Célio Geraldo Freire de Lima
Instituição:
Universidade Federal do Rio de Janeiro
Centro:
Centro de Ciências da Saúde
Unidade:
Instituto de Biofísica Carlos Chagas Filho
Departamento:
Programa de Imunobiologia/Biof
Formação:
-
National Jewish Medical and Reseach Center
| Pós-Doutorado | 2002 - 2004
-
Instituto Oswaldo Cruz
| Pós-Doutorado | 2000 - 2002
-
Universidade Federal do Rio de Janeiro
Ciências (Microbiologia) | Doutorado | 1996 - 2000
-
Instituto Oswaldo Cruz
Biologia Parasitária | Mestrado | 1992 - 1995
-
Universidade Gama Filho
Biologia | Graduação | 1987 - 1990
Laboratórios:
Nuvens de Palavras:
Artigos:
(91.26% artigos com DOI)
| Titulo | DOI | Ano |
|---|---|---|
| A Comparative Analysis of Innate Immune Responses and the Structural Characterization of Spike from SARS-CoV-2 Gamma Variants and Subvariants | 10.3390/microorganisms12040720 | 2024 |
| Inhibition of Microbicidal Activity of Canine Macrophages DH82 Cell Line by Capsular Polysaccharides from Cryptococcus neoformans | 10.3390/jof10050339 | 2024 |
| Seasoning to Kill: the Example of the Natural Amide Piperine and Its Potential in the Design of New Antiparasitic Drugs | 10.21577/0103-5053.20240085 | 2024 |
| The Blessed Union of Glycobiology and Immunology: A Marriage That Worked | 10.3390/medicines10020015 | 2023 |
| Expression of O-glycosylated oncofetal fibronectin in alternatively activated human macrophages | 10.1007/s12026-022-09321-9 | 2023 |
| Non-self glycan structures as possible modulators of cancer progression: would polysaccharides from Cryptococcus spp. impact this phenomenon? | 10.1007/s42770-023-00936-0 | 2023 |
| Increased Expression of the Pathological O-glycosylated Form of Oncofetal Fibronectin in the Multidrug Resistance Phenotype of Cancer Cells | 10.1016/j.matbio.2023.03.002 | 2023 |
| Special Issue: -Parasitic Infection and Host Immunity-: Editorial | 10.3390/microorganisms11041027 | 2023 |
| Increased Trypanosoma cruzi Growth during Infection of Macrophages Cultured on Collagen I Matrix | 10.3390/life13041063 | 2023 |
| Bittersweet Sugars: How Unusual Glycan Structures May Connect Epithelial-to-Mesenchymal Transition and Multidrug Resistance in Cancer | 10.3390/medicines10060036 | 2023 |
| Immune Responses in Leishmaniases: An Overview | 10.3390/tropicalmed7040054 | 2022 |
| Glycobiology of Cancer: Sugar Drives the Show | 10.3390/medicines9060034 | 2022 |
| The Sweet Side of Fungal Infections: Structural Glycan Diversity and Its Importance for Pathogenic Adaptation | 10.3390/medicines9060037 | 2022 |
| Cellular Stress and Senescence Induction during Trypanosoma cruzi Infection | 10.3390/tropicalmed7070129 | 2022 |
| Cryptococcus: History, Epidemiology and Immune Evasion | 10.3390/app12147086 | 2022 |
| SARS-CoV-2?s Variants of Concern: A Brief Characterization | 10.3389/fimmu.2022.834098 | 2022 |
| O POTENCIAL DA XANTONA NATURAL α-MANGOSTINA NO DESENVOLVIMENTO DE NOVOS AGENTES ANTI-INFECCIOSOS: UMA REVISÃO | 10.21577/0100-4042.20170954 | 2022 |
| A Novel Protocol for the Synthesis of 1,2,4-Oxadiazoles Active against Trypanosomatids and Drug-Resistant Leukemia Cell Lines | 10.3390/tropicalmed7120403 | 2022 |
| Humoral response in Leishmaniasis | 10.3389/fcimb.2022.1063291 | 2022 |
| Pulmonary Fibrosis and Hypereosinophilia in TLR9-/- Mice Infected by Cryptococcus gattii | 10.3390/pathogens11090987 | 2022 |
| The role of Toll-like receptor 9 in a murine model of Cryptococcus gattii infection | 10.1038/s41598-021-80959-5 | 2021 |
| Critically ill COVID-19 patients exhibit hyperactive cytokine responses associated with effector exhausted senescent T cells in acute infection | 10.1093/infdis/jiab425 | 2021 |
| X-linked immunodeficient (XID) mice exhibit high susceptibility to Cryptococcus gattii infection | 10.1038/s41598-021-97041-9 | 2021 |
| Autoimmune Disorders & COVID-19 | 10.3390/medicines8100055 | 2021 |
| COVID-19 Infection and Neuropathological Features | 10.3390/medicines8100059 | 2021 |
| Drug repurposing for Chagas disease: In vitro assessment of nimesulide against Trypanosoma cruzi and insights on its mechanisms of action | 10.1371/journal.pone.0258292 | 2021 |
| How to B(e)-1 Important Cell During Leishmania Infection | 10.3389/fcimb.2019.00424 | 2020 |
| Piperine Inhibits TGF-β Signaling Pathways and Disrupts EMT-related Events in Human Lung Adenocarcinoma Cells | 10.3390/medicines7040019 | 2020 |
| DH82 Canine and RAW264.7 Murine Macrophage Cell Lines Display Distinct Activation Profiles Upon Interaction With Leishmania infantum and Leishmania amazonensis | 10.3389/fcimb.2020.00247 | 2020 |
| Combined therapy with adipose tissue-derived mesenchymal stromal cells and meglumine antimoniate controls lesion development and parasite load in murine cutaneous leishmaniasis caused by Leishmania amazonensis | 10.1186/s13287-020-01889-z | 2020 |
| Protective role of chlorogenic acid on DNA damage caused by ochratoxin A exposure | 10.24215/15142590e049 | 2020 |
| The emerging role of neutrophil extracellular traps in severe acute respiratory syndrome coronavirus 2 (COVID-19) | 10.1038/s41598-020-76781-0 | 2020 |
| Theft and Reception of Host Cell's Sialic Acid: Dynamics of Trypanosoma Cruzi Trans-sialidases and Mucin-Like Molecules on Chagas' Disease Immunomodulation | 10.3389/fimmu.2019.00164 | 2019 |
| The role of TLR9 on Leishmania amazonensis infection and its influence on intranasal LaAg vaccine efficacy | 10.1371/journal.pntd.0007146 | 2019 |
| Design, Synthesis, Trypanocidal Activity, and Studies on Human Albumin Interaction of Novel S-Alkyl-1,2,4-triazoles | 10.21577/0103-5053.20190033 | 2019 |
| Targeting the Hexosamine Biosynthetic Pathway Prevents Plasmodium Developmental Cycle and Disease Pathology in Vertebrate Host | 10.3389/fmicb.2019.00305 | 2019 |
| Immunomodulatory Role of Capsular Polysaccharides Constituents of Cryptococcus neoformans | 10.3389/fmed.2019.00129 | 2019 |
| B-1 Cells May Drive Macrophages Susceptibility to Trypanosoma cruzi Infection | 10.3389/fmicb.2019.01598 | 2019 |
| Minthostachys verticillata essential oil activates macrophage phagocytosis and modulates the innate immune response in a murine model of Enterococcus faecium mastitis | 10.1016/j.rvsc.2019.07.015 | 2019 |
| B-1 lymphocytes are able to produce IL-10, but is not pathogenic during Leishmania (Leishmania) amazonensis infection | 10.1016/j.imbio.2019.10.006 | 2019 |
| Targeting the Hexosamine Biosynthetic Pathway Prevents Plasmodium Developmental Cycle and Disease Pathology in Vertebrate Host | 10.3389/fmicb.2019.00305 | 2019 |
| Circulating Plasma MicroRNA-208a as Potential Biomarker of Chronic Indeterminate Phase of Chagas Disease | 10.3389/fmicb.2018.00269 | 2018 |
| Prevalence of IgG Autoantibodies against GD3 Ganglioside in Acute Zika Virus Infection | 10.3389/fmed.2018.00025 | 2018 |
| Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses | 10.3389/fonc.2018.00081 | 2018 |
| Antibody Repertoires Identify β-Tubulin as a Host Protective Parasite Antigen in Mice Infected With Trypanosoma cruzi | 10.3389/fimmu.2018.00671 | 2018 |
| NH36 and F3 Antigen-Primed Dendritic Cells Show Preserved Migrating Capabilities and CCR7 Expression and F3 Is Effective in Immunotherapy of Visceral Leishmaniasis | 10.3389/fimmu.2018.00967 | 2018 |
| Trypanosoma cruzi Infection Induces Cellular Stress Response and Senescence-Like Phenotype in Murine Fibroblasts | 10.3389/fimmu.2018.01569 | 2018 |
| Immunomodulating role of IL-10-Producing B cells in Leishmania amazonensis infection | 10.1016/j.cellimm.2018.08.014 | 2018 |
| Involvement of the capsular GalXM-induced IL-17 cytokine in the control of Cryptococcus neoformans infection | 10.1038/s41598-018-34649-4 | 2018 |
| Challenges in the chemotherapy of Chagas disease: Looking for possibilities related to the differences and similarities between the parasite and host | 10.4331/wjbc.v8.i1.57 | 2017 |
| Implication of Apoptosis for the Pathogenesis of Trypanosoma cruzi Infection | 10.3389/fimmu.2017.00518 | 2017 |
| B-1 cells modulate the murine macrophage response to infection | 10.4331/wjbc.v8.i2.151 | 2017 |
| Canine Macrophage DH82 Cell Line As a Model to Study Susceptibility to Trypanosoma cruzi Infection | 10.3389/fimmu.2017.00604 | 2017 |
| Dependency of B-1 Cells in the Maintenance of Splenic Interleukin-10 Producing Cells and Impairment of Macrophage Resistance in Visceral Leishmaniasis | 10.3389/fmicb.2017.00978 | 2017 |
| Decoding the Role of Glycans in Malaria | 10.3389/fmicb.2017.01071 | 2017 |
| Role of Inactive and Active Trypanosoma cruzi Trans-sialidases on T Cell Homing and Secretion of Inflammatory Cytokines | 10.3389/fmicb.2017.01307 | 2017 |
| Host-Toxoplasma gondii coadaptation leads to fine tuning of the immune response | 10.3389/fimmu.2017.01080 | 2017 |
| Host resistance to visceral leishmaniasis: prevalence and prevention | 10.1586/14787210.2016.1160779 | 2016 |
| Phenolic acid protects of renal damage induced by ochratoxin A in a 28-days-oral treatment in rats | 10.1016/j.etap.2016.03.004 | 2016 |
| The Sweet Side of Immune Evasion: Role of Glycans in the Mechanisms of Cancer Progression | 10.3389/fonc.2016.00054 | 2016 |
| Role of Trypanosoma cruzi Trans-sialidase on the Escape from Host Immune Surveillance | 10.3389/fmicb.2016.00348 | 2016 |
| The Contribution of Immune Evasive Mechanisms to Parasite Persistence in Visceral Leishmaniasis | 10.3389/fimmu.2016.00153 | 2016 |
| Modulation of Cell Sialoglycophenotype: A Stylish Mechanism Adopted by Trypanosoma cruzi to Ensure Its Persistence in the Infected Host | 10.3389/fmicb.2016.00698 | 2016 |
| Lipid Body Organelles within the Parasite Trypanosoma cruzi: A Role for Intracellular Arachidonic Acid Metabolism | 10.1371/journal.pone.0160433 | 2016 |
| The Effectiveness of Natural Diarylheptanoids against Trypanosoma cruzi: Cytotoxicity, Ultrastructural Alterations and Molecular Modeling Studies | 10.1371/journal.pone.0162926 | 2016 |
| Immune Escape Strategies of Malaria Parasites | 10.3389/fmicb.2016.01617 | 2016 |
| Capsular polysaccharides from Cryptococcus neoformans modulate production of neutrophil extracellular traps (NETs) by human neutrophils | 10.1038/srep08008 | 2015 |
| Immune Evasion Strategies of Trypanosoma cruzi | 10.1155/2015/178947 | 2015 |
| Macrophage Polarization in Infectious Diseases | 10.4172/2155-9899.1000294 | 2015 |
| Expression of leukosialin (CD43) defines a major intrahepatic T cell subset associated with protective responses in visceral leishmaniasi | 10.1186/s13071-015-0721-9 | 2015 |
| Modulation of Intrathymic Sphingosine-1-Phosphate Levels Promotes Escape of Immature Thymocytes to the Periphery with a Potential Proinflammatory Role in Chagas Disease | 10.1155/2015/709846 | 2015 |
| Compositional and immunobiological analyses of extracellular vesicles released by C andida albicans | 10.1111/cmi.12374 | 2015 |
| The PGE2/IL-10 Axis Determines Susceptibility of B-1 Cell-Derived Phagocytes (B-1CDP) to Leishmania major Infection | 10.1371/journal.pone.0124888 | 2015 |
| Neutrophils Increase or Reduce Parasite Burden in Trypanosoma cruzi-Infected Macrophages, Depending on Host Strain: Role of Neutrophil Elastase | 10.1371/journal.pone.0090582 | 2014 |
| Infection with Leishmania major Induces a Cellular Stress Response in Macrophages | 10.1371/journal.pone.0085715 | 2014 |
| Early Double-Negative Thymocyte Export in Trypanosoma cruzi Infection Is Restricted by Sphingosine Receptors and Associated with Human Chagas Disease | 10.1371/journal.pntd.0003203 | 2014 |
| Trans-sialidase from Trypanosoma cruzi enhances the adhesion properties and fibronectin-driven migration of thymocytes | 10.1016/j.micinf.2013.02.003 | 2013 |
| Modulation of glutathione intracellular levels alters the spontaneous proliferation of lymphocyte from HTLV-1 infected patients | 10.1016/j.imbio.2013.04.002 | 2013 |
| Pulmonary Anti-fibrotic Mechanisms of ATLa, An Aspirin-Triggered Lipoxin A 4 Synthetic Analog | 10.1165/rcmb.2012-0462oc | 2013 |
| Inhibitory Effects of Trypanosoma cruzi Sialoglycoproteins on CD4+ T Cells Are Associated with Increased Susceptibility to Infection | 10.1371/journal.pone.0077568 | 2013 |
| The short chain fatty acid sodium butyrate regulates the induction of CD1a in developing dendritic cells | 10.1016/j.imbio.2010.07.004 | 2011 |
| Host Cell Lipid Bodies Triggered by Trypanosoma cruzi Infection and Enhanced by the Uptake of Apoptotic Cells Are Associated With Prostaglandin E2 Generation and Increased Parasite Growth | 10.1093/infdis/jir432 | 2011 |
| Extracellular Vesicles from Cryptococcus neoformans Modulate Macrophage Functions | 10.1128/iai.01171-09 | 2010 |
| Proinflammatory Clearance of Apoptotic Neutrophils Induces an IL-12lowIL-10high Regulatory Phenotype in Macrophages | 10.4049/jimmunol.1000017 | 2010 |
| ATP-induced apoptosis involves a Ca2+-independent phospholipase A2 and 5-lipoxygenase in macrophages | 10.1016/j.prostaglandins.2008.09.004 | 2009 |
| Arrest of oogenesis in the bug Rhodnius prolixus challenged with the fungus Aspergillus niger is mediated by immune response-derived PGE2 | 10.1016/j.jinsphys.2008.10.019 | 2009 |
| Induction of autophagy correlates with increased parasite load of Leishmania amazonensis in BALB/c but not C57BL/6 macrophages | 10.1016/j.micinf.2008.11.006 | 2009 |
| Transcriptional and Translational Regulation of TGF- Production in Response to Apoptotic Cells | 10.4049/jimmunol.181.5.3575 | 2008 |
| Capsular polysaccharides galactoxylomannan and glucuronoxylomannan from Cryptococcus neoformans induce macrophage apoptosis mediated by Fas ligand | 10.1111/j.1462-5822.2008.01125.x | 2008 |
| Immunological consequences of apoptotic cell phagocytosis | 2007 | |
| Oxidants Selectively Reverse TGF- Suppression of Proinflammatory Mediator Production | 10.4049/jimmunol.176.2.1209 | 2006 |
| Apoptotic Cells, through Transforming Growth Factor-beta, Coordinately Induce Anti-inflammatory and Suppress Pro-inflammatory Eicosanoid and NO Synthesis in Murine Macrophages | 10.1074/jbc.m605146200 | 2006 |
| Apoptotic cell uptake induces macrophage lipid body formation: Impact to intracellular pathogen infection | 2006 | |
| The importance of aberrant T cell responses in Chagas disease | 2005 | |
| Cissampelos sympodialis Eichl (Menispermaceae) leaf extract induces interleukin-10-dependent inhibition of Trypanosoma cruzi killing by macrophages | 10.1590/S0100-879X2003000200006 | 2003 |
| Proinflammatory and Cytotoxic Effects of Hexadecylphosphocholine (Miltefosine) against Drug-Resistant Strains of Trypanosoma cruzi | 10.1128/aac.46.11.3472-3477.2002 | 2002 |
| Uptake of apoptotic cells drives the growth of a pathogenic trypanosome in macrophages | 10.1038/35003208 | 2000 |
| The macrophage haunted by cell ghost: A pathogen grows | 2000 | |
| Lymphocytes apoptosis: A double-edged sword in host cell-mediated immunity against Trypanosoma cruzi | 1998 | |
| Pro-apoptotic activity of a Trypanosoma cruza ceramide-containing glycolipid turned on in macrophages by interferon-gamma | 1998 | |
| A commom messeger pathway transduce host and parasite-derived molecular signals subverting cell-mediated immune responses | 1996 | |
| Chronic experimental Chagas'disease: Functional syngeneic T-B cooperation in vitro in the absence of exogenous stimulus | 1996 | |
| Control of differential CD4 T lymphocyte behavior in vitro is ditected by the patter of CD molecule involvement | 1994 |
Eventos:
(0.00% eventos com DOI)