Leonardo Nogueira
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Bioquímica Médica
Departamento:
Programa de Biologia Celular e Biofisica
Formação:
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Universidade da California San Diego
| Pós-Doutorado | 2009 - 2013
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Duke University
| Pós-Doutorado | 2008 - 2009
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Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 2003 - 2008
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Universidade Federal do Rio de Janeiro
Química Biológica | Mestrado | 2001 - 2003
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Universidade Federal do Rio de Janeiro
Educação Física | Graduação | 1996 - 2000
Laboratórios:
Nuvens de Palavras:
Artigos:
(100.00% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Role of parvalbumin in fatigue-induced changes in force and cytosolic calcium transients in intact single mouse myofibers | 10.1152/japplphysiol.00861.2021 | 2022 |
| E-cigarette aerosol impairs male mouse skeletal muscle force development and prevents recovery from injury | 10.1152/ajpregu.00314.2021 | 2022 |
| Cigarettes Make You Weak: RANKL/RANK Link Changes in Muscle and Bone | 10.1165/rcmb.2021-0098ED | 2021 |
| Role of IL-33 receptor (ST2) deletion in diaphragm contractile and mitochondrial function in the Sugen5416/hypoxia model of pulmonary hypertension | 10.1016/j.resp.2021.103783 | 2021 |
| Response to Lamb and Stephenson | 10.1113/JP279621 | 2020 |
| Influence of muscle oxygenation and nitrate-rich beetroot juice supplementation on O2 uptake kinetics and exercise tolerance | 10.1016/j.niox.2020.03.007 | 2020 |
| Incubation with sodium nitrite attenuates fatigue development in intact single mouse fibres at physiological PO | 10.1113/JP278494 | 2019 |
| A mitochondrial-targeted antioxidant improves myofilament Ca sensitivity during prolonged low frequency force depression at low PO | 10.1113/JP275470 | 2018 |
| Cigarette smoke directly impairs skeletal muscle function through capillary regression and altered myofiber calcium kinetics in mice | 10.1113/JP275888 | 2018 |
| Balance between S-nitrosylation and denitrosylation modulates myoblast proliferation independently of soluble guanylyl cyclase activation | 10.1152/ajpcell.00140.2016 | 2017 |
| S-nitrosylation of sarcomeric proteins depresses myofilament Ca2+ sensitivity in intact cardiomyocytes | 10.1089/ars.2015.6275 | 2015 |
| Effects of (−)-epicatechin on molecular modulators of skeletal muscle growth and differentiation | 10.1016/j.jnutbio.2013.09.007 | 2014 |
| Skeletal Myofiber VEGF Is Essential for the Exercise Training Response In Adult Mice | 10.1152/ajpregu.00522.2013 | 2014 |
| Recovery of Indicators of Mitochondrial Biogenesis, Oxidative Stress, and Aging With (-)-Epicatechin in Senile Mice | 10.1093/gerona/glu131 | 2014 |
| Ca2+-Pumping Impairment during Repetitive Fatiguing Contractions in Single Myofibers: Role of Cross-Bridge Cycling | 10.1152/ajpregu.00178.2013 | 2013 |
| (−)-Epicatechin rich cocoa mediated modulation of oxidative stress regulators in skeletal muscle of heart failure and type 2 diabetes patients | 10.1016/j.ijcard.2013.06.089 | 2013 |
| Impaired exercise capacity and skeletal muscle function in a mouse model of pulmonary inflammation | 10.1152/japplphysiol.00607.2012 | 2013 |
| Mitochondrial activation at the onset of contractions in isolated myofibres during successive contractile periods | 10.1113/jphysiol.2012.232405 | 2012 |
| Stimulatory effects of the flavanol (-)-epicatechin on cardiac angiogenesis | 10.1097/FJC.0b013e318269ae0d | 2012 |
| Effect of Pulmonary TNF-alfa Overexpression on Mouse Isolated Skeletal Muscle Function | 10.1152/ajpregu.00126.2011 | 2011 |
| Oxygen-coupled redox regulation of the skeletal muscle ryanodine receptor-Ca2+ release channel by NADPH oxidase 4 | 10.1073/pnas.1109546108 | 2011 |
| Reactive Oxygen Species Formation during Tetanic Contractions in Single Isolated Xenopus Myofibers | 10.1152/japplphysiol.00398.2011 | 2011 |
| (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle | 10.1113/jphysiol.2011.209924 | 2011 |
| Phenol increases intracellular [Ca2+] during twitch contractions in intact Xenopus skeletal myofibers | 10.1152/japplphysiol.00660.2010 | 2010 |
| Proteomic analysis of S-nitrosylation and denitrosylation by resin-assisted capture | 10.1038/nbt.1545 | 2009 |
| Myosin is reversibly inhibited by S-nitrosylation | 10.1042/BJ20091144 | 2009 |
Eventos:
(7.84% eventos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| Enhanced O2-Dependent Mitochondrial Activation in Myofibers from CMP N-Glycolylneuraminic Acid Hydroxylase (Cmah) Gene Inactivated Mice | 2020 | |
| Inhibition of S‐nitrosoglutathione Reductase During Contractions Slows Recovery of Low‐Frequency Force in Isolated Fast‐twitch Muscle and in Intact Single Myofibers | 2020 | |
| Cigarette Smoke Exposure in Mice Impairs Force Development of Injured Fast‐Twitch Skeletal Muscles | 2020 | |
| Effects of S-nitrosoglutathione Reductase Inhibition on Post-Fatigue Force and Intracellular Ca2+ in Intact Single Myofibers | 2020 | |
| Satellite cell incorporation in myofibers from anterior crural muscles of Pax7CreERTdTomato transgenic mice during the recovery of lengthening contractions. | 2020 | |
| Satellite cell incorporation in myofibers from anterior crural muscles of Pax7CreERTdTomato transgenic mice during the recovery of lengthening contractions. | 2020 | |
| Nitric oxide dependent delay in post-fatigue contractile recovery in isolated fast-twitch muscle: The role of the S-nitrosoglutathione reductase | 2019 | |
| Acute inhibition of the S-nitrosoglutathione reductase (GSNOR) in isolated fast-twitch muscle delays the contractile recovery post-fatigue | 2018 | |
| Overexpression of Perm1 in skeletal muscles recovers the denervationinduced decrease in mitochondrial proteins but did not alter the changes in muscle contractility | 2018 | |
| Fatigue-induced changes in intracellular calcium transients in single myofibers from parvalbumin conditional knockout mice | 2018 | |
| (+)-Epicatechin Stimulates Mitochondria Biogenesis Related Pathways Leading To Improved Exercise Performance In Rats | 2018 | |
| The role of GSNOR during the differentiation of C2C12 cells | 2018 | |
| The glutathione recycling system is a regulator of myotube contraction-induced GLUT4 translocation to the plasma membrane | 2017 | |
| Nitric Oxide and cGMP Increases Proliferation of Skeletal Muscle Cells | 2017 | |
| S-nitrosoglutathione reductase modulates myoblast proliferation and fusion independently of sGC activation | 2017 | |
| Inibição da S-nitrosoglutationa redutase em mioblastos diferenciados promove um aumento transiente de S-nitrosoproteínas | 2016 | |
| Role of S-nitrosoglutathione reductase on controling protein S-nitrosylation during myogenesis in primary cultures of muscle progenitor cells | 2016 | |
| S-nitrosoglutathione reductase and S-nitrosocyateine modulate myoblast proliferation and fusion | 2015 | |
| Effects of intraperitoneal injections of cigarette smoke extract on isolated skeletal muscle contractility | 2015 | |
| Chronic treatment with cigarette smoke extract exacerbates the fatigue-induced slowing of relaxation and Ca2+-uptake in single mouse fibers | 2015 | |
| Endotoxemia aguda aumenta a formação de S-nitrosotióis em proteínas contráteis do músculo cardíaco | 2015 | |
| Efeitos de injeções intraperitoneais de extrato de fumaça de cigarro na contratilidade de músculos esqueléticos locomotores | 2015 | |
| Cigarette smoke impairs the in situ fatigue resistance of locomotor skeletal muscle in mice | 2014 | |
| S-Nitrosylation Decreases Ca2+ Sensitivity and Actomyosin ATPase Activity of Contractile Proteins in Cardiac Myofibrils | 2013 | |
| Sodium Nitrite Incubation at Physiological PO2 Increases Fatigue Resistance in Intact Single Mouse Fibers | 2013 | |
| A Mitochondrial Targeted antioxidant Improves Forcerecovery after Fatigue In Intact single Myofibers at Low PO2 | 2013 | |
| Effect of hypoxia on single skeletal muscle fiber contractility at physiological temperature | 2012 | |
| Skeletal myofiber-expressed VEGF is required for adaptation to exercise training | 2012 | |
| NAD(P)H Kinetics at onset of contractions in single myofibers: Effect of prior contractions | 2012 | |
| Acute Oxaloacetate Exposure Enhances Resistance to Fatigue in in vitro Mouse Soleus Muscle | 2011 | |
| Effects of low PO2 on contractile and Ca2+ kinetics during fatigue in single mouse myofibers at 35ºC | 10.1249/01.MSS.0000402776.13559.4d | 2011 |
| Overexpression of TNF-alfa reduces skeletal muscle functions in mice under low PO2 condition | 10.1249/01.MSS.0000402777.21182.43 | 2011 |
| Phenol increases twitch tension by increasing Ca2+ transients in intact single Xenopus myofibers | 2010 | |
| Effect of Cross-Bridge Cycling Inactivation on Calcium Handling During Fatigue in Single Skeletal Muscle Fibers | 10.1249/01.MSS.0000386557.02264.33 | 2010 |
| Reactive Oxygen Species Formation during Tetanic Contractions Inducing Fatigue in Single Isolated Xenopus Myofibers | 10.1249/01.MSS.0000389359.98999.31 | 2010 |
| Acute Exposure to (-)-epicatechin does not Affect Resistance to Fatigue in Single Isolated Xenopus Myofibers | 2010 | |
| Oxaloacetate enhances resistance to fatigue in in vitro mouse soleus muscle | 2010 | |
| S-nitrosylation of myosin by NO is regulated by oxygen pressure (pO2) | 2010 | |
| S-nitrosation of skeletal muscle contractile proteins reduces Ca2+ sensitivity and inhibits myosin activity in vitro | 2009 | |
| Excesso de glicose-6-fosfato é prejudicial para a função da miosina | 2008 | |
| Myosin forms S-nitrosothiols by transnitrosation and is a target of S-nitrosation in skinned muscle fibers | 2008 | |
| Glycation affects myosin subfragment-1 ATPase activity | 2008 | |
| Myosin and actin of skinned skeletal muscle fibers are targets for S-nitrosylation. | 2007 | |
| Myosin activity is reduced by S-nitrosation being an important target for nitrosative stress in skinned muscle fibers. | 2007 | |
| S-nitrosation forms labile ?SNO bonds that affect Mg2+ATPase activity of skeletal muscle myosin. | 2006 | |
| Putative effects of nitric oxide on skeletal muscle 6-phosphofructo-1-kinase regulation | 2005 | |
| Phenol increases Ca2+ sensitivity in mammalian skinned fibers and uncouples the actomyosin ATPase activity without affecting Ca2+ binding to troponin C. | 2004 | |
| Characterization of S-nitrosylation in skeletal muscle myosin and its effects on ATPase activity. | 2003 | |
| Effects of nitric oxide donors on contractile properties of | 2002 | |
| Effects of phenol on Ca2+-induced tension in skinned fast- and slow-twitch skeletal muscle fibers of rabbit. | 2001 | |
| Efeitos putativos do óxido nítrico (NO) na tensão isométrica máxima em fibras musculares de contração rápida quimicamente descascadas. | 2001 |