Antonio Galina Filho
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Bioquímica Médica
Departamento:
Programa de Biologia Celular e Biofisica
Formação:
-
Universidade Federal do Rio de Janeiro
Química Biológica | Doutorado | 1991 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:
(89.11% artigos com DOI)
Titulo | DOI | Ano |
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The NADase CD38 May not dictate NAD levels in brain Mitochondria of aged mice but regulates hydrogen peroxide generation | 10.1016/j.freeradbiomed.2023.09.035 | 2023 |
Bone Marrow Mononuclear Cells Restore Normal Mitochondrial Ca2+ Handling and Ca2+-Induced Depolarization of the Internal Mitochondrial Membrane by Inhibiting the Permeability Transition Pore After Ischemia/Reperfusion. | 10.1177/09636897221085883. | 2022 |
Coupling of GABA Metabolism to Mitochondrial Glucose Phosphorylation | 10.1007/s11064-021-03463-2. | 2022 |
Physical exercise improves mitochondrial function in ovariectomized rats | 10.1530/joe-22-0057 | 2022 |
3-Bromopyruvate: A new strategy for inhibition of glycolytic enzymes in Leishmania amazonensis | 10.1016/j.exppara.2021.108154 | 2021 |
Mitotherapy: Unraveling a Promising Treatment for Disorders of the Central Nervous System and Other Systemic Conditions | 10.3390/cells10071827 | 2021 |
Mortality of septic shock patients is associated with impaired mitochondrial oxidative coupling efficiency in lymphocytes: a prospective cohort study | 10.1186/s40635-021-00404-9 | 2021 |
Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema | 10.3389/fcell.2021.661385 | 2021 |
Dopamine signaling impairs ROS modulation by mitochondrial hexokinase in human neural progenitor cells | 10.1042/BSR20211191. | 2021 |
The yeast protein Ubx4p contributes to mitochondrial respiration and lithium-galactose-mediated activation of the unfolded protein response | 10.1074/jbc.ra119.011271 | 2020 |
Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes. | 10.1038/s41598-020-57914-x. | 2020 |
Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. | 10.1016/j.bbadis.2020.165686. | 2020 |
Energization by multiple substrates and calcium challenge reveal dysfunctions in brain mitochondria in a model related to acute psychosis. | 10.1007/s10863-019-09816-5. | 2020 |
NOD Mice Recapitulate the Cardiac Disturbances Observed in Type 1 Diabetes | 10.1007/s12265-020-10039-y | 2020 |
Acute Myocardial Infarction Reduces Respiration in Rat Cardiac Fibers, despite Adipose Tissue Mesenchymal Stromal Cell Transplant | 10.1155/2020/4327965 | 2020 |
Guanosine Neuroprotection of Presynaptic Mitochondrial Calcium Homeostasis in a Mouse Study with Amyloid-β Oligomers | 10.1007/s12035-020-02064-4 | 2020 |
Type 2 diabetes mellitus alters cardiac mitochondrial content and function in a non-obese mice model | 10.1590/0001-3765202020191340 | 2020 |
A Protocol to Study Mitochondrial Function in Human Neural Progenitors and iPSC-Derived Astrocytes | 10.1002/cptx.97 | 2020 |
Hyperglycemia in a type 1 Diabetes Mellitus model causes a shift in mitochondria coupled-glucose phosphorylation and redox metabolism in rat brain | 10.1016/j.freeradbiomed.2020.09.017 | 2020 |
Mitochondrial pyruvate carrier as a key regulator of fever and neuroinflammation | 10.1016/j.bbi.2020.11.031 | 2020 |
Mitochondrial physiology | 10.26124/bec:2020-0001.v1 | 2020 |
Inhibition of energy metabolism by 3-bromopyruvate in the hard tick Rhipicephalus microplus | 10.1016/j.cbpc.2018.12.010 | 2019 |
Glutamine Therapy Reduces Inflammation and Extracellular Trap Release in Experimental Acute Respiratory Distress Syndrome of Pulmonary Origin. | 10.3390/nu11040831. | 2019 |
Mitochondria-coupled glucose phosphorylation develops after birth to modulate H 2 O 2 release and calcium handling in rat brain | 10.1111/jnc.14705 | 2019 |
Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice | 10.1113/ep087317 | 2019 |
Extracellular vesicles derived from human Wharton?s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers | 10.1186/s13287-019-1432-5. | 2019 |
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers | 10.1074/jbc.m117.807180 | 2018 |
Rapid regulation of substrate use for oxidative phosphorylation during a single session of high intensity interval or aerobic exercises in different rat skeletal muscles | 10.1016/j.cbpb.2017.11.013 | 2018 |
Intense physical exercise potentiates glucose inhibitory effect over food intake of male Wistar rats | 10.1113/ep086916 | 2018 |
The synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations includes hexokinase activity and mitochondrial efficiency | 10.1371/journal.pone.0202784 | 2018 |
Perinatal Asphyxia and Brain Development: Mitochondrial Damage Without Anatomical or Cellular Losses | 10.1007/s12035-018-1019-7 | 2018 |
Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria | 10.1074/jbc.m117.786582 | 2017 |
Mitochondria-Bound Hexokinase (mt-HK) Activity Differ in Cortical and Hypothalamic Synaptosomes: Differential Role of mt-HK in H2O2 Depuration | 10.1007/s12035-017-0807-9 | 2017 |
The Symbiotic Bacterium Fuels the Energy Metabolism of the Host Trypanosomatid Strigomonas culicis | 10.1016/j.protis.2017.02.001 | 2017 |
Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice | 10.1017/s0007114517001817 | 2017 |
Enhanced OXPHOS, glutaminolysis and -oxidation constitute the metastatic phenotype of melanoma cells | 10.1042/bj20150645 | 2016 |
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism | 10.1016/j.cmet.2016.05.006 | 2016 |
Direct electric current treatment modifies mitochondrial function and lipid body content in the A549 cancer cell line | 10.1016/j.bioelechem.2016.05.004 | 2016 |
Succinate dehydrogenase (mitochondrial complex II) is a source of reactive oxygen species in plants and regulates development and stress responses | 10.1111/nph.13515 | 2015 |
High Intensity Interval Training (HIIT) Induces Specific Changes in Respiration and Electron Leakage in the Mitochondria of Different Rat Skeletal Muscles | 10.1371/journal.pone.0131766 | 2015 |
Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells | 10.7717/peerj.1486 | 2015 |
Valproate Disturbs Morphology and Mitochondrial Membrane Potential in Human Neural Cells | 10.1089/aivt.2015.0016 | 2015 |
Role of Estrogen on Skeletal Muscle Mitochondrial Function in Ovariectomized Rats: A Time Course Study in Different Fiber Types | 10.1152/japplphysiol.00121.2013 | 2014 |
Mitochondria: 3-bromopyruvate vs. mitochondria? A small molecule that attacks tumors by targeting their bioenergetic diversity | 10.1016/j.biocel.2014.05.013 | 2014 |
Diphenyl diselenide protects endothelial cells against oxidized low density lipoprotein-induced injury: involvement of mitochondrial function | 10.1016/j.biochi.2014.07.004 | 2014 |
The Impact of Stem Cells on Electron Fluxes, Proton Translocation, and ATP Synthesis in Kidney Mitochondria After Ischemia/Reperfusion | 10.3727/096368912x659862 | 2014 |
Type 2 iodothyronine deiodinase is upregulated in rat slow- and fast-twitch skeletal muscle during cold exposure | 10.1152/ajpendo.00637.2013 | 2014 |
Unveiling the effects of berenil, a DNA-binding drug, on Trypanosoma cruzi: implications for kDNA ultrastructure and replication | 10.1007/s00436-014-4199-8 | 2014 |
Mitochondrial respiration and genomic analysis provide insight into the influence of the symbiotic bacterium on host trypanosomatid oxygen consumption | 10.1017/s0031182014001139 | 2014 |
Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle | 10.1242/bio.20122295 | 2013 |
Nitric oxide inhibits succinate dehydrogenase-driven oxygen consumption in potato tuber mitochondria in an oxygen tension-independent manner | 10.1042/BJ20120396 | 2013 |
2,4-dinitrophenol induces neural differentiation of murine embryonic stem cells | 10.1016/j.scr.2013.09.016 | 2013 |
How does the metabolism of tumour cells differ from that of normal cells | 10.1042/BSR20130066 | 2013 |
Insulin prevents mitochondrial generation of H2O2 in rat brain | 10.1016/j.expneurol.2013.03.007 | 2013 |
Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase | 10.1007/s10863-012-9413-8 | 2012 |
3-Bromopyruvate inhibits calcium uptake by sarcoplasmic reticulum vesicles but not SERCA ATP hydrolysis activity | 10.1016/j.biocel.2012.02.002 | 2012 |
Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases | 2012 | |
Physical exercise exacerbates memory deficits induced by intracerebroventricular STZ but improves insulin regulation of H₂O₂ production in mice synaptosomes | 10.3233/JAD-2012-112066 | 2012 |
Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders | 10.1016/j.abb.2012.10.009 | 2012 |
Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced F1Fo adenosine-5?-triphosphate synthase activity* | 10.1097/CCM.0b013e31820eda5c | 2011 |
Energy Metabolism in H460 Lung Cancer Cells: Effects of Histone Deacetylase Inhibitors | 10.1371/journal.pone.0022264 | 2011 |
Brown adipose tissue mitochondria: modulation by GDP and fatty acids depends on the respiratory substrates | 10.1042/BSR20100144 | 2011 |
Antioxidant activity of natural compounds of Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae, by scavenger of mitochondrial reactive oxygen species | 10.1590/S0102-695X2011005000050 | 2011 |
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient | 10.3727/096368911x600957 | 2011 |
Dynamics of human hepatic cells metabolome during dengue virus infection | 2011 | |
Expression Profile of Rat Hippocampal Neurons Treated with the Neuroprotective Compound 2,4-Dinitrophenol: Up-Regulation of cAMP Signaling Genes | 10.1007/s12640-009-9133-y | 2010 |
Characterization of the non-cytosolic hexokinase activity in the white skeletal muscle from goldfish (Carassius auratus L.) and effect of cold acclimation | 10.1042/BSR20090128 | 2010 |
Mitochondrial Dysfunction Induced by Different Organochalchogens is Mediated by Thiols Oxidation and is not Dependent of the Classical Mitochondrial Permeability Transition Pore Opening | 10.1093/toxsci/kfq185 | 2010 |
Amyloid-? Triggers the Release of Neuronal Hexokinase 1 from Mitochondria | 10.1371/journal.pone.0015230 | 2010 |
REACTIVE OXYGEN SPECIES PRODUCTION BY POTATO TUBER MITOCHONDRIA IS MODULATED BY MITOCHONDRIALLY BOUND HEXOKINASE ACTIVITY | 10.1104/pp.108.129247 | 2009 |
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate | 10.1042/BJ20080805 | 2009 |
Blood-Feeding Induces Reversible Functional Changes in Flight Muscle Mitochondria of Aedes aegypti Mosquito | 10.1371/journal.pone.0007854 | 2009 |
Modulation of Trypanosoma rangeli ecto-phosphatase activity by hydrogen peroxide | 10.1016/j.freeradbiomed.2009.04.020 | 2009 |
Hepatic glycogen synthesis in the absence of GK. The case of embryonic liver. | 10.1074/jbc.M706334200 | 2008 |
Sepsis induces brain mitochondrial dysfunction | 10.1097/CCM.0b013e3181760c4b | 2008 |
Reactive oxygen species generation is modulated by mitochondrial kinases: correlation with mitochondrial antioxidant peroxidases in rat tissues | 10.1016/j.biochi.2008.06.013 | 2008 |
Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and Ca2+ ATPase (SERCA 1) heat production | 10.1210/en.2008-0564 | 2008 |
S12.16 mitochondrial dysfunction in neuroblastoma cells infected with sindbis virus | 10.1016/j.bbabio.2008.05.311 | 2008 |
Glucose metabolism during embryogenesis of the hard tick Boophilus microplus | 10.1016/j.cbpa.2006.05.009 | 2007 |
Mitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virus | 10.1016/j.bbadis.2007.08.003 | 2007 |
Partial purification of tightly bound mitochondrial hexokinase from maize (Zea mays L.) ROOT membranes. | 2006 | |
MITOCHONDRIAL CREATINE KINASE ACTIVITY PREVENTS REACTIVE OXYGEN SPECIES GENERATION: Antioxidant role of mitochondrial kinases-dependent ADP re-cycling activity | 10.1074/jbc.M604123200 | 2006 |
Antioxidant role of mitochondrial bound hexokinase | 2005 | |
Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense: Steady State ADP Formation as a Regulatory Mechanism of Membrane Potential and Reactive Oxygen Species Generation in Mitochondria | 10.1074/jbc.m403835200 | 2004 |
Heat of PPi hydrolysis Varies Depending on the Enzyme Used. Yeast PPase and Corn Vacuolar PPase | 10.1074/jbc.m408866200 | 2004 |
Proton Transport in Maize Tonoplasts Supported by Fructose-1,6-Bisphosphate Cleavage. Pyrophosphate Dependent Phosphofructokinase as a Pyrophosphate-regenerating system | 10.1104/pp.103.026633 | 2003 |
Maize Tonoplast PPi-Dependent H+/Ca2+ Exchange: Two Ks For Ca2+ and Inhibition by Thapsigargin | 10.1016/s0006-291x(03)01226-9 | 2003 |
Phosphoglucomutase is an in vivo lithium target in yeast | 10.1074/jbc.m101451200 | 2001 |
Subcellular distribution and kinetic properties of cytosolic and non-cytosolic hexokinases in maize seedling roots: Implications for hexose phosphorylation | 2001 | |
Hexokinase activity alters sugar-nucleotide formation in maize root homogenates. | 10.1016/s0031-9422(99)00456-2 | 2000 |
Sarcoplasmic reticulum Ca(2+)-ATPase of sea cucumber smooth muscle: regulation by K(+) and ATP | 10.1016/s1095-6433(00)00197-5 | 2000 |
Catalytic activity and heat production by the Ca(2+)-ATPase from sea cucumber (Ludwigothureagrisea) longitudinal smooth muscle: modulation by monovalent cations | 2000 | |
Sugar phosphorylation modulates ADP inhibition of maize mitochondrial hexokinase. | 10.1034/j.1399-3054.1999.105104.x | 1999 |
Molecular characterisation of a NADH ubiquinone oxidoredutase subunit 5 from Schistosoma mansoni and inhibition of mitochondrial respiratory chain function by testosterone. | 10.1023/a:1007057903390 | 1999 |
Water requirements in monomer folding and dimerization of triosephosphate isomerase in reverse micelles. Intrinsic fluorescence of conformers related to reactivation. | 10.1021/bi00001a044 | 1995 |
Different properties of the mitochondrial and citosolic hexokinases in maize roots. | 1995 | |
Biochemical Education: A stractegy to introduce young students to biochemical research. | 1995 | |
Reversal of oxidative phosphorylation in submitochondrial particles using glucose 6-phosphate and hexokinase as an ATP regenerating systems. | 10.1016/0014-5793(92)81273-o | 1992 |
The maxwell Demon in Biological Systems: Use of Glucose 6-phosphate and Hexokinase as an ATP regenerating system by the Ca2+-ATPase of sarcoplasmic reticulum and submitochondrial particles. | 1992 | |
Correlation between Ca2+ uptake, Ca2+ efflux and phosphoenzyme level in sarcoplasmic reticulum vesicles. | 1991 | |
Ca2+ translocation and catalitic activity of the sarcoplasmic reticulum ATPase: Modulation by ATP, Ca2+ and Pi. | 1991 |
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