Antonio Galina Filho

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Biologia Celular e Biofisica

ORCID:

não disponível no Lattes


Formação:
  • Universidade Federal do Rio de Janeiro

    Química Biológica | Doutorado | 1991 - 1994
Laboratórios:
Nuvens de Palavras:
Artigos:

(89.11% artigos com DOI)

Titulo DOI Ano
The NADase CD38 May not dictate NAD levels in brain Mitochondria of aged mice but regulates hydrogen peroxide generation 10.1016/j.freeradbiomed.2023.09.035 2023
Bone Marrow Mononuclear Cells Restore Normal Mitochondrial Ca2+ Handling and Ca2+-Induced Depolarization of the Internal Mitochondrial Membrane by Inhibiting the Permeability Transition Pore After Ischemia/Reperfusion. 10.1177/09636897221085883. 2022
Coupling of GABA Metabolism to Mitochondrial Glucose Phosphorylation 10.1007/s11064-021-03463-2. 2022
Physical exercise improves mitochondrial function in ovariectomized rats 10.1530/joe-22-0057 2022
3-Bromopyruvate: A new strategy for inhibition of glycolytic enzymes in Leishmania amazonensis 10.1016/j.exppara.2021.108154 2021
Mitotherapy: Unraveling a Promising Treatment for Disorders of the Central Nervous System and Other Systemic Conditions 10.3390/cells10071827 2021
Mortality of septic shock patients is associated with impaired mitochondrial oxidative coupling efficiency in lymphocytes: a prospective cohort study 10.1186/s40635-021-00404-9 2021
Mesenchymal Stromal Cells From Emphysematous Donors and Their Extracellular Vesicles Are Unable to Reverse Cardiorespiratory Dysfunction in Experimental Severe Emphysema 10.3389/fcell.2021.661385 2021
Dopamine signaling impairs ROS modulation by mitochondrial hexokinase in human neural progenitor cells 10.1042/BSR20211191. 2021
The yeast protein Ubx4p contributes to mitochondrial respiration and lithium-galactose-mediated activation of the unfolded protein response 10.1074/jbc.ra119.011271 2020
Zika virus infection leads to mitochondrial failure, oxidative stress and DNA damage in human iPSC-derived astrocytes. 10.1038/s41598-020-57914-x. 2020
Neuroprotection from optic nerve injury and modulation of oxidative metabolism by transplantation of active mitochondria to the retina. 10.1016/j.bbadis.2020.165686. 2020
Energization by multiple substrates and calcium challenge reveal dysfunctions in brain mitochondria in a model related to acute psychosis. 10.1007/s10863-019-09816-5. 2020
NOD Mice Recapitulate the Cardiac Disturbances Observed in Type 1 Diabetes 10.1007/s12265-020-10039-y 2020
Acute Myocardial Infarction Reduces Respiration in Rat Cardiac Fibers, despite Adipose Tissue Mesenchymal Stromal Cell Transplant 10.1155/2020/4327965 2020
Guanosine Neuroprotection of Presynaptic Mitochondrial Calcium Homeostasis in a Mouse Study with Amyloid-β Oligomers 10.1007/s12035-020-02064-4 2020
Type 2 diabetes mellitus alters cardiac mitochondrial content and function in a non-obese mice model 10.1590/0001-3765202020191340 2020
A Protocol to Study Mitochondrial Function in Human Neural Progenitors and iPSC-Derived Astrocytes 10.1002/cptx.97 2020
Hyperglycemia in a type 1 Diabetes Mellitus model causes a shift in mitochondria coupled-glucose phosphorylation and redox metabolism in rat brain 10.1016/j.freeradbiomed.2020.09.017 2020
Mitochondrial pyruvate carrier as a key regulator of fever and neuroinflammation 10.1016/j.bbi.2020.11.031 2020
Mitochondrial physiology 10.26124/bec:2020-0001.v1 2020
Inhibition of energy metabolism by 3-bromopyruvate in the hard tick Rhipicephalus microplus 10.1016/j.cbpc.2018.12.010 2019
Glutamine Therapy Reduces Inflammation and Extracellular Trap Release in Experimental Acute Respiratory Distress Syndrome of Pulmonary Origin. 10.3390/nu11040831. 2019
Mitochondria-coupled glucose phosphorylation develops after birth to modulate H 2 O 2 release and calcium handling in rat brain 10.1111/jnc.14705 2019
Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice 10.1113/ep087317 2019
Extracellular vesicles derived from human Wharton?s jelly mesenchymal stem cells protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers 10.1186/s13287-019-1432-5. 2019
Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers 10.1074/jbc.m117.807180 2018
Rapid regulation of substrate use for oxidative phosphorylation during a single session of high intensity interval or aerobic exercises in different rat skeletal muscles 10.1016/j.cbpb.2017.11.013 2018
Intense physical exercise potentiates glucose inhibitory effect over food intake of male Wistar rats 10.1113/ep086916 2018
The synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations includes hexokinase activity and mitochondrial efficiency 10.1371/journal.pone.0202784 2018
Perinatal Asphyxia and Brain Development: Mitochondrial Damage Without Anatomical or Cellular Losses 10.1007/s12035-018-1019-7 2018
Short-term starvation is a strategy to unravel the cellular capacity of oxidizing specific exogenous/endogenous substrates in mitochondria 10.1074/jbc.m117.786582 2017
Mitochondria-Bound Hexokinase (mt-HK) Activity Differ in Cortical and Hypothalamic Synaptosomes: Differential Role of mt-HK in H2O2 Depuration 10.1007/s12035-017-0807-9 2017
The Symbiotic Bacterium Fuels the Energy Metabolism of the Host Trypanosomatid Strigomonas culicis 10.1016/j.protis.2017.02.001 2017
Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice 10.1017/s0007114517001817 2017
Enhanced OXPHOS, glutaminolysis and  -oxidation constitute the metastatic phenotype of melanoma cells 10.1042/bj20150645 2016
CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism 10.1016/j.cmet.2016.05.006 2016
Direct electric current treatment modifies mitochondrial function and lipid body content in the A549 cancer cell line 10.1016/j.bioelechem.2016.05.004 2016
Succinate dehydrogenase (mitochondrial complex II) is a source of reactive oxygen species in plants and regulates development and stress responses 10.1111/nph.13515 2015
High Intensity Interval Training (HIIT) Induces Specific Changes in Respiration and Electron Leakage in the Mitochondria of Different Rat Skeletal Muscles 10.1371/journal.pone.0131766 2015
Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells 10.7717/peerj.1486 2015
Valproate Disturbs Morphology and Mitochondrial Membrane Potential in Human Neural Cells 10.1089/aivt.2015.0016 2015
Role of Estrogen on Skeletal Muscle Mitochondrial Function in Ovariectomized Rats: A Time Course Study in Different Fiber Types 10.1152/japplphysiol.00121.2013 2014
Mitochondria: 3-bromopyruvate vs. mitochondria? A small molecule that attacks tumors by targeting their bioenergetic diversity 10.1016/j.biocel.2014.05.013 2014
Diphenyl diselenide protects endothelial cells against oxidized low density lipoprotein-induced injury: involvement of mitochondrial function 10.1016/j.biochi.2014.07.004 2014
The Impact of Stem Cells on Electron Fluxes, Proton Translocation, and ATP Synthesis in Kidney Mitochondria After Ischemia/Reperfusion 10.3727/096368912x659862 2014
Type 2 iodothyronine deiodinase is upregulated in rat slow- and fast-twitch skeletal muscle during cold exposure 10.1152/ajpendo.00637.2013 2014
Unveiling the effects of berenil, a DNA-binding drug, on Trypanosoma cruzi: implications for kDNA ultrastructure and replication 10.1007/s00436-014-4199-8 2014
Mitochondrial respiration and genomic analysis provide insight into the influence of the symbiotic bacterium on host trypanosomatid oxygen consumption 10.1017/s0031182014001139 2014
Cold acclimation increases mitochondrial oxidative capacity without inducing mitochondrial uncoupling in goldfish white skeletal muscle 10.1242/bio.20122295 2013
Nitric oxide inhibits succinate dehydrogenase-driven oxygen consumption in potato tuber mitochondria in an oxygen tension-independent manner 10.1042/BJ20120396 2013
2,4-dinitrophenol induces neural differentiation of murine embryonic stem cells 10.1016/j.scr.2013.09.016 2013
How does the metabolism of tumour cells differ from that of normal cells 10.1042/BSR20130066 2013
Insulin prevents mitochondrial generation of H2O2 in rat brain 10.1016/j.expneurol.2013.03.007 2013
Effect of the antitumoral alkylating agent 3-bromopyruvate on mitochondrial respiration: role of mitochondrially bound hexokinase 10.1007/s10863-012-9413-8 2012
3-Bromopyruvate inhibits calcium uptake by sarcoplasmic reticulum vesicles but not SERCA ATP hydrolysis activity 10.1016/j.biocel.2012.02.002 2012
Cardiac systolic dysfunction in doxorubicin-challenged rats is associated with upregulation of MuRF2 and MuRF3 E3 ligases 2012
Physical exercise exacerbates memory deficits induced by intracerebroventricular STZ but improves insulin regulation of H₂O₂ production in mice synaptosomes 10.3233/JAD-2012-112066 2012
Pluripotent stem cells as a model to study oxygen metabolism in neurogenesis and neurodevelopmental disorders 10.1016/j.abb.2012.10.009 2012
Bioenergetic failure of human peripheral blood monocytes in patients with septic shock is mediated by reduced F1Fo adenosine-5?-triphosphate synthase activity* 10.1097/CCM.0b013e31820eda5c 2011
Energy Metabolism in H460 Lung Cancer Cells: Effects of Histone Deacetylase Inhibitors 10.1371/journal.pone.0022264 2011
Brown adipose tissue mitochondria: modulation by GDP and fatty acids depends on the respiratory substrates 10.1042/BSR20100144 2011
Antioxidant activity of natural compounds of Stachytarpheta cayennensis (Rich.) Vahl, Verbenaceae, by scavenger of mitochondrial reactive oxygen species 10.1590/S0102-695X2011005000050 2011
Altered oxygen metabolism associated to neurogenesis of induced pluripotent stem cells derived from a schizophrenic patient 10.3727/096368911x600957 2011
Dynamics of human hepatic cells metabolome during dengue virus infection 2011
Expression Profile of Rat Hippocampal Neurons Treated with the Neuroprotective Compound 2,4-Dinitrophenol: Up-Regulation of cAMP Signaling Genes 10.1007/s12640-009-9133-y 2010
Characterization of the non-cytosolic hexokinase activity in the white skeletal muscle from goldfish (Carassius auratus L.) and effect of cold acclimation 10.1042/BSR20090128 2010
Mitochondrial Dysfunction Induced by Different Organochalchogens is Mediated by Thiols Oxidation and is not Dependent of the Classical Mitochondrial Permeability Transition Pore Opening 10.1093/toxsci/kfq185 2010
Amyloid-? Triggers the Release of Neuronal Hexokinase 1 from Mitochondria 10.1371/journal.pone.0015230 2010
REACTIVE OXYGEN SPECIES PRODUCTION BY POTATO TUBER MITOCHONDRIA IS MODULATED BY MITOCHONDRIALLY BOUND HEXOKINASE ACTIVITY 10.1104/pp.108.129247 2009
Inhibition of energy-producing pathways of HepG2 cells by 3-bromopyruvate 10.1042/BJ20080805 2009
Blood-Feeding Induces Reversible Functional Changes in Flight Muscle Mitochondria of Aedes aegypti Mosquito 10.1371/journal.pone.0007854 2009
Modulation of Trypanosoma rangeli ecto-phosphatase activity by hydrogen peroxide 10.1016/j.freeradbiomed.2009.04.020 2009
Hepatic glycogen synthesis in the absence of GK. The case of embryonic liver. 10.1074/jbc.M706334200 2008
Sepsis induces brain mitochondrial dysfunction 10.1097/CCM.0b013e3181760c4b 2008
Reactive oxygen species generation is modulated by mitochondrial kinases: correlation with mitochondrial antioxidant peroxidases in rat tissues 10.1016/j.biochi.2008.06.013 2008
Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and Ca2+ ATPase (SERCA 1) heat production 10.1210/en.2008-0564 2008
S12.16 mitochondrial dysfunction in neuroblastoma cells infected with sindbis virus 10.1016/j.bbabio.2008.05.311 2008
Glucose metabolism during embryogenesis of the hard tick Boophilus microplus 10.1016/j.cbpa.2006.05.009 2007
Mitochondrial and bioenergetic dysfunction in human hepatic cells infected with dengue 2 virus 10.1016/j.bbadis.2007.08.003 2007
Partial purification of tightly bound mitochondrial hexokinase from maize (Zea mays L.) ROOT membranes. 2006
MITOCHONDRIAL CREATINE KINASE ACTIVITY PREVENTS REACTIVE OXYGEN SPECIES GENERATION: Antioxidant role of mitochondrial kinases-dependent ADP re-cycling activity 10.1074/jbc.M604123200 2006
Antioxidant role of mitochondrial bound hexokinase 2005
Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense: Steady State ADP Formation as a Regulatory Mechanism of Membrane Potential and Reactive Oxygen Species Generation in Mitochondria 10.1074/jbc.m403835200 2004
Heat of PPi hydrolysis Varies Depending on the Enzyme Used. Yeast PPase and Corn Vacuolar PPase 10.1074/jbc.m408866200 2004
Proton Transport in Maize Tonoplasts Supported by Fructose-1,6-Bisphosphate Cleavage. Pyrophosphate Dependent Phosphofructokinase as a Pyrophosphate-regenerating system 10.1104/pp.103.026633 2003
Maize Tonoplast PPi-Dependent H+/Ca2+ Exchange: Two Ks For Ca2+ and Inhibition by Thapsigargin 10.1016/s0006-291x(03)01226-9 2003
Phosphoglucomutase is an in vivo lithium target in yeast 10.1074/jbc.m101451200 2001
Subcellular distribution and kinetic properties of cytosolic and non-cytosolic hexokinases in maize seedling roots: Implications for hexose phosphorylation 2001
Hexokinase activity alters sugar-nucleotide formation in maize root homogenates. 10.1016/s0031-9422(99)00456-2 2000
Sarcoplasmic reticulum Ca(2+)-ATPase of sea cucumber smooth muscle: regulation by K(+) and ATP 10.1016/s1095-6433(00)00197-5 2000
Catalytic activity and heat production by the Ca(2+)-ATPase from sea cucumber (Ludwigothureagrisea) longitudinal smooth muscle: modulation by monovalent cations 2000
Sugar phosphorylation modulates ADP inhibition of maize mitochondrial hexokinase. 10.1034/j.1399-3054.1999.105104.x 1999
Molecular characterisation of a NADH ubiquinone oxidoredutase subunit 5 from Schistosoma mansoni and inhibition of mitochondrial respiratory chain function by testosterone. 10.1023/a:1007057903390 1999
Water requirements in monomer folding and dimerization of triosephosphate isomerase in reverse micelles. Intrinsic fluorescence of conformers related to reactivation. 10.1021/bi00001a044 1995
Different properties of the mitochondrial and citosolic hexokinases in maize roots. 1995
Biochemical Education: A stractegy to introduce young students to biochemical research. 1995
Reversal of oxidative phosphorylation in submitochondrial particles using glucose 6-phosphate and hexokinase as an ATP regenerating systems. 10.1016/0014-5793(92)81273-o 1992
The maxwell Demon in Biological Systems: Use of Glucose 6-phosphate and Hexokinase as an ATP regenerating system by the Ca2+-ATPase of sarcoplasmic reticulum and submitochondrial particles. 1992
Correlation between Ca2+ uptake, Ca2+ efflux and phosphoenzyme level in sarcoplasmic reticulum vesicles. 1991
Ca2+ translocation and catalitic activity of the sarcoplasmic reticulum ATPase: Modulation by ATP, Ca2+ and Pi. 1991
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Abeta inhibits mitochondrial-bound hexokinase: Implications for impairment of brain energy metabolism in Alzheimer's disease 2005
Mitocondrial creatine kinase activity prevents reactive oxygen species generation: pivotal role of mitochondrial kinase ADP re-cycling as an antioxidant defense 2005
Antioxidant role of mitochondrial bound hexokinase 2004
Hexokinase as a Metabolic Target in the Hepatomas Treatment: Use 3-Bromopyruvate as a Inhbitor of Glucose Phosphorylation. Is the Main Action Mechanism? 2004
Glycolitic Enzymes associated to Rat Brain Synaptic Vesicles Control the ATP Synthesis for the V0V1-ATPase: Effect of therapeutic Hypothermia 2004
Fuctional Role of Mitochondrial Bound Hexokinase Activity: Steady State ADP Formation As A Regulatory Mechanism of Membrane Potencial and ROS Generation in Mitochondrial 2004
Functional Role of Mitochondrial Bound Hexokinase Activity: Steady State ADP Formation As A Regulatory Mechanism of Membrane Potencial in Mitochondria 2004
Ca2+ uptake in maize seedling roots (Zea mays L.) treated or not with CaCl2 2003
EFEITO DO EXERCÍCIO AERÓBIO PRÉVIO SOBRE A ATIVIDADE DA SDH E DA LDH NO MÚSCULO ESQUELÉTICO 2002
Ca2+ transport mediated by the H+/Ca2+ antiporter of maize root cells 2002
Interconversion of chemical and osmotic energy into heat by the pyrophosphatase of maize roots tonoplast 2002
Atividade da hexokinase em coleóptilos: modulação por hormônios de planta 2002
Effect of the fatty acids in the heat production by vacuolar H+-PP(i)ase of maize roots 2001
Hexokinase activities in maize coleoptiles: modulation by plant growth hormones. 2001
Distribution of fructokinases and hexokinases in maize (Zea mays L.): correlation with the hexose levels in plant tissues. 2001
Effect of the fatty acids in the heat production by vacuolar H+-PP(i)ase of maize roots 2001
Subcellular distribution and kinetic properties of cytosolic and non-cytosolic hexokinases in maize seedling roots: implications for hexose phosphorylation. 2001
Heat production by plasma membrane H+ ATPase and V0V1- H+ ATPase of maize roots: Effect of the pH. 2000
Partial characterization of UDP-glucose transporter in Golgi vesicles of maize roots. 2000
Heat production by PM-H+ ATPase and V0V1- H+ ATPase of maize roots: Effect of the pH. 2000
Hexokinase and its involvement on the cellulose biosynthesis pathway in main roots of maize (Zea mays L.). 1999
Glucose and fructose phosphorylation in maize seeds: distinct cellular sites for hexoses phosphorylation. 1999
Effect of sugars on the growth of primary roots of maize (Zea mays L.) seedling 1998
Glucokinase and fructokinase in maize seeds: distinct cellular sites for hexoses phosphorylation 1998
Glicoquinase e frutoquinase em sementes de milho: distintos sítos celulares para fosforilação de hexoses. 1998
Hexokinase regulates the NDP-sugar synthesis im maize roots 1997
A síntese de NDP-açúcar em raíz de milho é regulada pela hexoquinase 1997
Maize hexokinase is activated by NDP-sugars 1996
Subcellular and developmental distribution of hexokinase activities in maize seedlings 1996
Different Hexokinase activities induced by water during maize seeds germination 1995
Maxwell Demon in Biological Systems: Use of Glucose 6-phosphate and Hexokinase as an ATP regenerating system by the Ca2+-ATPase of sarcoplasmic reticulum and submitochondrial particles. 1992
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