Norton Heise

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Biofísica Carlos Chagas Filho

Departamento:

Programa de Biologia Celular e Parasitária/Biof

ORCID:

https://orcid.org/0000-0003-0154-7406


Formação:

  • State University of New York

    | Pós-Doutorado | 2022 - 2023

  • University of Oklahoma

    | Pós-Doutorado | 2005 - 2007

  • Christian de Duve Institute Of Cellular Pathology

    | Pós-Doutorado | 1995 - 1997

  • Universidade Federal de São Paulo

    Microbiologia e Imunologia | Doutorado | 1990 - 1995

  • Universidade de São Paulo

    Ciências Biológicas | Graduação | 1984 - 1989
Laboratórios:
Nuvens de Palavras:
Artigos:

(72.73% artigos com DOI)

Titulo DOI Ano
Identification and Characterization of a Glycoside Hydrolase Family 9 Member from the Digestive Gland of the Snail Achatina fulica 10.1007/s12155-021-10303-2 2021
Endocytosis and Exocytosis in Leishmania amazonensis Are Modulated by Bromoenol Lactone 10.3389/fcimb.2020.00039 2020
Venom alkaloids against Chagas disease parasite: search for effective therapies 10.1038/s41598-020-67324-8 2020
Plasmodium falciparum Invasion and Intraerythrocytic Development are Impaired by 2´, 3´-Dialdehyde Adenosine 10.1016/j.micinf.2017.11.015 2018
Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi 10.3389/fimmu.2018.00671 2018
Tamoxifen inhibits the biosynthesis of inositolphosphorylceramide in Leishmania 10.1016/j.ijpddr.2018.10.007 2018
H+-dependent inorganic phosphate uptake in Trypanosoma brucei is influenced by myo-inositol transporter 10.1007/s10863-017-9695-y 2017
Hyperglycemia exacerbates colon cancer malignancy through hexosamine biosynthetic pathway 10.1038/oncsis.2017.2 2017
POM-1 inhibits P2 receptors and exhibits anti-inflammatory effects in macrophages 10.1007/s11302-017-9588-x 2017
Capsular polysaccharides from Cryptococcus neoformans modulate production of neutrophil extracellular traps (NETs) by human neutrophils 10.1038/srep08008 2015
Infection with Leishmania major Induces a Cellular Stress Response in Macrophages 10.1371/journal.pone.0085715 2014
Golgi UDP-GlcNAc:polypeptide O- -N-acetyl-D-glucosaminyltransferase-2 (TcOGNT2) regulates trypomastigote production and function in Trypanosoma cruzi 10.1128/EC.00165-14 2014
2´,3´-Dialdehyde of ATP, ADP, and Adenosine Inhibit HIV-1 Reverse Transcriptase and HIV-1 Replication 10.2174/1570162x12666140826105824 2014
Molecular and functional characterization of the ceramide synthase from Trypanosoma cruzi 10.1016/j.molbiopara.2011.12.006 2012
Acidocalcisomes as Calcium- and Polyphosphate-Storage Compartments during Embryogenesis of the Insect Rhodnius prolixus Stahl 10.1371/journal.pone.0027276 2011
The Sphingolipid Biosynthetic Pathway Is a Potential Target for Chemotherapy against Chagas Disease 10.4061/2011/648159 2011
Na+-ATPase and protein kinase C are targets to 1-O-hexadecylphosphocholine (miltefosine) in Trypanosoma cruzi 10.1016/j.abb.2008.10.018 2009
Molecular analysis of a UDP-GlcNAc:polypeptide α-N-acetylglucosaminyltransferase implicated in the initiation of mucin-type O-glycosylation in Trypanosoma cruzi 10.1093/glycob/cwp068 2009
The toxic effects of piperine against Trypanosoma cruzi: ultrastructural alterations and reversible blockage of cytokinesis in epimastigote forms 10.1007/s00436-008-0876-9 2008
Chemical Structure of Major Glycoconjugates from Parasites 2008
Nitrogen-fixing bacterium Burkholderia brasiliensis produces a novel yersiniose A-containing O-polysaccharide 2005
Characterization of the inositol phosphorylceramide synthase activity from Trypanosoma cruzi 10.1042/bj20041842 2005
Cloning and characterization of the phosphoglucomutase of Trypanosoma cruzi and functional complementation of a Saccharomyces cerevisiae PGM null mutant. 2005
Protozoan parasite-specific carbohydrate structures 10.1016/j.sbi.2005.08.011 2005
B cell response during infection with the MAT a and MAT alpha mating types of Cryptococcus neoformans 10.1016/j.micinf.2004.09.009 2005
Glycoinositolphospholipids from Trypanosoma cruzi: structure and biosynthesis 2004
Toxic effects of natural piperine and its derivatives on epimastigotes and amastigotes of Trypanosoma cruzi 10.1016/j.bmcl.2004.04.019 2004
Molecular analysis of a novel family of complex glycoinositolphosphoryl ceramides from Cryptococcus neoformans: structural differences between encapsulated and acapsular yeast forms 10.1093/glycob/cwf053 2002
Proinflammatory and Cytotoxic Effects of Hexadecylphosphocholine (Miltefosine) against Drug-Resistant Strains of Trypanosoma cruzi 10.1128/aac.46.11.3472-3477.2002 2002
Structure of an acidic exopolysaccharide produced by the diazotrophic endophytic bacterium Burkholderia brasiliensis 10.1046/j.1432-1327.2001.02196.x 2001
Characterization of novel structures of mannosylinositolphosphorylceramides from the yeast forms of Sporothrix schenckii 10.1046/j.1432-1327.2001.02339.x 2001
Localisation of a 3-hydroxy-3-methyl-glutaryl-CoA reductase in the mitochondrial matrix of Trypanosoma brucei procyclics 2000
Ether-lipid (alkyl-phospholipid) metabolism and the mechanism of action of ether-lipid analogues in Leishmania 10.1016/s0166-6851(00)00278-4 2000
Purification, localisation and characterisation of glucose-6-phosphate dehydrogenase of Trypanosoma brucei 10.1016/s0166-6851(98)00176-5 1999
The dihydroxyacetonephosphate pathway for biosynthesis of ether lipids in Leishmania mexicana promastigotes 10.1016/s0166-6851(97)00101-1 1997
Identification Of Complete Precursors Of Glycosylphosphatidylinositol Protein Anchors Of Trypanosoma Cruzi 1996
Characterization of the lipid moiety of the glycosylphosphatidylinositol anchor of Trypanosoma cruzi 1G7-antigen 10.1016/0166-6851(95)00009-p 1995
Paracoccidioides Brasiliensis Expresses Both Glycosylphosphatidylinositol Anchored Proteins And A Potent Phospholipase C 1995
Characterization Of A Phospholipase C-Resistant Inositol Containing Glycolipid From Trypanosoma Cruzi 1994
Rabbit Knee-Joint Meniscal Proteoglycans 1994
Age-Related Changes In Glycosaminoglycan Distribution In Different Anatomical Sites On The Surface Of Knee-Joint Articular Cartilage In Young Rabbits 1993
Mucin-like glycoproteins linked to the membrane by glycosylphosphatidylinositol anchor are the major acceptors of sialic acid in a reaction catalyzed by trans-sialidase in metacyclic forms of Trypanosoma cruzi 10.1016/0166-6851(93)90227-o 1993
Proteins Anchored Via Glycosylphosphatidylinositol And Solubilizing Phospholipases In Trypanosoma Cruzi 1993
Glycosaminoglycans In The Synovial Fluids Of Patients With Juvenile Rheumatoid Arthritis 1991
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Cloning and characterization of the phosphoglucomutase of Trypanosoma cruzi and functional complementation of a Saccharomyces cerevisiae PGM null mutant 2005
Functional analysis of a UDP-GlcNAc:Thr polypeptide N-acetyl-D-glucosaminyltransferase-like gene in Trypanosoma cruzi 2005
Homologs of the the yeast longevety-assurance gene (Lag-1) in Trypanosoma cruzi: unravelling the mechanisms of ceramide biosynthesis 2004
A comparative study of the effects of Lithium on the monossaccharide metabolism of Cryptococcus neoformans, Candida albicans and Schizosaccharomyces pombe 2004
Heterologous expression of Trypanosoma cruzi phosphoglucomutase (PGM) in Saccharomyces cerevisiae and functional complementation of yeast PGM null-mutant 2004
Cloning and molecular characterization of a putative UDP-N-acetylglucosamine:polypeptide alpha-N-acetylglucosaminyl transferase gene from Trypanosoma cruzi 2004
UDP-N-acetylglucosamine:polypeptide N-acetylglucosaminyltransferase (ppGlcNAcT) from Crithidia fasciculata 2004
Miltefosine inhibits the Na+-ATPase activity insensitive to Ouabain of Trypanosoma cruzi 2004
Trypanosoma cruzi trans-sialidase sctivates NF-kB and induces vascular adhesion molecule expression 2003
Structure of the O-specific polysaccharide of the Burkholderia brasiliensis 2003
Cloning and characterization of phosphoglucomutase (PGM) gene from Trypanosoma cruzi 2003
CLONING AND CHARACTERIZATION OF THE PHOSPHOGLUCOMUTASE (PGM) GENE FROM TRYPANOSOMA CRUZI. 2003
HOMOLOGS OF THE YEAST LONGEVITYASSURANCE GENE (LAG-1) IN TRYPANOSOMA CRUZI: UNRAVELING THE MECHANISMS OF CERAMIDE BIOSYNTHESIS 2003
PIPERINE AND ITS DERIVATES: POSSIBLE MECHANISMS OF ACTION AGAINST TRYPANOSOMA CRUZI. A COMPARATIVE STUDY INVOLVING CHEMICAL STRUCTURE AND BIOLOGICAL ACTIVITY 2003
INHIBITION OF THE OUABAIN-INSENSITIVE NA+-ATPASE ACTIVITY FROM EPIMASTIGOTES OF TRYPANOSOMA CRUZI BY MILTEFOSINE 2003
PARTIAL CHARACTERIZATION OF A UDPGLCNAC: POLYPEPTIDE A-NACETYLGLUCOSAMINYLTRANSFERASE IN CRITHIDIA FASCICULATA. 2003
THE TOXIC EFFECTS AND POSSIBLE MECHANISMS OF ACTION OF HEXADECYLPHOSPHOCHOLINE (MILTEFOSINE) AGAINST TRYPANOSOMA CRUZI: STUDIES IN VITRO AND IN VIVO 2003
Partial characterization of the Trypanosoma cruzi inositolphosphorylceramide (IPC) synthase. 2002
Chemical investigation of the novel carbohydrate of the lipopolysaccharide from Burkholderia brasiliensis. 2002
Structural characterization of glycoinositolphosphorylceramides from mycelium forms of different strains of Sporothrix schenckii. 2002
Acceptor specificity of beta-galactofuranosyltransferase involved in the biosynthesis of GIPLs of Trypanosoma cruzi Y-strain. 2002
Brasiliose: a novel 4-C-branched sugar of lipopolysaccharides from the diazotrophic endophytic bacterium Burkholderia brasiliensis 2002
Antiproliferative action of hexadecylphosphocholine (Miltefosine) against intracellular amastigote forms of Trypanosoma cruzi 2002
Antiproliferative effects of the fungicidal agent aureobasidin A against Trypanosoma cruzi 2002
Effects of the natural alkaloid piperine on Trypanosoma cruzi: cytotoxicity and possible mechanism of action 2002
Sphingolipid biosynthetic pathway in Trypanosoma cruzi: potential target for chemotherapy against Chagas'disease 2001
Structure of lipolysaccharides synthesized by the diazotrophic bacterium Burkholderia brasiliensis 2001
Mannosylinositolphosphorylceramide from Sporothrix schenckii 2001
Síntese de substratos e potenciais inibidores de enzimas envolvidas na biossíntese de éter-lipídeos em Trypanosoma cruzi 2001
Preliminary characterization of the carbohydrate group antigen from a clinical isolate of Streptococcus dysgalactiae belonging to Lancefield's serogroup A 2001
Structural analysis of an exopolysaccharide (EPS B) produced by Burkholderia brasiliensis an endophytic nitrogen-fixing bacterium 2001
Studies on glycan structures of glycoproteins and glycolipids of Trypanosoma cruzi 2001
The inositol phosphorylceramide synthase of Trypanosoma cruzi 2001
Biosynthesis of O-linked oligosaccharides of the Trypanosoma cruzi sialoglycoprotein: characterization of beta-1,4-galactopyranosyltransferase activity 2001
Cytotoxic activity of Miltefosine against Trypanosoma cruzi: studies in vitro and in vivo 2001
Characterization of the Trypanosoma cruzi inositol phosphorylceramide synthase 2001
Characterization of a specific beta-galactopyranosyltransferase activity involved in the biosynthesis of O-linked oligosaccharides of the Trypanosoma cruzi mucin-like molecules 2001
Síntese de Substratos e Potenciais Inibidores de Enzimas Envolvidas na Biossíntese de Éter-Lipídeos em Trypanosoma cruzy 2001
Studies on glycan structures of glycoproteins and glycolipids of Trypanosoma cruzi 2001
The inositol phosphorylceramide synthase of Trypanosoma cruzi 2001
Inhibitors of sphingolipid biosynthesis and their effects against Trypanosoma cruzi 2000
A novel family of glycophosphosphingolipids expressed by yeast forms of Sporothrix schenckii: evidence for a unique Manalfa1-6Inositol-phosphorylceramide 2000
Analysis of O-linked N-acetylglucosamine-containing oligosaccharides from sialic acid acceptor glycoproteins expressed by trypomastigote forms of Trypanosoma cruzi 2000
Partial characterization and sub-cellular localisation of the palmitoyl-CoA reductase from Phytomonas sp. 2000
Substrate specificity of beta-galactosyltransferase (beta GalT) of Trypanosoma cruzi 2000
Chemical synthesis of dihydroxyacetonephosphate pathway substrates for studies of the ether-lipid biosynthesis in Trypanosoma cruzi 2000
A novel family of glycophosphosphingolipid expressed by yeast forms of Sporothrix schenckii: evidence for a unique man-alfa1-6Ins-phosphorylceramide substructure. 2000
Analysis of O-linked N-acetylglucosamine-containing oligosaccharides from sialic acid-acceptor glycoproteins expressed by trypomastigote forms of Trypanosoma cruzi (Colombiana strain) 2000
Characterization of a new acidic exopolysaccharide produced by Burkholderia brasiliensis strain M130. 2000
Inhibitors of sphingolipid biosynthesis and their effects on Trypanosoma cruzi growth in an axenic culture 2000
Efeito de novas drogas antifúngicas sobre a biossíntese de esfingolipídeos em Trypanosoma cruzi. 2000
Inhibitors of sphingolipid biosynthesis and their effects against Trypanosoma cruzi 2000
Partial characterisation and sub-cellular localisation of the palmitoyl-CoA reductase from Phytomonas sp. 2000
Chemical synthesis of the dihydroxyacetonephosphate pathway substrates for studies of the ether-lipid biosynthesis in Trypanosoma cruzi 2000
Partial characterization and subcellular localization of the palmitoyl-coa reductase from Phytomonas sp. 2000
Substrate specificity of B-galactosyltransferase (BGALT) of Trypanosoma cruzi 2000
Subcellular localisation of a major soluble HMG-CoA reductase in mitochondrial matrix of Trypanosoma brucei procyclics 1999
Partial purification of O-alpha-N-acetylglucosaminyltransferase of Trypanosoma cruzi Y-strain 1999
Partial molecular structure of GIPLs of Trypanosoma cruzi Colombiana strain 1999
Acidic exopolysaccharide from Burkholderia brasiliensis, an endophytic nitrogen fixing bacterium 1999
Molecular structure of a new glycosphingolipid (GPS) isolated from Cryptococcus neoformans 1999
Structure of the acidic exopolysaccharide (EPS) produced by Burkholderia brasiliensis, an endophytic nitrogen-fixing bacterium 1999
Ether lipids X ceramides in GPI anchors of trypanosomatidae: first round 1999
Further purification and localization of O-alpha-N-acetylglucosaminyl transferase of Trypanosoma cruzi Y-strain 1999
Chemical synthesis of long-chain fatty alcohols, 1-O-alkyl and 1-o-acyl-dihydroxyacetone-3-phosphate and their analogues for studies of the ether-lipid biosynthesis in Trypanosoma cruzi 1999
Effects of fungal sphingolipid biosynthetic pathway inhibitors over Trypanosoma cruzi in axenic culture 1999
Tandem nan-electrospray analyses of O-linked-N-acetyl glucosamine-containing oligosaccharides from sialic acid acceptor glycoproteins of trypomastigote forms of Trypanosoma cruzi (Colombiana strain) 1999
Molecular structure of new glycophosphosphingolipids isolated from Cryptococcus neoformans 1999
Molecular Structure of new glycophosphosphingolipids isolated from Cryptococcus neoformans 1999
Ether lipids X Ceramides in GPI anchors of Trypanosomatids: First Round 1999
Tandem nano-electrospray analyses of O-linked-N-acetyl glucosamine containing oligosaccharides from sialic acid acceptor glycoproteins of trypomastigote forms of Trypanosoma cruzi (Colombiana strain) 1999
Subcellular localisation of a major soluble HMG-CoA Reductase in the mitochondrial matrix of Trypanosoma brucei procyclics 1999
Partial purification of O-alpha-N-acetylglucosaminyl transferase of Trypanosoma cruzi Y-strain 1999
Partial molecular structure of glycoinositolphospholipids of Trypanosoma cruzi Colombiana strain 1999
Molecular structure of a new glycosphingolipid isolated from Cryptococcus neoformans 1999
Purification, Characterisation And Sub-Cellular Localisation Of Glucose-6-Phosphate Dehydrogenase From Trypanosoma Brucei Procyclic Forms 1998
Glycoinositolphospholipids (Gipls) Of Trypanosoma Cruzi Colombiana Strain 1998
Characterization Of Alpha-N-Acetylglucosaminyl Transferase Activity In Different Strains Of Trypanosoma Cruzi 1998
Partial Characterisation Of Dihydroxyacetonephosphate Acyl-Transferase Of Leishmania Mexicana Promastigotes 1998
New enzymes and pathways in the Trypanosomatidae 1998
Purification characterization and sub-cellular localization of glucose-6-phosphate dehydrogenase from Trypanosoma brucei procyclic forms. 1998
Partial characterization of dihydroxyacetonephosphate acyl-transferase of Leishmania mexicana promastigotes. 1998
GIPLS of Trypanosoma cruzi colombiana strain. 1998
Glycoinositolphospholipids (GIPLS) of Trypanosoma cruzi Colombiana strain. 1998
Caracterizaçao de um novo glicoesfingolipídeo em Cryptococcus neoformans. 1998
Ocorrência natural de um novo glicofosfoesfingolipídeo em C. neoformans. 1998
Characterization of alfa-N-acetylglucosaminyl transferase activity in different strains of T. cruzi 1998
New enzymes and pathways in the Trypanosomatidae 1998
Characterization of alfa-N-acetylglucosaminyl transferase activity in different strains of Trypanosoma cruzi. 1998
Characterisation And Sub-Cellular Localisation Of Glucose-6-Phosphate Dehydrogenase From Trypanosoma Brucei Procyclic Forms 1997
The Ether-Lipid Biosynthesis In Leishmania Mexicana Promastigotes 1996
Gpi Protein Anchors Of Trypanosoma Cruzi Are Synthesized As Two Complete Precursors 1996
Chasing The Precurssors For The Gpi Anchors From Trypanosoma Cruzi 1995
Identification Of A Candidate Precursor For The Gpi Protein Anchor In Insect Forms Of Trypanosoma Cruzi 1994
Characterization Of A Putative Candidate For The Gpi Protein Anchor In Trypanosoma Cruzi 1994
Glycosylphosphatidylinositol Membrane Anchors In Trypanosoma Cruzi 1993
Characterization Of The Lipid Composition Of The Glycosylphosphatidylinositol Anchor Of The Trypanosoma Cruzi 1g7-Antigen 1993
Gpi Anchors In Surface Antigens Of Trypanosoma Cruzi 1992
Muci-Like Glycoproteins Linked To The Membrane By Gpi Anchor Are The Major Acceptor Of Sialic Acid In A Reaction Catalysed By Trans-Sialidase In Metacyclic Forms Of Trypanosoma Cruzi 1992
Morphological, Histochemical And Biochemical Studies On A Case Of Congenital Generalized Fibromatosis 1992
Heterogeneity Among The 90kda Population Of The Major Surface Antigen Of Trypanosoma Cruzi Metacyclic Trypomastigotes 1991
Puzzling behaviour of in vitro phospholipase solubilization of the GPI anchor of the 1G7-Ag of Trypanosoma cruzi 1991
GPI anchors in Trypanosoma cruzi 1990
GPI membrane anchors and differentiation of epimastigotes into metacyclic trypomastigotes in axenic cultures 1989
Age-related changes of glycosaminoglycans from normal rabbit hyaline cartilage 1989
Different Populations of knee-joint menisci proteoglycans produced by exhaustive extraction 1988
Age-related changes of glycosaminoglycans from normal rabbit costal cartilage 1988
Glycosaminoglycan distribution in anatomically distinct sites of the articular cartilage 1988
Glycosaminoglycans from synovial fluid of juvenile rheumatoid arthritis (JRA) 1985
Publicações:
Minha Rede: