Inhibition Induced by Alzheimer?s β-Amyloid Oligomers in Mice and Monkeys 10.1016/j.cmet.2013.11.002 2013
Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice 10.1038/mp.2012.168 2012
Plastic modifications induced by object recognition memory processing 10.1073/pnas.0915059107 2010
Extinction learning: neurological features, therapeutic applications, and effect of aging. 2008
Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs object recognition long-term memory 10.1016/j.nlm.2008.04.009 2008
The Role of the Entorhinal Cortex in Extinction: Influences of Aging 10.1155/2008/595282 2008
Inhibition of c-Jun N-terminal kinase in the CA1 region of the dorsal hippocampus blocks extinction of inhibitory avoidance memory 2007
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
A model of neonatal Zika virus infection for the study of neurodevelopmental disorders 2017
Brain infusion of alfa-synuclein iligomers induces motor and non motor Parkinson's disease-like symptoms 2017
Zika virus replicates in adult human and mouse brains, leading to brain inflammation, synapse loss and memory impairment in mice 2017
Brain defective insulin signaling is associated to late cognitive impairment in post-septic mice 2017
Chronic Sleep restriction promotes brain inflammation and synapse loss, and potentiates memory impairment induced by amyloid-beta oligomers in mice 2017
Caracterização de um modelo animal da doença de Parkinson com injeção intracerebroventricular de oligômeros de alda-sinucleina 2013
Oligômeros de Abeta relacionam comportamento depressivo com prejuízo cognitivo em camundongos 2013
Prejuízo Cognitivo e Alteração da Sinalização Insulinérgica no hipocampo de modelo experimental da sepse 2013
Differential impact of high and low molecular mass Aβ oligomers on synapse density, NMDA receptor activity and memory in mice 2012
Modulation of Hippocampal Noradrenaline Release by CB1 receptors activation during Object Recognition Memory Formation 2011
On the interplay between the noradrenergic system and CB1 receptors during the consolidation of object recognition memory in rats 2011
Plastic modifications induced by object recognition memory processing 2010
Activation of beta-adrenergic receptors in the hippocampus reverses the amnesic effect of CB1 receptors agonists 2010
Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs long-term object recongition memory 2008
Posttraining activation of CB1 cannabinoid receptors in the CA1 region of the dorsal hippocampus impairs long-term object recongition memory 2008
Dorsolateral and medial prefrontal cortex are necessary both working memory and long-term memory consolidation. 2007
Inhibition of c-Jun N-terminal kinase in the CA1 region of the hippocampus blocks exctinction of inhibitory avoidance memory 2007
On the role of PKCc on spatial memory processing 2006
A link between the role of two prefrontal areas in immediate memory and in long-term memory consolidation 2006
On the extinction and reaquisition of fear motivated memory 2006
A formação da Memória para o Labirinto Aquático de Morris requer síntese proteica na região CA1 do hipocampo dorsal de ratos 2004
A extinção da Memória para o Labirinto Aquático de Morris não requer síntese proteica na região CA1 do hipocampo dorsal de ratos 2004
Learning of a Fear Motivated Task Induces the phosforilation of hippocampal CREB through a Src and ERK1/2 dependent pathway 2004
Short-term memory expression does not affect expression or extinction of Long-term memory 2004
A atividade das Src quinases é necessária para a formação e Evocação da Memória para a Tarefa da esquiva Inibitória 2003
Publicações:
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