Tuane Cristine Ramos Goncalves Vieira

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Biologia Estrutural

e-mail:

tuane@bioqmed.ufrj.br

Linkedin:

Google Scholar:

ORCID:

https://orcid.org/0000-0002-3574-5411

Formação:

  • National Institutes of Health

    | Pós-Doutorado | 2012 - 2012

  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2009 - 2014

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 2005 - 2009

  • Universidade Federal do Rio de Janeiro

    Química Biológica | Mestrado | 2004 - 2005

  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas | Graduação | 2000 - 2004
Laboratórios:
Nuvens de Palavras:
Artigos:

(100.00% artigos com DOI)

Titulo DOI Ano
Interactions between Cytokines and the Pathogenesis of Prion Diseases: Insights and Implications 10.3390/brainsci14050413 2024
Prion meeting 2023: implications of a growing field 10.1080/19336896.2024.2343535 2024
What is the role of lipids in prion conversion and disease? 10.3389/fnmol.2022.1032541 2023
Enterovirus infection and its relationship with neurodegenerative diseases 10.1590/0074-02760220252 2023
Targeting Biomolecular Condensation and Protein Aggregation against Cancer 10.1021/acs.chemrev.3c00131 2023
AI and protein structure and function in neurological disease: relevance to disease management 10.1038/s41582-023-00840-z 2023
PrP meets alpha-synuclein: Molecular mechanisms and implications for disease 10.1111/jnc.15992 2023
Nucleic acid actions on abnormal protein aggregation, phase transitions and phase separation 10.1016/j.sbi.2022.102346 2022
Hexokinase 2: The preferential target of trehalose-6-phosphate over hexokinase 1 10.1002/jcb.30317 2022
Aminoquinolones and their benzoquinone dimer hybrids as modulators of prion protein conversion 10.3390/molecules27227935 2022
Phase separation of p53 precedes aggregation and is affected by oncogenic mutations and ligands 10.1039/D1SC01739J 2021
Rabbit PrP Is Partially Resistant to in vitro Aggregation Induced by Different Biological Cofactors 10.3389/fnins.2021.689315 2021
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil 10.3390/v13071370 2021
Second-Generation RT-QuIC Assay for the Diagnosis of Creutzfeldt-Jakob Disease Patients in Brazil 10.3389/fbioe.2020.00929 2020
The Status of p53 Oligomeric and Aggregation States in Cancer 10.3390/biom10040548 2020
Challenges and Advances in Antemortem Diagnosis of Human Transmissible Spongiform Encephalopathies 10.3389/fbioe.2020.585896 2020
Modulation of p53 and prion protein aggregation by RNA 10.1016/j.bbapap.2019.02.006 2019
Prion protein-coated magnetic beads: Synthesis, characterization and development of a new ligands screening method 10.1016/j.chroma.2014.12.014 2015
High-Pressure Chemical Biology and Biotechnology 10.1021/cr400204z 2014
The aggregation of mutant p53 produces prion-like properties in cancer 10.4161/pri.27776 2014
Heparin binding confers prion stability and impairs its aggregation 10.1096/fj.13-246777 2014
The role of RNA in mammalian prion protein conversion 10.1002/wrna.118 2012
Heparin Binding by Murine Recombinant Prion Protein Leads to Transient Aggregation and Formation of RNA-Resistant Species 10.1021/ja106725p 2011
Experimental approaches to the interaction of the prion protein with nucleic acids and glycosaminoglycans: Modulators of the pathogenic conversion 10.1016/j.ymeth.2010.12.002 2011
PrP interactions with nucleic acids and glycosaminoglycans in function and disease 10.2741/3611 2010
Ligand Binding and Hydration in Protein Misfolding: Insights from Studies of Prion and p53 Tumor Suppressor Proteins 10.1021/ar900179t 2009
Prion Protein Complexed to N2a Cellular RNAs through Its N-terminal Domain Forms Aggregates and Is Toxic to Murine Neuroblastoma Cells 10.1074/jbc.M802102200 2008
Acharan sulfate, the new glycosaminoglycan from Achatina fulica Bowdich 1822. Structural heterogeneity, metabolic labeling and localization in the body, mucus and the organic shell matrix 10.1111/j.1432-1033.2004.03989.x 2004
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
O PAPEL DA PROTEÍNA PRION E SEUS AGREGADOS NA FUNÇÃO MITOCONDRIAL EM MODELOS NEURAIS 2023
EFEITOS DA INFECÇÃO POR ENTEROVÍRUS SOBRE A AGREGAÇÃO DE PROTEÍNAS AMILÓIDES EM CÉLULAS SH-SY5Y 2023
AVALIAÇÃO DA ATIVIDADE ANTIPRION IN VITRO DE EXTRATOS HIDROALCOÓLICOS DE MORINGA OLEIFERA LAMARK (MORINGACEAE) 2023
AVALIAÇÃO DA INTERAÇÃO ENTRE PRP E Α-SINUCLEÍNA USANDO TÉCNICAS ESPECTROSCÓPICAS 2023
EFEITO DA PIPERINA NA AGREGAÇÃO DE P53 MUTANTE (R248Q) EM TUMORES NÃO SÓLIDOS 2023
Evaluation of the Effect of pH in Phosphatidic Acid-Induced Prion Conversion into Amyloid Fibrils 2023
EFFECTS OF ENTEROVIRUS INFECTION ON AMYLOID PROTEIN AGGREGATION IN SH-SY5Y CELLS. 2023
AVALIAÇÃO DO EFEITO DA INFECÇÃO POR SARS-COV-2 NA AGREGAÇÃO DE PROTEÍNAS AMILOIDOGÊNICAS EM CÉLULAS NEURAIS 2022
EFEITO DA PIPERINA SOBRE P53 SELVAGEM E MUTANTE (R248Q) EM TUMORES NÃO SÓLIDOS 2022
EFFECT OF PIPERINE ON MUTANT p53 (R248Q) AGGREGATION IN NON-SOLID TUMORS 2022
Evaluation of the Effect of pH in Phosphatidic Acid-Induced Prion Conversion into Amyloid Fibrils 2022
Heparin modulates p53 aggregation, leading to an aggregation route with amyloidogenic properties 2022
P53 PROTEIN AND LIQUID LIQUID PHASE SEPARATION (LLPS): AGGREGATION STUDIES IN ANTICANCER THERAPY 2021
EVALUATION OF BOVINE LACTOFERRIN AS AN ANTIPRION DRUG 2021
EVALUATION OF THE INTERACTION BETWEEN P53 TUMOR SUPPRESSOR PROTEIN AND HEPARIN 2021
BLF-PRP INTERACTION: THE ANTIPRION EFFECT OF BOVINE LACTOFERRIN 2021
Antiprionic activity of 6-aminoquinolones and their dimeric benzoquinone conjugates 2019
Avaiação estrutural e citotoxicidade dos agregados formados pela interação de vesículas lipídios com a proteína prion 2019
A conformação do domínio N-terminal da proteína prion é importante para direcionar sua rota de agregação 2019
Bovine Lactoferrin inhibits the fibrillation of prion protein 2019
ANALYZING THE INTERACTION BETWEEN PRION PROTEIN AND LIPID VESICLES 2019
STRUCTURAL AND CYTOTOXICITY EVALUATION OF AGGREGATES FORMED BY THE INTERACTION OF LIPID VESICLES WITH PRION PROTEIN 2019
RABBIT PRION PROTEIN INTERACTION WITH COFACTORS MAY TRIGGER RESISTANCE 2019
Interaction with phosphatidic acid leads to prion protein fibrilization 2019
Investigação da interação entre lactoferrina Bovina e prion através de técnicas espectroscópicas 2019
Bovine lactoferrin inhibits the fibrillization of prion protein 2019
A INTERAÇÃO DA PROTEÍNA PRÍON DE COELHO COM COFATORES PODE DESENCADEAR RESISTÊNCIA 2019
Conscientização patrimonial infantil acerca dos conceitos de memória a partir da atividade ?Doenças Neurodegenerativas: Restaurando Memórias? 2019
Characterization of the Prion Protein Fibrillization Pathway Induced by Phosphatidic Acid 2018
Does the rabbit prion protein interacts differently with biological cofactors? Is this the cause of resistance? 2018
EVALUATION OF THE INTERACTION BETWEEN PRION PROTEIN AND BOVINE LACTOFERRIN 2018
AVALIAÇÃO DA INTERAÇÃO ENTRE A PROTEÍNA PRION E LACTOFERRINA 2018
CARACTERIZAÇÃO DA VIA DE FORMAÇÃO DE FIBRAS DE PrP INDUZIDA PELO ÁCIDO FOSFATÍDICO 2018
A PROTEÍNA PRION DE COELHO INTERAGE DE FORMA DIFERENTE COM COFATORES BIOLÓGICOS? ESSA É A CAUSA DA RESISTÊNCIA? 2018
AVALIAÇÃO ESTRUTURAL DA INTERAÇÃO DE VESÍCULAS LIPÍDICAS COM A PROTEÍNA PRION 2018
CHARACTERIZATION OF THE PRION PROTEIN FIBRILLIZATION PATHWAY INDUCED BY PHOSPHATIDIC ACID 2018
INVESTIGATION OF THE INTERACTION BETWEEN PRION PROTEIN AND BOVINE LACTOFERRIN 2018
InvestigationoftheInteractionBetweenPrionProteinandBovineLactoferrin 2018
INVESTIGATION OF THE INTERACTION BETWEEN PRION PROTEIN AND BOVINE LACTOFERRIN 2018
INTERAÇÃO ENTRE LIPÍDIOS E A PROTEÍNA PRION 2017
AVALIAÇÃO ESTRUTURAL DA INTERAÇÃO ENTRE PROTEÍNA PRION DE COELHO E GLICOSAMINOGLICANOS 2017
PRION PROPAGATION: AGGREGATION INDUCED BY NEUTROPHIL EXTRACELLULAR TRAPS (NETS). 2017
INVESTIGATING THE INTERACTION BETWEEN PRION AND LIPIDS 2017
HIGHLY STABLE PRP FIBRILS FORMED BY INTERACTION WITH PHOSPHATIDIC ACID 2017
Structural Evaluation Of The Interaction Between Rabbit Prion Protein And Glycosaminoglycans 2017
PROPAGAÇÃO PRIÔNICA: CITOTOXICIDADE DE FIBRAS AMILÓIDES, AGREGADOS E OLIGÔMEROS DA PROTEÍNA PRION INDUZIDOS POR VESÍCULAS LIPÍDICAS 2017
The use of second generation RT-Quic assay for the diagnosis of Creutzfeldt Jakob Disease in Brazil: A pilot colaboration study 2017
FIBRAS DE PRP E A PROPAGAÇÃO DE DOENÇAS PRIÔNICAS ATRAVÉS DA AÇÃO DE DNA COMO COFATOR 2016
AGREGAÇÃO DA PROTEÍNA PRION DESENCADEADA POR ARMADILHAS EXTRACELULARES NEUTROFÍLICAS (NETS 2016
Prion Propagation, Nucleic Acids & Neutrophils: Prion Protein Aggregation Triggered by Neutrophil Extracellular Traps (NETS) 2016
Structural Analysis of Prion Fibrils Induced by Phosphatidic Acid 2016
Structural evaluation of the interaction between the prion protein and Ascidian dermatan sulfates 2016
AVALIAÇÃO DA INTERAÇÃO ENTRE A PROTEÍNA PRION E LIPÍDIOS DE IMPORTÂNCIA BIOLÓGICA 2015
PROPAGAÇÃO DE PRÍON: AGREGAÇÃO DESENCADEADA POR ARMADILHAS EXTRACELULARES NEUTROFÍLICAS (NETs) 2015
PRION PROPAGATION, NUCLEIC ACIDS & INNATE IMMUNITY: PRION PROTEIN AGGREGATION TRIGGERED BY NEUTROPHIL EXTRACELLULAR TRAPS (NETs) 2015
DiSSECTION OF PRION PROTEIN AND LIPID INTERACTION 2015
DISSECTION OF PRION PROTEIN AND LIPID INTERACTION 2015
Prion Protein aggregation Triggered By Neutrophil Extracellular Traps (NETs) 2014
Heparin binding confers prion stability and impairs its aggregation 2014
Heparin binding confers prion stability and impairs its aggregation 2014
Dissection Of Prion Protein And Lipid Interaction 2014
Prion Protein Aggregation Triggered By Neutrophil Extracellular Traps (NETs) 2013
Heparin Modulation of Prion Seeding Activity 2013
Heparin Modulation of Prion Seeding Activity 2013
Heparin Modulation of Prion Seeding Activity 2013
Heparin binding increases murine prion protein stability 2012
Heparin binding increases murine prion protein stability 2012
The effect of heparin length on interaction with the prion protein. 2011
Evaluation of the pathophysiological role of PrP:RNA interaction. 2011
O efeito do tamanho da heparina na interação com a proteína prion. 2011
O Envolvimento da Proteína Abl na Via Pró-Apoptótica Desencadeada pelo Peptídeo Beta-Amilóide na Doença de Alzheimer 2011
Heparin binding increases murine prion protein stability 2011
Prion protein interaction with low molecular weight heparin 2010
Insights on PrP interaction with RNA molecules 2010
Prion protein interaction with low molecular weight heparin 2010
Structural and physiological aspects of PRP interaction with RNA molecules 2010
EVALUATION OF PRION PROTEIN INTERACTION WITH HEPARIN REVEALS PH-DEPENDENT BINDING SITES 2009
PRION PROTEIN INTERACTION WITH HEPARIN 2009
THE PECULIAR INTERACTION BETWEEN MAMMALIAN PRION PROTEIN AND RNA 2009
THE PECULIAR INTERACTION BETWEEN MAMMALIAN PRION PROTEIN AND RNA 2009
HEPARIN EFFECT ON PRION PROTEIN STRUCTURE AND AGGREGATION 2009
Modulation of murine prion protein misfolding and aggregation mediated by RNA molecules 2009
Aspectos estruturais da interação entre a proteína do prion e heparina 2009
CHARACTERIZATION OF THE PRP:RNA COMPLEX: STRUCTURAL INSIGHTS AND TOXICITY STUDIES 2008
INVESTIGATION OF THE EFFECT OF HEPARIN ON PRION PROTEIN STRUCTURE 2008
Investigation of the effect of heparin on prion protein structure 2008
Characterization of the PrP:RNA complex: Structural insights and toxicity studies 2008
Dissection of prion protein and heparin interaction sites 2007
Structural insights into the interaction between prion protein and heparin 2007
Structural insights into the interaction between prion protein and heparin 2007
Structural insights into the interaction between prion protein and heparin. 2007
Aspectos estruturais da interação entre a proteína do prion e heparina 2007
Structural insights into the interaction between prion protein and heparin 2007
Structural insights on the interaction of prion protein with heparin 2006
Biophysical profile of prion protein interaction with heparin 2006
Identification of polisaccharides that may be involved in reproduction and development in the snail Achatina fulica (Bowdich 1822) 2005
Identification of polisaccharides that may be involved in reproduction and development in the snail Achatina fulica (Bowdich 1822) 2005
Biochemical characterization of sulfated polysaccharides from the body of four species of earthworms (Annelida, Oligochaeta) and histochemistry of their integument 2005
Introduzindo a genética no ensino fundamental: uma experiência de prática de ensino realizada no CAp/UFRJ 2005
Composição de polissacarídeos sulfatados no corpo da minhoca da espécie Ponthoscolex corethrurus nos estágios jovem e adulto 2005
Polissacarídeos sulfatados extraídos do corpo da minhoca Pontoscolex corethrurus (Oligochaeta, Annelida) revelam uma grande heterogeneidade na expressão dessas moléculas nesses invertebrados 2004
Isolamento e caracterização parcial dos polissacarídeos presentes nos ovos do caracol Achatina fulica Bowdich, 1822 2004
Compartmental distribution of acharan sulfate in the body of the snail Achatina fulica (Bowdich,1822) 2004
ACHARAN SULFATE, THE GIANT AFRICAN SNAIL GAG: Structural heterogeneity, metabolic labeling and distribution among the whole body, mucus and the organic shell matrix. 2003
ACHARAN SULFATE, THE GIANT AFRICAN SNAIL GAG: Structural heterogeneity, metabolic labeling and distribution among the whole body, mucus and the organic shell matrix. 2003
Sulfated polysaccharides from Annelid worms: Eisenia foetida and Eudrilus eugeniae (Oligochaeta) and Demonax sp. (Polichaeta) 2002
Isolamento de um novo polissacarídeo altamente sulfatado do corpo do caracol Achatina fulica. 2001
Isolation of a new highly sulfated polysaccharide from the soft body of the african giant snail Achatina fulica 2001
Occurrence of Heparan sulfate and/or Heparin and Chondroitin sulfate glycosaminoglycans in the body of two species of earthworms: Eisenia foetida and Eudrilus eugeniae (Oligochaeta, Annelida) 2001
Ocorrência de Heparan sulfato e ou Heparina e Condroitin sulfato no corpo de duas espécies de minhoca: Eisenia foetida e Eudrilus eugeniae (Oligochaeta, Annelida) 2001
Gravidez de risco 2000
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