Isabela Barbosa Ramos

Instituição:

Universidade Federal do Rio de Janeiro

Centro:

Centro de Ciências da Saúde

Unidade:

Instituto de Bioquímica Médica

Departamento:

Programa de Biologia Molecular e Biotecnologia

ORCID:

https://orcid.org/0000-0003-0874-7902


Formação:
  • Brown University

    | Pós-Doutorado | 2011 - 2014
  • Universidade Federal do Rio de Janeiro

    | Pós-Doutorado | 2010 - 2011
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Doutorado | 2006 - 2010
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas (Biofísica) | Mestrado | 2004 - 2006
  • Universidade Federal do Rio de Janeiro

    Ciências Biológicas | Graduação | 2000 - 2004
Laboratórios:
Nenhum laboratório cadastrado
Nuvens de Palavras:
Artigos:

(100.00% artigos com DOI)

Titulo DOI Ano
Deficiency of Brummer lipase disturbs lipid mobilization and locomotion, and impairs reproduction due to defects in the eggshell ultrastructure in the insect vector Rhodnius prolixus 10.1016/j.bbalip.2023.159442 2024
Western diet consumption by host vertebrate promotes altered gene expression on Aedes aegypti reducing its lifespan and increasing fertility following blood feeding 10.1186/s13071-023-06095-3 2024
In the fed state, autophagy plays a crucial role in assisting the insect vector Rhodnius prolixus mobilize TAG reserves under forced flight activity. 10.3389/fphys.2024.1352766 2024
Knockdown of Sec16 causes early lethality and defective deposition of the protein Rp30 in the eggshell of the vector Rhodnius prolixus 10.3389/fcell.2024.1332894 2024
Evolution of innate immunity: lessons from mammalian models shaping our current view of insect immunity 10.1007/s00360-024-01549-1 2024
Functional characterization of maternally accumulated hydrolases in the mature oocytes of the vector Rhodnius prolixus reveals a new protein phosphatase essential for the activation of the yolk mobilization and embryo development 10.3389/fphys.2023.1142433 2023
Silencing of the 20S proteasomal subunit-α6 triggers full oogenesis arrest and increased mRNA levels of the selective autophagy adaptor protein p62/SQSTM1 in the ovary of the vector Rhodnius prolixus 10.1371/journal.pntd.0011380 2023
A pro-BMP function exerted by Rhodnius prolixus Short gastrulation reveals great diversity in the role of BMP modulators during embryonic patterning 10.1098/rsob.20160023 2023
Gene identification and RNAi-silencing of p62/SQSTM1 in the vector Rhodnius prolixus reveals a high degree of sequence conservation but no apparent deficiency-related phenotypes in vitellogenic females 10.1371/journal.pone.0287488 2023
Knockdown of carnitine palmitoyltransferase I (CPT1) reduces fat body lipid mobilization and resistance to starvation in the insect vector Rhodnius prolixus 10.3389/fphys.2023.1201670 2023
Lipid Metabolism Dynamic in Triatomine Rhodnius prolixus During Acute Trypanosoma rangeli Infection 10.1016/j.actatropica.2023.107032 2023
Open questions on the functional biology of the yolk granules during embryo development 10.1002/mrd.23555 2022
Atypical strategies for cuticle pigmentation in the blood-feeding hemipteran 10.1093/genetics/iyac064 2022
Knockdown of E1- and E2-ubiquitin enzymes triggers defective chorion biogenesis and modulation of autophagy-related genes in the follicle cells of the vector Rhodnius prolixus 10.1002/jcp.30806 2022
Deficiency of acetyl-CoA carboxylase impairs digestion, lipid synthesis and reproduction in the kissing bug Rhodnius prolixus 10.3389/fphys.2022.934667 2022
Cover Image, Volume 237, Number 8, August 2022 10.1002/jcp.30860 2022
ATG3 is important for the chorion ultrastructure during oogenesis in the insect vector Rhodnius prolixus 10.3389/fphys.2021.638026 2021
Editorial: Systemic Coordination of Invertebrate Homeostasis 10.3389/fphys.2021.736185 2021
VPS38/UVRAG and ATG14, the variant regulatory subunits of the ATG6/Beclin1-PI3K complexes, are crucial for the biogenesis of the yolk organelles and are transcriptionally regulated in the oocytes of the vector Rhodnius prolixus 10.1371/journal.pntd.0009760 2021
The transition from vitellogenesis to choriogenesis triggers the downregulation of the UPR sensors IRE1 and PERK and alterations in the ER architecture in the follicle cells of the vector Rhodnius prolixus 10.1007/s00441-021-03547-z 2021
Silencing of RpATG8 impairs the biogenesis of maternal autophagosomes in vitellogenic oocytes, but does not interrupt follicular atresia in the insect vector Rhodnius prolixus 10.1371/journal.pntd.0008012 2020
Venom alkaloids against Chagas disease parasite: search for effective therapies 10.1038/s41598-020-67324-8 2020
Deficiency of ULK1/ATG1 in the follicle cells disturbs ER homeostasis and causes defective chorion deposition in the vector Rhodnius prolixus 10.1096/fj.202001396R 2020
Silencing of ATG6 and ATG8 promotes increased levels of triacylglycerol (TAG) in the fat body during prolonged starvation periods in the Chagas Disease vector Rhodnius prolixus 10.116/j.ibmb.2020.103484 2020
Biochemical characterization of digestive membrane-associated alkaline phosphatase from the velvet bean caterpillar Anticarsia gemmatalis 10.1002/arch.21591 2019
Silencing of RpATG6 impaired the yolk accumulation and the biogenesis of the yolk organelles in the insect vector R. prolixus 10.1371/journal.pntd.0006507 2018
Yolk accumulation in an insect oocyte 10.1002/mrd.22997 2018
Eggshell ultrastructure and delivery of pharmacological inhibitors to the early embryo of R. prolixus by ethanol permeabilization of the extraembryonic layers 10.1371/journal.pone.0185770 2017
Long-chain acyl-CoA synthetase 2 knockdown leads to decreased fatty acid oxidation in fat body and reduced reproductive capacity in the insect Rhodnius prolixus 10.1016/j.bbalip.2016.04.007 2016
Deficiency of glycerol-3-phosphate acyltransferase 1 decreases triacylglycerol storage and induces fatty acid oxidation in insect fat body 10.1016/j.bbalip.2016.12.004 2016
Three dimensional reconstruction by electron microscopy in the life sciences: An introduction for cell and tissue biologists 10.1002/mrd.22455 2015
Effects of chitin synthase double-stranded RNA on molting and oogenesis in the Chagas disease vector Rhodnius prolixus 10.1016/j.ibmb.2013.12.006 2014
Chitin deposition on the embryonic cuticle of Rhodnius prolixus: the reduction of CHS transcripts by CHS-dsRNA injection in females affects chitin deposition and eclosion of the first instar nymph 10.1016/j.ibmb.2013.12.004 2014
Two-pore channels function in calcium regulation in sea star oocytes and embryos 10.1242/dev.113563 2014
Calcium pathway machinery at fertilization in echinoderms 10.1016/j.ceca.2012.11.011 2013
Diversity in the fertilization envelopes of echinoderms 10.1111/ede.12012 2013
Yolk organelles of insect oocytes - freeze-fracture of isolated acidocalcisomes 10.1002/mrd.22157 2013
Silencing of maternal Heme Binding Protein causes embryonic mitochondrial dysfunction and impairs embryogenesis in the blood sucking insect Rhodnius prolixus 10.1074/jbc.m113.504985 2013
Yolk hydrolases in the eggs of Anticarsia gemmatalis Hubner (Lepidoptera: Noctuidae): A role for inorganic polyphosphate towards yolk mobilization 10.1016/j.jinsphys.2013.09.008 2013
New insights into the in situ microscopic visualization and quantification of inorganic polyphosphate stores by 4',6-diamidino-2-phenylindole (DAPI)-staining 10.4081/ejh.2013.e34 2013
Dysferlin is essential for endocytosis in the sea star oocyte 10.1016/j.ydbio.2013.12.018 2013
The biology of the germ line in echinoderms 10.1002/mrd.22223 2013
Calreticulin expression levels and endoplasmic reticulum during late oogenesis and early embryogenesis of Rhodnius prolixus Stahl 10.1007/s11033-010-0290-0 2011
Olfactory ensheathing cells as putative host cells for Streptococcus pneumoniae: Evidence of bacterial invasion via mannose receptor-mediated endocytosis 10.1016/j.neures.2010.12.015 2011
Transcriptome and gene expression profile of ovarian follicle tissue of the triatomine bug Rhodnius prolixus 10.1016/j.ibmb.2011.06.004 2011
Microscopic and molecular characterization of ovarian follicle atresia in Rhodnius prolixus Stahl under immune challenge 10.1016/j.jinsphys.2011.04.010 2011
Acidocalcisomes as Calcium- and Polyphosphate-Storage Compartments during Embryogenesis of the Insect Rhodnius prolixus Stahl 10.1371/journal.pone.0027276 2011
Calcium and polyphosphate-containing acidocalcisomes in chicken egg yolk 10.1042/BC20100011 2010
The effect of lufenuron, a chitin synthesis inhibitor, on oogenesis of Rhodnius prolixus 10.1016/j.pestbp.2010.04.013 2010
Calcium and polyphosphate-containing acidic granules of sea urchin eggs are similar to acidocalcisomes but are not the targets for NAADP 10.1042/BJ20091956 2010
Proton-pyrophosphatase and polyphosphate in acidocalcisome-like vesicles from oocytes and eggs of Periplaneta americana 10.1016/j.ibmb.2008.11.003 2009
Inorganic polyphosphate inhibits an aspartic protease-like activity in the eggs of Rhodnius prolixus (Stahl) and impairs yolk mobilization in vitro 10.1002/jcp.21975 2009
Interplay between acid phosphatase and cysteine proteases in mediating 10.1016/j.jinsphys.2008.04.005 2008
Polyphosphate polymers during early embryogenesis of Periplaneta americana 10.1016/j.jinsphys.2008.07.018 2008
Calcium-regulated fusion of yolk granules is important for yolk degradation during early embryogenesis of Rhodnius prolixus 10.1242/jeb.02652 2007
A chitin-like component in Aedes aegypti eggshells, eggs and ovaries 10.1016/j.ibmb.2007.07.017 2007
Calcium-regulated fusion of yolk granules during early embryogenesis of Periplaneta americana 10.1002/mrd.20560 2006
Eventos:

(0.00% eventos com DOI)

Titulo DOI Ano
Characterization of the molecular mechanisms that regulate the biogenesis of the yolk organelles during oogenesis of the insect vector Rhodnius prolixus 2019
ATG1 in the Follicular Epithelium of the Insect Vector Rhodnius prolixus is Important for the Chorion Synthesis 2019
Autophagosomes in oocytes of R. prolixus 2018
AtG1 in the yolk organelles during oogenesis of the vector R. prolixus 2018
Autophagy in the follicular atresia of the insect vector R. prolixus 2018
ATG6 is Required for the Endocytosis of Yolk Proteins and yolk organelles biogenesis During Oogenesis of the Insect Vector Rhodnius prolixus 2017
ATG1 in the degradation of yolk organelles during oogenesis and embryogenesis of the insect vector Rhodnius prolixus. 2017
ATG6 is required for the endocytosis of yolk proteins during oogenesis of the insect vector Rhodnius prolixus 2016
Autophagosomes In Oocytes And Eggs Of The Insect Vector Rhodnius Prolixus 2016
Delivery of pharmacological inhibitors to the early embryo of R. prolixus by ethanol diffusion through the egg chorion and detergent-permeabilization of the extraembryonic layers 2016
Atg6 during development of the insect vector Rhodnius prolixus 2015
Characterization of autophagy related protein 8 (Atg8) during oogenesis and early embryogenesis of the insect vector of Chagas Disease Rhodnius prolixus 2015
NAADP-dependent Ca2+ signaling - ARCs and TPCs in sea star oocytes/eggs 2013
Proteolytic Activity and Investigation of Putative Cysteine Protease Inhibitors in Anticarsia gemmatalis Eggs 2010
Calcium and Poliphosphate containing acidic granules of sea urchin eggs are similar to acidocalcisomes but are not the targets of NAADP 2010
Calcium and polyphosphate containing acidocalcisomes in chicken egg yolk 2010
Cotribution of analytical electron microscopy to the study of acidic calcium stores in parasites and other eukaryotic models 2010
Inorganic polyphosphate inhibts an aspartic protease-like activity in the eggs of Rhodnius prolixus Stahl and impairs yolk mobilization in vitro 2009
Inorganic polyphosphate storage and inhibition of an aspartic protease-like activity in eggs of Rhodnius prolixus 2009
Cloning and complete sequencing of cDNA encoding Calmodulin from eggs of Rhodnius prolixus 2007
study of Lisossomal-like hydrolases during periplaneta americana early embryogenesis 2007
PARTIAL CHARACTERIZATION OF ABC TRANSPORTER PROTEINS IN A. AEGYPTI AND POSSIBLE RELATIONSHIP TO TEMEPHOS INSECTICIDE RESISTANCE. 2007
Characterization of Polyphosphate in the eggs of Rhodnius prolixus 2007
Calcium-regulated fusion of yolk granules is important for yolk degradation during early embryogenesis of Rhodnius prolixus 2006
Study of proteinases and acid phosphatase during periplaneta americana early embryogenesis 2006
Inorganic Polyphosphate characterization on the early embryogenesis of periplaneta americana 2006
The yolk granules dynamics during early embryogenesis of Periplaneta americana showed by differential acidification and fusion of this organelles 2005
The yolk granules dynamics during Periplaneta americana embryogenesis 2005
Structural and Biochemical Characterization of Embryonic Cuticle of Rhodnius prolixus 2005
Characterization of Phosphate and Poliphosphate in the eggs of Periplaneta americana 2005
The role of H+PPase on yolk granules acidification from Periplaneta americana and its participation in this insect embryogenesis. 2004
The role of H+PPase on yolk granules acidification from Periplaneta americana? 2003
Studies on Protein-Protein and Protein-Nucleic Acid Interactions Involved on MS2 Bacteriophage Stability 2002
Estudo das Interações Proteína-Proteína e Proteína-Ácido Nucleico envolvidas na Estabilidade do Capsídeo Protéico do Bacteriófago MS2 2002
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