Luiz Eduardo Baggio Savio
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Programa de Imunobiologia/Biof
Formação:
-
Universidade Federal do Rio de Janeiro
| Pós-Doutorado | 2016 - 2016
-
Universidade Federal do Rio de Janeiro
| Pós-Doutorado | 2016 - 2018
-
Universidade Federal do Rio de Janeiro
Ciências Biológicas (Biofísica) | Doutorado | 2012 - 2016
-
Universidade Federal do Rio Grande do Sul
Ciências Biológicas (Bioquímica) | Mestrado | 2010 - 2012
-
Pontifícia Universidade Católica do Rio Grande do Sul
Ciências Biológicas | Graduação | 2006 - 2009
Laboratórios:
Nuvens de Palavras:
Artigos:
(100.00% artigos com DOI)
Titulo | DOI | Ano |
---|---|---|
P2Y2-P2X7 receptors cross-talk in primed mesenteric endothelial cells upregulates NF-κB signaling favoring mononuclear cell adhesion in schistosomiasis | 10.3389/fimmu.2023.1328897 | 2024 |
Altered purinergic P2X7 and A2B receptors signaling limits macrophage-mediated host defense in schistosomiasis | 10.1016/j.bj.2024.100713 | 2024 |
ATP-P2X7 signaling mediates brain pathology while contributing to viral control in perinatal Zika virus infection | 10.1016/j.bbi.2024.02.035 | 2024 |
High mobility group box 1, |
10.1111/cts.13475 | 2023 |
The role of NOD-like receptors in innate immunity | 10.3389/fimmu.2023.1122586 | 2023 |
SARS-CoV-2 spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID syndrome in mice | 10.1016/j.celrep.2023.112189 | 2023 |
SARS-CoV-2 Spike protein alters microglial purinergic signaling | 10.3389/fimmu.2023.115846 | 2023 |
P2X7 receptor contributes to long-term neuroinflammation and cognitive impairment in sepsis-surviving mice | 10.3389/fphar.2023.1179723 | 2023 |
Cysteinyl-leukotrienes promote cutaneous Leishmaniasis control | 10.3389/fcimb.2023.1192800 | 2023 |
Editorial: Inflammasome, purinergic signaling, and immunometabolism in oral health and disease | 10.3389/froh.2023.1236507 | 2023 |
Effect of Quinolinic Acid on Behavior, Morphology, and Expression of Inflammatory/oxidative Status in Rats? Striatum: Is Coenzyme Q10 a Good Protector? | 10.1007/s12640-023-00656-1 | 2023 |
Purinergic signaling in the battlefield of viral infections | 10.1007/s11302-023-09981-8 | 2023 |
Folic acid supplementation during pregnancy alters behavior in male rat offspring: nitrative stress and neuroinflammatory implications | 10.1007/s12035-022-02724-7 | 2022 |
P2X7 Receptor Triggers Lysosomal Leakage Through Calcium Mobilization in a Mechanism dependent on Pannexin-1 Hemichannels | 10.3389/fimmu.2022.752105 | 2022 |
Extracellular Nucleotides on Lymphocyte Function | 10.3389/fcell.2022.892303 | 2022 |
Rivastigmine Reverses the Decrease in Synapsin and Memory Caused by Homocysteine: Is There Relation to Inflammation? | 10.1007/s12035-022-02871-x | 2022 |
Purinergic signaling: A new front-line determinant of resistance and susceptibility in leishmaniasis | 10.1016/j.bj.2021.06.003. | 2022 |
P2X receptors in the balance between inflammation and pathogen control in sepsis | 10.1007/s11302-022-09870-6 | 2022 |
The blockage of downstream P2Y2 receptor signaling inhibits the prostate cancer cell adhesion to endothelial cells | 10.1016/j.lfs.2022.120793 | 2022 |
High-protein nutrition during pregnancy increases neuroinflammation and homocysteine levels and impairs behavior in male adolescent rats offspring | 10.1016/j.lfs.2022.121084 | 2022 |
Targeting Purinergic Signaling in the Dynamics of Disease Progression in Sepsis | 10.3389/fphar.2020.626484 | 2021 |
Ectonucleotidase Modulation of Lymphocyte Function in Gut and Liver | 10.3389/fcell.2020.621760 | 2021 |
Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents | 10.1016/j.lfs.2021.119386 | 2021 |
Innate immune memory mediates increased susceptibility to Alzheimer?s disease-like pathology in sepsis surviving mice | 10.1016/j.bbi.2021.04.001 | 2021 |
Purinergic signalling in host innate immune defence against intracellular pathogens | 10.1016/j.bcp.2021.114405 | 2021 |
Purinergic signaling in the modulation of redox biology | 10.1016/j.redox.2021.102137 | 2021 |
P2X7 receptor activation increases expression of caveolin-1 and formation of macrophage lipid rafts, thereby boosting CD39 activity | 10.1242/jcs.237560 | 2020 |
Purinergic signaling in infectious diseases of the central nervous system | 10.1016/j.bbi.2020.07.026 | 2020 |
P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion | 10.1155/2020/2545682 | 2020 |
P2X7 receptor deletion attenuates oxidative stress and liver damage in sepsis | 10.1007/s11302-020-09746-7 | 2020 |
Creatine supplementation impairs airway inflammation in an experimental model of asthma involving P2 × 7 receptor | 10.1002/eji.201847657 | 2019 |
Immunomodulatory effects of P2X7 receptor in intracellular parasite infections | 10.1016/j.coph.2019.02.005 | 2019 |
Disruption of Purinergic Receptor P2X7 Signaling Increases Susceptibility to Cerebral Toxoplasmosis | 10.1016/j.ajpath.2019.01.001 | 2019 |
The P2X7 receptor in inflammatory diseases: Angel or demon? | 10.3389/fphar.2018.00052 | 2018 |
Intralesional uridine-5--triphosphate (UTP) treatment induced resistance to Leishmania amazonensis infection by boosting Th1 immune responses and reactive oxygen species production | 10.1007/s11302-018-9606-7 | 2018 |
P2-×-7-mediated leukocyte recruitment and Porphyromonas gingivalis clearance requires IL-1β production and autocrine IL-1 receptor activation | 10.1016/j.imbio.2018.10.008 | 2018 |
P2X7 receptor promotes intestinal inflammation in chemically induced colitis and triggers death of mucosal regulatory T cells | 10.1016/j.bbadis.2017.03.004 | 2017 |
CD39 Limits P2X7 Receptor Inflammatory Signaling and Attenuates Sepsis-Induced Liver Injury | 10.1016/j.jhep.2017.05.021 | 2017 |
Potential role of P2X7R in esophageal squamous cell carcinoma proliferation | 10.1007/s11302-017-9559-2 | 2017 |
Multifaceted Effects of Extracellular Adenosine Triphosphate and Adenosine in the Tumor-Host Interaction and Therapeutic Perspectives | 10.3389/fimmu.2017.01526 | 2017 |
Hyperthermia and associated changes in membrane fluidity potentiate P2X7 activation to promote tumor cell death | 10.18632/oncotarget.18595 | 2017 |
P2X7 Receptor Signaling Contributes to Sepsis-Associated Brain Dysfunction | 10.1007/s12035-016-0168-9 | 2017 |
Inflammatory early events associated to the role of P2X7 receptor in acute murine toxoplasmosis | 10.1016/j.imbio.2016.12.007 | 2017 |
The role of the P2X7 receptor in murine cutaneous leishmaniasis: aspects of inflammation and parasite control | 10.1007/s11302-016-9544-1 | 2017 |
Increased expression of NTPDases 2 and 3 in mesenteric endothelial cells during schistosomiasis favors leukocyte adhesion through P2Y1 receptors | 10.1016/j.vph.2016.02.005 | 2016 |
Purinergic signaling in infection and autoimmune disease | 10.1016/j.bj.2016.09.002 | 2016 |
Methionine Exposure Alters Glutamate Uptake and Adenine Nucleotide Hydrolysis in the Zebrafish Brain | 10.1007/s12035-014-8983-3 | 2016 |
The role of P2X7 receptor in infectious inflammatory diseases and the influence of ectonucleotidases | 10.4103/2319-4170.127803 | 2014 |
Macrophage P2X7 Receptor Function Is Reduced during Schistosomiasis: Putative Role of TGF- β 1 | 10.1155/2014/134974 | 2014 |
Mild Hyperhomocysteinemia Increases Brain Acetylcholinesterase and Proinflammatory Cytokine Levels in Different Tissues | 10.1007/s12035-014-8660-6 | 2014 |
The effect of exercise on the oxidative stress induced by experimental lung injury. | 10.1016/j.lfs.2012.12.005 | 2013 |
Mild hyperhomocysteinemia reduces the activity and immunocontent, but does not alter the gene expression, of catalytic α subunits of cerebral Na+,K+-ATPase | 10.1007/s11010-013-1598-6 | 2013 |
Proline-induced changes in acetylcholinesterase activity and gene expression in zebrafish brain: reversal by antipsychotic drugs | 10.1016/j.neuroscience.2013.07.004 | 2013 |
Secondary metabolism in micropropagated Hypericum perforatum L. grown in non-aerated liquid medium | 10.1007/s11240-011-0058-9 | 2012 |
Endotoxin-induced effects on nucleotide catabolism in mouse kidney | 10.1016/j.ejphar.2011.11.002 | 2012 |
MK-801 alters Na+, K+-ATPase activity and oxidative status in zebrafish brain: reversal by antipsychotic drugs | 10.1007/s00702-011-0745-z | 2012 |
Behavioral changes induced by long-term proline exposure are reversed by antipsychotics in zebrafish | 10.1016/j.pnpbp.2011.10.002 | 2012 |
Chronic mild hyperhomocysteinemia alters ectonucleotidase activities and gene expression of ecto-5¿-nucleotidase/CD73 in rat lymphocytes | 10.1007/s11010-011-1141-6 | 2012 |
Long-term methionine exposure induces memory impairment on inhibitory avoidance task and alters acetylcholinesterase activity and expression in zebrafish (Danio rerio) | 10.1007/s11064-012-0749-6 | 2012 |
Long-term proline exposure alters nucleotide catabolism and ectonucleotidase gene expression in zebrafish brain | 10.1007/s11011-012-9321-y | 2012 |
Mild Hyperhomocysteinemia Alters Extracellular Adenine Metabolism in Rat Brain | 10.1016/j.neuroscience.2012.07.035 | 2012 |
Adenosine A2A receptor agonist (CGS-21680) prevents endotoxin-induced effects on nucleotidase activities in mouse lymphocytes | 10.1016/j.ejphar.2010.11.003 | 2011 |
Nucleoside triphosphate diphosphohydrolases role in the pathophysiology of cognitive impairment induced by seizure in early age | 10.1016/j.neuroscience.2011.01.065 | 2011 |
Endotoxemia alters nucleotide hydrolysis in platelets of rats | 10.1080/09537100802657743 | 2009 |
Eventos:
(0.00% eventos com DOI)